MetaADEDB 2.0 @ LMMD
biapenem
(MRMBZHPJVKCOMA-YJFSRANCSA-N)
Structure
SMILES
C[C@H]([C@H]1C(=O)N2[C@@H]1[C@@H](C)C(=C2C(=O)[O-])SC1C[n+]2n(C1)cnc2)O
Type(s)
Investigational
ATC code(s)
J01DH05
Molecular Formula:
C15H18N4O4S
Molecular Weight:
350.393
Log P:
-1.9571
Hydrogen Bond Acceptor:
8
Hydrogen Bond Donor:
1
TPSA:
127.67
CAS Number(s):
120410-24-4
Synonym(s)
1.
biapenem
2.
3-((6,7-dihydro-5H-pyrazolo(1,2-a)(1,2,4)triazol-4-ium-6-yl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3,2,0)hept-2-ene-2-carboxylate
3.
CLI 86,815
4.
CLI 86815
5.
CLI-86815
6.
L 627
7.
L-627
8.
LJC 10627
9.
LJC-10627
10.
LJC10,627
External Link(s)
MeSHC065257
PubChem Compound71339
ChEBI3089
CHEMBLCHEMBL285347
DrugBankDB13028
DrugCentral365
KEGGcpd:C11268
dr:D01057
Therapeutic Target DatabaseD0E7QN
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Acute graft versus host disease in intestineOFFSIDES
2AdenocarcinomaOFFSIDES
3Alanine Aminotransferase IncreasedOFFSIDES
4Allogenic bone marrow transplantation therapyOFFSIDES
5Altered state of consciousnessOFFSIDES
6AnosmiaOFFSIDES
7Bile Duct StenosisOFFSIDES
8Blood GlucoseOFFSIDES
9Blood albumin decreasedOFFSIDES
10Blood creatinine increasedOFFSIDES
11Blood fibrinogen increasedOFFSIDES
12Blood glucose decreasedOFFSIDES
13Blood lactate dehydrogenase increasedOFFSIDES
14Blood potassium decreasedOFFSIDES
15Blood sodiumOFFSIDES
16Blood urea increasedOFFSIDES
17Blood uric acidOFFSIDES
18BronchopneumoniaOFFSIDES
19Clostridium difficile colitisOFFSIDES
20Colonic fistulaOFFSIDES
21Depressed Level of ConsciousnessOFFSIDES
22Disseminated Intravascular CoagulationOFFSIDES
23Duodenal perforationOFFSIDES
24Fungus serology test positiveOFFSIDES
25Gamma-Glutamyltransferase IncreasedOFFSIDES
26Gastrointestinal infectionOFFSIDES
27General nutrition disorderOFFSIDES
28GlaucomaOFFSIDES
29HypercapniaOFFSIDES
30HypoxiaOFFSIDES
31Kidney FailureOFFSIDES
32Leukopenia neonatalOFFSIDES
33Lymphocyte count decreasedOFFSIDES
34Metabolic acidosisOFFSIDES
35Neutrophil count decreasedOFFSIDES
36OsteomyelitisOFFSIDES
37PO2 decreasedOFFSIDES
38PeritonitisOFFSIDES
39PolyuriaOFFSIDES
40Protein total decreasedOFFSIDES
41Prothrombin level decreasedOFFSIDES
42Respiratory FailureOFFSIDES
43Retinoic acid syndromeOFFSIDES
44Septic ShockOFFSIDES
45Skin ErosionOFFSIDES
46Systemic mycosisOFFSIDES
47Therapy non-responderOFFSIDES
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120237

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.