MetaADEDB 2.0 @ LMMD
Esketamine
(YQEZLKZALYSWHR-ZDUSSCGKSA-N)
Structure
SMILES
CN[C@@]1(CCCCC1=O)c1ccccc1Cl
Type(s)
Approved; Investigational
ATC code(s)
N01AX14
Molecular Formula:
C13H16ClNO
Molecular Weight:
237.725
Log P:
3.2887
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
1
TPSA:
29.1
CAS Number(s):
33643-46-8
Synonym(s)
1.
Esketamine
External Link(s)
PubChem Compound182137
ChEBI60799
CHEMBLCHEMBL395091
DrugBankDB11823
DrugCentral4468
IUPHAR/BPS Guide to PHARMACOLOGY9152
KEGGdr:D07283
ZINC35999642
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1DissociationFAERS: 8US FAERS
2NauseaFAERS: 7US FAERS
3DizzinessFAERS: 6US FAERS
4VomitingFAERS: 6US FAERS
5AnxietyFAERS: 5US FAERS
6Feeling abnormalFAERS: 3US FAERS
7HeadacheFAERS: 3US FAERS
8Drug ineffectiveFAERS: 2US FAERS
9DysgeusiaFAERS: 2US FAERS
10LethargyFAERS: 2US FAERS
11Nasal discomfortFAERS: 2US FAERS
12SomnolenceFAERS: 2US FAERS
13AgitationFAERS: 1US FAERS
14Cardiac ArrestFAERS: 1US FAERS
15Depressed Level of ConsciousnessFAERS: 1US FAERS
16Depressed moodFAERS: 1US FAERS
17DysarthriaFAERS: 1US FAERS
18Emotional distressFAERS: 1US FAERS
19EpistaxisFAERS: 1US FAERS
20Euphoric moodFAERS: 1US FAERS
21FatigueFAERS: 1US FAERS
22FractureFAERS: 1US FAERS
23General physical health deteriorationFAERS: 1US FAERS
24ImmobileFAERS: 1US FAERS
25Intentional product misuseFAERS: 1US FAERS
26Medication ErrorFAERS: 1US FAERS
27Mental impairmentFAERS: 1US FAERS
28OverdoseFAERS: 1US FAERS
29PainFAERS: 1US FAERS
30PalpitationsFAERS: 1US FAERS
31Product quality issueFAERS: 1US FAERS
32Product use in unapproved indicationFAERS: 1US FAERS
33Therapeutic product effect decreasedFAERS: 1US FAERS
34Therapeutic response unexpectedFAERS: 1US FAERS
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