MetaADEDB 2.0 @ LMMD
ximelagatran
(ZXIBCJHYVWYIKI-PZJWPPBQSA-N)
Structure
SMILES
CCOC(=O)CN[C@@H](C(=O)N1CC[C@H]1C(=O)NCc1ccc(cc1)/C(=N/O)/N)C1CCCCC1
Type(s)
Approved; Investigational; Withdrawn
ATC code(s)
B01AE05
Molecular Formula:
C24H35N5O5
Molecular Weight:
473.565
Log P:
2.5198
Hydrogen Bond Acceptor:
10
Hydrogen Bond Donor:
4
TPSA:
146.35
CAS Number(s):
192939-46-1
Synonym(s)
1.
ximelagatran
2.
Exanta
3.
H 376 95
4.
H 376-95
5.
glycine, N-((1)1-cyclohexyl-2-((2)-((((4-(amino(hydroxyimino)methyl)phenyl)methyl)amino)carbonyl)-1-azetidinyl)2-oxoethyl)-ethyl ester
6.
glycine, N-((1R)1-cyclohexyl-2-((2S)-((((4-(amino(hydroxyimino)methyl)phenyl)methyl)amino)carbonyl)-1-azetidinyl)2-oxoethyl)-ethyl ester
7.
xi-melagatran
External Link(s)
MeSHC426686
PubChem Compound656635
5478933
9574101
ChEBI65172
136702
CHEMBLCHEMBL522038
DrugBankDB04898
DrugCentral2852
IUPHAR/BPS Guide to PHARMACOLOGY6381
KEGGdr:D01981
Therapeutic Target DatabaseD0G1UQ
D0JQ7Y
ZINC12504524
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Chemical and Drug Induced Liver Injury17020434
25900201		CTD
2Embolism and Thrombosis16084352CTD
3Embolism16305522
17020434		CTD
4Ischemia16194202
17314111		CTD
5Myocardial Infarction16194202CTD
6Venous Thromboembolism16123915
16305522		CTD
7Venous Thrombosis15903126CTD
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