MetaADEDB 2.0 @ LMMD
Orphenadrine
(MMMNTDFSPSQXJP-UHFFFAOYSA-N)
Structure
SMILES
OC(=O)C(CC(=O)O)(CC(=O)O)O.CN(CCOC(c1ccccc1C)c1ccccc1)C
Molecular Formula:
C24H31NO8
Molecular Weight:
461.505
Log P:
2.4141
Hydrogen Bond Acceptor:
9
Hydrogen Bond Donor:
4
TPSA:
144.6
CAS Number(s):
4596-23-0; 4682-36-4; 4724-58-7
Synonym(s)
1.
Orphenadrine
2.
Methyldiphenylhydramine
3.
Disipal
4.
Lysantin
5.
Mefenamine
6.
Mephenamine
7.
Norflex
8.
Norflex Orphenadrine Citrate
9.
Orphenadrine Citrate
10.
Orphenadrine Hydrochloride
11.
Sodium Mefenamine
12.
Citrate, Norflex Orphenadrine
13.
Citrate, Orphenadrine
14.
Hydrochloride, Orphenadrine
15.
Mefenamine, Sodium
16.
Orphenadrine Citrate, Norflex
External Link(s)
MeSHD009966
PubChem Compound20846
83823
ChEBI7790
CHEMBLCHEMBL1200395
KEGGdr:D00774
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Dry skinFAERS: 3US FAERS
2NauseaFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
3RhabdomyolysisFAERS: 3US FAERS
4Suicide attemptFAERS: 3US FAERS
5AnxietyFAERS: 2US FAERS
6Cervicobrachial syndromeFAERS: 2US FAERS
7Musculoskeletal PainFAERS: 2US FAERS
8Status EpilepticusFAERS: 2US FAERS
9StuporFAERS: 2US FAERS
10TachycardiaFAERS: 2US FAERS
11AgitationFAERS: 1US FAERS
12AstheniaFAERS: 1US FAERS
13Back PainFAERS: 1US FAERS
14Compression fractureFAERS: 1US FAERS
15DeliriumFAERS: 1US FAERS
16Drug toxicityFAERS: 1US FAERS
17DysgraphiaFAERS: 1US FAERS
18DysphoniaFAERS: 1US FAERS
19Electrocardiogram ST-T changeFAERS: 1US FAERS
20HeadacheFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
21Injection site painFAERS: 1US FAERS
22Joint Range of Motion DecreasedFAERS: 1US FAERS
23Medication ErrorFAERS: 1US FAERS
24Mental status changesFAERS: 1US FAERS
25OverdoseFAERS: 1US FAERS
26Partner stressFAERS: 1US FAERS
27Product quality issueFAERS: 1US FAERS
28Product substitution issueFAERS: 1US FAERS
29RadiculopathyFAERS: 1US FAERS
30Sinus TachycardiaFAERS: 1US FAERS
31Sleep TalkingFAERS: 1US FAERS
32SomnolenceFAERS: 1
Canada Vigilance: 2		Canada Vigilance
US FAERS
33SyncopeFAERS: 1US FAERS
34TremorFAERS: 1US FAERS
35Urinary RetentionFAERS: 1US FAERS
36DizzinessCanada Vigilance: 1Canada Vigilance
37LethargyCanada Vigilance: 1Canada Vigilance
38VomitingCanada Vigilance: 1Canada Vigilance
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