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CompoundTarget IDProtein nameProtein familyGene symbolGene IDOrganismScoreRank

[1] CHEMBL5653589

Original SMILES:
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12

Prepared SMILES:
Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1

P34913Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) ...AB hydrolase superfamily, Epoxide hydrolase familyEPHX22053;Homo sapiens (Human)3.180891
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)2.930022
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)2.523333
P00918Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA2760;Homo sapiens (Human)2.517774
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)2.488645
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)2.481416
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)2.28847
P48736Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) ...PI3/PI4-kinase familyPIK3CG5294;Homo sapiens (Human)2.204968
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)2.136559
P0DMS8Adenosine receptor A3G-protein coupled receptor 1 familyADORA3140;Homo sapiens (Human)2.0241410
P23141Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) ...Type-B carboxylesterase/lipase familyCES11066;Homo sapiens (Human)1.9862211
Q13547Histone deacetylase 1 (HD1) (EC 3.5.1.98)Histone deacetylase family, HD type 1 subfamilyHDAC13065;Homo sapiens (Human)1.9772112
P42345Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein ...PI3/PI4-kinase familyMTOR2475;Homo sapiens (Human)1.956313
P30542Adenosine receptor A1G-protein coupled receptor 1 familyADORA1134;Homo sapiens (Human)1.8899614
Q8NER1Transient receptor potential cation channel subfamily V member 1 (TrpV1) ...Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamilyTRPV17442;Homo sapiens (Human)1.8786315
P42336Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) ...PI3/PI4-kinase familyPIK3CA5290;Homo sapiens (Human)1.8764316
P41594Metabotropic glutamate receptor 5 (mGluR5)G-protein coupled receptor 3 familyGRM52915;Homo sapiens (Human)1.8621417
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.8100618
P52732Kinesin-like protein KIF11 (Kinesin-like protein 1) (Kinesin-like spindle protein HKSP) ...TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, BimC subfamilyKIF113832;Homo sapiens (Human)1.7359619
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)1.7322120
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)1.7313821
Q16790Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA9768;Homo sapiens (Human)1.7138422
Q99705Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein ...G-protein coupled receptor 1 familyMCHR12847;Homo sapiens (Human)1.6988223
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)1.6938324
P283355-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) ...G-protein coupled receptor 1 familyHTR2C3358;Homo sapiens (Human)1.6929325
P11511Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen ...Cytochrome P450 familyCYP19A11588;Homo sapiens (Human)1.5589126
P00915Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA1759;Homo sapiens (Human)1.517227
P282215-hydroxytryptamine receptor 1D (5-HT-1D) (5-HT1D) (Serotonin 1D alpha receptor) (5-HT-1D-alpha) ...G-protein coupled receptor 1 familyHTR1D3352;Homo sapiens (Human)1.5063928
P09874Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like ...PARP1142;Homo sapiens (Human)1.4477529
O43683Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)Protein kinase superfamily, Ser/Thr protein kinase family, BUB1 subfamilyBUB1699;Homo sapiens (Human)1.4453830
P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR17046;Homo sapiens (Human)1.4347331
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.4233832
P34972Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)G-protein coupled receptor 1 familyCNR21269;Homo sapiens (Human)1.4205633
P25103Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1)G-protein coupled receptor 1 familyTACR16869;Homo sapiens (Human)1.415934
O43570Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA12771;Homo sapiens (Human)1.4099535
P15538Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid ...Cytochrome P450 familyCYP11B11584;Homo sapiens (Human)1.3748836
P29274Adenosine receptor A2aG-protein coupled receptor 1 familyADORA2A135;Homo sapiens (Human)1.3715637
Q02127Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase)Dihydroorotate dehydrogenase family, Type 2 subfamilyDHODH1723;Homo sapiens (Human)1.3586838
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.3537639
P00742Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved ...Peptidase S1 familyF102159;Homo sapiens (Human)1.3467340
P41597C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) ...G-protein coupled receptor 1 familyCCR2729230;Homo sapiens (Human)1.3444241
P00374Dihydrofolate reductase (EC 1.5.1.3)Dihydrofolate reductase familyDHFR1719;Homo sapiens (Human)1.3401942
O76074cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)Cyclic nucleotide phosphodiesterase familyPDE5A8654;Homo sapiens (Human)1.3026243
P282225-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (S12) (Serotonin 1D beta receptor) ...G-protein coupled receptor 1 familyHTR1B3351;Homo sapiens (Human)1.3001844
P29275Adenosine receptor A2bG-protein coupled receptor 1 familyADORA2B136;Homo sapiens (Human)1.2947545
P10275Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C ...Nuclear hormone receptor family, NR3 subfamilyAR367;Homo sapiens (Human)1.2882346
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)1.2800147
P32239Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R)G-protein coupled receptor 1 familyCCKBR887;Homo sapiens (Human)1.277548
P415955-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)G-protein coupled receptor 1 familyHTR2B3357;Homo sapiens (Human)1.2375349
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)1.2357450

[2] CHEMBL3752910

Original SMILES:
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C

Prepared SMILES:
Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F

P34913Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) ...AB hydrolase superfamily, Epoxide hydrolase familyEPHX22053;Homo sapiens (Human)3.180891
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)2.930022
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)2.523333
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)2.488644
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)2.481415
P00918Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA2760;Homo sapiens (Human)2.338456
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)2.28847
P48736Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) ...PI3/PI4-kinase familyPIK3CG5294;Homo sapiens (Human)2.257918
P29274Adenosine receptor A2aG-protein coupled receptor 1 familyADORA2A135;Homo sapiens (Human)2.175789
P42345Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein ...PI3/PI4-kinase familyMTOR2475;Homo sapiens (Human)2.1535810
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)2.1365511
O00329Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) ...PI3/PI4-kinase familyPIK3CD5293;Homo sapiens (Human)2.0991112
P0DMS8Adenosine receptor A3G-protein coupled receptor 1 familyADORA3140;Homo sapiens (Human)2.0241413
P30542Adenosine receptor A1G-protein coupled receptor 1 familyADORA1134;Homo sapiens (Human)1.9781914
Q13547Histone deacetylase 1 (HD1) (EC 3.5.1.98)Histone deacetylase family, HD type 1 subfamilyHDAC13065;Homo sapiens (Human)1.9772115
Q8NER1Transient receptor potential cation channel subfamily V member 1 (TrpV1) ...Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamilyTRPV17442;Homo sapiens (Human)1.8786316
P42336Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) ...PI3/PI4-kinase familyPIK3CA5290;Homo sapiens (Human)1.8764317
P41594Metabotropic glutamate receptor 5 (mGluR5)G-protein coupled receptor 3 familyGRM52915;Homo sapiens (Human)1.8611118
P23141Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) ...Type-B carboxylesterase/lipase familyCES11066;Homo sapiens (Human)1.8447619
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.7902520
P52732Kinesin-like protein KIF11 (Kinesin-like protein 1) (Kinesin-like spindle protein HKSP) ...TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, BimC subfamilyKIF113832;Homo sapiens (Human)1.7359621
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)1.6838722
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)1.657223
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.6567824
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)1.629125
P283355-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) ...G-protein coupled receptor 1 familyHTR2C3358;Homo sapiens (Human)1.6046526
Q16790Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA9768;Homo sapiens (Human)1.5917827
Q99705Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein ...G-protein coupled receptor 1 familyMCHR12847;Homo sapiens (Human)1.5778328
Q07343cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.53) (DPDE4) (PDE32)Cyclic nucleotide phosphodiesterase family, PDE4 subfamilyPDE4B5142;Homo sapiens (Human)1.483829
P78527DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC ...PI3/PI4-kinase familyPRKDC5591;Homo sapiens (Human)1.4636730
P11511Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen ...Cytochrome P450 familyCYP19A11588;Homo sapiens (Human)1.4478931
P00915Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA1759;Homo sapiens (Human)1.4091432
P15538Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid ...Cytochrome P450 familyCYP11B11584;Homo sapiens (Human)1.3748833
P04150Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member ...Nuclear hormone receptor family, NR3 subfamilyNR3C12908;Homo sapiens (Human)1.3690734
O43683Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)Protein kinase superfamily, Ser/Thr protein kinase family, BUB1 subfamilyBUB1699;Homo sapiens (Human)1.3424435
P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR17046;Homo sapiens (Human)1.333836
O76074cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)Cyclic nucleotide phosphodiesterase familyPDE5A8654;Homo sapiens (Human)1.3256237
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.3220138
P34972Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)G-protein coupled receptor 1 familyCNR21269;Homo sapiens (Human)1.3193939
P25103Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1)G-protein coupled receptor 1 familyTACR16869;Homo sapiens (Human)1.3150640
O43570Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA12771;Homo sapiens (Human)1.3095341
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.2768242
Q02127Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase)Dihydroorotate dehydrogenase family, Type 2 subfamilyDHODH1723;Homo sapiens (Human)1.2619143
P00742Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved ...Peptidase S1 familyF102159;Homo sapiens (Human)1.2508244
P41597C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) ...G-protein coupled receptor 1 familyCCR2729230;Homo sapiens (Human)1.2486745
P00374Dihydrofolate reductase (EC 1.5.1.3)Dihydrofolate reductase familyDHFR1719;Homo sapiens (Human)1.2447446
P282225-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (S12) (Serotonin 1D beta receptor) ...G-protein coupled receptor 1 familyHTR1B3351;Homo sapiens (Human)1.2075847
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.2055148
Q15759Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK115600;Homo sapiens (Human)1.1987549
P10275Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C ...Nuclear hormone receptor family, NR3 subfamilyAR367;Homo sapiens (Human)1.1964850

[3] CHEMBL388978

Original SMILES:
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4

Prepared SMILES:
CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O

P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)3.5165Known
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)3.45142Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)3.43844Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)3.37304Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)3.32Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)3.26216Known
Q7KZI7Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK22011;Homo sapiens (Human)3.25782Known
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)3.18643Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)3.16842Known
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)3.10935Known
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)3.08997Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)3.04188Known
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)2.96332Known
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)2.94966Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)2.92659Known
Q16512Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN15585;Homo sapiens (Human)2.92548Known
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)2.9234Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)2.91334Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)2.90192Known
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)2.89594Known
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2A815;Homo sapiens (Human)2.87371Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)2.85672Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.85146Known
Q13557Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2D817;Homo sapiens (Human)2.85145Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)2.8083Known
P27448MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK34140;Homo sapiens (Human)2.80263Known
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)2.79389Known
Q8WTQ7Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK7131890;Homo sapiens (Human)2.75889Known
P05771Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCB5579;Homo sapiens (Human)2.7488Known
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)2.74511Known
Q16816Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG15260;Homo sapiens (Human)2.74184Known
Q9NWT8Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, ...Mitochondrion-specific ribosomal protein mS38 familyAURKAIP154998;Homo sapiens (Human)2.717011
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)2.69143Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)2.68047Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)2.65618Known
O94768Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17B9262;Homo sapiens (Human)2.64477Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)2.63679Known
P41597C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) ...G-protein coupled receptor 1 familyCCR2729230;Homo sapiens (Human)2.615412
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)2.61286Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)2.60884Known
Q15139Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD15587;Homo sapiens (Human)2.59255Known
Q9P0L2Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK14139;Homo sapiens (Human)2.57926Known
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)2.57773Known
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)2.5735Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)2.571Known
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)2.55245Known
Q13554Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2B816;Homo sapiens (Human)2.54808Known
O00311Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamilyCDC78317;Homo sapiens (Human)2.526643
Q13627Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1A1859;Homo sapiens (Human)2.52423Known
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)2.52193Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)2.52098Known
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)2.51838Known
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)2.50386Known
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)2.48529Known
O00141Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1)Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK16446;Homo sapiens (Human)2.47327Known
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)2.47244Known
Q99683Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K54217;Homo sapiens (Human)2.45776Known
Q15835Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK16011;Homo sapiens (Human)2.45013Known
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)2.44654Known
Q00534Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK61021;Homo sapiens (Human)2.44245Known
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)2.44181Known
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)2.42646Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)2.42542Known
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)2.41244Known
Q15759Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK115600;Homo sapiens (Human)2.411714
Q9NRM7Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS226524;Homo sapiens (Human)2.40524Known
Q96SB4SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK16732;Homo sapiens (Human)2.3893Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)2.38662Known
Q9P286Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK557144;Homo sapiens (Human)2.38262Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)2.37624Known
Q02156Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCE5581;Homo sapiens (Human)2.36032Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)2.35521Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)2.34579Known
Q00537Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK175128;Homo sapiens (Human)2.33596Known
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)2.33436Known
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)2.33158Known
Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK18737;Homo sapiens (Human)2.331155
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)2.32265Known
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)2.32213Known
P42680Tyrosine-protein kinase Tec (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTEC7006;Homo sapiens (Human)2.32209Known
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)2.3087Known
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)2.29576Known
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)2.2817Known
Q99755Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC ...PIP5K1A8394;Homo sapiens (Human)2.27782Known
P49137MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMAPKAPK29261;Homo sapiens (Human)2.27644Known
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)2.27243Known
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)2.27139Known
P51817cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKX5613;Homo sapiens (Human)2.27013Known
Q02779Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K104294;Homo sapiens (Human)2.26427Known
Q9UEE5Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17A9263;Homo sapiens (Human)2.26376Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)2.25314Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)2.25054Known
P45985Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K46416;Homo sapiens (Human)2.24898Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)2.24876Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)2.24733Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)2.24452Known
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)2.24029Known
P78356Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2B8396;Homo sapiens (Human)2.23844Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)2.23744Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)2.22869Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)2.2267Known
Q9Y2K2Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK323387;Homo sapiens (Human)2.22628Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)2.21908Known
P04049RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyRAF15894;Homo sapiens (Human)2.21796Known
P43403Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) ...Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilyZAP707535;Homo sapiens (Human)2.2156Known
Q8IWQ3Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK29024;Homo sapiens (Human)2.21493Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)2.21422Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)2.20408Known
Q6ZN16Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K15389840;Homo sapiens (Human)2.20263Known
Q96L34MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK457787;Homo sapiens (Human)2.1995Known
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)2.18629Known
Q13490Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of ...IAP familyBIRC2329;Homo sapiens (Human)2.184726
Q07002Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK185129;Homo sapiens (Human)2.18442Known
P24723Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCH5583;Homo sapiens (Human)2.18328Known
P53355Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK11612;Homo sapiens (Human)2.18059Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)2.17936Known
Q04759Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCQ5588;Homo sapiens (Human)2.17721Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)2.17639Known
Q05655Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCD5580;Homo sapiens (Human)2.16692Known
P11309Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM15292;Homo sapiens (Human)2.16639Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)2.1607Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)2.15883Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)2.15852Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)2.14792Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)2.14374Known
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)2.13941Known
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)2.13659Known
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)2.1351Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)2.13077Known
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)2.12559Known
Q13555Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2G818;Homo sapiens (Human)2.11357Known
O15111Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyCHUK1147;Homo sapiens (Human)2.11182Known
O76039Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL56792;Homo sapiens (Human)2.11019Known
Q8TD08Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15225689;Homo sapiens (Human)2.11011Known
Q96BR1Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK3100533105;23678;Homo sapiens (Human)2.10321Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)2.10221Known
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)2.10174Known
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)2.09661Known
Q9NQU5Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK6106821730;56924;Homo sapiens (Human)2.09315Known
O15264Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK135603;Homo sapiens (Human)2.09239Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)2.09112Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)2.0902Known
P05129Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCG5582;Homo sapiens (Human)2.08907Known
Q13153Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK15058;Homo sapiens (Human)2.08648Known
O14730Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK38780;Homo sapiens (Human)2.07414Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)2.07413Known
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)2.07039Known
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)2.06891Known
Q9BRS2Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK183732;Homo sapiens (Human)2.06836Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)2.0617Known
O14936Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; ...CASK8573;Homo sapiens (Human)2.05512Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)2.05366Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)2.05231Known
O75914Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK35063;Homo sapiens (Human)2.05108Known
P34972Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)G-protein coupled receptor 1 familyCNR21269;Homo sapiens (Human)2.046737
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)2.02351Known
Q9Y463Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1B9149;Homo sapiens (Human)2.01798Known
Q13237cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG25593;Homo sapiens (Human)2.00934Known
Q9NYY3Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK210769;Homo sapiens (Human)2.00417Known
Q9UIK4Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK223604;Homo sapiens (Human)1.99892Known
P09874Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like ...PARP1142;Homo sapiens (Human)1.998668
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)1.9923Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.98348Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)1.97888Known
Q00532Cyclin-dependent kinase-like 1 (EC 2.7.11.22) (Protein kinase p42 KKIALRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL18814;Homo sapiens (Human)1.9748Known
Q99558Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K149020;Homo sapiens (Human)1.96108Known
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)1.96068Known
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)1.95597Known
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)1.95538Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)1.95313Known
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.9481Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)1.94284Known
Q6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein ...Protein kinase superfamily, Ser/Thr protein kinase familyDSTYK25778;Homo sapiens (Human)1.93567Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)1.93558Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)1.93028Known
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)1.92775Known
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.92743Known
Q8TDC3Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK184446;Homo sapiens (Human)1.92698Known
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.92658Known
Q86YV6Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4340156;Homo sapiens (Human)1.9244Known
P22694cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACB5567;Homo sapiens (Human)1.92061Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)1.91523Known
Q13177Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK25062;Homo sapiens (Human)1.91435Known
Q15046Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)Class-II aminoacyl-tRNA synthetase familyKARS3735;Homo sapiens (Human)1.91308Known
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)1.91024Known
P17252Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCA5578;Homo sapiens (Human)1.90972Known
Q5VT25Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPA8476;Homo sapiens (Human)1.90562Known
P57078Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK4Homo sapiens (Human)1.89615Known
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)1.88641Known
Q9H1R3Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK285366;Homo sapiens (Human)1.87713Known
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.87236Known
Q14012Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK18536;Homo sapiens (Human)1.87117Known
Q00526Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK31018;Homo sapiens (Human)1.86379Known
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)1.85694Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)1.85607Known
P78362SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK26733;Homo sapiens (Human)1.85161Known
Q09013Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyDMPK1760;Homo sapiens (Human)1.84553Known
P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR17046;Homo sapiens (Human)1.84443Known
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.84279Known
Q9BX84Transient receptor potential cation channel subfamily M member 6 (EC ...Protein kinase superfamily, Alpha-type protein kinase family, ALPK subfamily; Transient ...TRPM6140803;Homo sapiens (Human)1.840119
Q52WX2Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySBK1388228;Homo sapiens (Human)1.8378Known
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)1.83039Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)1.83039Known
P546465'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA25563;Homo sapiens (Human)1.82772Known
P14616Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSRR3645;Homo sapiens (Human)1.81962Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)1.80551Known
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.80542Known
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)1.79887Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)1.7973Known
P80370Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen ...DLK18788;Homo sapiens (Human)1.7934310
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)1.7913Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)1.79112Known
O95835Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS19113;Homo sapiens (Human)1.78982Known
Q9BWU1Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1923097;Homo sapiens (Human)1.7743Known
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)1.77375Known
Q8NFD2Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyANKK1255239;Homo sapiens (Human)1.77334Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)1.76623Known
O94921Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK145218;Homo sapiens (Human)1.76458Known
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)1.76344Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)1.75885Known
O75460Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyERN12081;Homo sapiens (Human)1.75403Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.75366Known
Q13976cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG15592;Homo sapiens (Human)1.74683Known
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)1.73309Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)1.73295Known
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)1.72343Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.72288Known
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)1.7176Known
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)1.70823Known
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)1.69854Known
Q9C098Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK385443;Homo sapiens (Human)1.68807Known
P78527DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC ...PI3/PI4-kinase familyPRKDC5591;Homo sapiens (Human)1.6797711
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.67668Known
P0C264Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family ...Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamilySBK3100130827;Homo sapiens (Human)1.67469Known
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)1.66796Known
Q15910Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.43) (ENX-1) (Enhancer of zeste homolog ...Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, EZ subfamilyEZH22146;Homo sapiens (Human)1.6663412
Q96D53Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase ...Protein kinase superfamily, ADCK protein kinase familyCOQ8B79934;Homo sapiens (Human)1.6663313
Q15750TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Mitogen-activated protein kinase ...TAB110454;Homo sapiens (Human)1.66559Known
Q15831Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamilySTK116794;Homo sapiens (Human)1.66097Known
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)1.65622Known
Q13489Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) ...IAP familyBIRC3330;Homo sapiens (Human)1.6517614
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.64735Known
Q86UE8Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase ...Protein kinase superfamily, Ser/Thr protein kinase familyTLK211011;Homo sapiens (Human)1.64707Known
Q9BXA7Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK1B83942;Homo sapiens (Human)1.6464Known
O00506Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2510494;Homo sapiens (Human)1.64578Known
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)1.63725Known
Q92630Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK28445;Homo sapiens (Human)1.63181Known
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)1.62682Known
Q9UKI8Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyTLK19874;Homo sapiens (Human)1.62437Known
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)1.6197Known
Q9Y2H9Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)Protein kinase superfamily, AGC Ser/Thr protein kinase familyMAST122983;Homo sapiens (Human)1.6185Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)1.61803Known
Q9Y6E0Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK248428;Homo sapiens (Human)1.61431Known
P53778Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK126300;Homo sapiens (Human)1.60958Known
Q9NY57Serine/threonine-protein kinase 32B (EC 2.7.11.1) (Yet another novel kinase 2)Protein kinase superfamily, Ser/Thr protein kinase familySTK32B55351;Homo sapiens (Human)1.60659Known
P52564Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K65608;Homo sapiens (Human)1.60527Known
Q00535Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK51020;Homo sapiens (Human)1.60446Known
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)1.60261Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)1.59113Known
Q9NRH2SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familySNRK54861;Homo sapiens (Human)1.59047Known
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.57742Known
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.57512Known
P42336Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) ...PI3/PI4-kinase familyPIK3CA5290;Homo sapiens (Human)1.5692Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)1.56482Known
Q96NX5Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1G57172;Homo sapiens (Human)1.55185Known
P0DMS8Adenosine receptor A3G-protein coupled receptor 1 familyADORA3140;Homo sapiens (Human)1.5466815
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)1.54544Known
O14733Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K75609;Homo sapiens (Human)1.5452Known
P00734Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide ...Peptidase S1 familyF22147;Homo sapiens (Human)1.5302116
P98170E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein ...IAP familyXIAP331;Homo sapiens (Human)1.5266217
P42345Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein ...PI3/PI4-kinase familyMTOR2475;Homo sapiens (Human)1.5168118
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.51643Known
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)1.50458Known
P15538Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid ...Cytochrome P450 familyCYP11B11584;Homo sapiens (Human)1.5037519
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)1.50172Known
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)1.49569Known
Q13523Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familyPRPF4B8899;Homo sapiens (Human)1.49318Known
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)1.48499Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)1.48033Known
P06400Retinoblastoma-associated protein (p105-Rb) (pRb) (Rb) (pp110)Retinoblastoma protein (RB) familyRB15925;Homo sapiens (Human)1.47877Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)1.47695Known
P504065-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)G-protein coupled receptor 1 familyHTR63362;Homo sapiens (Human)1.4728320
O43172U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP ...PRPF49128;Homo sapiens (Human)1.4611421
P48729Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A11452;Homo sapiens (Human)1.45337Known
Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)1.453Known
P36896Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR1B91;Homo sapiens (Human)1.45286Known
P22612cAMP-dependent protein kinase catalytic subunit gamma (PKA C-gamma) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACG5568;Homo sapiens (Human)1.45283Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)1.44906Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.44692Known
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)1.44046Known
Q8NEV4Myosin-IIIa (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3A53904;Homo sapiens (Human)1.43452Known
P48736Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) ...PI3/PI4-kinase familyPIK3CG5294;Homo sapiens (Human)1.43229Known
O43781Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1) (Regulatory erythroid kinase) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK38444;Homo sapiens (Human)1.42522
Q9H4B4Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK31263;Homo sapiens (Human)1.41426Known
O14920Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKB3551;Homo sapiens (Human)1.41196Known
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)1.40972Known
Q9UBE8Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...NLK51701;Homo sapiens (Human)1.39746Known
P31749RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT1207;Homo sapiens (Human)1.39445Known
P30291Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE17465;Homo sapiens (Human)1.39385Known
Q8IW41MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMAPKAPK58550;Homo sapiens (Human)1.39242Known
Q15208Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySTK3811329;Homo sapiens (Human)1.38873Known
Q9BQI3Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK127102;Homo sapiens (Human)1.379623
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)1.37889Known
O14578Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)Protein kinase superfamily, AGC Ser/Thr protein kinase familyCIT11113;Homo sapiens (Human)1.37755Known
Q96PF2Testis-specific serine/threonine-protein kinase 2 (TSK-2) (TSK2) (TSSK-2) (Testis-specific kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK223617;Homo sapiens (Human)1.3741824
P27986Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K ...PI3K p85 subunit familyPIK3R15295;Homo sapiens (Human)1.3656725
Q01538Myelin transcription factor 1 (MyT1) (Myelin transcription factor I) (MyTI) ...MYT1 familyMYT14661;Homo sapiens (Human)1.3557226
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)1.34856Known
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.34833Known
O95382Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K69064;Homo sapiens (Human)1.34793Known
Q13164Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK75598;Homo sapiens (Human)1.34576Known
P49674Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1E102800317;1454;Homo sapiens (Human)1.34442Known
P41240Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyCSK1445;Homo sapiens (Human)1.34432Known
Q9Y2H1Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySTK38L23012;Homo sapiens (Human)1.34046Known
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.31252Known
O15146Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase familyMUSK4593;Homo sapiens (Human)1.31215Known
P19525Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK25610;Homo sapiens (Human)1.31188Known
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)1.30939Known
Q86UX6Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (Yet another novel kinase ...Protein kinase superfamily, Ser/Thr protein kinase familySTK32C282974;Homo sapiens (Human)1.30754Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.29953Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.29399Known
Q9HC98Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK610783;Homo sapiens (Human)1.2927127
Q92772Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL28999;Homo sapiens (Human)1.28187Known
Q9P289Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2651765;Homo sapiens (Human)1.27797Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)1.27761Known
P28482Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15594;Homo sapiens (Human)1.27647Known
Q9UQ88Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK11A728642;Homo sapiens (Human)1.2747428
P41143Delta-type opioid receptor (D-OR-1) (DOR-1)G-protein coupled receptor 1 familyOPRD14985;Homo sapiens (Human)1.2703329
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.25004Known
Q96Q40Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1565061;Homo sapiens (Human)1.24713Known
P49116Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear ...Nuclear hormone receptor family, NR2 subfamilyNR2C27182;Homo sapiens (Human)1.2463830
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.2460131
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)1.22966Known
Q9BUB5MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK18569;Homo sapiens (Human)1.22856Known
Q8TBX8Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2C79837;Homo sapiens (Human)1.2246732
P57058Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyHUNK30811;Homo sapiens (Human)1.22386Known
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)1.2189633
Q15375Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA72045;Homo sapiens (Human)1.21317Known
Q9NR20Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK48798;Homo sapiens (Human)1.2085634
P34947G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK52869;Homo sapiens (Human)1.2085435
Q9Y5Y9Sodium channel protein type 10 subunit alpha (Peripheral nerve sodium ...Sodium channel (TC 1.A.1.10) family, Nav1.8/SCN10A subfamilySCN10A6336;Homo sapiens (Human)1.1973736
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)1.19494Known
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.194Known
O00750Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 ...PI3/PI4-kinase familyPIK3C2B5287;Homo sapiens (Human)1.1887137
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)1.18205Known
P283355-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) ...G-protein coupled receptor 1 familyHTR2C3358;Homo sapiens (Human)1.1806538
P31751RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT2208;Homo sapiens (Human)1.17568Known
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)1.173439
Q99640Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyPKMYT19088;Homo sapiens (Human)1.1733540
P10398Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyARAF369;Homo sapiens (Human)1.1729241
Q9UEW8STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK3927347;Homo sapiens (Human)1.17279Known
P37023Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVRL194;Homo sapiens (Human)1.1713Known
Q8IY84Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyNIM1K167359;Homo sapiens (Human)1.16768Known
Q16566Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK4814;Homo sapiens (Human)1.16745Known
O00329Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) ...PI3/PI4-kinase familyPIK3CD5293;Homo sapiens (Human)1.1672442
P49286Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)G-protein coupled receptor 1 familyMTNR1B4544;Homo sapiens (Human)1.1620343
P41743Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCI5584;Homo sapiens (Human)1.16104Known
P29371Neuromedin-K receptor (NKR) (NK-3 receptor) (NK-3R) (Neurokinin B receptor) (Tachykinin ...G-protein coupled receptor 1 familyTACR36870;Homo sapiens (Human)1.1558444
P53350Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK15347;Homo sapiens (Human)1.14228Known
P21127Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK11B984;Homo sapiens (Human)1.1366745
Q8WU08Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySTK32A202374;Homo sapiens (Human)1.13504Known
Q8NER1Transient receptor potential cation channel subfamily V member 1 (TrpV1) ...Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamilyTRPV17442;Homo sapiens (Human)1.1264346
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)1.1173147
Q8TD19Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK991754;Homo sapiens (Human)1.10981Known
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)1.10901Known
P37173TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR27048;Homo sapiens (Human)1.1077648
P49761Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK31198;Homo sapiens (Human)1.10183Known
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)1.1011249
Q15569Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyTESK17016;Homo sapiens (Human)1.09846Known
P11229Muscarinic acetylcholine receptor M1G-protein coupled receptor 1 family, Muscarinic acetylcholine receptor subfamily, CHRM1 ...CHRM11128;Homo sapiens (Human)1.0980250
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)1.0964Known
O75747Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma (PI3K-C2-gamma) (PtdIns-3-kinase C2 ...PI3/PI4-kinase familyPIK3C2G5288;Homo sapiens (Human)1.09347Known
Q13233Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K14214;Homo sapiens (Human)1.08971Known
Q59H18Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase ...TNNI3K100526835;51086;Homo sapiens (Human)1.08568Known
P78368Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G21455;Homo sapiens (Human)1.08431Known
P42679Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic ...Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyMATK4145;Homo sapiens (Human)1.08028Known
Q8WXR4Myosin-IIIb (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3B140469;Homo sapiens (Human)1.07854Known
P36894Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1A657;Homo sapiens (Human)1.04383Known
P48730Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein ...Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1D1453;Homo sapiens (Human)1.03951Known
Q8N568Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK2166614;Homo sapiens (Human)1.03224Known
Q8NG66Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK1179858;Homo sapiens (Human)1.02733Known
Q9Y5S2Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPB9578;Homo sapiens (Human)1.00357Known
P20794Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyMAK4117;Homo sapiens (Human)1.00152Known
P54756Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA52044;Homo sapiens (Human)0.980192Known
Q9BVS4Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK255781;Homo sapiens (Human)0.974281Known
P53671LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK23985;Homo sapiens (Human)0.962138Known
Q9Y243RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT310000;Homo sapiens (Human)0.958426Known
Q6DT37Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPG55561;Homo sapiens (Human)0.948141Known
P51955Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK24751;Homo sapiens (Human)0.936435Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)0.918909Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)0.916893Known
Q9UBF8Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) ...PI3/PI4-kinase family, Type III PI4K subfamilyPI4KB5298;Homo sapiens (Human)0.913031Known
Q8TDX7Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK7140609;Homo sapiens (Human)0.909295Known
O15075Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK19201;Homo sapiens (Human)0.896682Known
P54764Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA42043;Homo sapiens (Human)0.869362Known
Q13705Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2B93;Homo sapiens (Human)0.868313Known
Q16659Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK65597;Homo sapiens (Human)0.864661Known
Q13873Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR2659;Homo sapiens (Human)0.857896Known
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)0.839082Known
Q9HCP0Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G153944;Homo sapiens (Human)0.830885Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)0.798916Known
Q96PY6Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK14750;Homo sapiens (Human)0.78618Known
Q9Y6R4Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K44216;Homo sapiens (Human)0.783115Known
Q8N752Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A1L122011;Homo sapiens (Human)0.779957Known
Q8IVW4Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine-protein kinase NKIAMRE)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL351265;Homo sapiens (Human)0.717345Known
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)0.709342Known
P27037Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2A92;Homo sapiens (Human)0.701274Known
O60331Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC ...PIP5K1C23396;Homo sapiens (Human)0.690692Known
P29323Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB22048;Homo sapiens (Human)0.66702Known
P27361Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK35595;Homo sapiens (Human)0.665679Known
Q6P3R8Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK5341676;Homo sapiens (Human)0.654568Known
O95747Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyOXSR19943;Homo sapiens (Human)0.64994Known
Q05513Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCZ5590;Homo sapiens (Human)0.479458Known
O14746Telomerase reverse transcriptase (EC 2.7.7.49) (HEST2) (Telomerase catalytic subunit) (Telomerase-associated ...Reverse transcriptase family, Telomerase subfamilyTERT7015;Homo sapiens (Human)0.473849Known
Q9NRP7Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)Protein kinase superfamily, Ser/Thr protein kinase familySTK3627148;Homo sapiens (Human)0.455902Known

[4] CHEMBL603469

Original SMILES:
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O

Prepared SMILES:
OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O

Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)3.58997Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)3.5165Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)3.43844Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)3.37304Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)3.32Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)3.26216Known
Q7KZI7Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK22011;Homo sapiens (Human)3.25782Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)3.19209Known
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)3.18643Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)3.16842Known
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)3.11695Known
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)2.96332Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)2.92658Known
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)2.92339Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)2.91334Known
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2A815;Homo sapiens (Human)2.89923Known
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)2.89594Known
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)2.87559Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)2.85672Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.85145Known
Q13557Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2D817;Homo sapiens (Human)2.85145Known
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)2.84268Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)2.8083Known
P27448MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK34140;Homo sapiens (Human)2.80263Known
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)2.79897Known
Q15759Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK115600;Homo sapiens (Human)2.788771
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)2.78673Known
Q8WTQ7Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK7131890;Homo sapiens (Human)2.75889Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)2.7559Known
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)2.75249Known
P05771Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCB5579;Homo sapiens (Human)2.74882
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)2.74511Known
Q16816Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG15260;Homo sapiens (Human)2.74184Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)2.68047Known
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)2.67466Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)2.65618Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)2.64823Known
O94768Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17B9262;Homo sapiens (Human)2.64477Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)2.63679Known
Q16512Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN15585;Homo sapiens (Human)2.62143Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)2.61286Known
Q02779Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K104294;Homo sapiens (Human)2.6126Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)2.60884Known
Q15139Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD15587;Homo sapiens (Human)2.59255Known
Q9P0L2Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK14139;Homo sapiens (Human)2.57926Known
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)2.57353
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)2.57238Known
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)2.55245Known
Q9P286Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK557144;Homo sapiens (Human)2.54857Known
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)2.54005Known
Q9NQU5Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK6106821730;56924;Homo sapiens (Human)2.52777Known
Q13627Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1A1859;Homo sapiens (Human)2.52423Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)2.52098Known
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)2.51838Known
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)2.48529Known
Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK18737;Homo sapiens (Human)2.482484
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)2.47518Known
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)2.47244Known
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)2.46864Known
Q15835Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK16011;Homo sapiens (Human)2.45013Known
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)2.44181Known
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)2.43358Known
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)2.42646Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)2.42542Known
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)2.424815
Q9NRM7Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS226524;Homo sapiens (Human)2.40524Known
Q96SB4SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK16732;Homo sapiens (Human)2.3893Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)2.36691Known
Q02156Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCE5581;Homo sapiens (Human)2.36032Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)2.35522Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)2.34579Known
Q00537Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK175128;Homo sapiens (Human)2.33596Known
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)2.33436Known
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)2.33158Known
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)2.32265Known
P42680Tyrosine-protein kinase Tec (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTEC7006;Homo sapiens (Human)2.32209Known
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)2.3087Known
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)2.29576Known
Q9Y463Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1B9149;Homo sapiens (Human)2.2831Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)2.28033Known
Q99755Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC ...PIP5K1A8394;Homo sapiens (Human)2.27783Known
P49137MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMAPKAPK29261;Homo sapiens (Human)2.27645Known
Q99683Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K54217;Homo sapiens (Human)2.27435Known
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)2.27243Known
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)2.27139Known
Q9UEE5Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17A9263;Homo sapiens (Human)2.26376Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)2.25314Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)2.25054Known
P45985Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K46416;Homo sapiens (Human)2.24898Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)2.24733Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)2.24452Known
Q9NWT8Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, ...Mitochondrion-specific ribosomal protein mS38 familyAURKAIP154998;Homo sapiens (Human)2.242026
P78356Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2B8396;Homo sapiens (Human)2.23844Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)2.23744Known
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)2.2347Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)2.22869Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)2.2267Known
Q9Y2K2Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK323387;Homo sapiens (Human)2.22628Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)2.21908Known
Q8IWQ3Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK29024;Homo sapiens (Human)2.21493Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)2.21422Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)2.21176Known
Q8TD08Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15225689;Homo sapiens (Human)2.20402Known
Q6ZN16Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K15389840;Homo sapiens (Human)2.20263Known
P31749RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT1207;Homo sapiens (Human)2.18584Known
P24723Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCH5583;Homo sapiens (Human)2.18328Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)2.18323Known
P53355Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK11612;Homo sapiens (Human)2.18059Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)2.17936Known
Q04759Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCQ5588;Homo sapiens (Human)2.17721Known
Q9NYY3Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK210769;Homo sapiens (Human)2.17448Known
Q05655Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCD5580;Homo sapiens (Human)2.16692Known
P11309Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM15292;Homo sapiens (Human)2.16639Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)2.15883Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)2.15852Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)2.15146Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)2.14791Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)2.14374Known
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)2.13941Known
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)2.13659Known
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)2.1351Known
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)2.13148Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)2.13077Known
Q96L34MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK457787;Homo sapiens (Human)2.13006Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)2.12041Known
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)2.11372Known
Q13555Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2G818;Homo sapiens (Human)2.11357Known
O15111Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyCHUK1147;Homo sapiens (Human)2.11182Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)2.11034Known
O76039Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL56792;Homo sapiens (Human)2.11019Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)2.10539Known
Q96BR1Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK3100533105;23678;Homo sapiens (Human)2.10321Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)2.10221Known
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)2.10174Known
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)2.09661Known
O15264Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK135603;Homo sapiens (Human)2.09239Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)2.09112Known
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)2.08944Known
P43403Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) ...Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilyZAP707535;Homo sapiens (Human)2.08931Known
P05129Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCG5582;Homo sapiens (Human)2.089077
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)2.07883Known
Q13554Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2B816;Homo sapiens (Human)2.07785Known
P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR17046;Homo sapiens (Human)2.07655Known
O14730Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK38780;Homo sapiens (Human)2.07414Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)2.07413Known
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)2.07039Known
Q9BRS2Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK183732;Homo sapiens (Human)2.06836Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)2.05366Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)2.05231Known
O75914Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK35063;Homo sapiens (Human)2.05108Known
Q13153Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK15058;Homo sapiens (Human)2.03808Known
Q13177Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK25062;Homo sapiens (Human)2.0255Known
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)2.02351Known
Q13237cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG25593;Homo sapiens (Human)2.00934Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)2.00726Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)2.00195Known
Q9UIK4Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK223604;Homo sapiens (Human)1.99892Known
P51817cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKX5613;Homo sapiens (Human)1.99514Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)1.9923Known
Q9Y2H9Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)Protein kinase superfamily, AGC Ser/Thr protein kinase familyMAST122983;Homo sapiens (Human)1.99135Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.98348Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)1.97888Known
Q00532Cyclin-dependent kinase-like 1 (EC 2.7.11.22) (Protein kinase p42 KKIALRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL18814;Homo sapiens (Human)1.9748Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)1.97381Known
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)1.96218Known
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)1.96068Known
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)1.95597Known
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)1.95537Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)1.95313Known
P34972Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)G-protein coupled receptor 1 familyCNR21269;Homo sapiens (Human)1.950288
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)1.946519
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)1.94284Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)1.93558Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)1.93028Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.92987Known
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)1.92775Known
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.92744Known
Q8TDC3Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK184446;Homo sapiens (Human)1.92698Known
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.92658Known
Q86YV6Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4340156;Homo sapiens (Human)1.9244Known
P22694cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACB5567;Homo sapiens (Human)1.92061Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)1.91523Known
P53671LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK23985;Homo sapiens (Human)1.9136410
P17252Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCA5578;Homo sapiens (Human)1.90972Known
Q14012Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK18536;Homo sapiens (Human)1.9077Known
P57078Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK4Homo sapiens (Human)1.89615Known
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)1.89492Known
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)1.89101Known
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)1.88641Known
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)1.88298Known
Q9H1R3Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK285366;Homo sapiens (Human)1.87713Known
Q00526Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK31018;Homo sapiens (Human)1.86379Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)1.85607Known
P78362SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK26733;Homo sapiens (Human)1.85161Known
Q09013Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyDMPK1760;Homo sapiens (Human)1.84553Known
O14936Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; ...CASK8573;Homo sapiens (Human)1.84384Known
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.84279Known
Q52WX2Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySBK1388228;Homo sapiens (Human)1.8378Known
Q07002Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK185129;Homo sapiens (Human)1.8349311
P546465'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA25563;Homo sapiens (Human)1.82772Known
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.81129Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)1.80551Known
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.80542Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)1.7973Known
O14578Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)Protein kinase superfamily, AGC Ser/Thr protein kinase familyCIT11113;Homo sapiens (Human)1.7962Known
O00311Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamilyCDC78317;Homo sapiens (Human)1.793812
P80370Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen ...DLK18788;Homo sapiens (Human)1.79343Known
O95835Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS19113;Homo sapiens (Human)1.78982Known
P36896Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR1B91;Homo sapiens (Human)1.78108Known
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)1.77838Known
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)1.77375Known
Q8NFD2Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyANKK1255239;Homo sapiens (Human)1.77334Known
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)1.7725Known
Q6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein ...Protein kinase superfamily, Ser/Thr protein kinase familyDSTYK25778;Homo sapiens (Human)1.77128Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)1.76623Known
O94921Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK145218;Homo sapiens (Human)1.76458Known
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)1.76344Known
O75460Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyERN12081;Homo sapiens (Human)1.75403Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.75366Known
Q13976cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG15592;Homo sapiens (Human)1.74683Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)1.73295Known
Q59H18Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase ...TNNI3K100526835;51086;Homo sapiens (Human)1.72401Known
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)1.72343Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.72288Known
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)1.7176Known
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)1.7165Known
Q9BWU1Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1923097;Homo sapiens (Human)1.7113513
Q15375Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA72045;Homo sapiens (Human)1.70512Known
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)1.69854Known
P11229Muscarinic acetylcholine receptor M1G-protein coupled receptor 1 family, Muscarinic acetylcholine receptor subfamily, CHRM1 ...CHRM11128;Homo sapiens (Human)1.6935414
Q9C098Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK385443;Homo sapiens (Human)1.68807Known
Q9BXA7Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK1B83942;Homo sapiens (Human)1.68683Known
P0C264Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family ...Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamilySBK3100130827;Homo sapiens (Human)1.67469Known
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)1.66796Known
Q15831Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamilySTK116794;Homo sapiens (Human)1.66097Known
O75747Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma (PI3K-C2-gamma) (PtdIns-3-kinase C2 ...PI3/PI4-kinase familyPIK3C2G5288;Homo sapiens (Human)1.65904Known
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)1.65622Known
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.64735Known
Q86UE8Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase ...Protein kinase superfamily, Ser/Thr protein kinase familyTLK211011;Homo sapiens (Human)1.64707Known
O00506Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2510494;Homo sapiens (Human)1.64578Known
P78527DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC ...PI3/PI4-kinase familyPRKDC5591;Homo sapiens (Human)1.6394715
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)1.63725Known
Q92630Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK28445;Homo sapiens (Human)1.63181Known
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)1.6265316
Q9UKI8Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyTLK19874;Homo sapiens (Human)1.62437Known
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.62284Known
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)1.6197Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)1.60976Known
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)1.60963Known
P53778Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK126300;Homo sapiens (Human)1.60958Known
P52564Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K65608;Homo sapiens (Human)1.60527Known
Q00535Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK51020;Homo sapiens (Human)1.60446Known
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)1.60424Known
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)1.60261Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)1.59113Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)1.59112Known
P14616Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSRR3645;Homo sapiens (Human)1.58448Known
Q5VT25Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPA8476;Homo sapiens (Human)1.58062Known
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.57512Known
P42336Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) ...PI3/PI4-kinase familyPIK3CA5290;Homo sapiens (Human)1.5692Known
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)1.55998Known
P04049RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyRAF15894;Homo sapiens (Human)1.5592217
Q96NX5Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1G57172;Homo sapiens (Human)1.55185Known
Q9UBF8Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) ...PI3/PI4-kinase family, Type III PI4K subfamilyPI4KB5298;Homo sapiens (Human)1.54954Known
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.54592Known
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)1.54563Known
O14733Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K75609;Homo sapiens (Human)1.5452Known
O43781Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1) (Regulatory erythroid kinase) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK38444;Homo sapiens (Human)1.5368818
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)1.52953Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.51643Known
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)1.49569Known
Q13523Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familyPRPF4B8899;Homo sapiens (Human)1.49319Known
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.48839Known
P20794Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyMAK4117;Homo sapiens (Human)1.48016Known
P78368Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G21455;Homo sapiens (Human)1.477619
Q9UQ88Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK11A728642;Homo sapiens (Human)1.4700320
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)1.46957Known
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.46321Known
P42345Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein ...PI3/PI4-kinase familyMTOR2475;Homo sapiens (Human)1.45751Known
P48729Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A11452;Homo sapiens (Human)1.4533721
Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)1.453Known
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)1.44733Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.44692Known
Q8NEV4Myosin-IIIa (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3A53904;Homo sapiens (Human)1.43452Known
P48736Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) ...PI3/PI4-kinase familyPIK3CG5294;Homo sapiens (Human)1.43229Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)1.42912Known
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.4278322
O14920Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKB3551;Homo sapiens (Human)1.41196Known
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)1.40972Known
O43172U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP ...PRPF49128;Homo sapiens (Human)1.40885Known
P30291Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE17465;Homo sapiens (Human)1.39385Known
Q15910Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.43) (ENX-1) (Enhancer of zeste homolog ...Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, EZ subfamilyEZH22146;Homo sapiens (Human)1.3934323
Q8IW41MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMAPKAPK58550;Homo sapiens (Human)1.39242Known
Q15208Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySTK3811329;Homo sapiens (Human)1.38873Known
Q9P289Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2651765;Homo sapiens (Human)1.3846Known
Q00534Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK61021;Homo sapiens (Human)1.3811624
P42679Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic ...Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyMATK4145;Homo sapiens (Human)1.38029Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)1.37889Known
O00141Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1)Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK16446;Homo sapiens (Human)1.3628725
Q9BX84Transient receptor potential cation channel subfamily M member 6 (EC ...Protein kinase superfamily, Alpha-type protein kinase family, ALPK subfamily; Transient ...TRPM6140803;Homo sapiens (Human)1.3556726
Q92772Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL28999;Homo sapiens (Human)1.3508Known
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.34833Known
Q13164Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK75598;Homo sapiens (Human)1.34576Known
Q9Y2H1Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySTK38L23012;Homo sapiens (Human)1.34046Known
P48730Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein ...Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1D1453;Homo sapiens (Human)1.326227
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)1.31489Known
O15146Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase familyMUSK4593;Homo sapiens (Human)1.31215Known
P19525Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK25610;Homo sapiens (Human)1.31188Known
Q9NUW8Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-)Tyrosyl-DNA phosphodiesterase familyTDP155775;Homo sapiens (Human)1.30223Known
Q9Y6E0Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK248428;Homo sapiens (Human)1.29982Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.29953Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.29399Known
Q9UBE8Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...NLK51701;Homo sapiens (Human)1.288Known
Q13233Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K14214;Homo sapiens (Human)1.28626Known
P28482Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15594;Homo sapiens (Human)1.2764728
P21127Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK11B984;Homo sapiens (Human)1.2755629
P0DMS8Adenosine receptor A3G-protein coupled receptor 1 familyADORA3140;Homo sapiens (Human)1.273830
P27986Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K ...PI3K p85 subunit familyPIK3R15295;Homo sapiens (Human)1.2737831
Q9HC98Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK610783;Homo sapiens (Human)1.2606Known
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.25004Known
Q96Q40Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1565061;Homo sapiens (Human)1.24713Known
Q9BUB5MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK18569;Homo sapiens (Human)1.22856Known
P57058Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyHUNK30811;Homo sapiens (Human)1.22386Known
Q15569Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyTESK17016;Homo sapiens (Human)1.22012Known
Q9H2K2Poly [ADP-ribose] polymerase tankyrase-2 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) ...TNKS280351;Homo sapiens (Human)1.21991Known
P49674Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1E102800317;1454;Homo sapiens (Human)1.2162532
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)1.20744Known
O00750Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 ...PI3/PI4-kinase familyPIK3C2B5287;Homo sapiens (Human)1.18871Known
P41240Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyCSK1445;Homo sapiens (Human)1.18665Known
O95382Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K69064;Homo sapiens (Human)1.18598Known
Q16566Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK4814;Homo sapiens (Human)1.18321Known
P31751RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT2208;Homo sapiens (Human)1.17568Known
Q9UEW8STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK3927347;Homo sapiens (Human)1.17279Known
O00329Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) ...PI3/PI4-kinase familyPIK3CD5293;Homo sapiens (Human)1.16724Known
P37173TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR27048;Homo sapiens (Human)1.16371Known
P41743Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCI5584;Homo sapiens (Human)1.16104Known
Q8TBX8Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2C79837;Homo sapiens (Human)1.1534833
Q96D53Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase ...Protein kinase superfamily, ADCK protein kinase familyCOQ8B79934;Homo sapiens (Human)1.1513334
P53350Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK15347;Homo sapiens (Human)1.14228Known
Q8WU08Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySTK32A202374;Homo sapiens (Human)1.13504Known
P34947G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK52869;Homo sapiens (Human)1.1323435
Q01538Myelin transcription factor 1 (MyT1) (Myelin transcription factor I) (MyTI) ...MYT1 familyMYT14661;Homo sapiens (Human)1.129336
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)1.1128737
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)1.10901Known
P49761Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK31198;Homo sapiens (Human)1.1018338
P283355-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) ...G-protein coupled receptor 1 familyHTR2C3358;Homo sapiens (Human)1.0945639
Q9NRH2SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familySNRK54861;Homo sapiens (Human)1.0913840
Q86UX6Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (Yet another novel kinase ...Protein kinase superfamily, Ser/Thr protein kinase familySTK32C282974;Homo sapiens (Human)1.08899Known
Q8WXR4Myosin-IIIb (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3B140469;Homo sapiens (Human)1.07854Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)1.07644Known
Q8NG66Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK1179858;Homo sapiens (Human)1.0633641
Q96PF2Testis-specific serine/threonine-protein kinase 2 (TSK-2) (TSK2) (TSSK-2) (Testis-specific kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK223617;Homo sapiens (Human)1.0557942
Q9NY57Serine/threonine-protein kinase 32B (EC 2.7.11.1) (Yet another novel kinase 2)Protein kinase superfamily, Ser/Thr protein kinase familySTK32B55351;Homo sapiens (Human)1.05387Known
P51955Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK24751;Homo sapiens (Human)1.0425Known
Q9BQI3Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK127102;Homo sapiens (Human)1.0386943
Q9HCP0Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G153944;Homo sapiens (Human)1.0343544
Q8N568Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK2166614;Homo sapiens (Human)1.03224Known
P29371Neuromedin-K receptor (NKR) (NK-3 receptor) (NK-3R) (Neurokinin B receptor) (Tachykinin ...G-protein coupled receptor 1 familyTACR36870;Homo sapiens (Human)1.0288145
P54753Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB32049;Homo sapiens (Human)1.0287946
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.01526Known
Q9H4B4Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK31263;Homo sapiens (Human)1.01494Known
P49116Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear ...Nuclear hormone receptor family, NR2 subfamilyNR2C27182;Homo sapiens (Human)1.0138447
P29323Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB22048;Homo sapiens (Human)1.01376Known
O15075Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK19201;Homo sapiens (Human)1.0088448
Q9Y5Y9Sodium channel protein type 10 subunit alpha (Peripheral nerve sodium ...Sodium channel (TC 1.A.1.10) family, Nav1.8/SCN10A subfamilySCN10A6336;Homo sapiens (Human)0.98874649
P42338Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) ...PI3/PI4-kinase familyPIK3CB5291;Homo sapiens (Human)0.978994Known
Q9BVS4Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK255781;Homo sapiens (Human)0.974281Known
Q9Y5S2Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPB9578;Homo sapiens (Human)0.963225Known
Q9Y243RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT310000;Homo sapiens (Human)0.958426Known
Q8IVW4Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine-protein kinase NKIAMRE)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL351265;Homo sapiens (Human)0.955658Known
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)0.95200550
Q6DT37Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPG55561;Homo sapiens (Human)0.948141Known
Q8IY84Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyNIM1K167359;Homo sapiens (Human)0.937756Known
P54756Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA52044;Homo sapiens (Human)0.914521Known
Q8TDX7Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK7140609;Homo sapiens (Human)0.909295Known
Q8TD19Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK991754;Homo sapiens (Human)0.893486Known
P54764Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA42043;Homo sapiens (Human)0.872111Known
Q13705Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2B93;Homo sapiens (Human)0.868313Known
Q6P3R8Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK5341676;Homo sapiens (Human)0.86005Known
Q96PY6Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK14750;Homo sapiens (Human)0.855231Known
Q13873Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR2659;Homo sapiens (Human)0.83322Known
P36894Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1A657;Homo sapiens (Human)0.832557Known
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)0.82388Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)0.798916Known
Q9Y6R4Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K44216;Homo sapiens (Human)0.783115Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)0.782296Known
Q8N752Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A1L122011;Homo sapiens (Human)0.774935Known
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)0.709342Known
P37023Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVRL194;Homo sapiens (Human)0.673683Known
O95747Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyOXSR19943;Homo sapiens (Human)0.657987Known
P27037Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2A92;Homo sapiens (Human)0.581325Known
P0C1S8Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) ...Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE2494551;Homo sapiens (Human)0.540133Known
Q9NRP7Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)Protein kinase superfamily, Ser/Thr protein kinase familySTK3627148;Homo sapiens (Human)0.524354Known
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)0.428219Known
P27361Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK35595;Homo sapiens (Human)0.312107Known
P42858Huntingtin (Huntington disease protein) (HD protein)Huntingtin familyHTT3064;Homo sapiens (Human)0.294048Known

[5] CHEMBL4097778

Original SMILES:
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21

Prepared SMILES:
O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1

O43614Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type ...G-protein coupled receptor 1 familyHCRTR23062;Homo sapiens (Human)2.897821
P32239Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R)G-protein coupled receptor 1 familyCCKBR887;Homo sapiens (Human)2.896572
P49286Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)G-protein coupled receptor 1 familyMTNR1B4544;Homo sapiens (Human)2.790873
P460985-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) ...Ligand-gated ion channel (TC 1.A.9) family, 5-hydroxytryptamine receptor (TC 1.A.9.2) ...HTR3A3359;Homo sapiens (Human)2.784474
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)2.784385
Q13093Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47) (1-alkyl-2-acetylglycerophosphocholine esterase) (2-acetyl-1-alkylglycerophosphocholine ...AB hydrolase superfamily, Lipase familyPLA2G77941;Homo sapiens (Human)2.644066
P089085-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamilyHTR1A3350;Homo sapiens (Human)2.515417
O00763Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC ...ACACB32;Homo sapiens (Human)2.515038
P00918Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA2760;Homo sapiens (Human)2.483619
Q14703Membrane-bound transcription factor site-1 protease (EC 3.4.21.112) (Endopeptidase S1P) (Subtilisin/kexin-isozyme ...Peptidase S8 familyMBTPS18720;Homo sapiens (Human)2.4332310
P30559Oxytocin receptor (OT-R)G-protein coupled receptor 1 family, Vasopressin/oxytocin receptor subfamilyOXTR5021;Homo sapiens (Human)2.431711
P31644Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A) receptor subunit alpha-5)Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC ...GABRA52558;Homo sapiens (Human)2.3650812
P03372Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 ...Nuclear hormone receptor family, NR3 subfamilyESR12099;Homo sapiens (Human)2.1623513
P30536Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR)TspO/BZRP familyTSPO706;Homo sapiens (Human)2.1224414
O43613Orexin receptor type 1 (Ox-1-R) (Ox1-R) (Ox1R) (Hypocretin receptor type ...G-protein coupled receptor 1 familyHCRTR13061;Homo sapiens (Human)2.0952715
P35372Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid ...G-protein coupled receptor 1 familyOPRM14988;Homo sapiens (Human)2.0618916
P48039Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)G-protein coupled receptor 1 familyMTNR1A4543;Homo sapiens (Human)2.0526817
P34972Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)G-protein coupled receptor 1 familyCNR21269;Homo sapiens (Human)1.9924818
P35462D(3) dopamine receptor (Dopamine D3 receptor)G-protein coupled receptor 1 familyDRD31814;Homo sapiens (Human)1.9923219
O00748Cocaine esterase (EC 3.1.1.84) (Carboxylesterase 2) (CE-2) (hCE-2) (EC 3.1.1.1) ...Type-B carboxylesterase/lipase familyCES28824;Homo sapiens (Human)1.9407520
Q99705Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein ...G-protein coupled receptor 1 familyMCHR12847;Homo sapiens (Human)1.9223121
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.8958622
P27487Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein ...Peptidase S9B family, DPPIV subfamilyDPP41803;Homo sapiens (Human)1.8640623
P23141Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) ...Type-B carboxylesterase/lipase familyCES11066;Homo sapiens (Human)1.8564924
Q13085Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (Acetyl-Coenzyme A carboxylase alpha) ...ACACA31;Homo sapiens (Human)1.8488525
P41594Metabotropic glutamate receptor 5 (mGluR5)G-protein coupled receptor 3 familyGRM52915;Homo sapiens (Human)1.7773526
P283355-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) ...G-protein coupled receptor 1 familyHTR2C3358;Homo sapiens (Human)1.7729527
P14324Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate ...FPP/GGPP synthase familyFDPS2224;Homo sapiens (Human)1.751828
P08842Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase)Sulfatase familySTS412;Homo sapiens (Human)1.7463329
P07550Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB2 sub-subfamilyADRB2154;Homo sapiens (Human)1.7183630
Q14416Metabotropic glutamate receptor 2 (mGluR2)G-protein coupled receptor 3 familyGRM22912;Homo sapiens (Human)1.7126331
P27815cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.53) (DPDE2) (PDE46)Cyclic nucleotide phosphodiesterase family, PDE4 subfamilyPDE4A5141;Homo sapiens (Human)1.6711132
P35348Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) ...G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1A sub-subfamilyADRA1A148;Homo sapiens (Human)1.6651633
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)1.6591834
Q15722Leukotriene B4 receptor 1 (LTB4-R 1) (LTB4-R1) (Chemoattractant receptor-like 1) ...G-protein coupled receptor 1 familyLTB4R1241;Homo sapiens (Human)1.6466735
P10275Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C ...Nuclear hormone receptor family, NR3 subfamilyAR367;Homo sapiens (Human)1.6328336
Q16790Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA9768;Homo sapiens (Human)1.6029637
P47211Galanin receptor type 1 (GAL1-R) (GALR-1)G-protein coupled receptor 1 familyGALR12587;Homo sapiens (Human)1.6002938
P21554Cannabinoid receptor 1 (CB-R) (CB1) (CANN6)G-protein coupled receptor 1 familyCNR11268;Homo sapiens (Human)1.5901539
P48067Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier ...Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A9 subfamilySLC6A96536;Homo sapiens (Human)1.5857840
P08246Neutrophil elastase (EC 3.4.21.37) (Bone marrow serine protease) (Elastase-2) (Human ...Peptidase S1 family, Elastase subfamilyELANE1991;Homo sapiens (Human)1.5830141
P49810Presenilin-2 (PS-2) (EC 3.4.23.-) (AD3LP) (AD5) (E5-1) (STM-2) [Cleaved into: ...Peptidase A22A familyPSEN25664;Homo sapiens (Human)1.5710942
Q9Y5Y4Prostaglandin D2 receptor 2 (Chemoattractant receptor-homologous molecule expressed on Th2 ...G-protein coupled receptor 1 familyPTGDR211251;Homo sapiens (Human)1.5624943
P04150Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member ...Nuclear hormone receptor family, NR3 subfamilyNR3C12908;Homo sapiens (Human)1.5490644
P51681C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5) ...G-protein coupled receptor 1 familyCCR51234;Homo sapiens (Human)1.547545
Q92731Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A ...Nuclear hormone receptor family, NR3 subfamilyESR22100;Homo sapiens (Human)1.538446
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)1.5297547
P00748Coagulation factor XII (EC 3.4.21.38) (Hageman factor) (HAF) [Cleaved into: ...Peptidase S1 familyF122161;Homo sapiens (Human)1.4797348
P08588Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor)G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB1 sub-subfamilyADRB1153;Homo sapiens (Human)1.4693849
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)1.4633150

[6] CHEMBL4088216

Original SMILES:
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21

Prepared SMILES:
O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1

O43614Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type ...G-protein coupled receptor 1 familyHCRTR23062;Homo sapiens (Human)2.791221
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)2.784382
O00763Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC ...ACACB32;Homo sapiens (Human)2.515033
P08842Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase)Sulfatase familySTS412;Homo sapiens (Human)2.446074
Q14703Membrane-bound transcription factor site-1 protease (EC 3.4.21.112) (Endopeptidase S1P) (Subtilisin/kexin-isozyme ...Peptidase S8 familyMBTPS18720;Homo sapiens (Human)2.433235
P49286Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)G-protein coupled receptor 1 familyMTNR1B4544;Homo sapiens (Human)2.361056
P460985-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) ...Ligand-gated ion channel (TC 1.A.9) family, 5-hydroxytryptamine receptor (TC 1.A.9.2) ...HTR3A3359;Homo sapiens (Human)2.349827
P089085-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamilyHTR1A3350;Homo sapiens (Human)2.315578
P48039Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)G-protein coupled receptor 1 familyMTNR1A4543;Homo sapiens (Human)2.275079
P32239Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R)G-protein coupled receptor 1 familyCCKBR887;Homo sapiens (Human)2.2695210
P29275Adenosine receptor A2bG-protein coupled receptor 1 familyADORA2B136;Homo sapiens (Human)2.2425811
P00918Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA2760;Homo sapiens (Human)2.1540612
P30536Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR)TspO/BZRP familyTSPO706;Homo sapiens (Human)2.1468513
O43613Orexin receptor type 1 (Ox-1-R) (Ox1-R) (Ox1R) (Hypocretin receptor type ...G-protein coupled receptor 1 familyHCRTR13061;Homo sapiens (Human)2.1069414
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)1.997215
P34972Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)G-protein coupled receptor 1 familyCNR21269;Homo sapiens (Human)1.9924816
P21554Cannabinoid receptor 1 (CB-R) (CB1) (CANN6)G-protein coupled receptor 1 familyCNR11268;Homo sapiens (Human)1.9563817
P41594Metabotropic glutamate receptor 5 (mGluR5)G-protein coupled receptor 3 familyGRM52915;Homo sapiens (Human)1.9520818
P30559Oxytocin receptor (OT-R)G-protein coupled receptor 1 family, Vasopressin/oxytocin receptor subfamilyOXTR5021;Homo sapiens (Human)1.9461619
P04150Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member ...Nuclear hormone receptor family, NR3 subfamilyNR3C12908;Homo sapiens (Human)1.9381720
Q99705Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein ...G-protein coupled receptor 1 familyMCHR12847;Homo sapiens (Human)1.9223121
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.8958622
P23141Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) ...Type-B carboxylesterase/lipase familyCES11066;Homo sapiens (Human)1.8564923
Q13085Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (Acetyl-Coenzyme A carboxylase alpha) ...ACACA31;Homo sapiens (Human)1.8488524
P03372Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 ...Nuclear hormone receptor family, NR3 subfamilyESR12099;Homo sapiens (Human)1.8018725
Q15722Leukotriene B4 receptor 1 (LTB4-R 1) (LTB4-R1) (Chemoattractant receptor-like 1) ...G-protein coupled receptor 1 familyLTB4R1241;Homo sapiens (Human)1.7828726
P35372Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid ...G-protein coupled receptor 1 familyOPRM14988;Homo sapiens (Human)1.7798827
P283355-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) ...G-protein coupled receptor 1 familyHTR2C3358;Homo sapiens (Human)1.7306528
O43683Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)Protein kinase superfamily, Ser/Thr protein kinase family, BUB1 subfamilyBUB1699;Homo sapiens (Human)1.6725829
P10275Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C ...Nuclear hormone receptor family, NR3 subfamilyAR367;Homo sapiens (Human)1.6328330
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)1.6172131
Q16790Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA9768;Homo sapiens (Human)1.564532
Q9Y5Y4Prostaglandin D2 receptor 2 (Chemoattractant receptor-homologous molecule expressed on Th2 ...G-protein coupled receptor 1 familyPTGDR211251;Homo sapiens (Human)1.5624933
P27487Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein ...Peptidase S9B family, DPPIV subfamilyDPP41803;Homo sapiens (Human)1.5603434
P08246Neutrophil elastase (EC 3.4.21.37) (Bone marrow serine protease) (Elastase-2) (Human ...Peptidase S1 family, Elastase subfamilyELANE1991;Homo sapiens (Human)1.5553135
P35462D(3) dopamine receptor (Dopamine D3 receptor)G-protein coupled receptor 1 familyDRD31814;Homo sapiens (Human)1.5269536
Q13507Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein ...Transient receptor (TC 1.A.4) family, STrpC subfamily, TRPC3 sub-subfamilyTRPC37222;Homo sapiens (Human)1.5036337
P00748Coagulation factor XII (EC 3.4.21.38) (Hageman factor) (HAF) [Cleaved into: ...Peptidase S1 familyF122161;Homo sapiens (Human)1.4963738
P21917D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)G-protein coupled receptor 1 familyDRD41815;Homo sapiens (Human)1.448239
Q9GZN0Probable G-protein coupled receptor 88 (Striatum-specific G-protein coupled receptor)G-protein coupled receptor 1 familyGPR8854112;Homo sapiens (Human)1.4208640
P07550Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB2 sub-subfamilyADRB2154;Homo sapiens (Human)1.4105241
P07339Cathepsin D (EC 3.4.23.5) [Cleaved into: Cathepsin D light chain; ...Peptidase A1 familyCTSD1509;Homo sapiens (Human)1.3893342
P35348Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) ...G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1A sub-subfamilyADRA1A148;Homo sapiens (Human)1.3801443
Q96C86m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed ...HIT familyDCPS28960;Homo sapiens (Human)1.3797144
P35368Alpha-1B adrenergic receptor (Alpha-1B adrenoreceptor) (Alpha-1B adrenoceptor)G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1B sub-subfamilyADRA1B147;Homo sapiens (Human)1.3602445
Q99720Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding ...ERG2 familySIGMAR110280;Homo sapiens (Human)1.3163946
P30556Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) ...G-protein coupled receptor 1 familyAGTR1185;Homo sapiens (Human)1.3141147
P42574Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein ...Peptidase C14A familyCASP3836;Homo sapiens (Human)1.3083348
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)1.3003249
P14867Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) receptor subunit alpha-1)Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC ...GABRA12554;Homo sapiens (Human)1.2905150

[7] CHEMBL4549667

Original SMILES:
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21

Prepared SMILES:
O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1

P34972Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)G-protein coupled receptor 1 familyCNR21269;Homo sapiens (Human)3.271391
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)3.116412
O43614Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type ...G-protein coupled receptor 1 familyHCRTR23062;Homo sapiens (Human)3.065083
O43613Orexin receptor type 1 (Ox-1-R) (Ox1-R) (Ox1R) (Hypocretin receptor type ...G-protein coupled receptor 1 familyHCRTR13061;Homo sapiens (Human)2.989464
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)2.898365
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)2.837796
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)2.797747
P49286Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)G-protein coupled receptor 1 familyMTNR1B4544;Homo sapiens (Human)2.73188
P32239Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R)G-protein coupled receptor 1 familyCCKBR887;Homo sapiens (Human)2.662959
P00918Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA2760;Homo sapiens (Human)2.6614910
P08842Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase)Sulfatase familySTS412;Homo sapiens (Human)2.6403611
P35462D(3) dopamine receptor (Dopamine D3 receptor)G-protein coupled receptor 1 familyDRD31814;Homo sapiens (Human)2.5803412
Q14703Membrane-bound transcription factor site-1 protease (EC 3.4.21.112) (Endopeptidase S1P) (Subtilisin/kexin-isozyme ...Peptidase S8 familyMBTPS18720;Homo sapiens (Human)2.4332313
P30536Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR)TspO/BZRP familyTSPO706;Homo sapiens (Human)2.392714
P21554Cannabinoid receptor 1 (CB-R) (CB1) (CANN6)G-protein coupled receptor 1 familyCNR11268;Homo sapiens (Human)2.261515
P460985-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) ...Ligand-gated ion channel (TC 1.A.9) family, 5-hydroxytryptamine receptor (TC 1.A.9.2) ...HTR3A3359;Homo sapiens (Human)2.1968316
P30559Oxytocin receptor (OT-R)G-protein coupled receptor 1 family, Vasopressin/oxytocin receptor subfamilyOXTR5021;Homo sapiens (Human)2.1229917
P283355-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) ...G-protein coupled receptor 1 familyHTR2C3358;Homo sapiens (Human)2.0497718
Q92731Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A ...Nuclear hormone receptor family, NR3 subfamilyESR22100;Homo sapiens (Human)2.035519
P48039Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)G-protein coupled receptor 1 familyMTNR1A4543;Homo sapiens (Human)2.0036520
P03372Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 ...Nuclear hormone receptor family, NR3 subfamilyESR12099;Homo sapiens (Human)1.9839321
O00748Cocaine esterase (EC 3.1.1.84) (Carboxylesterase 2) (CE-2) (hCE-2) (EC 3.1.1.1) ...Type-B carboxylesterase/lipase familyCES28824;Homo sapiens (Human)1.9836922
P41594Metabotropic glutamate receptor 5 (mGluR5)G-protein coupled receptor 3 familyGRM52915;Homo sapiens (Human)1.9747323
P089085-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamilyHTR1A3350;Homo sapiens (Human)1.9679524
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)1.9384225
Q15722Leukotriene B4 receptor 1 (LTB4-R 1) (LTB4-R1) (Chemoattractant receptor-like 1) ...G-protein coupled receptor 1 familyLTB4R1241;Homo sapiens (Human)1.9316126
P41145Kappa-type opioid receptor (K-OR-1) (KOR-1)G-protein coupled receptor 1 familyOPRK14986;Homo sapiens (Human)1.8811127
P30556Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) ...G-protein coupled receptor 1 familyAGTR1185;Homo sapiens (Human)1.8565728
P23141Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) ...Type-B carboxylesterase/lipase familyCES11066;Homo sapiens (Human)1.8485429
O43683Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)Protein kinase superfamily, Ser/Thr protein kinase family, BUB1 subfamilyBUB1699;Homo sapiens (Human)1.8191430
P00748Coagulation factor XII (EC 3.4.21.38) (Hageman factor) (HAF) [Cleaved into: ...Peptidase S1 familyF122161;Homo sapiens (Human)1.7806431
P27487Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein ...Peptidase S9B family, DPPIV subfamilyDPP41803;Homo sapiens (Human)1.7560232
Q16790Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA9768;Homo sapiens (Human)1.7359833
P35368Alpha-1B adrenergic receptor (Alpha-1B adrenoreceptor) (Alpha-1B adrenoceptor)G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1B sub-subfamilyADRA1B147;Homo sapiens (Human)1.7294434
P08246Neutrophil elastase (EC 3.4.21.37) (Bone marrow serine protease) (Elastase-2) (Human ...Peptidase S1 family, Elastase subfamilyELANE1991;Homo sapiens (Human)1.7122135
P35348Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) ...G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1A sub-subfamilyADRA1A148;Homo sapiens (Human)1.7110636
P00742Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved ...Peptidase S1 familyF102159;Homo sapiens (Human)1.6905237
P07550Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB2 sub-subfamilyADRB2154;Homo sapiens (Human)1.6404238
Q13507Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein ...Transient receptor (TC 1.A.4) family, STrpC subfamily, TRPC3 sub-subfamilyTRPC37222;Homo sapiens (Human)1.6385139
Q12809Potassium voltage-gated channel subfamily H member 2 (Eag homolog) (Ether-a-go-go-related ...Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.1/KCNH2 sub-subfamilyKCNH23757;Homo sapiens (Human)1.6350440
P31645Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family ...Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamilySLC6A46532;Homo sapiens (Human)1.6262141
P43681Neuronal acetylcholine receptor subunit alpha-4Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) ...CHRNA41137;Homo sapiens (Human)1.5834642
P52732Kinesin-like protein KIF11 (Kinesin-like protein 1) (Kinesin-like spindle protein HKSP) ...TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, BimC subfamilyKIF113832;Homo sapiens (Human)1.5757843
P32238Cholecystokinin receptor type A (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R)G-protein coupled receptor 1 familyCCKAR886;Homo sapiens (Human)1.5575744
Q96C86m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed ...HIT familyDCPS28960;Homo sapiens (Human)1.5387645
P34913Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) ...AB hydrolase superfamily, Epoxide hydrolase familyEPHX22053;Homo sapiens (Human)1.5309546
P07339Cathepsin D (EC 3.4.23.5) [Cleaved into: Cathepsin D light chain; ...Peptidase A1 familyCTSD1509;Homo sapiens (Human)1.5295347
Q9GZN0Probable G-protein coupled receptor 88 (Striatum-specific G-protein coupled receptor)G-protein coupled receptor 1 familyGPR8854112;Homo sapiens (Human)1.5194848
Q99720Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding ...ERG2 familySIGMAR110280;Homo sapiens (Human)1.4883449
Q13258Prostaglandin D2 receptor (PGD receptor) (PGD2 receptor) (Prostanoid DP receptor)G-protein coupled receptor 1 familyPTGDR5729;Homo sapiens (Human)1.4863550

[8] CHEMBL509032

Original SMILES:
COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1

Prepared SMILES:
COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C

Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)4.00904Known
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)3.76307Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)3.5761Known
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)3.15588Known
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)3.12273Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)3.00548Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)2.88619Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)2.86536Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)2.77027Known
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)2.740771
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)2.72475Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)2.70332Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)2.65621Known
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)2.64528Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)2.60443Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)2.57474Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)2.55623Known
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)2.55275Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)2.53491Known
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)2.530772
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)2.47879Known
P35462D(3) dopamine receptor (Dopamine D3 receptor)G-protein coupled receptor 1 familyDRD31814;Homo sapiens (Human)2.475163
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)2.47398Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)2.4737Known
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)2.47076Known
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)2.35606Known
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)2.30172Known
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)2.29221Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)2.28968Known
P53350Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK15347;Homo sapiens (Human)2.25333Known
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)2.25138Known
P504065-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)G-protein coupled receptor 1 familyHTR63362;Homo sapiens (Human)2.225224
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)2.216415
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)2.21028Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)2.17946Known
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)2.155476
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)2.14458Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)2.14408Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)2.13501Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)2.12481Known
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)2.12471Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.1092Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)2.1088Known
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)2.09742Known
Q13164Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK75598;Homo sapiens (Human)2.09665Known
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)2.08396Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)2.0715Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)2.06436Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)2.05507Known
Q9C098Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK385443;Homo sapiens (Human)2.04235Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)2.0404Known
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)2.03824Known
Q96D53Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase ...Protein kinase superfamily, ADCK protein kinase familyCOQ8B79934;Homo sapiens (Human)2.03294Known
Q9NYY3Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK210769;Homo sapiens (Human)2.02516Known
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)2.02475Known
Q00537Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK175128;Homo sapiens (Human)2.02361Known
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)2.01297Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)2.01277Known
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)2.00218Known
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)1.99752Known
Q9BWU1Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1923097;Homo sapiens (Human)1.978027
Q00526Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK31018;Homo sapiens (Human)1.961318
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)1.95992Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)1.95974Known
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)1.95969Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)1.94968Known
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.93623Known
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.93332Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)1.9278Known
P17252Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCA5578;Homo sapiens (Human)1.923069
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)1.92229Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)1.86016Known
P14616Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSRR3645;Homo sapiens (Human)1.85156Known
Q96L34MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK457787;Homo sapiens (Human)1.83351Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)1.82373Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)1.81939Known
Q13705Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2B93;Homo sapiens (Human)1.81534Known
Q15759Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK115600;Homo sapiens (Human)1.8146110
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)1.80832Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)1.79978Known
Q15046Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)Class-II aminoacyl-tRNA synthetase familyKARS3735;Homo sapiens (Human)1.79622Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)1.78936Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)1.78821Known
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)1.7867Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)1.78107Known
P53355Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK11612;Homo sapiens (Human)1.76696Known
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)1.76631Known
Q52WX2Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySBK1388228;Homo sapiens (Human)1.76587Known
O14920Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKB3551;Homo sapiens (Human)1.7622211
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)1.75504Known
Q8N568Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK2166614;Homo sapiens (Human)1.75235Known
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)1.73965Known
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)1.73931Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)1.73397Known
O94921Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK145218;Homo sapiens (Human)1.7265412
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.72406Known
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)1.7224913
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)1.71101Known
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.71066Known
Q9UIK4Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK223604;Homo sapiens (Human)1.7093Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)1.70609Known
Q9BXA7Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK1B83942;Homo sapiens (Human)1.70609Known
Q9NWT8Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, ...Mitochondrion-specific ribosomal protein mS38 familyAURKAIP154998;Homo sapiens (Human)1.7007314
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)1.6917Known
Q13557Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2D817;Homo sapiens (Human)1.68724Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)1.67716Known
P20794Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyMAK4117;Homo sapiens (Human)1.6728915
O75914Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK35063;Homo sapiens (Human)1.66518Known
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)1.66292Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)1.66196Known
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.6589Known
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)1.65166Known
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.6404Known
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)1.6289516
O94768Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17B9262;Homo sapiens (Human)1.62259Known
P49761Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK31198;Homo sapiens (Human)1.62144Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)1.61811Known
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)1.61597Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)1.61497Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)1.61005Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)1.60255Known
P37023Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVRL194;Homo sapiens (Human)1.58824Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.587Known
Q8TD08Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15225689;Homo sapiens (Human)1.5813Known
Q8TD19Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK991754;Homo sapiens (Human)1.56959Known
Q9P286Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK557144;Homo sapiens (Human)1.5677Known
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)1.56067Known
P04049RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyRAF15894;Homo sapiens (Human)1.559717
O15146Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase familyMUSK4593;Homo sapiens (Human)1.55121Known
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.55001Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)1.54795Known
Q13555Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2G818;Homo sapiens (Human)1.5471Known
Q00534Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK61021;Homo sapiens (Human)1.5440918
P05771Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCB5579;Homo sapiens (Human)1.5370119
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.5348Known
P0C1S8Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) ...Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE2494551;Homo sapiens (Human)1.5312220
P27448MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK34140;Homo sapiens (Human)1.53071Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)1.51014Known
P24723Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCH5583;Homo sapiens (Human)1.5094321
Q02779Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K104294;Homo sapiens (Human)1.50494Known
P21917D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)G-protein coupled receptor 1 familyDRD41815;Homo sapiens (Human)1.5034622
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.50303Known
O15111Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyCHUK1147;Homo sapiens (Human)1.5028723
Q9P0L2Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK14139;Homo sapiens (Human)1.50212Known
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)1.4972724
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.48687Known
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.4715225
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)1.46919Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)1.46887Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)1.46663Known
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)1.46522Known
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)1.46446Known
P30291Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE17465;Homo sapiens (Human)1.46222Known
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)1.460326
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.45312Known
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)1.44811Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)1.44471Known
P28482Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15594;Homo sapiens (Human)1.44064Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)1.43467Known
Q9Y6E0Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK248428;Homo sapiens (Human)1.43248Known
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)1.43097Known
Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)1.4291827
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)1.42465Known
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.42418Known
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)1.42327Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)1.41367Known
P78362SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK26733;Homo sapiens (Human)1.412228
P37173TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR27048;Homo sapiens (Human)1.4027Known
Q8TDX7Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK7140609;Homo sapiens (Human)1.40186Known
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)1.396329
P54756Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA52044;Homo sapiens (Human)1.39364Known
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)1.3878630
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)1.38658Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)1.38537Known
P54753Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB32049;Homo sapiens (Human)1.38217Known
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)1.3767231
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)1.3730732
P0C264Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family ...Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamilySBK3100130827;Homo sapiens (Human)1.37127Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)1.36842Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.36839Known
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)1.36764Known
Q8IVW4Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine-protein kinase NKIAMRE)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL351265;Homo sapiens (Human)1.35433
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)1.35316Known
Q9H4B4Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK31263;Homo sapiens (Human)1.34846Known
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)1.34832Known
Q05513Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCZ5590;Homo sapiens (Human)1.3421934
Q16816Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG15260;Homo sapiens (Human)1.3396Known
P49674Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1E102800317;1454;Homo sapiens (Human)1.3276635
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)1.31772Known
Q13237cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG25593;Homo sapiens (Human)1.31484Known
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)1.31379Known
Q15139Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD15587;Homo sapiens (Human)1.3087Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)1.30637Known
P546465'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA25563;Homo sapiens (Human)1.30464Known
P51957Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK46787;Homo sapiens (Human)1.29897Known
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)1.29578Known
Q92772Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL28999;Homo sapiens (Human)1.2924336
P36896Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR1B91;Homo sapiens (Human)1.29087Known
Q8IW41MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMAPKAPK58550;Homo sapiens (Human)1.2900137
P48736Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) ...PI3/PI4-kinase familyPIK3CG5294;Homo sapiens (Human)1.2885238
Q9HC98Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK610783;Homo sapiens (Human)1.28548Known
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)1.28547Known
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.28395Known
Q15831Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamilySTK116794;Homo sapiens (Human)1.2829139
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.28063Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.27212Known
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)1.2659Known
Q13153Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK15058;Homo sapiens (Human)1.26583Known
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)1.26092Known
Q9Y2K2Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK323387;Homo sapiens (Human)1.25849Known
Q96SB4SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK16732;Homo sapiens (Human)1.25626Known
Q15569Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyTESK17016;Homo sapiens (Human)1.255640
O00311Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamilyCDC78317;Homo sapiens (Human)1.2538241
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.25336Known
P089085-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamilyHTR1A3350;Homo sapiens (Human)1.2529742
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)1.25Known
Q13976cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG15592;Homo sapiens (Human)1.24352Known
Q96PF2Testis-specific serine/threonine-protein kinase 2 (TSK-2) (TSK2) (TSSK-2) (Testis-specific kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK223617;Homo sapiens (Human)1.24035Known
P00374Dihydrofolate reductase (EC 1.5.1.3)Dihydrofolate reductase familyDHFR1719;Homo sapiens (Human)1.2361643
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.23598Known
Q8TBX8Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2C79837;Homo sapiens (Human)1.22623Known
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)1.224944
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)1.22233Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)1.21672Known
O14936Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; ...CASK8573;Homo sapiens (Human)1.21261Known
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)1.2094745
Q00535Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK51020;Homo sapiens (Human)1.20421Known
Q13177Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK25062;Homo sapiens (Human)1.20409Known
Q9Y463Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1B9149;Homo sapiens (Human)1.203Known
Q9BX84Transient receptor potential cation channel subfamily M member 6 (EC ...Protein kinase superfamily, Alpha-type protein kinase family, ALPK subfamily; Transient ...TRPM6140803;Homo sapiens (Human)1.2026846
Q9NRP7Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)Protein kinase superfamily, Ser/Thr protein kinase familySTK3627148;Homo sapiens (Human)1.19919Known
O15264Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK135603;Homo sapiens (Human)1.197247
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.19617Known
Q9BRS2Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK183732;Homo sapiens (Human)1.1959248
P42336Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) ...PI3/PI4-kinase familyPIK3CA5290;Homo sapiens (Human)1.1922849
Q15375Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA72045;Homo sapiens (Human)1.19088Known
P19525Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK25610;Homo sapiens (Human)1.1848950
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)1.18375Known
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)1.18362Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)1.17793Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)1.17595Known
P36894Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1A657;Homo sapiens (Human)1.1735Known
Q96Q40Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1565061;Homo sapiens (Human)1.17046Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.1514Known
Q9Y2H9Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)Protein kinase superfamily, AGC Ser/Thr protein kinase familyMAST122983;Homo sapiens (Human)1.14875Known
P29323Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB22048;Homo sapiens (Human)1.14735Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.1471Known
Q8WU08Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySTK32A202374;Homo sapiens (Human)1.14252Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)1.14218Known
P45985Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K46416;Homo sapiens (Human)1.14205Known
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2A815;Homo sapiens (Human)1.14189Known
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)1.14125Known
O15075Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK19201;Homo sapiens (Human)1.1376Known
O14730Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK38780;Homo sapiens (Human)1.1328Known
Q9UEE5Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17A9263;Homo sapiens (Human)1.12867Known
Q6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein ...Protein kinase superfamily, Ser/Thr protein kinase familyDSTYK25778;Homo sapiens (Human)1.12203Known
Q13627Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1A1859;Homo sapiens (Human)1.11086Known
Q7KZI7Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK22011;Homo sapiens (Human)1.1056Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.09651Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.09535Known
Q8TDC3Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK184446;Homo sapiens (Human)1.09213Known
Q8WXR4Myosin-IIIb (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3B140469;Homo sapiens (Human)1.08672Known
Q9UEW8STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK3927347;Homo sapiens (Human)1.08117Known
P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR17046;Homo sapiens (Human)1.07603Known
Q9P289Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2651765;Homo sapiens (Human)1.06621Known
P42680Tyrosine-protein kinase Tec (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTEC7006;Homo sapiens (Human)1.06433Known
Q6DT37Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPG55561;Homo sapiens (Human)1.06268Known
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)1.05506Known
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.04991Known
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)1.04961Known
Q16566Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK4814;Homo sapiens (Human)1.0492Known
Q15835Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK16011;Homo sapiens (Human)1.04655Known
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.04615Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)1.04107Known
Q16512Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN15585;Homo sapiens (Human)1.0363Known
Q04759Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCQ5588;Homo sapiens (Human)1.03524Known
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)1.03312Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)1.0321Known
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)1.03005Known
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)1.02892Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)1.02851Known
O95747Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyOXSR19943;Homo sapiens (Human)1.02255Known
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)1.02109Known
Q9NY57Serine/threonine-protein kinase 32B (EC 2.7.11.1) (Yet another novel kinase 2)Protein kinase superfamily, Ser/Thr protein kinase familySTK32B55351;Homo sapiens (Human)1.02039Known
P43403Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) ...Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilyZAP707535;Homo sapiens (Human)0.976776Known
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)0.970519Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)0.963359Known
Q14012Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK18536;Homo sapiens (Human)0.950981Known
Q9Y5S2Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPB9578;Homo sapiens (Human)0.949954Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)0.94974Known
Q8WTQ7Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK7131890;Homo sapiens (Human)0.949569Known
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)0.9429Known
Q9NRH2SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familySNRK54861;Homo sapiens (Human)0.942687Known
P51956Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (HSPK 36) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK34752;Homo sapiens (Human)0.939727Known
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)0.938567Known
O75460Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyERN12081;Homo sapiens (Human)0.92831Known
Q9UBF8Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) ...PI3/PI4-kinase family, Type III PI4K subfamilyPI4KB5298;Homo sapiens (Human)0.926215Known
P54764Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA42043;Homo sapiens (Human)0.907336Known
P27037Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2A92;Homo sapiens (Human)0.886185Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)0.861329Known
Q09013Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyDMPK1760;Homo sapiens (Human)0.857513Known
P53671LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK23985;Homo sapiens (Human)0.855873Known
P34947G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK52869;Homo sapiens (Human)0.852924Known
Q99755Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC ...PIP5K1A8394;Homo sapiens (Human)0.849105Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)0.848537Known
Q13523Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familyPRPF4B8899;Homo sapiens (Human)0.845499Known
Q59H18Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase ...TNNI3K100526835;51086;Homo sapiens (Human)0.843138Known
P57078Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK4Homo sapiens (Human)0.842203Known
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)0.837655Known
P22694cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACB5567;Homo sapiens (Human)0.831752Known
P52564Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K65608;Homo sapiens (Human)0.822751Known
P27361Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK35595;Homo sapiens (Human)0.821099Known
Q8IY84Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyNIM1K167359;Homo sapiens (Human)0.808886Known
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)0.804138Known
P41240Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyCSK1445;Homo sapiens (Human)0.800388Known
Q05655Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCD5580;Homo sapiens (Human)0.795774Known
P51955Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK24751;Homo sapiens (Human)0.79213Known
Q8NEV4Myosin-IIIa (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3A53904;Homo sapiens (Human)0.78376Known
P53778Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK126300;Homo sapiens (Human)0.756721Known
Q6ZN16Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K15389840;Homo sapiens (Human)0.731557Known
O95835Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS19113;Homo sapiens (Human)0.728438Known
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)0.723863Known
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)0.713492Known
Q86UX6Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (Yet another novel kinase ...Protein kinase superfamily, Ser/Thr protein kinase familySTK32C282974;Homo sapiens (Human)0.711188Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)0.683777Known
Q8NI60Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 ...Protein kinase superfamily, ADCK protein kinase familyCOQ8A56997;Homo sapiens (Human)0.665257Known
P51817cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKX5613;Homo sapiens (Human)0.659143Known
Q8IWQ3Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK29024;Homo sapiens (Human)0.643507Known
Q8NFD2Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyANKK1255239;Homo sapiens (Human)0.638169Known
P42679Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic ...Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyMATK4145;Homo sapiens (Human)0.636976Known
Q96NX5Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1G57172;Homo sapiens (Human)0.635514Known
Q9Y6R4Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K44216;Homo sapiens (Human)0.620166Known
Q9NRM7Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS226524;Homo sapiens (Human)0.617385Known
Q13873Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR2659;Homo sapiens (Human)0.582962Known
Q8N752Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A1L122011;Homo sapiens (Human)0.564591Known
Q9NQU5Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK6106821730;56924;Homo sapiens (Human)0.562666Known
Q15208Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySTK3811329;Homo sapiens (Human)0.559751Known
Q5VT25Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPA8476;Homo sapiens (Human)0.546515Known
P57058Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyHUNK30811;Homo sapiens (Human)0.539351Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)0.536623Known
Q9Y2H1Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySTK38L23012;Homo sapiens (Human)0.496741Known
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)0.496439Known
Q13554Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2B816;Homo sapiens (Human)0.461061Known
Q13233Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K14214;Homo sapiens (Human)0.429153Known
Q02156Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCE5581;Homo sapiens (Human)0.425676Known
O00506Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2510494;Homo sapiens (Human)0.334537Known
O95382Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K69064;Homo sapiens (Human)0.204656Known

[9] CHEMBL1232461

Original SMILES:
CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21

Prepared SMILES:
CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC

P27986Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K ...PI3K p85 subunit familyPIK3R15295;Homo sapiens (Human)4.148691
P47869Gamma-aminobutyric acid receptor subunit alpha-2 (GABA(A) receptor subunit alpha-2)Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC ...GABRA22555;Homo sapiens (Human)3.57272
P31644Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A) receptor subunit alpha-5)Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC ...GABRA52558;Homo sapiens (Human)3.220583
P34903Gamma-aminobutyric acid receptor subunit alpha-3 (GABA(A) receptor subunit alpha-3)Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC ...GABRA32556;Homo sapiens (Human)3.125134
P30536Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR)TspO/BZRP familyTSPO706;Homo sapiens (Human)2.952725
Q15059Bromodomain-containing protein 3 (RING3-like protein)BRD38019;Homo sapiens (Human)2.83505Known
P14867Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) receptor subunit alpha-1)Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC ...GABRA12554;Homo sapiens (Human)2.383226
P25440Bromodomain-containing protein 2 (O27.1.1) (Really interesting new gene 3 protein)BRD26046;Homo sapiens (Human)2.29132Known
P53350Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK15347;Homo sapiens (Human)2.217437
Q07343cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.53) (DPDE4) (PDE32)Cyclic nucleotide phosphodiesterase family, PDE4 subfamilyPDE4B5142;Homo sapiens (Human)2.216628
O75376Nuclear receptor corepressor 1 (N-CoR) (N-CoR1)N-CoR nuclear receptor corepressors familyNCOR19611;Homo sapiens (Human)2.139829
P42338Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) ...PI3/PI4-kinase familyPIK3CB5291;Homo sapiens (Human)2.0779210
P55201Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140)BRPF17862;Homo sapiens (Human)2.0755311
O60885Bromodomain-containing protein 4 (Protein HUNK1)BRD423476;Homo sapiens (Human)2.06643Known
Q58F21Bromodomain testis-specific protein (Cancer/testis antigen 9) (CT9) (RING3-like protein)BRDT676;Homo sapiens (Human)2.0166412
Q09472Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) ...EP3002033;Homo sapiens (Human)1.8818813
P29275Adenosine receptor A2bG-protein coupled receptor 1 familyADORA2B136;Homo sapiens (Human)1.8668714
O00329Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) ...PI3/PI4-kinase familyPIK3CD5293;Homo sapiens (Human)1.8425515
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)1.7521716
P25105Platelet-activating factor receptor (PAF-R) (PAFr)G-protein coupled receptor 1 familyPTAFR5724;Homo sapiens (Human)1.6909217
Q92793CREB-binding protein (EC 2.3.1.48)CREBBP1387;Homo sapiens (Human)1.6818918
Q969S8Polyamine deacetylase HDAC10 (EC 3.5.1.48) (EC 3.5.1.62) (Histone deacetylase 10) ...Histone deacetylase family, HD type 2 subfamilyHDAC1083933;Homo sapiens (Human)1.6091619
Q6PL18ATPase family AAA domain-containing protein 2 (EC 3.6.1.3) (AAA nuclear ...AAA ATPase familyATAD229028;Homo sapiens (Human)1.5336120
P49286Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)G-protein coupled receptor 1 familyMTNR1B4544;Homo sapiens (Human)1.504721
P48736Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) ...PI3/PI4-kinase familyPIK3CG5294;Homo sapiens (Human)1.4425322
Q9UKV0Histone deacetylase 9 (HD9) (EC 3.5.1.98) (Histone deacetylase 7B) (HD7) ...Histone deacetylase family, HD type 2 subfamilyHDAC99734;Homo sapiens (Human)1.4070923
P42336Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) ...PI3/PI4-kinase familyPIK3CA5290;Homo sapiens (Human)1.3631424
Q9H4B4Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK31263;Homo sapiens (Human)1.3306325
O00750Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 ...PI3/PI4-kinase familyPIK3C2B5287;Homo sapiens (Human)1.246826
Q9NPI1Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1)BRD729117;Homo sapiens (Human)1.2271427
Q9H8M2Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS-40.8)BRD965980;Homo sapiens (Human)1.1887328
Q9BXF3Cat eye syndrome critical region protein 2CECR227443;Homo sapiens (Human)1.1885929
Q92769Histone deacetylase 2 (HD2) (EC 3.5.1.98)Histone deacetylase family, HD type 1 subfamilyHDAC23066;Homo sapiens (Human)1.1419830
Q96DB2Histone deacetylase 11 (HD11) (EC 3.5.1.98)Histone deacetylase familyHDAC1179885;Homo sapiens (Human)1.1326731
P283355-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) ...G-protein coupled receptor 1 familyHTR2C3358;Homo sapiens (Human)1.126532
P78527DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC ...PI3/PI4-kinase familyPRKDC5591;Homo sapiens (Human)1.117133
P51532Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor ...SNF2/RAD54 helicase familySMARCA46597;Homo sapiens (Human)1.0745834
Q13547Histone deacetylase 1 (HD1) (EC 3.5.1.98)Histone deacetylase family, HD type 1 subfamilyHDAC13065;Homo sapiens (Human)1.0704635
P34913Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) ...AB hydrolase superfamily, Epoxide hydrolase familyEPHX22053;Homo sapiens (Human)1.0389836
P41594Metabotropic glutamate receptor 5 (mGluR5)G-protein coupled receptor 3 familyGRM52915;Homo sapiens (Human)1.0093937
Q8WUI4Histone deacetylase 7 (HD7) (EC 3.5.1.98) (Histone deacetylase 7A) (HD7a)Histone deacetylase family, HD type 2 subfamilyHDAC751564;Homo sapiens (Human)0.952538
O15379Histone deacetylase 3 (HD3) (EC 3.5.1.98) (RPD3-2) (SMAP45)Histone deacetylase family, HD type 1 subfamilyHDAC38841;Homo sapiens (Human)0.93906839
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)0.91470540
P48039Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)G-protein coupled receptor 1 familyMTNR1A4543;Homo sapiens (Human)0.88304241
O76074cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)Cyclic nucleotide phosphodiesterase familyPDE5A8654;Homo sapiens (Human)0.87157842
O15164Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 2.3.2.27) (E3 ubiquitin-protein ligase ...TRIM248805;Homo sapiens (Human)0.86297443
Q9UQL6Histone deacetylase 5 (HD5) (EC 3.5.1.98) (Antigen NY-CO-9)Histone deacetylase family, HD type 2 subfamilyHDAC510014;Homo sapiens (Human)0.84593844
P00918Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA2760;Homo sapiens (Human)0.84030945
P312133-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.1.22) (5 alpha-SR2) (SR type 2) ...Steroid 5-alpha reductase familySRD5A26716;Homo sapiens (Human)0.83127246
Q9BY41Histone deacetylase 8 (HD8) (EC 3.5.1.98)Histone deacetylase family, HD type 1 subfamilyHDAC855869;Homo sapiens (Human)0.79596347
P42345Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein ...PI3/PI4-kinase familyMTOR2475;Homo sapiens (Human)0.78922348
P56524Histone deacetylase 4 (HD4) (EC 3.5.1.98)Histone deacetylase family, HD type 2 subfamilyHDAC49759;Homo sapiens (Human)0.78007349
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)0.77927550

[10] CHEMBL535

Original SMILES:
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C

Prepared SMILES:
CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC

P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)3.215551
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)3.03333Known
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)3.01741Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)2.839762
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)2.831083
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)2.644844
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)2.63224Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)2.59886Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)2.57559Known
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)2.45479Known
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)2.401175
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)2.364086
O76039Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL56792;Homo sapiens (Human)2.276047
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)2.258158
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)2.24719Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)2.20743Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)2.19531Known
Q00537Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK175128;Homo sapiens (Human)2.189349
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)2.18881Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)2.17482Known
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)2.1736210
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)2.16438Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)2.15467Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)2.10991Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.08496Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)2.0104Known
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)2.0012811
O14920Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKB3551;Homo sapiens (Human)1.96412
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)1.9563313
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)1.951314
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)1.95099Known
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.9055115
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.90512Known
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)1.8998716
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)1.8808417
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)1.88063Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)1.88032Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)1.87646Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)1.84297Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)1.83492Known
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)1.8339118
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.83319Known
Q96Q40Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1565061;Homo sapiens (Human)1.8312619
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)1.8223320
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)1.8173821
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)1.79969Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.78818Known
P54756Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA52044;Homo sapiens (Human)1.78372Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)1.77818Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)1.77679Known
Q13976cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG15592;Homo sapiens (Human)1.754522
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)1.75188Known
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)1.74779Known
Q9UQ88Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK11A728642;Homo sapiens (Human)1.7419623
Q15375Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA72045;Homo sapiens (Human)1.7413924
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.7365Known
Q9Y463Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1B9149;Homo sapiens (Human)1.7177725
P78368Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G21455;Homo sapiens (Human)1.71376Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)1.7121226
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)1.7110627
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.7047128
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)1.700729
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)1.69616Known
Q8TD08Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15225689;Homo sapiens (Human)1.692230
P546465'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA25563;Homo sapiens (Human)1.69033Known
Q00535Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK51020;Homo sapiens (Human)1.68504Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)1.6668531
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)1.66444Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)1.66232Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)1.65743Known
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)1.65135Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)1.64454Known
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)1.64408Known
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)1.63849Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)1.63816Known
P21127Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK11B984;Homo sapiens (Human)1.6336532
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)1.63037Known
Q9UEE5Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17A9263;Homo sapiens (Human)1.62111Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)1.61924Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)1.61764Known
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.61472Known
P29323Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB22048;Homo sapiens (Human)1.6016433
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)1.59666Known
Q13237cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG25593;Homo sapiens (Human)1.5945234
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)1.58937Known
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.5859435
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.58206Known
Q99755Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC ...PIP5K1A8394;Homo sapiens (Human)1.5802436
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.57667Known
P31751RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT2208;Homo sapiens (Human)1.570637
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)1.56513Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)1.56359Known
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)1.5457838
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)1.54192Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)1.53051Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.52711Known
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.52243Known
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)1.52147Known
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)1.5164239
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)1.51358Known
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.5122Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)1.50321Known
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)1.49913Known
Q8WTQ7Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK7131890;Homo sapiens (Human)1.4916Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)1.49091Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)1.48709Known
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.4838640
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)1.48218Known
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)1.4816641
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.47807Known
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)1.45487Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)1.45409Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.45015Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.44723Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)1.44341Known
Q9NWT8Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, ...Mitochondrion-specific ribosomal protein mS38 familyAURKAIP154998;Homo sapiens (Human)1.4352842
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)1.43195Known
P54764Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA42043;Homo sapiens (Human)1.4242643
Q16816Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG15260;Homo sapiens (Human)1.42391Known
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)1.42355Known
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)1.4176844
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)1.4162145
O00311Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamilyCDC78317;Homo sapiens (Human)1.4094846
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)1.40615Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.404Known
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)1.4003647
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)1.3976448
Q02156Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCE5581;Homo sapiens (Human)1.3961549
Q9BRS2Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK183732;Homo sapiens (Human)1.39009Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)1.38479Known
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)1.38175Known
Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK18737;Homo sapiens (Human)1.3803650
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)1.37939Known
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)1.36779Known
P14616Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSRR3645;Homo sapiens (Human)1.35527Known
Q9BVS4Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK255781;Homo sapiens (Human)1.34548Known
O75914Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK35063;Homo sapiens (Human)1.34102Known
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)1.33771Known
Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)1.32958Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)1.3229Known
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)1.31958Known
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)1.31317Known
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.30888Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)1.3057Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)1.30522Known
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)1.29744Known
Q13523Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familyPRPF4B8899;Homo sapiens (Human)1.28254Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)1.27933Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)1.27398Known
P49674Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1E102800317;1454;Homo sapiens (Human)1.27246Known
Q52WX2Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySBK1388228;Homo sapiens (Human)1.27176Known
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.25443Known
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)1.25232Known
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)1.25093Known
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)1.24072Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)1.23925Known
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)1.23668Known
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)1.23488Known
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.22852Known
P78356Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2B8396;Homo sapiens (Human)1.22654Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.22278Known
P80370Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen ...DLK18788;Homo sapiens (Human)1.21954Known
O94921Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK145218;Homo sapiens (Human)1.21014Known
P57078Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK4Homo sapiens (Human)1.20621Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)1.19487Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)1.19014Known
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.18823Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.1813Known
P48730Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein ...Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1D1453;Homo sapiens (Human)1.18121Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.17194Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)1.16597Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.16435Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.15792Known
P78362SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK26733;Homo sapiens (Human)1.15589Known
Q13627Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1A1859;Homo sapiens (Human)1.14574Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.14219Known
P48729Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A11452;Homo sapiens (Human)1.13852Known
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.1268Known
P17252Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCA5578;Homo sapiens (Human)1.12522Known
Q07002Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK185129;Homo sapiens (Human)1.12199Known
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)1.11513Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)1.115Known
Q15831Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamilySTK116794;Homo sapiens (Human)1.10867Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)1.10295Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)1.08368Known
Q96SB4SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK16732;Homo sapiens (Human)1.08294Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)1.08214Known
Q15835Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK16011;Homo sapiens (Human)1.06644Known
Q9Y2H9Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)Protein kinase superfamily, AGC Ser/Thr protein kinase familyMAST122983;Homo sapiens (Human)1.05442Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)1.05344Known
Q86YV6Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4340156;Homo sapiens (Human)1.05237Known
Q13557Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2D817;Homo sapiens (Human)1.04374Known
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)1.04332Known
Q9P286Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK557144;Homo sapiens (Human)1.03983Known
Q9NRM7Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS226524;Homo sapiens (Human)1.02826Known
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)1.02767Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.02355Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)1.01636Known
Q9UEW8STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK3927347;Homo sapiens (Human)1.00787Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)1.0044Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)0.998007Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)0.993415Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)0.987108Known
O94768Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17B9262;Homo sapiens (Human)0.985089Known
O15111Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyCHUK1147;Homo sapiens (Human)0.964984Known
P42679Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic ...Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyMATK4145;Homo sapiens (Human)0.961777Known
Q6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein ...Protein kinase superfamily, Ser/Thr protein kinase familyDSTYK25778;Homo sapiens (Human)0.958034Known
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)0.945944Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)0.945571Known
P45985Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K46416;Homo sapiens (Human)0.944117Known
Q15139Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD15587;Homo sapiens (Human)0.941625Known
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)0.909249Known
Q9Y6E0Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK248428;Homo sapiens (Human)0.898144Known
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)0.885732Known
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)0.867932Known
O43172U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP ...PRPF49128;Homo sapiens (Human)0.860418Known
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)0.853882Known
Q92772Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL28999;Homo sapiens (Human)0.846318Known
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)0.841236Known
Q9H1R3Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK285366;Homo sapiens (Human)0.834295Known
Q9NRH2SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familySNRK54861;Homo sapiens (Human)0.824339Known
Q9BUB5MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK18569;Homo sapiens (Human)0.815841Known
Q96BR1Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK3100533105;23678;Homo sapiens (Human)0.801397Known
P0C264Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family ...Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamilySBK3100130827;Homo sapiens (Human)0.783967Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)0.779909Known
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)0.75336Known
P27448MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK34140;Homo sapiens (Human)0.734065Known
Q9C098Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK385443;Homo sapiens (Human)0.719378Known
P22303Acetylcholinesterase (AChE) (EC 3.1.1.7)Type-B carboxylesterase/lipase familyACHE43;Homo sapiens (Human)0.712819Known
Q92630Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK28445;Homo sapiens (Human)0.702962Known
P57058Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyHUNK30811;Homo sapiens (Human)0.654082Known
O95747Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyOXSR19943;Homo sapiens (Human)0.65309Known
Q8NFD2Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyANKK1255239;Homo sapiens (Human)0.635073Known
Q13164Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK75598;Homo sapiens (Human)0.616871Known
Q8IY84Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyNIM1K167359;Homo sapiens (Human)0.608448Known
O75460Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyERN12081;Homo sapiens (Human)0.602268Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)0.601646Known
Q9Y6M4Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G31456;Homo sapiens (Human)0.590375Known
Q7KZI7Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK22011;Homo sapiens (Human)0.586935Known
Q6ZN16Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K15389840;Homo sapiens (Human)0.586288Known
Q9H2K2Poly [ADP-ribose] polymerase tankyrase-2 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) ...TNKS280351;Homo sapiens (Human)0.584448Known
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2A815;Homo sapiens (Human)0.571856Known
Q96NX5Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1G57172;Homo sapiens (Human)0.55985Known
P53355Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK11612;Homo sapiens (Human)0.557622Known
Q9UIK4Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK223604;Homo sapiens (Human)0.522616Known
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)0.515797Known
Q9Y6R4Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K44216;Homo sapiens (Human)0.510005Known
Q13555Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2G818;Homo sapiens (Human)0.48712Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)0.484341Known
Q15208Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySTK3811329;Homo sapiens (Human)0.482462Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)0.460775Known
Q9NQU5Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK6106821730;56924;Homo sapiens (Human)0.454471Known
Q8NEV4Myosin-IIIa (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3A53904;Homo sapiens (Human)0.433616Known
Q9NYY3Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK210769;Homo sapiens (Human)0.430801Known
P51955Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK24751;Homo sapiens (Human)0.428223Known
P52564Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K65608;Homo sapiens (Human)0.401292Known
O00506Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2510494;Homo sapiens (Human)0.321304Known
Q12809Potassium voltage-gated channel subfamily H member 2 (Eag homolog) (Ether-a-go-go-related ...Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.1/KCNH2 sub-subfamilyKCNH23757;Homo sapiens (Human)0.22685Known
O15245Solute carrier family 22 member 1 (Organic cation transporter 1) ...Major facilitator (TC 2.A.1) superfamily, Organic cation transporter (TC 2.A.1.19) ...SLC22A16580;Homo sapiens (Human)0.163489Known

[11] CHEMBL475251

Original SMILES:
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC

Prepared SMILES:
COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC

Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)3.79091
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)3.48562Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)3.39565Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)3.24438Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)3.14681Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)3.07502Known
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)2.98064Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)2.74217Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)2.73071Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)2.67994Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)2.67391Known
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)2.66122Known
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)2.64098Known
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)2.616922
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)2.60443Known
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)2.59731Known
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)2.57573Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)2.57431Known
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)2.55244Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)2.51925Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)2.4996Known
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)2.48872Known
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)2.43773Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)2.4048Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)2.39763Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)2.3785Known
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)2.37265Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)2.36807Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)2.36268Known
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)2.35521Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)2.34444Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)2.34163Known
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)2.3389Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)2.33014Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)2.31776Known
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)2.30855Known
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)2.30661Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)2.292783
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)2.28864Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)2.259394
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)2.25628Known
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)2.24555Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)2.24272Known
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)2.22666Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)2.22064Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)2.207Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)2.19305Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)2.18318Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)2.17968Known
O75914Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK35063;Homo sapiens (Human)2.16876Known
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)2.16347Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)2.1452Known
P51679C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) ...G-protein coupled receptor 1 familyCCR41233;Homo sapiens (Human)2.142465
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)2.13965Known
Q13164Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK75598;Homo sapiens (Human)2.138686
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)2.09861Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)2.08898Known
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)2.06747Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.06219Known
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)2.04661Known
Q9C098Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK385443;Homo sapiens (Human)2.04235Known
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)2.03824Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)2.03457Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)2.02767
Q9NYY3Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK210769;Homo sapiens (Human)2.02516Known
Q00537Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK175128;Homo sapiens (Human)2.02361Known
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)2.02131Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)2.01902Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)2.0144Known
O00311Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamilyCDC78317;Homo sapiens (Human)2.00931Known
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)1.99204Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.9904Known
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)1.98847Known
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)1.98806Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.986Known
Q9BXA7Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK1B83942;Homo sapiens (Human)1.98458Known
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)1.97501Known
Q15375Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA72045;Homo sapiens (Human)1.97426Known
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)1.96252Known
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)1.9581Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)1.9519Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)1.94898Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)1.94161Known
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.93333Known
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.93098Known
Q96D53Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase ...Protein kinase superfamily, ADCK protein kinase familyCOQ8B79934;Homo sapiens (Human)1.91694Known
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)1.89539Known
O15146Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase familyMUSK4593;Homo sapiens (Human)1.892Known
P14616Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSRR3645;Homo sapiens (Human)1.85156Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)1.84872Known
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)1.84218Known
Q96L34MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK457787;Homo sapiens (Human)1.83351Known
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.83174Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)1.82074Known
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)1.81862Known
P24723Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCH5583;Homo sapiens (Human)1.813858
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)1.8052Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)1.791589
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)1.78294Known
O94768Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17B9262;Homo sapiens (Human)1.78081Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)1.769610
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)1.76695Known
Q52WX2Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySBK1388228;Homo sapiens (Human)1.76587Known
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.7547Known
P53355Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK11612;Homo sapiens (Human)1.75196Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)1.7407411
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.73464Known
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.7256Known
P29323Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB22048;Homo sapiens (Human)1.72543Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)1.71587Known
P42680Tyrosine-protein kinase Tec (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTEC7006;Homo sapiens (Human)1.71216Known
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)1.70469Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)1.69819Known
Q9UIK4Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK223604;Homo sapiens (Human)1.69107Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)1.68782Known
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)1.67474Known
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)1.67421Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)1.67407Known
Q16816Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG15260;Homo sapiens (Human)1.6695412
Q9Y2K2Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK323387;Homo sapiens (Human)1.6573513
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)1.65604Known
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)1.6501714
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)1.6448515
O94921Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK145218;Homo sapiens (Human)1.6401416
Q00535Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK51020;Homo sapiens (Human)1.6327Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)1.63142Known
Q9NWT8Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, ...Mitochondrion-specific ribosomal protein mS38 familyAURKAIP154998;Homo sapiens (Human)1.6274317
O14920Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKB3551;Homo sapiens (Human)1.62354Known
P04049RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyRAF15894;Homo sapiens (Human)1.61987Known
Q00526Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK31018;Homo sapiens (Human)1.6165918
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.61312Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)1.60776Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)1.60692Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)1.60569Known
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.60568Known
P53671LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK23985;Homo sapiens (Human)1.60451Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.60151Known
P42338Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) ...PI3/PI4-kinase familyPIK3CB5291;Homo sapiens (Human)1.5946619
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.5904920
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)1.58847Known
O15111Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyCHUK1147;Homo sapiens (Human)1.58713Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)1.5869Known
P54764Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA42043;Homo sapiens (Human)1.58593Known
Q8TD08Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15225689;Homo sapiens (Human)1.5813Known
P28482Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15594;Homo sapiens (Human)1.5764421
Q8TD19Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK991754;Homo sapiens (Human)1.57067Known
Q13557Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2D817;Homo sapiens (Human)1.56919Known
Q9P286Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK557144;Homo sapiens (Human)1.5677Known
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)1.56067Known
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.55481Known
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)1.55Known
Q13627Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1A1859;Homo sapiens (Human)1.54023Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)1.53641Known
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)1.53406Known
Q02779Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K104294;Homo sapiens (Human)1.53359Known
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)1.5334322
Q13555Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2G818;Homo sapiens (Human)1.5303Known
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)1.52591Known
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)1.52182Known
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)1.52169Known
P37023Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVRL194;Homo sapiens (Human)1.5109923
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.51065Known
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.4962624
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)1.49528Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.4845825
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.480726
Q15759Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK115600;Homo sapiens (Human)1.4684227
P17252Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCA5578;Homo sapiens (Human)1.4667128
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.4638929
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)1.46322Known
Q00532Cyclin-dependent kinase-like 1 (EC 2.7.11.22) (Protein kinase p42 KKIALRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL18814;Homo sapiens (Human)1.45978Known
P0C1S8Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) ...Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE2494551;Homo sapiens (Human)1.44847Known
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.44513Known
P48736Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) ...PI3/PI4-kinase familyPIK3CG5294;Homo sapiens (Human)1.4431830
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)1.44312Known
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.43666Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)1.43574Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)1.43405Known
P27448MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK34140;Homo sapiens (Human)1.43269Known
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.42999Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.42915Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.41659Known
Q15569Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyTESK17016;Homo sapiens (Human)1.40649Known
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)1.4055131
P53350Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK15347;Homo sapiens (Human)1.4044Known
P37173TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR27048;Homo sapiens (Human)1.4027Known
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)1.40268Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)1.39284Known
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)1.38515Known
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)1.38087Known
P54756Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA52044;Homo sapiens (Human)1.37498Known
P0C264Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family ...Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamilySBK3100130827;Homo sapiens (Human)1.37127Known
Q9P0L2Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK14139;Homo sapiens (Human)1.37025Known
Q9Y5Y9Sodium channel protein type 10 subunit alpha (Peripheral nerve sodium ...Sodium channel (TC 1.A.1.10) family, Nav1.8/SCN10A subfamilySCN10A6336;Homo sapiens (Human)1.3551532
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)1.35Known
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.3487733
Q13705Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2B93;Homo sapiens (Human)1.346334
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)1.3425Known
Q8N568Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK2166614;Homo sapiens (Human)1.3405335
P51955Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK24751;Homo sapiens (Human)1.33965Known
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)1.33632Known
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)1.33045Known
Q07002Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK185129;Homo sapiens (Human)1.3291836
P49761Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK31198;Homo sapiens (Human)1.32343Known
Q9BX84Transient receptor potential cation channel subfamily M member 6 (EC ...Protein kinase superfamily, Alpha-type protein kinase family, ALPK subfamily; Transient ...TRPM6140803;Homo sapiens (Human)1.3214737
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)1.31789Known
Q9UBE8Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...NLK51701;Homo sapiens (Human)1.3149538
Q13237cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG25593;Homo sapiens (Human)1.31484Known
P54753Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB32049;Homo sapiens (Human)1.3104539
Q15139Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD15587;Homo sapiens (Human)1.308740
Q8TDX7Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK7140609;Homo sapiens (Human)1.3064Known
Q00534Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK61021;Homo sapiens (Human)1.3055341
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)1.2957842
P36896Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR1B91;Homo sapiens (Human)1.29087Known
P30291Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE17465;Homo sapiens (Human)1.28279Known
Q92772Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL28999;Homo sapiens (Human)1.28055Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)1.27739Known
Q9NRP7Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)Protein kinase superfamily, Ser/Thr protein kinase familySTK3627148;Homo sapiens (Human)1.27256Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.27117Known
P25101Endothelin-1 receptor (Endothelin receptor type A) (ET-A) (ETA-R) (hET-AR)G-protein coupled receptor 1 family, Endothelin receptor subfamily, EDNRA sub-subfamilyEDNRA1909;Homo sapiens (Human)1.2642643
P51957Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK46787;Homo sapiens (Human)1.26254Known
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)1.25913Known
Q9HC98Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK610783;Homo sapiens (Human)1.25275Known
P45985Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K46416;Homo sapiens (Human)1.25218Known
P41240Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyCSK1445;Homo sapiens (Human)1.2479Known
P28845Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC 1.1.1.146) (11-beta-hydroxysteroid dehydrogenase 1) (11-DH) ...Short-chain dehydrogenases/reductases (SDR) familyHSD11B13290;Homo sapiens (Human)1.2442344
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)1.24014Known
Q59H18Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase ...TNNI3K100526835;51086;Homo sapiens (Human)1.23893Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)1.23249Known
P78356Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2B8396;Homo sapiens (Human)1.23111Known
O15075Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK19201;Homo sapiens (Human)1.2303145
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)1.22944Known
P62937Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) ...Cyclophilin-type PPIase family, PPIase A subfamilyPPIA5478;Homo sapiens (Human)1.2188846
Q8IW41MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMAPKAPK58550;Homo sapiens (Human)1.2159347
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)1.21302Known
P27986Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K ...PI3K p85 subunit familyPIK3R15295;Homo sapiens (Human)1.2129948
P19525Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK25610;Homo sapiens (Human)1.20911Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)1.20152Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.19617Known
Q9BRS2Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK183732;Homo sapiens (Human)1.19592Known
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)1.19523Known
Q6P3R8Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK5341676;Homo sapiens (Human)1.19229Known
P48729Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A11452;Homo sapiens (Human)1.1797649
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)1.17799Known
P546465'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA25563;Homo sapiens (Human)1.17087Known
P48730Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein ...Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1D1453;Homo sapiens (Human)1.1603950
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.14788Known
Q8TBX8Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2C79837;Homo sapiens (Human)1.14614Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)1.13913Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.1367Known
O14730Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK38780;Homo sapiens (Human)1.1328Known
Q9UEE5Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17A9263;Homo sapiens (Human)1.12867Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)1.12737Known
Q8WU08Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySTK32A202374;Homo sapiens (Human)1.12311Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)1.11778Known
Q7KZI7Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK22011;Homo sapiens (Human)1.1056Known
Q9Y6R4Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K44216;Homo sapiens (Human)1.10343Known
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2A815;Homo sapiens (Human)1.09511Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.09267Known
Q13177Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK25062;Homo sapiens (Human)1.0819Known
O00329Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) ...PI3/PI4-kinase familyPIK3CD5293;Homo sapiens (Human)1.07863Known
P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR17046;Homo sapiens (Human)1.07603Known
Q86YV6Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4340156;Homo sapiens (Human)1.06373Known
Q9BUB5MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK18569;Homo sapiens (Human)1.06283Known
Q9UKI8Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyTLK19874;Homo sapiens (Human)1.06095Known
Q15835Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK16011;Homo sapiens (Human)1.04655Known
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)1.04552Known
Q9H4B4Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK31263;Homo sapiens (Human)1.04444Known
Q16512Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN15585;Homo sapiens (Human)1.0363Known
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)1.03176Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)1.02851Known
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)1.01491Known
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)1.01038Known
Q8WTQ7Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK7131890;Homo sapiens (Human)0.998827Known
Q96PY6Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK14750;Homo sapiens (Human)0.994728Known
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)0.986342Known
P43403Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) ...Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilyZAP707535;Homo sapiens (Human)0.976776Known
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)0.970519Known
Q96SB4SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK16732;Homo sapiens (Human)0.957287Known
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)0.955426Known
Q14012Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK18536;Homo sapiens (Human)0.950981Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)0.94974Known
Q8NG66Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK1179858;Homo sapiens (Human)0.941666Known
Q9NR20Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK48798;Homo sapiens (Human)0.939519Known
O75460Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyERN12081;Homo sapiens (Human)0.92831Known
Q9UBF8Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) ...PI3/PI4-kinase family, Type III PI4K subfamilyPI4KB5298;Homo sapiens (Human)0.926215Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)0.914482Known
O60331Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC ...PIP5K1C23396;Homo sapiens (Human)0.889716Known
O95747Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyOXSR19943;Homo sapiens (Human)0.884675Known
O14578Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)Protein kinase superfamily, AGC Ser/Thr protein kinase familyCIT11113;Homo sapiens (Human)0.875764Known
Q99755Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC ...PIP5K1A8394;Homo sapiens (Human)0.849105Known
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)0.848574Known
P51956Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (HSPK 36) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK34752;Homo sapiens (Human)0.844906Known
Q15831Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamilySTK116794;Homo sapiens (Human)0.832822Known
P53778Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK126300;Homo sapiens (Human)0.831721Known
P57078Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK4Homo sapiens (Human)0.801741Known
Q05655Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCD5580;Homo sapiens (Human)0.796804Known
P52564Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K65608;Homo sapiens (Human)0.775115Known
P22694cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACB5567;Homo sapiens (Human)0.762331Known
Q92630Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK28445;Homo sapiens (Human)0.742586Known
Q9BVS4Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK255781;Homo sapiens (Human)0.741797Known
P05129Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCG5582;Homo sapiens (Human)0.708354Known
O15264Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK135603;Homo sapiens (Human)0.668169Known
Q86UE8Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase ...Protein kinase superfamily, Ser/Thr protein kinase familyTLK211011;Homo sapiens (Human)0.667705Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)0.66654Known
Q8NI60Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 ...Protein kinase superfamily, ADCK protein kinase familyCOQ8A56997;Homo sapiens (Human)0.658287Known
Q8NFD2Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyANKK1255239;Homo sapiens (Human)0.638169Known
Q96NX5Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1G57172;Homo sapiens (Human)0.635514Known
Q13153Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK15058;Homo sapiens (Human)0.627159Known
Q8IY84Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyNIM1K167359;Homo sapiens (Human)0.578964Known
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)0.575Known
Q9NQU5Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK6106821730;56924;Homo sapiens (Human)0.562666Known
Q15208Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySTK3811329;Homo sapiens (Human)0.51245Known
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)0.502645Known
Q9NRM7Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS226524;Homo sapiens (Human)0.345227Known
O00506Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2510494;Homo sapiens (Human)0.215256Known

[13] CHEMBL1908397

Original SMILES:
O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1

Prepared SMILES:
O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1

O76039Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL56792;Homo sapiens (Human)3.159641
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)3.06988Known
P31645Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family ...Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamilySLC6A46532;Homo sapiens (Human)2.973752
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)2.9092Known
P31749RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT1207;Homo sapiens (Human)2.888883
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)2.854214
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)2.68022Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)2.58505Known
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)2.479645
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)2.42003Known
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)2.41764Known
Q00537Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK175128;Homo sapiens (Human)2.37176Known
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)2.339556
O14936Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; ...CASK8573;Homo sapiens (Human)2.333767
Q9P0L2Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK14139;Homo sapiens (Human)2.3264Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)2.32133Known
Q13627Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1A1859;Homo sapiens (Human)2.31604Known
P11309Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM15292;Homo sapiens (Human)2.284328
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)2.27075Known
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)2.27056Known
P45985Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K46416;Homo sapiens (Human)2.24899Known
O75914Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK35063;Homo sapiens (Human)2.22806Known
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)2.21137Known
Q96L34MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK457787;Homo sapiens (Human)2.1995Known
Q16816Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG15260;Homo sapiens (Human)2.19506Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)2.18162Known
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)2.17886Known
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)2.173369
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)2.16562Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)2.1541Known
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)2.14373Known
Q13237cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG25593;Homo sapiens (Human)2.14218Known
Q9P286Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK557144;Homo sapiens (Human)2.14015Known
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)2.13515Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)2.12985Known
Q15835Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK16011;Homo sapiens (Human)2.1277310
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)2.1179Known
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)2.1118311
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)2.10964Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)2.10956Known
Q99755Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC ...PIP5K1A8394;Homo sapiens (Human)2.06741Known
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)2.06293Known
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)2.05293Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)2.02324Known
P27448MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK34140;Homo sapiens (Human)2.02168Known
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)2.01976Known
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)2.01551Known
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)2.0135912
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)2.00725Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)1.99569Known
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)1.9856813
P78362SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK26733;Homo sapiens (Human)1.98448Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)1.98322Known
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)1.97541Known
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)1.97315Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)1.96477Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)1.95129Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)1.9494Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.94302Known
O94921Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK145218;Homo sapiens (Human)1.93865Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)1.92898Known
Q04759Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCQ5588;Homo sapiens (Human)1.8986214
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)1.8963715
Q15139Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD15587;Homo sapiens (Human)1.89581Known
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)1.89107Known
Q13164Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK75598;Homo sapiens (Human)1.88782Known
Q9UBE8Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...NLK51701;Homo sapiens (Human)1.8862716
Q02779Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K104294;Homo sapiens (Human)1.88355Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)1.87842Known
Q9Y463Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1B9149;Homo sapiens (Human)1.87775Known
Q9NWT8Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, ...Mitochondrion-specific ribosomal protein mS38 familyAURKAIP154998;Homo sapiens (Human)1.8704417
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)1.86985Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)1.86755Known
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)1.85189Known
O15111Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyCHUK1147;Homo sapiens (Human)1.85038Known
P24723Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCH5583;Homo sapiens (Human)1.8499218
Q9Y2K2Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK323387;Homo sapiens (Human)1.8483Known
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)1.8367619
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)1.83387Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)1.83238Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)1.83037Known
Q52WX2Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySBK1388228;Homo sapiens (Human)1.82911Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)1.81323Known
P546465'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA25563;Homo sapiens (Human)1.80703Known
Q9BXA7Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK1B83942;Homo sapiens (Human)1.80377Known
Q9UQ88Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK11A728642;Homo sapiens (Human)1.8013520
P0C264Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family ...Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamilySBK3100130827;Homo sapiens (Human)1.78396Known
Q9Y243RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT310000;Homo sapiens (Human)1.7756921
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)1.77566Known
Q15759Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK115600;Homo sapiens (Human)1.77521Known
P52564Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K65608;Homo sapiens (Human)1.77459Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)1.77439Known
Q13554Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2B816;Homo sapiens (Human)1.7553522
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.74771Known
P78356Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2B8396;Homo sapiens (Human)1.74464Known
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)1.74396Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.72711Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)1.723523
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.71832Known
Q8TD08Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15225689;Homo sapiens (Human)1.71271Known
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)1.7120924
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)1.70973Known
Q6ZN16Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K15389840;Homo sapiens (Human)1.7053925
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.69389Known
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)1.69388Known
Q9C098Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK385443;Homo sapiens (Human)1.68807Known
P51817cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKX5613;Homo sapiens (Human)1.68794Known
P42680Tyrosine-protein kinase Tec (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTEC7006;Homo sapiens (Human)1.6872626
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)1.68228Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)1.66432Known
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)1.6620727
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.65958Known
Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK18737;Homo sapiens (Human)1.65433Known
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)1.65178Known
O00506Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2510494;Homo sapiens (Human)1.64578Known
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)1.6338628
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)1.63286Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)1.61666Known
P21127Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK11B984;Homo sapiens (Human)1.6147529
O14578Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)Protein kinase superfamily, AGC Ser/Thr protein kinase familyCIT11113;Homo sapiens (Human)1.61265Known
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.605Known
P22694cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACB5567;Homo sapiens (Human)1.5990530
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)1.5985Known
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.59782Known
Q9BRS2Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK183732;Homo sapiens (Human)1.59429Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)1.5878Known
Q9NQU5Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK6106821730;56924;Homo sapiens (Human)1.58488Known
P17252Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCA5578;Homo sapiens (Human)1.5817431
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)1.57965Known
Q8IWQ3Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK29024;Homo sapiens (Human)1.57891Known
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.5738Known
P31751RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT2208;Homo sapiens (Human)1.5711432
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)1.57058Known
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)1.56879Known
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)1.56869Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)1.56347Known
O14730Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK38780;Homo sapiens (Human)1.56314Known
P57078Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK4Homo sapiens (Human)1.55536Known
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)1.55511Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)1.55366Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)1.54292Known
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.53293Known
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.52633Known
Q15831Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamilySTK116794;Homo sapiens (Human)1.52134Known
Q9Y2H9Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)Protein kinase superfamily, AGC Ser/Thr protein kinase familyMAST122983;Homo sapiens (Human)1.5171933
Q9UEE5Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17A9263;Homo sapiens (Human)1.51071Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)1.50231Known
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)1.48951Known
P0DMS8Adenosine receptor A3G-protein coupled receptor 1 familyADORA3140;Homo sapiens (Human)1.4860134
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)1.48465Known
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)1.48246Known
O94768Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17B9262;Homo sapiens (Human)1.48051Known
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.46215Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)1.4591Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)1.45906Known
P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR17046;Homo sapiens (Human)1.4587935
Q13523Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familyPRPF4B8899;Homo sapiens (Human)1.45578Known
Q9H1R3Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK285366;Homo sapiens (Human)1.45238Known
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.44694Known
P23975Sodium-dependent noradrenaline transporter (Norepinephrine transporter) (NET) (Solute carrier family 6 ...Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A2 subfamilySLC6A26530;Homo sapiens (Human)1.4413936
Q8NEV4Myosin-IIIa (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3A53904;Homo sapiens (Human)1.42668Known
Q8NFD2Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyANKK1255239;Homo sapiens (Human)1.42661Known
Q96Q40Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1565061;Homo sapiens (Human)1.41951Known
Q07002Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK185129;Homo sapiens (Human)1.4152937
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.41509Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)1.4141538
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)1.4046Known
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)1.39987Known
Q59H18Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase ...TNNI3K100526835;51086;Homo sapiens (Human)1.3980839
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2A815;Homo sapiens (Human)1.39794Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)1.39455Known
O00329Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) ...PI3/PI4-kinase familyPIK3CD5293;Homo sapiens (Human)1.3766940
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)1.37612Known
O15075Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK19201;Homo sapiens (Human)1.37324Known
P11511Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen ...Cytochrome P450 familyCYP19A11588;Homo sapiens (Human)1.3709741
Q00526Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK31018;Homo sapiens (Human)1.3703642
Q9UEW8STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK3927347;Homo sapiens (Human)1.35908Known
P14616Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSRR3645;Homo sapiens (Human)1.35639Known
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.35173Known
Q7KZI7Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK22011;Homo sapiens (Human)1.35032Known
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.345Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)1.34418Known
Q13555Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2G818;Homo sapiens (Human)1.3420343
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)1.34018Known
Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)1.3398344
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)1.33766Known
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)1.33617Known
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)1.33077Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.32582Known
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)1.3248945
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)1.32436Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)1.32422Known
Q13153Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK15058;Homo sapiens (Human)1.32184Known
O15146Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase familyMUSK4593;Homo sapiens (Human)1.32184Known
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.3191Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.31648Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)1.31468Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)1.31452Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)1.3128Known
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)1.31052Known
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)1.30936Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)1.30857Known
Q16512Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN15585;Homo sapiens (Human)1.29814Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)1.29634Known
Q15208Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySTK3811329;Homo sapiens (Human)1.28504Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.2835Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)1.27968Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)1.27372Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)1.27288Known
Q8WTQ7Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK7131890;Homo sapiens (Human)1.27144Known
P36896Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR1B91;Homo sapiens (Human)1.2694346
Q9BQI3Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK127102;Homo sapiens (Human)1.2652947
P09874Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like ...PARP1142;Homo sapiens (Human)1.2621348
P42336Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) ...PI3/PI4-kinase familyPIK3CA5290;Homo sapiens (Human)1.2509449
Q6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein ...Protein kinase superfamily, Ser/Thr protein kinase familyDSTYK25778;Homo sapiens (Human)1.24746Known
P57058Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyHUNK30811;Homo sapiens (Human)1.24714Known
P43403Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) ...Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilyZAP707535;Homo sapiens (Human)1.24542Known
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)1.2434150
Q86UE8Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase ...Protein kinase superfamily, Ser/Thr protein kinase familyTLK211011;Homo sapiens (Human)1.23246Known
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)1.22349Known
P49761Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK31198;Homo sapiens (Human)1.21677Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.2064Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.20506Known
Q13177Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK25062;Homo sapiens (Human)1.19982Known
Q8WU08Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySTK32A202374;Homo sapiens (Human)1.19918Known
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.19829Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)1.19469Known
Q9P289Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2651765;Homo sapiens (Human)1.19462Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)1.1914Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.19014Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)1.18837Known
Q9Y6E0Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK248428;Homo sapiens (Human)1.18584Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)1.18571Known
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)1.18324Known
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)1.18027Known
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)1.17917Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)1.17607Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)1.16308Known
Q15375Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA72045;Homo sapiens (Human)1.14888Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)1.14649Known
P49674Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1E102800317;1454;Homo sapiens (Human)1.13773Known
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)1.13311Known
O95747Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyOXSR19943;Homo sapiens (Human)1.13213Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)1.12609Known
P48729Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A11452;Homo sapiens (Human)1.12422Known
Q9NRM7Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS226524;Homo sapiens (Human)1.11466Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)1.11215Known
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.11138Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)1.10583Known
Q8IW41MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMAPKAPK58550;Homo sapiens (Human)1.10432Known
P78368Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G21455;Homo sapiens (Human)1.10334Known
Q9UKI8Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyTLK19874;Homo sapiens (Human)1.09421Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.09393Known
Q09013Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyDMPK1760;Homo sapiens (Human)1.09341Known
Q96SB4SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK16732;Homo sapiens (Human)1.091Known
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)1.08338Known
Q86YV6Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4340156;Homo sapiens (Human)1.08029Known
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)1.07823Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)1.07807Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)1.07499Known
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)1.07259Known
Q92772Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL28999;Homo sapiens (Human)1.07112Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.06467Known
P41240Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyCSK1445;Homo sapiens (Human)1.0372Known
Q92630Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK28445;Homo sapiens (Human)1.0362Known
Q8WXR4Myosin-IIIb (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3B140469;Homo sapiens (Human)1.02939Known
Q9UIK4Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK223604;Homo sapiens (Human)1.02802Known
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)1.0214Known
O75460Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyERN12081;Homo sapiens (Human)1.00595Known
Q9Y2H1Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySTK38L23012;Homo sapiens (Human)0.999675Known
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)0.997159Known
P53355Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK11612;Homo sapiens (Human)0.991355Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)0.989189Known
P36894Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1A657;Homo sapiens (Human)0.985625Known
P51957Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK46787;Homo sapiens (Human)0.985394Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)0.981321Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)0.976978Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)0.975177Known
O95835Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS19113;Homo sapiens (Human)0.974007Known
Q96BR1Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK3100533105;23678;Homo sapiens (Human)0.97132Known
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)0.960653Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)0.959009Known
Q13976cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG15592;Homo sapiens (Human)0.941645Known
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)0.937618Known
Q8TDC3Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK184446;Homo sapiens (Human)0.910516Known
P48730Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein ...Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1D1453;Homo sapiens (Human)0.909218Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)0.908548Known
Q6DT37Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPG55561;Homo sapiens (Human)0.905433Known
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)0.901557Known
Q9HC98Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK610783;Homo sapiens (Human)0.900312Known
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)0.880364Known
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)0.872335Known
P30291Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE17465;Homo sapiens (Human)0.870938Known
P51955Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK24751;Homo sapiens (Human)0.864448Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)0.852723Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)0.851879Known
Q13705Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2B93;Homo sapiens (Human)0.834018Known
Q8TD19Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK991754;Homo sapiens (Human)0.823716Known
Q9Y6R4Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K44216;Homo sapiens (Human)0.82304Known
Q8TDX7Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK7140609;Homo sapiens (Human)0.815323Known
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)0.807779Known
Q8IY84Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyNIM1K167359;Homo sapiens (Human)0.80255Known
P42679Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic ...Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyMATK4145;Homo sapiens (Human)0.785784Known
Q13873Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR2659;Homo sapiens (Human)0.775397Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)0.748313Known
Q96NX5Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1G57172;Homo sapiens (Human)0.741688Known
Q9HCP0Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G153944;Homo sapiens (Human)0.732084Known
Q96PY6Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK14750;Homo sapiens (Human)0.728878Known
P51956Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (HSPK 36) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK34752;Homo sapiens (Human)0.683503Known
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)0.666522Known
Q9BVS4Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK255781;Homo sapiens (Human)0.643648Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)0.63686Known
Q9Y6M4Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G31456;Homo sapiens (Human)0.615445Known
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)0.586167Known
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)0.580319Known
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)0.569536Known
Q6P3R8Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK5341676;Homo sapiens (Human)0.558825Known
P27037Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2A92;Homo sapiens (Human)0.500746Known
Q14012Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK18536;Homo sapiens (Human)0.442248Known
O14920Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKB3551;Homo sapiens (Human)0.421229Known
Q16659Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK65597;Homo sapiens (Human)0.361921Known
P19525Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK25610;Homo sapiens (Human)0.306054Known
P0C1S8Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) ...Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE2494551;Homo sapiens (Human)0.295944Known

[14] CHEMBL502835

Original SMILES:
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1

Prepared SMILES:
COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C

P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)3.45278Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)3.3181Known
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)3.28398Known
O43603Galanin receptor type 2 (GAL2-R) (GALR-2)G-protein coupled receptor 1 familyGALR28811;Homo sapiens (Human)3.208981
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)3.05501Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)2.92918Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)2.89174Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)2.76989Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)2.71026Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)2.6426Known
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)2.619692
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)2.54677Known
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)2.53119Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)2.49079Known
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)2.45479Known
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)2.39444Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)2.38255Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)2.30545Known
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)2.23983
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)2.21219Known
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)2.21055Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)2.20928Known
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)2.18057Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)2.16715Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)2.16444Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)2.13923Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)2.11623Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)2.10795Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)2.07934Known
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)2.05724Known
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)2.01405Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)1.98712Known
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)1.97212Known
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.96141Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.94937Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)1.92361Known
Q00526Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK31018;Homo sapiens (Human)1.91834
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)1.909875
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.90512Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)1.877356
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.86367Known
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.85949Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)1.84835Known
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)1.84206Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)1.81965Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)1.80704Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.80134Known
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.77811Known
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)1.77696Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)1.77679Known
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.76603Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)1.75188Known
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)1.745417
P546465'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA25563;Homo sapiens (Human)1.73079Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.728338
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)1.72779Known
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)1.71776Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)1.71158Known
P42680Tyrosine-protein kinase Tec (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTEC7006;Homo sapiens (Human)1.711469
Q52WX2Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySBK1388228;Homo sapiens (Human)1.711Known
Q92772Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL28999;Homo sapiens (Human)1.68711Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)1.68534Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)1.68504Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)1.67758Known
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)1.66931Known
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)1.66444Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.66247Known
Q9NWT8Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, ...Mitochondrion-specific ribosomal protein mS38 familyAURKAIP154998;Homo sapiens (Human)1.6453210
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)1.64515Known
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)1.63311
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.630412
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)1.63037Known
Q9UEE5Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17A9263;Homo sapiens (Human)1.62111Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)1.61924Known
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.61472Known
P35372Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid ...G-protein coupled receptor 1 familyOPRM14988;Homo sapiens (Human)1.6030213
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)1.59666Known
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)1.58937Known
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.58232Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.58129Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)1.5790914
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)1.56332Known
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)1.55212Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)1.54192Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.52269Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)1.52235Known
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)1.51554Known
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)1.5141Known
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.51219Known
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)1.51091Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)1.50954Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.50356Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)1.50321Known
P24723Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCH5583;Homo sapiens (Human)1.5012615
Q8TD08Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15225689;Homo sapiens (Human)1.4979816
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)1.49388Known
Q8WTQ7Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK7131890;Homo sapiens (Human)1.4916Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)1.48959Known
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)1.485617
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)1.48218Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)1.46718
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)1.46254Known
Q8IWQ3Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK29024;Homo sapiens (Human)1.459619
Q96L34MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK457787;Homo sapiens (Human)1.45377Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)1.44679Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)1.44336Known
P05771Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCB5579;Homo sapiens (Human)1.4431920
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)1.4383521
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)1.43463Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)1.43321Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.4328922
Q6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein ...Protein kinase superfamily, Ser/Thr protein kinase familyDSTYK25778;Homo sapiens (Human)1.4261623
Q16816Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG15260;Homo sapiens (Human)1.42391Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.42229Known
Q86YV6Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4340156;Homo sapiens (Human)1.40675Known
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)1.4016Known
P53350Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK15347;Homo sapiens (Human)1.400424
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.39612Known
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)1.39111Known
Q9BRS2Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK183732;Homo sapiens (Human)1.39009Known
Q13976cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG15592;Homo sapiens (Human)1.38549Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)1.3818325
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)1.38175Known
Q00537Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK175128;Homo sapiens (Human)1.37562Known
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)1.37171Known
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.3678626
Q9BWU1Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1923097;Homo sapiens (Human)1.3643227
Q13627Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1A1859;Homo sapiens (Human)1.3603528
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.3591Known
P14616Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSRR3645;Homo sapiens (Human)1.35527Known
P36896Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR1B91;Homo sapiens (Human)1.3484Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)1.3438229
O75914Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK35063;Homo sapiens (Human)1.34102Known
Q8TDC3Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK184446;Homo sapiens (Human)1.32530
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)1.31707Known
P32239Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R)G-protein coupled receptor 1 familyCCKBR887;Homo sapiens (Human)1.3166831
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)1.30522Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)1.28999Known
Q07002Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK185129;Homo sapiens (Human)1.28838Known
P11309Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM15292;Homo sapiens (Human)1.2864532
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)1.2827133
Q13523Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familyPRPF4B8899;Homo sapiens (Human)1.28254Known
Q99755Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC ...PIP5K1A8394;Homo sapiens (Human)1.27625Known
P49674Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1E102800317;1454;Homo sapiens (Human)1.27246Known
O15146Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase familyMUSK4593;Homo sapiens (Human)1.26866Known
O15111Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyCHUK1147;Homo sapiens (Human)1.26728Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.2652834
Q9BVS4Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK255781;Homo sapiens (Human)1.2594935
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)1.25838Known
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.25623Known
Q13164Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK75598;Homo sapiens (Human)1.25356Known
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)1.25232Known
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)1.25093Known
Q16566Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK4814;Homo sapiens (Human)1.24787Known
Q9P289Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2651765;Homo sapiens (Human)1.23582Known
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)1.23488Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.23436Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)1.23253Known
Q96BR1Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK3100533105;23678;Homo sapiens (Human)1.22928Known
O14730Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK38780;Homo sapiens (Human)1.22704Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)1.22659Known
P78356Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2B8396;Homo sapiens (Human)1.22654Known
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)1.22508Known
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.22295Known
O14920Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKB3551;Homo sapiens (Human)1.2162136
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)1.21484Known
Q15831Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamilySTK116794;Homo sapiens (Human)1.21449Known
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)1.210137
Q04759Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCQ5588;Homo sapiens (Human)1.20526Known
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)1.20427Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)1.20329Known
P28482Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15594;Homo sapiens (Human)1.1989138
Q9C098Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK385443;Homo sapiens (Human)1.19319Known
P49356Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit ...Protein prenyltransferase subunit beta familyFNTB100529261;2342;Homo sapiens (Human)1.1925739
Q96SB4SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK16732;Homo sapiens (Human)1.18648Known
Q13237cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG25593;Homo sapiens (Human)1.1834640
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)1.17891Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)1.17498Known
Q8N568Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK2166614;Homo sapiens (Human)1.1742341
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)1.1718142
Q9Y2K2Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK323387;Homo sapiens (Human)1.1671443
Q9UEW8STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK3927347;Homo sapiens (Human)1.167Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)1.16409Known
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)1.16224Known
O94768Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17B9262;Homo sapiens (Human)1.15829Known
P78362SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK26733;Homo sapiens (Human)1.15589Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)1.13776Known
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.1268Known
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)1.1251944
P0C264Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family ...Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamilySBK3100130827;Homo sapiens (Human)1.12217Known
P41240Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyCSK1445;Homo sapiens (Human)1.1205645
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)1.1158246
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)1.11513Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)1.115Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.1143547
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)1.10719Known
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)1.10687Known
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)1.104448
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.1037949
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)1.10295Known
O15264Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK135603;Homo sapiens (Human)1.1024750
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)1.09634Known
Q13873Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR2659;Homo sapiens (Human)1.09425Known
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)1.08695Known
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.08568Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)1.07833Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.07543Known
P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR17046;Homo sapiens (Human)1.07329Known
O95747Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyOXSR19943;Homo sapiens (Human)1.07247Known
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)1.07044Known
P57078Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK4Homo sapiens (Human)1.06848Known
Q15835Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK16011;Homo sapiens (Human)1.06644Known
Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK18737;Homo sapiens (Human)1.06032Known
Q9P0L2Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK14139;Homo sapiens (Human)1.05913Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)1.05344Known
Q16512Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN15585;Homo sapiens (Human)1.04442Known
Q9P286Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK557144;Homo sapiens (Human)1.03983Known
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)1.02436Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)1.00534Known
P37023Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVRL194;Homo sapiens (Human)0.990479Known
Q9NRM7Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS226524;Homo sapiens (Human)0.98953Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)0.987108Known
Q9Y6E0Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK248428;Homo sapiens (Human)0.973796Known
Q15139Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD15587;Homo sapiens (Human)0.97115Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)0.969342Known
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)0.951814Known
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)0.945944Known
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)0.941214Known
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)0.909249Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)0.909018Known
Q02779Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K104294;Homo sapiens (Human)0.908528Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)0.897801Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)0.894459Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)0.887152Known
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)0.853743Known
P48730Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein ...Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1D1453;Homo sapiens (Human)0.845438Known
O94921Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK145218;Homo sapiens (Human)0.843609Known
P27448MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK34140;Homo sapiens (Human)0.835965Known
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)0.821118Known
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)0.808682Known
Q9H1R3Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK285366;Homo sapiens (Human)0.806615Known
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)0.791541Known
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)0.776091Known
P45985Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K46416;Homo sapiens (Human)0.763805Known
Q13177Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK25062;Homo sapiens (Human)0.760543Known
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)0.75336Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)0.704808Known
Q8WXR4Myosin-IIIb (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3B140469;Homo sapiens (Human)0.693245Known
Q6ZN16Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K15389840;Homo sapiens (Human)0.689726Known
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2A815;Homo sapiens (Human)0.66837Known
Q14012Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK18536;Homo sapiens (Human)0.665354Known
Q9UIK4Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK223604;Homo sapiens (Human)0.663366Known
Q9Y463Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1B9149;Homo sapiens (Human)0.657847Known
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)0.654645Known
O95835Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS19113;Homo sapiens (Human)0.640179Known
Q96NX5Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1G57172;Homo sapiens (Human)0.638667Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)0.62999Known
Q7KZI7Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK22011;Homo sapiens (Human)0.609971Known
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)0.609571Known
O15075Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK19201;Homo sapiens (Human)0.607888Known
P43403Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) ...Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilyZAP707535;Homo sapiens (Human)0.598874Known
O75460Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyERN12081;Homo sapiens (Human)0.596699Known
Q9Y2H9Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)Protein kinase superfamily, AGC Ser/Thr protein kinase familyMAST122983;Homo sapiens (Human)0.591593Known
Q9BXA7Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK1B83942;Homo sapiens (Human)0.546826Known
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)0.515797Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)0.460774Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)0.454426Known
P30291Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE17465;Homo sapiens (Human)0.444548Known

[15] CHEMBL574738

Original SMILES:
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1

Prepared SMILES:
CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC

P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)3.40336Known
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)3.19141Known
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)3.167441
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)3.155692
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)2.94941Known
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)2.88223Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)2.76281Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.65912Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)2.56577Known
P34913Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) ...AB hydrolase superfamily, Epoxide hydrolase familyEPHX22053;Homo sapiens (Human)2.543793
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)2.529554
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)2.5274Known
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)2.51321Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)2.50627Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)2.464135
Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK18737;Homo sapiens (Human)2.46187Known
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)2.40238Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)2.38947Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)2.37996Known
Q92772Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL28999;Homo sapiens (Human)2.35017Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)2.24747Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)2.2405Known
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)2.221966
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)2.16567Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)2.147947
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)2.14525Known
O14920Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKB3551;Homo sapiens (Human)2.12075Known
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)2.099598
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)2.09108Known
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)2.08976Known
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)2.05686Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)2.047089
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)2.0352810
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)2.03026Known
Q15759Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK115600;Homo sapiens (Human)1.9879911
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)1.98187Known
Q15375Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA72045;Homo sapiens (Human)1.9768112
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)1.97501Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)1.9689313
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)1.9649114
Q00526Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK31018;Homo sapiens (Human)1.95673Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.93167Known
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)1.9222815
Q9BWU1Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1923097;Homo sapiens (Human)1.91969Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)1.90993Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)1.8916316
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.88366Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)1.86116Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.84037Known
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)1.8399317
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)1.81502Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)1.8146818
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)1.8052719
P35462D(3) dopamine receptor (Dopamine D3 receptor)G-protein coupled receptor 1 familyDRD31814;Homo sapiens (Human)1.7858920
P09960Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)Peptidase M1 familyLTA4H4048;Homo sapiens (Human)1.7290721
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.7183922
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.7099523
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)1.7053Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)1.7034Known
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)1.6954324
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.6937625
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.68765Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)1.65788Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.64948Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)1.61171Known
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)1.59466Known
Q8IVW4Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine-protein kinase NKIAMRE)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL351265;Homo sapiens (Human)1.59062Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)1.5893Known
P04049RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyRAF15894;Homo sapiens (Human)1.5692626
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)1.56545Known
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)1.55385Known
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)1.53794Known
P10275Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C ...Nuclear hormone receptor family, NR3 subfamilyAR367;Homo sapiens (Human)1.5365127
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.5319Known
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.51691Known
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)1.50525Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)1.5026Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)1.49212Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)1.4801428
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.47269Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)1.4644Known
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.46139Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.46086Known
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)1.45928Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)1.45504Known
Q00532Cyclin-dependent kinase-like 1 (EC 2.7.11.22) (Protein kinase p42 KKIALRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL18814;Homo sapiens (Human)1.45174Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)1.4418529
P20794Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyMAK4117;Homo sapiens (Human)1.43849Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)1.43464Known
Q07002Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK185129;Homo sapiens (Human)1.43268Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.4281630
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)1.42368Known
O94921Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK145218;Homo sapiens (Human)1.42278Known
P57078Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK4Homo sapiens (Human)1.41215Known
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)1.39966Known
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)1.38821Known
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)1.3836631
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.376Known
O15264Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK135603;Homo sapiens (Human)1.37533Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)1.37001Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)1.3487632
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)1.345233
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)1.34471Known
Q00534Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK61021;Homo sapiens (Human)1.340134
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)1.3354235
P53778Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK126300;Homo sapiens (Human)1.32947Known
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.31506Known
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)1.30963Known
Q9BVS4Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK255781;Homo sapiens (Human)1.30833Known
O14730Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK38780;Homo sapiens (Human)1.3001736
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.3Known
Q96Q40Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1565061;Homo sapiens (Human)1.29342Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.2902Known
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.2878337
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)1.2863538
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)1.2858839
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)1.28245Known
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)1.27739Known
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)1.27497Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)1.27445Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)1.26663Known
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)1.2627540
Q00535Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK51020;Homo sapiens (Human)1.25103Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)1.24985Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)1.23046Known
Q9C098Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK385443;Homo sapiens (Human)1.2254741
P21917D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)G-protein coupled receptor 1 familyDRD41815;Homo sapiens (Human)1.2226442
Q9NWT8Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, ...Mitochondrion-specific ribosomal protein mS38 familyAURKAIP154998;Homo sapiens (Human)1.2214943
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)1.2196Known
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)1.2185644
P49674Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1E102800317;1454;Homo sapiens (Human)1.2129745
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.21188Known
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.20546Known
O15075Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK19201;Homo sapiens (Human)1.2047146
Q9Y2K2Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK323387;Homo sapiens (Human)1.1870547
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)1.18557Known
Q8N568Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK2166614;Homo sapiens (Human)1.1853348
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)1.18459Known
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)1.17865Known
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)1.1750749
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)1.1518650
O14733Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K75609;Homo sapiens (Human)1.1442Known
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.12149Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)1.11271Known
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)1.11029Known
O76039Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL56792;Homo sapiens (Human)1.10571Known
P29323Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB22048;Homo sapiens (Human)1.10547Known
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.10234Known
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)1.09963Known
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.09934Known
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)1.08887Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.07439Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)1.06934Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)1.06011Known
P14616Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSRR3645;Homo sapiens (Human)1.05781Known
Q8TD08Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15225689;Homo sapiens (Human)1.0563Known
P42679Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic ...Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyMATK4145;Homo sapiens (Human)1.03727Known
O15111Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyCHUK1147;Homo sapiens (Human)1.01102Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)1.00854Known
P51957Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK46787;Homo sapiens (Human)0.992683Known
Q6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein ...Protein kinase superfamily, Ser/Thr protein kinase familyDSTYK25778;Homo sapiens (Human)0.986288Known
P51817cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKX5613;Homo sapiens (Human)0.979403Known
Q9HC98Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK610783;Homo sapiens (Human)0.965983Known
Q00537Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK175128;Homo sapiens (Human)0.964763Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)0.960942Known
O15146Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase familyMUSK4593;Homo sapiens (Human)0.959127Known
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)0.926821Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)0.923705Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)0.905505Known
Q96BR1Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK3100533105;23678;Homo sapiens (Human)0.878948Known
P54756Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA52044;Homo sapiens (Human)0.876885Known
Q13233Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K14214;Homo sapiens (Human)0.871196Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)0.866251Known
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)0.859835Known
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)0.855189Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)0.844441Known
Q8TD19Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK991754;Homo sapiens (Human)0.835471Known
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)0.829907Known
Q92630Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK28445;Homo sapiens (Human)0.823851Known
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)0.821052Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)0.820469Known
Q9UEW8STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK3927347;Homo sapiens (Human)0.810207Known
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)0.8Known
P49761Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK31198;Homo sapiens (Human)0.795959Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)0.795002Known
O14578Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)Protein kinase superfamily, AGC Ser/Thr protein kinase familyCIT11113;Homo sapiens (Human)0.788899Known
Q8NEV4Myosin-IIIa (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3A53904;Homo sapiens (Human)0.764992Known
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)0.75557Known
Q9Y6E0Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK248428;Homo sapiens (Human)0.754109Known
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)0.749935Known
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)0.710259Known
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)0.705611Known
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)0.677611Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)0.665292Known
Q9UBE8Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...NLK51701;Homo sapiens (Human)0.66409Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)0.656335Known
O75914Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK35063;Homo sapiens (Human)0.648973Known
Q9H4B4Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK31263;Homo sapiens (Human)0.631865Known
Q9HCP0Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G153944;Homo sapiens (Human)0.625Known
P37173TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR27048;Homo sapiens (Human)0.620324Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)0.601386Known
Q96PY6Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK14750;Homo sapiens (Human)0.584491Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)0.583469Known
P45985Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K46416;Homo sapiens (Human)0.57423Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)0.56997Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)0.569877Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)0.563198Known
P22694cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACB5567;Homo sapiens (Human)0.498633Known
Q59H18Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase ...TNNI3K100526835;51086;Homo sapiens (Human)0.484645Known
P53671LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK23985;Homo sapiens (Human)0.483127Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)0.479111Known
Q9Y2H1Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySTK38L23012;Homo sapiens (Human)0.427634Known
Q9NRM7Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS226524;Homo sapiens (Human)0.408456Known
Q13705Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2B93;Homo sapiens (Human)0.407696Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)0.394708Known
Q9BUB5MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK18569;Homo sapiens (Human)0.377247Known
Q8WXR4Myosin-IIIb (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3B140469;Homo sapiens (Human)0.362486Known
O95382Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K69064;Homo sapiens (Human)0.351698Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)0.31053Known
O75460Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyERN12081;Homo sapiens (Human)0.305138Known
Q9Y6M4Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G31456;Homo sapiens (Human)0.301425Known

[16] CHEMBL288441

Original SMILES:
COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl

Prepared SMILES:
COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N

P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)3.651541
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)2.96199Known
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)2.73158Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)2.68245Known
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)2.53132Known
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)2.45443Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)2.42829Known
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)2.421092
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)2.37398Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)2.36538Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)2.32454Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)2.31886Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)2.31423
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)2.30487Known
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)2.2778Known
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)2.2284Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)2.21906Known
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)2.217574
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)2.21552Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)2.20939Known
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)2.2075Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)2.20463Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)2.20006Known
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)2.172535
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)2.15852Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)2.151826
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)2.12755Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)2.091767
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)2.07958Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)2.055368
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)2.05508Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)2.03346Known
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)1.997Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)1.99007Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)1.984169
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)1.98396Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.9756Known
P54764Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA42043;Homo sapiens (Human)1.96837Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.9595510
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)1.94238Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)1.93872Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)1.9156511
Q04759Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCQ5588;Homo sapiens (Human)1.9117Known
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)1.91001Known
Q13164Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK75598;Homo sapiens (Human)1.89836Known
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.89663Known
Q136395-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4)G-protein coupled receptor 1 familyHTR43360;Homo sapiens (Human)1.8913112
Q00535Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK51020;Homo sapiens (Human)1.8802813
P0C1S8Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) ...Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE2494551;Homo sapiens (Human)1.87266Known
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.87239Known
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)1.8646914
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.84569Known
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.84192Known
P27448MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK34140;Homo sapiens (Human)1.8384115
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.8360216
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)1.83115Known
Q00526Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK31018;Homo sapiens (Human)1.8257717
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)1.8062218
Q9P289Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2651765;Homo sapiens (Human)1.80045Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)1.78118Known
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)1.764919
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)1.76475Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)1.75535Known
Q15375Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA72045;Homo sapiens (Human)1.7442920
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)1.7288221
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)1.7159Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)1.70981Known
P04049RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyRAF15894;Homo sapiens (Human)1.707922
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)1.70024Known
P29323Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB22048;Homo sapiens (Human)1.69595Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)1.68376Known
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)1.67878Known
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)1.67352Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.66527Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)1.6617723
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)1.65952Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)1.65297Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.6388Known
Q8TD08Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15225689;Homo sapiens (Human)1.6385324
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)1.63644Known
Q9C098Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK385443;Homo sapiens (Human)1.63628Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)1.6302Known
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)1.61367Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.60888Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)1.60663Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)1.60131Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)1.5979525
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)1.5971126
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)1.58969Known
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)1.5805427
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.5747128
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)1.56615Known
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.5529
P14616Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSRR3645;Homo sapiens (Human)1.5476530
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)1.54198Known
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)1.52064Known
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)1.5191Known
P17252Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCA5578;Homo sapiens (Human)1.5129831
P54756Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA52044;Homo sapiens (Human)1.51248Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)1.51058Known
P41279Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (Cancer Osaka ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K81326;Homo sapiens (Human)1.5002632
P05771Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCB5579;Homo sapiens (Human)1.4993433
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.49209Known
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)1.4883434
P54753Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB32049;Homo sapiens (Human)1.48453Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)1.4825Known
Q9NYY3Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK210769;Homo sapiens (Human)1.48169Known
O94921Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK145218;Homo sapiens (Human)1.47544Known
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)1.4740135
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.4546936
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)1.44246Known
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)1.43877Known
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)1.42823Known
Q00537Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK175128;Homo sapiens (Human)1.4270837
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)1.41981Known
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)1.41637Known
P20794Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyMAK4117;Homo sapiens (Human)1.4103538
Q96D53Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase ...Protein kinase superfamily, ADCK protein kinase familyCOQ8B79934;Homo sapiens (Human)1.4026839
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)1.397940
Q15759Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK115600;Homo sapiens (Human)1.3963941
Q9UIK4Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK223604;Homo sapiens (Human)1.3962542
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)1.38624Known
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)1.37236Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.37211Known
Q96L34MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK457787;Homo sapiens (Human)1.3687543
P24723Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCH5583;Homo sapiens (Human)1.3574644
Q13557Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2D817;Homo sapiens (Human)1.3557445
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.35563Known
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)1.35419Known
Q9BWU1Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1923097;Homo sapiens (Human)1.3438346
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)1.34336Known
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)1.3431647
O15146Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase familyMUSK4593;Homo sapiens (Human)1.3423248
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)1.339149
Q9Y6R4Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K44216;Homo sapiens (Human)1.33756Known
O14920Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKB3551;Homo sapiens (Human)1.3334650
Q16816Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG15260;Homo sapiens (Human)1.31822Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)1.30519Known
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.29918Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)1.29593Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)1.29113Known
Q6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein ...Protein kinase superfamily, Ser/Thr protein kinase familyDSTYK25778;Homo sapiens (Human)1.28765Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)1.28755Known
Q13555Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2G818;Homo sapiens (Human)1.27782Known
Q59H18Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase ...TNNI3K100526835;51086;Homo sapiens (Human)1.27483Known
Q9Y6E0Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK248428;Homo sapiens (Human)1.27089Known
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.2681Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.26436Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)1.25926Known
P42680Tyrosine-protein kinase Tec (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTEC7006;Homo sapiens (Human)1.24252Known
P41240Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyCSK1445;Homo sapiens (Human)1.23896Known
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.22301Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)1.21983Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)1.20525Known
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)1.20176Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)1.18226Known
P53350Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK15347;Homo sapiens (Human)1.18139Known
Q05655Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCD5580;Homo sapiens (Human)1.16271Known
Q9Y2K2Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK323387;Homo sapiens (Human)1.16093Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)1.1595Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)1.15838Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)1.15558Known
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)1.15376Known
Q9BXA7Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK1B83942;Homo sapiens (Human)1.13446Known
O14936Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; ...CASK8573;Homo sapiens (Human)1.13085Known
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.12571Known
P49674Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1E102800317;1454;Homo sapiens (Human)1.12147Known
P43403Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) ...Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilyZAP707535;Homo sapiens (Human)1.12046Known
P49761Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK31198;Homo sapiens (Human)1.11177Known
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)1.1019Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)1.0967Known
O75914Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK35063;Homo sapiens (Human)1.08252Known
O00506Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2510494;Homo sapiens (Human)1.08105Known
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)1.07072Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)1.07037Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)1.07024Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)1.06791Known
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)1.06704Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)1.06563Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)1.03528Known
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)1.0207Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)1.01966Known
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)1.01903Known
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)1.01666Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)1.01017Known
Q96Q40Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1565061;Homo sapiens (Human)1.0085Known
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2A815;Homo sapiens (Human)0.988931Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)0.979464Known
P48729Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A11452;Homo sapiens (Human)0.979227Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)0.97429Known
P51955Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK24751;Homo sapiens (Human)0.973556Known
Q8WTQ7Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK7131890;Homo sapiens (Human)0.967215Known
Q8WU08Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySTK32A202374;Homo sapiens (Human)0.960685Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)0.952627Known
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)0.948712Known
Q9Y2H9Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)Protein kinase superfamily, AGC Ser/Thr protein kinase familyMAST122983;Homo sapiens (Human)0.946678Known
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)0.92244Known
Q99640Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyPKMYT19088;Homo sapiens (Human)0.921408Known
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)0.91262Known
O14730Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK38780;Homo sapiens (Human)0.91233Known
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)0.906148Known
Q09013Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyDMPK1760;Homo sapiens (Human)0.900698Known
Q9UBE8Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...NLK51701;Homo sapiens (Human)0.899195Known
Q9UKI8Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyTLK19874;Homo sapiens (Human)0.892764Known
Q9NRP7Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)Protein kinase superfamily, Ser/Thr protein kinase familySTK3627148;Homo sapiens (Human)0.877177Known
P45985Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K46416;Homo sapiens (Human)0.863565Known
Q8WXR4Myosin-IIIb (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3B140469;Homo sapiens (Human)0.859716Known
Q8NG66Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK1179858;Homo sapiens (Human)0.854458Known
Q9BRS2Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK183732;Homo sapiens (Human)0.847719Known
Q9UEW8STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK3927347;Homo sapiens (Human)0.824101Known
O14733Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K75609;Homo sapiens (Human)0.822809Known
Q13177Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK25062;Homo sapiens (Human)0.820509Known
Q99755Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC ...PIP5K1A8394;Homo sapiens (Human)0.817625Known
Q13153Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK15058;Homo sapiens (Human)0.806173Known
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)0.805865Known
Q16512Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN15585;Homo sapiens (Human)0.802364Known
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)0.801438Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)0.796794Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)0.791793Known
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)0.788729Known
Q9BQI3Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK127102;Homo sapiens (Human)0.7439Known
Q86Y07Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, VRK subfamilyVRK27444;Homo sapiens (Human)0.74243Known
P30291Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE17465;Homo sapiens (Human)0.735538Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)0.732115Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)0.721936Known
P48730Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein ...Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1D1453;Homo sapiens (Human)0.720235Known
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)0.711399Known
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)0.703784Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)0.699252Known
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)0.667991Known
Q8IY84Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyNIM1K167359;Homo sapiens (Human)0.667475Known
P52564Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K65608;Homo sapiens (Human)0.657849Known
Q02156Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCE5581;Homo sapiens (Human)0.649175Known
Q8NEV4Myosin-IIIa (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3A53904;Homo sapiens (Human)0.628516Known
Q13873Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR2659;Homo sapiens (Human)0.601408Known
Q86UE8Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase ...Protein kinase superfamily, Ser/Thr protein kinase familyTLK211011;Homo sapiens (Human)0.563085Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)0.560579Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)0.495492Known
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)0.478278Known
Q8NFD2Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyANKK1255239;Homo sapiens (Human)0.473774Known
Q13233Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K14214;Homo sapiens (Human)0.469052Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)0.464326Known
P42679Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic ...Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyMATK4145;Homo sapiens (Human)0.428052Known
O14578Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)Protein kinase superfamily, AGC Ser/Thr protein kinase familyCIT11113;Homo sapiens (Human)0.41522Known
Q8N752Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A1L122011;Homo sapiens (Human)0.386598Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)0.312623Known
P57058Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyHUNK30811;Homo sapiens (Human)0.287418Known

[18] CHEMBL1721885

Original SMILES:
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1

Prepared SMILES:
O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2

P48067Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier ...Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A9 subfamilySLC6A96536;Homo sapiens (Human)3.324671
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)3.319862
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)3.299633
P35462D(3) dopamine receptor (Dopamine D3 receptor)G-protein coupled receptor 1 familyDRD31814;Homo sapiens (Human)3.262754
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)3.01965
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)2.49386
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)2.448347
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)2.409038
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)2.307799
P09874Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like ...PARP1142;Homo sapiens (Human)2.2505210
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)2.1546711
P35270Sepiapterin reductase (SPR) (EC 1.1.1.153)Sepiapterin reductase familySPR6697;Homo sapiens (Human)2.1479712
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.0505513
P49286Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)G-protein coupled receptor 1 familyMTNR1B4544;Homo sapiens (Human)1.9578114
O14744Protein arginine N-methyltransferase 5 (EC 2.1.1.320) (72 kDa ICln-binding protein) ...Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase familyPRMT510419;Homo sapiens (Human)1.8570215
P21917D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)G-protein coupled receptor 1 familyDRD41815;Homo sapiens (Human)1.819316
P03372Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 ...Nuclear hormone receptor family, NR3 subfamilyESR12099;Homo sapiens (Human)1.7439417
P48039Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)G-protein coupled receptor 1 familyMTNR1A4543;Homo sapiens (Human)1.7285718
P089085-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamilyHTR1A3350;Homo sapiens (Human)1.7033819
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)1.700720
Q9HCG7Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (Beta-glucocerebrosidase 2) (Beta-glucosidase 2) (Bile ...Non-lysosomal glucosylceramidase familyGBA257704;Homo sapiens (Human)1.6897221
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.6734722
O43570Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA12771;Homo sapiens (Human)1.6489523
P35367Histamine H1 receptor (H1R) (HH1R)G-protein coupled receptor 1 familyHRH13269;Homo sapiens (Human)1.6312324
Q136395-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4)G-protein coupled receptor 1 familyHTR43360;Homo sapiens (Human)1.5707625
P00918Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA2760;Homo sapiens (Human)1.5601926
P78527DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC ...PI3/PI4-kinase familyPRKDC5591;Homo sapiens (Human)1.5587727
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)1.5219128
Q13547Histone deacetylase 1 (HD1) (EC 3.5.1.98)Histone deacetylase family, HD type 1 subfamilyHDAC13065;Homo sapiens (Human)1.5137329
P34913Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) ...AB hydrolase superfamily, Epoxide hydrolase familyEPHX22053;Homo sapiens (Human)1.5038930
P09960Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)Peptidase M1 familyLTA4H4048;Homo sapiens (Human)1.4756431
P415955-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)G-protein coupled receptor 1 familyHTR2B3357;Homo sapiens (Human)1.474932
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)1.4466333
Q99720Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding ...ERG2 familySIGMAR110280;Homo sapiens (Human)1.4360234
Q92731Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A ...Nuclear hormone receptor family, NR3 subfamilyESR22100;Homo sapiens (Human)1.3735135
Q99705Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein ...G-protein coupled receptor 1 familyMCHR12847;Homo sapiens (Human)1.3559936
P349695-hydroxytryptamine receptor 7 (5-HT-7) (5-HT7) (5-HT-X) (Serotonin receptor 7)G-protein coupled receptor 1 familyHTR73363;Homo sapiens (Human)1.353337
O15379Histone deacetylase 3 (HD3) (EC 3.5.1.98) (RPD3-2) (SMAP45)Histone deacetylase family, HD type 1 subfamilyHDAC38841;Homo sapiens (Human)1.3532738
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)1.3526139
P31645Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family ...Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamilySLC6A46532;Homo sapiens (Human)1.3495440
P00915Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA1759;Homo sapiens (Human)1.3173441
P35348Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) ...G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1A sub-subfamilyADRA1A148;Homo sapiens (Human)1.3154842
Q8NER1Transient receptor potential cation channel subfamily V member 1 (TrpV1) ...Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamilyTRPV17442;Homo sapiens (Human)1.3031843
P00742Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved ...Peptidase S1 familyF102159;Homo sapiens (Human)1.2795644
P41146Nociceptin receptor (Kappa-type 3 opioid receptor) (KOR-3) (Orphanin FQ receptor)G-protein coupled receptor 1 familyOPRL14987;Homo sapiens (Human)1.2643145
P504065-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)G-protein coupled receptor 1 familyHTR63362;Homo sapiens (Human)1.2470646
Q16790Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA9768;Homo sapiens (Human)1.241147
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)1.2308448
P11511Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen ...Cytochrome P450 familyCYP19A11588;Homo sapiens (Human)1.2264649
P27338Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) ...Flavin monoamine oxidase familyMAOB4129;Homo sapiens (Human)1.2131150

[19] CHEMBL1287853

Original SMILES:
Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1

Prepared SMILES:
Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1

P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)3.24354Known
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)3.16341Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)3.14845Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)3.02944Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)2.97173Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)2.91122Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)2.88619Known
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)2.86287Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)2.79437Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)2.76616Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)2.75587Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)2.71679Known
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)2.663221
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)2.63216Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)2.57806Known
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)2.56824Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)2.55166Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)2.54748Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)2.52476Known
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)2.523632
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)2.52205Known
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)2.50597Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)2.49694Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)2.4737Known
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)2.45283Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)2.40505Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)2.40245Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)2.34405Known
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)2.33537Known
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)2.32413Known
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)2.30172Known
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)2.29921Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)2.29476Known
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)2.29451Known
P30291Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE17465;Homo sapiens (Human)2.27457Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)2.26365Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.2195Known
P42680Tyrosine-protein kinase Tec (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTEC7006;Homo sapiens (Human)2.206863
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)2.18074Known
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)2.145824
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)2.14197Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)2.06648Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)2.0514Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)2.04113Known
Q9NYY3Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK210769;Homo sapiens (Human)2.02516Known
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)2.00472Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)2.000025
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.999486
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)1.99321Known
P27448MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK34140;Homo sapiens (Human)1.98071Known
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)1.97835Known
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)1.97475Known
P48736Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) ...PI3/PI4-kinase familyPIK3CG5294;Homo sapiens (Human)1.96216Known
Q00526Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK31018;Homo sapiens (Human)1.961317
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.953378
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.92388Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)1.92229Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)1.90938Known
Q96L34MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK457787;Homo sapiens (Human)1.90851Known
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)1.89509Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.88604Known
Q9C098Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK385443;Homo sapiens (Human)1.87485Known
Q00535Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK51020;Homo sapiens (Human)1.869319
P14616Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSRR3645;Homo sapiens (Human)1.85156Known
Q96D53Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase ...Protein kinase superfamily, ADCK protein kinase familyCOQ8B79934;Homo sapiens (Human)1.84035Known
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)1.83044Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)1.83019Known
P17252Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCA5578;Homo sapiens (Human)1.8215910
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)1.81195Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)1.80832Known
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)1.80688Known
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)1.80393Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)1.79217Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)1.78849Known
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)1.7841711
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)1.77928Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)1.7750212
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.77513
P34913Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) ...AB hydrolase superfamily, Epoxide hydrolase familyEPHX22053;Homo sapiens (Human)1.770414
Q9NWT8Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, ...Mitochondrion-specific ribosomal protein mS38 familyAURKAIP154998;Homo sapiens (Human)1.7672615
Q52WX2Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySBK1388228;Homo sapiens (Human)1.76587Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)1.7553Known
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)1.75312Known
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)1.7499916
P37023Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVRL194;Homo sapiens (Human)1.74979Known
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)1.74462Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)1.74405Known
O14920Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKB3551;Homo sapiens (Human)1.74282Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)1.74074Known
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.73346Known
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)1.73005Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)1.72996Known
O94921Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK145218;Homo sapiens (Human)1.72654Known
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.72191Known
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)1.7085317
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)1.70609Known
Q9BXA7Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK1B83942;Homo sapiens (Human)1.70609Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)1.70229Known
P42336Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) ...PI3/PI4-kinase familyPIK3CA5290;Homo sapiens (Human)1.70122Known
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)1.69916Known
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)1.698118
Q13164Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK75598;Homo sapiens (Human)1.69614Known
Q13557Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2D817;Homo sapiens (Human)1.68724Known
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)1.66992Known
Q16816Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG15260;Homo sapiens (Human)1.66954Known
O75914Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK35063;Homo sapiens (Human)1.6651819
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)1.6520
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.6521
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.6465222
Q8N568Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK2166614;Homo sapiens (Human)1.64549Known
P78362SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK26733;Homo sapiens (Human)1.64245Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)1.63558Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.62869Known
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)1.614Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)1.59677Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.59651Known
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)1.58769Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.58699Known
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)1.5843323
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)1.57524
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.57471Known
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.57439Known
Q9P286Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK557144;Homo sapiens (Human)1.5677Known
Q8TD19Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK991754;Homo sapiens (Human)1.56385Known
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)1.5606725
Q15759Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK115600;Homo sapiens (Human)1.5559526
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)1.55495Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)1.55443Known
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.54853Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)1.54794Known
Q13555Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2G818;Homo sapiens (Human)1.5471Known
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.54576Known
P0C1S8Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) ...Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE2494551;Homo sapiens (Human)1.53122Known
Q05655Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCD5580;Homo sapiens (Human)1.52527
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)1.5249928
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)1.5249Known
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.52476Known
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)1.52065Known
O43570Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA12771;Homo sapiens (Human)1.5085729
P53355Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK11612;Homo sapiens (Human)1.50396Known
Q8TDC3Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK184446;Homo sapiens (Human)1.530
P42338Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) ...PI3/PI4-kinase familyPIK3CB5291;Homo sapiens (Human)1.4987931
O00329Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) ...PI3/PI4-kinase familyPIK3CD5293;Homo sapiens (Human)1.4941532
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.49352Known
Q15375Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA72045;Homo sapiens (Human)1.48814Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.48305Known
P00918Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA2760;Homo sapiens (Human)1.4813533
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)1.4769634
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.46945Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)1.46887Known
P36894Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1A657;Homo sapiens (Human)1.456835
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)1.45553Known
Q9BWU1Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1923097;Homo sapiens (Human)1.4543736
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.45312Known
Q00534Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK61021;Homo sapiens (Human)1.4530237
Q9Y2K2Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK323387;Homo sapiens (Human)1.44498Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)1.44471Known
P53350Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK15347;Homo sapiens (Human)1.44005Known
Q8TD08Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15225689;Homo sapiens (Human)1.43317Known
P24723Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCH5583;Homo sapiens (Human)1.4317138
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)1.43097Known
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)1.42465Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)1.42288Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)1.42082Known
P09960Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)Peptidase M1 familyLTA4H4048;Homo sapiens (Human)1.4206839
O15146Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase familyMUSK4593;Homo sapiens (Human)1.42049Known
O94768Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17B9262;Homo sapiens (Human)1.4171Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)1.41664Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)1.41367Known
Q13705Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2B93;Homo sapiens (Human)1.4053540
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)1.40493Known
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)1.4014Known
Q9UIK4Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK223604;Homo sapiens (Human)1.39705Known
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.39625Known
O15111Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyCHUK1147;Homo sapiens (Human)1.39442Known
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)1.39129Known
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)1.388441
Q07002Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK185129;Homo sapiens (Human)1.38686Known
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)1.38503Known
Q9P0L2Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK14139;Homo sapiens (Human)1.38299Known
Q16790Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA9768;Homo sapiens (Human)1.3765742
P0C264Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family ...Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamilySBK3100130827;Homo sapiens (Human)1.37127Known
Q8TDX7Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK7140609;Homo sapiens (Human)1.36147Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)1.35959Known
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)1.35672Known
Q9H4B4Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK31263;Homo sapiens (Human)1.34846Known
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)1.34471Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)1.34144Known
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)1.33632Known
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.32839Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)1.32217Known
Q59H18Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase ...TNNI3K100526835;51086;Homo sapiens (Human)1.32006Known
Q86YV6Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4340156;Homo sapiens (Human)1.31835Known
Q7KZI7Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK22011;Homo sapiens (Human)1.3163Known
Q13237cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG25593;Homo sapiens (Human)1.31484Known
Q15139Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD15587;Homo sapiens (Human)1.308743
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.30809Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)1.30637Known
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.30357Known
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)1.29798Known
Q15831Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamilySTK116794;Homo sapiens (Human)1.29654Known
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)1.29578Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.29444Known
Q8IVW4Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine-protein kinase NKIAMRE)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL351265;Homo sapiens (Human)1.2934844
P36896Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR1B91;Homo sapiens (Human)1.29087Known
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.28063Known
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)1.27014Known
P37173TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR27048;Homo sapiens (Human)1.26773Known
P20794Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyMAK4117;Homo sapiens (Human)1.2631745
Q15569Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyTESK17016;Homo sapiens (Human)1.2556Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.25233Known
P04049RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyRAF15894;Homo sapiens (Human)1.2491546
Q9HC98Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK610783;Homo sapiens (Human)1.23999Known
P78356Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2B8396;Homo sapiens (Human)1.23111Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)1.22118Known
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.21994Known
O14936Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; ...CASK8573;Homo sapiens (Human)1.21261Known
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)1.20989Known
P27986Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K ...PI3K p85 subunit familyPIK3R15295;Homo sapiens (Human)1.2070447
P03372Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 ...Nuclear hormone receptor family, NR3 subfamilyESR12099;Homo sapiens (Human)1.1981448
P19525Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK25610;Homo sapiens (Human)1.18489Known
Q9P289Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2651765;Homo sapiens (Human)1.18148Known
P546465'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA25563;Homo sapiens (Human)1.17087Known
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)1.17052Known
Q96Q40Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1565061;Homo sapiens (Human)1.17046Known
P349695-hydroxytryptamine receptor 7 (5-HT-7) (5-HT7) (5-HT-X) (Serotonin receptor 7)G-protein coupled receptor 1 familyHTR73363;Homo sapiens (Human)1.1699249
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.16344Known
P51957Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK46787;Homo sapiens (Human)1.16231Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)1.1533750
Q6P3R8Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK5341676;Homo sapiens (Human)1.15299Known
P29323Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB22048;Homo sapiens (Human)1.14735Known
P45985Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K46416;Homo sapiens (Human)1.14205Known
O15075Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK19201;Homo sapiens (Human)1.1376Known
Q8TBX8Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2C79837;Homo sapiens (Human)1.13423Known
O14730Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK38780;Homo sapiens (Human)1.1328Known
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)1.1266Known
Q96SB4SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK16732;Homo sapiens (Human)1.12397Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)1.11838Known
Q9UKI8Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyTLK19874;Homo sapiens (Human)1.09965Known
Q8WTQ7Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK7131890;Homo sapiens (Human)1.09173Known
Q02779Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K104294;Homo sapiens (Human)1.07994Known
Q13873Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR2659;Homo sapiens (Human)1.07847Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)1.07621Known
Q96BR1Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK3100533105;23678;Homo sapiens (Human)1.06996Known
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)1.057Known
Q9BRS2Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK183732;Homo sapiens (Human)1.05045Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)1.04713Known
Q16512Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN15585;Homo sapiens (Human)1.0363Known
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)1.02893Known
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2A815;Homo sapiens (Human)1.02723Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)1.02716Known
Q00537Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK175128;Homo sapiens (Human)1.01663Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)1.01638Known
Q13177Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK25062;Homo sapiens (Human)1.00733Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)1.00365Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)0.999745Known
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)0.992493Known
Q9UBF8Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) ...PI3/PI4-kinase family, Type III PI4K subfamilyPI4KB5298;Homo sapiens (Human)0.981678Known
Q13976cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG15592;Homo sapiens (Human)0.980054Known
O60885Bromodomain-containing protein 4 (Protein HUNK1)BRD423476;Homo sapiens (Human)0.968412Known
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)0.966785Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)0.962663Known
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)0.955289Known
Q14012Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK18536;Homo sapiens (Human)0.950981Known
Q9NRP7Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)Protein kinase superfamily, Ser/Thr protein kinase familySTK3627148;Homo sapiens (Human)0.949187Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)0.946504Known
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)0.944299Known
Q8NG66Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK1179858;Homo sapiens (Human)0.931832Known
O75460Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyERN12081;Homo sapiens (Human)0.92831Known
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)0.927237Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)0.92424Known
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)0.923675Known
P54764Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA42043;Homo sapiens (Human)0.917936Known
P42679Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic ...Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyMATK4145;Homo sapiens (Human)0.917721Known
Q6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein ...Protein kinase superfamily, Ser/Thr protein kinase familyDSTYK25778;Homo sapiens (Human)0.893508Known
Q9UEW8STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK3927347;Homo sapiens (Human)0.886875Known
P41240Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyCSK1445;Homo sapiens (Human)0.884826Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)0.884247Known
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)0.880054Known
O14578Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)Protein kinase superfamily, AGC Ser/Thr protein kinase familyCIT11113;Homo sapiens (Human)0.875764Known
Q9NRH2SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familySNRK54861;Homo sapiens (Human)0.872794Known
Q58F21Bromodomain testis-specific protein (Cancer/testis antigen 9) (CT9) (RING3-like protein)BRDT676;Homo sapiens (Human)0.871806Known
P51956Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (HSPK 36) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK34752;Homo sapiens (Human)0.869616Known
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)0.865642Known
Q99755Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC ...PIP5K1A8394;Homo sapiens (Human)0.849105Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)0.848537Known
P53671LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK23985;Homo sapiens (Human)0.830948Known
Q9Y463Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1B9149;Homo sapiens (Human)0.830569Known
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)0.821773Known
Q9BQI3Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK127102;Homo sapiens (Human)0.810549Known
Q8IY84Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyNIM1K167359;Homo sapiens (Human)0.808886Known
Q9BUB5MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK18569;Homo sapiens (Human)0.804479Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)0.80341Known
O00506Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2510494;Homo sapiens (Human)0.803302Known
P51955Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK24751;Homo sapiens (Human)0.79213Known
Q9UEE5Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17A9263;Homo sapiens (Human)0.778667Known
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)0.777282Known
Q9H1R3Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK285366;Homo sapiens (Human)0.753356Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)0.743531Known
Q9BVS4Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK255781;Homo sapiens (Human)0.741797Known
P43403Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) ...Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilyZAP707535;Homo sapiens (Human)0.735069Known
Q9Y6R4Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K44216;Homo sapiens (Human)0.706455Known
Q13523Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familyPRPF4B8899;Homo sapiens (Human)0.683061Known
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)0.67383Known
Q86UE8Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase ...Protein kinase superfamily, Ser/Thr protein kinase familyTLK211011;Homo sapiens (Human)0.673306Known
Q92772Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL28999;Homo sapiens (Human)0.643407Known
Q8NFD2Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyANKK1255239;Homo sapiens (Human)0.638169Known
Q96NX5Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1G57172;Homo sapiens (Human)0.635514Known
Q13153Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK15058;Homo sapiens (Human)0.627159Known
Q16659Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK65597;Homo sapiens (Human)0.623191Known
P57078Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK4Homo sapiens (Human)0.617752Known
Q8NI60Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 ...Protein kinase superfamily, ADCK protein kinase familyCOQ8A56997;Homo sapiens (Human)0.610042Known
Q96PY6Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK14750;Homo sapiens (Human)0.596074Known
Q09013Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyDMPK1760;Homo sapiens (Human)0.592571Known
Q9NQU5Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK6106821730;56924;Homo sapiens (Human)0.562665Known
Q15208Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySTK3811329;Homo sapiens (Human)0.527028Known
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)0.51251Known
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)0.489857Known
Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK18737;Homo sapiens (Human)0.466823Known
Q13554Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2B816;Homo sapiens (Human)0.46106Known
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)0.459597Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)0.434688Known
Q02156Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCE5581;Homo sapiens (Human)0.425676Known
O76039Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL56792;Homo sapiens (Human)0.414024Known
Q9NRM7Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS226524;Homo sapiens (Human)0.345227Known

[20] CHEMBL608533

Original SMILES:
CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4

Prepared SMILES:
CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C

P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)3.5165Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)3.43844Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)3.38344Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)3.37304Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)3.32Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)3.26216Known
Q7KZI7Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK22011;Homo sapiens (Human)3.25782Known
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)3.18643Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)3.16842Known
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)3.10935Known
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)3.089971
Q16816Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG15260;Homo sapiens (Human)3.06709Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)3.01427Known
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)2.96332Known
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)2.94966Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)2.92658Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)2.90872Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)2.90192Known
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)2.89594Known
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2A815;Homo sapiens (Human)2.87371Known
Q9UEE5Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17A9263;Homo sapiens (Human)2.86836Known
Q16512Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN15585;Homo sapiens (Human)2.85747Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.85146Known
Q13557Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2D817;Homo sapiens (Human)2.85145Known
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)2.80656Known
P27448MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK34140;Homo sapiens (Human)2.80263Known
Q8WTQ7Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK7131890;Homo sapiens (Human)2.75889Known
P05771Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCB5579;Homo sapiens (Human)2.74882
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)2.71002Known
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)2.69143Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)2.68047Known
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)2.66018Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)2.65618Known
O94768Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17B9262;Homo sapiens (Human)2.64477Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)2.64039Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)2.63679Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)2.61286Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)2.60884Known
Q9P0L2Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK14139;Homo sapiens (Human)2.57926Known
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)2.57773Known
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)2.57353
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)2.55245Known
Q13627Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1A1859;Homo sapiens (Human)2.52423Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)2.52098Known
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)2.51838Known
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)2.50937Known
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)2.50386Known
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)2.48777Known
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)2.48529Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)2.47622Known
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)2.472444
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)2.46864Known
Q15835Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK16011;Homo sapiens (Human)2.45013Known
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)2.44654Known
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)2.44181Known
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)2.434085
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)2.42646Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)2.42542Known
Q9BRS2Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK183732;Homo sapiens (Human)2.42014Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)2.4163Known
Q15139Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD15587;Homo sapiens (Human)2.413176
Q9NRM7Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS226524;Homo sapiens (Human)2.40524Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)2.392987
Q96SB4SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK16732;Homo sapiens (Human)2.3893Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)2.38662Known
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)2.36302Known
Q02156Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCE5581;Homo sapiens (Human)2.36032Known
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)2.35666Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)2.35522Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)2.353748
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)2.34579Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)2.335089
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)2.33158Known
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)2.32238Known
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)2.32213Known
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)2.31428Known
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)2.3087Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)2.3034Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)2.30224Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)2.29497Known
O75914Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK35063;Homo sapiens (Human)2.29376Known
Q99755Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC ...PIP5K1A8394;Homo sapiens (Human)2.27782Known
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)2.27761Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)2.26894Known
Q02779Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K104294;Homo sapiens (Human)2.26427Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)2.25314Known
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)2.25263Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)2.25054Known
P45985Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K46416;Homo sapiens (Human)2.24899Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)2.24876Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)2.24733Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)2.24452Known
P78356Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2B8396;Homo sapiens (Human)2.23844Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)2.23744Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)2.22869Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)2.2267Known
Q9NQU5Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK6106821730;56924;Homo sapiens (Human)2.2196310
Q8IWQ3Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK29024;Homo sapiens (Human)2.21493Known
Q9Y2K2Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK323387;Homo sapiens (Human)2.2008Known
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)2.19929Known
Q9P286Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK557144;Homo sapiens (Human)2.198911
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)2.1981112
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)2.19638Known
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)2.19487Known
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)2.19129Known
P24723Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCH5583;Homo sapiens (Human)2.18328Known
P53355Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK11612;Homo sapiens (Human)2.18059Known
Q04759Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCQ5588;Homo sapiens (Human)2.17721Known
Q05655Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCD5580;Homo sapiens (Human)2.16692Known
P11309Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM15292;Homo sapiens (Human)2.16639Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)2.1607Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)2.15883Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)2.15852Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)2.14791Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)2.14374Known
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)2.13659Known
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)2.1351Known
Q13153Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK15058;Homo sapiens (Human)2.13093Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)2.13077Known
Q13555Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2G818;Homo sapiens (Human)2.11357Known
O15111Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyCHUK1147;Homo sapiens (Human)2.11182Known
Q96L34MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK457787;Homo sapiens (Human)2.10984Known
Q96BR1Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK3100533105;23678;Homo sapiens (Human)2.10321Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)2.10221Known
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)2.10174Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)2.09112Known
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)2.08995Known
P05129Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCG5582;Homo sapiens (Human)2.0890713
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)2.0878Known
Q13554Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2B816;Homo sapiens (Human)2.07785Known
O14730Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK38780;Homo sapiens (Human)2.07414Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)2.07413Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)2.07302Known
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)2.07039Known
P546465'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA25563;Homo sapiens (Human)2.05884Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)2.0423214
Q9Y463Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1B9149;Homo sapiens (Human)2.0247Known
Q13237cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG25593;Homo sapiens (Human)2.00934Known
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)2.0009Known
Q9UIK4Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK223604;Homo sapiens (Human)1.99892Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)1.9923Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.98348Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)1.97888Known
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)1.9606815
Q8TDC3Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK184446;Homo sapiens (Human)1.95729Known
Q86YV6Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4340156;Homo sapiens (Human)1.95722Known
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)1.95597Known
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)1.95538Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)1.94284Known
P43403Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) ...Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilyZAP707535;Homo sapiens (Human)1.94108Known
Q6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein ...Protein kinase superfamily, Ser/Thr protein kinase familyDSTYK25778;Homo sapiens (Human)1.93567Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)1.93558Known
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)1.92775Known
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.9274316
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.92658Known
P51817cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKX5613;Homo sapiens (Human)1.92534Known
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)1.91917
Q92630Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK28445;Homo sapiens (Human)1.9171418
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)1.91523Known
Q13177Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK25062;Homo sapiens (Human)1.91435Known
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)1.9102419
P17252Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCA5578;Homo sapiens (Human)1.90972Known
Q9C098Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK385443;Homo sapiens (Human)1.9048420
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)1.9043521
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.8910522
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)1.88641Known
Q14012Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK18536;Homo sapiens (Human)1.87117Known
P78362SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK26733;Homo sapiens (Human)1.85161Known
Q09013Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyDMPK1760;Homo sapiens (Human)1.84553Known
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)1.8238523
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)1.80551Known
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)1.7982924
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)1.7973Known
P80370Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen ...DLK18788;Homo sapiens (Human)1.7934325
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)1.7887726
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)1.7737527
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)1.76623Known
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)1.76344Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)1.7616928
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)1.75885Known
O75460Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyERN12081;Homo sapiens (Human)1.75403Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.75366Known
Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK18737;Homo sapiens (Human)1.7456329
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)1.7329530
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)1.7245231
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)1.72343Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.7228832
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)1.7176Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)1.70017Known
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)1.69854Known
O95835Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS19113;Homo sapiens (Human)1.69229Known
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.68283Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.68009Known
P57078Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK4Homo sapiens (Human)1.6748333
P22694cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACB5567;Homo sapiens (Human)1.6727Known
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.66072Known
Q13976cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG15592;Homo sapiens (Human)1.65769Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)1.6503634
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.64735Known
Q9BXA7Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK1B83942;Homo sapiens (Human)1.6464Known
P31749RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT1207;Homo sapiens (Human)1.64556Known
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.62663Known
Q5VT25Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPA8476;Homo sapiens (Human)1.6219935
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)1.6197Known
Q9NYY3Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK210769;Homo sapiens (Human)1.6155736
O00506Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2510494;Homo sapiens (Human)1.61002Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)1.59113Known
O00750Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 ...PI3/PI4-kinase familyPIK3C2B5287;Homo sapiens (Human)1.57969Known
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.5704637
Q96NX5Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1G57172;Homo sapiens (Human)1.55185Known
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.5517138
Q52WX2Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySBK1388228;Homo sapiens (Human)1.5498639
Q8TD08Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15225689;Homo sapiens (Human)1.5476740
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)1.5454441
Q8NFD2Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyANKK1255239;Homo sapiens (Human)1.5443342
Q15831Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamilySTK116794;Homo sapiens (Human)1.54082Known
Q00535Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK51020;Homo sapiens (Human)1.5356543
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)1.53281Known
O76039Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL56792;Homo sapiens (Human)1.5238844
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)1.52031Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.51643Known
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)1.50458Known
Q9BWU1Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1923097;Homo sapiens (Human)1.50428Known
Q9Y2H9Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)Protein kinase superfamily, AGC Ser/Thr protein kinase familyMAST122983;Homo sapiens (Human)1.50159Known
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)1.4956945
Q13523Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familyPRPF4B8899;Homo sapiens (Human)1.49319Known
P52564Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K65608;Homo sapiens (Human)1.48702Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)1.4848246
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)1.475947
Q9H1R3Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK285366;Homo sapiens (Human)1.4646748
P48730Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein ...Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1D1453;Homo sapiens (Human)1.4645249
Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)1.453Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.4469250
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)1.4128Known
O14920Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKB3551;Homo sapiens (Human)1.41196Known
P30291Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE17465;Homo sapiens (Human)1.39385Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)1.37889Known
P19525Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK25610;Homo sapiens (Human)1.36734Known
P57058Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyHUNK30811;Homo sapiens (Human)1.35219Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)1.34856Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.31378Known
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.25004Known
O43172U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP ...PRPF49128;Homo sapiens (Human)1.24486Known
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.194Known
P41240Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyCSK1445;Homo sapiens (Human)1.19381Known
P31751RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT2208;Homo sapiens (Human)1.17568Known
Q9H2K2Poly [ADP-ribose] polymerase tankyrase-2 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) ...TNKS280351;Homo sapiens (Human)1.12549Known
P42336Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) ...PI3/PI4-kinase familyPIK3CA5290;Homo sapiens (Human)1.04634Known
O75747Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma (PI3K-C2-gamma) (PtdIns-3-kinase C2 ...PI3/PI4-kinase familyPIK3C2G5288;Homo sapiens (Human)1.03262Known
Q9BVS4Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK255781;Homo sapiens (Human)0.974281Known
Q9Y243RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT310000;Homo sapiens (Human)0.958426Known
Q8WU08Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySTK32A202374;Homo sapiens (Human)0.931027Known
P49761Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK31198;Homo sapiens (Human)0.834806Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)0.798916Known

[21] CHEMBL522892

Original SMILES:
CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1

Prepared SMILES:
CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2

P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)3.39795Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)2.950011
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)2.936352
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)2.897Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)2.85178Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)2.71584Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)2.65009Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)2.60792Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)2.60751Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)2.59608Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.54761Known
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)2.49713Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)2.49446Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)2.454683
Q13557Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2D817;Homo sapiens (Human)2.41759Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)2.35002Known
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)2.321084
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)2.301055
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)2.29036Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)2.279116
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)2.276297
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)2.271528
Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)2.26803Known
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)2.250719
P30291Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE17465;Homo sapiens (Human)2.23189Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)2.1925210
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)2.19138Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)2.18402Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)2.17176Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)2.17166Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)2.15002Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)2.12747Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)2.07563Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)2.07037Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)2.06674Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)2.0624311
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)2.05016Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)2.0406Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)1.97473Known
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)1.9571512
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)1.94163Known
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.93698Known
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)1.93644Known
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)1.9298713
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)1.91944Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)1.91489Known
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.87614Known
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)1.87023Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)1.8684414
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)1.8551615
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)1.85001Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)1.85Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)1.8444816
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)1.83957Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)1.8343Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)1.83188Known
Q05655Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCD5580;Homo sapiens (Human)1.8288Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)1.8277617
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)1.8243Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)1.82371Known
Q92772Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL28999;Homo sapiens (Human)1.82129Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)1.81561Known
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)1.80873Known
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.8043918
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)1.8032319
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.8Known
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)1.7998720
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)1.7924721
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)1.79019Known
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.77499Known
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)1.76129Known
Q96L34MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK457787;Homo sapiens (Human)1.7473Known
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.72749Known
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)1.7258Known
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)1.72257Known
P27448MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK34140;Homo sapiens (Human)1.70769Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)1.6999922
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)1.6804923
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)1.67858Known
P0C1S8Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) ...Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE2494551;Homo sapiens (Human)1.6743924
Q13555Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2G818;Homo sapiens (Human)1.67125Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)1.6691325
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)1.6635726
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.65097Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)1.65Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)1.64212Known
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)1.63693Known
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)1.6361827
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.6134828
Q9Y243RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT310000;Homo sapiens (Human)1.6108629
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)1.60001Known
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)1.57635Known
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)1.5648Known
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)1.555830
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.55232Known
Q04759Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCQ5588;Homo sapiens (Human)1.5493931
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)1.53578Known
Q9Y463Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1B9149;Homo sapiens (Human)1.5343532
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.5326133
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)1.52112Known
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)1.50494Known
P14616Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSRR3645;Homo sapiens (Human)1.4956634
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)1.49535Known
Q00535Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK51020;Homo sapiens (Human)1.4815735
P24723Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCH5583;Homo sapiens (Human)1.4680736
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)1.465537
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.46346Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)1.4609138
P05771Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCB5579;Homo sapiens (Human)1.450739
P05129Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCG5582;Homo sapiens (Human)1.4386140
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)1.438441
P21917D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)G-protein coupled receptor 1 familyDRD41815;Homo sapiens (Human)1.4367642
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)1.425Known
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)1.4218443
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)1.4166844
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)1.4165945
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)1.41465Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.41349Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)1.4067446
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.3999947
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.3981848
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.3958449
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.39535Known
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)1.3919250
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)1.38524Known
Q9BVS4Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK255781;Homo sapiens (Human)1.37203Known
Q9BXA7Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK1B83942;Homo sapiens (Human)1.3663Known
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)1.36486Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)1.36393Known
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)1.35736Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.35Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)1.33251Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.32511Known
Q7KZI7Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK22011;Homo sapiens (Human)1.31523Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)1.29711Known
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)1.28297Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)1.25666Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.25598Known
Q52WX2Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySBK1388228;Homo sapiens (Human)1.24844Known
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)1.24681Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)1.225Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.22164Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)1.20107Known
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.20088Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)1.20021Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)1.2Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.2Known
Q8TDC3Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK184446;Homo sapiens (Human)1.2Known
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)1.19828Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)1.18515Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.16887Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)1.15Known
P51957Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK46787;Homo sapiens (Human)1.1Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)1.08795Known
Q15835Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK16011;Homo sapiens (Human)1.0782Known
Q9HBY8Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2)Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK210110;Homo sapiens (Human)1.075Known
P51955Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK24751;Homo sapiens (Human)1.07397Known
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)1.06658Known
Q9Y2H9Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)Protein kinase superfamily, AGC Ser/Thr protein kinase familyMAST122983;Homo sapiens (Human)1.0564Known
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)1.04423Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)1.0421Known
P78362SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK26733;Homo sapiens (Human)1.02744Known
Q8WTQ7Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK7131890;Homo sapiens (Human)1.02702Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)1.00157Known
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)0.998282Known
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)0.975Known
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)0.942061Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)0.939562Known
Q9UEW8STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK3927347;Homo sapiens (Human)0.93876Known
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)0.930318Known
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)0.92609Known
P51817cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKX5613;Homo sapiens (Human)0.912451Known
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)0.875Known
P57058Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyHUNK30811;Homo sapiens (Human)0.874083Known
Q96SB4SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK16732;Homo sapiens (Human)0.871547Known
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)0.862953Known
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)0.856512Known
Q9NYY3Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK210769;Homo sapiens (Human)0.851423Known
Q15208Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySTK3811329;Homo sapiens (Human)0.832823Known
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)0.818042Known
Q9H1R3Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK285366;Homo sapiens (Human)0.816559Known
O15111Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyCHUK1147;Homo sapiens (Human)0.800571Known
Q86YV6Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4340156;Homo sapiens (Human)0.796576Known
P78356Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2B8396;Homo sapiens (Human)0.76558Known
Q07002Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK185129;Homo sapiens (Human)0.734262Known
Q9NRM7Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS226524;Homo sapiens (Human)0.732832Known
P48730Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein ...Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1D1453;Homo sapiens (Human)0.714258Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)0.708582Known
Q16512Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN15585;Homo sapiens (Human)0.676695Known
Q96BR1Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK3100533105;23678;Homo sapiens (Human)0.658367Known
Q13523Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familyPRPF4B8899;Homo sapiens (Human)0.643779Known
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)0.627862Known
Q8IY84Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyNIM1K167359;Homo sapiens (Human)0.626286Known
Q02779Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K104294;Homo sapiens (Human)0.573407Known
Q92630Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK28445;Homo sapiens (Human)0.552605Known
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)0.546197Known
O60331Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC ...PIP5K1C23396;Homo sapiens (Human)0.422027Known
Q8NFD2Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyANKK1255239;Homo sapiens (Human)0.389626Known
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)0.328741Known

[22] CHEMBL601719

Original SMILES:
C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl

Prepared SMILES:
Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1

P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)4.6718Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)3.7516Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)3.458391
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)3.20594Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)3.14711Known
Q15139Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD15587;Homo sapiens (Human)3.09068Known
Q00537Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK175128;Homo sapiens (Human)3.087572
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)3.07719Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)2.91662Known
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)2.89633
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)2.867Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)2.86374Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)2.8367Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)2.81465Known
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)2.80955Known
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)2.76227Known
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)2.723854
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)2.667785
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)2.645496
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)2.62793Known
P366397,8-dihydro-8-oxoguanine triphosphatase (EC 3.6.1.55) (2-hydroxy-dATP diphosphatase) (EC 3.6.1.56) (8-oxo-dGTPase) (Nucleoside ...Nudix hydrolase familyNUDT14521;Homo sapiens (Human)2.595567
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)2.59203Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)2.55114Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)2.540528
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)2.48964Known
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)2.474469
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)2.45317Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)2.44355Known
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)2.4335910
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)2.4273511
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)2.41827Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)2.40494Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)2.4029Known
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)2.3945912
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)2.3718313
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)2.36464Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)2.35027Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)2.33379Known
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)2.32134Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)2.2989914
O76039Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL56792;Homo sapiens (Human)2.2928915
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)2.24352Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)2.23215Known
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)2.2255216
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)2.1993417
O14936Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; ...CASK8573;Homo sapiens (Human)2.17879Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)2.15416Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)2.1231318
Q9UQ88Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK11A728642;Homo sapiens (Human)2.11423Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)2.09898Known
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)2.0967Known
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)2.07834Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)2.07181Known
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)2.0607119
P48730Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein ...Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1D1453;Homo sapiens (Human)2.0483920
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)2.0353221
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)2.0308522
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)2.02291Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)2.0210423
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)2.00696Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)2.00335Known
Q13164Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK75598;Homo sapiens (Human)2.00114Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.00079Known
P21127Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK11B984;Homo sapiens (Human)1.9713Known
P37023Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVRL194;Homo sapiens (Human)1.9657524
P53671LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK23985;Homo sapiens (Human)1.96045Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)1.9575525
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)1.94085Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)1.92152Known
O94921Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK145218;Homo sapiens (Human)1.9173626
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.9126627
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.9025528
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.89307Known
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.88768Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.88138Known
Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK18737;Homo sapiens (Human)1.87595Known
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)1.87352Known
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.86896Known
P51955Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK24751;Homo sapiens (Human)1.8675729
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)1.86598Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)1.8602Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)1.8508930
P54764Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA42043;Homo sapiens (Human)1.84737Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)1.83467Known
Q96Q40Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1565061;Homo sapiens (Human)1.8237531
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)1.8213132
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.8002533
O95497Pantetheinase (EC 3.5.1.92) (Pantetheine hydrolase) (Tiff66) (Vascular non-inflammatory molecule 1) ...Carbon-nitrogen hydrolase superfamily, BTD/VNN familyVNN18876;Homo sapiens (Human)1.7757234
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)1.77084Known
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.76726Known
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)1.75366Known
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.7478535
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)1.746936
P49674Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1E102800317;1454;Homo sapiens (Human)1.7279837
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)1.72527Known
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)1.72474Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)1.69319Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)1.6857538
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.68347Known
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)1.6691439
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)1.6673240
Q07002Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK185129;Homo sapiens (Human)1.653141
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)1.6519942
O15146Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase familyMUSK4593;Homo sapiens (Human)1.63424Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.63363Known
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.61997Known
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)1.6155943
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)1.61249Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)1.61067Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)1.6049Known
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)1.5891744
Q00526Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK31018;Homo sapiens (Human)1.5783245
Q9BWU1Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1923097;Homo sapiens (Human)1.575146
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.57312Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)1.57268Known
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)1.5591347
Q15759Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK115600;Homo sapiens (Human)1.5574948
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)1.557149
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.55154Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.5376Known
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)1.5372250
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)1.49763Known
Q15375Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA72045;Homo sapiens (Human)1.47608Known
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)1.46089Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)1.4477Known
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.44709Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)1.44504Known
Q6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein ...Protein kinase superfamily, Ser/Thr protein kinase familyDSTYK25778;Homo sapiens (Human)1.40808Known
P36896Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR1B91;Homo sapiens (Human)1.40483Known
Q15569Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyTESK17016;Homo sapiens (Human)1.38786Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)1.37896Known
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)1.36738Known
Q52WX2Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySBK1388228;Homo sapiens (Human)1.34635Known
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)1.32621Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)1.31756Known
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)1.31092Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.30718Known
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.30343Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.3005Known
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)1.28268Known
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)1.28115Known
P14616Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSRR3645;Homo sapiens (Human)1.27471Known
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)1.27432Known
Q59H18Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase ...TNNI3K100526835;51086;Homo sapiens (Human)1.27191Known
Q92772Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL28999;Homo sapiens (Human)1.26625Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.25108Known
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)1.24352Known
Q8TD19Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK991754;Homo sapiens (Human)1.23221Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.22004Known
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)1.20425Known
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)1.18349Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)1.14404Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)1.13565Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)1.11185Known
Q6ZN16Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K15389840;Homo sapiens (Human)1.10288Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)1.09539Known
P0C264Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family ...Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamilySBK3100130827;Homo sapiens (Human)1.09452Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)1.08607Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.07784Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)1.02311Known
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)1.02023Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)1.0102Known
Q09013Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyDMPK1760;Homo sapiens (Human)0.996439Known
O15075Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK19201;Homo sapiens (Human)0.993207Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)0.989134Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)0.982275Known
Q8NFD2Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyANKK1255239;Homo sapiens (Human)0.973751Known
P19525Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK25610;Homo sapiens (Human)0.954185Known
Q8N568Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK2166614;Homo sapiens (Human)0.879431Known
P57078Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK4Homo sapiens (Human)0.876998Known
Q9BRS2Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK183732;Homo sapiens (Human)0.873215Known
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)0.865166Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)0.844313Known
Q96D53Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase ...Protein kinase superfamily, ADCK protein kinase familyCOQ8B79934;Homo sapiens (Human)0.832916Known
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)0.826218Known
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)0.813729Known
O14920Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKB3551;Homo sapiens (Human)0.806776Known
P43403Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) ...Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilyZAP707535;Homo sapiens (Human)0.804406Known
Q96SB4SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK16732;Homo sapiens (Human)0.795537Known
Q8TDX7Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK7140609;Homo sapiens (Human)0.79185Known
P54756Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA52044;Homo sapiens (Human)0.788276Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)0.72934Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)0.698646Known
O14730Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK38780;Homo sapiens (Human)0.672853Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)0.669147Known
Q99755Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC ...PIP5K1A8394;Homo sapiens (Human)0.658815Known
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)0.573796Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)0.505446Known
Q13233Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K14214;Homo sapiens (Human)0.49232Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)0.482296Known
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)0.476494Known
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)0.475306Known
Q8IY84Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyNIM1K167359;Homo sapiens (Human)0.474989Known
P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR17046;Homo sapiens (Human)0.43498Known
Q92630Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK28445;Homo sapiens (Human)0.425676Known
Q9P289Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2651765;Homo sapiens (Human)0.376717Known

[23] CHEMBL1241674

Original SMILES:
CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21

Prepared SMILES:
Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C

Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)3.400811
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)3.13448Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.93551Known
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)2.66341Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)2.61123Known
Q92731Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A ...Nuclear hormone receptor family, NR3 subfamilyESR22100;Homo sapiens (Human)2.587972
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)2.58665Known
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)2.55765Known
P42680Tyrosine-protein kinase Tec (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTEC7006;Homo sapiens (Human)2.528773
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)2.504724
P42345Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein ...PI3/PI4-kinase familyMTOR2475;Homo sapiens (Human)2.4771Known
Q9Y463Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1B9149;Homo sapiens (Human)2.433015
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)2.431516
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)2.4196Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)2.3976Known
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)2.37799Known
O00750Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 ...PI3/PI4-kinase familyPIK3C2B5287;Homo sapiens (Human)2.36296Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)2.35557
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)2.32646Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)2.32425Known
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)2.29744Known
O00329Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) ...PI3/PI4-kinase familyPIK3CD5293;Homo sapiens (Human)2.2427Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)2.23879Known
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)2.227328
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)2.22687Known
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)2.217429
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)2.21583Known
P03372Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 ...Nuclear hormone receptor family, NR3 subfamilyESR12099;Homo sapiens (Human)2.1808410
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)2.17447Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)2.15766Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)2.15575Known
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)2.1534Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)2.12511
P78527DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC ...PI3/PI4-kinase familyPRKDC5591;Homo sapiens (Human)2.10681Known
O00311Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamilyCDC78317;Homo sapiens (Human)2.0970812
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)2.09208Known
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)2.07701Known
P04049RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyRAF15894;Homo sapiens (Human)2.0519213
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)2.04696Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)2.03422Known
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)2.02265Known
P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR17046;Homo sapiens (Human)2.00872Known
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)1.978614
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)1.9772615
P24723Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCH5583;Homo sapiens (Human)1.97314Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)1.97063Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)1.96627Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)1.959116
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.94907Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.93649Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)1.9340817
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)1.91996Known
P36894Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1A657;Homo sapiens (Human)1.91902Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.91725Known
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.90074Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)1.90029Known
Q15139Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD15587;Homo sapiens (Human)1.8991418
Q13237cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG25593;Homo sapiens (Human)1.89732Known
Q9BWU1Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1923097;Homo sapiens (Human)1.89328Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)1.88982Known
P37023Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVRL194;Homo sapiens (Human)1.88505Known
Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK18737;Homo sapiens (Human)1.8761319
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)1.86814Known
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)1.8656720
P48730Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein ...Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1D1453;Homo sapiens (Human)1.85089Known
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.85027Known
P42336Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) ...PI3/PI4-kinase familyPIK3CA5290;Homo sapiens (Human)1.84534Known
Q13873Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR2659;Homo sapiens (Human)1.82779Known
Q9P286Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK557144;Homo sapiens (Human)1.80939Known
P48736Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) ...PI3/PI4-kinase familyPIK3CG5294;Homo sapiens (Human)1.8057Known
Q02156Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCE5581;Homo sapiens (Human)1.80315Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)1.80238Known
Q92772Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL28999;Homo sapiens (Human)1.8018121
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.79664Known
O75747Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma (PI3K-C2-gamma) (PtdIns-3-kinase C2 ...PI3/PI4-kinase familyPIK3C2G5288;Homo sapiens (Human)1.78776Known
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)1.78699Known
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)1.7640922
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)1.7583623
P36896Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR1B91;Homo sapiens (Human)1.75301Known
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)1.7444324
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)1.74373Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)1.74102Known
Q9UBF8Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) ...PI3/PI4-kinase family, Type III PI4K subfamilyPI4KB5298;Homo sapiens (Human)1.73266Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)1.72356Known
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)1.7216225
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)1.71334Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)1.7111826
Q9C098Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK385443;Homo sapiens (Human)1.70866Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)1.70679Known
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)1.70206Known
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)1.69435Known
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.69406Known
P41240Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyCSK1445;Homo sapiens (Human)1.68303Known
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)1.6702227
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)1.64836Known
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)1.64044Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)1.64001Known
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)1.6252Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)1.58632Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)1.5802Known
P54764Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA42043;Homo sapiens (Human)1.57512Known
Q15759Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK115600;Homo sapiens (Human)1.5736828
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)1.55755Known
Q8TDC3Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK184446;Homo sapiens (Human)1.54764Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.54629
P54756Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA52044;Homo sapiens (Human)1.54506Known
P49674Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1E102800317;1454;Homo sapiens (Human)1.53654Known
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.536530
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.53179Known
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)1.5250131
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)1.51457Known
O76039Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL56792;Homo sapiens (Human)1.5116332
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)1.50797Known
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.50643Known
P00374Dihydrofolate reductase (EC 1.5.1.3)Dihydrofolate reductase familyDHFR1719;Homo sapiens (Human)1.5064133
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)1.50342Known
P29323Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB22048;Homo sapiens (Human)1.50001Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)1.48966Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)1.485Known
P0C1S8Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) ...Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE2494551;Homo sapiens (Human)1.4844834
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)1.47523Known
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)1.4496535
Q9UIK4Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK223604;Homo sapiens (Human)1.44191Known
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)1.429236
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.4214237
Q9NQU5Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK6106821730;56924;Homo sapiens (Human)1.41968Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.41687Known
Q9BX84Transient receptor potential cation channel subfamily M member 6 (EC ...Protein kinase superfamily, Alpha-type protein kinase family, ALPK subfamily; Transient ...TRPM6140803;Homo sapiens (Human)1.4125738
Q09013Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyDMPK1760;Homo sapiens (Human)1.40786Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)1.40152Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)1.39911Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)1.39395Known
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)1.3918439
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)1.38924Known
P27037Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2A92;Homo sapiens (Human)1.38648Known
P48729Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A11452;Homo sapiens (Human)1.38593Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)1.3676540
O60331Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC ...PIP5K1C23396;Homo sapiens (Human)1.36095Known
Q9UBE8Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...NLK51701;Homo sapiens (Human)1.36055Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)1.35873Known
Q13705Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2B93;Homo sapiens (Human)1.35196Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)1.3516Known
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)1.3476941
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)1.32747Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.32225Known
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)1.31648Known
O15146Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase familyMUSK4593;Homo sapiens (Human)1.3013442
Q04759Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCQ5588;Homo sapiens (Human)1.299243
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)1.28446Known
Q92630Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK28445;Homo sapiens (Human)1.28365Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)1.27364Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)1.27336Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)1.26867Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)1.26611Known
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.26459Known
Q8IWQ3Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK29024;Homo sapiens (Human)1.25042Known
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)1.24584Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)1.24487Known
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)1.2404444
P54753Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB32049;Homo sapiens (Human)1.237445
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)1.2364646
P17252Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCA5578;Homo sapiens (Human)1.2293247
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.2283648
P57078Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK4Homo sapiens (Human)1.2266Known
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)1.2000549
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)1.19957Known
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.1958650
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)1.19163Known
O14936Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; ...CASK8573;Homo sapiens (Human)1.17795Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)1.17761Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)1.17371Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.17272Known
Q8TBX8Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2C79837;Homo sapiens (Human)1.14781Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.1262Known
Q8NI60Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 ...Protein kinase superfamily, ADCK protein kinase familyCOQ8A56997;Homo sapiens (Human)1.12542Known
Q9NYY3Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK210769;Homo sapiens (Human)1.12517Known
P53355Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK11612;Homo sapiens (Human)1.11938Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)1.11893Known
Q6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein ...Protein kinase superfamily, Ser/Thr protein kinase familyDSTYK25778;Homo sapiens (Human)1.11504Known
P42338Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) ...PI3/PI4-kinase familyPIK3CB5291;Homo sapiens (Human)1.115Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)1.11334Known
Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)1.108Known
Q8WTQ7Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK7131890;Homo sapiens (Human)1.10694Known
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)1.09923Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)1.0867Known
Q59H18Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase ...TNNI3K100526835;51086;Homo sapiens (Human)1.08098Known
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)1.07397Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)1.06136Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)1.06026Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)1.04812Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)1.04537Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)1.04361Known
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)1.03487Known
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)1.02822Known
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)1.01168Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)1.00651Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)1.0048Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.00033Known
Q15835Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK16011;Homo sapiens (Human)0.992751Known
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)0.971514Known
P37173TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR27048;Homo sapiens (Human)0.971318Known
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)0.965264Known
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)0.949815Known
Q15569Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyTESK17016;Homo sapiens (Human)0.937714Known
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)0.924922Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)0.91374Known
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)0.90795Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)0.900576Known
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)0.893418Known
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2A815;Homo sapiens (Human)0.886246Known
Q13177Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK25062;Homo sapiens (Human)0.881518Known
P11309Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM15292;Homo sapiens (Human)0.871434Known
Q8NFD2Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyANKK1255239;Homo sapiens (Human)0.862672Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)0.854948Known
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)0.850164Known
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)0.848703Known
Q9BVS4Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK255781;Homo sapiens (Human)0.842679Known
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)0.820233Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)0.817349Known
P45985Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K46416;Homo sapiens (Human)0.808544Known
Q9BUB5MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK18569;Homo sapiens (Human)0.803072Known
Q8WU08Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySTK32A202374;Homo sapiens (Human)0.799868Known
Q9NRM7Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS226524;Homo sapiens (Human)0.796984Known
Q13627Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1A1859;Homo sapiens (Human)0.788291Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)0.780919Known
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)0.766462Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)0.766182Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)0.76512Known
O60885Bromodomain-containing protein 4 (Protein HUNK1)BRD423476;Homo sapiens (Human)0.755597Known
Q8NEV4Myosin-IIIa (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3A53904;Homo sapiens (Human)0.753186Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)0.750689Known
Q9NY57Serine/threonine-protein kinase 32B (EC 2.7.11.1) (Yet another novel kinase 2)Protein kinase superfamily, Ser/Thr protein kinase familySTK32B55351;Homo sapiens (Human)0.731837Known
Q8N752Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A1L122011;Homo sapiens (Human)0.727753Known
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)0.724072Known
Q7KZI7Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK22011;Homo sapiens (Human)0.722016Known
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)0.721431Known
Q9NUW8Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-)Tyrosyl-DNA phosphodiesterase familyTDP155775;Homo sapiens (Human)0.721333Known
Q9Y243RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT310000;Homo sapiens (Human)0.681137Known
P78368Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G21455;Homo sapiens (Human)0.674135Known
Q9H4B4Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK31263;Homo sapiens (Human)0.6627Known
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)0.641907Known
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)0.635473Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)0.634968Known
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)0.628588Known
Q96D53Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase ...Protein kinase superfamily, ADCK protein kinase familyCOQ8B79934;Homo sapiens (Human)0.627853Known
Q13233Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K14214;Homo sapiens (Human)0.625069Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)0.621257Known
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)0.611182Known
P19525Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK25610;Homo sapiens (Human)0.599974Known
Q9Y2K2Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK323387;Homo sapiens (Human)0.560382Known
O94768Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17B9262;Homo sapiens (Human)0.492264Known
Q9HCP0Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G153944;Homo sapiens (Human)0.483637Known
Q9P289Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2651765;Homo sapiens (Human)0.460016Known
Q8WXR4Myosin-IIIb (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3B140469;Homo sapiens (Human)0.392471Known
Q9Y6M4Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G31456;Homo sapiens (Human)0.339684Known

[24] CHEMBL386051

Original SMILES:
CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1

Prepared SMILES:
CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl

P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)3.80739Known
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)3.59859Known
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)3.186041
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)3.106Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)3.075022
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)3.00533
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)2.97256Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)2.90484Known
P42229Signal transducer and activator of transcription 5ATranscription factor STAT familySTAT5A6776;Homo sapiens (Human)2.897844
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)2.86115
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)2.77127Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)2.74681Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)2.71363Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)2.67391Known
P30291Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE17465;Homo sapiens (Human)2.6708Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)2.58537Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)2.57431Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)2.552446
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)2.51846Known
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)2.45722Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)2.45507Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)2.43799Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)2.4028Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)2.394257
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)2.382248
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)2.36716Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)2.362689
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)2.35107Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)2.3416310
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)2.28979Known
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)2.28864Known
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)2.28287Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)2.25244Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)2.2364311
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)2.22865Known
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)2.22666Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)2.2239712
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)2.2206413
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)2.19982Known
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)2.18876Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)2.18457Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)2.18009Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)2.17968Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)2.1763214
P0C1S8Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) ...Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE2494551;Homo sapiens (Human)2.14021Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)2.1354Known
P04049RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyRAF15894;Homo sapiens (Human)2.1282Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)2.12551Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)2.1250115
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)2.11037Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)2.1094416
O75914Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK35063;Homo sapiens (Human)2.0988417
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)2.08898Known
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)2.08433Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)2.04492Known
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)2.03752Known
Q15759Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK115600;Homo sapiens (Human)2.03231Known
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)2.02131Known
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)1.9982618
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)1.99204Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.990419
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.98015Known
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.96087Known
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)1.9596920
Q9UBE8Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...NLK51701;Homo sapiens (Human)1.95602Known
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)1.95037Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)1.9480421
Q9NZJ5Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK39451;Homo sapiens (Human)1.9270422
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)1.91038Known
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)1.87603Known
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)1.8611723
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)1.8598Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)1.85909Known
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)1.85852Known
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)1.8500124
P37023Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVRL194;Homo sapiens (Human)1.84058Known
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.8258925
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)1.81216Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)1.81199Known
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)1.8019726
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)1.79537Known
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)1.789827
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)1.7807228
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)1.7672629
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)1.7567230
Q96D53Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase ...Protein kinase superfamily, ADCK protein kinase familyCOQ8B79934;Homo sapiens (Human)1.7526Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)1.75089Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)1.7492331
Q99640Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyPKMYT19088;Homo sapiens (Human)1.74139Known
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)1.7383532
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.729833
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.72825Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)1.71474Known
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)1.70644Known
Q01538Myelin transcription factor 1 (MyT1) (Myelin transcription factor I) (MyTI) ...MYT1 familyMYT14661;Homo sapiens (Human)1.704734
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)1.70469Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.7018335
Q13153Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK15058;Homo sapiens (Human)1.6980236
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)1.6860837
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.68093Known
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)1.6740938
P54753Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB32049;Homo sapiens (Human)1.67286Known
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.61312Known
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.61238Known
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)1.60297Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)1.6025539
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)1.59483Known
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.58629Known
P54764Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA42043;Homo sapiens (Human)1.58593Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)1.56154Known
Q13705Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2B93;Homo sapiens (Human)1.56055Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.5562440
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)1.5499941
P29323Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB22048;Homo sapiens (Human)1.54233Known
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)1.54201Known
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)1.5348742
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)1.5336Known
Q02779Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K104294;Homo sapiens (Human)1.53359Known
O15146Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase familyMUSK4593;Homo sapiens (Human)1.5278943
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.5275344
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)1.52591Known
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)1.5215845
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.50957Known
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)1.504846
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.49787Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)1.4925347
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.48724Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.48173Known
Q13557Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2D817;Homo sapiens (Human)1.4611248
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)1.4567949
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)1.4564550
Q8TBX8Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2C79837;Homo sapiens (Human)1.43755Known
P27448MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK34140;Homo sapiens (Human)1.43269Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)1.40965Known
Q15569Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyTESK17016;Homo sapiens (Human)1.40649Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)1.39284Known
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.38417Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)1.37879Known
Q9NRP7Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)Protein kinase superfamily, Ser/Thr protein kinase familySTK3627148;Homo sapiens (Human)1.37781Known
P36894Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1A657;Homo sapiens (Human)1.36764Known
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.35917Known
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)1.3554Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.3544Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)1.35218Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)1.34336Known
P51955Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK24751;Homo sapiens (Human)1.33965Known
Q59H18Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase ...TNNI3K100526835;51086;Homo sapiens (Human)1.32006Known
P54756Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA52044;Homo sapiens (Human)1.29377Known
P37173TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR27048;Homo sapiens (Human)1.29377Known
P36896Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR1B91;Homo sapiens (Human)1.29087Known
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)1.27877Known
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)1.25913Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)1.25547Known
P41240Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyCSK1445;Homo sapiens (Human)1.2479Known
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)1.24014Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.22369Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)1.20159Known
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)1.18434Known
P53671LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK23985;Homo sapiens (Human)1.18251Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.17589Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)1.15795Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)1.15278Known
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.13889Known
P45985Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K46416;Homo sapiens (Human)1.12624Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)1.10749Known
Q7KZI7Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK22011;Homo sapiens (Human)1.1056Known
Q9Y6R4Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K44216;Homo sapiens (Human)1.10343Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.0867Known
Q8TDC3Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK184446;Homo sapiens (Human)1.08634Known
Q8NI60Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 ...Protein kinase superfamily, ADCK protein kinase familyCOQ8A56997;Homo sapiens (Human)1.06599Known
P42680Tyrosine-protein kinase Tec (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTEC7006;Homo sapiens (Human)1.06433Known
P0C264Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family ...Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamilySBK3100130827;Homo sapiens (Human)1.05761Known
Q8NG66Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK1179858;Homo sapiens (Human)1.04145Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)1.03948Known
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)1.02799Known
Q9NY57Serine/threonine-protein kinase 32B (EC 2.7.11.1) (Yet another novel kinase 2)Protein kinase superfamily, Ser/Thr protein kinase familySTK32B55351;Homo sapiens (Human)1.02354Known
Q8WU08Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySTK32A202374;Homo sapiens (Human)1.02263Known
Q9Y2K2Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK323387;Homo sapiens (Human)1.00515Known
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)0.986336Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)0.97901Known
Q6P3R8Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK5341676;Homo sapiens (Human)0.96907Known
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)0.94163Known
Q6DT37Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPG55561;Homo sapiens (Human)0.911292Known
P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR17046;Homo sapiens (Human)0.886181Known
P27037Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2A92;Homo sapiens (Human)0.823405Known
Q96PY6Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK14750;Homo sapiens (Human)0.818233Known
Q9Y5S2Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPB9578;Homo sapiens (Human)0.810085Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)0.800165Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)0.795511Known
Q9H4B4Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK31263;Homo sapiens (Human)0.795452Known
Q9H1R3Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK285366;Homo sapiens (Human)0.773426Known
Q8IWQ3Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK29024;Homo sapiens (Human)0.723025Known
Q5VT25Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPA8476;Homo sapiens (Human)0.696515Known
P52564Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K65608;Homo sapiens (Human)0.598338Known
Q16659Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK65597;Homo sapiens (Human)0.561496Known
Q9Y6E0Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK248428;Homo sapiens (Human)0.558446Known
P31152Mitogen-activated protein kinase 4 (MAP kinase 4) (MAPK 4) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK45596;Homo sapiens (Human)0.497249Known
Q9P289Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2651765;Homo sapiens (Human)0.495591Known
Q8IY84Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyNIM1K167359;Homo sapiens (Human)0.432882Known
Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK18737;Homo sapiens (Human)0.271072Known
O00506Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2510494;Homo sapiens (Human)0.215195Known

[25] CHEMBL1230609

Original SMILES:
COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1

Prepared SMILES:
COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F

Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)3.32754Known
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)3.20897Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)3.17811Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)3.09733Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)3.0612Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)3.00614Known
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)2.87985Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)2.87183Known
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)2.856631
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)2.81536Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)2.74353Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)2.55754Known
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)2.45264Known
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)2.445342
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)2.44089Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)2.42451Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)2.42196Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.41225Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)2.41092Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)2.40773
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)2.40111Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)2.39935Known
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)2.39736Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)2.35321Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)2.34737Known
P29323Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB22048;Homo sapiens (Human)2.34559Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)2.29802Known
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)2.28561Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)2.24278Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)2.23255Known
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)2.178494
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)2.16695
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)2.16413Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)2.14897Known
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)2.14796
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)2.147217
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)2.13638Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)2.12949Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)2.10171Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)2.08531Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)2.07867Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)2.06742Known
Q00526Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK31018;Homo sapiens (Human)2.056218
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)2.04083Known
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)2.03632Known
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)2.03039Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)2.0226Known
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)2.02064Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)2.000869
P04049RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyRAF15894;Homo sapiens (Human)1.98261Known
P54764Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA42043;Homo sapiens (Human)1.92964Known
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)1.92939Known
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)1.90547Known
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.89663Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)1.8886Known
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)1.87942Known
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)1.86879Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.85838Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)1.82071Known
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)1.81868Known
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)1.79769Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.78997Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)1.78556Known
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)1.76067Known
Q15759Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK115600;Homo sapiens (Human)1.75333Known
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)1.74614Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)1.74332Known
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.74051Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)1.72882Known
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.7235410
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)1.7062411
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.70036Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)1.69371Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)1.68376Known
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)1.6830212
P54756Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA52044;Homo sapiens (Human)1.67744Known
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.67686Known
P09960Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)Peptidase M1 familyLTA4H4048;Homo sapiens (Human)1.6761713
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)1.6684Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)1.6446Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.62228Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)1.61908Known
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)1.6152Known
O14920Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKB3551;Homo sapiens (Human)1.6063714
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.60059Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)1.59447Known
Q9P289Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2651765;Homo sapiens (Human)1.5788415
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)1.57865Known
Q5VT25Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPA8476;Homo sapiens (Human)1.57145Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)1.56587Known
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)1.56075Known
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)1.55489Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.55471Known
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)1.54198Known
Q99835Smoothened homolog (SMO) (Protein Gx)G-protein coupled receptor Fz/Smo familySMO6608;Homo sapiens (Human)1.53813Known
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)1.53506Known
Q9NWT8Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, ...Mitochondrion-specific ribosomal protein mS38 familyAURKAIP154998;Homo sapiens (Human)1.5248216
Q9BVS4Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK255781;Homo sapiens (Human)1.5247417
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)1.51898Known
P48729Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A11452;Homo sapiens (Human)1.5126218
Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK18737;Homo sapiens (Human)1.50478Known
P089085-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamilyHTR1A3350;Homo sapiens (Human)1.4859519
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)1.4773Known
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.4760320
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)1.47401Known
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.46383Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)1.4621721
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)1.461322
Q8TD08Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15225689;Homo sapiens (Human)1.45875Known
O15146Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase familyMUSK4593;Homo sapiens (Human)1.44875Known
Q96D53Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase ...Protein kinase superfamily, ADCK protein kinase familyCOQ8B79934;Homo sapiens (Human)1.4419123
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)1.4412424
P20794Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyMAK4117;Homo sapiens (Human)1.43849Known
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)1.43727Known
Q9Y2K2Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK323387;Homo sapiens (Human)1.4361225
Q15375Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA72045;Homo sapiens (Human)1.4275Known
P14616Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSRR3645;Homo sapiens (Human)1.42742Known
P51955Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK24751;Homo sapiens (Human)1.4235526
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)1.4230227
P41240Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyCSK1445;Homo sapiens (Human)1.40136Known
P10275Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C ...Nuclear hormone receptor family, NR3 subfamilyAR367;Homo sapiens (Human)1.4010328
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)1.39642Known
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)1.3723629
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.37211Known
P54753Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB32049;Homo sapiens (Human)1.3591Known
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)1.3589730
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.340231
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)1.32964Known
Q9UIK4Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK223604;Homo sapiens (Human)1.3190332
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)1.30751Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.30056Known
P57078Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK4Homo sapiens (Human)1.29934Known
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)1.2967933
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.2927234
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)1.2892735
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.28567Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)1.281336
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)1.26441Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)1.25709Known
Q92772Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL28999;Homo sapiens (Human)1.24107Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)1.23405Known
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)1.2264137
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.22301Known
Q8TBX8Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2C79837;Homo sapiens (Human)1.21696Known
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)1.2168838
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)1.21154Known
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.20964Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)1.20782Known
O14730Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK38780;Homo sapiens (Human)1.206739
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)1.19954Known
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)1.1992540
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)1.1904841
Q9H1R3Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK285366;Homo sapiens (Human)1.18935Known
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)1.18793Known
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)1.17889Known
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)1.17873Known
Q9BWU1Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1923097;Homo sapiens (Human)1.17247Known
P504065-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)G-protein coupled receptor 1 familyHTR63362;Homo sapiens (Human)1.1663242
P28482Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15594;Homo sapiens (Human)1.1662943
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)1.1593244
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.1539445
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)1.15075Known
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.1546
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.14487Known
P35462D(3) dopamine receptor (Dopamine D3 receptor)G-protein coupled receptor 1 familyDRD31814;Homo sapiens (Human)1.1428547
Q9Y463Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1B9149;Homo sapiens (Human)1.1412148
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)1.1298349
Q59H18Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase ...TNNI3K100526835;51086;Homo sapiens (Human)1.11329Known
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)1.1119550
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)1.11157Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)1.10844Known
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)1.10619Known
Q8TD19Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK991754;Homo sapiens (Human)1.10239Known
O15264Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK135603;Homo sapiens (Human)1.1016Known
P49674Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1E102800317;1454;Homo sapiens (Human)1.09289Known
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)1.07072Known
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.07023Known
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)1.04136Known
O00506Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2510494;Homo sapiens (Human)1.03958Known
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.03646Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)1.01966Known
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)1.01903Known
O94921Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK145218;Homo sapiens (Human)1.00404Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)0.999769Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)0.983952Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)0.977669Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)0.977656Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)0.975605Known
Q96Q40Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1565061;Homo sapiens (Human)0.973458Known
Q8IVW4Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine-protein kinase NKIAMRE)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL351265;Homo sapiens (Human)0.95123Known
Q07002Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK185129;Homo sapiens (Human)0.941039Known
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)0.935929Known
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)0.935837Known
Q00537Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK175128;Homo sapiens (Human)0.932276Known
Q9Y6R4Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K44216;Homo sapiens (Human)0.915632Known
P53778Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK126300;Homo sapiens (Human)0.906494Known
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)0.89907Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)0.884314Known
Q9UQ88Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK11A728642;Homo sapiens (Human)0.881605Known
Q9NRP7Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)Protein kinase superfamily, Ser/Thr protein kinase familySTK3627148;Homo sapiens (Human)0.877177Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)0.8625Known
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)0.860304Known
Q6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein ...Protein kinase superfamily, Ser/Thr protein kinase familyDSTYK25778;Homo sapiens (Human)0.857337Known
P21127Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK11B984;Homo sapiens (Human)0.851824Known
Q9UBE8Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...NLK51701;Homo sapiens (Human)0.831689Known
Q15569Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyTESK17016;Homo sapiens (Human)0.822575Known
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)0.811296Known
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)0.801438Known
Q9Y5S2Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPB9578;Homo sapiens (Human)0.793789Known
Q02779Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K104294;Homo sapiens (Human)0.793528Known
O15111Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyCHUK1147;Homo sapiens (Human)0.79292Known
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)0.789975Known
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)0.789391Known
Q9BQI3Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK127102;Homo sapiens (Human)0.780174Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)0.755448Known
Q9BUB5MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK18569;Homo sapiens (Human)0.752506Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)0.737156Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)0.732115Known
Q92630Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK28445;Homo sapiens (Human)0.696278Known
P53671LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK23985;Homo sapiens (Human)0.668334Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)0.654464Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)0.650491Known
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)0.644775Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)0.617595Known
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)0.605008Known
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)0.601763Known
P546465'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA25563;Homo sapiens (Human)0.599941Known
Q6DT37Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPG55561;Homo sapiens (Human)0.596503Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)0.594789Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)0.587522Known
O75914Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK35063;Homo sapiens (Human)0.544313Known
P42680Tyrosine-protein kinase Tec (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTEC7006;Homo sapiens (Human)0.531113Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)0.524245Known
Q8WXR4Myosin-IIIb (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3B140469;Homo sapiens (Human)0.50335Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)0.495492Known
O76039Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL56792;Homo sapiens (Human)0.452749Known
Q8NFD2Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyANKK1255239;Homo sapiens (Human)0.451367Known
O14578Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)Protein kinase superfamily, AGC Ser/Thr protein kinase familyCIT11113;Homo sapiens (Human)0.41522Known
Q8NEV4Myosin-IIIa (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3A53904;Homo sapiens (Human)0.406023Known
Q14012Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK18536;Homo sapiens (Human)0.361556Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)0.312623Known
P57058Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyHUNK30811;Homo sapiens (Human)0.269921Known

[26] CHEMBL1993661

Original SMILES:
CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl

Prepared SMILES:
COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC

O43570Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA12771;Homo sapiens (Human)3.321081
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)2.964132
P00374Dihydrofolate reductase (EC 1.5.1.3)Dihydrofolate reductase familyDHFR1719;Homo sapiens (Human)2.616933
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)2.480494
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)2.459095
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)2.354776
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)2.267077
P51679C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) ...G-protein coupled receptor 1 familyCCR41233;Homo sapiens (Human)2.201438
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)2.174759
Q16790Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA9768;Homo sapiens (Human)2.1499710
P504065-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)G-protein coupled receptor 1 familyHTR63362;Homo sapiens (Human)2.1058211
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)2.074512
P10275Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C ...Nuclear hormone receptor family, NR3 subfamilyAR367;Homo sapiens (Human)2.05713
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)1.9993614
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.98615
P42229Signal transducer and activator of transcription 5ATranscription factor STAT familySTAT5A6776;Homo sapiens (Human)1.9834616
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)1.959717
P34913Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) ...AB hydrolase superfamily, Epoxide hydrolase familyEPHX22053;Homo sapiens (Human)1.9402818
P43166Carbonic anhydrase 7 (EC 4.2.1.1) (Carbonate dehydratase VII) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA7766;Homo sapiens (Human)1.9338219
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)1.9285420
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.9242221
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.9137622
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)1.8571523
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.8421324
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)1.8206825
P21917D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)G-protein coupled receptor 1 familyDRD41815;Homo sapiens (Human)1.8041726
P41594Metabotropic glutamate receptor 5 (mGluR5)G-protein coupled receptor 3 familyGRM52915;Homo sapiens (Human)1.7991227
P49286Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)G-protein coupled receptor 1 familyMTNR1B4544;Homo sapiens (Human)1.7503328
P089085-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamilyHTR1A3350;Homo sapiens (Human)1.7413829
Q9ULX7Carbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA1423632;Homo sapiens (Human)1.7307330
P460985-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) ...Ligand-gated ion channel (TC 1.A.9) family, 5-hydroxytryptamine receptor (TC 1.A.9.2) ...HTR3A3359;Homo sapiens (Human)1.7043931
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)1.7021232
P05067Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) ...APP familyAPP351;Homo sapiens (Human)1.6770633
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)1.6747434
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)1.6346235
P00742Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved ...Peptidase S1 familyF102159;Homo sapiens (Human)1.6265136
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)1.5884737
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.5829938
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)1.5474539
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)1.5170340
P10145Interleukin-8 (IL-8) (C-X-C motif chemokine 8) (Chemokine (C-X-C motif) ligand ...Intercrine alpha (chemokine CxC) familyCXCL83576;Homo sapiens (Human)1.5127941
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.4661642
Q07343cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.53) (DPDE4) (PDE32)Cyclic nucleotide phosphodiesterase family, PDE4 subfamilyPDE4B5142;Homo sapiens (Human)1.435143
P35462D(3) dopamine receptor (Dopamine D3 receptor)G-protein coupled receptor 1 familyDRD31814;Homo sapiens (Human)1.4304944
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)1.4190645
P27338Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) ...Flavin monoamine oxidase familyMAOB4129;Homo sapiens (Human)1.3516346
Q136395-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4)G-protein coupled receptor 1 familyHTR43360;Homo sapiens (Human)1.3478947
P35354Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) ...Prostaglandin G/H synthase familyPTGS25743;Homo sapiens (Human)1.3131248
P27815cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.53) (DPDE2) (PDE46)Cyclic nucleotide phosphodiesterase family, PDE4 subfamilyPDE4A5141;Homo sapiens (Human)1.302249
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.264850

[27] CHEMBL1987034

Original SMILES:
N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1

Prepared SMILES:
N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N

O43570Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA12771;Homo sapiens (Human)2.922481
P00374Dihydrofolate reductase (EC 1.5.1.3)Dihydrofolate reductase familyDHFR1719;Homo sapiens (Human)2.757352
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)2.728243
P11511Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen ...Cytochrome P450 familyCYP19A11588;Homo sapiens (Human)2.577574
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)2.450825
P43166Carbonic anhydrase 7 (EC 4.2.1.1) (Carbonate dehydratase VII) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA7766;Homo sapiens (Human)2.39756
P504065-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)G-protein coupled receptor 1 familyHTR63362;Homo sapiens (Human)2.349057
P00746Complement factor D (EC 3.4.21.46) (Adipsin) (C3 convertase activator) (Properdin ...Peptidase S1 familyCFD1675;Homo sapiens (Human)2.182128
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)2.12679
P42229Signal transducer and activator of transcription 5ATranscription factor STAT familySTAT5A6776;Homo sapiens (Human)2.1236810
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)2.1070511
P51679C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) ...G-protein coupled receptor 1 familyCCR41233;Homo sapiens (Human)2.0370312
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)1.9388813
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)1.9370414
P05067Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) ...APP familyAPP351;Homo sapiens (Human)1.9243815
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.9202316
P35372Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid ...G-protein coupled receptor 1 familyOPRM14988;Homo sapiens (Human)1.8683617
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)1.8647918
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.8402819
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.8279120
P10275Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C ...Nuclear hormone receptor family, NR3 subfamilyAR367;Homo sapiens (Human)1.7860521
Q9ULX7Carbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA1423632;Homo sapiens (Human)1.7252522
P41145Kappa-type opioid receptor (K-OR-1) (KOR-1)G-protein coupled receptor 1 familyOPRK14986;Homo sapiens (Human)1.7133123
P31645Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family ...Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamilySLC6A46532;Homo sapiens (Human)1.7124424
P41594Metabotropic glutamate receptor 5 (mGluR5)G-protein coupled receptor 3 familyGRM52915;Homo sapiens (Human)1.6780625
P09960Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)Peptidase M1 familyLTA4H4048;Homo sapiens (Human)1.6355126
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.633927
P03372Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 ...Nuclear hormone receptor family, NR3 subfamilyESR12099;Homo sapiens (Human)1.5996228
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)1.5915329
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.585230
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.5840431
P00915Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA1759;Homo sapiens (Human)1.5603432
P35462D(3) dopamine receptor (Dopamine D3 receptor)G-protein coupled receptor 1 familyDRD31814;Homo sapiens (Human)1.5262833
P089085-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamilyHTR1A3350;Homo sapiens (Human)1.5055834
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)1.5011635
Q16790Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA9768;Homo sapiens (Human)1.4823836
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.4658137
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.4585638
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)1.4565939
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)1.4481340
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)1.4066941
P15538Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid ...Cytochrome P450 familyCYP11B11584;Homo sapiens (Human)1.3878542
P21917D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)G-protein coupled receptor 1 familyDRD41815;Homo sapiens (Human)1.3783443
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)1.3455744
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)1.3315345
P00742Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved ...Peptidase S1 familyF102159;Homo sapiens (Human)1.2803846
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)1.2800247
P43235Cathepsin K (EC 3.4.22.38) (Cathepsin O) (Cathepsin O2) (Cathepsin X)Peptidase C1 familyCTSK1513;Homo sapiens (Human)1.2617248
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)1.2613749
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)1.230950

[28] CHEMBL5416410

Original SMILES:
Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O

Prepared SMILES:
OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl

O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)3.20391Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)3.13395Known
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)3.045411
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.93341Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)2.87787Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)2.87543Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)2.848892
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)2.83059Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)2.65004Known
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)2.63101Known
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)2.60675Known
Q01538Myelin transcription factor 1 (MyT1) (Myelin transcription factor I) (MyTI) ...MYT1 familyMYT14661;Homo sapiens (Human)2.56372Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)2.5511Known
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)2.47651Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)2.43113Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)2.35778Known
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)2.31298Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)2.29853Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)2.2946Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)2.26103Known
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)2.25209Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)2.23904Known
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)2.22341Known
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)2.220293
Q15375Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA72045;Homo sapiens (Human)2.216224
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)2.21297Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)2.1909Known
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)2.16296Known
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)2.15356Known
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)2.150885
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)2.120616
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)2.115497
Q15759Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK115600;Homo sapiens (Human)2.048318
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)2.02774Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)2.01259Known
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)2.00024Known
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.99549Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)1.994869
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.975Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.9637Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)1.9559Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)1.9271510
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)1.90083Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)1.89406Known
Q9Y2K2Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK323387;Homo sapiens (Human)1.86168Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)1.85769Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)1.8524311
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)1.82675Known
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.82289Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)1.8190812
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)1.8166213
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)1.79708Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.7946114
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)1.74555Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)1.7187515
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)1.6999116
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)1.69145Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.673117
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)1.6071818
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)1.6044619
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)1.5943620
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)1.5938821
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)1.5674322
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.55598Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)1.554Known
Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)1.5519823
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.5510924
P54753Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB32049;Homo sapiens (Human)1.53269Known
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)1.5313225
P78527DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC ...PI3/PI4-kinase familyPRKDC5591;Homo sapiens (Human)1.5180326
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)1.4900127
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)1.4527328
P34998Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor ...G-protein coupled receptor 2 familyCRHR1104909134;1394;Homo sapiens (Human)1.4453129
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)1.44188Known
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)1.43693Known
P11309Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM15292;Homo sapiens (Human)1.4210330
Q52WX2Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySBK1388228;Homo sapiens (Human)1.40832Known
P29323Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB22048;Homo sapiens (Human)1.40288Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)1.4015631
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.3995932
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)1.3983933
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)1.39802Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)1.39504Known
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.38563Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.38092Known
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.3682134
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.3549435
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.3470636
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)1.33295Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.32883Known
P49674Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1E102800317;1454;Homo sapiens (Human)1.3262137
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)1.3250438
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)1.31976Known
P54756Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA52044;Homo sapiens (Human)1.3073Known
P48449Lanosterol synthase (EC 5.4.99.7) (2,3-epoxysqualene--lanosterol cyclase) (Oxidosqualene--lanosterol cyclase) (OSC) (hOSC)Terpene cyclase/mutase familyLSS4047;Homo sapiens (Human)1.3036839
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.28666Known
P04049RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyRAF15894;Homo sapiens (Human)1.25991Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)1.2583840
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)1.2579641
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.25191Known
Q8NG66Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK1179858;Homo sapiens (Human)1.24753Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.2471442
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)1.2341343
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)1.22303Known
P36896Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR1B91;Homo sapiens (Human)1.2180144
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)1.21371Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.208545
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)1.2038346
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.1986947
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)1.1971648
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)1.188949
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)1.1882150
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)1.18Known
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)1.17865Known
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)1.17515Known
P36894Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1A657;Homo sapiens (Human)1.1735Known
P42680Tyrosine-protein kinase Tec (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTEC7006;Homo sapiens (Human)1.1483Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)1.11867Known
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)1.10672Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)1.09341Known
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)1.0819Known
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)1.07288Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)1.0673Known
P51955Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK24751;Homo sapiens (Human)1.06322Known
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)1.05959Known
P54764Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA42043;Homo sapiens (Human)1.05656Known
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)1.03025Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)1.02996Known
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.02624Known
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)0.985528Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)0.971547Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)0.970347Known
Q9H1R3Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK285366;Homo sapiens (Human)0.951746Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)0.927158Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)0.906139Known
Q5VT25Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPA8476;Homo sapiens (Human)0.895115Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)0.876055Known
Q99640Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyPKMYT19088;Homo sapiens (Human)0.87321Known
P41240Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyCSK1445;Homo sapiens (Human)0.867031Known
P53671LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK23985;Homo sapiens (Human)0.834482Known
O43781Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1) (Regulatory erythroid kinase) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK38444;Homo sapiens (Human)0.829899Known
Q15569Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyTESK17016;Homo sapiens (Human)0.828295Known
P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR17046;Homo sapiens (Human)0.822428Known
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)0.821087Known
Q09013Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyDMPK1760;Homo sapiens (Human)0.81012Known
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)0.800961Known
P27037Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2A92;Homo sapiens (Human)0.768218Known
Q02779Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K104294;Homo sapiens (Human)0.721418Known
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)0.710259Known
Q86Y07Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, VRK subfamilyVRK27444;Homo sapiens (Human)0.704354Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)0.683473Known
Q59H18Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase ...TNNI3K100526835;51086;Homo sapiens (Human)0.657616Known
Q9UBE8Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...NLK51701;Homo sapiens (Human)0.631802Known
P0C1S8Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) ...Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE2494551;Homo sapiens (Human)0.62094Known
Q9NRP7Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)Protein kinase superfamily, Ser/Thr protein kinase familySTK3627148;Homo sapiens (Human)0.591964Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)0.577304Known
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)0.559314Known
Q8NI60Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 ...Protein kinase superfamily, ADCK protein kinase familyCOQ8A56997;Homo sapiens (Human)0.462147Known
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)0.440977Known
Q9Y6R4Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K44216;Homo sapiens (Human)0.415457Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)0.407899Known
P84022Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers ...Dwarfin/SMAD familySMAD34088;Homo sapiens (Human)0.402391Known
Q9NUW8Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-)Tyrosyl-DNA phosphodiesterase familyTDP155775;Homo sapiens (Human)0.272093Known
O00506Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2510494;Homo sapiens (Human)0.238235Known
P08684Cytochrome P450 3A4 (EC 1.14.14.-) (1,8-cineole 2-exo-monooxygenase) (EC 1.14.14.56) (Albendazole ...Cytochrome P450 familyCYP3A41576;Homo sapiens (Human)0.222163Known

[29] CHEMBL379218

Original SMILES:
Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12

Prepared SMILES:
N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2

Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)3.61977Known
P31749RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT1207;Homo sapiens (Human)3.42651Known
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)3.307771
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)3.179972
P17252Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCA5578;Homo sapiens (Human)3.06163
Q9Y243RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT310000;Homo sapiens (Human)2.9979Known
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)2.910434
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)2.792355
P24723Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCH5583;Homo sapiens (Human)2.76965Known
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)2.606996
P11309Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM15292;Homo sapiens (Human)2.6028Known
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)2.56764Known
Q00535Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK51020;Homo sapiens (Human)2.506867
P31751RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT2208;Homo sapiens (Human)2.46109Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)2.41398
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)2.380879
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)2.34539Known
O76039Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL56792;Homo sapiens (Human)2.29756Known
Q9BWU1Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1923097;Homo sapiens (Human)2.28209Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)2.2455510
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)2.13515Known
P05771Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCB5579;Homo sapiens (Human)2.1035911
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)2.09782Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)2.0708412
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)2.04335Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)2.03671Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)2.02324Known
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)2.01551Known
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)2.002413
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)1.9813Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)1.9731914
Q05513Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCZ5590;Homo sapiens (Human)1.8943515
Q04759Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCQ5588;Homo sapiens (Human)1.88891Known
P20794Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyMAK4117;Homo sapiens (Human)1.8846116
O75914Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK35063;Homo sapiens (Human)1.878517
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)1.86824Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)1.8535418
P09960Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)Peptidase M1 familyLTA4H4048;Homo sapiens (Human)1.8150219
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)1.789520
Q13627Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1A1859;Homo sapiens (Human)1.77247Known
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)1.76423Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)1.7633921
Q13153Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK15058;Homo sapiens (Human)1.74126Known
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)1.72187Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)1.7194922
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)1.7043423
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)1.70181Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.7004224
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)1.6802625
Q13237cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG25593;Homo sapiens (Human)1.67851Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)1.6762626
Q9C098Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK385443;Homo sapiens (Human)1.6699327
O00329Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) ...PI3/PI4-kinase familyPIK3CD5293;Homo sapiens (Human)1.6658828
Q00526Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK31018;Homo sapiens (Human)1.6598Known
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)1.6596829
Q9UQ88Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK11A728642;Homo sapiens (Human)1.6527230
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)1.6517831
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)1.6472132
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.6448533
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)1.62947Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.6236234
Q13177Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK25062;Homo sapiens (Human)1.61878Known
Q9BRS2Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK183732;Homo sapiens (Human)1.61408Known
O14730Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK38780;Homo sapiens (Human)1.60419Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.60195Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)1.6005935
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)1.59706Known
O14578Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)Protein kinase superfamily, AGC Ser/Thr protein kinase familyCIT11113;Homo sapiens (Human)1.59574Known
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)1.5813336
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)1.5806537
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)1.56958Known
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)1.5687938
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)1.56347Known
O14936Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; ...CASK8573;Homo sapiens (Human)1.5577439
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)1.5551140
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)1.55477Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)1.54128Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.5333641
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.5195342
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)1.5172843
P37173TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR27048;Homo sapiens (Human)1.4978544
O94768Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17B9262;Homo sapiens (Human)1.4941Known
Q99755Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC ...PIP5K1A8394;Homo sapiens (Human)1.49029Known
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.4798145
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)1.4696146
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.46846Known
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)1.46398Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)1.46005Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)1.45906Known
P21127Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK11B984;Homo sapiens (Human)1.4588547
P51817cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKX5613;Homo sapiens (Human)1.45851Known
Q9Y463Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1B9149;Homo sapiens (Human)1.44827Known
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.4275948
Q9P286Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK557144;Homo sapiens (Human)1.42006Known
P03372Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 ...Nuclear hormone receptor family, NR3 subfamilyESR12099;Homo sapiens (Human)1.4190949
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)1.4166350
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)1.41015Known
Q86YV6Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4340156;Homo sapiens (Human)1.39686Known
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)1.39404Known
Q16816Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG15260;Homo sapiens (Human)1.38715Known
O94921Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK145218;Homo sapiens (Human)1.38594Known
Q5VT25Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPA8476;Homo sapiens (Human)1.38139Known
P53355Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK11612;Homo sapiens (Human)1.35835Known
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)1.34607Known
P22694cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACB5567;Homo sapiens (Human)1.34337Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.33901Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)1.33331Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.31648Known
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.31446Known
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)1.30213Known
Q16566Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK4814;Homo sapiens (Human)1.29559Known
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.2941Known
P48729Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A11452;Homo sapiens (Human)1.28037Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)1.27968Known
Q9UIK4Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK223604;Homo sapiens (Human)1.27476Known
P48730Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein ...Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1D1453;Homo sapiens (Human)1.26571Known
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)1.26383Known
Q02156Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCE5581;Homo sapiens (Human)1.26199Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)1.26048Known
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)1.25723Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)1.24111Known
P49761Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK31198;Homo sapiens (Human)1.23954Known
P78362SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK26733;Homo sapiens (Human)1.23672Known
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)1.23532Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.20506Known
Q92630Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK28445;Homo sapiens (Human)1.19968Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.19627Known
Q8TD08Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15225689;Homo sapiens (Human)1.18062Known
Q16512Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN15585;Homo sapiens (Human)1.16063Known
P49674Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1E102800317;1454;Homo sapiens (Human)1.13773Known
Q9UBF8Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) ...PI3/PI4-kinase family, Type III PI4K subfamilyPI4KB5298;Homo sapiens (Human)1.1337Known
Q9UEE5Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17A9263;Homo sapiens (Human)1.13056Known
Q05655Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCD5580;Homo sapiens (Human)1.12375Known
P28482Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15594;Homo sapiens (Human)1.12247Known
P49137MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMAPKAPK29261;Homo sapiens (Human)1.11422Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)1.09197Known
Q96SB4SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK16732;Homo sapiens (Human)1.091Known
P78356Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2B8396;Homo sapiens (Human)1.08601Known
Q00537Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK175128;Homo sapiens (Human)1.07112Known
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)1.06987Known
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.06622Known
Q9NQU5Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK6106821730;56924;Homo sapiens (Human)1.06544Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)1.06441Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)1.05366Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)1.05307Known
Q92772Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL28999;Homo sapiens (Human)1.05133Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)1.0506Known
Q9Y6M4Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G31456;Homo sapiens (Human)1.01544Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)1.0062Known
Q13523Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familyPRPF4B8899;Homo sapiens (Human)1.00368Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)0.959009Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)0.951977Known
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)0.94439Known
Q13976cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG15592;Homo sapiens (Human)0.941645Known
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)0.938326Known
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2A815;Homo sapiens (Human)0.928918Known
Q09013Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyDMPK1760;Homo sapiens (Human)0.915174Known
Q8IVW4Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine-protein kinase NKIAMRE)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL351265;Homo sapiens (Human)0.90952Known
Q13557Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2D817;Homo sapiens (Human)0.89567Known
Q9Y5S2Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPB9578;Homo sapiens (Human)0.895003Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)0.882721Known
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)0.882468Known
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)0.872335Known
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)0.870114Known
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)0.867387Known
Q96BR1Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK3100533105;23678;Homo sapiens (Human)0.866959Known
P05129Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCG5582;Homo sapiens (Human)0.860409Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)0.851879Known
Q07002Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK185129;Homo sapiens (Human)0.843984Known
P78368Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G21455;Homo sapiens (Human)0.839198Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)0.837345Known
Q13555Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2G818;Homo sapiens (Human)0.829555Known
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)0.81091Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)0.810518Known
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)0.807779Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)0.807334Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)0.80487Known
Q9HCP0Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G153944;Homo sapiens (Human)0.732084Known
Q9NRM7Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS226524;Homo sapiens (Human)0.724495Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)0.718157Known
Q86Y07Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, VRK subfamilyVRK27444;Homo sapiens (Human)0.702197Known
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)0.667495Known
Q8WTQ7Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK7131890;Homo sapiens (Human)0.62334Known
Q96Q40Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1565061;Homo sapiens (Human)0.61477Known
Q9BVS4Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK255781;Homo sapiens (Human)0.583928Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)0.556296Known
O95835Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS19113;Homo sapiens (Human)0.537855Known
Q6DT37Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPG55561;Homo sapiens (Human)0.531492Known
Q13554Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2B816;Homo sapiens (Human)0.44518Known
Q8N752Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A1L122011;Homo sapiens (Human)0.428648Known
P19525Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK25610;Homo sapiens (Human)0.306054Known

[30] CHEMBL1983111

Original SMILES:
CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12

Prepared SMILES:
CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F

Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)3.50109Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)3.17012Known
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)2.805581
P49286Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)G-protein coupled receptor 1 familyMTNR1B4544;Homo sapiens (Human)2.697982
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)2.67832Known
O00311Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamilyCDC78317;Homo sapiens (Human)2.60026Known
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)2.53351Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)2.45443Known
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)2.423513
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)2.41078Known
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)2.38577Known
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)2.364554
Q00535Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK51020;Homo sapiens (Human)2.33268Known
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)2.33047Known
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)2.27172Known
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)2.24242Known
P27448MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK34140;Homo sapiens (Human)2.23591Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)2.22476Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)2.21434Known
P48039Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)G-protein coupled receptor 1 familyMTNR1A4543;Homo sapiens (Human)2.212115
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)2.20124Known
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)2.15308Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)2.143396
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)2.114877
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)2.10246Known
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)2.10172Known
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)2.0816Known
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)2.070558
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)2.04062Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)2.037989
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)2.0376710
Q96PF2Testis-specific serine/threonine-protein kinase 2 (TSK-2) (TSK2) (TSSK-2) (Testis-specific kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK223617;Homo sapiens (Human)2.02857Known
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)2.0249Known
Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)2.0146111
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)2.00833Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.00133Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)1.99096Known
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)1.98863Known
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)1.957312
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)1.9347113
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)1.92025Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)1.9146714
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.9059515
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)1.9016716
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)1.8807317
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.8795118
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)1.87132Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)1.86953Known
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.86118Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)1.8329619
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.80938Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)1.79248Known
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)1.7916120
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.78699Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)1.75635Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)1.75283Known
P28482Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15594;Homo sapiens (Human)1.74999Known
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.74797Known
Q15139Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD15587;Homo sapiens (Human)1.7311621
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)1.72971Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)1.72742Known
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)1.72532Known
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)1.725Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.725Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.72319Known
Q13627Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1A1859;Homo sapiens (Human)1.70582Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)1.691722
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)1.6916723
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)1.68199Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)1.6633124
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.66088Known
Q15759Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK115600;Homo sapiens (Human)1.6600125
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)1.65947Known
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)1.64485Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)1.63937Known
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)1.6392726
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)1.6354627
P11309Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM15292;Homo sapiens (Human)1.6325628
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)1.6254329
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)1.6174630
Q9BXA7Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK1B83942;Homo sapiens (Human)1.61726Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)1.6165331
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.6152132
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)1.59948Known
P24385G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 ...Cyclin family, Cyclin D subfamilyCCND1595;Homo sapiens (Human)1.5876233
Q9Y243RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT310000;Homo sapiens (Human)1.5736134
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.56517Known
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)1.5592235
Q8IW41MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMAPKAPK58550;Homo sapiens (Human)1.5560936
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)1.55498Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)1.5541937
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)1.5493938
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)1.5400139
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)1.53662Known
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.53618Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)1.53046Known
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)1.52689Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.52491Known
P34913Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) ...AB hydrolase superfamily, Epoxide hydrolase familyEPHX22053;Homo sapiens (Human)1.5212140
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.5180641
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)1.51416Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)1.5120642
Q04759Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCQ5588;Homo sapiens (Human)1.50957Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.50903Known
Q9UEE5Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17A9263;Homo sapiens (Human)1.50368Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.49835Known
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)1.4863Known
Q7KZI7Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK22011;Homo sapiens (Human)1.4795143
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.47126Known
P31749RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT1207;Homo sapiens (Human)1.4618844
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)1.4588Known
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)1.45496Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)1.4549445
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.45197Known
Q8TDC3Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK184446;Homo sapiens (Human)1.45Known
P05771Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCB5579;Homo sapiens (Human)1.4478346
Q9H4B4Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK31263;Homo sapiens (Human)1.4467347
P48729Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A11452;Homo sapiens (Human)1.4440648
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)1.4408449
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.4320150
P51957Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK46787;Homo sapiens (Human)1.42396Known
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)1.3997Known
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)1.38643Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.37942Known
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)1.3481Known
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)1.32149Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)1.3197Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)1.31663Known
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.29816Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)1.26001Known
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)1.25862Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)1.25537Known
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)1.24795Known
O43781Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1) (Regulatory erythroid kinase) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK38444;Homo sapiens (Human)1.24378Known
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.22434Known
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)1.19965Known
P53350Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK15347;Homo sapiens (Human)1.19738Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)1.17294Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)1.17184Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)1.15095Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)1.11842Known
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)1.09496Known
Q96SB4SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK16732;Homo sapiens (Human)1.07397Known
Q13555Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2G818;Homo sapiens (Human)1.04721Known
O15264Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK135603;Homo sapiens (Human)1.04652Known
Q13557Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2D817;Homo sapiens (Human)1.04575Known
Q9Y463Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1B9149;Homo sapiens (Human)1.03108Known
Q9HBY8Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2)Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK210110;Homo sapiens (Human)1.025Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.01344Known
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)1.00598Known
P34947G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK52869;Homo sapiens (Human)0.984568Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)0.964137Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)0.961623Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)0.913891Known
P42679Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic ...Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyMATK4145;Homo sapiens (Human)0.910606Known
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2A815;Homo sapiens (Human)0.901977Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)0.874745Known
P48730Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein ...Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1D1453;Homo sapiens (Human)0.87063Known
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)0.854632Known
P53778Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK126300;Homo sapiens (Human)0.831721Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)0.802159Known
Q05655Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCD5580;Homo sapiens (Human)0.796804Known
P51955Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK24751;Homo sapiens (Human)0.792212Known
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)0.780426Known
P05129Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCG5582;Homo sapiens (Human)0.75Known
Q9HCP0Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G153944;Homo sapiens (Human)0.735667Known
P51817cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKX5613;Homo sapiens (Human)0.734143Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)0.717735Known
P78368Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G21455;Homo sapiens (Human)0.711031Known
O15075Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK19201;Homo sapiens (Human)0.605999Known
Q13554Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2B816;Homo sapiens (Human)0.473713Known
Q5VT25Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPA8476;Homo sapiens (Human)0.425Known

[31] CHEMBL1986943

Original SMILES:
OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1

Prepared SMILES:
OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2

Q92731Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A ...Nuclear hormone receptor family, NR3 subfamilyESR22100;Homo sapiens (Human)3.284661
P05067Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) ...APP familyAPP351;Homo sapiens (Human)2.844282
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)2.795883
P03372Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 ...Nuclear hormone receptor family, NR3 subfamilyESR12099;Homo sapiens (Human)2.716334
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)2.651035
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)2.611076
P43681Neuronal acetylcholine receptor subunit alpha-4Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) ...CHRNA41137;Homo sapiens (Human)2.602237
P21917D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)G-protein coupled receptor 1 familyDRD41815;Homo sapiens (Human)2.456228
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)2.393859
P00742Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved ...Peptidase S1 familyF102159;Homo sapiens (Human)2.2992610
P04278Sex hormone-binding globulin (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding ...SHBG6462;Homo sapiens (Human)2.1827811
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)2.0952212
Q99705Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein ...G-protein coupled receptor 1 familyMCHR12847;Homo sapiens (Human)2.0511513
P14625Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 ...Heat shock protein 90 familyHSP90B17184;Homo sapiens (Human)2.0486514
P41594Metabotropic glutamate receptor 5 (mGluR5)G-protein coupled receptor 3 familyGRM52915;Homo sapiens (Human)2.0194815
P415955-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)G-protein coupled receptor 1 familyHTR2B3357;Homo sapiens (Human)1.9594516
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)1.9502717
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.9498918
P08238Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 ...Heat shock protein 90 familyHSP90AB13326;Homo sapiens (Human)1.9405819
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)1.870920
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.8206421
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)1.8188722
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.8135423
O00141Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1)Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK16446;Homo sapiens (Human)1.7692424
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)1.7437625
P07550Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB2 sub-subfamilyADRB2154;Homo sapiens (Human)1.7033126
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)1.6776427
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)1.6577128
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.6127329
P283355-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) ...G-protein coupled receptor 1 familyHTR2C3358;Homo sapiens (Human)1.5718830
P09960Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)Peptidase M1 familyLTA4H4048;Homo sapiens (Human)1.5704931
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)1.5474132
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)1.5268333
Q13535Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) ...PI3/PI4-kinase family, ATM subfamilyATR545;Homo sapiens (Human)1.5233534
P36544Neuronal acetylcholine receptor subunit alpha-7Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) ...CHRNA71139;89832;Homo sapiens (Human)1.5111935
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.5098336
Q99558Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K149020;Homo sapiens (Human)1.4768837
P05412Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (V-jun ...BZIP family, Jun subfamilyJUN3725;Homo sapiens (Human)1.4685238
P34972Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)G-protein coupled receptor 1 familyCNR21269;Homo sapiens (Human)1.4636939
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)1.4154240
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)1.4122141
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.3909842
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.3691443
P30542Adenosine receptor A1G-protein coupled receptor 1 familyADORA1134;Homo sapiens (Human)1.3568644
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)1.3513145
Q13255Metabotropic glutamate receptor 1 (mGluR1)G-protein coupled receptor 3 familyGRM12911;Homo sapiens (Human)1.3486246
P29274Adenosine receptor A2aG-protein coupled receptor 1 familyADORA2A135;Homo sapiens (Human)1.342347
P31751RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT2208;Homo sapiens (Human)1.2891748
P00374Dihydrofolate reductase (EC 1.5.1.3)Dihydrofolate reductase familyDHFR1719;Homo sapiens (Human)1.2891149
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)1.288950

[32] CHEMBL1980995

Original SMILES:
CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4

Prepared SMILES:
CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O

P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)3.109351
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)2.963322
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)2.949663
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)2.901924
P05771Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCB5579;Homo sapiens (Human)2.74885
Q16584Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K114296;Homo sapiens (Human)2.691436
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)2.684157
Q9P0L2Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK14139;Homo sapiens (Human)2.579268
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)2.577739
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)2.573510
Q02156Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCE5581;Homo sapiens (Human)2.3603211
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)2.3221312
P41597C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) ...G-protein coupled receptor 1 familyCCR2729230;Homo sapiens (Human)2.2804513
Q13490Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of ...IAP familyBIRC2329;Homo sapiens (Human)2.2758314
Q02779Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K104294;Homo sapiens (Human)2.2642715
Q05655Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCD5580;Homo sapiens (Human)2.1669216
P34972Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)G-protein coupled receptor 1 familyCNR21269;Homo sapiens (Human)2.1320817
P05129Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCG5582;Homo sapiens (Human)2.0890718
P09874Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like ...PARP1142;Homo sapiens (Human)1.9986619
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)1.9606820
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)1.9513721
P17252Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCA5578;Homo sapiens (Human)1.9097222
P80370Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen ...DLK18788;Homo sapiens (Human)1.7934323
Q15910Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.43) (ENX-1) (Enhancer of zeste homolog ...Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, EZ subfamilyEZH22146;Homo sapiens (Human)1.7358424
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.7228825
Q13489Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) ...IAP familyBIRC3330;Homo sapiens (Human)1.7206526
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)1.666327
P98170E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein ...IAP familyXIAP331;Homo sapiens (Human)1.5902928
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.5774229
P00734Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide ...Peptidase S1 familyF22147;Homo sapiens (Human)1.5656730
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.5553731
P11309Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM15292;Homo sapiens (Human)1.5503732
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.4627233
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)1.4493134
P504065-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)G-protein coupled receptor 1 familyHTR63362;Homo sapiens (Human)1.3801935
P0DMS8Adenosine receptor A3G-protein coupled receptor 1 familyADORA3140;Homo sapiens (Human)1.3522836
P41143Delta-type opioid receptor (D-OR-1) (DOR-1)G-protein coupled receptor 1 familyOPRD14985;Homo sapiens (Human)1.2980937
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.2949338
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)1.2928239
P78527DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC ...PI3/PI4-kinase familyPRKDC5591;Homo sapiens (Human)1.2656540
Q9Y5Y9Sodium channel protein type 10 subunit alpha (Peripheral nerve sodium ...Sodium channel (TC 1.A.1.10) family, Nav1.8/SCN10A subfamilySCN10A6336;Homo sapiens (Human)1.2473141
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)1.2200142
P49286Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)G-protein coupled receptor 1 familyMTNR1B4544;Homo sapiens (Human)1.2104943
P29371Neuromedin-K receptor (NKR) (NK-3 receptor) (NK-3R) (Neurokinin B receptor) (Tachykinin ...G-protein coupled receptor 1 familyTACR36870;Homo sapiens (Human)1.2040544
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)1.186945
Q8NER1Transient receptor potential cation channel subfamily V member 1 (TrpV1) ...Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamilyTRPV17442;Homo sapiens (Human)1.1720146
P30291Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE17465;Homo sapiens (Human)1.1493147
Q136395-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4)G-protein coupled receptor 1 familyHTR43360;Homo sapiens (Human)1.135748
P11229Muscarinic acetylcholine receptor M1G-protein coupled receptor 1 family, Muscarinic acetylcholine receptor subfamily, CHRM1 ...CHRM11128;Homo sapiens (Human)1.0980249
Q96P09Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) ...IAP familyBIRC8112401;Homo sapiens (Human)1.0924750

[33] CHEMBL482967

Original SMILES:
Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1

Prepared SMILES:
Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C

P24864G1/S-specific cyclin-E1Cyclin family, Cyclin E subfamilyCCNE1898;Homo sapiens (Human)3.61092Known
P24385G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 ...Cyclin family, Cyclin D subfamilyCCND1595;Homo sapiens (Human)3.47566Known
O60563Cyclin-T1 (CycT1) (Cyclin-T)Cyclin family, Cyclin C subfamilyCCNT1904;Homo sapiens (Human)2.842521
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)2.76716Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)2.746012
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)2.62777Known
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)2.53577Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)2.51373Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)2.509393
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)2.5052Known
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)2.455994
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)2.43086Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)2.42557Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)2.408215
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)2.40115Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)2.388286
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)2.36476Known
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)2.36239Known
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)2.30521Known
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)2.29682Known
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)2.26331Known
O00311Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamilyCDC78317;Homo sapiens (Human)2.2561Known
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)2.225027
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)2.22145Known
P30291Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamilyWEE17465;Homo sapiens (Human)2.18982Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)2.13131Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)2.11885Known
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)2.104188
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.988129
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)1.98386Known
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.9731610
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)1.96742Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.92761Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)1.90301Known
P27448MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK34140;Homo sapiens (Human)1.88592Known
P14635G2/mitotic-specific cyclin-B1Cyclin family, Cyclin AB subfamilyCCNB1891;Homo sapiens (Human)1.8843411
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)1.80612
P30281G1/S-specific cyclin-D3Cyclin family, Cyclin D subfamilyCCND3896;Homo sapiens (Human)1.8047513
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)1.80245Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)1.79425Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.78111Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)1.77814Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)1.7723114
Q00535Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK51020;Homo sapiens (Human)1.7693Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)1.75376Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.7394Known
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)1.7278115
Q9Y463Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1B9149;Homo sapiens (Human)1.7199516
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.7064717
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)1.69897Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.68092Known
P31749RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT1207;Homo sapiens (Human)1.67914Known
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)1.675Known
Q15139Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD15587;Homo sapiens (Human)1.6692718
Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)1.6584519
P53350Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK15347;Homo sapiens (Human)1.6487720
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)1.62953Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)1.6258121
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)1.6052Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)1.59731Known
Q13627Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1A1859;Homo sapiens (Human)1.59677Known
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.59383Known
P20248Cyclin-A2 (Cyclin-A) (Cyclin A)Cyclin family, Cyclin AB subfamilyCCNA2890;Homo sapiens (Human)1.5816722
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.57911Known
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.57463Known
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)1.55562Known
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)1.5517523
Q13555Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2G818;Homo sapiens (Human)1.54189Known
P29274Adenosine receptor A2aG-protein coupled receptor 1 familyADORA2A135;Homo sapiens (Human)1.5384724
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)1.52845Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)1.5261525
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)1.5155926
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)1.50959Known
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)1.5093627
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)1.50495Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)1.5Known
Q13557Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2D817;Homo sapiens (Human)1.49986Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)1.4987228
Q8TDC3Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyBRSK184446;Homo sapiens (Human)1.49213Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)1.49163Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.49071Known
Q9Y243RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT310000;Homo sapiens (Human)1.4841629
Q8IW41MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMAPKAPK58550;Homo sapiens (Human)1.4824130
P49674Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1E102800317;1454;Homo sapiens (Human)1.4732631
P42336Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) ...PI3/PI4-kinase familyPIK3CA5290;Homo sapiens (Human)1.4728232
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.46944Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)1.46914Known
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.46907Known
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)1.4545633
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)1.4441734
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)1.43023Known
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)1.42863Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)1.4280535
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.425Known
P05067Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) ...APP familyAPP351;Homo sapiens (Human)1.4224436
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)1.42126Known
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)1.4096737
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)1.40906Known
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)1.4027438
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)1.37517Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)1.3730539
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)1.34626Known
Q00534Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK61021;Homo sapiens (Human)1.345740
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)1.344741
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.34191Known
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.33207Known
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)1.331442
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.3243143
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)1.3221744
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.3170545
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)1.31051Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)1.3095746
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)1.30385Known
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)1.3031947
P48730Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein ...Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1D1453;Homo sapiens (Human)1.29574Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)1.2924748
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)1.28643Known
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)1.2763549
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)1.27288Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)1.26413Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)1.2456650
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.23098Known
P51957Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK46787;Homo sapiens (Human)1.22397Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)1.22182Known
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)1.15Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)1.12943Known
Q9UEE5Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17A9263;Homo sapiens (Human)1.08224Known
P51955Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis ...Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamilyNEK24751;Homo sapiens (Human)1.05Known
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.025Known
P48729Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A11452;Homo sapiens (Human)0.9909Known
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)0.957287Known
Q9HBY8Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2)Protein kinase superfamily, AGC Ser/Thr protein kinase familySGK210110;Homo sapiens (Human)0.95Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)0.932292Known
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)0.876601Known
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)0.853389Known
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)0.83991Known
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2A815;Homo sapiens (Human)0.834819Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)0.791809Known
Q9HCP0Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G153944;Homo sapiens (Human)0.775515Known
P78368Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G21455;Homo sapiens (Human)0.774999Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)0.733193Known
P53778Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK126300;Homo sapiens (Human)0.70672Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)0.697003Known
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)0.692024Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)0.675Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)0.48072Known
Q13554Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2B816;Homo sapiens (Human)0.441873Known

[34] CHEMBL1991078

Original SMILES:
COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC

Prepared SMILES:
COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1

P83916Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) ...CBX110951;Homo sapiens (Human)3.221851
P49286Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)G-protein coupled receptor 1 familyMTNR1B4544;Homo sapiens (Human)3.098032
Q92731Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A ...Nuclear hormone receptor family, NR3 subfamilyESR22100;Homo sapiens (Human)2.799723
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)2.798534
Q13255Metabotropic glutamate receptor 1 (mGluR1)G-protein coupled receptor 3 familyGRM12911;Homo sapiens (Human)2.520555
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)2.488116
P03372Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 ...Nuclear hormone receptor family, NR3 subfamilyESR12099;Homo sapiens (Human)2.394397
Q9BV23Monoacylglycerol lipase ABHD6 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein ...AB hydrolase superfamilyABHD657406;Homo sapiens (Human)2.334478
P282225-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (S12) (Serotonin 1D beta receptor) ...G-protein coupled receptor 1 familyHTR1B3351;Homo sapiens (Human)2.196199
Q8NER1Transient receptor potential cation channel subfamily V member 1 (TrpV1) ...Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamilyTRPV17442;Homo sapiens (Human)2.1959410
Q8NCG7Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-) (KCCR13L)AB hydrolase superfamily, Lipase familyDAGLB221955;Homo sapiens (Human)2.1100411
P00742Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved ...Peptidase S1 familyF102159;Homo sapiens (Human)2.1091712
P282215-hydroxytryptamine receptor 1D (5-HT-1D) (5-HT1D) (Serotonin 1D alpha receptor) (5-HT-1D-alpha) ...G-protein coupled receptor 1 familyHTR1D3352;Homo sapiens (Human)2.0800413
P089085-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamilyHTR1A3350;Homo sapiens (Human)2.04714
P15538Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid ...Cytochrome P450 familyCYP11B11584;Homo sapiens (Human)1.9650915
P34972Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)G-protein coupled receptor 1 familyCNR21269;Homo sapiens (Human)1.954616
P05067Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) ...APP familyAPP351;Homo sapiens (Human)1.9160117
P03952Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) (PKK) ...Peptidase S1 family, Plasma kallikrein subfamilyKLKB13818;Homo sapiens (Human)1.88318
P09874Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like ...PARP1142;Homo sapiens (Human)1.863119
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)1.8176120
P41594Metabotropic glutamate receptor 5 (mGluR5)G-protein coupled receptor 3 familyGRM52915;Homo sapiens (Human)1.8117221
P35462D(3) dopamine receptor (Dopamine D3 receptor)G-protein coupled receptor 1 familyDRD31814;Homo sapiens (Human)1.8101222
P27338Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) ...Flavin monoamine oxidase familyMAOB4129;Homo sapiens (Human)1.7818423
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.6845624
P09917Arachidonate 5-lipoxygenase (5-LO) (5-lipoxygenase) (EC 1.13.11.34)Lipoxygenase familyALOX5240;Homo sapiens (Human)1.6761625
P11511Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen ...Cytochrome P450 familyCYP19A11588;Homo sapiens (Human)1.6624226
Q9Y4D2Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived ...AB hydrolase superfamily, Lipase familyDAGLA747;Homo sapiens (Human)1.6379827
P35372Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid ...G-protein coupled receptor 1 familyOPRM14988;Homo sapiens (Human)1.633628
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.6201929
Q99705Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein ...G-protein coupled receptor 1 familyMCHR12847;Homo sapiens (Human)1.6101130
P30542Adenosine receptor A1G-protein coupled receptor 1 familyADORA1134;Homo sapiens (Human)1.6091231
P14061Estradiol 17-beta-dehydrogenase 1 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 1) (17-beta-HSD ...Short-chain dehydrogenases/reductases (SDR) familyHSD17B13292;Homo sapiens (Human)1.5968332
P00918Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA2760;Homo sapiens (Human)1.5645533
P0DMS8Adenosine receptor A3G-protein coupled receptor 1 familyADORA3140;Homo sapiens (Human)1.5621434
P48039Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)G-protein coupled receptor 1 familyMTNR1A4543;Homo sapiens (Human)1.537435
P27815cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.53) (DPDE2) (PDE46)Cyclic nucleotide phosphodiesterase family, PDE4 subfamilyPDE4A5141;Homo sapiens (Human)1.5097236
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.4701337
Q13547Histone deacetylase 1 (HD1) (EC 3.5.1.98)Histone deacetylase family, HD type 1 subfamilyHDAC13065;Homo sapiens (Human)1.4618938
O43570Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA12771;Homo sapiens (Human)1.3338439
P25101Endothelin-1 receptor (Endothelin receptor type A) (ET-A) (ETA-R) (hET-AR)G-protein coupled receptor 1 family, Endothelin receptor subfamily, EDNRA sub-subfamilyEDNRA1909;Homo sapiens (Human)1.3329240
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)1.3267141
P78527DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC ...PI3/PI4-kinase familyPRKDC5591;Homo sapiens (Human)1.324942
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)1.3041843
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)1.3012444
P00915Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA1759;Homo sapiens (Human)1.2902845
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)1.2651746
P35348Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) ...G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1A sub-subfamilyADRA1A148;Homo sapiens (Human)1.2620947
P504065-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)G-protein coupled receptor 1 familyHTR63362;Homo sapiens (Human)1.238448
P29274Adenosine receptor A2aG-protein coupled receptor 1 familyADORA2A135;Homo sapiens (Human)1.2311749
Q96RI0Proteinase-activated receptor 4 (PAR-4) (Coagulation factor II receptor-like 3) (Thrombin ...G-protein coupled receptor 1 familyF2RL39002;Homo sapiens (Human)1.2293950

[35] CHEMBL244378

Original SMILES:
O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1

Prepared SMILES:
OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2

P00374Dihydrofolate reductase (EC 1.5.1.3)Dihydrofolate reductase familyDHFR1719;Homo sapiens (Human)3.42751
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)2.923052
Q6UVM3Potassium channel subfamily T member 2 (Sequence like an intermediate ...Potassium channel family, Calcium-activated (TC 1.A.1.3) subfamily, KCa4.2/KCNT2 sub-subfamilyKCNT2343450;Homo sapiens (Human)2.734443
Q8NER1Transient receptor potential cation channel subfamily V member 1 (TrpV1) ...Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamilyTRPV17442;Homo sapiens (Human)2.379924
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)2.351455
Q16602Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) ...G-protein coupled receptor 2 familyCALCRL10203;Homo sapiens (Human)2.317316
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)2.288147
P12104Fatty acid-binding protein, intestinal (Fatty acid-binding protein 2) (Intestinal-type fatty ...Calycin superfamily, Fatty-acid binding protein (FABP) familyFABP22169;Homo sapiens (Human)2.278818
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)2.238119
O43570Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA12771;Homo sapiens (Human)2.2226310
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.9872311
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)1.8431912
P09917Arachidonate 5-lipoxygenase (5-LO) (5-lipoxygenase) (EC 1.13.11.34)Lipoxygenase familyALOX5240;Homo sapiens (Human)1.8072813
P27338Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) ...Flavin monoamine oxidase familyMAOB4129;Homo sapiens (Human)1.7402314
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)1.7262515
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.7001716
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)1.6830317
P11137Microtubule-associated protein 2 (MAP-2)MAP24133;Homo sapiens (Human)1.6602618
P42330Aldo-keto reductase family 1 member C3 (EC 1.-.-.-) (17-beta-hydroxysteroid dehydrogenase ...Aldo/keto reductase familyAKR1C38644;Homo sapiens (Human)1.6555219
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)1.6430920
Q14833Metabotropic glutamate receptor 4 (mGluR4)G-protein coupled receptor 3 familyGRM42914;Homo sapiens (Human)1.5974921
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)1.512722
Q9H244P2Y purinoceptor 12 (P2Y12) (ADP-glucose receptor) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) ...G-protein coupled receptor 1 familyP2RY1264805;Homo sapiens (Human)1.4940923
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)1.4514824
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.4358925
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)1.4239626
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.4113427
P312133-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.1.22) (5 alpha-SR2) (SR type 2) ...Steroid 5-alpha reductase familySRD5A26716;Homo sapiens (Human)1.406828
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.3717829
Q15722Leukotriene B4 receptor 1 (LTB4-R 1) (LTB4-R1) (Chemoattractant receptor-like 1) ...G-protein coupled receptor 1 familyLTB4R1241;Homo sapiens (Human)1.3643330
P68400Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A11457;Homo sapiens (Human)1.3629531
P00915Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA1759;Homo sapiens (Human)1.36132
P50579Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Initiation ...Peptidase M24A family, Methionine aminopeptidase eukaryotic type 2 subfamilyMETAP210988;Homo sapiens (Human)1.3382733
P00918Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA2760;Homo sapiens (Human)1.3353334
Q04828Aldo-keto reductase family 1 member C1 (EC 1.1.1.-) (20-alpha-hydroxysteroid dehydrogenase) ...Aldo/keto reductase familyAKR1C11645;Homo sapiens (Human)1.3204735
P13631Retinoic acid receptor gamma (RAR-gamma) (Nuclear receptor subfamily 1 group ...Nuclear hormone receptor family, NR1 subfamilyRARG5916;Homo sapiens (Human)1.2906836
P10826Retinoic acid receptor beta (RAR-beta) (HBV-activated protein) (Nuclear receptor subfamily ...Nuclear hormone receptor family, NR1 subfamilyRARB5915;Homo sapiens (Human)1.275437
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)1.2305238
Q04609Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Cell growth-inhibiting gene 27 protein) ...Peptidase M28 family, M28B subfamilyFOLH12346;Homo sapiens (Human)1.2237839
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.198240
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.1975741
P30556Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) ...G-protein coupled receptor 1 familyAGTR1185;Homo sapiens (Human)1.1823642
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.1716343
P31645Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family ...Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamilySLC6A46532;Homo sapiens (Human)1.1667244
Q16790Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA9768;Homo sapiens (Human)1.1661445
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)1.1545846
P11511Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen ...Cytochrome P450 familyCYP19A11588;Homo sapiens (Human)1.1252347
P12268Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2) (IMPD 2) (IMPDH 2) ...IMPDH/GMPR familyIMPDH23615;Homo sapiens (Human)1.1222148
P41594Metabotropic glutamate receptor 5 (mGluR5)G-protein coupled receptor 3 familyGRM52915;Homo sapiens (Human)1.1090849
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)1.0974650

[36] CHEMBL1967878

Original SMILES:
Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1

Prepared SMILES:
CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F

P35462D(3) dopamine receptor (Dopamine D3 receptor)G-protein coupled receptor 1 familyDRD31814;Homo sapiens (Human)3.839461
P504065-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)G-protein coupled receptor 1 familyHTR63362;Homo sapiens (Human)3.700552
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)3.470843
P00374Dihydrofolate reductase (EC 1.5.1.3)Dihydrofolate reductase familyDHFR1719;Homo sapiens (Human)3.194144
P089085-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamilyHTR1A3350;Homo sapiens (Human)2.993555
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)2.8926
P34913Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) ...AB hydrolase superfamily, Epoxide hydrolase familyEPHX22053;Homo sapiens (Human)2.831587
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)2.79838
P43115Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 ...G-protein coupled receptor 1 familyPTGER35733;Homo sapiens (Human)2.643519
P35367Histamine H1 receptor (H1R) (HH1R)G-protein coupled receptor 1 familyHRH13269;Homo sapiens (Human)2.6022610
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)2.5846311
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)2.5800112
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)2.5192313
P41145Kappa-type opioid receptor (K-OR-1) (KOR-1)G-protein coupled receptor 1 familyOPRK14986;Homo sapiens (Human)2.5025414
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)2.4820315
P415955-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)G-protein coupled receptor 1 familyHTR2B3357;Homo sapiens (Human)2.2919116
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)2.1836917
P21917D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)G-protein coupled receptor 1 familyDRD41815;Homo sapiens (Human)2.1298818
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)2.0839619
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)2.040820
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)1.9975221
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)1.9862122
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.9658823
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.9558524
P283355-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) ...G-protein coupled receptor 1 familyHTR2C3358;Homo sapiens (Human)1.9127525
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)1.8954526
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)1.8347427
P25100Alpha-1D adrenergic receptor (Alpha-1A adrenergic receptor) (Alpha-1D adrenoreceptor) (Alpha-1D adrenoceptor) ...G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1D sub-subfamilyADRA1D146;Homo sapiens (Human)1.8205428
P10275Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C ...Nuclear hormone receptor family, NR3 subfamilyAR367;Homo sapiens (Human)1.8184329
Q8N884Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (2'3'-cGAMP ...Mab-21 familyCGAS115004;Homo sapiens (Human)1.792230
Q99705Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein ...G-protein coupled receptor 1 familyMCHR12847;Homo sapiens (Human)1.7855331
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)1.7201732
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.706733
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)1.6951534
P34981Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberin receptor)G-protein coupled receptor 1 familyTRHR7201;Homo sapiens (Human)1.6488235
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.6444936
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)1.6017737
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)1.5973538
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)1.5933139
O43570Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA12771;Homo sapiens (Human)1.5800940
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)1.5496341
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)1.5492742
P29274Adenosine receptor A2aG-protein coupled receptor 1 familyADORA2A135;Homo sapiens (Human)1.5176243
P282215-hydroxytryptamine receptor 1D (5-HT-1D) (5-HT1D) (Serotonin 1D alpha receptor) (5-HT-1D-alpha) ...G-protein coupled receptor 1 familyHTR1D3352;Homo sapiens (Human)1.4957744
P14324Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate ...FPP/GGPP synthase familyFDPS2224;Homo sapiens (Human)1.4919745
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)1.4868146
Q13547Histone deacetylase 1 (HD1) (EC 3.5.1.98)Histone deacetylase family, HD type 1 subfamilyHDAC13065;Homo sapiens (Human)1.4743647
Q99720Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding ...ERG2 familySIGMAR110280;Homo sapiens (Human)1.4592448
P27487Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein ...Peptidase S9B family, DPPIV subfamilyDPP41803;Homo sapiens (Human)1.459249
P35408Prostaglandin E2 receptor EP4 subtype (PGE receptor EP4 subtype) (PGE2 ...G-protein coupled receptor 1 familyPTGER45734;Homo sapiens (Human)1.4464150

[37] CHEMBL1241473

Original SMILES:
COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC

Prepared SMILES:
COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC

P05067Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) ...APP familyAPP351;Homo sapiens (Human)2.729541
Q8TDV5Glucose-dependent insulinotropic receptor (G-protein coupled receptor 119)G-protein coupled receptor 1 familyGPR119139760;Homo sapiens (Human)2.66412
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)2.40613
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)2.375274
O43570Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA12771;Homo sapiens (Human)2.340595
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)2.333686
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)2.304647
P35372Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid ...G-protein coupled receptor 1 familyOPRM14988;Homo sapiens (Human)2.297788
P27815cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.53) (DPDE2) (PDE46)Cyclic nucleotide phosphodiesterase family, PDE4 subfamilyPDE4A5141;Homo sapiens (Human)2.288789
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)2.2396310
Q13936Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, ...Calcium channel alpha-1 subunit (TC 1.A.1.11) family, CACNA1C subfamilyCACNA1C775;Homo sapiens (Human)2.1803211
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)2.1417612
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)2.049413
Q16790Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA9768;Homo sapiens (Human)2.0311714
P35462D(3) dopamine receptor (Dopamine D3 receptor)G-protein coupled receptor 1 familyDRD31814;Homo sapiens (Human)1.9118715
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.8711816
P21964Catechol O-methyltransferase (EC 2.1.1.6)Class I-like SAM-binding methyltransferase superfamily, Cation-dependent O-methyltransferase familyCOMT1312;Homo sapiens (Human)1.8709617
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)1.8601718
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)1.8506819
P49286Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)G-protein coupled receptor 1 familyMTNR1B4544;Homo sapiens (Human)1.838820
P21917D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)G-protein coupled receptor 1 familyDRD41815;Homo sapiens (Human)1.8321521
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.7965422
P00374Dihydrofolate reductase (EC 1.5.1.3)Dihydrofolate reductase familyDHFR1719;Homo sapiens (Human)1.7923723
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)1.7865724
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)1.7692525
P10275Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C ...Nuclear hormone receptor family, NR3 subfamilyAR367;Homo sapiens (Human)1.7229926
P504065-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)G-protein coupled receptor 1 familyHTR63362;Homo sapiens (Human)1.6300427
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)1.6274428
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.6271429
P10145Interleukin-8 (IL-8) (C-X-C motif chemokine 8) (Chemokine (C-X-C motif) ligand ...Intercrine alpha (chemokine CxC) familyCXCL83576;Homo sapiens (Human)1.6246330
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)1.615631
Q136395-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4)G-protein coupled receptor 1 familyHTR43360;Homo sapiens (Human)1.5996932
P089085-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamilyHTR1A3350;Homo sapiens (Human)1.5965533
P41145Kappa-type opioid receptor (K-OR-1) (KOR-1)G-protein coupled receptor 1 familyOPRK14986;Homo sapiens (Human)1.5853934
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)1.5441935
Q99808Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative ...SLC29A/ENT transporter (TC 2.A.57) familySLC29A12030;Homo sapiens (Human)1.5410836
P41143Delta-type opioid receptor (D-OR-1) (DOR-1)G-protein coupled receptor 1 familyOPRD14985;Homo sapiens (Human)1.5341437
P460985-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) ...Ligand-gated ion channel (TC 1.A.9) family, 5-hydroxytryptamine receptor (TC 1.A.9.2) ...HTR3A3359;Homo sapiens (Human)1.524138
P415955-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)G-protein coupled receptor 1 familyHTR2B3357;Homo sapiens (Human)1.5083539
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)1.5032440
P51679C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) ...G-protein coupled receptor 1 familyCCR41233;Homo sapiens (Human)1.4968341
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.4791942
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)1.4711443
Q07343cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.53) (DPDE4) (PDE32)Cyclic nucleotide phosphodiesterase family, PDE4 subfamilyPDE4B5142;Homo sapiens (Human)1.4471544
P09874Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like ...PARP1142;Homo sapiens (Human)1.4191245
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)1.4016246
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.3929247
P41594Metabotropic glutamate receptor 5 (mGluR5)G-protein coupled receptor 3 familyGRM52915;Homo sapiens (Human)1.3906648
P83916Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) ...CBX110951;Homo sapiens (Human)1.3680649
P15538Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid ...Cytochrome P450 familyCYP11B11584;Homo sapiens (Human)1.348650

[38] CHEMBL1973540

Original SMILES:
O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1

Prepared SMILES:
O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2

P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)2.930021
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)2.92522
P05067Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) ...APP familyAPP351;Homo sapiens (Human)2.887593
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)2.850874
P43166Carbonic anhydrase 7 (EC 4.2.1.1) (Carbonate dehydratase VII) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA7766;Homo sapiens (Human)2.747365
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)2.743516
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)2.681347
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)2.568078
Q16790Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA9768;Homo sapiens (Human)2.393969
O43570Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA12771;Homo sapiens (Human)2.3564510
P35218Carbonic anhydrase 5A, mitochondrial (EC 4.2.1.1) (Carbonate dehydratase VA) (Carbonic ...Alpha-carbonic anhydrase familyCA5A763;Homo sapiens (Human)2.3193511
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)2.3025312
Q9Y2D0Carbonic anhydrase 5B, mitochondrial (EC 4.2.1.1) (Carbonate dehydratase VB) (Carbonic ...Alpha-carbonic anhydrase familyCA5B11238;Homo sapiens (Human)2.2888713
Q8NER1Transient receptor potential cation channel subfamily V member 1 (TrpV1) ...Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamilyTRPV17442;Homo sapiens (Human)2.2310614
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)2.153715
P25101Endothelin-1 receptor (Endothelin receptor type A) (ET-A) (ETA-R) (hET-AR)G-protein coupled receptor 1 family, Endothelin receptor subfamily, EDNRA sub-subfamilyEDNRA1909;Homo sapiens (Human)2.1120916
P22303Acetylcholinesterase (AChE) (EC 3.1.1.7)Type-B carboxylesterase/lipase familyACHE43;Homo sapiens (Human)1.9746417
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.8753618
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)1.8467519
P49286Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)G-protein coupled receptor 1 familyMTNR1B4544;Homo sapiens (Human)1.7605820
Q9H237Protein-serine O-palmitoleoyltransferase porcupine (EC 2.3.1.250) (Protein MG61)Membrane-bound acyltransferase family, Porcupine subfamilyPORCN64840;Homo sapiens (Human)1.7475821
P00742Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved ...Peptidase S1 familyF102159;Homo sapiens (Human)1.7464622
P50579Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Initiation ...Peptidase M24A family, Methionine aminopeptidase eukaryotic type 2 subfamilyMETAP210988;Homo sapiens (Human)1.7277823
P34972Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)G-protein coupled receptor 1 familyCNR21269;Homo sapiens (Human)1.7240524
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)1.7170925
P504065-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)G-protein coupled receptor 1 familyHTR63362;Homo sapiens (Human)1.7016826
P34913Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) ...AB hydrolase superfamily, Epoxide hydrolase familyEPHX22053;Homo sapiens (Human)1.6960127
Q9ULX7Carbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA1423632;Homo sapiens (Human)1.6801528
P00915Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA1759;Homo sapiens (Human)1.6628529
Q13547Histone deacetylase 1 (HD1) (EC 3.5.1.98)Histone deacetylase family, HD type 1 subfamilyHDAC13065;Homo sapiens (Human)1.6051830
P51679C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) ...G-protein coupled receptor 1 familyCCR41233;Homo sapiens (Human)1.563331
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)1.5002832
P03372Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 ...Nuclear hormone receptor family, NR3 subfamilyESR12099;Homo sapiens (Human)1.4784333
Q15761Neuropeptide Y receptor type 5 (NPY5-R) (NPY-Y5 receptor) (NPYY5-R) (Y5 ...G-protein coupled receptor 1 familyNPY5R4889;Homo sapiens (Human)1.4729234
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.4431935
P48039Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)G-protein coupled receptor 1 familyMTNR1A4543;Homo sapiens (Human)1.4365936
O15552Free fatty acid receptor 2 (G-protein coupled receptor 43)G-protein coupled receptor 1 familyFFAR22867;Homo sapiens (Human)1.4198237
P09960Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)Peptidase M1 familyLTA4H4048;Homo sapiens (Human)1.4145838
P283355-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) ...G-protein coupled receptor 1 familyHTR2C3358;Homo sapiens (Human)1.3952339
P15538Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid ...Cytochrome P450 familyCYP11B11584;Homo sapiens (Human)1.3748840
Q02127Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase)Dihydroorotate dehydrogenase family, Type 2 subfamilyDHODH1723;Homo sapiens (Human)1.318141
P00918Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA2760;Homo sapiens (Human)1.2865842
P11511Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen ...Cytochrome P450 familyCYP19A11588;Homo sapiens (Human)1.2615443
P42336Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) ...PI3/PI4-kinase familyPIK3CA5290;Homo sapiens (Human)1.2425344
P48736Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) ...PI3/PI4-kinase familyPIK3CG5294;Homo sapiens (Human)1.2039445
P19525Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK25610;Homo sapiens (Human)1.2006846
O00329Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) ...PI3/PI4-kinase familyPIK3CD5293;Homo sapiens (Human)1.1724747
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)1.1606348
P29274Adenosine receptor A2aG-protein coupled receptor 1 familyADORA2A135;Homo sapiens (Human)1.1600349
P16083Ribosyldihydronicotinamide dehydrogenase [quinone] (EC 1.10.5.1) (NRH dehydrogenase [quinone] 2) (NRH:quinone ...NAD(P)H dehydrogenase (quinone) familyNQO24835;Homo sapiens (Human)1.1243650

[39] CHEMBL428690

Original SMILES:
CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1

Prepared SMILES:
CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O

P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)3.448971
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)3.401262
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)3.144013
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)2.8709Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)2.762694
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)2.755365
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)2.65866
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)2.636767
P24723Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCH5583;Homo sapiens (Human)2.62696Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)2.62316Known
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)2.46228
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)2.44486Known
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)2.443859
P05771Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCB5579;Homo sapiens (Human)2.433710
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)2.42941Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)2.40889Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)2.3493211
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)2.33589Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)2.3280412
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)2.3252613
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)2.3022214
P17252Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCA5578;Homo sapiens (Human)2.27346Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)2.203Known
Q9BWU1Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1923097;Homo sapiens (Human)2.17498Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)2.17176Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)2.1404815
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)2.0863116
Q02156Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCE5581;Homo sapiens (Human)2.07294Known
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)2.07266Known
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)2.0507517
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)2.0138218
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)2.00914Known
Q8TD08Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK15225689;Homo sapiens (Human)1.94333Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)1.9405919
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)1.9362820
O76039Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL56792;Homo sapiens (Human)1.92241Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)1.9162121
P14616Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSRR3645;Homo sapiens (Human)1.9160122
O00311Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamilyCDC78317;Homo sapiens (Human)1.9130623
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)1.9053Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.8992124
Q00526Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK31018;Homo sapiens (Human)1.88491Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)1.88405Known
Q00535Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK51020;Homo sapiens (Human)1.86706Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)1.8609225
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)1.83659Known
Q9Y463Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1B9149;Homo sapiens (Human)1.82494Known
Q13627Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1A1859;Homo sapiens (Human)1.80206Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)1.79836Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)1.7932226
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.79068Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)1.78497Known
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)1.78438Known
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.7803Known
P06493Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1983;Homo sapiens (Human)1.7611Known
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)1.7601527
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.7571428
P29322Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA82046;Homo sapiens (Human)1.7522929
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)1.6836530
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.6697731
Q92731Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A ...Nuclear hormone receptor family, NR3 subfamilyESR22100;Homo sapiens (Human)1.6643832
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.6641233
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)1.639434
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)1.63541Known
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.62184Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)1.6210635
P54764Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA42043;Homo sapiens (Human)1.6181736
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)1.6116937
Q9UQ88Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK11A728642;Homo sapiens (Human)1.6095338
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)1.60578Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)1.6015739
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)1.596140
P20794Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyMAK4117;Homo sapiens (Human)1.59035Known
Q59H18Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase ...TNNI3K100526835;51086;Homo sapiens (Human)1.58542Known
Q00537Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK175128;Homo sapiens (Human)1.58524Known
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)1.5752141
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)1.56965Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)1.567Known
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)1.5613242
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)1.5551243
P29323Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB22048;Homo sapiens (Human)1.5488944
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.54627Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.54439Known
O94921Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK145218;Homo sapiens (Human)1.53626Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.523745
Q04759Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCQ5588;Homo sapiens (Human)1.51451Known
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)1.5058246
P48730Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein ...Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1D1453;Homo sapiens (Human)1.5049447
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)1.504Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)1.5037848
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.5015649
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.49652Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)1.48864Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)1.48608Known
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)1.4856250
Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)1.46676Known
P37023Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVRL194;Homo sapiens (Human)1.45988Known
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)1.45687Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)1.44941Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)1.43095Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)1.40964Known
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)1.38658Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)1.38494Known
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)1.36614Known
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.34194Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)1.34174Known
P54756Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA52044;Homo sapiens (Human)1.33203Known
P37173TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR27048;Homo sapiens (Human)1.32932Known
P11309Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM15292;Homo sapiens (Human)1.30925Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)1.29224Known
Q13705Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2B93;Homo sapiens (Human)1.27978Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.26162Known
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)1.25825Known
Q15139Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD15587;Homo sapiens (Human)1.25598Known
Q09013Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyDMPK1760;Homo sapiens (Human)1.25248Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)1.23134Known
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.22397Known
Q9HCP0Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1G153944;Homo sapiens (Human)1.21986Known
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.20764Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)1.19239Known
Q00534Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK61021;Homo sapiens (Human)1.19152Known
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.18274Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)1.1806Known
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.1669Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)1.15663Known
Q9C098Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK385443;Homo sapiens (Human)1.15442Known
Q07002Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK185129;Homo sapiens (Human)1.14875Known
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)1.13965Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)1.12813Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)1.12565Known
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)1.12109Known
P11217Glycogen phosphorylase, muscle form (EC 2.4.1.1) (Myophosphorylase)Glycogen phosphorylase familyPYGM5837;Homo sapiens (Human)1.1156Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)1.10539Known
Q13164Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK75598;Homo sapiens (Human)1.10411Known
O15075Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK19201;Homo sapiens (Human)1.07972Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.06467Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)1.06012Known
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)1.05692Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)1.04976Known
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)1.03269Known
Q16566Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK4814;Homo sapiens (Human)1.02006Known
P49761Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK31198;Homo sapiens (Human)1.01955Known
P48729Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A11452;Homo sapiens (Human)1.01537Known
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.00275Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)1.00228Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)0.997106Known
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)0.995114Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)0.992333Known
O14578Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)Protein kinase superfamily, AGC Ser/Thr protein kinase familyCIT11113;Homo sapiens (Human)0.990947Known
Q8WTQ7Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK7131890;Homo sapiens (Human)0.982997Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)0.980394Known
Q9BQI3Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK127102;Homo sapiens (Human)0.97224Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)0.968416Known
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)0.945171Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)0.935157Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)0.925122Known
Q15835Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK16011;Homo sapiens (Human)0.923784Known
Q8TBX8Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2C79837;Homo sapiens (Human)0.92297Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)0.881318Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)0.880219Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)0.868158Known
Q86Y07Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, VRK subfamilyVRK27444;Homo sapiens (Human)0.866115Known
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)0.862066Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)0.853253Known
Q13557Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2D817;Homo sapiens (Human)0.84897Known
Q9UEE5Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17A9263;Homo sapiens (Human)0.841976Known
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)0.835479Known
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)0.825509Known
Q9HBH9MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMKNK22872;Homo sapiens (Human)0.824605Known
Q96Q40Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1565061;Homo sapiens (Human)0.816239Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)0.808688Known
Q16816Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG15260;Homo sapiens (Human)0.808362Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)0.8008Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)0.773256Known
P19525Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK25610;Homo sapiens (Human)0.756579Known
P27037Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2A92;Homo sapiens (Human)0.747273Known
Q05655Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCD5580;Homo sapiens (Human)0.731258Known
Q9UQM7Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2A815;Homo sapiens (Human)0.718648Known
O60331Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC ...PIP5K1C23396;Homo sapiens (Human)0.711626Known
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)0.678575Known
Q6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein ...Protein kinase superfamily, Ser/Thr protein kinase familyDSTYK25778;Homo sapiens (Human)0.671595Known
Q13555Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2G818;Homo sapiens (Human)0.657181Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)0.646893Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)0.631655Known
Q8N752Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1A1L122011;Homo sapiens (Human)0.628546Known
P45985Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K46416;Homo sapiens (Human)0.61387Known
O94768Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17B9262;Homo sapiens (Human)0.589392Known
Q9Y5S2Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPB9578;Homo sapiens (Human)0.581872Known
Q13554Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK2B816;Homo sapiens (Human)0.569836Known
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)0.438968Known
Q8WU08Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySTK32A202374;Homo sapiens (Human)0.437893Known
Q02779Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K104294;Homo sapiens (Human)0.433666Known
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)0.426606Known
Q16512Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN15585;Homo sapiens (Human)0.368708Known
Q9NUW8Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-)Tyrosyl-DNA phosphodiesterase familyTDP155775;Homo sapiens (Human)0.326088Known
Q5VT25Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPA8476;Homo sapiens (Human)0.232471Known

[40] CHEMBL1908395

Original SMILES:
CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl

Prepared SMILES:
N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C

P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)2.96817Known
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)2.85887Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)2.85772Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)2.80611Known
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)2.78431Known
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)2.78236Known
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)2.55728Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)2.55245Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)2.47589Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)2.42845Known
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)2.42331Known
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)2.37992Known
P546465'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA25563;Homo sapiens (Human)2.36506Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)2.33978Known
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)2.33632Known
P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)2.32319Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)2.291811
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)2.29103Known
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)2.25246Known
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)2.24342Known
Q05655Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCD5580;Homo sapiens (Human)2.234522
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)2.202813
O14757Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamilyCHEK11111;Homo sapiens (Human)2.18397Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)2.17006Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)2.15183Known
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)2.13824Known
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)2.065554
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)2.06327Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)2.04878Known
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)2.02594Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)2.02191Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)2.01467Known
P50613Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK71022;Homo sapiens (Human)1.986785
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.975976
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)1.96782Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)1.96534Known
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)1.96259Known
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)1.91495Known
Q16539Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK141432;Homo sapiens (Human)1.888757
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)1.87663Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)1.87271Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)1.8648
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.86047Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)1.85804Known
P49840Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3A2931;Homo sapiens (Human)1.84203Known
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)1.83914Known
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.8251Known
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)1.81686Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.80134Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)1.78586Known
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.77112Known
Q14680Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMELK9833;Homo sapiens (Human)1.74896Known
Q131315'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyPRKAA15562;Homo sapiens (Human)1.74177Known
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.72884Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.703979
Q9H3Y6Tyrosine-protein kinase Srms (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRMS6725;Homo sapiens (Human)1.6888510
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.68843Known
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)1.68467Known
P17612cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamilyPRKACA5566;Homo sapiens (Human)1.6845211
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)1.68331Known
Q9BWU1Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1923097;Homo sapiens (Human)1.681712
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)1.67253Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)1.66463Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)1.65284Known
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)1.6471913
P36896Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR1B91;Homo sapiens (Human)1.63276Known
O14920Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKB3551;Homo sapiens (Human)1.6267514
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)1.62398Known
P53350Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK15347;Homo sapiens (Human)1.618815
Q04759Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCQ5588;Homo sapiens (Human)1.6142516
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)1.6077417
Q15375Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA72045;Homo sapiens (Human)1.60589Known
P53667LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLIMK13984;Homo sapiens (Human)1.6031118
O75582Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA59252;Homo sapiens (Human)1.5966619
Q96SB4SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK16732;Homo sapiens (Human)1.58953Known
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.58887Known
P05129Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCG5582;Homo sapiens (Human)1.5861520
Q99755Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC ...PIP5K1A8394;Homo sapiens (Human)1.58024Known
Q14004Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK138621;Homo sapiens (Human)1.5779621
Q9NWT8Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, ...Mitochondrion-specific ribosomal protein mS38 familyAURKAIP154998;Homo sapiens (Human)1.5747622
P50750Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK91025;Homo sapiens (Human)1.5718223
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)1.57093Known
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)1.56588Known
Q14289Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK2B2185;Homo sapiens (Human)1.56485Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)1.56009Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)1.53539Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)1.53475Known
Q9Y2K2Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK323387;Homo sapiens (Human)1.53324
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.52047Known
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)1.5173225
Q86Z02Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK1204851;Homo sapiens (Human)1.5158226
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)1.51315Known
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)1.50842Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)1.50796Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)1.50321Known
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)1.4977Known
Q9UL54Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK29344;Homo sapiens (Human)1.4887327
P23443Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KB16198;Homo sapiens (Human)1.4793328
P06241Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFYN2534;Homo sapiens (Human)1.47681Known
P31645Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family ...Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamilySLC6A46532;Homo sapiens (Human)1.4654929
O96017Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamilyCHEK211200;Homo sapiens (Human)1.4601830
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.4581431
Q13976cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG15592;Homo sapiens (Human)1.4374632
Q02156Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCE5581;Homo sapiens (Human)1.4369333
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.4338534
O43283Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K139175;Homo sapiens (Human)1.42607Known
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.42096Known
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)1.42086Known
Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK18737;Homo sapiens (Human)1.42082Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)1.40565Known
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.3937235
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)1.38982Known
Q13237cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamilyPRKG25593;Homo sapiens (Human)1.3825236
O75914Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK35063;Homo sapiens (Human)1.375Known
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)1.3743337
Q9UEE5Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17A9263;Homo sapiens (Human)1.37346Known
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)1.37323Known
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)1.36941Known
Q13873Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR2659;Homo sapiens (Human)1.36917Known
P11309Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM15292;Homo sapiens (Human)1.36591Known
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)1.36536Known
Q9BVS4Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK255781;Homo sapiens (Human)1.345138
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)1.3378939
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)1.33763Known
P17252Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCA5578;Homo sapiens (Human)1.3365240
Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)1.32958Known
P04049RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyRAF15894;Homo sapiens (Human)1.3275241
Q8WTQ7Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK7131890;Homo sapiens (Human)1.32697Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)1.322942
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)1.3172743
Q9UPZ9Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyICK22858;Homo sapiens (Human)1.3134344
O14730Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK38780;Homo sapiens (Human)1.31264Known
Q9BRS2Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK183732;Homo sapiens (Human)1.31068Known
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)1.30718Known
O94806Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD323683;Homo sapiens (Human)1.30464Known
Q13627Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1A1859;Homo sapiens (Human)1.304645
P49674Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase ...CSNK1E102800317;1454;Homo sapiens (Human)1.2994346
P05771Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCB5579;Homo sapiens (Human)1.2916147
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)1.28452Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)1.2843Known
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)1.2764548
P41240Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyCSK1445;Homo sapiens (Human)1.2757149
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.2597Known
Q16816Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG15260;Homo sapiens (Human)1.25835Known
P57078Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK4Homo sapiens (Human)1.2559950
P14616Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSRR3645;Homo sapiens (Human)1.24384Known
P78362SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK26733;Homo sapiens (Human)1.24245Known
Q9H0K1Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilySIK223235;Homo sapiens (Human)1.2377Known
Q15139Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD15587;Homo sapiens (Human)1.23624Known
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.23493Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)1.23443Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)1.20421Known
Q86YV6Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4340156;Homo sapiens (Human)1.20036Known
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)1.17414Known
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)1.17336Known
Q52WX2Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySBK1388228;Homo sapiens (Human)1.16871Known
P07332Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFES2242;Homo sapiens (Human)1.16621Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.16571Known
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)1.14391Known
Q9P289Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2651765;Homo sapiens (Human)1.14291Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)1.1413Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)1.14004Known
Q15349Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA26196;Homo sapiens (Human)1.13657Known
Q9H2K8Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK351347;Homo sapiens (Human)1.13389Known
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)1.12617Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)1.12504Known
Q15418Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA16195;Homo sapiens (Human)1.12188Known
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)1.1105Known
P78356Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase ...PIP4K2B8396;Homo sapiens (Human)1.10726Known
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.10422Known
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)1.07717Known
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)1.07247Known
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)1.07001Known
Q9BYT3Serine/threonine-protein kinase 33 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilySTK3365975;Homo sapiens (Human)1.06254Known
Q9P286Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK557144;Homo sapiens (Human)1.06138Known
O75676Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA48986;Homo sapiens (Human)1.05604Known
P11802Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK41019;Homo sapiens (Human)1.05147Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)1.0401Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)1.02859Known
Q9NRM7Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS226524;Homo sapiens (Human)1.02826Known
Q15746Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK4638;Homo sapiens (Human)1.02457Known
Q9H422Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK310114;Homo sapiens (Human)1.01678Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)0.997117Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)0.995294Known
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)0.985729Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)0.977646Known
Q9NWZ3Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK451135;Homo sapiens (Human)0.956143Known
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)0.954211Known
Q13523Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familyPRPF4B8899;Homo sapiens (Human)0.945427Known
Q9Y6E0Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK248428;Homo sapiens (Human)0.938608Known
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)0.93598Known
O75385Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) ...Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK18408;Homo sapiens (Human)0.902496Known
Q6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein ...Protein kinase superfamily, Ser/Thr protein kinase familyDSTYK25778;Homo sapiens (Human)0.878532Known
Q15835Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK16011;Homo sapiens (Human)0.874427Known
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)0.867932Known
Q7L7X3Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTAOK157551;Homo sapiens (Human)0.839457Known
P0C264Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family ...Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamilySBK3100130827;Homo sapiens (Human)0.824915Known
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)0.815655Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)0.787731Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)0.787097Known
P54762Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB12047;Homo sapiens (Human)0.781468Known
P54764Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA42043;Homo sapiens (Human)0.753592Known
P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB42050;Homo sapiens (Human)0.749742Known
Q8TDR2Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting ...Protein kinase superfamily, Ser/Thr protein kinase familySTK35140901;Homo sapiens (Human)0.741817Known
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)0.715142Known
Q9UK32Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA627330;Homo sapiens (Human)0.71288Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)0.705437Known
P29323Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB22048;Homo sapiens (Human)0.699953Known
Q16512Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN15585;Homo sapiens (Human)0.670038Known
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)0.65683Known
P37173TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR27048;Homo sapiens (Human)0.652425Known
Q7KZI7Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK22011;Homo sapiens (Human)0.643528Known
Q9UF33Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA6285220;Homo sapiens (Human)0.62999Known
Q6ZN16Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K15389840;Homo sapiens (Human)0.624392Known
P45985Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K46416;Homo sapiens (Human)0.60245Known
O75460Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyERN12081;Homo sapiens (Human)0.602267Known
Q9UIK4Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK223604;Homo sapiens (Human)0.597625Known
O155303-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamilyPDPK15170;Homo sapiens (Human)0.596268Known
P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR17046;Homo sapiens (Human)0.592421Known
P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA32042;Homo sapiens (Human)0.583761Known
O95835Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyLATS19113;Homo sapiens (Human)0.57109Known
O15075Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyDCLK19201;Homo sapiens (Human)0.570831Known
P21709Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA12041;Homo sapiens (Human)0.56395Known
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)0.563601Known
P54756Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA52044;Homo sapiens (Human)0.560749Known
Q96NX5Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1G57172;Homo sapiens (Human)0.55985Known
P53355Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK11612;Homo sapiens (Human)0.557622Known
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)0.547106Known
Q96L34MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK457787;Homo sapiens (Human)0.523315Known
Q8NFD2Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyANKK1255239;Homo sapiens (Human)0.492049Known
Q9BXA7Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyTSSK1B83942;Homo sapiens (Human)0.470538Known
O94768Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17B9262;Homo sapiens (Human)0.469935Known
P27448MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK34140;Homo sapiens (Human)0.462869Known
Q8IU85Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamilyCAMK1D57118;Homo sapiens (Human)0.4606Known
P37023Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVRL194;Homo sapiens (Human)0.46038Known
Q9NQU5Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK6106821730;56924;Homo sapiens (Human)0.454471Known
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)0.452676Known
O15146Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase familyMUSK4593;Homo sapiens (Human)0.438913Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)0.434123Known
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)0.429409Known
P52564Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K65608;Homo sapiens (Human)0.414835Known
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)0.412063Known
Q9P0L2Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyMARK14139;Homo sapiens (Human)0.410657Known
P42680Tyrosine-protein kinase Tec (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTEC7006;Homo sapiens (Human)0.379725Known
Q9Y6R4Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K44216;Homo sapiens (Human)0.373175Known
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)0.352892Known
O00506Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK2510494;Homo sapiens (Human)0.343409Known
P08684Cytochrome P450 3A4 (EC 1.14.14.-) (1,8-cineole 2-exo-monooxygenase) (EC 1.14.14.56) (Albendazole ...Cytochrome P450 familyCYP3A41576;Homo sapiens (Human)0.285198Known
O95382Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K69064;Homo sapiens (Human)0.193759Known

[41] CHEMBL2001751

Original SMILES:
NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12

Prepared SMILES:
NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2

Q9P1W9Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM211040;Homo sapiens (Human)3.6871
P19099Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC ...Cytochrome P450 familyCYP11B21585;Homo sapiens (Human)3.441522
P415955-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)G-protein coupled receptor 1 familyHTR2B3357;Homo sapiens (Human)3.048753
P49286Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)G-protein coupled receptor 1 familyMTNR1B4544;Homo sapiens (Human)3.027144
P48039Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)G-protein coupled receptor 1 familyMTNR1A4543;Homo sapiens (Human)2.763385
Q9Y243RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT310000;Homo sapiens (Human)2.70826
P31749RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT1207;Homo sapiens (Human)2.693617
P282225-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (S12) (Serotonin 1D beta receptor) ...G-protein coupled receptor 1 familyHTR1B3351;Homo sapiens (Human)2.467958
O00519Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide ...Amidase familyFAAH2166;Homo sapiens (Human)2.464369
P31751RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT2208;Homo sapiens (Human)2.4610910
P282215-hydroxytryptamine receptor 1D (5-HT-1D) (5-HT1D) (Serotonin 1D alpha receptor) (5-HT-1D-alpha) ...G-protein coupled receptor 1 familyHTR1D3352;Homo sapiens (Human)2.4566111
P282235-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)G-protein coupled receptor 1 familyHTR2A3356;Homo sapiens (Human)2.4498312
P35372Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid ...G-protein coupled receptor 1 familyOPRM14988;Homo sapiens (Human)2.3407313
P09960Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)Peptidase M1 familyLTA4H4048;Homo sapiens (Human)2.3383114
P07550Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB2 sub-subfamilyADRB2154;Homo sapiens (Human)2.3352115
P089085-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamilyHTR1A3350;Homo sapiens (Human)2.1985116
Q13547Histone deacetylase 1 (HD1) (EC 3.5.1.98)Histone deacetylase family, HD type 1 subfamilyHDAC13065;Homo sapiens (Human)2.1797817
P43681Neuronal acetylcholine receptor subunit alpha-4Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) ...CHRNA41137;Homo sapiens (Human)1.9578618
P11309Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM15292;Homo sapiens (Human)1.953619
P41594Metabotropic glutamate receptor 5 (mGluR5)G-protein coupled receptor 3 familyGRM52915;Homo sapiens (Human)1.9414420
P21917D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)G-protein coupled receptor 1 familyDRD41815;Homo sapiens (Human)1.8594421
Q9Y5N1Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)G-protein coupled receptor 1 familyHRH311255;Homo sapiens (Human)1.8381322
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.834923
P31645Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family ...Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamilySLC6A46532;Homo sapiens (Human)1.7969924
Q86V86Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamilyPIM3415116;Homo sapiens (Human)1.6290725
Q92731Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A ...Nuclear hormone receptor family, NR3 subfamilyESR22100;Homo sapiens (Human)1.6135126
P41145Kappa-type opioid receptor (K-OR-1) (KOR-1)G-protein coupled receptor 1 familyOPRK14986;Homo sapiens (Human)1.596427
P283355-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) ...G-protein coupled receptor 1 familyHTR2C3358;Homo sapiens (Human)1.5849428
P504065-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)G-protein coupled receptor 1 familyHTR63362;Homo sapiens (Human)1.5759529
P27815cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.53) (DPDE2) (PDE46)Cyclic nucleotide phosphodiesterase family, PDE4 subfamilyPDE4A5141;Homo sapiens (Human)1.5499430
P14416D(2) dopamine receptor (Dopamine D2 receptor)G-protein coupled receptor 1 familyDRD21813;Homo sapiens (Human)1.5440331
P35462D(3) dopamine receptor (Dopamine D3 receptor)G-protein coupled receptor 1 familyDRD31814;Homo sapiens (Human)1.5394532
P05177Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cholesterol 25-hydroxylase) (Cytochrome P(3)450) ...Cytochrome P450 familyCYP1A21544;Homo sapiens (Human)1.535133
P32297Neuronal acetylcholine receptor subunit alpha-3Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) ...CHRNA31136;Homo sapiens (Human)1.5053434
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)1.4453435
P03372Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 ...Nuclear hormone receptor family, NR3 subfamilyESR12099;Homo sapiens (Human)1.3897636
O43570Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA12771;Homo sapiens (Human)1.3627837
P15538Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid ...Cytochrome P450 familyCYP11B11584;Homo sapiens (Human)1.3537438
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.3298439
P23141Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) ...Type-B carboxylesterase/lipase familyCES11066;Homo sapiens (Human)1.3270240
P00918Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA2760;Homo sapiens (Human)1.2788641
P13945Beta-3 adrenergic receptor (Beta-3 adrenoreceptor) (Beta-3 adrenoceptor)G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB3 sub-subfamilyADRB3155;Homo sapiens (Human)1.273142
Q16790Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase ...Alpha-carbonic anhydrase familyCA9768;Homo sapiens (Human)1.2500843
Q92769Histone deacetylase 2 (HD2) (EC 3.5.1.98)Histone deacetylase family, HD type 1 subfamilyHDAC23066;Homo sapiens (Human)1.2476344
P349695-hydroxytryptamine receptor 7 (5-HT-7) (5-HT7) (5-HT-X) (Serotonin receptor 7)G-protein coupled receptor 1 familyHTR73363;Homo sapiens (Human)1.2372345
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)1.2130146
P34913Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) ...AB hydrolase superfamily, Epoxide hydrolase familyEPHX22053;Homo sapiens (Human)1.2122547
P08588Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor)G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB1 sub-subfamilyADRB1153;Homo sapiens (Human)1.2070348
Q6GMR7Fatty-acid amide hydrolase 2 (EC 3.5.1.99) (Amidase domain-containing protein) (Anandamide ...Amidase familyFAAH2158584;Homo sapiens (Human)1.1932649
P24941Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK21017;Homo sapiens (Human)1.1926350

Job Information

Job IDSubmitted datePrediction typeMethodNetworkMolecular fingerprintOther parameter(s)Score matrix
233592026-06-26
14:49:21		Target proteinsWeighted Substructure-Drug-Target Network-Based Inference (wSDTNBI)Global drug-target interaction (DTI) network (version 2020)Morgan fingerprint, similar to FCFP_4 Downloadα = 0.4, β = 0.2, γ = -0.5, k = 2, Top 50Download

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