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CompoundTarget IDProtein nameProtein familyGene symbolGene IDOrganismScoreRank

[1] Untitled

Original SMILES:
C(=O)(c1c(cccc1)Sc1ccc2c(n[nH]c2c1)/C=C/c1ccccn1)NC

Prepared SMILES:
CNC(=O)c1ccccc1Sc1ccc2c(c1)[nH]nc2/C=C/c1ccccn1

P09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRB5159;Homo sapiens (Human)3.18938Known
P35968Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKDR3791;Homo sapiens (Human)3.14039Known
O00444Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamilyPLK410733;Homo sapiens (Human)2.69253Known
P07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyCSF1R1436;Homo sapiens (Human)2.59965Known
P16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyPDGFRA5156;Homo sapiens (Human)2.51614Known
P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT12321;Homo sapiens (Human)2.47778Known
Q9HAZ1Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK457396;Homo sapiens (Human)2.43971
P29376Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyLTK4058;Homo sapiens (Human)2.234052
P08922Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyROS16098;Homo sapiens (Human)2.22233Known
P36888Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT32322;Homo sapiens (Human)2.20188Known
P21802Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR22263;Homo sapiens (Human)2.17444Known
Q96GD4Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKB9212;Homo sapiens (Human)2.16056Known
Q13163Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K55607;Homo sapiens (Human)2.15668Known
Q9NSY1BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyBMP2K55589;Homo sapiens (Human)2.13515Known
Q56UN5Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP3K1980122;Homo sapiens (Human)2.12382Known
P49760Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK21196;Homo sapiens (Human)2.121283
Q12852Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K127786;Homo sapiens (Human)2.08429Known
O94804Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK106793;Homo sapiens (Human)2.07958Known
Q05397Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion ...Protein kinase superfamily, Tyr protein kinase family, FAK subfamilyPTK25747;Homo sapiens (Human)2.078984
P49759Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamilyCLK11195;Homo sapiens (Human)2.07525
O15197Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHB62051;Homo sapiens (Human)2.06264Known
Q06418Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyTYRO37301;Homo sapiens (Human)2.061376
P10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyKIT3815;Homo sapiens (Human)2.05602Known
Q16288NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK34916;Homo sapiens (Human)2.025517
Q2M2I8AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familyAAK122848;Homo sapiens (Human)2.01551Known
P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like ...Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamilyFLT42324;Homo sapiens (Human)2.01339Known
P16591Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) ...Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamilyFER2241;Homo sapiens (Human)1.991518
Q16620BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK24915;Homo sapiens (Human)1.963469
Q04771Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR190;Homo sapiens (Human)1.9514710
Q9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyALK238;Homo sapiens (Human)1.9460611
P53779Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK105602;Homo sapiens (Human)1.90202Known
O95819Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K49448;Homo sapiens (Human)1.89782Known
Q15303Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyERBB42066;Homo sapiens (Human)1.8936812
O75116Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK29475;Homo sapiens (Human)1.8707613
P07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member ...Protein kinase superfamily, Tyr protein kinase familyRET5979;Homo sapiens (Human)1.82556Known
P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR12260;Homo sapiens (Human)1.8104Known
Q08345Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR1780;Homo sapiens (Human)1.80203Known
Q12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyMERTK10461;Homo sapiens (Human)1.76348Known
P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR32261;Homo sapiens (Human)1.75211Known
P00519Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL125;Homo sapiens (Human)1.74669Known
Q04759Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPRKCQ5588;Homo sapiens (Human)1.7285714
Q9H2G2STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySLK9748;Homo sapiens (Human)1.72646Known
Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK18737;Homo sapiens (Human)1.72273Known
Q13882Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase ...Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamilyPTK65753;Homo sapiens (Human)1.7108515
P57078Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK4Homo sapiens (Human)1.70495Known
P29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyTYK27297;Homo sapiens (Human)1.69618Known
P30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamilyAXL558;Homo sapiens (Human)1.69384Known
Q9UHD2Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyTBK129110;Homo sapiens (Human)1.67849Known
Q8N4C8Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMINK150488;Homo sapiens (Human)1.66347Known
Q9Y616Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK311213;Homo sapiens (Human)1.651716
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase ...Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamilyIKBKE9641;Homo sapiens (Human)1.6487517
O43318Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K76885;Homo sapiens (Human)1.638518
P04629High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyNTRK14914;Homo sapiens (Human)1.63653Known
Q9P2K8eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK4440275;Homo sapiens (Human)1.6200319
O43293Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...DAPK31613;Homo sapiens (Human)1.6041620
P15056Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyBRAF673;Homo sapiens (Human)1.5939821
P22455Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen ...Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor ...FGFR42264;Homo sapiens (Human)1.5924722
Q9UQB9Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKC6795;Homo sapiens (Human)1.59218Known
P23458Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK13716;Homo sapiens (Human)1.5917723
Q08881Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyITK3702;Homo sapiens (Human)1.59061Known
Q13464Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) ...Protein kinase superfamily, AGC Ser/Thr protein kinase familyROCK16093;Homo sapiens (Human)1.5842824
Q9BRS2Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK183732;Homo sapiens (Human)1.56775Known
Q9UKE5TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyTNIK23043;Homo sapiens (Human)1.56345Known
P42685Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFRK2444;Homo sapiens (Human)1.5607625
Q00537Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK175128;Homo sapiens (Human)1.5479926
Q16513Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamilyPKN25586;Homo sapiens (Human)1.53832Known
P51812Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase ...RPS6KA36197;Homo sapiens (Human)1.532427
Q13627Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamilyDYRK1A1859;Homo sapiens (Human)1.5260728
P31749RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamilyAKT1207;Homo sapiens (Human)1.5236329
Q9Y2U5Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K210746;Homo sapiens (Human)1.4964230
Q8IVH8Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K38491;Homo sapiens (Human)1.47396Known
O75716Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) ...Protein kinase superfamily, Ser/Thr protein kinase familySTK168576;Homo sapiens (Human)1.46597Known
Q04912Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase familyMST1R4486;Homo sapiens (Human)1.4603131
O00238Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...BMPR1B658;Homo sapiens (Human)1.45931Known
O14730Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)Protein kinase superfamily, RIO-type Ser/Thr kinase familyRIOK38780;Homo sapiens (Human)1.45195Known
P57059Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamilySIK1102724428;150094;Homo sapiens (Human)1.45129Known
P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type ...Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...TGFBR17046;Homo sapiens (Human)1.4439632
P08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyIGF1R3480;Homo sapiens (Human)1.4373833
P49336Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK81024;Homo sapiens (Human)1.4282134
P42684Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene ...Protein kinase superfamily, Tyr protein kinase family, ABL subfamilyABL227;Homo sapiens (Human)1.41632Known
P45984Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK95601;Homo sapiens (Human)1.4144235
P07948Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLYN4067;Homo sapiens (Human)1.406536
Q16832Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyDDR24921;Homo sapiens (Human)1.40557Known
P04049RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamilyRAF15894;Homo sapiens (Human)1.4015737
P49841Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamilyGSK3B2932;Homo sapiens (Human)1.3796438
Q6PHR2Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK325989;Homo sapiens (Human)1.37236Known
P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamilyEPHA21969;Homo sapiens (Human)1.3717939
O60674Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK23717;Homo sapiens (Human)1.3682Known
Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K15604;Homo sapiens (Human)1.36694Known
Q52WX2Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)Protein kinase superfamily, Ser/Thr protein kinase familySBK1388228;Homo sapiens (Human)1.3642640
Q8NE63Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK4147746;Homo sapiens (Human)1.3529141
Q9UEE5Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase ...STK17A9263;Homo sapiens (Human)1.3506442
Q9NWT8Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, ...Mitochondrion-specific ribosomal protein mS38 familyAURKAIP154998;Homo sapiens (Human)1.3494943
Q9BZL6Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamilyPRKD225865;Homo sapiens (Human)1.3246844
P45983Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase ...MAPK85599;Homo sapiens (Human)1.32094Known
Q32MK0Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK391807;Homo sapiens (Human)1.32075Known
Q9H2X6Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamilyHIPK228996;Homo sapiens (Human)1.3166345
Q12851Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K25871;Homo sapiens (Human)1.31648Known
O60285NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK19891;Homo sapiens (Human)1.3157446
P15735Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase familyPHKG25261;Homo sapiens (Human)1.3144147
P51813Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyBMX660;Homo sapiens (Human)1.3039148
Q9Y5S2Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamilyCDC42BPB9578;Homo sapiens (Human)1.30301Known
P46734Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K35606;Homo sapiens (Human)1.298349
Q92772Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDKL28999;Homo sapiens (Human)1.29264Known
O14965Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamilyAURKA6790;Homo sapiens (Human)1.28218Known
P06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: ...Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamilyINSR3643;Homo sapiens (Human)1.2819550
Q9NYL2Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K2051776;Homo sapiens (Human)1.27576Known
Q99759Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K34215;Homo sapiens (Human)1.27024Known
P32298G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor ...Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamilyGRK42868;Homo sapiens (Human)1.25971Known
Q07912Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine ...Protein kinase superfamily, Tyr protein kinase familyTNK210188;Homo sapiens (Human)1.25495Known
Q8NFD2Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyANKK1255239;Homo sapiens (Human)1.20133Known
Q9UPE1SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK326576;Homo sapiens (Human)1.19524Known
Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial ...Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTEK7010;Homo sapiens (Human)1.18992Known
P00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamilyEGFR1956;Homo sapiens (Human)1.18917Known
Q92918Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K111184;Homo sapiens (Human)1.18641Known
O14976Cyclin-G-associated kinase (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase familyGAK2580;Homo sapiens (Human)1.18058Known
Q5S007Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)Protein kinase superfamily, TKL Ser/Thr protein kinase familyLRRK2120892;Homo sapiens (Human)1.1773Known
P33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein ...Protein kinase superfamily, Ser/Thr protein kinase familyTTK7272;Homo sapiens (Human)1.17506Known
P35590Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)Protein kinase superfamily, Tyr protein kinase family, Tie subfamilyTIE17075;Homo sapiens (Human)1.16555Known
Q96SB4SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase familySRPK16732;Homo sapiens (Human)1.141Known
P08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) ...Protein kinase superfamily, Tyr protein kinase familyMET4233;Homo sapiens (Human)1.13889Known
Q13470Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)Protein kinase superfamily, Tyr protein kinase familyTNK18711;Homo sapiens (Human)1.12744Known
Q9Y4K4Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyMAP4K511183;Homo sapiens (Human)1.12558Known
Q9H1R3Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)Protein kinase superfamily, CAMK Ser/Thr protein kinase familyMYLK285366;Homo sapiens (Human)1.09947Known
P42681Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte ...Protein kinase superfamily, Tyr protein kinase family, TEC subfamilyTXK7294;Homo sapiens (Human)1.07145Known
Q8NEV4Myosin-IIIa (EC 2.7.11.1)TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, ...MYO3A53904;Homo sapiens (Human)1.04355Known
P07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyYES17525;Homo sapiens (Human)1.03355Known
P51451Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyBLK640;Homo sapiens (Human)0.996348Known
Q00536Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) ...Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamilyCDK165127;Homo sapiens (Human)0.981321Known
Q9H093NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyNUAK281788;Homo sapiens (Human)0.979409Known
P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte ...Protein kinase superfamily, Tyr protein kinase family, JAK subfamilyJAK33718;Homo sapiens (Human)0.969541Known
Q9Y6R4Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K44216;Homo sapiens (Human)0.952237Known
Q8N5S9Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK184254;Homo sapiens (Human)0.912786Known
P09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyFGR2268;Homo sapiens (Human)0.902871Known
P80192Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP3K94293;Homo sapiens (Human)0.901923Known
P57058Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase ...Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamilyHUNK30811;Homo sapiens (Human)0.889021Known
O96013Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilyPAK410298;Homo sapiens (Human)0.880364Known
Q8IYT8Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamilyULK29706;Homo sapiens (Human)0.869756Known
P51617Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamilyIRAK13654;Homo sapiens (Human)0.859009Known
Q96RR4Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) ...Protein kinase superfamily, Ser/Thr protein kinase familyCAMKK210645;Homo sapiens (Human)0.85188Known
Q13705Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor ...ACVR2B93;Homo sapiens (Human)0.845958Known
P19784Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamilyCSNK2A21459;Homo sapiens (Human)0.807779Known
Q15569Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyTESK17016;Homo sapiens (Human)0.78344Known
P06239Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) ...Protein kinase superfamily, Tyr protein kinase family, SRC subfamilyLCK3932;Homo sapiens (Human)0.783024Known
Q13043Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK46789;Homo sapiens (Human)0.719192Known
P36507Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase ...Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase ...MAP2K25605;Homo sapiens (Human)0.677112Known
O43353Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated ...Protein kinase superfamily, TKL Ser/Thr protein kinase familyRIPK28767;Homo sapiens (Human)0.627841Known
P41240Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)Protein kinase superfamily, Tyr protein kinase family, CSK subfamilyCSK1445;Homo sapiens (Human)0.613704Known
Q13188Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) ...Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamilySTK36788;Homo sapiens (Human)0.561607Known
Q9NUW8Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-)Tyrosyl-DNA phosphodiesterase familyTDP155775;Homo sapiens (Human)0.409966Known
P19525Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation ...Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamilyEIF2AK25610;Homo sapiens (Human)0.306054Known

Job Information

Job IDSubmitted datePrediction typeMethodNetworkMolecular fingerprintOther parameter(s)Score matrix
190852025-11-17
14:49:04		Target proteinsWeighted Substructure-Drug-Target Network-Based Inference (wSDTNBI)Global drug-target interaction (DTI) network (version 2020)Morgan fingerprint, similar to FCFP_4 Downloadα = 0.4, β = 0.2, γ = -0.5, k = 2, Top 50Download

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