folfirinox
(PJZDLZXMGBOJRF-CXOZILEQSA-L)
Structure
- SMILES
- [O-]C(=O)C(=O)[O-].[NH-][C@H]1CCCC[C@@H]1[NH-].Fc1c[nH]c(=O)[nH]c1=O.CC[C@@]1(O)C(=O)OCc2c1cc1c3nc4ccc(cc4c(c3Cn1c2=O)CC)OC(=O)N1CCC(CC1)N1CCCCC1.O=CN1C(CNc2ccc(cc2)C(=O)N[C@H](C(=O)O)CCC(=O)O)CNc2c1c(=O)[nH]c(n2)N.[Pt+4]
- Molecular Formula:
- C65H76FN15O19Pt
- Molecular Weight:
- 1585.460
- Log P:
- 3.2078
- Hydrogen Bond Acceptor:
- 29
- Hydrogen Bond Donor:
- 12
- TPSA:
- 504.08
- CAS Number(s):
- N/A
Synonym(s)
1.
folfirinox
2.
leucovorin, fluorouracil, irinotecan, oxaliplatin drug combination
External Link(s)
| MeSH | C000627770 |
| PubChem Compound | 136171075 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Febrile Neutropenia | FAERS: 2 | US FAERS | |
| 2 | Acute kidney injury | FAERS: 1 | US FAERS | |
| 3 | Dehydration | FAERS: 1 | US FAERS | |
| 4 | Myocardial Infarction | FAERS: 1 | US FAERS |
Powered by :
Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120331
Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.