"Compound ID"	"Compound name"	"Original SMILES"	"Prepared SMILES"	"Target ID"	"Protein name"	"Protein family"	"Gene symbol"	"Gene ID"	Organism	Score	Rank
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P00734	"Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain]"	"Peptidase S1 family"	F2	2147;	"Homo sapiens (Human)"	3.84752	1
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P41595	"5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)"	"G-protein coupled receptor 1 family"	HTR2B	3357;	"Homo sapiens (Human)"	3.67108	2
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P49286	"Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)"	"G-protein coupled receptor 1 family"	MTNR1B	4544;	"Homo sapiens (Human)"	3.49278	3
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P08908	"5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)"	"G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamily"	HTR1A	3350;	"Homo sapiens (Human)"	3.4704	4
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P28223	"5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)"	"G-protein coupled receptor 1 family"	HTR2A	3356;	"Homo sapiens (Human)"	3.3189	5
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P48039	"Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)"	"G-protein coupled receptor 1 family"	MTNR1A	4543;	"Homo sapiens (Human)"	3.22421	6
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P27487	"Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)]"	"Peptidase S9B family, DPPIV subfamily"	DPP4	1803;	"Homo sapiens (Human)"	3.07118	7
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P14416	"D(2) dopamine receptor (Dopamine D2 receptor)"	"G-protein coupled receptor 1 family"	DRD2	1813;	"Homo sapiens (Human)"	3.05121	8
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P50406	"5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)"	"G-protein coupled receptor 1 family"	HTR6	3362;	"Homo sapiens (Human)"	3.01278	9
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P25103	"Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1)"	"G-protein coupled receptor 1 family"	TACR1	6869;	"Homo sapiens (Human)"	2.9455	10
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	Q13547	"Histone deacetylase 1 (HD1) (EC 3.5.1.98)"	"Histone deacetylase family, HD type 1 subfamily"	HDAC1	3065;	"Homo sapiens (Human)"	2.88433	11
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P28221	"5-hydroxytryptamine receptor 1D (5-HT-1D) (5-HT1D) (Serotonin 1D alpha receptor) (5-HT-1D-alpha) (Serotonin receptor 1D)"	"G-protein coupled receptor 1 family"	HTR1D	3352;	"Homo sapiens (Human)"	2.84335	12
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P35462	"D(3) dopamine receptor (Dopamine D3 receptor)"	"G-protein coupled receptor 1 family"	DRD3	1814;	"Homo sapiens (Human)"	2.78929	13
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P41145	"Kappa-type opioid receptor (K-OR-1) (KOR-1)"	"G-protein coupled receptor 1 family"	OPRK1	4986;	"Homo sapiens (Human)"	2.72485	14
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P08253	"72 kDa type IV collagenase (EC 3.4.24.24) (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) (TBE-1) [Cleaved into: PEX]"	"Peptidase M10A family"	MMP2	4313;	"Homo sapiens (Human)"	2.62553	15
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P32239	"Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R)"	"G-protein coupled receptor 1 family"	CCKBR	887;	"Homo sapiens (Human)"	2.5235	16
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P28222	"5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (S12) (Serotonin 1D beta receptor) (5-HT-1D-beta) (Serotonin receptor 1B)"	"G-protein coupled receptor 1 family"	HTR1B	3351;	"Homo sapiens (Human)"	2.24326	17
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P03956	"Interstitial collagenase (EC 3.4.24.7) (Fibroblast collagenase) (Matrix metalloproteinase-1) (MMP-1) [Cleaved into: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase]"	"Peptidase M10A family"	MMP1	4312;	"Homo sapiens (Human)"	2.23062	18
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P28335	"5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)"	"G-protein coupled receptor 1 family"	HTR2C	3358;	"Homo sapiens (Human)"	2.21363	19
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P31645	"Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)"	"Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamily"	SLC6A4	6532;	"Homo sapiens (Human)"	2.20035	20
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P08254	"Stromelysin-1 (SL-1) (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1)"	"Peptidase M10A family"	MMP3	4314;	"Homo sapiens (Human)"	2.11217	21
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	Q9Y5N1	"Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)"	"G-protein coupled receptor 1 family"	HRH3	11255;	"Homo sapiens (Human)"	2.07193	22
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P35372	"Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)"	"G-protein coupled receptor 1 family"	OPRM1	4988;	"Homo sapiens (Human)"	2.06011	23
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P06756	"Integrin alpha-V (Vitronectin receptor) (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain]"	"Integrin alpha chain family"	ITGAV	3685;	"Homo sapiens (Human)"	2.00616	24
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P22894	"Neutrophil collagenase (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (PMNL collagenase) (PMNL-CL)"	"Peptidase M10A family"	MMP8	4317;	"Homo sapiens (Human)"	1.96174	25
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P00918	"Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)"	"Alpha-carbonic anhydrase family"	CA2	760;	"Homo sapiens (Human)"	1.94752	26
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P21917	"D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)"	"G-protein coupled receptor 1 family"	DRD4	1815;	"Homo sapiens (Human)"	1.91692	27
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P00797	"Renin (EC 3.4.23.15) (Angiotensinogenase)"	"Peptidase A1 family"	REN	5972;	"Homo sapiens (Human)"	1.8912	28
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P08913	"Alpha-2A adrenergic receptor (Alpha-2 adrenergic receptor subtype C10) (Alpha-2A adrenoreceptor) (Alpha-2A adrenoceptor) (Alpha-2AAR)"	"G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA2A sub-subfamily"	ADRA2A	150;	"Homo sapiens (Human)"	1.88711	29
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P61073	"C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (FB22) (Fusin) (HM89) (LCR1) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (Lipopolysaccharide-associated protein 3) (LAP-3) (LPS-associated protein 3) (NPYRL) (Stromal cell-derived factor 1 receptor) (SDF-1 receptor) (CD antigen CD184)"	"G-protein coupled receptor 1 family"	CXCR4	7852;	"Homo sapiens (Human)"	1.86693	30
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P07477	"Trypsin-1 (EC 3.4.21.4) (Beta-trypsin) (Cationic trypsinogen) (Serine protease 1) (Trypsin I) [Cleaved into: Alpha-trypsin chain 1; Alpha-trypsin chain 2]"	"Peptidase S1 family"	PRSS1	5644;	"Homo sapiens (Human)"	1.80456	31
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P14780	"Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB) [Cleaved into: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9]"	"Peptidase M10A family"	MMP9	4318;	"Homo sapiens (Human)"	1.74461	32
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P30939	"5-hydroxytryptamine receptor 1F (5-HT-1F) (5-HT1F) (Serotonin receptor 1F)"	"G-protein coupled receptor 1 family"	HTR1F	3355;	"Homo sapiens (Human)"	1.73567	33
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P09237	"Matrilysin (EC 3.4.24.23) (Matrin) (Matrix metalloproteinase-7) (MMP-7) (Pump-1 protease) (Uterine metalloproteinase)"	"Peptidase M10A family"	MMP7	4316;	"Homo sapiens (Human)"	1.70986	34
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P28074	"Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit MB1) (Proteasome subunit X)"	"Peptidase T1B family"	PSMB5	5693;	"Homo sapiens (Human)"	1.69066	35
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P34969	"5-hydroxytryptamine receptor 7 (5-HT-7) (5-HT7) (5-HT-X) (Serotonin receptor 7)"	"G-protein coupled receptor 1 family"	HTR7	3363;	"Homo sapiens (Human)"	1.62825	36
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P25101	"Endothelin-1 receptor (Endothelin receptor type A) (ET-A) (ETA-R) (hET-AR)"	"G-protein coupled receptor 1 family, Endothelin receptor subfamily, EDNRA sub-subfamily"	EDNRA	1909;	"Homo sapiens (Human)"	1.60275	37
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P18089	"Alpha-2B adrenergic receptor (Alpha-2 adrenergic receptor subtype C2) (Alpha-2B adrenoreceptor) (Alpha-2B adrenoceptor) (Alpha-2BAR)"	"G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA2B sub-subfamily"	ADRA2B	151;	"Homo sapiens (Human)"	1.59911	38
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P56524	"Histone deacetylase 4 (HD4) (EC 3.5.1.98)"	"Histone deacetylase family, HD type 2 subfamily"	HDAC4	9759;	"Homo sapiens (Human)"	1.54257	39
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P43166	"Carbonic anhydrase 7 (EC 4.2.1.1) (Carbonate dehydratase VII) (Carbonic anhydrase VII) (CA-VII)"	"Alpha-carbonic anhydrase family"	CA7	766;	"Homo sapiens (Human)"	1.53862	40
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	O43570	"Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)"	"Alpha-carbonic anhydrase family"	CA12	771;	"Homo sapiens (Human)"	1.53597	41
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	Q92847	"Growth hormone secretagogue receptor type 1 (GHS-R) (GH-releasing peptide receptor) (GHRP) (Ghrelin receptor)"	"G-protein coupled receptor 1 family"	GHSR	2693;	"Homo sapiens (Human)"	1.53053	42
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P14625	"Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Tumor rejection antigen 1) (gp96 homolog)"	"Heat shock protein 90 family"	HSP90B1	7184;	"Homo sapiens (Human)"	1.51723	43
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P09874	"Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-)"		PARP1	142;	"Homo sapiens (Human)"	1.51316	44
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P12931	"Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)"	"Protein kinase superfamily, Tyr protein kinase family, SRC subfamily"	SRC	6714;	"Homo sapiens (Human)"	1.51073	45
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P35968	"Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)"	"Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily"	KDR	3791;	"Homo sapiens (Human)"	1.51014	46
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P03372	"Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)"	"Nuclear hormone receptor family, NR3 subfamily"	ESR1	2099;	"Homo sapiens (Human)"	1.47615	47
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P23141	"Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) (Carboxylesterase 1) (CE-1) (hCE-1) (EC 3.1.1.1) (Cocaine carboxylesterase) (Egasyn) (HMSE) (Methylumbelliferyl-acetate deacetylase 1) (EC 3.1.1.56) (Monocyte/macrophage serine esterase) (Retinyl ester hydrolase) (REH) (Serine esterase 1) (Triacylglycerol hydrolase) (TGH)"	"Type-B carboxylesterase/lipase family"	CES1	1066;	"Homo sapiens (Human)"	1.45001	48
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P45452	"Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13)"	"Peptidase M10A family"	MMP13	4322;	"Homo sapiens (Human)"	1.44834	49
1	Untitled	[H]c1c([H])c([H])c(C([H])([H])[C@]2([H])C(=O)N3[C@@]4([H])N([H])c5c([H])c([H])c([H])c([H])c5[C@@]4(c4c([H])c([H])c([H])c5c(C([H])([H])[C@]6([H])C(=O)N([H])[C@]([H])(C([H])([H])c7c([H])c([H])c([H])c([H])c7[H])C(=O)N6[H])c([H])n([H])c45)C([H])([H])[C@@]3([H])C(=O)N2[H])c([H])c1[H]	O=C1N[C@H](Cc2ccccc2)C(=O)N[C@@H]1Cc1c[nH]c2c1cccc2[C@]12C[C@@H]3N([C@H]1Nc1c2cccc1)C(=O)[C@H](NC3=O)Cc1ccccc1	P18825	"Alpha-2C adrenergic receptor (Alpha-2 adrenergic receptor subtype C4) (Alpha-2C adrenoreceptor) (Alpha-2C adrenoceptor) (Alpha-2CAR)"	"G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA2C sub-subfamily"	ADRA2C	152;	"Homo sapiens (Human)"	1.43796	50