CB 3717
(LTKHPMDRMUCUEB-UHFFFAOYSA-N)
Structure
- SMILES
- C#CCN(c1ccc(cc1)C(=O)NC(C(=O)O)CCC(=O)O)Cc1ccc2c(c1)c(=O)[nH]c(n2)N
- Molecular Formula:
- C24H23N5O6
- Molecular Weight:
- 477.469
- Log P:
- 2.1650
- Hydrogen Bond Acceptor:
- 10
- Hydrogen Bond Donor:
- 5
- TPSA:
- 178.71
- CAS Number(s):
- 76849-19-9
Synonym(s)
1.
CB 3717
2.
5,8-dideaza-N(10)propargylfolic acid
3.
CB-3717
4.
CB3717
5.
ICI 155387
6.
ICI-155387
7.
N(10)-propargyl-5,8-dideazafolate
8.
N-(4-(N-((2-amino-3,4-dihydro-4-oxo-6-quinazolinyl)methyl)-N-prop-2-ynylamino)benzoyl)glutamic acid
9.
NSC 327182
10.
NSC-327182
11.
PDDF
12.
n-(4(N-((2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino)benzoyl)-L-glutamic acid
External Link(s)
| MeSH | C031662 |
| PubChem Compound | 135402053 |
| BindingDB | 50008294 |
| CHEMBL | CHEMBL422395 |
| Therapeutic Target Database | D09YOD |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Acute kidney injury | 1913620 3383974 | CTD | |
| 2 | Chemical and Drug Induced Liver Injury | 3383974 3431591 | CTD | |
| 3 | Fatigue | 3383974 3431591 | CTD | |
| 4 | Hyperplasia | 10354516 | CTD | |
| 5 | Kidney Diseases | 1931603 3431591 | CTD | |
| 6 | Mesothelioma | 3431591 | CTD |
Powered by :
Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120262
Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.