Rilpivirine
(KZVVGZKAVZUACK-BJILWQEISA-N)
Structure
- SMILES
- N#C/C=C/c1cc(C)c(c(c1)C)Nc1ccnc(n1)Nc1ccc(cc1)C#N.Cl
- Molecular Formula:
- C22H19ClN6
- Molecular Weight:
- 402.879
- Log P:
- 5.9371
- Hydrogen Bond Acceptor:
- 4
- Hydrogen Bond Donor:
- 3
- TPSA:
- 97.42
- CAS Number(s):
- 700361-47-3
Synonym(s)
1.
Rilpivirine
2.
R278474
3.
Rilpivirine HCl
4.
Rilpivirine Hydrochloride
5.
TMC 278
6.
TMC-278
7.
TMC278
8.
278, TMC
9.
HCl, Rilpivirine
10.
Hydrochloride, Rilpivirine
External Link(s)
| MeSH | D000068696 |
| PubChem Compound | 11711114 |
| ChEBI | 68602 |
| CHEMBL | CHEMBL1628504 |
| KEGG | dr:D09958 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Hepatitis | FAERS: 2 | US FAERS | |
| 2 | Acute kidney injury | FAERS: 1 | US FAERS | |
| 3 | Alanine Aminotransferase Increased | FAERS: 1 | US FAERS | |
| 4 | Arthralgia | FAERS: 1 | US FAERS | |
| 5 | Asthenia | FAERS: 1 | US FAERS | |
| 6 | Dizziness | FAERS: 1 | US FAERS | |
| 7 | Gastrointestinal toxicity | FAERS: 1 | US FAERS | |
| 8 | Headache | FAERS: 1 | US FAERS | |
| 9 | Hepatotoxicity | FAERS: 1 | US FAERS | |
| 10 | Lipodystrophy acquired | FAERS: 1 | US FAERS | |
| 11 | Lipohypertrophy | FAERS: 1 | US FAERS | |
| 12 | Maternal exposure during breast feeding | FAERS: 1 | US FAERS | |
| 13 | Neutropenia | FAERS: 1 | US FAERS | |
| 14 | Transaminases increased | FAERS: 1 | US FAERS | |
| 15 | Virologic failure | FAERS: 1 | US FAERS |
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