Demeclocycline
(OAPVUSSHCBRCOL-KBHRXELFSA-N)
Structure
- SMILES
- CN([C@@H]1C(=O)C(=C([C@@]2([C@H]1C[C@H]1C(=C(O)c3c([C@H]1O)c(Cl)ccc3O)C2=O)O)O)C(=O)N)C.Cl
- Molecular Formula:
- C21H22Cl2N2O8
- Molecular Weight:
- 501.314
- Log P:
- 1.6106
- Hydrogen Bond Acceptor:
- 10
- Hydrogen Bond Donor:
- 7
- TPSA:
- 181.62
- CAS Number(s):
- 64-73-3
Synonym(s)
1.
Demeclocycline
2.
Demethylchlortetracycline
3.
Declomycin
4.
Demeclocycline Hydrochloride
5.
Demeclocycline Monohydrochloride
6.
Demeclocycline, 4-epimer
7.
Demeclocycline, Calcium (1:1) Salt
8.
Demeclocycline, Calcium (1:2) Salt
9.
Ledermycin
10.
Lédermycine
11.
Hydrochloride, Demeclocycline
12.
Monohydrochloride, Demeclocycline
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Hypersensitivity | FAERS: 2 | US FAERS | |
| 2 | Abdominal discomfort | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 3 | Medication Error | FAERS: 1 | US FAERS | |
| 4 | Nausea | FAERS: 1 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 5 | Vomiting | FAERS: 1 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 6 | Angioedema | Canada Vigilance: 1 | Canada Vigilance | |
| 7 | Asthenia | Canada Vigilance: 1 | Canada Vigilance | |
| 8 | Dermatitis | Canada Vigilance: 1 | Canada Vigilance | |
| 9 | Dysphonia | Canada Vigilance: 1 | Canada Vigilance | |
| 10 | Erythema Multiforme | Canada Vigilance: 1 | Canada Vigilance | |
| 11 | Erythema | Canada Vigilance: 7 | Canada Vigilance | |
| 12 | Flushing | Canada Vigilance: 3 | Canada Vigilance | |
| 13 | Gastritis | Canada Vigilance: 1 | Canada Vigilance | |
| 14 | Gingivitis | Canada Vigilance: 1 | Canada Vigilance | |
| 15 | Glossitis | Canada Vigilance: 1 | Canada Vigilance | |
| 16 | Inflammation | Canada Vigilance: 1 | Canada Vigilance | |
| 17 | Malaise | Canada Vigilance: 1 | Canada Vigilance | |
| 18 | Pruritus | Canada Vigilance: 5 | Canada Vigilance | |
| 19 | Purpura | Canada Vigilance: 1 | Canada Vigilance | |
| 20 | Rash erythematous | Canada Vigilance: 1 | Canada Vigilance | |
| 21 | Respiratory Failure | Canada Vigilance: 1 | Canada Vigilance | |
| 22 | Respiratory tract congestion | Canada Vigilance: 1 | Canada Vigilance | |
| 23 | Shock | Canada Vigilance: 1 | Canada Vigilance | |
| 24 | Stomatitis | Canada Vigilance: 1 | Canada Vigilance | |
| 25 | Sunburn | Canada Vigilance: 1 | Canada Vigilance | |
| 26 | Swelling | Canada Vigilance: 1 | Canada Vigilance | |
| 27 | Tachycardia | Canada Vigilance: 1 | Canada Vigilance | |
| 28 | Urticaria | Canada Vigilance: 8 | Canada Vigilance | |
| 29 | Wheezing | Canada Vigilance: 1 | Canada Vigilance |
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