amrubicin
(VJZITPJGSQKZMX-XDPRQOKASA-N)
Structure
- SMILES
- O[C@@H]1CO[C@H](C[C@@H]1O)O[C@H]1C[C@@](N)(Cc2c1c(O)c1c(c2O)C(=O)c2c(C1=O)cccc2)C(=O)C
- Type(s)
- Investigational
- ATC code(s)
- L01DB10
- Molecular Formula:
- C25H25NO9
- Molecular Weight:
- 483.467
- Log P:
- 1.3321
- Hydrogen Bond Acceptor:
- 10
- Hydrogen Bond Donor:
- 5
- TPSA:
- 176.61
- CAS Number(s):
- 110267-81-7
Synonym(s)
1.
amrubicin
2.
(+)-(7S,9S)-9-acetyl-9-amino-7-((2-deoxy-beta-d-erythro-pentopyranosyl)oxy)-6,11-dihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride
3.
(7S,9S)-9-acetyl-9-amino-7-((2-deoxy-beta-D-erythro-pentopyranosyl)oxy)-7,8,9,10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione hydrochloride
4.
SM 5887
5.
SM-5887
6.
amrubicin hydrochloride
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Chills | FAERS: 1 | US FAERS | |
| 2 | Dizziness | FAERS: 1 | US FAERS | |
| 3 | Escherichia infection | FAERS: 1 | US FAERS | |
| 4 | Fatigue | FAERS: 1 | US FAERS | |
| 5 | Febrile Neutropenia | FAERS: 1 | US FAERS | |
| 6 | Gram stain positive | FAERS: 1 | US FAERS | |
| 7 | Leukopenia | FAERS: 1 | US FAERS | |
| 8 | Neutropenia | FAERS: 1 | US FAERS | |
| 9 | Pallor | FAERS: 1 | US FAERS | |
| 10 | Pneumonia | FAERS: 1 | US FAERS | |
| 11 | Urinary Retention | FAERS: 1 | US FAERS | |
| 12 | Bone Marrow Diseases | 14662027 | CTD |
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