"Compound ID" "Compound name" "Original SMILES" "Prepared SMILES" "Target ID" "Protein name" "Protein family" "Gene symbol" "Gene ID" Organism Score Rank 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P05067 "Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta A4 protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]" "APP family" APP 351; "Homo sapiens (Human)" 3.4995 1 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C Q92731 "Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)" "Nuclear hormone receptor family, NR3 subfamily" ESR2 2100; "Homo sapiens (Human)" 3.44238 2 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 2.77507 3 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C Q99705 "Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein coupled receptor 24) (MCH-1R) (MCH1R) (MCHR) (SLC-1) (Somatostatin receptor-like protein)" "G-protein coupled receptor 1 family" MCHR1 2847; "Homo sapiens (Human)" 2.6523 4 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P11511 "Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase)" "Cytochrome P450 family" CYP19A1 1588; "Homo sapiens (Human)" 2.62187 5 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P15538 "Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase) (EC 1.14.15.4)" "Cytochrome P450 family" CYP11B1 1584; "Homo sapiens (Human)" 2.37095 6 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P03372 "Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)" "Nuclear hormone receptor family, NR3 subfamily" ESR1 2099; "Homo sapiens (Human)" 2.35551 7 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P01112 "GTPase HRas (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]" "Small GTPase superfamily, Ras family" HRAS 3265; "Homo sapiens (Human)" 2.31852 8 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 2.16537 9 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P34972 "Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)" "G-protein coupled receptor 1 family" CNR2 1269; "Homo sapiens (Human)" 2.11701 10 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P09960 "Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)" "Peptidase M1 family" LTA4H 4048; "Homo sapiens (Human)" 2.10761 11 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C Q8NER1 "Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)" "Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamily" TRPV1 7442; "Homo sapiens (Human)" 2.10335 12 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P23946 "Chymase (EC 3.4.21.39) (Alpha-chymase) (Mast cell protease I)" "Peptidase S1 family, Granzyme subfamily" CMA1 1215; "Homo sapiens (Human)" 2.02068 13 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C Q13547 "Histone deacetylase 1 (HD1) (EC 3.5.1.98)" "Histone deacetylase family, HD type 1 subfamily" HDAC1 3065; "Homo sapiens (Human)" 1.86224 14 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P13945 "Beta-3 adrenergic receptor (Beta-3 adrenoreceptor) (Beta-3 adrenoceptor)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB3 sub-subfamily" ADRB3 155; "Homo sapiens (Human)" 1.85898 15 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C Q9UBN7 "Histone deacetylase 6 (HD6) (EC 3.5.1.98)" "Histone deacetylase family, HD type 2 subfamily" HDAC6 10013; "Homo sapiens (Human)" 1.7232 16 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P34913 "Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]" "AB hydrolase superfamily, Epoxide hydrolase family" EPHX2 2053; "Homo sapiens (Human)" 1.67716 17 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.67225 18 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 1.51403 19 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P23141 "Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) (Carboxylesterase 1) (CE-1) (hCE-1) (EC 3.1.1.1) (Cocaine carboxylesterase) (Egasyn) (HMSE) (Methylumbelliferyl-acetate deacetylase 1) (EC 3.1.1.56) (Monocyte/macrophage serine esterase) (Retinyl ester hydrolase) (REH) (Serine esterase 1) (Triacylglycerol hydrolase) (TGH)" "Type-B carboxylesterase/lipase family" CES1 1066; "Homo sapiens (Human)" 1.44011 20 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.43295 21 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P52732 "Kinesin-like protein KIF11 (Kinesin-like protein 1) (Kinesin-like spindle protein HKSP) (Kinesin-related motor protein Eg5) (Thyroid receptor-interacting protein 5) (TR-interacting protein 5) (TRIP-5)" "TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, BimC subfamily" KIF11 3832; "Homo sapiens (Human)" 1.37847 22 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P22303 "Acetylcholinesterase (AChE) (EC 3.1.1.7)" "Type-B carboxylesterase/lipase family" ACHE 43; "Homo sapiens (Human)" 1.34476 23 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P49286 "Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)" "G-protein coupled receptor 1 family" MTNR1B 4544; "Homo sapiens (Human)" 1.30631 24 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 1.30225 25 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C Q02127 "Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase)" "Dihydroorotate dehydrogenase family, Type 2 subfamily" DHODH 1723; "Homo sapiens (Human)" 1.29222 26 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P0DMS8 "Adenosine receptor A3" "G-protein coupled receptor 1 family" ADORA3 140; "Homo sapiens (Human)" 1.26927 27 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P29371 "Neuromedin-K receptor (NKR) (NK-3 receptor) (NK-3R) (Neurokinin B receptor) (Tachykinin receptor 3)" "G-protein coupled receptor 1 family" TACR3 6870; "Homo sapiens (Human)" 1.26173 28 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C O15379 "Histone deacetylase 3 (HD3) (EC 3.5.1.98) (RPD3-2) (SMAP45)" "Histone deacetylase family, HD type 1 subfamily" HDAC3 8841; "Homo sapiens (Human)" 1.16354 29 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P08908 "5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)" "G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamily" HTR1A 3350; "Homo sapiens (Human)" 1.16341 30 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 1.14977 31 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P30542 "Adenosine receptor A1" "G-protein coupled receptor 1 family" ADORA1 134; "Homo sapiens (Human)" 1.14598 32 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P27338 "Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B)" "Flavin monoamine oxidase family" MAOB 4129; "Homo sapiens (Human)" 1.12508 33 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P42336 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)" "PI3/PI4-kinase family" PIK3CA 5290; "Homo sapiens (Human)" 1.09372 34 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P32239 "Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R)" "G-protein coupled receptor 1 family" CCKBR 887; "Homo sapiens (Human)" 1.08493 35 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P37231 "Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3)" "Nuclear hormone receptor family, NR1 subfamily" PPARG 5468; "Homo sapiens (Human)" 1.06562 36 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P29274 "Adenosine receptor A2a" "G-protein coupled receptor 1 family" ADORA2A 135; "Homo sapiens (Human)" 1.06394 37 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P21397 "Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A)" "Flavin monoamine oxidase family" MAOA 4128; "Homo sapiens (Human)" 1.0629 38 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P09874 "Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-)" PARP1 142; "Homo sapiens (Human)" 1.04058 39 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P43166 "Carbonic anhydrase 7 (EC 4.2.1.1) (Carbonate dehydratase VII) (Carbonic anhydrase VII) (CA-VII)" "Alpha-carbonic anhydrase family" CA7 766; "Homo sapiens (Human)" 1.03818 40 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C Q92769 "Histone deacetylase 2 (HD2) (EC 3.5.1.98)" "Histone deacetylase family, HD type 1 subfamily" HDAC2 3066; "Homo sapiens (Human)" 1.02824 41 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P48039 "Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)" "G-protein coupled receptor 1 family" MTNR1A 4543; "Homo sapiens (Human)" 1.02528 42 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P00742 "Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]" "Peptidase S1 family" F10 2159; "Homo sapiens (Human)" 1.01295 43 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C Q99835 "Smoothened homolog (SMO) (Protein Gx)" "G-protein coupled receptor Fz/Smo family" SMO 6608; "Homo sapiens (Human)" 0.967491 44 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P28335 "5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)" "G-protein coupled receptor 1 family" HTR2C 3358; "Homo sapiens (Human)" 0.966815 45 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P00374 "Dihydrofolate reductase (EC 1.5.1.3)" "Dihydrofolate reductase family" DHFR 1719; "Homo sapiens (Human)" 0.938826 46 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C O95271 "Poly [ADP-ribose] polymerase tankyrase-1 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (Poly [ADP-ribose] polymerase 5A) (Protein poly-ADP-ribosyltransferase tankyrase-1) (EC 2.4.2.-) (TNKS-1) (TRF1-interacting ankyrin-related ADP-ribose polymerase) (Tankyrase I) (Tankyrase-1) (TANK1)" TNKS 8658; "Homo sapiens (Human)" 0.934556 47 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P05177 "Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cholesterol 25-hydroxylase) (Cytochrome P(3)450) (Cytochrome P450 4) (Cytochrome P450-P3)" "Cytochrome P450 family" CYP1A2 1544; "Homo sapiens (Human)" 0.924552 48 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P15559 "NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Azoreductase) (DT-diaphorase) (DTD) (Menadione reductase) (NAD(P)H:quinone oxidoreductase 1) (Phylloquinone reductase) (Quinone reductase 1) (QR1)" "NAD(P)H dehydrogenase (quinone) family" NQO1 1728; "Homo sapiens (Human)" 0.904525 49 1 Untitled CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)NC=O O=CNc1cccc(c1)c1nc2c(o1)ccc(c2)C P21917 "D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)" "G-protein coupled receptor 1 family" DRD4 1815; "Homo sapiens (Human)" 0.896035 50 2 Untitled C(Cl)Cl ClCCl P25103 "Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1)" "G-protein coupled receptor 1 family" TACR1 6869; "Homo sapiens (Human)" 3.89526 1 2 Untitled C(Cl)Cl ClCCl P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 3.47952 2 2 Untitled C(Cl)Cl ClCCl P34972 "Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)" "G-protein coupled receptor 1 family" CNR2 1269; "Homo sapiens (Human)" 2.42027 3 2 Untitled C(Cl)Cl ClCCl Q92731 "Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)" "Nuclear hormone receptor family, NR3 subfamily" ESR2 2100; "Homo sapiens (Human)" 2.20313 4 2 Untitled C(Cl)Cl ClCCl P21917 "D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)" "G-protein coupled receptor 1 family" DRD4 1815; "Homo sapiens (Human)" 2.16654 5 2 Untitled C(Cl)Cl ClCCl Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 2.13316 6 2 Untitled C(Cl)Cl ClCCl P23141 "Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) (Carboxylesterase 1) (CE-1) (hCE-1) (EC 3.1.1.1) (Cocaine carboxylesterase) (Egasyn) (HMSE) (Methylumbelliferyl-acetate deacetylase 1) (EC 3.1.1.56) (Monocyte/macrophage serine esterase) (Retinyl ester hydrolase) (REH) (Serine esterase 1) (Triacylglycerol hydrolase) (TGH)" "Type-B carboxylesterase/lipase family" CES1 1066; "Homo sapiens (Human)" 2.09351 7 2 Untitled C(Cl)Cl ClCCl P48449 "Lanosterol synthase (EC 5.4.99.7) (2,3-epoxysqualene--lanosterol cyclase) (Oxidosqualene--lanosterol cyclase) (OSC) (hOSC)" "Terpene cyclase/mutase family" LSS 4047; "Homo sapiens (Human)" 2.06571 8 2 Untitled C(Cl)Cl ClCCl O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 2.02168 9 2 Untitled C(Cl)Cl ClCCl P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 2.01814 10 2 Untitled C(Cl)Cl ClCCl P10275 "Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)" "Nuclear hormone receptor family, NR3 subfamily" AR 367; "Homo sapiens (Human)" 2.01063 11 2 Untitled C(Cl)Cl ClCCl P48039 "Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)" "G-protein coupled receptor 1 family" MTNR1A 4543; "Homo sapiens (Human)" 1.96795 12 2 Untitled C(Cl)Cl ClCCl P34913 "Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]" "AB hydrolase superfamily, Epoxide hydrolase family" EPHX2 2053; "Homo sapiens (Human)" 1.95846 13 2 Untitled C(Cl)Cl ClCCl P41595 "5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)" "G-protein coupled receptor 1 family" HTR2B 3357; "Homo sapiens (Human)" 1.93749 14 2 Untitled C(Cl)Cl ClCCl O00748 "Cocaine esterase (EC 3.1.1.84) (Carboxylesterase 2) (CE-2) (hCE-2) (EC 3.1.1.1) (Methylumbelliferyl-acetate deacetylase 2) (EC 3.1.1.56)" "Type-B carboxylesterase/lipase family" CES2 8824; "Homo sapiens (Human)" 1.8451 15 2 Untitled C(Cl)Cl ClCCl P49286 "Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)" "G-protein coupled receptor 1 family" MTNR1B 4544; "Homo sapiens (Human)" 1.81023 16 2 Untitled C(Cl)Cl ClCCl P00918 "Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)" "Alpha-carbonic anhydrase family" CA2 760; "Homo sapiens (Human)" 1.79693 17 2 Untitled C(Cl)Cl ClCCl P21554 "Cannabinoid receptor 1 (CB-R) (CB1) (CANN6)" "G-protein coupled receptor 1 family" CNR1 1268; "Homo sapiens (Human)" 1.76414 18 2 Untitled C(Cl)Cl ClCCl Q14416 "Metabotropic glutamate receptor 2 (mGluR2)" "G-protein coupled receptor 3 family" GRM2 2912; "Homo sapiens (Human)" 1.73904 19 2 Untitled C(Cl)Cl ClCCl P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 1.72829 20 2 Untitled C(Cl)Cl ClCCl P30542 "Adenosine receptor A1" "G-protein coupled receptor 1 family" ADORA1 134; "Homo sapiens (Human)" 1.71895 21 2 Untitled C(Cl)Cl ClCCl Q8NER1 "Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)" "Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamily" TRPV1 7442; "Homo sapiens (Human)" 1.69268 22 2 Untitled C(Cl)Cl ClCCl Q99705 "Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein coupled receptor 24) (MCH-1R) (MCH1R) (MCHR) (SLC-1) (Somatostatin receptor-like protein)" "G-protein coupled receptor 1 family" MCHR1 2847; "Homo sapiens (Human)" 1.67076 23 2 Untitled C(Cl)Cl ClCCl P55055 "Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear receptor NER) (Nuclear receptor subfamily 1 group H member 2) (Ubiquitously-expressed nuclear receptor)" "Nuclear hormone receptor family, NR1 subfamily" NR1H2 7376; "Homo sapiens (Human)" 1.6496 24 2 Untitled C(Cl)Cl ClCCl Q03181 "Peroxisome proliferator-activated receptor delta (PPAR-delta) (NUCI) (Nuclear hormone receptor 1) (NUC1) (Nuclear receptor subfamily 1 group C member 2) (Peroxisome proliferator-activated receptor beta) (PPAR-beta)" "Nuclear hormone receptor family, NR1 subfamily" PPARD 5467; "Homo sapiens (Human)" 1.64695 25 2 Untitled C(Cl)Cl ClCCl P00915 "Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase B) (CAB) (Carbonic anhydrase I) (CA-I)" "Alpha-carbonic anhydrase family" CA1 759; "Homo sapiens (Human)" 1.60234 26 2 Untitled C(Cl)Cl ClCCl P04150 "Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)" "Nuclear hormone receptor family, NR3 subfamily" NR3C1 2908; "Homo sapiens (Human)" 1.58976 27 2 Untitled C(Cl)Cl ClCCl P31645 "Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)" "Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamily" SLC6A4 6532; "Homo sapiens (Human)" 1.58672 28 2 Untitled C(Cl)Cl ClCCl O75762 "Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120)" "Transient receptor (TC 1.A.4) family" TRPA1 8989; "Homo sapiens (Human)" 1.5821 29 2 Untitled C(Cl)Cl ClCCl Q9Y5Y4 "Prostaglandin D2 receptor 2 (Chemoattractant receptor-homologous molecule expressed on Th2 cells) (G-protein coupled receptor 44) (CD antigen CD294)" "G-protein coupled receptor 1 family" PTGDR2 11251; "Homo sapiens (Human)" 1.57567 30 2 Untitled C(Cl)Cl ClCCl Q13822 "Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2) (EC 3.1.4.39) (Autotaxin) (Extracellular lysophospholipase D) (LysoPLD)" "Nucleotide pyrophosphatase/phosphodiesterase family" ENPP2 5168; "Homo sapiens (Human)" 1.53799 31 2 Untitled C(Cl)Cl ClCCl P05067 "Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta A4 protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]" "APP family" APP 351; "Homo sapiens (Human)" 1.49702 32 2 Untitled C(Cl)Cl ClCCl O15554 "Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (SKCa 4) (SKCa4) (IKCa1) (IK1) (KCa3.1) (KCa4) (Putative Gardos channel)" "Potassium channel KCNN family, KCa3.1/KCNN4 subfamily" KCNN4 3783; "Homo sapiens (Human)" 1.49692 33 2 Untitled C(Cl)Cl ClCCl P28845 "Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC 1.1.1.146) (11-beta-hydroxysteroid dehydrogenase 1) (11-DH) (11-beta-HSD1) (Short chain dehydrogenase/reductase family 26C member 1)" "Short-chain dehydrogenases/reductases (SDR) family" HSD11B1 3290; "Homo sapiens (Human)" 1.48327 34 2 Untitled C(Cl)Cl ClCCl P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 1.47952 35 2 Untitled C(Cl)Cl ClCCl P05177 "Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cholesterol 25-hydroxylase) (Cytochrome P(3)450) (Cytochrome P450 4) (Cytochrome P450-P3)" "Cytochrome P450 family" CYP1A2 1544; "Homo sapiens (Human)" 1.44641 36 2 Untitled C(Cl)Cl ClCCl P49768 "Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]" "Peptidase A22A family" PSEN1 5663; "Homo sapiens (Human)" 1.44451 37 2 Untitled C(Cl)Cl ClCCl O60755 "Galanin receptor type 3 (GAL3-R) (GALR-3)" "G-protein coupled receptor 1 family" GALR3 8484; "Homo sapiens (Human)" 1.43705 38 2 Untitled C(Cl)Cl ClCCl P28335 "5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)" "G-protein coupled receptor 1 family" HTR2C 3358; "Homo sapiens (Human)" 1.43698 39 2 Untitled C(Cl)Cl ClCCl Q99720 "Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding protein) (SR-BP) (Sigma 1-type opioid receptor) (SIG-1R) (Sigma1-receptor) (Sigma1R) (hSigmaR1)" "ERG2 family" SIGMAR1 10280; "Homo sapiens (Human)" 1.42134 40 2 Untitled C(Cl)Cl ClCCl P27487 "Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)]" "Peptidase S9B family, DPPIV subfamily" DPP4 1803; "Homo sapiens (Human)" 1.40082 41 2 Untitled C(Cl)Cl ClCCl P08908 "5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)" "G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamily" HTR1A 3350; "Homo sapiens (Human)" 1.36525 42 2 Untitled C(Cl)Cl ClCCl P00748 "Coagulation factor XII (EC 3.4.21.38) (Hageman factor) (HAF) [Cleaved into: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Coagulation factor XIIa light chain (Beta-factor XIIa part 2)]" "Peptidase S1 family" F12 2161; "Homo sapiens (Human)" 1.3078 43 2 Untitled C(Cl)Cl ClCCl P28472 "Gamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3)" "Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRB3 sub-subfamily" GABRB3 2562; "Homo sapiens (Human)" 1.3006 44 2 Untitled C(Cl)Cl ClCCl P35367 "Histamine H1 receptor (H1R) (HH1R)" "G-protein coupled receptor 1 family" HRH1 3269; "Homo sapiens (Human)" 1.27535 45 2 Untitled C(Cl)Cl ClCCl P21453 "Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363)" "G-protein coupled receptor 1 family" S1PR1 1901; "Homo sapiens (Human)" 1.27522 46 2 Untitled C(Cl)Cl ClCCl P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.26483 47 2 Untitled C(Cl)Cl ClCCl Q02127 "Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase)" "Dihydroorotate dehydrogenase family, Type 2 subfamily" DHODH 1723; "Homo sapiens (Human)" 1.24108 48 2 Untitled C(Cl)Cl ClCCl P35228 "Nitric oxide synthase, inducible (EC 1.14.13.39) (Hepatocyte NOS) (HEP-NOS) (Inducible NO synthase) (Inducible NOS) (iNOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2)" "NOS family" NOS2 4843; "Homo sapiens (Human)" 1.21762 49 2 Untitled C(Cl)Cl ClCCl P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 1.21669 50 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P04278 "Sex hormone-binding globulin (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estradiol-binding globulin) (TeBG) (Testosterone-estrogen-binding globulin)" SHBG 6462; "Homo sapiens (Human)" 2.89854 1 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P10275 "Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)" "Nuclear hormone receptor family, NR3 subfamily" AR 367; "Homo sapiens (Human)" 2.85753 2 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 2.74102 3 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" O43570 "Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)" "Alpha-carbonic anhydrase family" CA12 771; "Homo sapiens (Human)" 2.71624 4 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 2.485 5 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" Q16853 "Membrane primary amine oxidase (EC 1.4.3.21) (Copper amine oxidase) (HPAO) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1)" "Copper/topaquinone oxidase family" AOC3 8639; "Homo sapiens (Human)" 2.30652 6 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" Q12882 "Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase)" "Dihydropyrimidine dehydrogenase family" DPYD 1806; "Homo sapiens (Human)" 2.23783 7 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" Q9ULX7 "Carbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase XIV) (CA-XIV)" "Alpha-carbonic anhydrase family" CA14 23632; "Homo sapiens (Human)" 2.11101 8 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P21554 "Cannabinoid receptor 1 (CB-R) (CB1) (CANN6)" "G-protein coupled receptor 1 family" CNR1 1268; "Homo sapiens (Human)" 2.09265 9 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P34913 "Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]" "AB hydrolase superfamily, Epoxide hydrolase family" EPHX2 2053; "Homo sapiens (Human)" 2.02278 10 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P06401 "Progesterone receptor (PR) (Nuclear receptor subfamily 3 group C member 3)" "Nuclear hormone receptor family, NR3 subfamily" PGR 5241; "Homo sapiens (Human)" 1.9991 11 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P04150 "Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)" "Nuclear hormone receptor family, NR3 subfamily" NR3C1 2908; "Homo sapiens (Human)" 1.99863 12 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P48449 "Lanosterol synthase (EC 5.4.99.7) (2,3-epoxysqualene--lanosterol cyclase) (Oxidosqualene--lanosterol cyclase) (OSC) (hOSC)" "Terpene cyclase/mutase family" LSS 4047; "Homo sapiens (Human)" 1.96067 13 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" O60733 "85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9)" PLA2G6 8398; "Homo sapiens (Human)" 1.85387 14 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P07339 "Cathepsin D (EC 3.4.23.5) [Cleaved into: Cathepsin D light chain; Cathepsin D heavy chain]" "Peptidase A1 family" CTSD 1509; "Homo sapiens (Human)" 1.85018 15 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P00918 "Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)" "Alpha-carbonic anhydrase family" CA2 760; "Homo sapiens (Human)" 1.79693 16 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P00915 "Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase B) (CAB) (Carbonic anhydrase I) (CA-I)" "Alpha-carbonic anhydrase family" CA1 759; "Homo sapiens (Human)" 1.78236 17 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" Q14534 "Squalene monooxygenase (EC 1.14.14.17) (Squalene epoxidase) (SE)" "Squalene monooxygenase family" SQLE 6713; "Homo sapiens (Human)" 1.70091 18 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P04183 "Thymidine kinase, cytosolic (EC 2.7.1.21)" "Thymidine kinase family" TK1 7083; "Homo sapiens (Human)" 1.68674 19 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" Q99720 "Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding protein) (SR-BP) (Sigma 1-type opioid receptor) (SIG-1R) (Sigma1-receptor) (Sigma1R) (hSigmaR1)" "ERG2 family" SIGMAR1 10280; "Homo sapiens (Human)" 1.64237 20 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P27338 "Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B)" "Flavin monoamine oxidase family" MAOB 4129; "Homo sapiens (Human)" 1.63555 21 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" Q13255 "Metabotropic glutamate receptor 1 (mGluR1)" "G-protein coupled receptor 3 family" GRM1 2911; "Homo sapiens (Human)" 1.54323 22 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P00352 "Retinal dehydrogenase 1 (RALDH 1) (RalDH1) (EC 1.2.1.-) (EC 1.2.1.36) (ALDH-E1) (ALHDII) (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic)" "Aldehyde dehydrogenase family" ALDH1A1 216; "Homo sapiens (Human)" 1.5355 23 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P04818 "Thymidylate synthase (TS) (TSase) (EC 2.1.1.45)" "Thymidylate synthase family" TYMS 7298; "Homo sapiens (Human)" 1.47985 24 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P23141 "Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) (Carboxylesterase 1) (CE-1) (hCE-1) (EC 3.1.1.1) (Cocaine carboxylesterase) (Egasyn) (HMSE) (Methylumbelliferyl-acetate deacetylase 1) (EC 3.1.1.56) (Monocyte/macrophage serine esterase) (Retinyl ester hydrolase) (REH) (Serine esterase 1) (Triacylglycerol hydrolase) (TGH)" "Type-B carboxylesterase/lipase family" CES1 1066; "Homo sapiens (Human)" 1.4232 25 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" O00748 "Cocaine esterase (EC 3.1.1.84) (Carboxylesterase 2) (CE-2) (hCE-2) (EC 3.1.1.1) (Methylumbelliferyl-acetate deacetylase 2) (EC 3.1.1.56)" "Type-B carboxylesterase/lipase family" CES2 8824; "Homo sapiens (Human)" 1.42011 26 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" Q9HCG7 "Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (Beta-glucocerebrosidase 2) (Beta-glucosidase 2) (Bile acid beta-glucosidase GBA2) (Bile acid glucosyl transferase GBA2) (Cholesterol glucosyltransferase GBA2) (EC 2.4.1.-) (Cholesteryl-beta-glucosidase GBA2) (EC 3.2.1.104) (Glucosylceramidase 2)" "Non-lysosomal glucosylceramidase family" GBA2 57704; "Homo sapiens (Human)" 1.40686 27 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 1.3867 28 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P25103 "Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1)" "G-protein coupled receptor 1 family" TACR1 6869; "Homo sapiens (Human)" 1.37726 29 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P00374 "Dihydrofolate reductase (EC 1.5.1.3)" "Dihydrofolate reductase family" DHFR 1719; "Homo sapiens (Human)" 1.35214 30 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" Q8NER1 "Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)" "Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamily" TRPV1 7442; "Homo sapiens (Human)" 1.32665 31 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P35354 "Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2)" "Prostaglandin G/H synthase family" PTGS2 5743; "Homo sapiens (Human)" 1.30654 32 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P41180 "Extracellular calcium-sensing receptor (CaR) (CaSR) (hCasR) (Parathyroid cell calcium-sensing receptor 1) (PCaR1)" "G-protein coupled receptor 3 family" CASR 846; "Homo sapiens (Human)" 1.2844 33 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" O75469 "Nuclear receptor subfamily 1 group I member 2 (Orphan nuclear receptor PAR1) (Orphan nuclear receptor PXR) (Pregnane X receptor) (Steroid and xenobiotic receptor) (SXR)" "Nuclear hormone receptor family, NR1 subfamily" NR1I2 8856; "Homo sapiens (Human)" 1.24425 34 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P21917 "D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)" "G-protein coupled receptor 1 family" DRD4 1815; "Homo sapiens (Human)" 1.23395 35 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P21397 "Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A)" "Flavin monoamine oxidase family" MAOA 4128; "Homo sapiens (Human)" 1.22374 36 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P43119 "Prostacyclin receptor (Prostaglandin I2 receptor) (PGI receptor) (PGI2 receptor) (Prostanoid IP receptor)" "G-protein coupled receptor 1 family" PTGIR 5739; "Homo sapiens (Human)" 1.21659 37 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P11511 "Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase)" "Cytochrome P450 family" CYP19A1 1588; "Homo sapiens (Human)" 1.2065 38 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P35372 "Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)" "G-protein coupled receptor 1 family" OPRM1 4988; "Homo sapiens (Human)" 1.16964 39 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P34972 "Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)" "G-protein coupled receptor 1 family" CNR2 1269; "Homo sapiens (Human)" 1.16494 40 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P09874 "Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-)" PARP1 142; "Homo sapiens (Human)" 1.15164 41 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P08246 "Neutrophil elastase (EC 3.4.21.37) (Bone marrow serine protease) (Elastase-2) (Human leukocyte elastase) (HLE) (Medullasin) (PMN elastase)" "Peptidase S1 family, Elastase subfamily" ELANE 1991; "Homo sapiens (Human)" 1.14901 42 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P41145 "Kappa-type opioid receptor (K-OR-1) (KOR-1)" "G-protein coupled receptor 1 family" OPRK1 4986; "Homo sapiens (Human)" 1.13973 43 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P37268 "Squalene synthase (SQS) (SS) (EC 2.5.1.21) (FPP:FPP farnesyltransferase) (Farnesyl-diphosphate farnesyltransferase)" "Phytoene/squalene synthase family" FDFT1 2222; "Homo sapiens (Human)" 1.12427 44 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P03372 "Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)" "Nuclear hormone receptor family, NR3 subfamily" ESR1 2099; "Homo sapiens (Human)" 1.10842 45 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" Q92731 "Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)" "Nuclear hormone receptor family, NR3 subfamily" ESR2 2100; "Homo sapiens (Human)" 1.10325 46 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 1.09788 47 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P05067 "Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta A4 protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]" "APP family" APP 351; "Homo sapiens (Human)" 1.07677 48 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P45452 "Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13)" "Peptidase M10A family" MMP13 4322; "Homo sapiens (Human)" 1.05748 49 3 Untitled "C#C/C=C\Cl" "Cl/C=C\C#C" P78536 "Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (Snake venom-like protease) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b)" ADAM17 6868; "Homo sapiens (Human)" 1.04407 50 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 Q9Y233 "cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17) (EC 3.1.4.35)" "Cyclic nucleotide phosphodiesterase family" PDE10A 10846; "Homo sapiens (Human)" 3.46167 1 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 Q92731 "Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)" "Nuclear hormone receptor family, NR3 subfamily" ESR2 2100; "Homo sapiens (Human)" 3.19081 2 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 3.06064 3 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P05067 "Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta A4 protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]" "APP family" APP 351; "Homo sapiens (Human)" 3.01783 4 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P34972 "Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)" "G-protein coupled receptor 1 family" CNR2 1269; "Homo sapiens (Human)" 2.78736 5 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P30542 "Adenosine receptor A1" "G-protein coupled receptor 1 family" ADORA1 134; "Homo sapiens (Human)" 2.78355 6 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P42229 "Signal transducer and activator of transcription 5A" "Transcription factor STAT family" STAT5A 6776; "Homo sapiens (Human)" 2.54139 7 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P15538 "Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase) (EC 1.14.15.4)" "Cytochrome P450 family" CYP11B1 1584; "Homo sapiens (Human)" 2.53518 8 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P15144 "Aminopeptidase N (AP-N) (hAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (Myeloid plasma membrane glycoprotein CD13) (gp150) (CD antigen CD13)" "Peptidase M1 family" ANPEP 290; "Homo sapiens (Human)" 2.38231 9 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 O00141 "Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK1 6446; "Homo sapiens (Human)" 2.37444 10 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P29274 "Adenosine receptor A2a" "G-protein coupled receptor 1 family" ADORA2A 135; "Homo sapiens (Human)" 2.29485 11 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 1.92117 12 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.89841 13 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P11511 "Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase)" "Cytochrome P450 family" CYP19A1 1588; "Homo sapiens (Human)" 1.75866 14 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 Q9NQS5 "G-protein coupled receptor 84 (Inflammation-related G-protein coupled receptor EX33)" "G-protein coupled receptor 1 family" GPR84 53831; "Homo sapiens (Human)" 1.74509 15 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 1.64694 16 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P27361 "Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK3 5595; "Homo sapiens (Human)" 1.63902 17 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P03372 "Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)" "Nuclear hormone receptor family, NR3 subfamily" ESR1 2099; "Homo sapiens (Human)" 1.63373 18 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.62774 19 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 1.57978 20 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P14061 "Estradiol 17-beta-dehydrogenase 1 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 1) (17-beta-HSD 1) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Placental 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 28C member 1)" "Short-chain dehydrogenases/reductases (SDR) family" HSD17B1 3292; "Homo sapiens (Human)" 1.50616 21 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P31645 "Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)" "Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamily" SLC6A4 6532; "Homo sapiens (Human)" 1.48042 22 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P28482 "Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK1 5594; "Homo sapiens (Human)" 1.3751 23 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 Q00535 "Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK5 1020; "Homo sapiens (Human)" 1.34776 24 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 1.32765 25 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P29275 "Adenosine receptor A2b" "G-protein coupled receptor 1 family" ADORA2B 136; "Homo sapiens (Human)" 1.31088 26 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 Q8IWQ3 "Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 2) (BR serine/threonine-protein kinase 2) (Serine/threonine-protein kinase 29) (Serine/threonine-protein kinase SAD-A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK2 9024; "Homo sapiens (Human)" 1.29425 27 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 Q96S37 "Solute carrier family 22 member 12 (Organic anion transporter 4-like protein) (Renal-specific transporter) (RST) (Urate anion exchanger 1)" "Major facilitator (TC 2.A.1) superfamily, Organic cation transporter (TC 2.A.1.19) family" SLC22A12 116085; "Homo sapiens (Human)" 1.21146 28 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P00374 "Dihydrofolate reductase (EC 1.5.1.3)" "Dihydrofolate reductase family" DHFR 1719; "Homo sapiens (Human)" 1.18249 29 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P37059 "Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239)" "Short-chain dehydrogenases/reductases (SDR) family" HSD17B2 3294; "Homo sapiens (Human)" 1.12569 30 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P10275 "Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)" "Nuclear hormone receptor family, NR3 subfamily" AR 367; "Homo sapiens (Human)" 1.11045 31 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P37231 "Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3)" "Nuclear hormone receptor family, NR1 subfamily" PPARG 5468; "Homo sapiens (Human)" 1.09136 32 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.09126 33 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P09874 "Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-)" PARP1 142; "Homo sapiens (Human)" 1.057 34 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P23141 "Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) (Carboxylesterase 1) (CE-1) (hCE-1) (EC 3.1.1.1) (Cocaine carboxylesterase) (Egasyn) (HMSE) (Methylumbelliferyl-acetate deacetylase 1) (EC 3.1.1.56) (Monocyte/macrophage serine esterase) (Retinyl ester hydrolase) (REH) (Serine esterase 1) (Triacylglycerol hydrolase) (TGH)" "Type-B carboxylesterase/lipase family" CES1 1066; "Homo sapiens (Human)" 1.05347 35 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P55263 "Adenosine kinase (AK) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase)" "Carbohydrate kinase PfkB family" ADK 132; "Homo sapiens (Human)" 1.03441 36 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 Q9BUB5 "MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK1 8569; "Homo sapiens (Human)" 1.02713 37 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 0.988753 38 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 Q9HBY8 "Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK2 10110; "Homo sapiens (Human)" 0.959096 39 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P27338 "Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B)" "Flavin monoamine oxidase family" MAOB 4129; "Homo sapiens (Human)" 0.952981 40 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P31749 "RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT1 207; "Homo sapiens (Human)" 0.952425 41 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P78527 "DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)" "PI3/PI4-kinase family" PRKDC 5591; "Homo sapiens (Human)" 0.940452 42 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 O43781 "Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1) (Regulatory erythroid kinase) (REDK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK3 8444; "Homo sapiens (Human)" 0.928768 43 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P29371 "Neuromedin-K receptor (NKR) (NK-3 receptor) (NK-3R) (Neurokinin B receptor) (Tachykinin receptor 3)" "G-protein coupled receptor 1 family" TACR3 6870; "Homo sapiens (Human)" 0.910619 44 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 Q13547 "Histone deacetylase 1 (HD1) (EC 3.5.1.98)" "Histone deacetylase family, HD type 1 subfamily" HDAC1 3065; "Homo sapiens (Human)" 0.897833 45 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P0DMS8 "Adenosine receptor A3" "G-protein coupled receptor 1 family" ADORA3 140; "Homo sapiens (Human)" 0.894677 46 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 Q8NER1 "Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)" "Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamily" TRPV1 7442; "Homo sapiens (Human)" 0.886246 47 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P19971 "Thymidine phosphorylase (TP) (EC 2.4.2.4) (Gliostatin) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (TdRPase)" "Thymidine/pyrimidine-nucleoside phosphorylase family" TYMP 1890; "Homo sapiens (Human)" 0.885155 48 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P50406 "5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)" "G-protein coupled receptor 1 family" HTR6 3362; "Homo sapiens (Human)" 0.872151 49 4 Untitled C1=CC=C(C=C1)C2=NC3=NNC(=C3C(=C2)C#N)N N#Cc1cc(nc2c1c(N)[nH]n2)c1ccccc1 P43235 "Cathepsin K (EC 3.4.22.38) (Cathepsin O) (Cathepsin O2) (Cathepsin X)" "Peptidase C1 family" CTSK 1513; "Homo sapiens (Human)" 0.866647 50