methylamphotericin B
(UAZIZEMIKKIBCA-TYVGYKFWSA-N)
Structure
- SMILES
- COC(=O)[C@H]1[C@@H]2C[C@H](/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@H]([C@H]([C@@H](OC(=O)C[C@@H](C[C@@H](CC[C@H]([C@@H](C[C@@H](C[C@@](O2)(C[C@@H]1O)O)O)O)O)O)O)C)C)O)O[C@@H]1O[C@H](C)[C@H]([C@@H]([C@@H]1O)N)O
- Molecular Formula:
- C48H75NO17
- Molecular Weight:
- 938.106
- Log P:
- 1.5004
- Hydrogen Bond Acceptor:
- 18
- Hydrogen Bond Donor:
- 11
- TPSA:
- 308.61
- CAS Number(s):
- 36148-89-7
Synonym(s)
1.
methylamphotericin B
2.
AME
3.
SQ 20,627
4.
amphotericin B methyl ester
5.
metamphocin
6.
methylamphotericin B acetate
7.
methylamphotericin B hydrochloride
External Link(s)
| MeSH | C017501 |
| PubChem Compound | 11968030 |
| ChEBI | 277842 |
| CHEMBL | CHEMBL321176 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Chemical and Drug Induced Liver Injury | 3967472 | CTD | |
| 2 | Dementia | 7108268 | CTD | |
| 3 | Demyelinating Diseases | 3967472 | CTD | |
| 4 | Gliosis | 3967472 7108268 | CTD | |
| 5 | Kidney Diseases | 22863853 | CTD | |
| 6 | Mutism | 7108268 | CTD | |
| 7 | Necrosis | 22863853 | CTD | |
| 8 | Reflex, Abnormal | 7108268 | CTD | |
| 9 | Tremor | 7108268 | CTD |
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