MetaADEDB 2.0 @ LMMD
lesinurad
(FGQFOYHRJSUHMR-UHFFFAOYSA-N)
Structure
SMILES
OC(=O)CSc1nnc(n1c1ccc(c2c1cccc2)C1CC1)Br
Type(s)
Approved; Investigational
ATC code(s)
M04AB05
Molecular Formula:
C17H14BrN3O2S
Molecular Weight:
404.281
Log P:
4.2371
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
1
TPSA:
93.31
CAS Number(s):
878672-00-5
Synonym(s)
1.
lesinurad
2.
((5-bromo-4-(4-cyclopropyl-1-naphthyl)-4H-1,2,4-triazol-3-yl)sulfanyl)acetic acid
3.
RDEA594
4.
Zurampic
External Link(s)
MeSHC000593471
PubChem Compound53465279
BindingDB37953
ChEBI90929
CHEMBLCHEMBL2105720
DrugBankDB11560
DrugCentral5075
IUPHAR/BPS Guide to PHARMACOLOGY7673
KEGGdr:D09921
Therapeutic Target DatabaseD0C3SW
ZINC84757007
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Blood creatinine increasedFAERS: 2US FAERS
2Product use in unapproved indicationFAERS: 2US FAERS
3Abdominal PainFAERS: 1US FAERS
4Blood creatinine decreasedFAERS: 1US FAERS
5Chest PainFAERS: 1US FAERS
6Cold sweatFAERS: 1US FAERS
7DehydrationFAERS: 1US FAERS
8DizzinessFAERS: 1US FAERS
9FatigueFAERS: 1US FAERS
10HeadacheFAERS: 1US FAERS
11Limb discomfortFAERS: 1US FAERS
12MalaiseFAERS: 1US FAERS
13Myocardial InfarctionFAERS: 1US FAERS
14PalpitationsFAERS: 1US FAERS
15Product packaging confusionFAERS: 1US FAERS
16Product use issueFAERS: 1US FAERS
17VomitingFAERS: 1US FAERS
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