MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Colistin

(RPABDKTXMKOGKI-OYTUFZPASA-N)

Structure

SMILES: NCC[C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CC(C)C)CCNC(=O)CCCCC(CC)C)[C@H](O)C)CCN
Molecular Formula:: C45H85N13O10
Molecular Weight:: 968.238
Log P:: 2.6819
Hydrogen Bond Acceptor:: 23
Hydrogen Bond Donor:: 14
TPSA:: 386.21
CAS Number(s):: N/A

Synonym(s)

Colistin

Polymyxin E

Colimycin

Colisticin

Colistin Sulfate

Coly-Mycin

Totazina

Sulfate, Colistin

External Link(s)

Adverse Drug Event(s)

	Name	Data Source
1	Abdominal discomfort	SIDER
2	Anxiety	SIDER
3	Arthralgia	SIDER
4	Asthenia	SIDER
5	Asthma	SIDER
6	Blood creatinine decreased	SIDER
7	Blood creatinine increased	SIDER
8	Blood urea increased	SIDER
9	Bronchospasm	SIDER
10	Chest Pain	SIDER
11	Chest discomfort	SIDER
12	Creatinine increased	SIDER
13	Creatinine low	SIDER
14	Dermatitis	SIDER
15	Dizziness	SIDER
16	Dysarthria	SIDER
17	Dysgeusia	SIDER
18	Dysphonia	SIDER
19	Dyspnoea exacerbated	SIDER
20	Ear and labyrinth disorders	SIDER
21	Ear congestion	SIDER
22	Epistaxis	SIDER
23	Fatigue	SIDER
24	Flatulence	SIDER
25	Headache	SIDER
26	Hypersensitivity	SIDER
27	Increased upper airway secretion	SIDER
28	Lower respiratory tract infection	SIDER
29	Malnutrition	SIDER
30	Musculoskeletal discomfort	SIDER
31	Nausea	SIDER
32	Oliguria	SIDER
33	Oropharyngeal discomfort	SIDER
34	Oropharyngeal pain	SIDER
35	Pharyngolaryngeal Pain	SIDER
36	Productive Cough	SIDER
37	Protein urine present	SIDER
38	Proteinuria	SIDER
39	Rales	SIDER
40	Respiratory distress	SIDER
41	Slurred speech	SIDER
42	Somnolence	SIDER
43	Thirst	SIDER
44	Throat irritation	SIDER
45	Tingling of extremity	SIDER
46	Tinnitus	SIDER
47	Toothache	SIDER
48	Urticaria	SIDER
49	Vertigo	SIDER
50	Vomiting	SIDER
51	Wheezing	SIDER
52	nervous system disorder	SIDER

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