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CompoundTarget IDProtein nameProtein familyGene symbolGene IDOrganismScoreRank

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Original SMILES:
C(=O)(C=C)N

Prepared SMILES:
NC(=O)C=C

Q9NZJ5Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK39451;Homo sapiens (Human)2.957191
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)2.532582
Q06187Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBTK695;Homo sapiens (Human)2.301763
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)2.265314
Q9Y572Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK311035;Homo sapiens (Human)2.244815
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)2.157776
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)2.040997
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)2.000598
P43405Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilySYK6850;Homo sapiens (Human)1.674199
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)1.6633210
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)1.5699211
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.5325812
P15692Vascular endothelial growth factor A (VEGF-A) (Vascular permeability factor) (VPF)PDGF/VEGF growth factor familyVEGFA7422;Homo sapiens (Human)1.5262713
Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK18737;Homo sapiens (Human)1.5121114
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.5062Known
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.4853215
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)1.4057916
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.3765717
P12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilySRC6714;Homo sapiens (Human)1.3651918
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)1.3502619
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)1.2957620
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.2804621
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)1.266422
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)1.2553723
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)1.2377524
Q15375Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA72045;Homo sapiens (Human)1.2114225
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)1.2104326
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)1.2055527
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)1.2042128
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.1969229
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)1.1554230
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)1.1477231
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)1.1300932
Q9BWU1Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK1923097;Homo sapiens (Human)1.1272333
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)1.1147134
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)1.0939535
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)1.0747936
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)1.0472637
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)0.97379438
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)0.96142239
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)0.95107440
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)0.94181641
P43403Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) ...Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamilyZAP707535;Homo sapiens (Human)0.92608542
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)0.92520643
P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB22064;Homo sapiens (Human)0.92352344
P08631Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyHCK3055;Homo sapiens (Human)0.91589645
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)0.861246
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)0.84585247
P21860Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB32065;Homo sapiens (Human)0.8342548
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)0.82378749
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)0.80693950

Job Information

Job IDSubmitted datePrediction typeMethodNetworkMolecular fingerprintOther parameter(s)Score matrix
191252025-11-17
15:05:54		Target proteinsWeighted Substructure-Drug-Target Network-Based Inference (wSDTNBI)Global drug-target interaction (DTI) network (version 2020)Morgan fingerprint, similar to FCFP_4 Downloadα = 0.4, β = 0.2, γ = -0.5, k = 2, Top 50Download

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