MetaADEDB 2.0 @ LMMD
Thrombin
(PVPBBTJXIKFICP-UHFFFAOYSA-N)
Structure
SMILES
Nc1ccc2c(c1)sc1c(n2)ccc(=N)c1.Cl
Molecular Formula:
C12H10ClN3S
Molecular Weight:
263.746
Log P:
3.9457
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
3
TPSA:
91
CAS Number(s):
581-64-6; 635-76-7; 16178-66-8
Synonym(s)
1.
Thrombin
2.
Thrombase
3.
Thrombin JMI
4.
Thrombin-JMI
5.
Thrombinar
6.
Thrombostat
7.
alpha-Thrombin
8.
beta,gamma-Thrombin
9.
beta-Thrombin
10.
gamma-Thrombin
11.
JMI, Thrombin
External Link(s)
MeSHD013917
PubChem Compound65043
65045
ChEBI52295
CHEMBLCHEMBL1817786
CHEMBL593252
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1EpistaxisFAERS: 3US FAERS
2Factor V deficiencyFAERS: 3US FAERS
3Factor V inhibitionFAERS: 3US FAERS
4Retinal Vascular DisorderFAERS: 3US FAERS
5Cardiac ArrestFAERS: 2US FAERS
6Accidental exposure to productFAERS: 1US FAERS
7Accidental exposureFAERS: 1US FAERS
8Acquired antithrombin III deficiencyFAERS: 1US FAERS
9Anti factor V antibody positiveFAERS: 1US FAERS
10Anti-thrombin antibodyFAERS: 1US FAERS
11Blood creatinine increasedFAERS: 1US FAERS
12Cerebrovascular accidentFAERS: 1US FAERS
13Coagulation factor V level decreasedFAERS: 1US FAERS
14Coagulation test abnormalFAERS: 1US FAERS
15CyanosisFAERS: 1US FAERS
16Disseminated Intravascular CoagulationFAERS: 1US FAERS
17Drug effect incompleteFAERS: 1US FAERS
18Drug ineffectiveFAERS: 1US FAERS
19Factor II inhibitionFAERS: 1US FAERS
20Factor X inhibitionFAERS: 1US FAERS
21Immune-mediated adverse reactionFAERS: 1US FAERS
22Incorrect route of drug administrationFAERS: 1US FAERS
23Mental status changesFAERS: 1US FAERS
24Occupational exposure to productFAERS: 1US FAERS
25PainFAERS: 1US FAERS
26Post procedural pulmonary embolismFAERS: 1US FAERS
27Product physical issueFAERS: 1US FAERS
28Product quality issueFAERS: 1US FAERS
29Product use issueFAERS: 1US FAERS
30Respiratory FailureFAERS: 1US FAERS
31SepsisFAERS: 1US FAERS
32Suture related complicationFAERS: 1US FAERS
33ThrombosisFAERS: 1US FAERS
34UrticariaFAERS: 1US FAERS
35Wrong drug administeredFAERS: 1US FAERS
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