Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 1293
Aptamer sequence: ACCACCGGCCCGAGATAGTCTAGACCACTATGTTGTTGTGCTTACTGCTGTGTGGTGTGG
Target unique ID: 5353447
Aptamer ID Aptamer descriptor Target chemistry Target name Affinity Binding Conditions/Buffer PubMed ID
Apta_1231 BT 31 Molecule Brevetoxin 2 1296 nM 50 mM Tris, pH 7.5, and 10 mM MgCl2 25725463
Structure information of aptamer
Aptamer Sequence: ACCACCGGCCCGAGATAGTCTAGACCACTATGTTGTTGTGCTTACTGCTGTGTGGTGTGG
The optimal secondary structure in dot-bracket notation: (((((((((.(((.(((((.......))))).)))...........)))).)))))....
The centroid secondary structure in dot-bracket notation: (((((((((.(((.(((((.......))))).)))...........)))).)))))....
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
Type Detail Type Detail
Aptamer ID Apta_1231 Description BT 31
Aptamer chemistry DNA Length 60 nt
GC content 53.3% Molecular weight 18,519.83 Da
Molarity of 1 μg/μl solution 54.00 μM Number of G-quadruplexes No QGRS found
G-Score N/A Function Aptasensor
Sequence ACCACCGGCCCGAGATAGTCTAGACCACTATGTTGTTGTGCTTACTGCTGTGTGGTGTGG
Applications Detection of BTX-2 in food samples
Target information
Type Detail Type Detail
PubChem ID 5353447 Molecular name Brevetoxin 2
Molecular formula C50H70O14 Molecular weight 895.1
IUPAC name 2-[[(21Z)-12-hydroxy-1,3,11,24,31,41,44-heptamethyl-39-oxo-2,6,10,15,19,25,29,34,38,43,47-undecaoxaundecacyclo[26.22.0.03,26.05,24.07,20.09,18.011,16.030,48.033,46.035,44.037,42]pentaconta-21,40-dien-14-yl]methyl]prop-2-enal InChIKey LYTCVQQGCSNFJU-KTKRTIGZSA-N
LogP 5.472 Topological polar surface area 155.9
Hydrogen bond acceptor 14 Hydrogen bond donor 1

Synonym(s):
Brevetoxin 2; brevetoxin pbtx-2; 79580-28-2; Brevetoxin T 34; 2-[[(21Z)-12-hydroxy-1,3,11,24,31,41,44-heptamethyl-39-oxo-2,6,10,15,19,25,29,34,38,43,47-undecaoxaundecacyclo[26.22.0.03,26.05,24.07,20.09,18.011,16.030,48.033,46.035,44.037,42]pentaconta-21,40-dien-14-yl]methyl]prop-2-enal; Brevetoxin PbTx 2; GB 2 toxin; T-34 toxin; GB 2 (Gymnodinium); Toxin T-34; T 4-7 toxin; Ptychodiscus brevis toxin 2; GB 2; T 4-7

Activity data

No relevant experimental diagram

 Interaction ID 1293
Target type Molecule
Target unique ID 5353447
Activity 1296 nM
Binding Conditions/Buffer

50 mM Tris, pH 7.5, and 10 mM MgCl2
Assay

N/A
PubMed ID 25725463
Similar aptamers
Aptamer ID Aptamer chemistry Sequence Similarity
Apta_742 DNA ATCGTCTGCTCCGTCCAATAGGACCGATAGGAACCACGGACTGCATGTTTCTGCATTTGACGTGGTTTGGTGTGAGGTCGTGC 57.83%
Apta_738 DNA ATCGTCTGCTCCGTCCAATACCTGCATATACACTTTGCATGTGGTTTGGTGTGAGGTCGTGC 56.45%
Apta_974 DNA CATGGTGTCAATACTATACCTTTTGCCGATGGTAACAGTTGGTGGTATCC 55.00%
Apta_740 DNA ATCGTCTGCTCCGTCCAATAAACCTGCATAATTTATAAGTCTAGACTGCTGCATTTGGTGTGAGGTCGTGC 54.93%
Apta_655 DNA CCTGCACCTCGTCCAGCATGCACACCGATGGCGGTCCTGTTTTACGGTAGCTTATATGCAGGGGGTGTGCGTG 54.79%
Apta_553 DNA TGTACCGTCTGAGCGATTCGTACGAACGGCTTTGTACTGTTTGCACTGGCGGATTTAGCCAGTCAGTGTTAAGGAGTGC 54.43%
Apta_736 DNA ATCGTCTGCTCCGTCCAATATGATGACACCTGCATAATTTATAGTGAGTCTTGATTCACGCTGCATTTGGTGTGAGGTCGTGC 54.22%
Apta_743 DNA ATCGTCTGCTCCGTCCAATATCCGAGCAAGAACTCATATTGCATTATTTATAGCTACGCGCTGCATTTGGTGTGAGGTCGTGC 54.22%
Apta_140 DNA GGCAGGAAGACAAACACGATGGGGGGGTATGATTTGATGTGGTTGTTGCATGATCGTGGTCTGTGGTGCTGT 54.17%
Apta_417 DNA GGCAGGAAGACAAACACCAGGTGAGGGAGACGACGCGAGTGTTAGATGGTAGCTGTTGGTCTGTGGTGCTGT 54.17%
Apta_536 DNA ATCCGTCACACCTGCTCTCGAATAGAGTACTCGATACTGACTTTATTTACCGTCTGGTGTTGGCTCCCGTAT 54.17%
Apta_899 DNA ATCCGTCACACCTGCTCTCGAATAGAGTATTCGATACTGACTTTATTTACCGTCTGGTGTTGGCTCCCGTAT 54.17%
Apta_731 DNA AAGGAGCAGCGTGGAGGATACTCTAATTGCCGTATAAGGTCAGGGGGTTGGTTGGTTCCTAGTGCTTAGGGTGTGTCGTCGTGGT 54.12%
Apta_737 DNA ATCGTCTGCTCCGTCCAATAGTGCATTGAAACTTCTGCATCCTCGTTTGGTGTGAGGTCGTGC 53.97%
Apta_173 DNA AGCAGCACAGAGGTCAGATGGCAGGTTTCGACGTACAATGCTATGGAGGCTTTATGATCGCCTATGCGTGCTACCGTGAA 53.75%
Apta_739 DNA ATCGTCTGCTCCGTCCAATAGCGTGCATTGGTTTACTGCATCCGTGAAACTGGGCTTTGGTGTGAGGTCGTGC 53.42%
Apta_217 DNA CGCCTGATTAGCGATACTCAGGCGTTGGGTGGGTGGGTGGG 53.33%
Apta_335 DNA ACCGGGCGTACACCGTCGCGGCACATGTCTGAATGCGTTTAGTCTCTGTG 53.33%
Apta_651 DNA CCTGCACCTCGTCCAGCATGCACACCGATGGCGGTCCTGTTTAGGGGGTGTGCGTG 53.33%
Apta_753 DNA GGGCACAGACGGAAGATGAGAATTGTGGGGCTTAGTATAGTGAGGTGCGTGT 53.33%

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AptaDB is an online database we developed to integrate comprehensive information about aptamer.
The detail of this database is described here:

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