MetaADEDB 2.0 @ LMMD
Cobicistat
(ZCIGNRJZKPOIKD-CQXVEOKZSA-N)
Structure
SMILES
O=C(N[C@@H](Cc1ccccc1)CC[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)N(Cc1csc(n1)C(C)C)C)CCN1CCOCC1)OCc1cncs1
Type(s)
Approved
ATC code(s)
J05AR09; J05AR14; J05AR15; J05AR18; J05AR22; V03AX03
Molecular Formula:
C40H53N7O5S2
Molecular Weight:
776.023
Log P:
7.1113
Hydrogen Bond Acceptor:
14
Hydrogen Bond Donor:
3
TPSA:
194.5
CAS Number(s):
1004316-88-4
Synonym(s)
1.
Cobicistat
2.
GS 9350
3.
GS-9350
4.
GS9350
5.
Tybost
6.
9350, GS
External Link(s)
MeSHD000069547
PubChem Compound25151504
BindingDB50447471
ChEBI72291
CHEMBLCHEMBL2095208
DrugBankDB09065
DrugCentral4299
IUPHAR/BPS Guide to PHARMACOLOGY7535
KEGGdr:D09881
Therapeutic Target DatabaseD02VJP
D0V4ZN
ZINC85537014
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Prescribed overdoseFAERS: 2US FAERS
2Limb operationFAERS: 1US FAERS
3Abdominal PainSIDER
4AstheniaSIDER
5DermatitisSIDER
6DizzinessSIDER
7DysgeusiaSIDER
8DyspepsiaSIDER
9FatigueSIDER
10FlatulenceSIDER
11Gastrointestinal PainSIDER
12HeadacheSIDER
13MalnutritionSIDER
14Musculoskeletal discomfortSIDER
15MyalgiaSIDER
16NauseaSIDER
17NephrolithiasisSIDER
18Ocular icterusSIDER
19Protein urine presentSIDER
20ProteinuriaSIDER
21PruritusSIDER
22SomnolenceSIDER
23VomitingSIDER
24jaundiceSIDER
25nervous system disorderSIDER
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