dabrafenib
(MLSAQOINCGAULQ-QFMPWRQOSA-N)
Structure
- SMILES
- O/N=C/1\CCc2c1ccc(c2)c1nc([nH]c1c1ccncc1)c1ccc(cc1)OCCN(C)C
- Molecular Formula:
- C27H27N5O2
- Molecular Weight:
- 453.536
- Log P:
- 4.8706
- Hydrogen Bond Acceptor:
- 6
- Hydrogen Bond Donor:
- 2
- TPSA:
- 86.63
- CAS Number(s):
- 405554-55-4
Synonym(s)
1.
dabrafenib
2.
GSK 2118436
3.
GSK-2118436
4.
GSK2118436
External Link(s)
| MeSH | C561627 |
| PubChem Compound | 135421339 |
| ChEBI | 131881 |
| CHEMBL | CHEMBL477989 |
| ZINC | 100061199 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Fatigue | FAERS: 2 | US FAERS | |
| 2 | Accidental overdose | FAERS: 1 | US FAERS | |
| 3 | Arthralgia | FAERS: 1 | US FAERS | |
| 4 | Erythema Multiforme | FAERS: 1 | US FAERS | |
| 5 | Hyperkeratosis | FAERS: 1 | US FAERS | |
| 6 | Otitis Media | FAERS: 1 | US FAERS |
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