MetaADEDB 2.0 @ LMMD
clindamycin phosphate benzoyl peroxide combination
(APQDBWGZCQHKHQ-SHSUDHJHSA-N)
Structure
SMILES
O=C(c1ccccc1)OOC(=O)c1ccccc1.CCC[C@H]1CN([C@@H](C1)C(=O)N[C@@H]([C@H]1O[C@H](SC)[C@@H]([C@H]([C@H]1O)O)OP(=O)(O)O)[C@@H](Cl)C)C
Molecular Formula:
C32H44ClN2O12PS
Molecular Weight:
747.190
Log P:
3.4507
Hydrogen Bond Acceptor:
15
Hydrogen Bond Donor:
5
TPSA:
236.5
CAS Number(s):
N/A
Synonym(s)
1.
clindamycin phosphate benzoyl peroxide combination
2.
BenzaClin
3.
Duac gel
4.
benzoyl peroxide clindamycin phosphate combination
5.
benzoyl peroxide, clindamycin drug combination
6.
clindoxyl
7.
clindoxyl gel
External Link(s)
MeSHC466951
PubChem Compound57383951
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 12
Canada Vigilance: 4
Canada Vigilance
US FAERS
2ErythemaFAERS: 12
Canada Vigilance: 2
Canada Vigilance
US FAERS
3Product quality issueFAERS: 8
Canada Vigilance: 2
Canada Vigilance
US FAERS
4Application site erythemaFAERS: 7US FAERS
5Expired product administeredFAERS: 7US FAERS
6AcneFAERS: 6
Canada Vigilance: 2
Canada Vigilance
US FAERS
7Application site painFAERS: 5US FAERS
8Application site pruritusFAERS: 5US FAERS
9Application site swellingFAERS: 5US FAERS
10No adverse eventFAERS: 5US FAERS
11PruritusFAERS: 4
Canada Vigilance: 2
Canada Vigilance
US FAERS
12Application site irritationFAERS: 3US FAERS
13Dry skinFAERS: 3US FAERS
14Accidental exposure to productFAERS: 2US FAERS
15Application site drynessFAERS: 2US FAERS
16Contraindicated product administeredFAERS: 2US FAERS
17HypersensitivityFAERS: 2US FAERS
18Rash erythematousFAERS: 2US FAERS
19Skin reactionFAERS: 2US FAERS
20effusionFAERS: 2US FAERS
21AngioedemaFAERS: 1US FAERS
22Application site erosionFAERS: 1US FAERS
23Application site maculeFAERS: 1US FAERS
24Application site rashFAERS: 1US FAERS
25Application site reactionFAERS: 1US FAERS
26Application site warmthFAERS: 1US FAERS
27Burning sensationFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
28ColitisFAERS: 1US FAERS
29Drug ineffective for unapproved indicationFAERS: 1US FAERS
30Exfoliative rashFAERS: 1US FAERS
31Incorrect product storageFAERS: 1US FAERS
32LymphadenopathyFAERS: 1US FAERS
33MiliariaFAERS: 1US FAERS
34NauseaFAERS: 1US FAERS
35Oropharyngeal blisteringFAERS: 1US FAERS
36Oropharyngeal painFAERS: 1US FAERS
37Pain of skinFAERS: 1US FAERS
38PapuleFAERS: 1US FAERS
39Product depositFAERS: 1US FAERS
40Product use issueFAERS: 1US FAERS
41Pulmonary EmbolismFAERS: 1US FAERS
42Skin irritationFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
43SwellingFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
44Tongue blisteringFAERS: 1US FAERS
45Weight decreasedFAERS: 1US FAERS
46Therapeutic product effect decreasedCanada Vigilance: 1Canada Vigilance
47UrticariaCanada Vigilance: 2Canada Vigilance
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