lonafarnib
(DHMTURDWPRKSOA-RUZDIDTESA-N)
Structure
- SMILES
- Clc1cc(Br)c2c(c1)CCc1c([C@@H]2C2CCN(CC2)C(=O)CC2CCN(CC2)C(=O)N)ncc(c1)Br
- Type(s)
- Investigational
- Molecular Formula:
- C27H31Br2ClN4O2
- Molecular Weight:
- 638.822
- Log P:
- 6.4860
- Hydrogen Bond Acceptor:
- 6
- Hydrogen Bond Donor:
- 1
- TPSA:
- 79.53
- CAS Number(s):
- 193275-84-2; 193275-86-4
Synonym(s)
1.
lonafarnib
2.
(+)4-(2-(4-(8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-yl)-1-piperidinyl)-2-oxoethyl)-1-piperidinecarboxamide
3.
4-(2-(4-(8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo-(5,6)-cyclohepta(1,2-b)-pyridin-11(R)-yl)-1-piperidinyl)-2-oxo-ethyl)-1-piperidinecarboxamide
4.
SCH 66336
5.
SCH66336
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Malignant neoplasm progression | FAERS: 1 | US FAERS | |
| 2 | Diarrhea | 15131032 | CTD | |
| 3 | Hyperbilirubinemia | 15131032 | CTD | |
| 4 | Multiple Myeloma | 16118318 16996129 | CTD | |
| 5 | Neutropenia | 15131032 | CTD |
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