grepafloxacin
(AIJTTZAVMXIJGM-UHFFFAOYSA-N)
Structure
- SMILES
- CC1NCCN(C1)c1cc2c(c(c1F)C)c(=O)c(cn2C1CC1)C(=O)O
- Type(s)
- Approved; Investigational; Withdrawn
- ATC code(s)
- J01MA11
- Molecular Formula:
- C19H22FN3O3
- Molecular Weight:
- 359.395
- Log P:
- 2.6740
- Hydrogen Bond Acceptor:
- 6
- Hydrogen Bond Donor:
- 2
- TPSA:
- 74.57
- CAS Number(s):
- 119914-60-2; 146863-02-7
Synonym(s)
1.
grepafloxacin
2.
(+--)-1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
3.
(+--)-1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid monohydrochloride
4.
3-quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-
5.
3-quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-, monohydrochloride, (+--)-
6.
OPC 17116
7.
OPC-17116
8.
Raxar
9.
grepafloxacin HCl
10.
grepafloxacin hydrochloride
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Anxiety | FAERS: 1 | US FAERS | |
| 2 | Hypotension | FAERS: 1 | US FAERS | |
| 3 | Nausea | FAERS: 1 | US FAERS | |
| 4 | Pruritus | FAERS: 1 | US FAERS | |
| 5 | Vomiting | FAERS: 1 | US FAERS | |
| 6 | Long QT Syndrome | 12052667 21158687 | CTD | |
| 7 | Torsades de Pointes | 15001976 | CTD |
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