brucine
(RRKTZKIUPZVBMF-IBTVXLQLSA-N)
Structure
- SMILES
- COc1cc2c(cc1OC)N1[C@@H]3[C@@]42CCN2[C@H]4C[C@@H]4[C@H]3[C@H](CC1=O)OCC=C4C2
- Molecular Formula:
- C23H26N2O4
- Molecular Weight:
- 394.464
- Log P:
- 2.1126
- Hydrogen Bond Acceptor:
- 6
- Hydrogen Bond Donor:
- 0
- TPSA:
- 51.24
- CAS Number(s):
- 357-57-3; 145428-94-0
Synonym(s)
1.
brucine
2.
10,11-dimethoxystrychnine
3.
bruzin
4.
dimethoxystrychnine
External Link(s)
| MeSH | C083806 |
| PubChem Compound | 442021 |
| BindingDB | 50401037 |
| ChEBI | 3193 |
| CHEMBL | CHEMBL501756 |
| IUPHAR/BPS Guide to PHARMACOLOGY | 342 |
| KEGG | cpd:C09084 |
| Therapeutic Target Database | D0H2UT |
| ZINC | 1069090 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Acute kidney injury | 19694317 | CTD | |
| 2 | Hepatomegaly | 24060683 | CTD | |
| 3 | Liver Neoplasms, Experimental | 24060683 | CTD | |
| 4 | Liver neoplasms | 21761723 | CTD | |
| 5 | Multiple Myeloma | 21518496 | CTD | |
| 6 | Neoplasm Metastasis | 23933019 | CTD | |
| 7 | Neoplasms, Experimental | 21684292 | CTD | |
| 8 | Rhabdomyolysis | 19694317 | CTD |
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