MetaADEDB 2.0 @ LMMD
chlorphenamine, dextromethorphan, phenylephrine drug combination
(MKXZASYAUGDDCJ-CGTJXYLNSA-N)
Structure
SMILES
COc1ccc2c(c1)[C@]13CCCC[C@H]3[C@@H](C2)N(CC1)C
Molecular Formula:
C18H25NO
Molecular Weight:
271.397
Log P:
3.3213
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
0
TPSA:
12.47
CAS Number(s):
125-70-2; 510-53-2
Synonym(s)
1.
chlorphenamine, dextromethorphan, phenylephrine drug combination
2.
Cardec DM
3.
Cardec-DM
4.
Rondec DM
5.
RondecDM
6.
chlorphenamine - dextromethorphan - phenylephrine
External Link(s)
MeSHC550887
PubChem Compound5362449
ChEBI146176
CHEMBLCHEMBL1908323
ZINC402848
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug abuseFAERS: 13US FAERS
2HypersensitivityFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
3Incorrect dose administeredFAERS: 4US FAERS
4OverdoseFAERS: 4US FAERS
5DizzinessFAERS: 3US FAERS
6Drug DependenceFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
7EpistaxisFAERS: 3US FAERS
8Rash erythematousFAERS: 3US FAERS
9AstheniaFAERS: 2US FAERS
10Cerebrovascular accidentFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
11ChokingFAERS: 2US FAERS
12DependenceFAERS: 2US FAERS
13Drug ineffectiveFAERS: 2
Canada Vigilance: 2		Canada Vigilance
US FAERS
14Medication ErrorFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
15NauseaFAERS: 2US FAERS
16Product quality issueFAERS: 2US FAERS
17Product taste abnormalFAERS: 2US FAERS
18RetchingFAERS: 2US FAERS
19SneezingFAERS: 2US FAERS
20SomnolenceFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
21ThrombosisFAERS: 2US FAERS
22UrticariaFAERS: 2
Canada Vigilance: 2		Canada Vigilance
US FAERS
23VomitingFAERS: 2US FAERS
24Abdominal discomfortFAERS: 1US FAERS
25Accidental overdoseFAERS: 1US FAERS
26AneurysmFAERS: 1US FAERS
27AnxietyFAERS: 1US FAERS
28ApathyFAERS: 1US FAERS
29AphagiaFAERS: 1US FAERS
30Atrial FibrillationFAERS: 1US FAERS
31Blood glucose decreasedFAERS: 1US FAERS
32Chest discomfortFAERS: 1US FAERS
33Circumstance or information capable of leading to medication errorFAERS: 1US FAERS
34Cold sweatFAERS: 1US FAERS
35Depressed Level of ConsciousnessFAERS: 1US FAERS
36Drug administration errorFAERS: 1US FAERS
37Drug dispensing errorFAERS: 1US FAERS
38DysgeusiaFAERS: 1US FAERS
39Electrocardiogram abnormalFAERS: 1US FAERS
40Embolic strokeFAERS: 1US FAERS
41Emotional distressFAERS: 1US FAERS
42Euphoric moodFAERS: 1US FAERS
43Gastrointestinal PainFAERS: 1US FAERS
44Intentional drug misuseFAERS: 1US FAERS
45Intentional product misuseFAERS: 1US FAERS
46LaryngitisFAERS: 1US FAERS
47MalaiseFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
48Morbid thoughtsFAERS: 1US FAERS
49NervousnessFAERS: 1US FAERS
50No adverse eventFAERS: 1US FAERS
51No reaction on previous exposure to drugFAERS: 1US FAERS
52Product label issueFAERS: 1US FAERS
53Product use issueFAERS: 1US FAERS
54Skin reactionFAERS: 1US FAERS
55TheftFAERS: 1US FAERS
56Therapeutic response unexpectedFAERS: 1US FAERS
57Unevaluable eventFAERS: 1US FAERS
58Unresponsive to stimuliFAERS: 1US FAERS
59Urinary IncontinenceFAERS: 1US FAERS
60Abdominal PainCanada Vigilance: 2Canada Vigilance
61AtaxiaCanada Vigilance: 1Canada Vigilance
62ChillsCanada Vigilance: 2Canada Vigilance
63DiplopiaCanada Vigilance: 1Canada Vigilance
64DisorientationCanada Vigilance: 1Canada Vigilance
65ErythemaCanada Vigilance: 1Canada Vigilance
66Expired product administeredCanada Vigilance: 1Canada Vigilance
67Visual ImpairmentCanada Vigilance: 1Canada Vigilance
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120329

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.