Encorafenib
(CMJCXYNUCSMDBY-ZDUSSCGKSA-N)
Structure
- SMILES
- COC(=O)N[C@H](CNc1nccc(n1)c1cn(nc1c1cc(Cl)cc(c1F)NS(=O)(=O)C)C(C)C)C
- Type(s)
- Approved; Investigational
- ATC code(s)
- L01XE46
- Molecular Formula:
- C22H27ClFN7O4S
- Molecular Weight:
- 540.011
- Log P:
- 5.5261
- Hydrogen Bond Acceptor:
- 11
- Hydrogen Bond Donor:
- 3
- TPSA:
- 148.51
- CAS Number(s):
- 1269440-17-6
Synonym(s)
1.
Encorafenib
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Product use in unapproved indication | FAERS: 5 | US FAERS | |
| 2 | Vomiting | FAERS: 2 | US FAERS | |
| 3 | Amnesia | FAERS: 1 | US FAERS | |
| 4 | Encephalitis | FAERS: 1 | US FAERS | |
| 5 | Flushing | FAERS: 1 | US FAERS | |
| 6 | Muscle tightness | FAERS: 1 | US FAERS | |
| 7 | Nausea | FAERS: 1 | US FAERS | |
| 8 | Occupational exposure to product | FAERS: 1 | US FAERS | |
| 9 | Pain | FAERS: 1 | US FAERS | |
| 10 | Pancreatitis | FAERS: 1 | US FAERS | |
| 11 | Product use complaint | FAERS: 1 | US FAERS | |
| 12 | Skin toxicity | FAERS: 1 | US FAERS | |
| 13 | Urticaria | FAERS: 1 | US FAERS |
Powered by :
Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120240
Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.