Polymyxins
(WGRSQPZAOZIPGC-VVYZPAMCSA-N)
Structure
- SMILES
- NCC[C@@H](C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC1=O)CCN)Cc1ccccc1)CC(C)C)CCN)[C@H](O)C)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](NC(=O)O)CCN
- Molecular Formula:
- C48H82N16O14
- Molecular Weight:
- 1107.260
- Log P:
- -0.3332
- Hydrogen Bond Acceptor:
- 30
- Hydrogen Bond Donor:
- 19
- TPSA:
- 510.89
- CAS Number(s):
- 1406-11-7
Synonym(s)
1.
Polymyxins
2.
Polymyxin
3.
Polymyxin M
External Link(s)
| MeSH | D011113 |
| PubChem Compound | 3083714 |
| CHEMBL | CHEMBL1091313 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Erythema | FAERS: 2 | US FAERS | |
| 2 | Blood creatinine increased | FAERS: 1 | US FAERS | |
| 3 | Burning sensation | FAERS: 1 | US FAERS | |
| 4 | Albuminuria | SIDER | ||
| 5 | Ataxia | SIDER | ||
| 6 | Dizziness | SIDER | ||
| 7 | Drowsiness | SIDER | ||
| 8 | Flushing | SIDER | ||
| 9 | Headache | SIDER | ||
| 10 | Meningism | SIDER | ||
| 11 | Musculoskeletal stiffness | SIDER | ||
| 12 | Neck stiffness | SIDER | ||
| 13 | Nuchal Rigidity | SIDER | ||
| 14 | Pain | SIDER | ||
| 15 | Somnolence | SIDER | ||
| 16 | Thrombophlebitis | SIDER | ||
| 17 | Urticaria | SIDER |
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