pimavanserin
(RKEWSXXUOLRFBX-UHFFFAOYSA-N)
Structure
- SMILES
- CC(COc1ccc(cc1)CNC(=O)N(C1CCN(CC1)C)Cc1ccc(cc1)F)C
- Type(s)
- Approved; Investigational
- ATC code(s)
- N05AX17
- Molecular Formula:
- C25H34FN3O2
- Molecular Weight:
- 427.555
- Log P:
- 4.9953
- Hydrogen Bond Acceptor:
- 5
- Hydrogen Bond Donor:
- 1
- TPSA:
- 44.81
- CAS Number(s):
- 706779-91-1
Synonym(s)
1.
pimavanserin
2.
ACP 103
3.
ACP-103
4.
ACP103
5.
N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl)carbamide
6.
Nuplazid
7.
bis(1-(4-fluorobenzyl)-1-(1-methylpiperidin-4-yl)-3-(4-(2-methylpropoxy)benzyl)urea) (2R,3R)-2,3-dihydroxybutanedioate
8.
pimavanserin tartrate
9.
urea, n-((4-fluorophenyl)methyl)-n-(1-methyl-4-piperidinyl)-n'-((4-(2-methylpropoxy)phenyl)methyl)-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Therapeutic response unexpected | FAERS: 8 | US FAERS | |
| 2 | Drug ineffective | FAERS: 7 | US FAERS | |
| 3 | Asthenia | FAERS: 3 | US FAERS | |
| 4 | Mental status changes | FAERS: 3 | US FAERS | |
| 5 | Agitation | FAERS: 2 | US FAERS | |
| 6 | Nausea | FAERS: 2 | US FAERS | |
| 7 | Nonspecific reaction | FAERS: 2 | US FAERS | |
| 8 | Somnolence | FAERS: 2 | US FAERS | |
| 9 | Anoxia | FAERS: 1 | US FAERS | |
| 10 | Blindness | FAERS: 1 | US FAERS | |
| 11 | Bradycardia | FAERS: 1 | US FAERS | |
| 12 | Cardiac Arrest | FAERS: 1 | US FAERS | |
| 13 | Chest Pain | FAERS: 1 | US FAERS | |
| 14 | Choking | FAERS: 1 | US FAERS | |
| 15 | Constipation | FAERS: 1 | US FAERS | |
| 16 | Delirium | FAERS: 1 | US FAERS | |
| 17 | Disorientation | FAERS: 1 | US FAERS | |
| 18 | Dizziness | FAERS: 1 | US FAERS | |
| 19 | Drooling | FAERS: 1 | US FAERS | |
| 20 | Inappropriate schedule of product administration | FAERS: 1 | US FAERS | |
| 21 | Malaise | FAERS: 1 | US FAERS | |
| 22 | Muscle Rigidity | FAERS: 1 | US FAERS | |
| 23 | Paranoia | FAERS: 1 | US FAERS | |
| 24 | Syncope | FAERS: 1 | US FAERS | |
| 25 | Therapeutic product effect decreased | FAERS: 1 | US FAERS | |
| 26 | Therapy non-responder | FAERS: 1 | US FAERS | |
| 27 | Akathisia, Drug-Induced | 19040345 | CTD | |
| 28 | Catalepsy | 17519387 | CTD | |
| 29 | Dyskinesia, Drug-Induced | 18534670 | CTD | |
| 30 | Psychoses, Substance-Induced | 19040345 | CTD | |
| 31 | Schizophrenia | 19040345 | CTD | |
| 32 | Tremor | 18534670 | CTD |
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