methylnaltrexone
(JVLBPIPGETUEET-GAAHOAFPSA-O)
Structure
- SMILES
- O=C1CC[C@@]2([C@@]34[C@H]1Oc1c4c(C[C@H]2[N+](CC3)(C)CC2CC2)ccc1O)O
- Molecular Formula:
- C21H26NO4+
- Molecular Weight:
- 356.435
- Log P:
- 1.6288
- Hydrogen Bond Acceptor:
- 4
- Hydrogen Bond Donor:
- 2
- TPSA:
- 66.76
- CAS Number(s):
- 73232-52-7; 83387-25-1
Synonym(s)
1.
methylnaltrexone
2.
(5alpha)-17-(cyclopropylmethyl)-3,14-dihydroxy-17-methyl-4,5-epoxymorphinan-17-ium-6-one
3.
17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinanium-6-one
4.
MRZ 2663BR
5.
MRZ-2663
6.
N-methylnaltrexone bromide
7.
Relistor
8.
methyl-naltrexone hydrobromide
9.
methylnaltrexone bromide
10.
morphinan-17-ium-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-, (5alpha)-
11.
morphinan-17-ium-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-, bromide, (5alpha,17R)-
12.
morphinanium, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-6-oxo-, (5alpha)-
13.
naltrexone MB
14.
naltrexone methobromide
15.
naltrexone methylbromide
16.
naltrexonium methiodide
17.
quaternary ammonium naltrexone
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Chills | FAERS: 2 | US FAERS | |
| 2 | Intestinal Perforation | FAERS: 2 | US FAERS | |
| 3 | Abdominal Pain | FAERS: 1 | SIDER US FAERS | |
| 4 | Asthenia | FAERS: 1 | US FAERS | |
| 5 | Drug withdrawal syndrome | FAERS: 1 | US FAERS | |
| 6 | Intestinal Obstruction | FAERS: 1 | US FAERS | |
| 7 | Large intestine perforation | FAERS: 1 | US FAERS | |
| 8 | Nausea | FAERS: 1 | SIDER US FAERS | |
| 9 | Retroperitoneal infection | FAERS: 1 | US FAERS | |
| 10 | Tachycardia | FAERS: 1 | US FAERS | |
| 11 | Vomiting | FAERS: 1 | SIDER US FAERS | |
| 12 | Catalepsy | 6682490 | CTD | |
| 13 | Dizziness | SIDER | ||
| 14 | Erythema | SIDER | ||
| 15 | Flatulence | SIDER | ||
| 16 | Gastrointestinal Pain | SIDER | ||
| 17 | Gastrointestinal perforation | SIDER | ||
| 18 | Injection Site Reaction | SIDER | ||
| 19 | Pain | SIDER | ||
| 20 | Redness | SIDER | ||
| 21 | nervous system disorder | SIDER |
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