EC145
(KUZYSQSABONDME-QRLOMCMNSA-N)
Structure
- SMILES
- COc1cc2N(C)[C@@H]3[C@@]4(c2cc1[C@]1(C[C@H]2CN(CCc5c1[nH]c1c5cccc1)C[C@](C2)(O)CC)C(=O)OC)CCN1[C@H]4[C@@]([C@H]([C@]3(O)C(=O)NNC(=O)OCCSSC[C@@H](C(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CC[C@@H](C(=O)O)NC(=O)c2ccc(cc2)NCc2cnc3c(n2)c(=O)nc([nH]3)N)CC(=O)O)CCCNC(=N)N)CC(=O)O)CC(=O)O)O)(CC)C=CC1
- Type(s)
- Investigational
- ATC code(s)
- L01CA06
- Molecular Formula:
- C86H109N21O26S2
- Molecular Weight:
- 1917.040
- Log P:
- 3.3792
- Hydrogen Bond Acceptor:
- 47
- Hydrogen Bond Donor:
- 23
- TPSA:
- 772.34
- CAS Number(s):
- 742092-03-1
Synonym(s)
1.
EC145
2.
vintafolide
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Constipation | 19837906 | CTD | |
| 2 | Neoplasms | 17483358 | CTD | |
| 3 | Peripheral Nervous System Diseases | 19837906 | CTD |
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