MetaADEDB 2.0 @ LMMD
sofalcone
(GFWRVVCDTLRWPK-KPKJPENVSA-N)
Structure
SMILES
OC(=O)COc1cc(OCC=C(C)C)ccc1C(=O)/C=C/c1ccc(cc1)OCC=C(C)C
Type(s)
Investigational
Molecular Formula:
C27H30O6
Molecular Weight:
450.523
Log P:
5.7361
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
1
TPSA:
82.06
CAS Number(s):
64506-49-6; 153175-87-2
Synonym(s)
1.
sofalcone
2.
2-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy)chalcone
3.
SU 88
4.
SU-88
5.
Solon
External Link(s)
MeSHC035032
PubChem Compound5282219
ChEBI135732
CHEMBLCHEMBL1441961
DrugBankDB05197
DrugCentral2456
KEGGdr:D01956
Therapeutic Target DatabaseD06BLQ
ZINC3831462
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AcidosisOFFSIDES
2Acute prerenal failureOFFSIDES
3Alanine Aminotransferase IncreasedOFFSIDES
4AnhidrosisOFFSIDES
5ApathyOFFSIDES
6AppendicitisOFFSIDES
7AutomatismOFFSIDES
8Bacteria stool identifiedOFFSIDES
9Blood alkaline phosphatase increasedOFFSIDES
10Blood amylase increasedOFFSIDES
11Blood bilirubin unconjugated increasedOFFSIDES
12Blood creatinine increasedOFFSIDES
13Blood elastase increasedOFFSIDES
14Blood urea increasedOFFSIDES
15BradycardiaOFFSIDES
16Brain ContusionOFFSIDES
17CholangiolitisOFFSIDES
18Clostridium colitisOFFSIDES
19Cold sweatOFFSIDES
20Device related infectionOFFSIDES
21Disseminated Intravascular CoagulationOFFSIDES
22Duodenal UlcerOFFSIDES
23ExcoriationOFFSIDES
24Gastric mucosal lesionOFFSIDES
25GastroenteritisOFFSIDES
26GlobulinuriaOFFSIDES
27GoutOFFSIDES
28HydrocephalusOFFSIDES
29Kidney FailureOFFSIDES
30Large intestine perforationOFFSIDES
31LipaseOFFSIDES
32Lymphocyte stimulation test positiveOFFSIDES
33Metabolic acidosisOFFSIDES
34Muscle WeaknessOFFSIDES
35Musculoskeletal stiffnessOFFSIDES
36NasopharyngitisOFFSIDES
37NephrolithiasisOFFSIDES
38Nephrotic SyndromeOFFSIDES
39PROTHROMBIN TIMEOFFSIDES
40PeriarthritisOFFSIDES
41PeritonitisOFFSIDES
42Pneumocystis jiroveci pneumoniaOFFSIDES
43Prothrombin level decreasedOFFSIDES
44Pulmonary HypertensionOFFSIDES
45PyelonephritisOFFSIDES
46QuadriplegiaOFFSIDES
47Ruptured cerebral aneurysmOFFSIDES
48Septic ShockOFFSIDES
49Stevens-Johnson SyndromeOFFSIDES
50VasospasmOFFSIDES
51Vertebral artery occlusionOFFSIDES
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