AM 251
(BUZAJRPLUGXRAB-UHFFFAOYSA-N)
Structure
- SMILES
- Ic1ccc(cc1)c1c(C)c(nn1c1ccc(cc1Cl)Cl)C(=O)NN1CCCCC1
- Molecular Formula:
- C22H21Cl2IN4O
- Molecular Weight:
- 555.239
- Log P:
- 6.2186
- Hydrogen Bond Acceptor:
- 5
- Hydrogen Bond Donor:
- 1
- TPSA:
- 50.16
- CAS Number(s):
- 183232-66-8
Synonym(s)
1.
AM 251
2.
AM-251
3.
AM251
4.
N-(piperidin-1-yl)-1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxamide
5.
N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
External Link(s)
| MeSH | C103505 |
| PubChem Compound | 2125 |
| BindingDB | 21279 |
| ChEBI | 90724 |
| CHEMBL | CHEMBL285932 |
| IUPHAR/BPS Guide to PHARMACOLOGY | 3317 |
| KEGG | cpd:C20220 |
| Therapeutic Target Database | D08YQT |
| ZINC | 1997139 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Amphetamine-Related Disorders | 12095072 | CTD | |
| 2 | Cocaine-Related Disorders | 16914679 17596442 | CTD | |
| 3 | Dyskinesia, Drug-Induced | 25447325 | CTD | |
| 4 | Nerve Degeneration | 24211273 | CTD | |
| 5 | Organophosphate poisoning | 25447325 | CTD | |
| 6 | Pain | 18987195 | CTD | |
| 7 | Seizures | 29042214 | CTD | |
| 8 | Substance Withdrawal Syndrome | 21324836 | CTD |
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