MetaADEDB 2.0 @ LMMD
prucalopride
(ZPMNHBXQOOVQJL-UHFFFAOYSA-N)
Structure
SMILES
COCCCN1CCC(CC1)NC(=O)c1cc(Cl)c(c2c1OCC2)N
Type(s)
Approved
ATC code(s)
A06AX05
Molecular Formula:
C18H26ClN3O3
Molecular Weight:
367.870
Log P:
2.9978
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
2
TPSA:
76.82
CAS Number(s):
179474-81-8
Synonym(s)
1.
prucalopride
2.
4-amino-5-chloro-N-(1-(3-methoxypropyl)-4-piperidinyl)-2,3-dihydro-1-benzofuran-7-carboxamide
3.
R 093877
4.
R093877
5.
Resolor
6.
resotran
7.
resotrans
External Link(s)
MeSHC406662
PubChem Compound3052762
BindingDB50122872
ChEBI135552
CHEMBLCHEMBL117287
DrugBankDB06480
DrugCentral3502
IUPHAR/BPS Guide to PHARMACOLOGY243
KEGGdr:D09205
Therapeutic Target DatabaseD04QSJ
D0F3ZT
ZINC1891034
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 9US FAERS
2HeadacheFAERS: 9SIDER
US FAERS
3NauseaFAERS: 9SIDER
US FAERS
4Abdominal PainFAERS: 6SIDER
US FAERS
5Bowel movement irregularityFAERS: 4US FAERS
6ConstipationFAERS: 3US FAERS
7VomitingFAERS: 3SIDER
US FAERS
8Abdominal discomfortFAERS: 2US FAERS
9AnxietyFAERS: 2US FAERS
10FatigueFAERS: 2SIDER
US FAERS
11Feeling abnormalFAERS: 2SIDER
US FAERS
12MalaiseFAERS: 2SIDER
US FAERS
13Wrong technique in product usage processFAERS: 2US FAERS
14AstheniaFAERS: 1SIDER
US FAERS
15Chest PainFAERS: 1US FAERS
16DiscomfortFAERS: 1SIDER
US FAERS
17DizzinessFAERS: 1SIDER
US FAERS
18FlatulenceFAERS: 1SIDER
US FAERS
19Inappropriate schedule of product administrationFAERS: 1US FAERS
20PruritusFAERS: 1US FAERS
21Therapeutic product effect increasedFAERS: 1US FAERS
22Unevaluable eventFAERS: 1US FAERS
23Weight decreasedFAERS: 1US FAERS
24Abnormal bowel soundsSIDER
25AnorexiaSIDER
26Back PainSIDER
27DyspepsiaSIDER
28Gastrointestinal PainSIDER
29Gastrointestinal sounds abnormalSIDER
30InfectionSIDER
31InfestationSIDER
32InfluenzaSIDER
33Irritable Bowel Syndrome23330973CTD
34MalnutritionSIDER
35NasopharyngitisSIDER
36PalpitationsSIDER
37PolyuriaSIDER
38SinusitisSIDER
39TremorSIDER
40Urinary tract infectionSIDER
41Urine output increasedSIDER
42nervous system disorderSIDER
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