"Compound ID" "Compound name" "Original SMILES" "Prepared SMILES" "Target ID" "Protein name" "Protein family" "Gene symbol" "Gene ID" Organism Score Rank 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P34913 "Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]" "AB hydrolase superfamily, Epoxide hydrolase family" EPHX2 2053; "Homo sapiens (Human)" 3.18089 1 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 2.93002 2 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 2.52333 3 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P00918 "Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)" "Alpha-carbonic anhydrase family" CA2 760; "Homo sapiens (Human)" 2.51777 4 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 2.48864 5 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 2.48141 6 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 2.2884 7 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P48736 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)" "PI3/PI4-kinase family" PIK3CG 5294; "Homo sapiens (Human)" 2.20496 8 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 2.13655 9 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P0DMS8 "Adenosine receptor A3" "G-protein coupled receptor 1 family" ADORA3 140; "Homo sapiens (Human)" 2.02414 10 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P23141 "Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) (Carboxylesterase 1) (CE-1) (hCE-1) (EC 3.1.1.1) (Cocaine carboxylesterase) (Egasyn) (HMSE) (Methylumbelliferyl-acetate deacetylase 1) (EC 3.1.1.56) (Monocyte/macrophage serine esterase) (Retinyl ester hydrolase) (REH) (Serine esterase 1) (Triacylglycerol hydrolase) (TGH)" "Type-B carboxylesterase/lipase family" CES1 1066; "Homo sapiens (Human)" 1.98622 11 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 Q13547 "Histone deacetylase 1 (HD1) (EC 3.5.1.98)" "Histone deacetylase family, HD type 1 subfamily" HDAC1 3065; "Homo sapiens (Human)" 1.97721 12 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P42345 "Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)" "PI3/PI4-kinase family" MTOR 2475; "Homo sapiens (Human)" 1.9563 13 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P30542 "Adenosine receptor A1" "G-protein coupled receptor 1 family" ADORA1 134; "Homo sapiens (Human)" 1.88996 14 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 Q8NER1 "Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)" "Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamily" TRPV1 7442; "Homo sapiens (Human)" 1.87863 15 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P42336 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)" "PI3/PI4-kinase family" PIK3CA 5290; "Homo sapiens (Human)" 1.87643 16 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 1.86214 17 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.81006 18 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P52732 "Kinesin-like protein KIF11 (Kinesin-like protein 1) (Kinesin-like spindle protein HKSP) (Kinesin-related motor protein Eg5) (Thyroid receptor-interacting protein 5) (TR-interacting protein 5) (TRIP-5)" "TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, BimC subfamily" KIF11 3832; "Homo sapiens (Human)" 1.73596 19 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 1.73221 20 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 1.73138 21 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 Q16790 "Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)" "Alpha-carbonic anhydrase family" CA9 768; "Homo sapiens (Human)" 1.71384 22 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 Q99705 "Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein coupled receptor 24) (MCH-1R) (MCH1R) (MCHR) (SLC-1) (Somatostatin receptor-like protein)" "G-protein coupled receptor 1 family" MCHR1 2847; "Homo sapiens (Human)" 1.69882 23 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 1.69383 24 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P28335 "5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)" "G-protein coupled receptor 1 family" HTR2C 3358; "Homo sapiens (Human)" 1.69293 25 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P11511 "Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase)" "Cytochrome P450 family" CYP19A1 1588; "Homo sapiens (Human)" 1.55891 26 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P00915 "Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase B) (CAB) (Carbonic anhydrase I) (CA-I)" "Alpha-carbonic anhydrase family" CA1 759; "Homo sapiens (Human)" 1.5172 27 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P28221 "5-hydroxytryptamine receptor 1D (5-HT-1D) (5-HT1D) (Serotonin 1D alpha receptor) (5-HT-1D-alpha) (Serotonin receptor 1D)" "G-protein coupled receptor 1 family" HTR1D 3352; "Homo sapiens (Human)" 1.50639 28 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P09874 "Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-)" PARP1 142; "Homo sapiens (Human)" 1.44775 29 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 O43683 "Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)" "Protein kinase superfamily, Ser/Thr protein kinase family, BUB1 subfamily" BUB1 699; "Homo sapiens (Human)" 1.44538 30 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P36897 "TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR1 7046; "Homo sapiens (Human)" 1.43473 31 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.42338 32 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P34972 "Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)" "G-protein coupled receptor 1 family" CNR2 1269; "Homo sapiens (Human)" 1.42056 33 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P25103 "Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1)" "G-protein coupled receptor 1 family" TACR1 6869; "Homo sapiens (Human)" 1.4159 34 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 O43570 "Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)" "Alpha-carbonic anhydrase family" CA12 771; "Homo sapiens (Human)" 1.40995 35 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P15538 "Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase) (EC 1.14.15.4)" "Cytochrome P450 family" CYP11B1 1584; "Homo sapiens (Human)" 1.37488 36 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P29274 "Adenosine receptor A2a" "G-protein coupled receptor 1 family" ADORA2A 135; "Homo sapiens (Human)" 1.37156 37 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 Q02127 "Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase)" "Dihydroorotate dehydrogenase family, Type 2 subfamily" DHODH 1723; "Homo sapiens (Human)" 1.35868 38 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 1.35376 39 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P00742 "Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]" "Peptidase S1 family" F10 2159; "Homo sapiens (Human)" 1.34673 40 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P41597 "C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (Monocyte chemoattractant protein 1 receptor) (MCP-1-R) (CD antigen CD192)" "G-protein coupled receptor 1 family" CCR2 729230; "Homo sapiens (Human)" 1.34442 41 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P00374 "Dihydrofolate reductase (EC 1.5.1.3)" "Dihydrofolate reductase family" DHFR 1719; "Homo sapiens (Human)" 1.34019 42 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 O76074 "cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)" "Cyclic nucleotide phosphodiesterase family" PDE5A 8654; "Homo sapiens (Human)" 1.30262 43 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P28222 "5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (S12) (Serotonin 1D beta receptor) (5-HT-1D-beta) (Serotonin receptor 1B)" "G-protein coupled receptor 1 family" HTR1B 3351; "Homo sapiens (Human)" 1.30018 44 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P29275 "Adenosine receptor A2b" "G-protein coupled receptor 1 family" ADORA2B 136; "Homo sapiens (Human)" 1.29475 45 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P10275 "Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)" "Nuclear hormone receptor family, NR3 subfamily" AR 367; "Homo sapiens (Human)" 1.28823 46 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 1.28001 47 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P32239 "Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R)" "G-protein coupled receptor 1 family" CCKBR 887; "Homo sapiens (Human)" 1.2775 48 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P41595 "5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)" "G-protein coupled receptor 1 family" HTR2B 3357; "Homo sapiens (Human)" 1.23753 49 1 CHEMBL5653589 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12 Cn1nc2c(c1)c(Nc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F)nc(n2)c1cccnc1 P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 1.23574 50 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P34913 "Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]" "AB hydrolase superfamily, Epoxide hydrolase family" EPHX2 2053; "Homo sapiens (Human)" 3.18089 1 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 2.93002 2 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 2.52333 3 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 2.48864 4 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 2.48141 5 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P00918 "Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)" "Alpha-carbonic anhydrase family" CA2 760; "Homo sapiens (Human)" 2.33845 6 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 2.2884 7 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P48736 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)" "PI3/PI4-kinase family" PIK3CG 5294; "Homo sapiens (Human)" 2.25791 8 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P29274 "Adenosine receptor A2a" "G-protein coupled receptor 1 family" ADORA2A 135; "Homo sapiens (Human)" 2.17578 9 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P42345 "Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)" "PI3/PI4-kinase family" MTOR 2475; "Homo sapiens (Human)" 2.15358 10 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 2.13655 11 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F O00329 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)" "PI3/PI4-kinase family" PIK3CD 5293; "Homo sapiens (Human)" 2.09911 12 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P0DMS8 "Adenosine receptor A3" "G-protein coupled receptor 1 family" ADORA3 140; "Homo sapiens (Human)" 2.02414 13 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P30542 "Adenosine receptor A1" "G-protein coupled receptor 1 family" ADORA1 134; "Homo sapiens (Human)" 1.97819 14 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F Q13547 "Histone deacetylase 1 (HD1) (EC 3.5.1.98)" "Histone deacetylase family, HD type 1 subfamily" HDAC1 3065; "Homo sapiens (Human)" 1.97721 15 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F Q8NER1 "Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)" "Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamily" TRPV1 7442; "Homo sapiens (Human)" 1.87863 16 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P42336 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)" "PI3/PI4-kinase family" PIK3CA 5290; "Homo sapiens (Human)" 1.87643 17 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 1.86111 18 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P23141 "Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) (Carboxylesterase 1) (CE-1) (hCE-1) (EC 3.1.1.1) (Cocaine carboxylesterase) (Egasyn) (HMSE) (Methylumbelliferyl-acetate deacetylase 1) (EC 3.1.1.56) (Monocyte/macrophage serine esterase) (Retinyl ester hydrolase) (REH) (Serine esterase 1) (Triacylglycerol hydrolase) (TGH)" "Type-B carboxylesterase/lipase family" CES1 1066; "Homo sapiens (Human)" 1.84476 19 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 1.79025 20 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P52732 "Kinesin-like protein KIF11 (Kinesin-like protein 1) (Kinesin-like spindle protein HKSP) (Kinesin-related motor protein Eg5) (Thyroid receptor-interacting protein 5) (TR-interacting protein 5) (TRIP-5)" "TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, BimC subfamily" KIF11 3832; "Homo sapiens (Human)" 1.73596 21 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 1.68387 22 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 1.6572 23 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.65678 24 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 1.6291 25 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P28335 "5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)" "G-protein coupled receptor 1 family" HTR2C 3358; "Homo sapiens (Human)" 1.60465 26 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F Q16790 "Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)" "Alpha-carbonic anhydrase family" CA9 768; "Homo sapiens (Human)" 1.59178 27 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F Q99705 "Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein coupled receptor 24) (MCH-1R) (MCH1R) (MCHR) (SLC-1) (Somatostatin receptor-like protein)" "G-protein coupled receptor 1 family" MCHR1 2847; "Homo sapiens (Human)" 1.57783 28 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F Q07343 "cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.53) (DPDE4) (PDE32)" "Cyclic nucleotide phosphodiesterase family, PDE4 subfamily" PDE4B 5142; "Homo sapiens (Human)" 1.4838 29 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P78527 "DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)" "PI3/PI4-kinase family" PRKDC 5591; "Homo sapiens (Human)" 1.46367 30 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P11511 "Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase)" "Cytochrome P450 family" CYP19A1 1588; "Homo sapiens (Human)" 1.44789 31 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P00915 "Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase B) (CAB) (Carbonic anhydrase I) (CA-I)" "Alpha-carbonic anhydrase family" CA1 759; "Homo sapiens (Human)" 1.40914 32 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P15538 "Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase) (EC 1.14.15.4)" "Cytochrome P450 family" CYP11B1 1584; "Homo sapiens (Human)" 1.37488 33 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P04150 "Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)" "Nuclear hormone receptor family, NR3 subfamily" NR3C1 2908; "Homo sapiens (Human)" 1.36907 34 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F O43683 "Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)" "Protein kinase superfamily, Ser/Thr protein kinase family, BUB1 subfamily" BUB1 699; "Homo sapiens (Human)" 1.34244 35 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P36897 "TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR1 7046; "Homo sapiens (Human)" 1.3338 36 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F O76074 "cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)" "Cyclic nucleotide phosphodiesterase family" PDE5A 8654; "Homo sapiens (Human)" 1.32562 37 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.32201 38 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P34972 "Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)" "G-protein coupled receptor 1 family" CNR2 1269; "Homo sapiens (Human)" 1.31939 39 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P25103 "Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1)" "G-protein coupled receptor 1 family" TACR1 6869; "Homo sapiens (Human)" 1.31506 40 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F O43570 "Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)" "Alpha-carbonic anhydrase family" CA12 771; "Homo sapiens (Human)" 1.30953 41 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 1.27682 42 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F Q02127 "Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase)" "Dihydroorotate dehydrogenase family, Type 2 subfamily" DHODH 1723; "Homo sapiens (Human)" 1.26191 43 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P00742 "Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]" "Peptidase S1 family" F10 2159; "Homo sapiens (Human)" 1.25082 44 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P41597 "C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (Monocyte chemoattractant protein 1 receptor) (MCP-1-R) (CD antigen CD192)" "G-protein coupled receptor 1 family" CCR2 729230; "Homo sapiens (Human)" 1.24867 45 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P00374 "Dihydrofolate reductase (EC 1.5.1.3)" "Dihydrofolate reductase family" DHFR 1719; "Homo sapiens (Human)" 1.24474 46 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P28222 "5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (S12) (Serotonin 1D beta receptor) (5-HT-1D-beta) (Serotonin receptor 1B)" "G-protein coupled receptor 1 family" HTR1B 3351; "Homo sapiens (Human)" 1.20758 47 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 1.20551 48 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F Q15759 "Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK11 5600; "Homo sapiens (Human)" 1.19875 49 2 CHEMBL3752910 Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C Cc1ccc(cc1Nc1nc(nc2c1cnn2C)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F P10275 "Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)" "Nuclear hormone receptor family, NR3 subfamily" AR 367; "Homo sapiens (Human)" 1.19648 50 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 3.5165 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 3.45142 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 3.43844 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 3.37304 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 3.32 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 3.26216 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q7KZI7 "Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK2 2011; "Homo sapiens (Human)" 3.25782 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 3.18643 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 3.16842 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 3.10935 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 3.08997 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 3.04188 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 2.96332 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 2.94966 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 2.92659 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q16512 "Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN1 5585; "Homo sapiens (Human)" 2.92548 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 2.9234 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 2.91334 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 2.90192 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 2.89594 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UQM7 "Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2A 815; "Homo sapiens (Human)" 2.87371 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 2.85672 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.85146 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13557 "Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2D 817; "Homo sapiens (Human)" 2.85145 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8N5S9 "Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK1 84254; "Homo sapiens (Human)" 2.8083 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P27448 "MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK3 4140; "Homo sapiens (Human)" 2.80263 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 2.79389 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8WTQ7 "Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK7 131890; "Homo sapiens (Human)" 2.75889 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P05771 "Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCB 5579; "Homo sapiens (Human)" 2.7488 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 2.74511 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q16816 "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG1 5260; "Homo sapiens (Human)" 2.74184 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9NWT8 "Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, mitochondrial) (MRP-S38) (Mitochondrial small ribosomal subunit protein mS38)" "Mitochondrion-specific ribosomal protein mS38 family" AURKAIP1 54998; "Homo sapiens (Human)" 2.71701 1 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 2.69143 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 2.68047 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 2.65618 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O94768 "Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17B 9262; "Homo sapiens (Human)" 2.64477 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 2.63679 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P41597 "C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (Monocyte chemoattractant protein 1 receptor) (MCP-1-R) (CD antigen CD192)" "G-protein coupled receptor 1 family" CCR2 729230; "Homo sapiens (Human)" 2.61541 2 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 2.61286 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 2.60884 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15139 "Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD1 5587; "Homo sapiens (Human)" 2.59255 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9P0L2 "Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK1 4139; "Homo sapiens (Human)" 2.57926 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 2.57773 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 2.5735 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 2.571 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 2.55245 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13554 "Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2B 816; "Homo sapiens (Human)" 2.54808 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O00311 "Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamily" CDC7 8317; "Homo sapiens (Human)" 2.52664 3 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13627 "Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1A 1859; "Homo sapiens (Human)" 2.52423 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O96013 "Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK4 10298; "Homo sapiens (Human)" 2.52193 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 2.52098 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9P2K8 "eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK4 440275; "Homo sapiens (Human)" 2.51838 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 2.50386 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 2.48529 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O00141 "Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK1 6446; "Homo sapiens (Human)" 2.47327 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 2.47244 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q99683 "Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K5 4217; "Homo sapiens (Human)" 2.45776 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15835 "Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK1 6011; "Homo sapiens (Human)" 2.45013 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 2.44654 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q00534 "Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK6 1021; "Homo sapiens (Human)" 2.44245 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 2.44181 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 2.42646 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 2.42542 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 2.41244 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15759 "Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK11 5600; "Homo sapiens (Human)" 2.41171 4 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9NRM7 "Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS2 26524; "Homo sapiens (Human)" 2.40524 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q96SB4 "SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK1 6732; "Homo sapiens (Human)" 2.3893 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 2.38662 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9P286 "Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK5 57144; "Homo sapiens (Human)" 2.38262 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 2.37624 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q02156 "Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCE 5581; "Homo sapiens (Human)" 2.36032 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 2.35521 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 2.34579 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q00537 "Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK17 5128; "Homo sapiens (Human)" 2.33596 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 2.33436 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 2.33158 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13546 "Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK1 8737; "Homo sapiens (Human)" 2.33115 5 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 2.32265 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 2.32213 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P42680 "Tyrosine-protein kinase Tec (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TEC 7006; "Homo sapiens (Human)" 2.32209 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 2.3087 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 2.29576 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 2.2817 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q99755 "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)" PIP5K1A 8394; "Homo sapiens (Human)" 2.27782 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P49137 "MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAP-K2) (MAPKAPK-2) (MK-2) (MK2) (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MAPKAPK2 9261; "Homo sapiens (Human)" 2.27644 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 2.27243 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 2.27139 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P51817 "cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) (Protein kinase X-linked) (Serine/threonine-protein kinase PRKX) (EC 2.7.11.1) (Protein kinase PKX1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKX 5613; "Homo sapiens (Human)" 2.27013 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q02779 "Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K10 4294; "Homo sapiens (Human)" 2.26427 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UEE5 "Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17A 9263; "Homo sapiens (Human)" 2.26376 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 2.25314 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 2.25054 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P45985 "Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K4 6416; "Homo sapiens (Human)" 2.24898 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 2.24876 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 2.24733 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 2.24452 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q32MK0 "Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK3 91807; "Homo sapiens (Human)" 2.24029 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P78356 "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta)" PIP4K2B 8396; "Homo sapiens (Human)" 2.23844 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 2.23744 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 2.22869 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 2.2267 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9Y2K2 "Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK3 23387; "Homo sapiens (Human)" 2.22628 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 2.21908 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P04049 "RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" RAF1 5894; "Homo sapiens (Human)" 2.21796 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P43403 "Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" ZAP70 7535; "Homo sapiens (Human)" 2.2156 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8IWQ3 "Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 2) (BR serine/threonine-protein kinase 2) (Serine/threonine-protein kinase 29) (Serine/threonine-protein kinase SAD-A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK2 9024; "Homo sapiens (Human)" 2.21493 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 2.21422 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 2.20408 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q6ZN16 "Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K15 389840; "Homo sapiens (Human)" 2.20263 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q96L34 "MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK4 57787; "Homo sapiens (Human)" 2.1995 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 2.18629 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13490 "Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2)" "IAP family" BIRC2 329; "Homo sapiens (Human)" 2.18472 6 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q07002 "Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK18 5129; "Homo sapiens (Human)" 2.18442 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P24723 "Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCH 5583; "Homo sapiens (Human)" 2.18328 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P53355 "Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK1 1612; "Homo sapiens (Human)" 2.18059 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 2.17936 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q04759 "Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCQ 5588; "Homo sapiens (Human)" 2.17721 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 2.17639 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q05655 "Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCD 5580; "Homo sapiens (Human)" 2.16692 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P11309 "Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM1 5292; "Homo sapiens (Human)" 2.16639 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 2.1607 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 2.15883 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 2.15852 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 2.14792 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 2.14374 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 2.13941 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 2.13659 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 2.1351 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 2.13077 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 2.12559 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13555 "Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2G 818; "Homo sapiens (Human)" 2.11357 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O15111 "Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" CHUK 1147; "Homo sapiens (Human)" 2.11182 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O76039 "Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL5 6792; "Homo sapiens (Human)" 2.11019 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8TD08 "Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK15 225689; "Homo sapiens (Human)" 2.11011 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q96BR1 "Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK3 100533105;23678; "Homo sapiens (Human)" 2.10321 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 2.10221 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 2.10174 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 2.09661 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9NQU5 "Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) (PAK-6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK6 106821730;56924; "Homo sapiens (Human)" 2.09315 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O15264 "Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK13 5603; "Homo sapiens (Human)" 2.09239 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 2.09112 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 2.0902 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P05129 "Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCG 5582; "Homo sapiens (Human)" 2.08907 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13153 "Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK1 5058; "Homo sapiens (Human)" 2.08648 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O14730 "Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK3 8780; "Homo sapiens (Human)" 2.07414 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 2.07413 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 2.07039 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 2.06891 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9BRS2 "Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK1 83732; "Homo sapiens (Human)" 2.06836 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 2.0617 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O14936 "Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; MAGUK family" CASK 8573; "Homo sapiens (Human)" 2.05512 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 2.05366 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 2.05231 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O75914 "Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK3 5063; "Homo sapiens (Human)" 2.05108 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P34972 "Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)" "G-protein coupled receptor 1 family" CNR2 1269; "Homo sapiens (Human)" 2.04673 7 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 2.02351 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9Y463 "Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1B 9149; "Homo sapiens (Human)" 2.01798 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13237 "cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG2 5593; "Homo sapiens (Human)" 2.00934 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9NYY3 "Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) (Serine/threonine-protein kinase SNK) (hSNK) (Serum-inducible kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK2 10769; "Homo sapiens (Human)" 2.00417 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UIK4 "Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK2 23604; "Homo sapiens (Human)" 1.99892 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P09874 "Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-)" PARP1 142; "Homo sapiens (Human)" 1.99866 8 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 1.9923 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 1.98348 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 1.97888 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q00532 "Cyclin-dependent kinase-like 1 (EC 2.7.11.22) (Protein kinase p42 KKIALRE) (Serine/threonine-protein kinase KKIALRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL1 8814; "Homo sapiens (Human)" 1.9748 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q99558 "Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K14 9020; "Homo sapiens (Human)" 1.96108 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 1.96068 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 1.95597 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 1.95538 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 1.95313 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.9481 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 1.94284 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q6XUX3 "Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)" "Protein kinase superfamily, Ser/Thr protein kinase family" DSTYK 25778; "Homo sapiens (Human)" 1.93567 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 1.93558 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 1.93028 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 1.92775 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.92743 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8TDC3 "Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK1 84446; "Homo sapiens (Human)" 1.92698 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.92658 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q86YV6 "Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK4 340156; "Homo sapiens (Human)" 1.9244 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P22694 "cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACB 5567; "Homo sapiens (Human)" 1.92061 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 1.91523 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13177 "Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK2 5062; "Homo sapiens (Human)" 1.91435 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15046 "Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)" "Class-II aminoacyl-tRNA synthetase family" KARS 3735; "Homo sapiens (Human)" 1.91308 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 1.91024 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P17252 "Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCA 5578; "Homo sapiens (Human)" 1.90972 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q5VT25 "Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPA 8476; "Homo sapiens (Human)" 1.90562 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P57078 "Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK4 "Homo sapiens (Human)" 1.89615 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q02763 "Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TEK 7010; "Homo sapiens (Human)" 1.88641 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9H1R3 "Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK2 85366; "Homo sapiens (Human)" 1.87713 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.87236 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q14012 "Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1 8536; "Homo sapiens (Human)" 1.87117 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q00526 "Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK3 1018; "Homo sapiens (Human)" 1.86379 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 1.85694 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 1.85607 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P78362 "SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK2 6733; "Homo sapiens (Human)" 1.85161 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q09013 "Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) (DMPK) (Myotonic dystrophy protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" DMPK 1760; "Homo sapiens (Human)" 1.84553 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P36897 "TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR1 7046; "Homo sapiens (Human)" 1.84443 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.84279 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9BX84 "Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6)" "Protein kinase superfamily, Alpha-type protein kinase family, ALPK subfamily; Transient receptor (TC 1.A.4) family, LTrpC subfamily, TRPM6 sub-subfamily" TRPM6 140803; "Homo sapiens (Human)" 1.84011 9 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q52WX2 "Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" SBK1 388228; "Homo sapiens (Human)" 1.8378 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 1.83039 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 1.83039 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P54646 "5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA2 5563; "Homo sapiens (Human)" 1.82772 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P14616 "Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSRR 3645; "Homo sapiens (Human)" 1.81962 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 1.80551 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.80542 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 1.79887 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 1.7973 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P80370 "Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen 1 (FA1)]" DLK1 8788; "Homo sapiens (Human)" 1.79343 10 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 1.7913 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 1.79112 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O95835 "Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS1 9113; "Homo sapiens (Human)" 1.78982 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9BWU1 "Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK19 23097; "Homo sapiens (Human)" 1.7743 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 1.77375 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8NFD2 "Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" ANKK1 255239; "Homo sapiens (Human)" 1.77334 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 1.76623 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O94921 "Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK14 5218; "Homo sapiens (Human)" 1.76458 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 1.76344 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 1.75885 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O75460 "Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]" "Protein kinase superfamily, Ser/Thr protein kinase family" ERN1 2081; "Homo sapiens (Human)" 1.75403 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 1.75366 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13976 "cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG1 5592; "Homo sapiens (Human)" 1.74683 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 1.73309 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 1.73295 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 1.72343 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.72288 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 1.7176 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 1.70823 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 1.69854 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9C098 "Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK3 85443; "Homo sapiens (Human)" 1.68807 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P78527 "DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)" "PI3/PI4-kinase family" PRKDC 5591; "Homo sapiens (Human)" 1.67977 11 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.67668 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P0C264 "Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family member 3) (Sugen kinase 110)" "Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamily" SBK3 100130827; "Homo sapiens (Human)" 1.67469 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 1.66796 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15910 "Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.43) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)" "Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, EZ subfamily" EZH2 2146; "Homo sapiens (Human)" 1.66634 12 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q96D53 "Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase 4) (Coenzyme Q protein 8B)" "Protein kinase superfamily, ADCK protein kinase family" COQ8B 79934; "Homo sapiens (Human)" 1.66633 13 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15750 "TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 1) (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1)" TAB1 10454; "Homo sapiens (Human)" 1.66559 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15831 "Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamily" STK11 6794; "Homo sapiens (Human)" 1.66097 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 1.65622 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13489 "Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)" "IAP family" BIRC3 330; "Homo sapiens (Human)" 1.65176 14 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.64735 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q86UE8 "Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family" TLK2 11011; "Homo sapiens (Human)" 1.64707 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9BXA7 "Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK1B 83942; "Homo sapiens (Human)" 1.6464 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O00506 "Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK25 10494; "Homo sapiens (Human)" 1.64578 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 1.63725 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q92630 "Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK2 8445; "Homo sapiens (Human)" 1.63181 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 1.62682 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UKI8 "Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" TLK1 9874; "Homo sapiens (Human)" 1.62437 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 1.6197 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9Y2H9 "Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" MAST1 22983; "Homo sapiens (Human)" 1.6185 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 1.61803 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9Y6E0 "Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK24 8428; "Homo sapiens (Human)" 1.61431 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P53778 "Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK12 6300; "Homo sapiens (Human)" 1.60958 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9NY57 "Serine/threonine-protein kinase 32B (EC 2.7.11.1) (Yet another novel kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32B 55351; "Homo sapiens (Human)" 1.60659 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P52564 "Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6) (Stress-activated protein kinase kinase 3) (SAPK kinase 3) (SAPKK-3) (SAPKK3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K6 5608; "Homo sapiens (Human)" 1.60527 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q00535 "Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK5 1020; "Homo sapiens (Human)" 1.60446 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 1.60261 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 1.59113 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9NRH2 "SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" SNRK 54861; "Homo sapiens (Human)" 1.59047 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.57742 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.57512 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P42336 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)" "PI3/PI4-kinase family" PIK3CA 5290; "Homo sapiens (Human)" 1.5692 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 1.56482 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q96NX5 "Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I gamma) (CaM kinase IG) (CaM-KI gamma) (CaMKI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1G 57172; "Homo sapiens (Human)" 1.55185 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P0DMS8 "Adenosine receptor A3" "G-protein coupled receptor 1 family" ADORA3 140; "Homo sapiens (Human)" 1.54668 15 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 1.54544 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O14733 "Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (Stress-activated protein kinase kinase 4) (SAPK kinase 4) (SAPKK-4) (SAPKK4) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K7 5609; "Homo sapiens (Human)" 1.5452 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P00734 "Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain]" "Peptidase S1 family" F2 2147; "Homo sapiens (Human)" 1.53021 16 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P98170 "E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP-like protein) (ILP) (hILP) (Inhibitor of apoptosis protein 3) (IAP-3) (hIAP-3) (hIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP)" "IAP family" XIAP 331; "Homo sapiens (Human)" 1.52662 17 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P42345 "Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)" "PI3/PI4-kinase family" MTOR 2475; "Homo sapiens (Human)" 1.51681 18 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.51643 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 1.50458 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P15538 "Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase) (EC 1.14.15.4)" "Cytochrome P450 family" CYP11B1 1584; "Homo sapiens (Human)" 1.50375 19 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 1.50172 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 1.49569 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13523 "Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" PRPF4B 8899; "Homo sapiens (Human)" 1.49318 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 1.48499 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 1.48033 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P06400 "Retinoblastoma-associated protein (p105-Rb) (pRb) (Rb) (pp110)" "Retinoblastoma protein (RB) family" RB1 5925; "Homo sapiens (Human)" 1.47877 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 1.47695 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P50406 "5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)" "G-protein coupled receptor 1 family" HTR6 3362; "Homo sapiens (Human)" 1.47283 20 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O43172 "U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4)" PRPF4 9128; "Homo sapiens (Human)" 1.46114 21 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P48729 "Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1 1452; "Homo sapiens (Human)" 1.45337 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 1.453 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P36896 "Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1B 91; "Homo sapiens (Human)" 1.45286 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P22612 "cAMP-dependent protein kinase catalytic subunit gamma (PKA C-gamma) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACG 5568; "Homo sapiens (Human)" 1.45283 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q00536 "Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK16 5127; "Homo sapiens (Human)" 1.44906 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.44692 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 1.44046 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8NEV4 "Myosin-IIIa (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3A 53904; "Homo sapiens (Human)" 1.43452 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P48736 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)" "PI3/PI4-kinase family" PIK3CG 5294; "Homo sapiens (Human)" 1.43229 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O43781 "Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1) (Regulatory erythroid kinase) (REDK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK3 8444; "Homo sapiens (Human)" 1.425 22 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9H4B4 "Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3) (Proliferation-related kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK3 1263; "Homo sapiens (Human)" 1.41426 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O14920 "Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKB 3551; "Homo sapiens (Human)" 1.41196 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 1.40972 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UBE8 "Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" NLK 51701; "Homo sapiens (Human)" 1.39746 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P31749 "RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT1 207; "Homo sapiens (Human)" 1.39445 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P30291 "Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE1 7465; "Homo sapiens (Human)" 1.39385 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8IW41 "MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAP-K5) (MAPKAPK-5) (MK-5) (MK5) (EC 2.7.11.1) (p38-regulated/activated protein kinase) (PRAK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MAPKAPK5 8550; "Homo sapiens (Human)" 1.39242 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15208 "Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" STK38 11329; "Homo sapiens (Human)" 1.38873 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9BQI3 "Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled repressor) (HCR) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Hemin-sensitive initiation factor 2-alpha kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK1 27102; "Homo sapiens (Human)" 1.3796 23 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 1.37889 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O14578 "Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" CIT 11113; "Homo sapiens (Human)" 1.37755 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q96PF2 "Testis-specific serine/threonine-protein kinase 2 (TSK-2) (TSK2) (TSSK-2) (Testis-specific kinase 2) (EC 2.7.11.1) (DiGeorge syndrome protein G) (DGS-G) (Serine/threonine-protein kinase 22B)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK2 23617; "Homo sapiens (Human)" 1.37418 24 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P27986 "Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)" "PI3K p85 subunit family" PIK3R1 5295; "Homo sapiens (Human)" 1.36567 25 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q01538 "Myelin transcription factor 1 (MyT1) (Myelin transcription factor I) (MyTI) (PLPB1) (Proteolipid protein-binding protein)" "MYT1 family" MYT1 4661; "Homo sapiens (Human)" 1.35572 26 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 1.34856 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 1.34833 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O95382 "Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K6 9064; "Homo sapiens (Human)" 1.34793 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13164 "Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK7 5598; "Homo sapiens (Human)" 1.34576 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P49674 "Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1E 102800317;1454; "Homo sapiens (Human)" 1.34442 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P41240 "Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" CSK 1445; "Homo sapiens (Human)" 1.34432 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9Y2H1 "Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" STK38L 23012; "Homo sapiens (Human)" 1.34046 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P22455 "Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR4 2264; "Homo sapiens (Human)" 1.31252 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O15146 "Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)" "Protein kinase superfamily, Tyr protein kinase family" MUSK 4593; "Homo sapiens (Human)" 1.31215 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P19525 "Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK2 5610; "Homo sapiens (Human)" 1.31188 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 1.30939 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q86UX6 "Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (Yet another novel kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32C 282974; "Homo sapiens (Human)" 1.30754 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 1.29953 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.29399 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9HC98 "Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6) (Protein kinase SID6-1512)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK6 10783; "Homo sapiens (Human)" 1.29271 27 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q92772 "Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL2 8999; "Homo sapiens (Human)" 1.28187 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9P289 "Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK26 51765; "Homo sapiens (Human)" 1.27797 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 1.27761 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P28482 "Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK1 5594; "Homo sapiens (Human)" 1.27647 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UQ88 "Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 2) (Cell division protein kinase 11A) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK11A 728642; "Homo sapiens (Human)" 1.27474 28 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P41143 "Delta-type opioid receptor (D-OR-1) (DOR-1)" "G-protein coupled receptor 1 family" OPRD1 4985; "Homo sapiens (Human)" 1.27033 29 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.25004 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q96Q40 "Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK15 65061; "Homo sapiens (Human)" 1.24713 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P49116 "Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TAK1) (Orphan nuclear receptor TR4) (Testicular receptor 4)" "Nuclear hormone receptor family, NR2 subfamily" NR2C2 7182; "Homo sapiens (Human)" 1.24638 30 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.24601 31 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 1.22966 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9BUB5 "MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK1 8569; "Homo sapiens (Human)" 1.22856 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8TBX8 "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma)" PIP4K2C 79837; "Homo sapiens (Human)" 1.22467 32 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P57058 "Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase MAK-V)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" HUNK 30811; "Homo sapiens (Human)" 1.22386 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P21860 "Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB3 2065; "Homo sapiens (Human)" 1.21896 33 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15375 "Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA7 2045; "Homo sapiens (Human)" 1.21317 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9NR20 "Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK4 8798; "Homo sapiens (Human)" 1.20856 34 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P34947 "G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK5 2869; "Homo sapiens (Human)" 1.20854 35 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9Y5Y9 "Sodium channel protein type 10 subunit alpha (Peripheral nerve sodium channel 3) (PN3) (hPN3) (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8)" "Sodium channel (TC 1.A.1.10) family, Nav1.8/SCN10A subfamily" SCN10A 6336; "Homo sapiens (Human)" 1.19737 36 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 1.19494 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 1.194 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O00750 "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta)" "PI3/PI4-kinase family" PIK3C2B 5287; "Homo sapiens (Human)" 1.18871 37 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 1.18205 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P28335 "5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)" "G-protein coupled receptor 1 family" HTR2C 3358; "Homo sapiens (Human)" 1.18065 38 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P31751 "RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC-PK-beta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT2 208; "Homo sapiens (Human)" 1.17568 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 1.1734 39 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q99640 "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" PKMYT1 9088; "Homo sapiens (Human)" 1.17335 40 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P10398 "Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" ARAF 369; "Homo sapiens (Human)" 1.17292 41 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UEW8 "STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK39 27347; "Homo sapiens (Human)" 1.17279 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P37023 "Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVRL1 94; "Homo sapiens (Human)" 1.1713 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8IY84 "Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" NIM1K 167359; "Homo sapiens (Human)" 1.16768 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q16566 "Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK4 814; "Homo sapiens (Human)" 1.16745 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O00329 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)" "PI3/PI4-kinase family" PIK3CD 5293; "Homo sapiens (Human)" 1.16724 42 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P49286 "Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)" "G-protein coupled receptor 1 family" MTNR1B 4544; "Homo sapiens (Human)" 1.16203 43 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P41743 "Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (PRKC-lambda/iota) (aPKC-lambda/iota) (nPKC-iota)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCI 5584; "Homo sapiens (Human)" 1.16104 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P29371 "Neuromedin-K receptor (NKR) (NK-3 receptor) (NK-3R) (Neurokinin B receptor) (Tachykinin receptor 3)" "G-protein coupled receptor 1 family" TACR3 6870; "Homo sapiens (Human)" 1.15584 44 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P53350 "Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK1 5347; "Homo sapiens (Human)" 1.14228 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P21127 "Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK11B 984; "Homo sapiens (Human)" 1.13667 45 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8WU08 "Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32A 202374; "Homo sapiens (Human)" 1.13504 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8NER1 "Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)" "Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamily" TRPV1 7442; "Homo sapiens (Human)" 1.12643 46 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 1.11731 47 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8TD19 "Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK9 91754; "Homo sapiens (Human)" 1.10981 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 1.10901 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P37173 "TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR2 7048; "Homo sapiens (Human)" 1.10776 48 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P49761 "Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK3 1198; "Homo sapiens (Human)" 1.10183 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9NYL2 "Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K20 51776; "Homo sapiens (Human)" 1.10112 49 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15569 "Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" TESK1 7016; "Homo sapiens (Human)" 1.09846 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P11229 "Muscarinic acetylcholine receptor M1" "G-protein coupled receptor 1 family, Muscarinic acetylcholine receptor subfamily, CHRM1 sub-subfamily" CHRM1 1128; "Homo sapiens (Human)" 1.09802 50 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 1.0964 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O75747 "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma (PI3K-C2-gamma) (PtdIns-3-kinase C2 subunit gamma) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-gamma)" "PI3/PI4-kinase family" PIK3C2G 5288; "Homo sapiens (Human)" 1.09347 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13233 "Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K1 4214; "Homo sapiens (Human)" 1.08971 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q59H18 "Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" TNNI3K 100526835;51086; "Homo sapiens (Human)" 1.08568 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P78368 "Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G2 1455; "Homo sapiens (Human)" 1.08431 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P42679 "Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" MATK 4145; "Homo sapiens (Human)" 1.08028 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8WXR4 "Myosin-IIIb (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3B 140469; "Homo sapiens (Human)" 1.07854 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P36894 "Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1A 657; "Homo sapiens (Human)" 1.04383 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 1.03951 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8N568 "Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin domain-containing protein 3B) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK2 166614; "Homo sapiens (Human)" 1.03224 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8NG66 "Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK11 79858; "Homo sapiens (Human)" 1.02733 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9Y5S2 "Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (CDC42BP-beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPB 9578; "Homo sapiens (Human)" 1.00357 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P20794 "Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" MAK 4117; "Homo sapiens (Human)" 1.00152 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P54756 "Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA5 2044; "Homo sapiens (Human)" 0.980192 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9BVS4 "Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK2 55781; "Homo sapiens (Human)" 0.974281 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P53671 "LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK2 3985; "Homo sapiens (Human)" 0.962138 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9Y243 "RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT3 10000; "Homo sapiens (Human)" 0.958426 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q6DT37 "Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (MRCKG) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPG 55561; "Homo sapiens (Human)" 0.948141 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P51955 "Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK2 4751; "Homo sapiens (Human)" 0.936435 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 0.918909 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 0.916893 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9UBF8 "Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) (NPIK) (PI4K92)" "PI3/PI4-kinase family, Type III PI4K subfamily" PI4KB 5298; "Homo sapiens (Human)" 0.913031 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8TDX7 "Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK7 140609; "Homo sapiens (Human)" 0.909295 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O15075 "Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK1 9201; "Homo sapiens (Human)" 0.896682 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P54764 "Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA4 2043; "Homo sapiens (Human)" 0.869362 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13705 "Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2B 93; "Homo sapiens (Human)" 0.868313 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q16659 "Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK6 5597; "Homo sapiens (Human)" 0.864661 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13873 "Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR2 659; "Homo sapiens (Human)" 0.857896 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 0.839082 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9HCP0 "Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G1 53944; "Homo sapiens (Human)" 0.830885 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 0.798916 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q96PY6 "Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK1 4750; "Homo sapiens (Human)" 0.78618 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9Y6R4 "Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K4 4216; "Homo sapiens (Human)" 0.783115 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8N752 "Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1L 122011; "Homo sapiens (Human)" 0.779957 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8IVW4 "Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine-protein kinase NKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL3 51265; "Homo sapiens (Human)" 0.717345 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O43353 "Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK2 8767; "Homo sapiens (Human)" 0.709342 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P27037 "Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2A 92; "Homo sapiens (Human)" 0.701274 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O60331 "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma)" PIP5K1C 23396; "Homo sapiens (Human)" 0.690692 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P29323 "Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB2 2048; "Homo sapiens (Human)" 0.66702 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P27361 "Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK3 5595; "Homo sapiens (Human)" 0.665679 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q6P3R8 "Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase 5) (NimA-related protein kinase 5)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK5 341676; "Homo sapiens (Human)" 0.654568 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O95747 "Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" OXSR1 9943; "Homo sapiens (Human)" 0.64994 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q05513 "Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCZ 5590; "Homo sapiens (Human)" 0.479458 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O14746 "Telomerase reverse transcriptase (EC 2.7.7.49) (HEST2) (Telomerase catalytic subunit) (Telomerase-associated protein 2) (TP2)" "Reverse transcriptase family, Telomerase subfamily" TERT 7015; "Homo sapiens (Human)" 0.473849 Known 3 CHEMBL388978 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9NRP7 "Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK36 27148; "Homo sapiens (Human)" 0.455902 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 3.58997 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 3.5165 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 3.43844 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 3.37304 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 3.32 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 3.26216 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q7KZI7 "Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK2 2011; "Homo sapiens (Human)" 3.25782 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 3.19209 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 3.18643 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 3.16842 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 3.11695 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 2.96332 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 2.92658 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 2.92339 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 2.91334 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UQM7 "Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2A 815; "Homo sapiens (Human)" 2.89923 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 2.89594 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 2.87559 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 2.85672 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.85145 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13557 "Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2D 817; "Homo sapiens (Human)" 2.85145 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 2.84268 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8N5S9 "Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK1 84254; "Homo sapiens (Human)" 2.8083 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P27448 "MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK3 4140; "Homo sapiens (Human)" 2.80263 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 2.79897 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q15759 "Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK11 5600; "Homo sapiens (Human)" 2.78877 1 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 2.78673 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8WTQ7 "Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK7 131890; "Homo sapiens (Human)" 2.75889 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 2.7559 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 2.75249 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P05771 "Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCB 5579; "Homo sapiens (Human)" 2.7488 2 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 2.74511 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q16816 "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG1 5260; "Homo sapiens (Human)" 2.74184 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 2.68047 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 2.67466 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 2.65618 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 2.64823 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O94768 "Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17B 9262; "Homo sapiens (Human)" 2.64477 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 2.63679 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q16512 "Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN1 5585; "Homo sapiens (Human)" 2.62143 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 2.61286 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q02779 "Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K10 4294; "Homo sapiens (Human)" 2.6126 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 2.60884 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q15139 "Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD1 5587; "Homo sapiens (Human)" 2.59255 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9P0L2 "Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK1 4139; "Homo sapiens (Human)" 2.57926 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 2.5735 3 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 2.57238 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 2.55245 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9P286 "Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK5 57144; "Homo sapiens (Human)" 2.54857 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 2.54005 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9NQU5 "Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) (PAK-6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK6 106821730;56924; "Homo sapiens (Human)" 2.52777 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13627 "Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1A 1859; "Homo sapiens (Human)" 2.52423 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 2.52098 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9P2K8 "eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK4 440275; "Homo sapiens (Human)" 2.51838 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 2.48529 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13546 "Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK1 8737; "Homo sapiens (Human)" 2.48248 4 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 2.47518 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 2.47244 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 2.46864 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q15835 "Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK1 6011; "Homo sapiens (Human)" 2.45013 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 2.44181 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 2.43358 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 2.42646 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 2.42542 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 2.42481 5 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9NRM7 "Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS2 26524; "Homo sapiens (Human)" 2.40524 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q96SB4 "SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK1 6732; "Homo sapiens (Human)" 2.3893 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 2.36691 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q02156 "Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCE 5581; "Homo sapiens (Human)" 2.36032 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 2.35522 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 2.34579 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q00537 "Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK17 5128; "Homo sapiens (Human)" 2.33596 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 2.33436 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 2.33158 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 2.32265 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P42680 "Tyrosine-protein kinase Tec (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TEC 7006; "Homo sapiens (Human)" 2.32209 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 2.3087 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 2.29576 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9Y463 "Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1B 9149; "Homo sapiens (Human)" 2.2831 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 2.28033 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q99755 "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)" PIP5K1A 8394; "Homo sapiens (Human)" 2.27783 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P49137 "MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAP-K2) (MAPKAPK-2) (MK-2) (MK2) (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MAPKAPK2 9261; "Homo sapiens (Human)" 2.27645 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q99683 "Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K5 4217; "Homo sapiens (Human)" 2.27435 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 2.27243 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 2.27139 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UEE5 "Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17A 9263; "Homo sapiens (Human)" 2.26376 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 2.25314 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 2.25054 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P45985 "Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K4 6416; "Homo sapiens (Human)" 2.24898 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 2.24733 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 2.24452 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9NWT8 "Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, mitochondrial) (MRP-S38) (Mitochondrial small ribosomal subunit protein mS38)" "Mitochondrion-specific ribosomal protein mS38 family" AURKAIP1 54998; "Homo sapiens (Human)" 2.24202 6 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P78356 "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta)" PIP4K2B 8396; "Homo sapiens (Human)" 2.23844 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 2.23744 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 2.2347 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 2.22869 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 2.2267 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9Y2K2 "Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK3 23387; "Homo sapiens (Human)" 2.22628 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 2.21908 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8IWQ3 "Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 2) (BR serine/threonine-protein kinase 2) (Serine/threonine-protein kinase 29) (Serine/threonine-protein kinase SAD-A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK2 9024; "Homo sapiens (Human)" 2.21493 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 2.21422 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 2.21176 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8TD08 "Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK15 225689; "Homo sapiens (Human)" 2.20402 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q6ZN16 "Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K15 389840; "Homo sapiens (Human)" 2.20263 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P31749 "RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT1 207; "Homo sapiens (Human)" 2.18584 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P24723 "Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCH 5583; "Homo sapiens (Human)" 2.18328 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 2.18323 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P53355 "Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK1 1612; "Homo sapiens (Human)" 2.18059 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 2.17936 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q04759 "Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCQ 5588; "Homo sapiens (Human)" 2.17721 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9NYY3 "Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) (Serine/threonine-protein kinase SNK) (hSNK) (Serum-inducible kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK2 10769; "Homo sapiens (Human)" 2.17448 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q05655 "Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCD 5580; "Homo sapiens (Human)" 2.16692 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P11309 "Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM1 5292; "Homo sapiens (Human)" 2.16639 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 2.15883 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 2.15852 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 2.15146 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 2.14791 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 2.14374 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 2.13941 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 2.13659 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 2.1351 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 2.13148 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 2.13077 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q96L34 "MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK4 57787; "Homo sapiens (Human)" 2.13006 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 2.12041 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 2.11372 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13555 "Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2G 818; "Homo sapiens (Human)" 2.11357 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O15111 "Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" CHUK 1147; "Homo sapiens (Human)" 2.11182 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q00536 "Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK16 5127; "Homo sapiens (Human)" 2.11034 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O76039 "Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL5 6792; "Homo sapiens (Human)" 2.11019 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 2.10539 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q96BR1 "Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK3 100533105;23678; "Homo sapiens (Human)" 2.10321 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 2.10221 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 2.10174 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 2.09661 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O15264 "Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK13 5603; "Homo sapiens (Human)" 2.09239 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 2.09112 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 2.08944 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P43403 "Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" ZAP70 7535; "Homo sapiens (Human)" 2.08931 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P05129 "Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCG 5582; "Homo sapiens (Human)" 2.08907 7 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O96013 "Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK4 10298; "Homo sapiens (Human)" 2.07883 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13554 "Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2B 816; "Homo sapiens (Human)" 2.07785 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P36897 "TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR1 7046; "Homo sapiens (Human)" 2.07655 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O14730 "Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK3 8780; "Homo sapiens (Human)" 2.07414 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 2.07413 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 2.07039 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9BRS2 "Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK1 83732; "Homo sapiens (Human)" 2.06836 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 2.05366 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 2.05231 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O75914 "Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK3 5063; "Homo sapiens (Human)" 2.05108 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13153 "Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK1 5058; "Homo sapiens (Human)" 2.03808 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13177 "Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK2 5062; "Homo sapiens (Human)" 2.0255 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 2.02351 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13237 "cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG2 5593; "Homo sapiens (Human)" 2.00934 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 2.00726 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 2.00195 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UIK4 "Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK2 23604; "Homo sapiens (Human)" 1.99892 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P51817 "cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) (Protein kinase X-linked) (Serine/threonine-protein kinase PRKX) (EC 2.7.11.1) (Protein kinase PKX1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKX 5613; "Homo sapiens (Human)" 1.99514 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 1.9923 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9Y2H9 "Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" MAST1 22983; "Homo sapiens (Human)" 1.99135 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 1.98348 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 1.97888 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q00532 "Cyclin-dependent kinase-like 1 (EC 2.7.11.22) (Protein kinase p42 KKIALRE) (Serine/threonine-protein kinase KKIALRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL1 8814; "Homo sapiens (Human)" 1.9748 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 1.97381 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 1.96218 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 1.96068 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 1.95597 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 1.95537 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 1.95313 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P34972 "Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)" "G-protein coupled receptor 1 family" CNR2 1269; "Homo sapiens (Human)" 1.95028 8 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 1.94651 9 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 1.94284 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 1.93558 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 1.93028 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.92987 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 1.92775 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.92744 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8TDC3 "Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK1 84446; "Homo sapiens (Human)" 1.92698 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.92658 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q86YV6 "Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK4 340156; "Homo sapiens (Human)" 1.9244 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P22694 "cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACB 5567; "Homo sapiens (Human)" 1.92061 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 1.91523 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P53671 "LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK2 3985; "Homo sapiens (Human)" 1.91364 10 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P17252 "Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCA 5578; "Homo sapiens (Human)" 1.90972 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q14012 "Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1 8536; "Homo sapiens (Human)" 1.9077 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P57078 "Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK4 "Homo sapiens (Human)" 1.89615 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 1.89492 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 1.89101 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q02763 "Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TEK 7010; "Homo sapiens (Human)" 1.88641 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 1.88298 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9H1R3 "Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK2 85366; "Homo sapiens (Human)" 1.87713 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q00526 "Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK3 1018; "Homo sapiens (Human)" 1.86379 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 1.85607 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P78362 "SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK2 6733; "Homo sapiens (Human)" 1.85161 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q09013 "Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) (DMPK) (Myotonic dystrophy protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" DMPK 1760; "Homo sapiens (Human)" 1.84553 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O14936 "Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; MAGUK family" CASK 8573; "Homo sapiens (Human)" 1.84384 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.84279 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q52WX2 "Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" SBK1 388228; "Homo sapiens (Human)" 1.8378 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q07002 "Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK18 5129; "Homo sapiens (Human)" 1.83493 11 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P54646 "5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA2 5563; "Homo sapiens (Human)" 1.82772 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.81129 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 1.80551 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.80542 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 1.7973 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O14578 "Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" CIT 11113; "Homo sapiens (Human)" 1.7962 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O00311 "Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamily" CDC7 8317; "Homo sapiens (Human)" 1.7938 12 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P80370 "Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen 1 (FA1)]" DLK1 8788; "Homo sapiens (Human)" 1.79343 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O95835 "Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS1 9113; "Homo sapiens (Human)" 1.78982 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P36896 "Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1B 91; "Homo sapiens (Human)" 1.78108 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 1.77838 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 1.77375 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8NFD2 "Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" ANKK1 255239; "Homo sapiens (Human)" 1.77334 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 1.7725 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q6XUX3 "Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)" "Protein kinase superfamily, Ser/Thr protein kinase family" DSTYK 25778; "Homo sapiens (Human)" 1.77128 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 1.76623 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O94921 "Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK14 5218; "Homo sapiens (Human)" 1.76458 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 1.76344 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O75460 "Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]" "Protein kinase superfamily, Ser/Thr protein kinase family" ERN1 2081; "Homo sapiens (Human)" 1.75403 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 1.75366 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13976 "cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG1 5592; "Homo sapiens (Human)" 1.74683 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 1.73295 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q59H18 "Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" TNNI3K 100526835;51086; "Homo sapiens (Human)" 1.72401 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 1.72343 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.72288 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 1.7176 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 1.7165 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9BWU1 "Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK19 23097; "Homo sapiens (Human)" 1.71135 13 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q15375 "Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA7 2045; "Homo sapiens (Human)" 1.70512 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 1.69854 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P11229 "Muscarinic acetylcholine receptor M1" "G-protein coupled receptor 1 family, Muscarinic acetylcholine receptor subfamily, CHRM1 sub-subfamily" CHRM1 1128; "Homo sapiens (Human)" 1.69354 14 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9C098 "Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK3 85443; "Homo sapiens (Human)" 1.68807 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9BXA7 "Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK1B 83942; "Homo sapiens (Human)" 1.68683 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P0C264 "Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family member 3) (Sugen kinase 110)" "Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamily" SBK3 100130827; "Homo sapiens (Human)" 1.67469 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 1.66796 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q15831 "Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamily" STK11 6794; "Homo sapiens (Human)" 1.66097 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O75747 "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma (PI3K-C2-gamma) (PtdIns-3-kinase C2 subunit gamma) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-gamma)" "PI3/PI4-kinase family" PIK3C2G 5288; "Homo sapiens (Human)" 1.65904 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 1.65622 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.64735 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q86UE8 "Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family" TLK2 11011; "Homo sapiens (Human)" 1.64707 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O00506 "Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK25 10494; "Homo sapiens (Human)" 1.64578 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P78527 "DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)" "PI3/PI4-kinase family" PRKDC 5591; "Homo sapiens (Human)" 1.63947 15 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 1.63725 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q92630 "Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK2 8445; "Homo sapiens (Human)" 1.63181 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 1.62653 16 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UKI8 "Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" TLK1 9874; "Homo sapiens (Human)" 1.62437 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.62284 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 1.6197 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 1.60976 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P21860 "Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB3 2065; "Homo sapiens (Human)" 1.60963 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P53778 "Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK12 6300; "Homo sapiens (Human)" 1.60958 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P52564 "Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6) (Stress-activated protein kinase kinase 3) (SAPK kinase 3) (SAPKK-3) (SAPKK3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K6 5608; "Homo sapiens (Human)" 1.60527 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q00535 "Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK5 1020; "Homo sapiens (Human)" 1.60446 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 1.60424 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 1.60261 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 1.59113 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 1.59112 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P14616 "Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSRR 3645; "Homo sapiens (Human)" 1.58448 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q5VT25 "Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPA 8476; "Homo sapiens (Human)" 1.58062 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.57512 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P42336 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)" "PI3/PI4-kinase family" PIK3CA 5290; "Homo sapiens (Human)" 1.5692 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 1.55998 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P04049 "RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" RAF1 5894; "Homo sapiens (Human)" 1.55922 17 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q96NX5 "Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I gamma) (CaM kinase IG) (CaM-KI gamma) (CaMKI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1G 57172; "Homo sapiens (Human)" 1.55185 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UBF8 "Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) (NPIK) (PI4K92)" "PI3/PI4-kinase family, Type III PI4K subfamily" PI4KB 5298; "Homo sapiens (Human)" 1.54954 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.54592 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q32MK0 "Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK3 91807; "Homo sapiens (Human)" 1.54563 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O14733 "Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (Stress-activated protein kinase kinase 4) (SAPK kinase 4) (SAPKK-4) (SAPKK4) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K7 5609; "Homo sapiens (Human)" 1.5452 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O43781 "Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1) (Regulatory erythroid kinase) (REDK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK3 8444; "Homo sapiens (Human)" 1.53688 18 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 1.52953 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.51643 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 1.49569 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13523 "Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" PRPF4B 8899; "Homo sapiens (Human)" 1.49319 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P22455 "Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR4 2264; "Homo sapiens (Human)" 1.48839 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P20794 "Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" MAK 4117; "Homo sapiens (Human)" 1.48016 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P78368 "Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G2 1455; "Homo sapiens (Human)" 1.4776 19 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UQ88 "Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 2) (Cell division protein kinase 11A) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK11A 728642; "Homo sapiens (Human)" 1.47003 20 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 1.46957 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.46321 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P42345 "Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)" "PI3/PI4-kinase family" MTOR 2475; "Homo sapiens (Human)" 1.45751 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P48729 "Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1 1452; "Homo sapiens (Human)" 1.45337 21 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 1.453 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 1.44733 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.44692 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8NEV4 "Myosin-IIIa (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3A 53904; "Homo sapiens (Human)" 1.43452 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P48736 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)" "PI3/PI4-kinase family" PIK3CG 5294; "Homo sapiens (Human)" 1.43229 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 1.42912 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.42783 22 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O14920 "Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKB 3551; "Homo sapiens (Human)" 1.41196 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 1.40972 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O43172 "U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4)" PRPF4 9128; "Homo sapiens (Human)" 1.40885 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P30291 "Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE1 7465; "Homo sapiens (Human)" 1.39385 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q15910 "Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.43) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)" "Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, EZ subfamily" EZH2 2146; "Homo sapiens (Human)" 1.39343 23 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8IW41 "MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAP-K5) (MAPKAPK-5) (MK-5) (MK5) (EC 2.7.11.1) (p38-regulated/activated protein kinase) (PRAK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MAPKAPK5 8550; "Homo sapiens (Human)" 1.39242 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q15208 "Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" STK38 11329; "Homo sapiens (Human)" 1.38873 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9P289 "Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK26 51765; "Homo sapiens (Human)" 1.3846 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q00534 "Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK6 1021; "Homo sapiens (Human)" 1.38116 24 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P42679 "Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" MATK 4145; "Homo sapiens (Human)" 1.38029 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 1.37889 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O00141 "Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK1 6446; "Homo sapiens (Human)" 1.36287 25 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9BX84 "Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6)" "Protein kinase superfamily, Alpha-type protein kinase family, ALPK subfamily; Transient receptor (TC 1.A.4) family, LTrpC subfamily, TRPM6 sub-subfamily" TRPM6 140803; "Homo sapiens (Human)" 1.35567 26 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q92772 "Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL2 8999; "Homo sapiens (Human)" 1.3508 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 1.34833 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13164 "Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK7 5598; "Homo sapiens (Human)" 1.34576 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9Y2H1 "Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" STK38L 23012; "Homo sapiens (Human)" 1.34046 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 1.3262 27 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 1.31489 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O15146 "Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)" "Protein kinase superfamily, Tyr protein kinase family" MUSK 4593; "Homo sapiens (Human)" 1.31215 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P19525 "Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK2 5610; "Homo sapiens (Human)" 1.31188 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9NUW8 "Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-)" "Tyrosyl-DNA phosphodiesterase family" TDP1 55775; "Homo sapiens (Human)" 1.30223 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9Y6E0 "Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK24 8428; "Homo sapiens (Human)" 1.29982 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 1.29953 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.29399 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UBE8 "Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" NLK 51701; "Homo sapiens (Human)" 1.288 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13233 "Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K1 4214; "Homo sapiens (Human)" 1.28626 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P28482 "Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK1 5594; "Homo sapiens (Human)" 1.27647 28 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P21127 "Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK11B 984; "Homo sapiens (Human)" 1.27556 29 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P0DMS8 "Adenosine receptor A3" "G-protein coupled receptor 1 family" ADORA3 140; "Homo sapiens (Human)" 1.2738 30 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P27986 "Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)" "PI3K p85 subunit family" PIK3R1 5295; "Homo sapiens (Human)" 1.27378 31 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9HC98 "Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6) (Protein kinase SID6-1512)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK6 10783; "Homo sapiens (Human)" 1.2606 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.25004 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q96Q40 "Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK15 65061; "Homo sapiens (Human)" 1.24713 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9BUB5 "MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK1 8569; "Homo sapiens (Human)" 1.22856 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P57058 "Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase MAK-V)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" HUNK 30811; "Homo sapiens (Human)" 1.22386 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q15569 "Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" TESK1 7016; "Homo sapiens (Human)" 1.22012 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9H2K2 "Poly [ADP-ribose] polymerase tankyrase-2 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (Poly [ADP-ribose] polymerase 5B) (Protein poly-ADP-ribosyltransferase tankyrase-2) (EC 2.4.2.-) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II) (Tankyrase-2) (TANK2) (Tankyrase-like protein) (Tankyrase-related protein)" TNKS2 80351; "Homo sapiens (Human)" 1.21991 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P49674 "Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1E 102800317;1454; "Homo sapiens (Human)" 1.21625 32 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 1.20744 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O00750 "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta)" "PI3/PI4-kinase family" PIK3C2B 5287; "Homo sapiens (Human)" 1.18871 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P41240 "Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" CSK 1445; "Homo sapiens (Human)" 1.18665 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O95382 "Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K6 9064; "Homo sapiens (Human)" 1.18598 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q16566 "Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK4 814; "Homo sapiens (Human)" 1.18321 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P31751 "RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC-PK-beta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT2 208; "Homo sapiens (Human)" 1.17568 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9UEW8 "STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK39 27347; "Homo sapiens (Human)" 1.17279 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O00329 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)" "PI3/PI4-kinase family" PIK3CD 5293; "Homo sapiens (Human)" 1.16724 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P37173 "TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR2 7048; "Homo sapiens (Human)" 1.16371 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P41743 "Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (PRKC-lambda/iota) (aPKC-lambda/iota) (nPKC-iota)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCI 5584; "Homo sapiens (Human)" 1.16104 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8TBX8 "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma)" PIP4K2C 79837; "Homo sapiens (Human)" 1.15348 33 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q96D53 "Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase 4) (Coenzyme Q protein 8B)" "Protein kinase superfamily, ADCK protein kinase family" COQ8B 79934; "Homo sapiens (Human)" 1.15133 34 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P53350 "Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK1 5347; "Homo sapiens (Human)" 1.14228 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8WU08 "Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32A 202374; "Homo sapiens (Human)" 1.13504 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P34947 "G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK5 2869; "Homo sapiens (Human)" 1.13234 35 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q01538 "Myelin transcription factor 1 (MyT1) (Myelin transcription factor I) (MyTI) (PLPB1) (Proteolipid protein-binding protein)" "MYT1 family" MYT1 4661; "Homo sapiens (Human)" 1.1293 36 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 1.11287 37 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 1.10901 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P49761 "Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK3 1198; "Homo sapiens (Human)" 1.10183 38 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P28335 "5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)" "G-protein coupled receptor 1 family" HTR2C 3358; "Homo sapiens (Human)" 1.09456 39 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9NRH2 "SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" SNRK 54861; "Homo sapiens (Human)" 1.09138 40 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q86UX6 "Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (Yet another novel kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32C 282974; "Homo sapiens (Human)" 1.08899 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8WXR4 "Myosin-IIIb (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3B 140469; "Homo sapiens (Human)" 1.07854 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 1.07644 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8NG66 "Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK11 79858; "Homo sapiens (Human)" 1.06336 41 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q96PF2 "Testis-specific serine/threonine-protein kinase 2 (TSK-2) (TSK2) (TSSK-2) (Testis-specific kinase 2) (EC 2.7.11.1) (DiGeorge syndrome protein G) (DGS-G) (Serine/threonine-protein kinase 22B)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK2 23617; "Homo sapiens (Human)" 1.05579 42 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9NY57 "Serine/threonine-protein kinase 32B (EC 2.7.11.1) (Yet another novel kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32B 55351; "Homo sapiens (Human)" 1.05387 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P51955 "Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK2 4751; "Homo sapiens (Human)" 1.0425 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9BQI3 "Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled repressor) (HCR) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Hemin-sensitive initiation factor 2-alpha kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK1 27102; "Homo sapiens (Human)" 1.03869 43 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9HCP0 "Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G1 53944; "Homo sapiens (Human)" 1.03435 44 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8N568 "Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin domain-containing protein 3B) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK2 166614; "Homo sapiens (Human)" 1.03224 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P29371 "Neuromedin-K receptor (NKR) (NK-3 receptor) (NK-3R) (Neurokinin B receptor) (Tachykinin receptor 3)" "G-protein coupled receptor 1 family" TACR3 6870; "Homo sapiens (Human)" 1.02881 45 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P54753 "Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) (EPH-like kinase 2) (Embryonic kinase 2) (EK2) (hEK2) (Tyrosine-protein kinase TYRO6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB3 2049; "Homo sapiens (Human)" 1.02879 46 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 1.01526 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9H4B4 "Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3) (Proliferation-related kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK3 1263; "Homo sapiens (Human)" 1.01494 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P49116 "Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TAK1) (Orphan nuclear receptor TR4) (Testicular receptor 4)" "Nuclear hormone receptor family, NR2 subfamily" NR2C2 7182; "Homo sapiens (Human)" 1.01384 47 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P29323 "Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB2 2048; "Homo sapiens (Human)" 1.01376 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O15075 "Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK1 9201; "Homo sapiens (Human)" 1.00884 48 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9Y5Y9 "Sodium channel protein type 10 subunit alpha (Peripheral nerve sodium channel 3) (PN3) (hPN3) (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8)" "Sodium channel (TC 1.A.1.10) family, Nav1.8/SCN10A subfamily" SCN10A 6336; "Homo sapiens (Human)" 0.988746 49 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P42338 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta)" "PI3/PI4-kinase family" PIK3CB 5291; "Homo sapiens (Human)" 0.978994 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9BVS4 "Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK2 55781; "Homo sapiens (Human)" 0.974281 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9Y5S2 "Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (CDC42BP-beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPB 9578; "Homo sapiens (Human)" 0.963225 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9Y243 "RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT3 10000; "Homo sapiens (Human)" 0.958426 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8IVW4 "Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine-protein kinase NKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL3 51265; "Homo sapiens (Human)" 0.955658 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 0.952005 50 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q6DT37 "Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (MRCKG) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPG 55561; "Homo sapiens (Human)" 0.948141 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8IY84 "Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" NIM1K 167359; "Homo sapiens (Human)" 0.937756 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P54756 "Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA5 2044; "Homo sapiens (Human)" 0.914521 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8TDX7 "Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK7 140609; "Homo sapiens (Human)" 0.909295 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8TD19 "Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK9 91754; "Homo sapiens (Human)" 0.893486 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P54764 "Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA4 2043; "Homo sapiens (Human)" 0.872111 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13705 "Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2B 93; "Homo sapiens (Human)" 0.868313 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q6P3R8 "Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase 5) (NimA-related protein kinase 5)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK5 341676; "Homo sapiens (Human)" 0.86005 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q96PY6 "Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK1 4750; "Homo sapiens (Human)" 0.855231 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q13873 "Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR2 659; "Homo sapiens (Human)" 0.83322 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P36894 "Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1A 657; "Homo sapiens (Human)" 0.832557 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9NYL2 "Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K20 51776; "Homo sapiens (Human)" 0.82388 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 0.798916 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9Y6R4 "Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K4 4216; "Homo sapiens (Human)" 0.783115 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 0.782296 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q8N752 "Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1L 122011; "Homo sapiens (Human)" 0.774935 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O43353 "Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK2 8767; "Homo sapiens (Human)" 0.709342 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P37023 "Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVRL1 94; "Homo sapiens (Human)" 0.673683 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O O95747 "Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" OXSR1 9943; "Homo sapiens (Human)" 0.657987 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P27037 "Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2A 92; "Homo sapiens (Human)" 0.581325 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P0C1S8 "Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) (Wee1B kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE2 494551; "Homo sapiens (Human)" 0.540133 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O Q9NRP7 "Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK36 27148; "Homo sapiens (Human)" 0.524354 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 0.428219 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P27361 "Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK3 5595; "Homo sapiens (Human)" 0.312107 Known 4 CHEMBL603469 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O P42858 "Huntingtin (Huntington disease protein) (HD protein)" "Huntingtin family" HTT 3064; "Homo sapiens (Human)" 0.294048 Known 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 O43614 "Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2)" "G-protein coupled receptor 1 family" HCRTR2 3062; "Homo sapiens (Human)" 2.89782 1 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P32239 "Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R)" "G-protein coupled receptor 1 family" CCKBR 887; "Homo sapiens (Human)" 2.89657 2 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P49286 "Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)" "G-protein coupled receptor 1 family" MTNR1B 4544; "Homo sapiens (Human)" 2.79087 3 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P46098 "5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)" "Ligand-gated ion channel (TC 1.A.9) family, 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily, HTR3A sub-subfamily" HTR3A 3359; "Homo sapiens (Human)" 2.78447 4 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 2.78438 5 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 Q13093 "Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47) (1-alkyl-2-acetylglycerophosphocholine esterase) (2-acetyl-1-alkylglycerophosphocholine esterase) (Group-VIIA phospholipase A2) (gVIIA-PLA2) (LDL-associated phospholipase A2) (LDL-PLA(2)) (PAF 2-acylhydrolase)" "AB hydrolase superfamily, Lipase family" PLA2G7 7941; "Homo sapiens (Human)" 2.64406 6 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P08908 "5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)" "G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamily" HTR1A 3350; "Homo sapiens (Human)" 2.51541 7 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 O00763 "Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)]" ACACB 32; "Homo sapiens (Human)" 2.51503 8 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P00918 "Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)" "Alpha-carbonic anhydrase family" CA2 760; "Homo sapiens (Human)" 2.48361 9 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 Q14703 "Membrane-bound transcription factor site-1 protease (EC 3.4.21.112) (Endopeptidase S1P) (Subtilisin/kexin-isozyme 1) (SKI-1)" "Peptidase S8 family" MBTPS1 8720; "Homo sapiens (Human)" 2.43323 10 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P30559 "Oxytocin receptor (OT-R)" "G-protein coupled receptor 1 family, Vasopressin/oxytocin receptor subfamily" OXTR 5021; "Homo sapiens (Human)" 2.4317 11 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P31644 "Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A) receptor subunit alpha-5)" "Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRA5 sub-subfamily" GABRA5 2558; "Homo sapiens (Human)" 2.36508 12 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P03372 "Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)" "Nuclear hormone receptor family, NR3 subfamily" ESR1 2099; "Homo sapiens (Human)" 2.16235 13 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P30536 "Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR)" "TspO/BZRP family" TSPO 706; "Homo sapiens (Human)" 2.12244 14 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 O43613 "Orexin receptor type 1 (Ox-1-R) (Ox1-R) (Ox1R) (Hypocretin receptor type 1)" "G-protein coupled receptor 1 family" HCRTR1 3061; "Homo sapiens (Human)" 2.09527 15 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P35372 "Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)" "G-protein coupled receptor 1 family" OPRM1 4988; "Homo sapiens (Human)" 2.06189 16 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P48039 "Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)" "G-protein coupled receptor 1 family" MTNR1A 4543; "Homo sapiens (Human)" 2.05268 17 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P34972 "Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)" "G-protein coupled receptor 1 family" CNR2 1269; "Homo sapiens (Human)" 1.99248 18 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 1.99232 19 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 O00748 "Cocaine esterase (EC 3.1.1.84) (Carboxylesterase 2) (CE-2) (hCE-2) (EC 3.1.1.1) (Methylumbelliferyl-acetate deacetylase 2) (EC 3.1.1.56)" "Type-B carboxylesterase/lipase family" CES2 8824; "Homo sapiens (Human)" 1.94075 20 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 Q99705 "Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein coupled receptor 24) (MCH-1R) (MCH1R) (MCHR) (SLC-1) (Somatostatin receptor-like protein)" "G-protein coupled receptor 1 family" MCHR1 2847; "Homo sapiens (Human)" 1.92231 21 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.89586 22 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P27487 "Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)]" "Peptidase S9B family, DPPIV subfamily" DPP4 1803; "Homo sapiens (Human)" 1.86406 23 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P23141 "Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) (Carboxylesterase 1) (CE-1) (hCE-1) (EC 3.1.1.1) (Cocaine carboxylesterase) (Egasyn) (HMSE) (Methylumbelliferyl-acetate deacetylase 1) (EC 3.1.1.56) (Monocyte/macrophage serine esterase) (Retinyl ester hydrolase) (REH) (Serine esterase 1) (Triacylglycerol hydrolase) (TGH)" "Type-B carboxylesterase/lipase family" CES1 1066; "Homo sapiens (Human)" 1.85649 24 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 Q13085 "Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (Acetyl-Coenzyme A carboxylase alpha) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)]" ACACA 31; "Homo sapiens (Human)" 1.84885 25 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 1.77735 26 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P28335 "5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)" "G-protein coupled receptor 1 family" HTR2C 3358; "Homo sapiens (Human)" 1.77295 27 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P14324 "Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase)" "FPP/GGPP synthase family" FDPS 2224; "Homo sapiens (Human)" 1.7518 28 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P08842 "Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase)" "Sulfatase family" STS 412; "Homo sapiens (Human)" 1.74633 29 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P07550 "Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB2 sub-subfamily" ADRB2 154; "Homo sapiens (Human)" 1.71836 30 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 Q14416 "Metabotropic glutamate receptor 2 (mGluR2)" "G-protein coupled receptor 3 family" GRM2 2912; "Homo sapiens (Human)" 1.71263 31 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P27815 "cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.53) (DPDE2) (PDE46)" "Cyclic nucleotide phosphodiesterase family, PDE4 subfamily" PDE4A 5141; "Homo sapiens (Human)" 1.67111 32 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P35348 "Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1A sub-subfamily" ADRA1A 148; "Homo sapiens (Human)" 1.66516 33 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 1.65918 34 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 Q15722 "Leukotriene B4 receptor 1 (LTB4-R 1) (LTB4-R1) (Chemoattractant receptor-like 1) (G-protein coupled receptor 16) (P2Y purinoceptor 7) (P2Y7)" "G-protein coupled receptor 1 family" LTB4R 1241; "Homo sapiens (Human)" 1.64667 35 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P10275 "Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)" "Nuclear hormone receptor family, NR3 subfamily" AR 367; "Homo sapiens (Human)" 1.63283 36 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 Q16790 "Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)" "Alpha-carbonic anhydrase family" CA9 768; "Homo sapiens (Human)" 1.60296 37 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P47211 "Galanin receptor type 1 (GAL1-R) (GALR-1)" "G-protein coupled receptor 1 family" GALR1 2587; "Homo sapiens (Human)" 1.60029 38 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P21554 "Cannabinoid receptor 1 (CB-R) (CB1) (CANN6)" "G-protein coupled receptor 1 family" CNR1 1268; "Homo sapiens (Human)" 1.59015 39 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P48067 "Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9)" "Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A9 subfamily" SLC6A9 6536; "Homo sapiens (Human)" 1.58578 40 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P08246 "Neutrophil elastase (EC 3.4.21.37) (Bone marrow serine protease) (Elastase-2) (Human leukocyte elastase) (HLE) (Medullasin) (PMN elastase)" "Peptidase S1 family, Elastase subfamily" ELANE 1991; "Homo sapiens (Human)" 1.58301 41 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P49810 "Presenilin-2 (PS-2) (EC 3.4.23.-) (AD3LP) (AD5) (E5-1) (STM-2) [Cleaved into: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit]" "Peptidase A22A family" PSEN2 5664; "Homo sapiens (Human)" 1.57109 42 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 Q9Y5Y4 "Prostaglandin D2 receptor 2 (Chemoattractant receptor-homologous molecule expressed on Th2 cells) (G-protein coupled receptor 44) (CD antigen CD294)" "G-protein coupled receptor 1 family" PTGDR2 11251; "Homo sapiens (Human)" 1.56249 43 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P04150 "Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)" "Nuclear hormone receptor family, NR3 subfamily" NR3C1 2908; "Homo sapiens (Human)" 1.54906 44 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P51681 "C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5) (CHEMR13) (HIV-1 fusion coreceptor) (CD antigen CD195)" "G-protein coupled receptor 1 family" CCR5 1234; "Homo sapiens (Human)" 1.5475 45 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 Q92731 "Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)" "Nuclear hormone receptor family, NR3 subfamily" ESR2 2100; "Homo sapiens (Human)" 1.5384 46 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 1.52975 47 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P00748 "Coagulation factor XII (EC 3.4.21.38) (Hageman factor) (HAF) [Cleaved into: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Coagulation factor XIIa light chain (Beta-factor XIIa part 2)]" "Peptidase S1 family" F12 2161; "Homo sapiens (Human)" 1.47973 48 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P08588 "Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB1 sub-subfamily" ADRB1 153; "Homo sapiens (Human)" 1.46938 49 5 CHEMBL4097778 CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)CC1CCS(=O)(=O)CC1 P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 1.46331 50 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 O43614 "Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2)" "G-protein coupled receptor 1 family" HCRTR2 3062; "Homo sapiens (Human)" 2.79122 1 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 2.78438 2 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 O00763 "Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)]" ACACB 32; "Homo sapiens (Human)" 2.51503 3 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P08842 "Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase)" "Sulfatase family" STS 412; "Homo sapiens (Human)" 2.44607 4 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 Q14703 "Membrane-bound transcription factor site-1 protease (EC 3.4.21.112) (Endopeptidase S1P) (Subtilisin/kexin-isozyme 1) (SKI-1)" "Peptidase S8 family" MBTPS1 8720; "Homo sapiens (Human)" 2.43323 5 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P49286 "Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)" "G-protein coupled receptor 1 family" MTNR1B 4544; "Homo sapiens (Human)" 2.36105 6 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P46098 "5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)" "Ligand-gated ion channel (TC 1.A.9) family, 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily, HTR3A sub-subfamily" HTR3A 3359; "Homo sapiens (Human)" 2.34982 7 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P08908 "5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)" "G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamily" HTR1A 3350; "Homo sapiens (Human)" 2.31557 8 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P48039 "Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)" "G-protein coupled receptor 1 family" MTNR1A 4543; "Homo sapiens (Human)" 2.27507 9 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P32239 "Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R)" "G-protein coupled receptor 1 family" CCKBR 887; "Homo sapiens (Human)" 2.26952 10 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P29275 "Adenosine receptor A2b" "G-protein coupled receptor 1 family" ADORA2B 136; "Homo sapiens (Human)" 2.24258 11 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P00918 "Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)" "Alpha-carbonic anhydrase family" CA2 760; "Homo sapiens (Human)" 2.15406 12 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P30536 "Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR)" "TspO/BZRP family" TSPO 706; "Homo sapiens (Human)" 2.14685 13 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 O43613 "Orexin receptor type 1 (Ox-1-R) (Ox1-R) (Ox1R) (Hypocretin receptor type 1)" "G-protein coupled receptor 1 family" HCRTR1 3061; "Homo sapiens (Human)" 2.10694 14 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 1.9972 15 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P34972 "Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)" "G-protein coupled receptor 1 family" CNR2 1269; "Homo sapiens (Human)" 1.99248 16 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P21554 "Cannabinoid receptor 1 (CB-R) (CB1) (CANN6)" "G-protein coupled receptor 1 family" CNR1 1268; "Homo sapiens (Human)" 1.95638 17 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 1.95208 18 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P30559 "Oxytocin receptor (OT-R)" "G-protein coupled receptor 1 family, Vasopressin/oxytocin receptor subfamily" OXTR 5021; "Homo sapiens (Human)" 1.94616 19 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P04150 "Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)" "Nuclear hormone receptor family, NR3 subfamily" NR3C1 2908; "Homo sapiens (Human)" 1.93817 20 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 Q99705 "Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein coupled receptor 24) (MCH-1R) (MCH1R) (MCHR) (SLC-1) (Somatostatin receptor-like protein)" "G-protein coupled receptor 1 family" MCHR1 2847; "Homo sapiens (Human)" 1.92231 21 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.89586 22 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P23141 "Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) (Carboxylesterase 1) (CE-1) (hCE-1) (EC 3.1.1.1) (Cocaine carboxylesterase) (Egasyn) (HMSE) (Methylumbelliferyl-acetate deacetylase 1) (EC 3.1.1.56) (Monocyte/macrophage serine esterase) (Retinyl ester hydrolase) (REH) (Serine esterase 1) (Triacylglycerol hydrolase) (TGH)" "Type-B carboxylesterase/lipase family" CES1 1066; "Homo sapiens (Human)" 1.85649 23 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 Q13085 "Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (Acetyl-Coenzyme A carboxylase alpha) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)]" ACACA 31; "Homo sapiens (Human)" 1.84885 24 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P03372 "Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)" "Nuclear hormone receptor family, NR3 subfamily" ESR1 2099; "Homo sapiens (Human)" 1.80187 25 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 Q15722 "Leukotriene B4 receptor 1 (LTB4-R 1) (LTB4-R1) (Chemoattractant receptor-like 1) (G-protein coupled receptor 16) (P2Y purinoceptor 7) (P2Y7)" "G-protein coupled receptor 1 family" LTB4R 1241; "Homo sapiens (Human)" 1.78287 26 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P35372 "Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)" "G-protein coupled receptor 1 family" OPRM1 4988; "Homo sapiens (Human)" 1.77988 27 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P28335 "5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)" "G-protein coupled receptor 1 family" HTR2C 3358; "Homo sapiens (Human)" 1.73065 28 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 O43683 "Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)" "Protein kinase superfamily, Ser/Thr protein kinase family, BUB1 subfamily" BUB1 699; "Homo sapiens (Human)" 1.67258 29 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P10275 "Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)" "Nuclear hormone receptor family, NR3 subfamily" AR 367; "Homo sapiens (Human)" 1.63283 30 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 1.61721 31 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 Q16790 "Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)" "Alpha-carbonic anhydrase family" CA9 768; "Homo sapiens (Human)" 1.5645 32 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 Q9Y5Y4 "Prostaglandin D2 receptor 2 (Chemoattractant receptor-homologous molecule expressed on Th2 cells) (G-protein coupled receptor 44) (CD antigen CD294)" "G-protein coupled receptor 1 family" PTGDR2 11251; "Homo sapiens (Human)" 1.56249 33 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P27487 "Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)]" "Peptidase S9B family, DPPIV subfamily" DPP4 1803; "Homo sapiens (Human)" 1.56034 34 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P08246 "Neutrophil elastase (EC 3.4.21.37) (Bone marrow serine protease) (Elastase-2) (Human leukocyte elastase) (HLE) (Medullasin) (PMN elastase)" "Peptidase S1 family, Elastase subfamily" ELANE 1991; "Homo sapiens (Human)" 1.55531 35 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 1.52695 36 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 Q13507 "Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (TRP-3) (hTrp-3) (hTrp3)" "Transient receptor (TC 1.A.4) family, STrpC subfamily, TRPC3 sub-subfamily" TRPC3 7222; "Homo sapiens (Human)" 1.50363 37 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P00748 "Coagulation factor XII (EC 3.4.21.38) (Hageman factor) (HAF) [Cleaved into: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Coagulation factor XIIa light chain (Beta-factor XIIa part 2)]" "Peptidase S1 family" F12 2161; "Homo sapiens (Human)" 1.49637 38 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P21917 "D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)" "G-protein coupled receptor 1 family" DRD4 1815; "Homo sapiens (Human)" 1.4482 39 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 Q9GZN0 "Probable G-protein coupled receptor 88 (Striatum-specific G-protein coupled receptor)" "G-protein coupled receptor 1 family" GPR88 54112; "Homo sapiens (Human)" 1.42086 40 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P07550 "Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB2 sub-subfamily" ADRB2 154; "Homo sapiens (Human)" 1.41052 41 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P07339 "Cathepsin D (EC 3.4.23.5) [Cleaved into: Cathepsin D light chain; Cathepsin D heavy chain]" "Peptidase A1 family" CTSD 1509; "Homo sapiens (Human)" 1.38933 42 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P35348 "Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1A sub-subfamily" ADRA1A 148; "Homo sapiens (Human)" 1.38014 43 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 Q96C86 "m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS)" "HIT family" DCPS 28960; "Homo sapiens (Human)" 1.37971 44 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P35368 "Alpha-1B adrenergic receptor (Alpha-1B adrenoreceptor) (Alpha-1B adrenoceptor)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1B sub-subfamily" ADRA1B 147; "Homo sapiens (Human)" 1.36024 45 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 Q99720 "Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding protein) (SR-BP) (Sigma 1-type opioid receptor) (SIG-1R) (Sigma1-receptor) (Sigma1R) (hSigmaR1)" "ERG2 family" SIGMAR1 10280; "Homo sapiens (Human)" 1.31639 46 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P30556 "Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1)" "G-protein coupled receptor 1 family" AGTR1 185; "Homo sapiens (Human)" 1.31411 47 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P42574 "Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]" "Peptidase C14A family" CASP3 836; "Homo sapiens (Human)" 1.30833 48 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 1.30032 49 6 CHEMBL4088216 CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 O=C1c2nn(cc2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Cc1ccccc1 P14867 "Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) receptor subunit alpha-1)" "Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRA1 sub-subfamily" GABRA1 2554; "Homo sapiens (Human)" 1.29051 50 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P34972 "Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)" "G-protein coupled receptor 1 family" CNR2 1269; "Homo sapiens (Human)" 3.27139 1 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 3.11641 2 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 O43614 "Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2)" "G-protein coupled receptor 1 family" HCRTR2 3062; "Homo sapiens (Human)" 3.06508 3 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 O43613 "Orexin receptor type 1 (Ox-1-R) (Ox1-R) (Ox1R) (Hypocretin receptor type 1)" "G-protein coupled receptor 1 family" HCRTR1 3061; "Homo sapiens (Human)" 2.98946 4 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 2.89836 5 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 2.83779 6 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 2.79774 7 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P49286 "Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)" "G-protein coupled receptor 1 family" MTNR1B 4544; "Homo sapiens (Human)" 2.7318 8 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P32239 "Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R)" "G-protein coupled receptor 1 family" CCKBR 887; "Homo sapiens (Human)" 2.66295 9 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P00918 "Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)" "Alpha-carbonic anhydrase family" CA2 760; "Homo sapiens (Human)" 2.66149 10 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P08842 "Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase)" "Sulfatase family" STS 412; "Homo sapiens (Human)" 2.64036 11 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 2.58034 12 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 Q14703 "Membrane-bound transcription factor site-1 protease (EC 3.4.21.112) (Endopeptidase S1P) (Subtilisin/kexin-isozyme 1) (SKI-1)" "Peptidase S8 family" MBTPS1 8720; "Homo sapiens (Human)" 2.43323 13 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P30536 "Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR)" "TspO/BZRP family" TSPO 706; "Homo sapiens (Human)" 2.3927 14 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P21554 "Cannabinoid receptor 1 (CB-R) (CB1) (CANN6)" "G-protein coupled receptor 1 family" CNR1 1268; "Homo sapiens (Human)" 2.2615 15 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P46098 "5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)" "Ligand-gated ion channel (TC 1.A.9) family, 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily, HTR3A sub-subfamily" HTR3A 3359; "Homo sapiens (Human)" 2.19683 16 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P30559 "Oxytocin receptor (OT-R)" "G-protein coupled receptor 1 family, Vasopressin/oxytocin receptor subfamily" OXTR 5021; "Homo sapiens (Human)" 2.12299 17 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P28335 "5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)" "G-protein coupled receptor 1 family" HTR2C 3358; "Homo sapiens (Human)" 2.04977 18 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 Q92731 "Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)" "Nuclear hormone receptor family, NR3 subfamily" ESR2 2100; "Homo sapiens (Human)" 2.0355 19 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P48039 "Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)" "G-protein coupled receptor 1 family" MTNR1A 4543; "Homo sapiens (Human)" 2.00365 20 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P03372 "Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)" "Nuclear hormone receptor family, NR3 subfamily" ESR1 2099; "Homo sapiens (Human)" 1.98393 21 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 O00748 "Cocaine esterase (EC 3.1.1.84) (Carboxylesterase 2) (CE-2) (hCE-2) (EC 3.1.1.1) (Methylumbelliferyl-acetate deacetylase 2) (EC 3.1.1.56)" "Type-B carboxylesterase/lipase family" CES2 8824; "Homo sapiens (Human)" 1.98369 22 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 1.97473 23 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P08908 "5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)" "G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamily" HTR1A 3350; "Homo sapiens (Human)" 1.96795 24 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 1.93842 25 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 Q15722 "Leukotriene B4 receptor 1 (LTB4-R 1) (LTB4-R1) (Chemoattractant receptor-like 1) (G-protein coupled receptor 16) (P2Y purinoceptor 7) (P2Y7)" "G-protein coupled receptor 1 family" LTB4R 1241; "Homo sapiens (Human)" 1.93161 26 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P41145 "Kappa-type opioid receptor (K-OR-1) (KOR-1)" "G-protein coupled receptor 1 family" OPRK1 4986; "Homo sapiens (Human)" 1.88111 27 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P30556 "Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1)" "G-protein coupled receptor 1 family" AGTR1 185; "Homo sapiens (Human)" 1.85657 28 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P23141 "Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) (Carboxylesterase 1) (CE-1) (hCE-1) (EC 3.1.1.1) (Cocaine carboxylesterase) (Egasyn) (HMSE) (Methylumbelliferyl-acetate deacetylase 1) (EC 3.1.1.56) (Monocyte/macrophage serine esterase) (Retinyl ester hydrolase) (REH) (Serine esterase 1) (Triacylglycerol hydrolase) (TGH)" "Type-B carboxylesterase/lipase family" CES1 1066; "Homo sapiens (Human)" 1.84854 29 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 O43683 "Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)" "Protein kinase superfamily, Ser/Thr protein kinase family, BUB1 subfamily" BUB1 699; "Homo sapiens (Human)" 1.81914 30 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P00748 "Coagulation factor XII (EC 3.4.21.38) (Hageman factor) (HAF) [Cleaved into: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Coagulation factor XIIa light chain (Beta-factor XIIa part 2)]" "Peptidase S1 family" F12 2161; "Homo sapiens (Human)" 1.78064 31 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P27487 "Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)]" "Peptidase S9B family, DPPIV subfamily" DPP4 1803; "Homo sapiens (Human)" 1.75602 32 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 Q16790 "Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)" "Alpha-carbonic anhydrase family" CA9 768; "Homo sapiens (Human)" 1.73598 33 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P35368 "Alpha-1B adrenergic receptor (Alpha-1B adrenoreceptor) (Alpha-1B adrenoceptor)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1B sub-subfamily" ADRA1B 147; "Homo sapiens (Human)" 1.72944 34 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P08246 "Neutrophil elastase (EC 3.4.21.37) (Bone marrow serine protease) (Elastase-2) (Human leukocyte elastase) (HLE) (Medullasin) (PMN elastase)" "Peptidase S1 family, Elastase subfamily" ELANE 1991; "Homo sapiens (Human)" 1.71221 35 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P35348 "Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1A sub-subfamily" ADRA1A 148; "Homo sapiens (Human)" 1.71106 36 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P00742 "Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]" "Peptidase S1 family" F10 2159; "Homo sapiens (Human)" 1.69052 37 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P07550 "Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB2 sub-subfamily" ADRB2 154; "Homo sapiens (Human)" 1.64042 38 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 Q13507 "Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (TRP-3) (hTrp-3) (hTrp3)" "Transient receptor (TC 1.A.4) family, STrpC subfamily, TRPC3 sub-subfamily" TRPC3 7222; "Homo sapiens (Human)" 1.63851 39 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 Q12809 "Potassium voltage-gated channel subfamily H member 2 (Eag homolog) (Ether-a-go-go-related gene potassium channel 1) (ERG-1) (Eag-related protein 1) (Ether-a-go-go-related protein 1) (H-ERG) (hERG-1) (hERG1) (Voltage-gated potassium channel subunit Kv11.1)" "Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.1/KCNH2 sub-subfamily" KCNH2 3757; "Homo sapiens (Human)" 1.63504 40 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P31645 "Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)" "Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamily" SLC6A4 6532; "Homo sapiens (Human)" 1.62621 41 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P43681 "Neuronal acetylcholine receptor subunit alpha-4" "Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Alpha-4/CHRNA4 sub-subfamily" CHRNA4 1137; "Homo sapiens (Human)" 1.58346 42 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P52732 "Kinesin-like protein KIF11 (Kinesin-like protein 1) (Kinesin-like spindle protein HKSP) (Kinesin-related motor protein Eg5) (Thyroid receptor-interacting protein 5) (TR-interacting protein 5) (TRIP-5)" "TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, BimC subfamily" KIF11 3832; "Homo sapiens (Human)" 1.57578 43 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P32238 "Cholecystokinin receptor type A (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R)" "G-protein coupled receptor 1 family" CCKAR 886; "Homo sapiens (Human)" 1.55757 44 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 Q96C86 "m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS)" "HIT family" DCPS 28960; "Homo sapiens (Human)" 1.53876 45 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P34913 "Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]" "AB hydrolase superfamily, Epoxide hydrolase family" EPHX2 2053; "Homo sapiens (Human)" 1.53095 46 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 P07339 "Cathepsin D (EC 3.4.23.5) [Cleaved into: Cathepsin D light chain; Cathepsin D heavy chain]" "Peptidase A1 family" CTSD 1509; "Homo sapiens (Human)" 1.52953 47 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 Q9GZN0 "Probable G-protein coupled receptor 88 (Striatum-specific G-protein coupled receptor)" "G-protein coupled receptor 1 family" GPR88 54112; "Homo sapiens (Human)" 1.51948 48 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 Q99720 "Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding protein) (SR-BP) (Sigma 1-type opioid receptor) (SIG-1R) (Sigma1-receptor) (Sigma1R) (hSigmaR1)" "ERG2 family" SIGMAR1 10280; "Homo sapiens (Human)" 1.48834 49 7 CHEMBL4549667 CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 O=C1c2nn(c(c2CCN1[C@H]1COc2c(N(C1=O)C)cccc2)Br)Cc1ccccc1 Q13258 "Prostaglandin D2 receptor (PGD receptor) (PGD2 receptor) (Prostanoid DP receptor)" "G-protein coupled receptor 1 family" PTGDR 5729; "Homo sapiens (Human)" 1.48635 50 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 4.00904 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 3.76307 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 3.5761 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 3.15588 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 3.12273 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 3.00548 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 2.88619 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 2.86536 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 2.77027 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 2.74077 1 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 2.72475 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 2.70332 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 2.65621 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 2.64528 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 2.60443 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 2.57474 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 2.55623 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 2.55275 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 2.53491 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 2.53077 2 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 2.47879 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 2.47516 3 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 2.47398 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 2.4737 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 2.47076 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 2.35606 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 2.30172 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 2.29221 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 2.28968 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P53350 "Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK1 5347; "Homo sapiens (Human)" 2.25333 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 2.25138 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P50406 "5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)" "G-protein coupled receptor 1 family" HTR6 3362; "Homo sapiens (Human)" 2.22522 4 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P21860 "Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB3 2065; "Homo sapiens (Human)" 2.21641 5 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 2.21028 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 2.17946 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 2.15547 6 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 2.14458 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 2.14408 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 2.13501 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 2.12481 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 2.12471 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.1092 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 2.1088 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 2.09742 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13164 "Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK7 5598; "Homo sapiens (Human)" 2.09665 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 2.08396 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 2.0715 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 2.06436 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 2.05507 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9C098 "Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK3 85443; "Homo sapiens (Human)" 2.04235 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 2.0404 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 2.03824 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q96D53 "Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase 4) (Coenzyme Q protein 8B)" "Protein kinase superfamily, ADCK protein kinase family" COQ8B 79934; "Homo sapiens (Human)" 2.03294 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9NYY3 "Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) (Serine/threonine-protein kinase SNK) (hSNK) (Serum-inducible kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK2 10769; "Homo sapiens (Human)" 2.02516 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 2.02475 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q00537 "Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK17 5128; "Homo sapiens (Human)" 2.02361 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 2.01297 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 2.01277 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9P2K8 "eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK4 440275; "Homo sapiens (Human)" 2.00218 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 1.99752 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9BWU1 "Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK19 23097; "Homo sapiens (Human)" 1.97802 7 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q00526 "Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK3 1018; "Homo sapiens (Human)" 1.96131 8 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 1.95992 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 1.95974 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 1.95969 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 1.94968 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 1.93623 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.93332 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 1.9278 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P17252 "Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCA 5578; "Homo sapiens (Human)" 1.92306 9 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 1.92229 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 1.86016 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P14616 "Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSRR 3645; "Homo sapiens (Human)" 1.85156 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q96L34 "MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK4 57787; "Homo sapiens (Human)" 1.83351 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 1.82373 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 1.81939 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13705 "Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2B 93; "Homo sapiens (Human)" 1.81534 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q15759 "Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK11 5600; "Homo sapiens (Human)" 1.81461 10 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 1.80832 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 1.79978 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q15046 "Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)" "Class-II aminoacyl-tRNA synthetase family" KARS 3735; "Homo sapiens (Human)" 1.79622 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 1.78936 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 1.78821 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 1.7867 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 1.78107 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P53355 "Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK1 1612; "Homo sapiens (Human)" 1.76696 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 1.76631 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q52WX2 "Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" SBK1 388228; "Homo sapiens (Human)" 1.76587 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O14920 "Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKB 3551; "Homo sapiens (Human)" 1.76222 11 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 1.75504 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8N568 "Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin domain-containing protein 3B) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK2 166614; "Homo sapiens (Human)" 1.75235 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 1.73965 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 1.73931 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 1.73397 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O94921 "Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK14 5218; "Homo sapiens (Human)" 1.72654 12 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.72406 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q32MK0 "Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK3 91807; "Homo sapiens (Human)" 1.72249 13 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 1.71101 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.71066 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9UIK4 "Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK2 23604; "Homo sapiens (Human)" 1.7093 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 1.70609 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9BXA7 "Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK1B 83942; "Homo sapiens (Human)" 1.70609 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9NWT8 "Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, mitochondrial) (MRP-S38) (Mitochondrial small ribosomal subunit protein mS38)" "Mitochondrion-specific ribosomal protein mS38 family" AURKAIP1 54998; "Homo sapiens (Human)" 1.70073 14 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 1.6917 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13557 "Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2D 817; "Homo sapiens (Human)" 1.68724 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 1.67716 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P20794 "Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" MAK 4117; "Homo sapiens (Human)" 1.67289 15 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O75914 "Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK3 5063; "Homo sapiens (Human)" 1.66518 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 1.66292 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q00536 "Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK16 5127; "Homo sapiens (Human)" 1.66196 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.6589 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 1.65166 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.6404 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 1.62895 16 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O94768 "Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17B 9262; "Homo sapiens (Human)" 1.62259 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P49761 "Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK3 1198; "Homo sapiens (Human)" 1.62144 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 1.61811 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 1.61597 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 1.61497 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 1.61005 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 1.60255 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P37023 "Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVRL1 94; "Homo sapiens (Human)" 1.58824 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 1.587 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8TD08 "Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK15 225689; "Homo sapiens (Human)" 1.5813 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8TD19 "Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK9 91754; "Homo sapiens (Human)" 1.56959 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9P286 "Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK5 57144; "Homo sapiens (Human)" 1.5677 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 1.56067 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P04049 "RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" RAF1 5894; "Homo sapiens (Human)" 1.5597 17 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O15146 "Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)" "Protein kinase superfamily, Tyr protein kinase family" MUSK 4593; "Homo sapiens (Human)" 1.55121 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.55001 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 1.54795 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13555 "Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2G 818; "Homo sapiens (Human)" 1.5471 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q00534 "Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK6 1021; "Homo sapiens (Human)" 1.54409 18 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P05771 "Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCB 5579; "Homo sapiens (Human)" 1.53701 19 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.5348 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P0C1S8 "Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) (Wee1B kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE2 494551; "Homo sapiens (Human)" 1.53122 20 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P27448 "MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK3 4140; "Homo sapiens (Human)" 1.53071 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8N5S9 "Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK1 84254; "Homo sapiens (Human)" 1.51014 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P24723 "Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCH 5583; "Homo sapiens (Human)" 1.50943 21 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q02779 "Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K10 4294; "Homo sapiens (Human)" 1.50494 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P21917 "D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)" "G-protein coupled receptor 1 family" DRD4 1815; "Homo sapiens (Human)" 1.50346 22 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.50303 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O15111 "Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" CHUK 1147; "Homo sapiens (Human)" 1.50287 23 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9P0L2 "Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK1 4139; "Homo sapiens (Human)" 1.50212 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 1.49727 24 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.48687 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.47152 25 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 1.46919 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 1.46887 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 1.46663 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 1.46522 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 1.46446 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P30291 "Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE1 7465; "Homo sapiens (Human)" 1.46222 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 1.4603 26 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.45312 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 1.44811 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 1.44471 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P28482 "Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK1 5594; "Homo sapiens (Human)" 1.44064 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 1.43467 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9Y6E0 "Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK24 8428; "Homo sapiens (Human)" 1.43248 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 1.43097 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 1.42918 27 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 1.42465 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.42418 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 1.42327 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 1.41367 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P78362 "SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK2 6733; "Homo sapiens (Human)" 1.4122 28 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P37173 "TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR2 7048; "Homo sapiens (Human)" 1.4027 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8TDX7 "Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK7 140609; "Homo sapiens (Human)" 1.40186 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 1.3963 29 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P54756 "Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA5 2044; "Homo sapiens (Human)" 1.39364 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 1.38786 30 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 1.38658 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 1.38537 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P54753 "Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) (EPH-like kinase 2) (Embryonic kinase 2) (EK2) (hEK2) (Tyrosine-protein kinase TYRO6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB3 2049; "Homo sapiens (Human)" 1.38217 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9NYL2 "Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K20 51776; "Homo sapiens (Human)" 1.37672 31 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 1.37307 32 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P0C264 "Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family member 3) (Sugen kinase 110)" "Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamily" SBK3 100130827; "Homo sapiens (Human)" 1.37127 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 1.36842 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.36839 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 1.36764 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8IVW4 "Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine-protein kinase NKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL3 51265; "Homo sapiens (Human)" 1.354 33 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 1.35316 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9H4B4 "Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3) (Proliferation-related kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK3 1263; "Homo sapiens (Human)" 1.34846 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 1.34832 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q05513 "Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCZ 5590; "Homo sapiens (Human)" 1.34219 34 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q16816 "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG1 5260; "Homo sapiens (Human)" 1.3396 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P49674 "Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1E 102800317;1454; "Homo sapiens (Human)" 1.32766 35 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 1.31772 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13237 "cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG2 5593; "Homo sapiens (Human)" 1.31484 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q02763 "Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TEK 7010; "Homo sapiens (Human)" 1.31379 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q15139 "Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD1 5587; "Homo sapiens (Human)" 1.3087 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 1.30637 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P54646 "5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA2 5563; "Homo sapiens (Human)" 1.30464 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P51957 "Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK4 6787; "Homo sapiens (Human)" 1.29897 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 1.29578 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q92772 "Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL2 8999; "Homo sapiens (Human)" 1.29243 36 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P36896 "Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1B 91; "Homo sapiens (Human)" 1.29087 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8IW41 "MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAP-K5) (MAPKAPK-5) (MK-5) (MK5) (EC 2.7.11.1) (p38-regulated/activated protein kinase) (PRAK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MAPKAPK5 8550; "Homo sapiens (Human)" 1.29001 37 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P48736 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)" "PI3/PI4-kinase family" PIK3CG 5294; "Homo sapiens (Human)" 1.28852 38 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9HC98 "Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6) (Protein kinase SID6-1512)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK6 10783; "Homo sapiens (Human)" 1.28548 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 1.28547 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P22455 "Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR4 2264; "Homo sapiens (Human)" 1.28395 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q15831 "Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamily" STK11 6794; "Homo sapiens (Human)" 1.28291 39 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.28063 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.27212 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 1.2659 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13153 "Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK1 5058; "Homo sapiens (Human)" 1.26583 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 1.26092 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9Y2K2 "Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK3 23387; "Homo sapiens (Human)" 1.25849 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q96SB4 "SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK1 6732; "Homo sapiens (Human)" 1.25626 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q15569 "Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" TESK1 7016; "Homo sapiens (Human)" 1.2556 40 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O00311 "Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamily" CDC7 8317; "Homo sapiens (Human)" 1.25382 41 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.25336 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P08908 "5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)" "G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamily" HTR1A 3350; "Homo sapiens (Human)" 1.25297 42 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 1.25 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13976 "cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG1 5592; "Homo sapiens (Human)" 1.24352 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q96PF2 "Testis-specific serine/threonine-protein kinase 2 (TSK-2) (TSK2) (TSSK-2) (Testis-specific kinase 2) (EC 2.7.11.1) (DiGeorge syndrome protein G) (DGS-G) (Serine/threonine-protein kinase 22B)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK2 23617; "Homo sapiens (Human)" 1.24035 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P00374 "Dihydrofolate reductase (EC 1.5.1.3)" "Dihydrofolate reductase family" DHFR 1719; "Homo sapiens (Human)" 1.23616 43 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 1.23598 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8TBX8 "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma)" PIP4K2C 79837; "Homo sapiens (Human)" 1.22623 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 1.2249 44 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 1.22233 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 1.21672 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O14936 "Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; MAGUK family" CASK 8573; "Homo sapiens (Human)" 1.21261 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 1.20947 45 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q00535 "Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK5 1020; "Homo sapiens (Human)" 1.20421 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13177 "Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK2 5062; "Homo sapiens (Human)" 1.20409 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9Y463 "Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1B 9149; "Homo sapiens (Human)" 1.203 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9BX84 "Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6)" "Protein kinase superfamily, Alpha-type protein kinase family, ALPK subfamily; Transient receptor (TC 1.A.4) family, LTrpC subfamily, TRPM6 sub-subfamily" TRPM6 140803; "Homo sapiens (Human)" 1.20268 46 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9NRP7 "Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK36 27148; "Homo sapiens (Human)" 1.19919 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O15264 "Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK13 5603; "Homo sapiens (Human)" 1.1972 47 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 1.19617 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9BRS2 "Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK1 83732; "Homo sapiens (Human)" 1.19592 48 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P42336 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)" "PI3/PI4-kinase family" PIK3CA 5290; "Homo sapiens (Human)" 1.19228 49 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q15375 "Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA7 2045; "Homo sapiens (Human)" 1.19088 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P19525 "Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK2 5610; "Homo sapiens (Human)" 1.18489 50 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 1.18375 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 1.18362 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 1.17793 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 1.17595 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P36894 "Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1A 657; "Homo sapiens (Human)" 1.1735 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q96Q40 "Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK15 65061; "Homo sapiens (Human)" 1.17046 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.1514 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9Y2H9 "Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" MAST1 22983; "Homo sapiens (Human)" 1.14875 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P29323 "Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB2 2048; "Homo sapiens (Human)" 1.14735 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.1471 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8WU08 "Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32A 202374; "Homo sapiens (Human)" 1.14252 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 1.14218 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P45985 "Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K4 6416; "Homo sapiens (Human)" 1.14205 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9UQM7 "Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2A 815; "Homo sapiens (Human)" 1.14189 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 1.14125 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O15075 "Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK1 9201; "Homo sapiens (Human)" 1.1376 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O14730 "Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK3 8780; "Homo sapiens (Human)" 1.1328 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9UEE5 "Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17A 9263; "Homo sapiens (Human)" 1.12867 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q6XUX3 "Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)" "Protein kinase superfamily, Ser/Thr protein kinase family" DSTYK 25778; "Homo sapiens (Human)" 1.12203 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13627 "Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1A 1859; "Homo sapiens (Human)" 1.11086 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q7KZI7 "Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK2 2011; "Homo sapiens (Human)" 1.1056 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.09651 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.09535 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8TDC3 "Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK1 84446; "Homo sapiens (Human)" 1.09213 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8WXR4 "Myosin-IIIb (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3B 140469; "Homo sapiens (Human)" 1.08672 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9UEW8 "STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK39 27347; "Homo sapiens (Human)" 1.08117 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P36897 "TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR1 7046; "Homo sapiens (Human)" 1.07603 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9P289 "Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK26 51765; "Homo sapiens (Human)" 1.06621 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P42680 "Tyrosine-protein kinase Tec (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TEC 7006; "Homo sapiens (Human)" 1.06433 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q6DT37 "Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (MRCKG) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPG 55561; "Homo sapiens (Human)" 1.06268 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O96013 "Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK4 10298; "Homo sapiens (Human)" 1.05506 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 1.04991 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 1.04961 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q16566 "Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK4 814; "Homo sapiens (Human)" 1.0492 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q15835 "Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK1 6011; "Homo sapiens (Human)" 1.04655 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.04615 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 1.04107 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q16512 "Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN1 5585; "Homo sapiens (Human)" 1.0363 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q04759 "Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCQ 5588; "Homo sapiens (Human)" 1.03524 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 1.03312 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 1.0321 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 1.03005 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 1.02892 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 1.02851 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O95747 "Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" OXSR1 9943; "Homo sapiens (Human)" 1.02255 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 1.02109 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9NY57 "Serine/threonine-protein kinase 32B (EC 2.7.11.1) (Yet another novel kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32B 55351; "Homo sapiens (Human)" 1.02039 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P43403 "Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" ZAP70 7535; "Homo sapiens (Human)" 0.976776 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 0.970519 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 0.963359 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q14012 "Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1 8536; "Homo sapiens (Human)" 0.950981 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9Y5S2 "Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (CDC42BP-beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPB 9578; "Homo sapiens (Human)" 0.949954 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 0.94974 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8WTQ7 "Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK7 131890; "Homo sapiens (Human)" 0.949569 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 0.9429 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9NRH2 "SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" SNRK 54861; "Homo sapiens (Human)" 0.942687 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P51956 "Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (HSPK 36) (Never in mitosis A-related kinase 3) (NimA-related protein kinase 3)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK3 4752; "Homo sapiens (Human)" 0.939727 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O43353 "Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK2 8767; "Homo sapiens (Human)" 0.938567 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O75460 "Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]" "Protein kinase superfamily, Ser/Thr protein kinase family" ERN1 2081; "Homo sapiens (Human)" 0.92831 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9UBF8 "Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) (NPIK) (PI4K92)" "PI3/PI4-kinase family, Type III PI4K subfamily" PI4KB 5298; "Homo sapiens (Human)" 0.926215 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P54764 "Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA4 2043; "Homo sapiens (Human)" 0.907336 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P27037 "Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2A 92; "Homo sapiens (Human)" 0.886185 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 0.861329 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q09013 "Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) (DMPK) (Myotonic dystrophy protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" DMPK 1760; "Homo sapiens (Human)" 0.857513 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P53671 "LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK2 3985; "Homo sapiens (Human)" 0.855873 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P34947 "G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK5 2869; "Homo sapiens (Human)" 0.852924 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q99755 "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)" PIP5K1A 8394; "Homo sapiens (Human)" 0.849105 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 0.848537 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13523 "Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" PRPF4B 8899; "Homo sapiens (Human)" 0.845499 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q59H18 "Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" TNNI3K 100526835;51086; "Homo sapiens (Human)" 0.843138 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P57078 "Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK4 "Homo sapiens (Human)" 0.842203 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 0.837655 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P22694 "cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACB 5567; "Homo sapiens (Human)" 0.831752 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P52564 "Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6) (Stress-activated protein kinase kinase 3) (SAPK kinase 3) (SAPKK-3) (SAPKK3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K6 5608; "Homo sapiens (Human)" 0.822751 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P27361 "Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK3 5595; "Homo sapiens (Human)" 0.821099 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8IY84 "Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" NIM1K 167359; "Homo sapiens (Human)" 0.808886 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 0.804138 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P41240 "Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" CSK 1445; "Homo sapiens (Human)" 0.800388 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q05655 "Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCD 5580; "Homo sapiens (Human)" 0.795774 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P51955 "Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK2 4751; "Homo sapiens (Human)" 0.79213 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8NEV4 "Myosin-IIIa (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3A 53904; "Homo sapiens (Human)" 0.78376 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P53778 "Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK12 6300; "Homo sapiens (Human)" 0.756721 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q6ZN16 "Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K15 389840; "Homo sapiens (Human)" 0.731557 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O95835 "Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS1 9113; "Homo sapiens (Human)" 0.728438 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 0.723863 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 0.713492 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q86UX6 "Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (Yet another novel kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32C 282974; "Homo sapiens (Human)" 0.711188 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 0.683777 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8NI60 "Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (Coenzyme Q protein 8A) (aarF domain-containing protein kinase 3)" "Protein kinase superfamily, ADCK protein kinase family" COQ8A 56997; "Homo sapiens (Human)" 0.665257 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P51817 "cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) (Protein kinase X-linked) (Serine/threonine-protein kinase PRKX) (EC 2.7.11.1) (Protein kinase PKX1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKX 5613; "Homo sapiens (Human)" 0.659143 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8IWQ3 "Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 2) (BR serine/threonine-protein kinase 2) (Serine/threonine-protein kinase 29) (Serine/threonine-protein kinase SAD-A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK2 9024; "Homo sapiens (Human)" 0.643507 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8NFD2 "Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" ANKK1 255239; "Homo sapiens (Human)" 0.638169 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P42679 "Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" MATK 4145; "Homo sapiens (Human)" 0.636976 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q96NX5 "Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I gamma) (CaM kinase IG) (CaM-KI gamma) (CaMKI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1G 57172; "Homo sapiens (Human)" 0.635514 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9Y6R4 "Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K4 4216; "Homo sapiens (Human)" 0.620166 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9NRM7 "Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS2 26524; "Homo sapiens (Human)" 0.617385 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13873 "Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR2 659; "Homo sapiens (Human)" 0.582962 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8N752 "Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1L 122011; "Homo sapiens (Human)" 0.564591 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9NQU5 "Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) (PAK-6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK6 106821730;56924; "Homo sapiens (Human)" 0.562666 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q15208 "Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" STK38 11329; "Homo sapiens (Human)" 0.559751 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q5VT25 "Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPA 8476; "Homo sapiens (Human)" 0.546515 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C P57058 "Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase MAK-V)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" HUNK 30811; "Homo sapiens (Human)" 0.539351 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 0.536623 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9Y2H1 "Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" STK38L 23012; "Homo sapiens (Human)" 0.496741 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 0.496439 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13554 "Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2B 816; "Homo sapiens (Human)" 0.461061 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q13233 "Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K1 4214; "Homo sapiens (Human)" 0.429153 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C Q02156 "Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCE 5581; "Homo sapiens (Human)" 0.425676 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O00506 "Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK25 10494; "Homo sapiens (Human)" 0.334537 Known 8 CHEMBL509032 COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 COc1cc(ccc1Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)C(C)C)Cl)N1CCC(CC1)N1CCN(CC1)C O95382 "Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K6 9064; "Homo sapiens (Human)" 0.204656 Known 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P27986 "Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)" "PI3K p85 subunit family" PIK3R1 5295; "Homo sapiens (Human)" 4.14869 1 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P47869 "Gamma-aminobutyric acid receptor subunit alpha-2 (GABA(A) receptor subunit alpha-2)" "Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRA2 sub-subfamily" GABRA2 2555; "Homo sapiens (Human)" 3.5727 2 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P31644 "Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A) receptor subunit alpha-5)" "Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRA5 sub-subfamily" GABRA5 2558; "Homo sapiens (Human)" 3.22058 3 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P34903 "Gamma-aminobutyric acid receptor subunit alpha-3 (GABA(A) receptor subunit alpha-3)" "Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRA3 sub-subfamily" GABRA3 2556; "Homo sapiens (Human)" 3.12513 4 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P30536 "Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR)" "TspO/BZRP family" TSPO 706; "Homo sapiens (Human)" 2.95272 5 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q15059 "Bromodomain-containing protein 3 (RING3-like protein)" BRD3 8019; "Homo sapiens (Human)" 2.83505 Known 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P14867 "Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) receptor subunit alpha-1)" "Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRA1 sub-subfamily" GABRA1 2554; "Homo sapiens (Human)" 2.38322 6 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P25440 "Bromodomain-containing protein 2 (O27.1.1) (Really interesting new gene 3 protein)" BRD2 6046; "Homo sapiens (Human)" 2.29132 Known 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P53350 "Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK1 5347; "Homo sapiens (Human)" 2.21743 7 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q07343 "cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.53) (DPDE4) (PDE32)" "Cyclic nucleotide phosphodiesterase family, PDE4 subfamily" PDE4B 5142; "Homo sapiens (Human)" 2.21662 8 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC O75376 "Nuclear receptor corepressor 1 (N-CoR) (N-CoR1)" "N-CoR nuclear receptor corepressors family" NCOR1 9611; "Homo sapiens (Human)" 2.13982 9 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P42338 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta)" "PI3/PI4-kinase family" PIK3CB 5291; "Homo sapiens (Human)" 2.07792 10 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P55201 "Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140)" BRPF1 7862; "Homo sapiens (Human)" 2.07553 11 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC O60885 "Bromodomain-containing protein 4 (Protein HUNK1)" BRD4 23476; "Homo sapiens (Human)" 2.06643 Known 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q58F21 "Bromodomain testis-specific protein (Cancer/testis antigen 9) (CT9) (RING3-like protein)" BRDT 676; "Homo sapiens (Human)" 2.01664 12 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q09472 "Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)" EP300 2033; "Homo sapiens (Human)" 1.88188 13 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P29275 "Adenosine receptor A2b" "G-protein coupled receptor 1 family" ADORA2B 136; "Homo sapiens (Human)" 1.86687 14 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC O00329 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)" "PI3/PI4-kinase family" PIK3CD 5293; "Homo sapiens (Human)" 1.84255 15 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 1.75217 16 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P25105 "Platelet-activating factor receptor (PAF-R) (PAFr)" "G-protein coupled receptor 1 family" PTAFR 5724; "Homo sapiens (Human)" 1.69092 17 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q92793 "CREB-binding protein (EC 2.3.1.48)" CREBBP 1387; "Homo sapiens (Human)" 1.68189 18 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q969S8 "Polyamine deacetylase HDAC10 (EC 3.5.1.48) (EC 3.5.1.62) (Histone deacetylase 10) (HD10)" "Histone deacetylase family, HD type 2 subfamily" HDAC10 83933; "Homo sapiens (Human)" 1.60916 19 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q6PL18 "ATPase family AAA domain-containing protein 2 (EC 3.6.1.3) (AAA nuclear coregulator cancer-associated protein) (ANCCA)" "AAA ATPase family" ATAD2 29028; "Homo sapiens (Human)" 1.53361 20 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P49286 "Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)" "G-protein coupled receptor 1 family" MTNR1B 4544; "Homo sapiens (Human)" 1.5047 21 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P48736 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)" "PI3/PI4-kinase family" PIK3CG 5294; "Homo sapiens (Human)" 1.44253 22 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q9UKV0 "Histone deacetylase 9 (HD9) (EC 3.5.1.98) (Histone deacetylase 7B) (HD7) (HD7b) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR)" "Histone deacetylase family, HD type 2 subfamily" HDAC9 9734; "Homo sapiens (Human)" 1.40709 23 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P42336 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)" "PI3/PI4-kinase family" PIK3CA 5290; "Homo sapiens (Human)" 1.36314 24 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q9H4B4 "Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3) (Proliferation-related kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK3 1263; "Homo sapiens (Human)" 1.33063 25 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC O00750 "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta)" "PI3/PI4-kinase family" PIK3C2B 5287; "Homo sapiens (Human)" 1.2468 26 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q9NPI1 "Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1)" BRD7 29117; "Homo sapiens (Human)" 1.22714 27 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q9H8M2 "Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS-40.8)" BRD9 65980; "Homo sapiens (Human)" 1.18873 28 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q9BXF3 "Cat eye syndrome critical region protein 2" CECR2 27443; "Homo sapiens (Human)" 1.18859 29 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q92769 "Histone deacetylase 2 (HD2) (EC 3.5.1.98)" "Histone deacetylase family, HD type 1 subfamily" HDAC2 3066; "Homo sapiens (Human)" 1.14198 30 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q96DB2 "Histone deacetylase 11 (HD11) (EC 3.5.1.98)" "Histone deacetylase family" HDAC11 79885; "Homo sapiens (Human)" 1.13267 31 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P28335 "5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)" "G-protein coupled receptor 1 family" HTR2C 3358; "Homo sapiens (Human)" 1.1265 32 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P78527 "DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)" "PI3/PI4-kinase family" PRKDC 5591; "Homo sapiens (Human)" 1.1171 33 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P51532 "Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)" "SNF2/RAD54 helicase family" SMARCA4 6597; "Homo sapiens (Human)" 1.07458 34 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q13547 "Histone deacetylase 1 (HD1) (EC 3.5.1.98)" "Histone deacetylase family, HD type 1 subfamily" HDAC1 3065; "Homo sapiens (Human)" 1.07046 35 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P34913 "Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]" "AB hydrolase superfamily, Epoxide hydrolase family" EPHX2 2053; "Homo sapiens (Human)" 1.03898 36 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 1.00939 37 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q8WUI4 "Histone deacetylase 7 (HD7) (EC 3.5.1.98) (Histone deacetylase 7A) (HD7a)" "Histone deacetylase family, HD type 2 subfamily" HDAC7 51564; "Homo sapiens (Human)" 0.9525 38 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC O15379 "Histone deacetylase 3 (HD3) (EC 3.5.1.98) (RPD3-2) (SMAP45)" "Histone deacetylase family, HD type 1 subfamily" HDAC3 8841; "Homo sapiens (Human)" 0.939068 39 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 0.914705 40 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P48039 "Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)" "G-protein coupled receptor 1 family" MTNR1A 4543; "Homo sapiens (Human)" 0.883042 41 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC O76074 "cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)" "Cyclic nucleotide phosphodiesterase family" PDE5A 8654; "Homo sapiens (Human)" 0.871578 42 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC O15164 "Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (RING-type E3 ubiquitin transferase TIF1-alpha) (Tripartite motif-containing protein 24)" TRIM24 8805; "Homo sapiens (Human)" 0.862974 43 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q9UQL6 "Histone deacetylase 5 (HD5) (EC 3.5.1.98) (Antigen NY-CO-9)" "Histone deacetylase family, HD type 2 subfamily" HDAC5 10014; "Homo sapiens (Human)" 0.845938 44 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P00918 "Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)" "Alpha-carbonic anhydrase family" CA2 760; "Homo sapiens (Human)" 0.840309 45 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P31213 "3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.1.22) (5 alpha-SR2) (SR type 2) (Steroid 5-alpha-reductase 2) (S5AR 2) (Type II 5-alpha reductase)" "Steroid 5-alpha reductase family" SRD5A2 6716; "Homo sapiens (Human)" 0.831272 46 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q9BY41 "Histone deacetylase 8 (HD8) (EC 3.5.1.98)" "Histone deacetylase family, HD type 1 subfamily" HDAC8 55869; "Homo sapiens (Human)" 0.795963 47 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P42345 "Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)" "PI3/PI4-kinase family" MTOR 2475; "Homo sapiens (Human)" 0.789223 48 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC P56524 "Histone deacetylase 4 (HD4) (EC 3.5.1.98)" "Histone deacetylase family, HD type 2 subfamily" HDAC4 9759; "Homo sapiens (Human)" 0.780073 49 9 CHEMBL1232461 CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 0.779275 50 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 3.21555 1 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 3.03333 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 3.01741 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 2.83976 2 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 2.83108 3 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 2.64484 4 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 2.63224 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 2.59886 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 2.57559 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 2.45479 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9NYL2 "Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K20 51776; "Homo sapiens (Human)" 2.40117 5 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 2.36408 6 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O76039 "Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL5 6792; "Homo sapiens (Human)" 2.27604 7 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 2.25815 8 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 2.24719 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 2.20743 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 2.19531 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q00537 "Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK17 5128; "Homo sapiens (Human)" 2.18934 9 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 2.18881 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 2.17482 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 2.17362 10 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 2.16438 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 2.15467 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q00536 "Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK16 5127; "Homo sapiens (Human)" 2.10991 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.08496 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 2.0104 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 2.00128 11 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O14920 "Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKB 3551; "Homo sapiens (Human)" 1.964 12 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 1.95633 13 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 1.9513 14 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 1.95099 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.90551 15 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 1.90512 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 1.89987 16 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 1.88084 17 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 1.88063 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 1.88032 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 1.87646 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 1.84297 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 1.83492 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 1.83391 18 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 1.83319 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q96Q40 "Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK15 65061; "Homo sapiens (Human)" 1.83126 19 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 1.82233 20 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 1.81738 21 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 1.79969 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.78818 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P54756 "Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA5 2044; "Homo sapiens (Human)" 1.78372 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 1.77818 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 1.77679 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q13976 "cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG1 5592; "Homo sapiens (Human)" 1.7545 22 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 1.75188 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 1.74779 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9UQ88 "Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 2) (Cell division protein kinase 11A) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK11A 728642; "Homo sapiens (Human)" 1.74196 23 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q15375 "Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA7 2045; "Homo sapiens (Human)" 1.74139 24 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.7365 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9Y463 "Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1B 9149; "Homo sapiens (Human)" 1.71777 25 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P78368 "Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G2 1455; "Homo sapiens (Human)" 1.71376 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 1.71212 26 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 1.71106 27 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.70471 28 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 1.7007 29 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 1.69616 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q8TD08 "Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK15 225689; "Homo sapiens (Human)" 1.6922 30 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P54646 "5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA2 5563; "Homo sapiens (Human)" 1.69033 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q00535 "Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK5 1020; "Homo sapiens (Human)" 1.68504 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 1.66685 31 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 1.66444 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 1.66232 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 1.65743 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 1.65135 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 1.64454 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 1.64408 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 1.63849 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 1.63816 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P21127 "Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK11B 984; "Homo sapiens (Human)" 1.63365 32 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 1.63037 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9UEE5 "Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17A 9263; "Homo sapiens (Human)" 1.62111 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 1.61924 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 1.61764 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.61472 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P29323 "Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB2 2048; "Homo sapiens (Human)" 1.60164 33 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 1.59666 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q13237 "cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG2 5593; "Homo sapiens (Human)" 1.59452 34 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 1.58937 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.58594 35 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.58206 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q99755 "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)" PIP5K1A 8394; "Homo sapiens (Human)" 1.58024 36 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.57667 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P31751 "RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC-PK-beta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT2 208; "Homo sapiens (Human)" 1.5706 37 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 1.56513 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 1.56359 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 1.54578 38 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 1.54192 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 1.53051 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.52711 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.52243 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 1.52147 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 1.51642 39 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 1.51358 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.5122 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 1.50321 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q32MK0 "Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK3 91807; "Homo sapiens (Human)" 1.49913 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q8WTQ7 "Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK7 131890; "Homo sapiens (Human)" 1.4916 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 1.49091 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 1.48709 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 1.48386 40 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 1.48218 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 1.48166 41 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.47807 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 1.45487 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 1.45409 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 1.45015 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.44723 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 1.44341 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9NWT8 "Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, mitochondrial) (MRP-S38) (Mitochondrial small ribosomal subunit protein mS38)" "Mitochondrion-specific ribosomal protein mS38 family" AURKAIP1 54998; "Homo sapiens (Human)" 1.43528 42 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 1.43195 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P54764 "Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA4 2043; "Homo sapiens (Human)" 1.42426 43 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q16816 "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG1 5260; "Homo sapiens (Human)" 1.42391 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 1.42355 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 1.41768 44 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 1.41621 45 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O00311 "Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamily" CDC7 8317; "Homo sapiens (Human)" 1.40948 46 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 1.40615 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.404 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 1.40036 47 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O43353 "Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK2 8767; "Homo sapiens (Human)" 1.39764 48 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q02156 "Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCE 5581; "Homo sapiens (Human)" 1.39615 49 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9BRS2 "Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK1 83732; "Homo sapiens (Human)" 1.39009 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 1.38479 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 1.38175 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q13546 "Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK1 8737; "Homo sapiens (Human)" 1.38036 50 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 1.37939 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 1.36779 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P14616 "Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSRR 3645; "Homo sapiens (Human)" 1.35527 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9BVS4 "Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK2 55781; "Homo sapiens (Human)" 1.34548 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O75914 "Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK3 5063; "Homo sapiens (Human)" 1.34102 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 1.33771 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 1.32958 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 1.3229 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 1.31958 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 1.31317 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.30888 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 1.3057 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 1.30522 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 1.29744 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q13523 "Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" PRPF4B 8899; "Homo sapiens (Human)" 1.28254 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 1.27933 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 1.27398 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P49674 "Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1E 102800317;1454; "Homo sapiens (Human)" 1.27246 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q52WX2 "Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" SBK1 388228; "Homo sapiens (Human)" 1.27176 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P22455 "Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR4 2264; "Homo sapiens (Human)" 1.25443 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 1.25232 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9P2K8 "eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK4 440275; "Homo sapiens (Human)" 1.25093 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 1.24072 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 1.23925 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 1.23668 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 1.23488 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.22852 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P78356 "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta)" PIP4K2B 8396; "Homo sapiens (Human)" 1.22654 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 1.22278 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P80370 "Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen 1 (FA1)]" DLK1 8788; "Homo sapiens (Human)" 1.21954 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O94921 "Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK14 5218; "Homo sapiens (Human)" 1.21014 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P57078 "Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK4 "Homo sapiens (Human)" 1.20621 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 1.19487 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 1.19014 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.18823 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.1813 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 1.18121 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 1.17194 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 1.16597 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.16435 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.15792 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P78362 "SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK2 6733; "Homo sapiens (Human)" 1.15589 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q13627 "Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1A 1859; "Homo sapiens (Human)" 1.14574 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 1.14219 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P48729 "Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1 1452; "Homo sapiens (Human)" 1.13852 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.1268 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P17252 "Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCA 5578; "Homo sapiens (Human)" 1.12522 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q07002 "Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK18 5129; "Homo sapiens (Human)" 1.12199 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 1.11513 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 1.115 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q15831 "Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamily" STK11 6794; "Homo sapiens (Human)" 1.10867 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 1.10295 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 1.08368 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q96SB4 "SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK1 6732; "Homo sapiens (Human)" 1.08294 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 1.08214 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q15835 "Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK1 6011; "Homo sapiens (Human)" 1.06644 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9Y2H9 "Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" MAST1 22983; "Homo sapiens (Human)" 1.05442 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q8N5S9 "Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK1 84254; "Homo sapiens (Human)" 1.05344 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q86YV6 "Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK4 340156; "Homo sapiens (Human)" 1.05237 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q13557 "Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2D 817; "Homo sapiens (Human)" 1.04374 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 1.04332 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9P286 "Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK5 57144; "Homo sapiens (Human)" 1.03983 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9NRM7 "Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS2 26524; "Homo sapiens (Human)" 1.02826 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 1.02767 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.02355 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 1.01636 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9UEW8 "STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK39 27347; "Homo sapiens (Human)" 1.00787 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 1.0044 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 0.998007 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 0.993415 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 0.987108 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O94768 "Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17B 9262; "Homo sapiens (Human)" 0.985089 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O15111 "Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" CHUK 1147; "Homo sapiens (Human)" 0.964984 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P42679 "Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" MATK 4145; "Homo sapiens (Human)" 0.961777 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q6XUX3 "Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)" "Protein kinase superfamily, Ser/Thr protein kinase family" DSTYK 25778; "Homo sapiens (Human)" 0.958034 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 0.945944 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 0.945571 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P45985 "Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K4 6416; "Homo sapiens (Human)" 0.944117 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q15139 "Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD1 5587; "Homo sapiens (Human)" 0.941625 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 0.909249 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9Y6E0 "Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK24 8428; "Homo sapiens (Human)" 0.898144 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 0.885732 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O96013 "Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK4 10298; "Homo sapiens (Human)" 0.867932 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O43172 "U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4)" PRPF4 9128; "Homo sapiens (Human)" 0.860418 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 0.853882 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q92772 "Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL2 8999; "Homo sapiens (Human)" 0.846318 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 0.841236 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9H1R3 "Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK2 85366; "Homo sapiens (Human)" 0.834295 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9NRH2 "SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" SNRK 54861; "Homo sapiens (Human)" 0.824339 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9BUB5 "MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK1 8569; "Homo sapiens (Human)" 0.815841 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q96BR1 "Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK3 100533105;23678; "Homo sapiens (Human)" 0.801397 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P0C264 "Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family member 3) (Sugen kinase 110)" "Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamily" SBK3 100130827; "Homo sapiens (Human)" 0.783967 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 0.779909 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 0.75336 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P27448 "MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK3 4140; "Homo sapiens (Human)" 0.734065 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9C098 "Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK3 85443; "Homo sapiens (Human)" 0.719378 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P22303 "Acetylcholinesterase (AChE) (EC 3.1.1.7)" "Type-B carboxylesterase/lipase family" ACHE 43; "Homo sapiens (Human)" 0.712819 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q92630 "Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK2 8445; "Homo sapiens (Human)" 0.702962 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P57058 "Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase MAK-V)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" HUNK 30811; "Homo sapiens (Human)" 0.654082 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O95747 "Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" OXSR1 9943; "Homo sapiens (Human)" 0.65309 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q8NFD2 "Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" ANKK1 255239; "Homo sapiens (Human)" 0.635073 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q13164 "Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK7 5598; "Homo sapiens (Human)" 0.616871 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q8IY84 "Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" NIM1K 167359; "Homo sapiens (Human)" 0.608448 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O75460 "Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]" "Protein kinase superfamily, Ser/Thr protein kinase family" ERN1 2081; "Homo sapiens (Human)" 0.602268 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 0.601646 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9Y6M4 "Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G3 1456; "Homo sapiens (Human)" 0.590375 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q7KZI7 "Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK2 2011; "Homo sapiens (Human)" 0.586935 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q6ZN16 "Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K15 389840; "Homo sapiens (Human)" 0.586288 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9H2K2 "Poly [ADP-ribose] polymerase tankyrase-2 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (Poly [ADP-ribose] polymerase 5B) (Protein poly-ADP-ribosyltransferase tankyrase-2) (EC 2.4.2.-) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II) (Tankyrase-2) (TANK2) (Tankyrase-like protein) (Tankyrase-related protein)" TNKS2 80351; "Homo sapiens (Human)" 0.584448 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9UQM7 "Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2A 815; "Homo sapiens (Human)" 0.571856 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q96NX5 "Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I gamma) (CaM kinase IG) (CaM-KI gamma) (CaMKI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1G 57172; "Homo sapiens (Human)" 0.55985 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P53355 "Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK1 1612; "Homo sapiens (Human)" 0.557622 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9UIK4 "Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK2 23604; "Homo sapiens (Human)" 0.522616 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 0.515797 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9Y6R4 "Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K4 4216; "Homo sapiens (Human)" 0.510005 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q13555 "Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2G 818; "Homo sapiens (Human)" 0.48712 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 0.484341 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q15208 "Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" STK38 11329; "Homo sapiens (Human)" 0.482462 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 0.460775 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9NQU5 "Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) (PAK-6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK6 106821730;56924; "Homo sapiens (Human)" 0.454471 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q8NEV4 "Myosin-IIIa (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3A 53904; "Homo sapiens (Human)" 0.433616 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q9NYY3 "Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) (Serine/threonine-protein kinase SNK) (hSNK) (Serum-inducible kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK2 10769; "Homo sapiens (Human)" 0.430801 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P51955 "Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK2 4751; "Homo sapiens (Human)" 0.428223 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" P52564 "Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6) (Stress-activated protein kinase kinase 3) (SAPK kinase 3) (SAPKK-3) (SAPKK3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K6 5608; "Homo sapiens (Human)" 0.401292 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O00506 "Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK25 10494; "Homo sapiens (Human)" 0.321304 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" Q12809 "Potassium voltage-gated channel subfamily H member 2 (Eag homolog) (Ether-a-go-go-related gene potassium channel 1) (ERG-1) (Eag-related protein 1) (Ether-a-go-go-related protein 1) (H-ERG) (hERG-1) (hERG1) (Voltage-gated potassium channel subunit Kv11.1)" "Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.1/KCNH2 sub-subfamily" KCNH2 3757; "Homo sapiens (Human)" 0.22685 Known 10 CHEMBL535 "CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C" "CCN(CCNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2)CC" O15245 "Solute carrier family 22 member 1 (Organic cation transporter 1) (hOCT1)" "Major facilitator (TC 2.A.1) superfamily, Organic cation transporter (TC 2.A.1.19) family" SLC22A1 6580; "Homo sapiens (Human)" 0.163489 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 3.7909 1 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 3.48562 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 3.39565 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 3.24438 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 3.14681 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 3.07502 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 2.98064 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 2.74217 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 2.73071 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 2.67994 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 2.67391 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 2.66122 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 2.64098 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P21860 "Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB3 2065; "Homo sapiens (Human)" 2.61692 2 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 2.60443 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 2.59731 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 2.57573 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 2.57431 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 2.55244 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 2.51925 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 2.4996 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 2.48872 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 2.43773 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 2.4048 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 2.39763 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 2.3785 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 2.37265 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 2.36807 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 2.36268 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 2.35521 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 2.34444 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 2.34163 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 2.3389 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 2.33014 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 2.31776 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 2.30855 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 2.30661 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 2.29278 3 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 2.28864 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 2.25939 4 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9P2K8 "eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK4 440275; "Homo sapiens (Human)" 2.25628 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 2.24555 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 2.24272 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 2.22666 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 2.22064 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 2.207 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 2.19305 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 2.18318 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 2.17968 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O75914 "Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK3 5063; "Homo sapiens (Human)" 2.16876 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 2.16347 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 2.1452 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P51679 "C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) (K5-5) (CD antigen CD194)" "G-protein coupled receptor 1 family" CCR4 1233; "Homo sapiens (Human)" 2.14246 5 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 2.13965 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q13164 "Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK7 5598; "Homo sapiens (Human)" 2.13868 6 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 2.09861 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 2.08898 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 2.06747 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.06219 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 2.04661 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9C098 "Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK3 85443; "Homo sapiens (Human)" 2.04235 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 2.03824 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 2.03457 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 2.0276 7 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9NYY3 "Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) (Serine/threonine-protein kinase SNK) (hSNK) (Serum-inducible kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK2 10769; "Homo sapiens (Human)" 2.02516 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q00537 "Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK17 5128; "Homo sapiens (Human)" 2.02361 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 2.02131 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 2.01902 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 2.0144 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O00311 "Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamily" CDC7 8317; "Homo sapiens (Human)" 2.00931 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 1.99204 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.9904 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 1.98847 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 1.98806 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.986 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9BXA7 "Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK1B 83942; "Homo sapiens (Human)" 1.98458 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 1.97501 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q15375 "Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA7 2045; "Homo sapiens (Human)" 1.97426 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 1.96252 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 1.9581 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 1.9519 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 1.94898 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 1.94161 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.93333 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 1.93098 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q96D53 "Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase 4) (Coenzyme Q protein 8B)" "Protein kinase superfamily, ADCK protein kinase family" COQ8B 79934; "Homo sapiens (Human)" 1.91694 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 1.89539 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O15146 "Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)" "Protein kinase superfamily, Tyr protein kinase family" MUSK 4593; "Homo sapiens (Human)" 1.892 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P14616 "Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSRR 3645; "Homo sapiens (Human)" 1.85156 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 1.84872 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 1.84218 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q96L34 "MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK4 57787; "Homo sapiens (Human)" 1.83351 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 1.83174 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 1.82074 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 1.81862 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P24723 "Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCH 5583; "Homo sapiens (Human)" 1.81385 8 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 1.8052 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q00536 "Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK16 5127; "Homo sapiens (Human)" 1.79158 9 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 1.78294 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O94768 "Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17B 9262; "Homo sapiens (Human)" 1.78081 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 1.7696 10 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 1.76695 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q52WX2 "Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" SBK1 388228; "Homo sapiens (Human)" 1.76587 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.7547 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P53355 "Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK1 1612; "Homo sapiens (Human)" 1.75196 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8N5S9 "Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK1 84254; "Homo sapiens (Human)" 1.74074 11 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.73464 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 1.7256 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P29323 "Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB2 2048; "Homo sapiens (Human)" 1.72543 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 1.71587 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P42680 "Tyrosine-protein kinase Tec (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TEC 7006; "Homo sapiens (Human)" 1.71216 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 1.70469 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 1.69819 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9UIK4 "Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK2 23604; "Homo sapiens (Human)" 1.69107 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 1.68782 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 1.67474 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 1.67421 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 1.67407 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q16816 "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG1 5260; "Homo sapiens (Human)" 1.66954 12 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9Y2K2 "Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK3 23387; "Homo sapiens (Human)" 1.65735 13 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 1.65604 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 1.65017 14 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 1.64485 15 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O94921 "Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK14 5218; "Homo sapiens (Human)" 1.64014 16 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q00535 "Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK5 1020; "Homo sapiens (Human)" 1.6327 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 1.63142 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9NWT8 "Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, mitochondrial) (MRP-S38) (Mitochondrial small ribosomal subunit protein mS38)" "Mitochondrion-specific ribosomal protein mS38 family" AURKAIP1 54998; "Homo sapiens (Human)" 1.62743 17 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O14920 "Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKB 3551; "Homo sapiens (Human)" 1.62354 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P04049 "RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" RAF1 5894; "Homo sapiens (Human)" 1.61987 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q00526 "Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK3 1018; "Homo sapiens (Human)" 1.61659 18 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.61312 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 1.60776 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 1.60692 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 1.60569 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 1.60568 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P53671 "LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK2 3985; "Homo sapiens (Human)" 1.60451 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.60151 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P42338 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta)" "PI3/PI4-kinase family" PIK3CB 5291; "Homo sapiens (Human)" 1.59466 19 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.59049 20 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 1.58847 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O15111 "Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" CHUK 1147; "Homo sapiens (Human)" 1.58713 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 1.5869 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P54764 "Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA4 2043; "Homo sapiens (Human)" 1.58593 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8TD08 "Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK15 225689; "Homo sapiens (Human)" 1.5813 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P28482 "Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK1 5594; "Homo sapiens (Human)" 1.57644 21 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8TD19 "Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK9 91754; "Homo sapiens (Human)" 1.57067 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q13557 "Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2D 817; "Homo sapiens (Human)" 1.56919 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9P286 "Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK5 57144; "Homo sapiens (Human)" 1.5677 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 1.56067 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.55481 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 1.55 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q13627 "Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1A 1859; "Homo sapiens (Human)" 1.54023 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 1.53641 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 1.53406 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q02779 "Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K10 4294; "Homo sapiens (Human)" 1.53359 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 1.53343 22 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q13555 "Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2G 818; "Homo sapiens (Human)" 1.5303 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 1.52591 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 1.52182 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q02763 "Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TEK 7010; "Homo sapiens (Human)" 1.52169 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P37023 "Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVRL1 94; "Homo sapiens (Human)" 1.51099 23 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.51065 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.49626 24 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 1.49528 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.48458 25 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.4807 26 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q15759 "Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK11 5600; "Homo sapiens (Human)" 1.46842 27 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P17252 "Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCA 5578; "Homo sapiens (Human)" 1.46671 28 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.46389 29 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 1.46322 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q00532 "Cyclin-dependent kinase-like 1 (EC 2.7.11.22) (Protein kinase p42 KKIALRE) (Serine/threonine-protein kinase KKIALRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL1 8814; "Homo sapiens (Human)" 1.45978 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P0C1S8 "Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) (Wee1B kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE2 494551; "Homo sapiens (Human)" 1.44847 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.44513 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P48736 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)" "PI3/PI4-kinase family" PIK3CG 5294; "Homo sapiens (Human)" 1.44318 30 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 1.44312 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P22455 "Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR4 2264; "Homo sapiens (Human)" 1.43666 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 1.43574 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 1.43405 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P27448 "MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK3 4140; "Homo sapiens (Human)" 1.43269 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.42999 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.42915 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.41659 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q15569 "Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" TESK1 7016; "Homo sapiens (Human)" 1.40649 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 1.40551 31 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P53350 "Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK1 5347; "Homo sapiens (Human)" 1.4044 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P37173 "TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR2 7048; "Homo sapiens (Human)" 1.4027 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 1.40268 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 1.39284 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 1.38515 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 1.38087 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P54756 "Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA5 2044; "Homo sapiens (Human)" 1.37498 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P0C264 "Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family member 3) (Sugen kinase 110)" "Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamily" SBK3 100130827; "Homo sapiens (Human)" 1.37127 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9P0L2 "Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK1 4139; "Homo sapiens (Human)" 1.37025 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9Y5Y9 "Sodium channel protein type 10 subunit alpha (Peripheral nerve sodium channel 3) (PN3) (hPN3) (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8)" "Sodium channel (TC 1.A.1.10) family, Nav1.8/SCN10A subfamily" SCN10A 6336; "Homo sapiens (Human)" 1.35515 32 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 1.35 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.34877 33 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q13705 "Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2B 93; "Homo sapiens (Human)" 1.3463 34 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 1.3425 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8N568 "Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin domain-containing protein 3B) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK2 166614; "Homo sapiens (Human)" 1.34053 35 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P51955 "Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK2 4751; "Homo sapiens (Human)" 1.33965 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 1.33632 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 1.33045 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q07002 "Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK18 5129; "Homo sapiens (Human)" 1.32918 36 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P49761 "Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK3 1198; "Homo sapiens (Human)" 1.32343 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9BX84 "Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6)" "Protein kinase superfamily, Alpha-type protein kinase family, ALPK subfamily; Transient receptor (TC 1.A.4) family, LTrpC subfamily, TRPM6 sub-subfamily" TRPM6 140803; "Homo sapiens (Human)" 1.32147 37 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 1.31789 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9UBE8 "Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" NLK 51701; "Homo sapiens (Human)" 1.31495 38 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q13237 "cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG2 5593; "Homo sapiens (Human)" 1.31484 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P54753 "Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) (EPH-like kinase 2) (Embryonic kinase 2) (EK2) (hEK2) (Tyrosine-protein kinase TYRO6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB3 2049; "Homo sapiens (Human)" 1.31045 39 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q15139 "Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD1 5587; "Homo sapiens (Human)" 1.3087 40 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8TDX7 "Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK7 140609; "Homo sapiens (Human)" 1.3064 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q00534 "Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK6 1021; "Homo sapiens (Human)" 1.30553 41 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 1.29578 42 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P36896 "Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1B 91; "Homo sapiens (Human)" 1.29087 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P30291 "Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE1 7465; "Homo sapiens (Human)" 1.28279 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q92772 "Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL2 8999; "Homo sapiens (Human)" 1.28055 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 1.27739 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9NRP7 "Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK36 27148; "Homo sapiens (Human)" 1.27256 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.27117 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P25101 "Endothelin-1 receptor (Endothelin receptor type A) (ET-A) (ETA-R) (hET-AR)" "G-protein coupled receptor 1 family, Endothelin receptor subfamily, EDNRA sub-subfamily" EDNRA 1909; "Homo sapiens (Human)" 1.26426 43 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P51957 "Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK4 6787; "Homo sapiens (Human)" 1.26254 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 1.25913 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9HC98 "Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6) (Protein kinase SID6-1512)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK6 10783; "Homo sapiens (Human)" 1.25275 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P45985 "Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K4 6416; "Homo sapiens (Human)" 1.25218 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P41240 "Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" CSK 1445; "Homo sapiens (Human)" 1.2479 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P28845 "Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC 1.1.1.146) (11-beta-hydroxysteroid dehydrogenase 1) (11-DH) (11-beta-HSD1) (Short chain dehydrogenase/reductase family 26C member 1)" "Short-chain dehydrogenases/reductases (SDR) family" HSD11B1 3290; "Homo sapiens (Human)" 1.24423 44 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 1.24014 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q59H18 "Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" TNNI3K 100526835;51086; "Homo sapiens (Human)" 1.23893 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 1.23249 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P78356 "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta)" PIP4K2B 8396; "Homo sapiens (Human)" 1.23111 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O15075 "Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK1 9201; "Homo sapiens (Human)" 1.23031 45 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 1.22944 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P62937 "Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]" "Cyclophilin-type PPIase family, PPIase A subfamily" PPIA 5478; "Homo sapiens (Human)" 1.21888 46 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8IW41 "MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAP-K5) (MAPKAPK-5) (MK-5) (MK5) (EC 2.7.11.1) (p38-regulated/activated protein kinase) (PRAK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MAPKAPK5 8550; "Homo sapiens (Human)" 1.21593 47 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 1.21302 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P27986 "Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)" "PI3K p85 subunit family" PIK3R1 5295; "Homo sapiens (Human)" 1.21299 48 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P19525 "Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK2 5610; "Homo sapiens (Human)" 1.20911 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 1.20152 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 1.19617 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9BRS2 "Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK1 83732; "Homo sapiens (Human)" 1.19592 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 1.19523 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q6P3R8 "Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase 5) (NimA-related protein kinase 5)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK5 341676; "Homo sapiens (Human)" 1.19229 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P48729 "Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1 1452; "Homo sapiens (Human)" 1.17976 49 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 1.17799 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P54646 "5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA2 5563; "Homo sapiens (Human)" 1.17087 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 1.16039 50 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.14788 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8TBX8 "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma)" PIP4K2C 79837; "Homo sapiens (Human)" 1.14614 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 1.13913 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.1367 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O14730 "Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK3 8780; "Homo sapiens (Human)" 1.1328 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9UEE5 "Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17A 9263; "Homo sapiens (Human)" 1.12867 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 1.12737 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8WU08 "Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32A 202374; "Homo sapiens (Human)" 1.12311 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 1.11778 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q7KZI7 "Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK2 2011; "Homo sapiens (Human)" 1.1056 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9Y6R4 "Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K4 4216; "Homo sapiens (Human)" 1.10343 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9UQM7 "Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2A 815; "Homo sapiens (Human)" 1.09511 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.09267 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q13177 "Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK2 5062; "Homo sapiens (Human)" 1.0819 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O00329 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)" "PI3/PI4-kinase family" PIK3CD 5293; "Homo sapiens (Human)" 1.07863 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P36897 "TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR1 7046; "Homo sapiens (Human)" 1.07603 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q86YV6 "Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK4 340156; "Homo sapiens (Human)" 1.06373 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9BUB5 "MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK1 8569; "Homo sapiens (Human)" 1.06283 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9UKI8 "Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" TLK1 9874; "Homo sapiens (Human)" 1.06095 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q15835 "Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK1 6011; "Homo sapiens (Human)" 1.04655 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 1.04552 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9H4B4 "Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3) (Proliferation-related kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK3 1263; "Homo sapiens (Human)" 1.04444 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q16512 "Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN1 5585; "Homo sapiens (Human)" 1.0363 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 1.03176 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 1.02851 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O96013 "Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK4 10298; "Homo sapiens (Human)" 1.01491 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O43353 "Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK2 8767; "Homo sapiens (Human)" 1.01038 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8WTQ7 "Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK7 131890; "Homo sapiens (Human)" 0.998827 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q96PY6 "Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK1 4750; "Homo sapiens (Human)" 0.994728 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 0.986342 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P43403 "Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" ZAP70 7535; "Homo sapiens (Human)" 0.976776 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 0.970519 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q96SB4 "SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK1 6732; "Homo sapiens (Human)" 0.957287 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 0.955426 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q14012 "Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1 8536; "Homo sapiens (Human)" 0.950981 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 0.94974 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8NG66 "Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK11 79858; "Homo sapiens (Human)" 0.941666 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9NR20 "Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK4 8798; "Homo sapiens (Human)" 0.939519 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O75460 "Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]" "Protein kinase superfamily, Ser/Thr protein kinase family" ERN1 2081; "Homo sapiens (Human)" 0.92831 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9UBF8 "Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) (NPIK) (PI4K92)" "PI3/PI4-kinase family, Type III PI4K subfamily" PI4KB 5298; "Homo sapiens (Human)" 0.926215 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 0.914482 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O60331 "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma)" PIP5K1C 23396; "Homo sapiens (Human)" 0.889716 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O95747 "Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" OXSR1 9943; "Homo sapiens (Human)" 0.884675 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O14578 "Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" CIT 11113; "Homo sapiens (Human)" 0.875764 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q99755 "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)" PIP5K1A 8394; "Homo sapiens (Human)" 0.849105 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 0.848574 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P51956 "Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (HSPK 36) (Never in mitosis A-related kinase 3) (NimA-related protein kinase 3)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK3 4752; "Homo sapiens (Human)" 0.844906 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q15831 "Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamily" STK11 6794; "Homo sapiens (Human)" 0.832822 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P53778 "Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK12 6300; "Homo sapiens (Human)" 0.831721 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P57078 "Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK4 "Homo sapiens (Human)" 0.801741 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q05655 "Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCD 5580; "Homo sapiens (Human)" 0.796804 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P52564 "Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6) (Stress-activated protein kinase kinase 3) (SAPK kinase 3) (SAPKK-3) (SAPKK3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K6 5608; "Homo sapiens (Human)" 0.775115 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P22694 "cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACB 5567; "Homo sapiens (Human)" 0.762331 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q92630 "Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK2 8445; "Homo sapiens (Human)" 0.742586 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9BVS4 "Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK2 55781; "Homo sapiens (Human)" 0.741797 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC P05129 "Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCG 5582; "Homo sapiens (Human)" 0.708354 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O15264 "Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK13 5603; "Homo sapiens (Human)" 0.668169 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q86UE8 "Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family" TLK2 11011; "Homo sapiens (Human)" 0.667705 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 0.66654 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8NI60 "Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (Coenzyme Q protein 8A) (aarF domain-containing protein kinase 3)" "Protein kinase superfamily, ADCK protein kinase family" COQ8A 56997; "Homo sapiens (Human)" 0.658287 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8NFD2 "Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" ANKK1 255239; "Homo sapiens (Human)" 0.638169 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q96NX5 "Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I gamma) (CaM kinase IG) (CaM-KI gamma) (CaMKI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1G 57172; "Homo sapiens (Human)" 0.635514 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q13153 "Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK1 5058; "Homo sapiens (Human)" 0.627159 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q8IY84 "Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" NIM1K 167359; "Homo sapiens (Human)" 0.578964 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 0.575 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9NQU5 "Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) (PAK-6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK6 106821730;56924; "Homo sapiens (Human)" 0.562666 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q15208 "Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" STK38 11329; "Homo sapiens (Human)" 0.51245 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 0.502645 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC Q9NRM7 "Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS2 26524; "Homo sapiens (Human)" 0.345227 Known 11 CHEMBL475251 COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC O00506 "Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK25 10494; "Homo sapiens (Human)" 0.215256 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O76039 "Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL5 6792; "Homo sapiens (Human)" 3.15964 1 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 3.06988 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P31645 "Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)" "Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamily" SLC6A4 6532; "Homo sapiens (Human)" 2.97375 2 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 2.9092 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P31749 "RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT1 207; "Homo sapiens (Human)" 2.88888 3 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 2.85421 4 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 2.68022 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 2.58505 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 2.47964 5 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 2.42003 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 2.41764 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q00537 "Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK17 5128; "Homo sapiens (Human)" 2.37176 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 2.33955 6 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O14936 "Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; MAGUK family" CASK 8573; "Homo sapiens (Human)" 2.33376 7 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9P0L2 "Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK1 4139; "Homo sapiens (Human)" 2.3264 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 2.32133 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13627 "Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1A 1859; "Homo sapiens (Human)" 2.31604 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P11309 "Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM1 5292; "Homo sapiens (Human)" 2.28432 8 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 2.27075 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q32MK0 "Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK3 91807; "Homo sapiens (Human)" 2.27056 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P45985 "Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K4 6416; "Homo sapiens (Human)" 2.24899 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O75914 "Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK3 5063; "Homo sapiens (Human)" 2.22806 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 2.21137 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q96L34 "MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK4 57787; "Homo sapiens (Human)" 2.1995 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q16816 "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG1 5260; "Homo sapiens (Human)" 2.19506 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 2.18162 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 2.17886 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 2.17336 9 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 2.16562 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 2.1541 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 2.14373 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13237 "cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG2 5593; "Homo sapiens (Human)" 2.14218 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9P286 "Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK5 57144; "Homo sapiens (Human)" 2.14015 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 2.13515 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 2.12985 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q15835 "Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK1 6011; "Homo sapiens (Human)" 2.12773 10 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 2.1179 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 2.11183 11 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 2.10964 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 2.10956 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q99755 "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)" PIP5K1A 8394; "Homo sapiens (Human)" 2.06741 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 2.06293 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 2.05293 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 2.02324 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P27448 "MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK3 4140; "Homo sapiens (Human)" 2.02168 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 2.01976 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 2.01551 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 2.01359 12 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 2.00725 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 1.99569 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 1.98568 13 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P78362 "SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK2 6733; "Homo sapiens (Human)" 1.98448 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 1.98322 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 1.97541 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 1.97315 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 1.96477 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 1.95129 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 1.9494 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 1.94302 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O94921 "Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK14 5218; "Homo sapiens (Human)" 1.93865 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 1.92898 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q04759 "Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCQ 5588; "Homo sapiens (Human)" 1.89862 14 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 1.89637 15 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q15139 "Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD1 5587; "Homo sapiens (Human)" 1.89581 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 1.89107 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13164 "Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK7 5598; "Homo sapiens (Human)" 1.88782 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UBE8 "Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" NLK 51701; "Homo sapiens (Human)" 1.88627 16 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q02779 "Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K10 4294; "Homo sapiens (Human)" 1.88355 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 1.87842 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9Y463 "Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1B 9149; "Homo sapiens (Human)" 1.87775 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9NWT8 "Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, mitochondrial) (MRP-S38) (Mitochondrial small ribosomal subunit protein mS38)" "Mitochondrion-specific ribosomal protein mS38 family" AURKAIP1 54998; "Homo sapiens (Human)" 1.87044 17 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 1.86985 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 1.86755 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9P2K8 "eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK4 440275; "Homo sapiens (Human)" 1.85189 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O15111 "Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" CHUK 1147; "Homo sapiens (Human)" 1.85038 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P24723 "Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCH 5583; "Homo sapiens (Human)" 1.84992 18 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9Y2K2 "Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK3 23387; "Homo sapiens (Human)" 1.8483 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 1.83676 19 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 1.83387 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 1.83238 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 1.83037 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q52WX2 "Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" SBK1 388228; "Homo sapiens (Human)" 1.82911 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 1.81323 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P54646 "5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA2 5563; "Homo sapiens (Human)" 1.80703 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9BXA7 "Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK1B 83942; "Homo sapiens (Human)" 1.80377 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UQ88 "Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 2) (Cell division protein kinase 11A) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK11A 728642; "Homo sapiens (Human)" 1.80135 20 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P0C264 "Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family member 3) (Sugen kinase 110)" "Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamily" SBK3 100130827; "Homo sapiens (Human)" 1.78396 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9Y243 "RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT3 10000; "Homo sapiens (Human)" 1.77569 21 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 1.77566 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q15759 "Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK11 5600; "Homo sapiens (Human)" 1.77521 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P52564 "Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6) (Stress-activated protein kinase kinase 3) (SAPK kinase 3) (SAPKK-3) (SAPKK3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K6 5608; "Homo sapiens (Human)" 1.77459 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 1.77439 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13554 "Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2B 816; "Homo sapiens (Human)" 1.75535 22 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.74771 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P78356 "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta)" PIP4K2B 8396; "Homo sapiens (Human)" 1.74464 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 1.74396 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 1.72711 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 1.7235 23 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.71832 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8TD08 "Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK15 225689; "Homo sapiens (Human)" 1.71271 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 1.71209 24 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 1.70973 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q6ZN16 "Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K15 389840; "Homo sapiens (Human)" 1.70539 25 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.69389 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 1.69388 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9C098 "Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK3 85443; "Homo sapiens (Human)" 1.68807 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P51817 "cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) (Protein kinase X-linked) (Serine/threonine-protein kinase PRKX) (EC 2.7.11.1) (Protein kinase PKX1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKX 5613; "Homo sapiens (Human)" 1.68794 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P42680 "Tyrosine-protein kinase Tec (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TEC 7006; "Homo sapiens (Human)" 1.68726 26 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 1.68228 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 1.66432 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 1.66207 27 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.65958 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13546 "Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK1 8737; "Homo sapiens (Human)" 1.65433 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 1.65178 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O00506 "Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK25 10494; "Homo sapiens (Human)" 1.64578 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 1.63386 28 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 1.63286 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 1.61666 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P21127 "Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK11B 984; "Homo sapiens (Human)" 1.61475 29 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O14578 "Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" CIT 11113; "Homo sapiens (Human)" 1.61265 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P22455 "Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR4 2264; "Homo sapiens (Human)" 1.605 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P22694 "cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACB 5567; "Homo sapiens (Human)" 1.59905 30 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 1.5985 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.59782 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9BRS2 "Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK1 83732; "Homo sapiens (Human)" 1.59429 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 1.5878 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9NQU5 "Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) (PAK-6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK6 106821730;56924; "Homo sapiens (Human)" 1.58488 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P17252 "Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCA 5578; "Homo sapiens (Human)" 1.58174 31 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 1.57965 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8IWQ3 "Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 2) (BR serine/threonine-protein kinase 2) (Serine/threonine-protein kinase 29) (Serine/threonine-protein kinase SAD-A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK2 9024; "Homo sapiens (Human)" 1.57891 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.5738 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P31751 "RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC-PK-beta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT2 208; "Homo sapiens (Human)" 1.57114 32 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 1.57058 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 1.56879 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 1.56869 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 1.56347 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O14730 "Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK3 8780; "Homo sapiens (Human)" 1.56314 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P57078 "Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK4 "Homo sapiens (Human)" 1.55536 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 1.55511 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 1.55366 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 1.54292 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.53293 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.52633 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q15831 "Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamily" STK11 6794; "Homo sapiens (Human)" 1.52134 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9Y2H9 "Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" MAST1 22983; "Homo sapiens (Human)" 1.51719 33 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UEE5 "Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17A 9263; "Homo sapiens (Human)" 1.51071 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8N5S9 "Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK1 84254; "Homo sapiens (Human)" 1.50231 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q02763 "Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TEK 7010; "Homo sapiens (Human)" 1.48951 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P0DMS8 "Adenosine receptor A3" "G-protein coupled receptor 1 family" ADORA3 140; "Homo sapiens (Human)" 1.48601 34 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 1.48465 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 1.48246 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O94768 "Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17B 9262; "Homo sapiens (Human)" 1.48051 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.46215 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 1.4591 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 1.45906 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P36897 "TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR1 7046; "Homo sapiens (Human)" 1.45879 35 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13523 "Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" PRPF4B 8899; "Homo sapiens (Human)" 1.45578 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9H1R3 "Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK2 85366; "Homo sapiens (Human)" 1.45238 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.44694 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P23975 "Sodium-dependent noradrenaline transporter (Norepinephrine transporter) (NET) (Solute carrier family 6 member 2)" "Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A2 subfamily" SLC6A2 6530; "Homo sapiens (Human)" 1.44139 36 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8NEV4 "Myosin-IIIa (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3A 53904; "Homo sapiens (Human)" 1.42668 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8NFD2 "Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" ANKK1 255239; "Homo sapiens (Human)" 1.42661 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q96Q40 "Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK15 65061; "Homo sapiens (Human)" 1.41951 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q07002 "Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK18 5129; "Homo sapiens (Human)" 1.41529 37 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.41509 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 1.41415 38 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 1.4046 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 1.39987 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q59H18 "Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" TNNI3K 100526835;51086; "Homo sapiens (Human)" 1.39808 39 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UQM7 "Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2A 815; "Homo sapiens (Human)" 1.39794 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 1.39455 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O00329 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)" "PI3/PI4-kinase family" PIK3CD 5293; "Homo sapiens (Human)" 1.37669 40 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 1.37612 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O15075 "Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK1 9201; "Homo sapiens (Human)" 1.37324 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P11511 "Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase)" "Cytochrome P450 family" CYP19A1 1588; "Homo sapiens (Human)" 1.37097 41 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q00526 "Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK3 1018; "Homo sapiens (Human)" 1.37036 42 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UEW8 "STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK39 27347; "Homo sapiens (Human)" 1.35908 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P14616 "Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSRR 3645; "Homo sapiens (Human)" 1.35639 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.35173 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q7KZI7 "Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK2 2011; "Homo sapiens (Human)" 1.35032 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.345 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 1.34418 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13555 "Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2G 818; "Homo sapiens (Human)" 1.34203 43 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 1.34018 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 1.33983 44 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 1.33766 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 1.33617 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 1.33077 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.32582 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 1.32489 45 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 1.32436 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 1.32422 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13153 "Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK1 5058; "Homo sapiens (Human)" 1.32184 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O15146 "Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)" "Protein kinase superfamily, Tyr protein kinase family" MUSK 4593; "Homo sapiens (Human)" 1.32184 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.3191 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.31648 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 1.31468 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 1.31452 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 1.3128 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 1.31052 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 1.30936 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 1.30857 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q16512 "Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN1 5585; "Homo sapiens (Human)" 1.29814 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 1.29634 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q15208 "Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" STK38 11329; "Homo sapiens (Human)" 1.28504 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.2835 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 1.27968 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 1.27372 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 1.27288 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8WTQ7 "Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK7 131890; "Homo sapiens (Human)" 1.27144 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P36896 "Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1B 91; "Homo sapiens (Human)" 1.26943 46 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9BQI3 "Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled repressor) (HCR) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Hemin-sensitive initiation factor 2-alpha kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK1 27102; "Homo sapiens (Human)" 1.26529 47 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P09874 "Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-)" PARP1 142; "Homo sapiens (Human)" 1.26213 48 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P42336 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)" "PI3/PI4-kinase family" PIK3CA 5290; "Homo sapiens (Human)" 1.25094 49 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q6XUX3 "Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)" "Protein kinase superfamily, Ser/Thr protein kinase family" DSTYK 25778; "Homo sapiens (Human)" 1.24746 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P57058 "Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase MAK-V)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" HUNK 30811; "Homo sapiens (Human)" 1.24714 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P43403 "Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" ZAP70 7535; "Homo sapiens (Human)" 1.24542 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 1.24341 50 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q86UE8 "Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family" TLK2 11011; "Homo sapiens (Human)" 1.23246 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 1.22349 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P49761 "Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK3 1198; "Homo sapiens (Human)" 1.21677 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.2064 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.20506 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13177 "Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK2 5062; "Homo sapiens (Human)" 1.19982 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8WU08 "Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32A 202374; "Homo sapiens (Human)" 1.19918 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 1.19829 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 1.19469 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9P289 "Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK26 51765; "Homo sapiens (Human)" 1.19462 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 1.1914 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.19014 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 1.18837 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9Y6E0 "Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK24 8428; "Homo sapiens (Human)" 1.18584 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 1.18571 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 1.18324 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 1.18027 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 1.17917 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 1.17607 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 1.16308 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q15375 "Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA7 2045; "Homo sapiens (Human)" 1.14888 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 1.14649 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P49674 "Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1E 102800317;1454; "Homo sapiens (Human)" 1.13773 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 1.13311 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O95747 "Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" OXSR1 9943; "Homo sapiens (Human)" 1.13213 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 1.12609 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P48729 "Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1 1452; "Homo sapiens (Human)" 1.12422 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9NRM7 "Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS2 26524; "Homo sapiens (Human)" 1.11466 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 1.11215 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 1.11138 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 1.10583 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8IW41 "MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAP-K5) (MAPKAPK-5) (MK-5) (MK5) (EC 2.7.11.1) (p38-regulated/activated protein kinase) (PRAK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MAPKAPK5 8550; "Homo sapiens (Human)" 1.10432 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P78368 "Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G2 1455; "Homo sapiens (Human)" 1.10334 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UKI8 "Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" TLK1 9874; "Homo sapiens (Human)" 1.09421 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 1.09393 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q09013 "Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) (DMPK) (Myotonic dystrophy protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" DMPK 1760; "Homo sapiens (Human)" 1.09341 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q96SB4 "SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK1 6732; "Homo sapiens (Human)" 1.091 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 1.08338 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q86YV6 "Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK4 340156; "Homo sapiens (Human)" 1.08029 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O43353 "Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK2 8767; "Homo sapiens (Human)" 1.07823 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 1.07807 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 1.07499 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 1.07259 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q92772 "Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL2 8999; "Homo sapiens (Human)" 1.07112 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.06467 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P41240 "Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" CSK 1445; "Homo sapiens (Human)" 1.0372 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q92630 "Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK2 8445; "Homo sapiens (Human)" 1.0362 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8WXR4 "Myosin-IIIb (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3B 140469; "Homo sapiens (Human)" 1.02939 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9UIK4 "Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK2 23604; "Homo sapiens (Human)" 1.02802 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 1.0214 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O75460 "Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]" "Protein kinase superfamily, Ser/Thr protein kinase family" ERN1 2081; "Homo sapiens (Human)" 1.00595 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9Y2H1 "Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" STK38L 23012; "Homo sapiens (Human)" 0.999675 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 0.997159 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P53355 "Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK1 1612; "Homo sapiens (Human)" 0.991355 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 0.989189 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P36894 "Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1A 657; "Homo sapiens (Human)" 0.985625 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P51957 "Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK4 6787; "Homo sapiens (Human)" 0.985394 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q00536 "Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK16 5127; "Homo sapiens (Human)" 0.981321 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 0.976978 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 0.975177 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O95835 "Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS1 9113; "Homo sapiens (Human)" 0.974007 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q96BR1 "Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK3 100533105;23678; "Homo sapiens (Human)" 0.97132 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 0.960653 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 0.959009 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13976 "cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG1 5592; "Homo sapiens (Human)" 0.941645 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 0.937618 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8TDC3 "Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK1 84446; "Homo sapiens (Human)" 0.910516 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 0.909218 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 0.908548 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q6DT37 "Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (MRCKG) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPG 55561; "Homo sapiens (Human)" 0.905433 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 0.901557 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9HC98 "Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6) (Protein kinase SID6-1512)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK6 10783; "Homo sapiens (Human)" 0.900312 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O96013 "Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK4 10298; "Homo sapiens (Human)" 0.880364 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 0.872335 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P30291 "Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE1 7465; "Homo sapiens (Human)" 0.870938 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P51955 "Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK2 4751; "Homo sapiens (Human)" 0.864448 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 0.852723 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 0.851879 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13705 "Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2B 93; "Homo sapiens (Human)" 0.834018 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8TD19 "Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK9 91754; "Homo sapiens (Human)" 0.823716 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9Y6R4 "Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K4 4216; "Homo sapiens (Human)" 0.82304 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8TDX7 "Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK7 140609; "Homo sapiens (Human)" 0.815323 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 0.807779 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q8IY84 "Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" NIM1K 167359; "Homo sapiens (Human)" 0.80255 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P42679 "Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" MATK 4145; "Homo sapiens (Human)" 0.785784 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q13873 "Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR2 659; "Homo sapiens (Human)" 0.775397 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 0.748313 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q96NX5 "Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I gamma) (CaM kinase IG) (CaM-KI gamma) (CaMKI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1G 57172; "Homo sapiens (Human)" 0.741688 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9HCP0 "Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G1 53944; "Homo sapiens (Human)" 0.732084 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q96PY6 "Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK1 4750; "Homo sapiens (Human)" 0.728878 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P51956 "Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (HSPK 36) (Never in mitosis A-related kinase 3) (NimA-related protein kinase 3)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK3 4752; "Homo sapiens (Human)" 0.683503 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 0.666522 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9BVS4 "Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK2 55781; "Homo sapiens (Human)" 0.643648 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 0.63686 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9Y6M4 "Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G3 1456; "Homo sapiens (Human)" 0.615445 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 0.586167 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 0.580319 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q9NYL2 "Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K20 51776; "Homo sapiens (Human)" 0.569536 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q6P3R8 "Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase 5) (NimA-related protein kinase 5)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK5 341676; "Homo sapiens (Human)" 0.558825 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P27037 "Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2A 92; "Homo sapiens (Human)" 0.500746 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q14012 "Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1 8536; "Homo sapiens (Human)" 0.442248 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 O14920 "Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKB 3551; "Homo sapiens (Human)" 0.421229 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 Q16659 "Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK6 5597; "Homo sapiens (Human)" 0.361921 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P19525 "Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK2 5610; "Homo sapiens (Human)" 0.306054 Known 13 CHEMBL1908397 O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 O=C(c1ccc(cc1)/C=C/c1n[nH]c2c1cccc2)N1CCNCC1 P0C1S8 "Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) (Wee1B kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE2 494551; "Homo sapiens (Human)" 0.295944 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 3.45278 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 3.3181 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 3.28398 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O43603 "Galanin receptor type 2 (GAL2-R) (GALR-2)" "G-protein coupled receptor 1 family" GALR2 8811; "Homo sapiens (Human)" 3.20898 1 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 3.05501 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 2.92918 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 2.89174 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 2.76989 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 2.71026 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 2.6426 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 2.61969 2 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 2.54677 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 2.53119 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 2.49079 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 2.45479 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 2.39444 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 2.38255 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 2.30545 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 2.2398 3 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 2.21219 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 2.21055 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 2.20928 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 2.18057 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 2.16715 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 2.16444 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 2.13923 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 2.11623 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 2.10795 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 2.07934 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 2.05724 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 2.01405 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 1.98712 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 1.97212 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.96141 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.94937 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 1.92361 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q00526 "Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK3 1018; "Homo sapiens (Human)" 1.9183 4 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P21860 "Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB3 2065; "Homo sapiens (Human)" 1.90987 5 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 1.90512 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 1.87735 6 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.86367 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P22455 "Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR4 2264; "Homo sapiens (Human)" 1.85949 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 1.84835 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 1.84206 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 1.81965 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 1.80704 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.80134 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.77811 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 1.77696 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 1.77679 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.76603 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 1.75188 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 1.74541 7 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P54646 "5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA2 5563; "Homo sapiens (Human)" 1.73079 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.72833 8 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 1.72779 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 1.71776 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 1.71158 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P42680 "Tyrosine-protein kinase Tec (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TEC 7006; "Homo sapiens (Human)" 1.71146 9 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q52WX2 "Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" SBK1 388228; "Homo sapiens (Human)" 1.711 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q92772 "Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL2 8999; "Homo sapiens (Human)" 1.68711 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 1.68534 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 1.68504 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 1.67758 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 1.66931 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 1.66444 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.66247 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9NWT8 "Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, mitochondrial) (MRP-S38) (Mitochondrial small ribosomal subunit protein mS38)" "Mitochondrion-specific ribosomal protein mS38 family" AURKAIP1 54998; "Homo sapiens (Human)" 1.64532 10 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 1.64515 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 1.633 11 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 1.6304 12 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 1.63037 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9UEE5 "Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17A 9263; "Homo sapiens (Human)" 1.62111 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 1.61924 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.61472 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P35372 "Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)" "G-protein coupled receptor 1 family" OPRM1 4988; "Homo sapiens (Human)" 1.60302 13 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 1.59666 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 1.58937 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 1.58232 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.58129 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 1.57909 14 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 1.56332 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 1.55212 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 1.54192 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 1.52269 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 1.52235 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 1.51554 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 1.5141 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.51219 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 1.51091 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 1.50954 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 1.50356 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 1.50321 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P24723 "Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCH 5583; "Homo sapiens (Human)" 1.50126 15 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q8TD08 "Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK15 225689; "Homo sapiens (Human)" 1.49798 16 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 1.49388 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q8WTQ7 "Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK7 131890; "Homo sapiens (Human)" 1.4916 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 1.48959 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 1.4856 17 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 1.48218 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 1.467 18 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 1.46254 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q8IWQ3 "Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 2) (BR serine/threonine-protein kinase 2) (Serine/threonine-protein kinase 29) (Serine/threonine-protein kinase SAD-A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK2 9024; "Homo sapiens (Human)" 1.4596 19 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q96L34 "MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK4 57787; "Homo sapiens (Human)" 1.45377 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 1.44679 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 1.44336 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P05771 "Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCB 5579; "Homo sapiens (Human)" 1.44319 20 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 1.43835 21 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 1.43463 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q00536 "Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK16 5127; "Homo sapiens (Human)" 1.43321 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.43289 22 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q6XUX3 "Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)" "Protein kinase superfamily, Ser/Thr protein kinase family" DSTYK 25778; "Homo sapiens (Human)" 1.42616 23 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q16816 "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG1 5260; "Homo sapiens (Human)" 1.42391 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.42229 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q86YV6 "Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK4 340156; "Homo sapiens (Human)" 1.40675 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 1.4016 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P53350 "Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK1 5347; "Homo sapiens (Human)" 1.4004 24 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.39612 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 1.39111 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9BRS2 "Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK1 83732; "Homo sapiens (Human)" 1.39009 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q13976 "cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG1 5592; "Homo sapiens (Human)" 1.38549 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 1.38183 25 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 1.38175 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q00537 "Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK17 5128; "Homo sapiens (Human)" 1.37562 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q32MK0 "Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK3 91807; "Homo sapiens (Human)" 1.37171 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.36786 26 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9BWU1 "Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK19 23097; "Homo sapiens (Human)" 1.36432 27 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q13627 "Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1A 1859; "Homo sapiens (Human)" 1.36035 28 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 1.3591 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P14616 "Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSRR 3645; "Homo sapiens (Human)" 1.35527 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P36896 "Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1B 91; "Homo sapiens (Human)" 1.3484 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 1.34382 29 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O75914 "Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK3 5063; "Homo sapiens (Human)" 1.34102 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q8TDC3 "Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK1 84446; "Homo sapiens (Human)" 1.325 30 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 1.31707 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P32239 "Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R)" "G-protein coupled receptor 1 family" CCKBR 887; "Homo sapiens (Human)" 1.31668 31 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 1.30522 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 1.28999 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q07002 "Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK18 5129; "Homo sapiens (Human)" 1.28838 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P11309 "Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM1 5292; "Homo sapiens (Human)" 1.28645 32 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 1.28271 33 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q13523 "Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" PRPF4B 8899; "Homo sapiens (Human)" 1.28254 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q99755 "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)" PIP5K1A 8394; "Homo sapiens (Human)" 1.27625 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P49674 "Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1E 102800317;1454; "Homo sapiens (Human)" 1.27246 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O15146 "Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)" "Protein kinase superfamily, Tyr protein kinase family" MUSK 4593; "Homo sapiens (Human)" 1.26866 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O15111 "Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" CHUK 1147; "Homo sapiens (Human)" 1.26728 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 1.26528 34 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9BVS4 "Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK2 55781; "Homo sapiens (Human)" 1.25949 35 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 1.25838 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.25623 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q13164 "Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK7 5598; "Homo sapiens (Human)" 1.25356 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 1.25232 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9P2K8 "eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK4 440275; "Homo sapiens (Human)" 1.25093 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q16566 "Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK4 814; "Homo sapiens (Human)" 1.24787 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9P289 "Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK26 51765; "Homo sapiens (Human)" 1.23582 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 1.23488 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.23436 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 1.23253 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q96BR1 "Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK3 100533105;23678; "Homo sapiens (Human)" 1.22928 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O14730 "Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK3 8780; "Homo sapiens (Human)" 1.22704 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 1.22659 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P78356 "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta)" PIP4K2B 8396; "Homo sapiens (Human)" 1.22654 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 1.22508 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.22295 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O14920 "Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKB 3551; "Homo sapiens (Human)" 1.21621 36 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 1.21484 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q15831 "Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamily" STK11 6794; "Homo sapiens (Human)" 1.21449 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 1.2101 37 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q04759 "Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCQ 5588; "Homo sapiens (Human)" 1.20526 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 1.20427 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 1.20329 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P28482 "Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK1 5594; "Homo sapiens (Human)" 1.19891 38 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9C098 "Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK3 85443; "Homo sapiens (Human)" 1.19319 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P49356 "Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta)" "Protein prenyltransferase subunit beta family" FNTB 100529261;2342; "Homo sapiens (Human)" 1.19257 39 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q96SB4 "SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK1 6732; "Homo sapiens (Human)" 1.18648 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q13237 "cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG2 5593; "Homo sapiens (Human)" 1.18346 40 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 1.17891 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 1.17498 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q8N568 "Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin domain-containing protein 3B) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK2 166614; "Homo sapiens (Human)" 1.17423 41 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 1.17181 42 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9Y2K2 "Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK3 23387; "Homo sapiens (Human)" 1.16714 43 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9UEW8 "STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK39 27347; "Homo sapiens (Human)" 1.167 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 1.16409 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 1.16224 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O94768 "Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17B 9262; "Homo sapiens (Human)" 1.15829 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P78362 "SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK2 6733; "Homo sapiens (Human)" 1.15589 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 1.13776 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.1268 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 1.12519 44 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P0C264 "Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family member 3) (Sugen kinase 110)" "Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamily" SBK3 100130827; "Homo sapiens (Human)" 1.12217 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P41240 "Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" CSK 1445; "Homo sapiens (Human)" 1.12056 45 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 1.11582 46 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 1.11513 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 1.115 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.11435 47 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 1.10719 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 1.10687 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 1.1044 48 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.10379 49 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 1.10295 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O15264 "Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK13 5603; "Homo sapiens (Human)" 1.10247 50 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 1.09634 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q13873 "Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR2 659; "Homo sapiens (Human)" 1.09425 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O96013 "Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK4 10298; "Homo sapiens (Human)" 1.08695 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.08568 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 1.07833 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.07543 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P36897 "TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR1 7046; "Homo sapiens (Human)" 1.07329 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O95747 "Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" OXSR1 9943; "Homo sapiens (Human)" 1.07247 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 1.07044 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P57078 "Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK4 "Homo sapiens (Human)" 1.06848 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q15835 "Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK1 6011; "Homo sapiens (Human)" 1.06644 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q13546 "Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK1 8737; "Homo sapiens (Human)" 1.06032 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9P0L2 "Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK1 4139; "Homo sapiens (Human)" 1.05913 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q8N5S9 "Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK1 84254; "Homo sapiens (Human)" 1.05344 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q16512 "Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN1 5585; "Homo sapiens (Human)" 1.04442 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9P286 "Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK5 57144; "Homo sapiens (Human)" 1.03983 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 1.02436 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 1.00534 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P37023 "Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVRL1 94; "Homo sapiens (Human)" 0.990479 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9NRM7 "Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS2 26524; "Homo sapiens (Human)" 0.98953 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 0.987108 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9Y6E0 "Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK24 8428; "Homo sapiens (Human)" 0.973796 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q15139 "Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD1 5587; "Homo sapiens (Human)" 0.97115 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 0.969342 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 0.951814 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 0.945944 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 0.941214 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 0.909249 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 0.909018 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q02779 "Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K10 4294; "Homo sapiens (Human)" 0.908528 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 0.897801 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 0.894459 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 0.887152 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 0.853743 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 0.845438 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O94921 "Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK14 5218; "Homo sapiens (Human)" 0.843609 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P27448 "MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK3 4140; "Homo sapiens (Human)" 0.835965 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q02763 "Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TEK 7010; "Homo sapiens (Human)" 0.821118 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 0.808682 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9H1R3 "Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK2 85366; "Homo sapiens (Human)" 0.806615 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 0.791541 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 0.776091 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P45985 "Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K4 6416; "Homo sapiens (Human)" 0.763805 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q13177 "Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK2 5062; "Homo sapiens (Human)" 0.760543 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 0.75336 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 0.704808 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q8WXR4 "Myosin-IIIb (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3B 140469; "Homo sapiens (Human)" 0.693245 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q6ZN16 "Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K15 389840; "Homo sapiens (Human)" 0.689726 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9UQM7 "Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2A 815; "Homo sapiens (Human)" 0.66837 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q14012 "Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1 8536; "Homo sapiens (Human)" 0.665354 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9UIK4 "Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK2 23604; "Homo sapiens (Human)" 0.663366 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9Y463 "Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1B 9149; "Homo sapiens (Human)" 0.657847 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 0.654645 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O95835 "Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS1 9113; "Homo sapiens (Human)" 0.640179 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q96NX5 "Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I gamma) (CaM kinase IG) (CaM-KI gamma) (CaMKI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1G 57172; "Homo sapiens (Human)" 0.638667 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 0.62999 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q7KZI7 "Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK2 2011; "Homo sapiens (Human)" 0.609971 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 0.609571 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O15075 "Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK1 9201; "Homo sapiens (Human)" 0.607888 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P43403 "Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" ZAP70 7535; "Homo sapiens (Human)" 0.598874 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" O75460 "Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]" "Protein kinase superfamily, Ser/Thr protein kinase family" ERN1 2081; "Homo sapiens (Human)" 0.596699 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9Y2H9 "Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" MAST1 22983; "Homo sapiens (Human)" 0.591593 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q9BXA7 "Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK1B 83942; "Homo sapiens (Human)" 0.546826 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 0.515797 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 0.460774 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 0.454426 Known 14 CHEMBL502835 "COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1" "COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc(cc1)N(C(=O)CN1CCN(CC1)C)C" P30291 "Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE1 7465; "Homo sapiens (Human)" 0.444548 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 3.40336 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 3.19141 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 3.16744 1 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 3.15569 2 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 2.94941 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 2.88223 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 2.76281 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.65912 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 2.56577 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P34913 "Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]" "AB hydrolase superfamily, Epoxide hydrolase family" EPHX2 2053; "Homo sapiens (Human)" 2.54379 3 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 2.52955 4 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 2.5274 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 2.51321 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 2.50627 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 2.46413 5 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q13546 "Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK1 8737; "Homo sapiens (Human)" 2.46187 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 2.40238 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 2.38947 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 2.37996 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q92772 "Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL2 8999; "Homo sapiens (Human)" 2.35017 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 2.24747 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 2.2405 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 2.22196 6 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 2.16567 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 2.14794 7 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 2.14525 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O14920 "Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKB 3551; "Homo sapiens (Human)" 2.12075 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 2.09959 8 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 2.09108 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 2.08976 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q02763 "Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TEK 7010; "Homo sapiens (Human)" 2.05686 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 2.04708 9 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 2.03528 10 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 2.03026 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q15759 "Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK11 5600; "Homo sapiens (Human)" 1.98799 11 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 1.98187 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q15375 "Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA7 2045; "Homo sapiens (Human)" 1.97681 12 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 1.97501 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 1.96893 13 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 1.96491 14 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q00526 "Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK3 1018; "Homo sapiens (Human)" 1.95673 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.93167 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 1.92228 15 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9BWU1 "Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK19 23097; "Homo sapiens (Human)" 1.91969 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 1.90993 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 1.89163 16 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.88366 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 1.86116 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 1.84037 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 1.83993 17 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 1.81502 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 1.81468 18 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 1.80527 19 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 1.78589 20 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P09960 "Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)" "Peptidase M1 family" LTA4H 4048; "Homo sapiens (Human)" 1.72907 21 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.71839 22 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 1.70995 23 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 1.7053 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 1.7034 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 1.69543 24 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P22455 "Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR4 2264; "Homo sapiens (Human)" 1.69376 25 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.68765 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 1.65788 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.64948 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 1.61171 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 1.59466 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q8IVW4 "Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine-protein kinase NKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL3 51265; "Homo sapiens (Human)" 1.59062 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 1.5893 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P04049 "RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" RAF1 5894; "Homo sapiens (Human)" 1.56926 26 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 1.56545 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 1.55385 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9NYL2 "Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K20 51776; "Homo sapiens (Human)" 1.53794 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P10275 "Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)" "Nuclear hormone receptor family, NR3 subfamily" AR 367; "Homo sapiens (Human)" 1.53651 27 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.5319 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.51691 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 1.50525 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 1.5026 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 1.49212 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 1.48014 28 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.47269 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 1.4644 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.46139 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.46086 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 1.45928 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 1.45504 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q00532 "Cyclin-dependent kinase-like 1 (EC 2.7.11.22) (Protein kinase p42 KKIALRE) (Serine/threonine-protein kinase KKIALRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL1 8814; "Homo sapiens (Human)" 1.45174 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 1.44185 29 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P20794 "Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" MAK 4117; "Homo sapiens (Human)" 1.43849 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 1.43464 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q07002 "Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK18 5129; "Homo sapiens (Human)" 1.43268 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.42816 30 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 1.42368 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O94921 "Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK14 5218; "Homo sapiens (Human)" 1.42278 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P57078 "Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK4 "Homo sapiens (Human)" 1.41215 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 1.39966 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 1.38821 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 1.38366 31 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 1.376 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O15264 "Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK13 5603; "Homo sapiens (Human)" 1.37533 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 1.37001 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 1.34876 32 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 1.3452 33 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 1.34471 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q00534 "Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK6 1021; "Homo sapiens (Human)" 1.3401 34 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 1.33542 35 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P53778 "Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK12 6300; "Homo sapiens (Human)" 1.32947 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.31506 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 1.30963 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9BVS4 "Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK2 55781; "Homo sapiens (Human)" 1.30833 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O14730 "Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK3 8780; "Homo sapiens (Human)" 1.30017 36 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.3 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q96Q40 "Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK15 65061; "Homo sapiens (Human)" 1.29342 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.2902 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.28783 37 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 1.28635 38 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 1.28588 39 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 1.28245 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 1.27739 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 1.27497 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 1.27445 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 1.26663 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P21860 "Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB3 2065; "Homo sapiens (Human)" 1.26275 40 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q00535 "Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK5 1020; "Homo sapiens (Human)" 1.25103 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 1.24985 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 1.23046 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9C098 "Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK3 85443; "Homo sapiens (Human)" 1.22547 41 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P21917 "D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)" "G-protein coupled receptor 1 family" DRD4 1815; "Homo sapiens (Human)" 1.22264 42 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9NWT8 "Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, mitochondrial) (MRP-S38) (Mitochondrial small ribosomal subunit protein mS38)" "Mitochondrion-specific ribosomal protein mS38 family" AURKAIP1 54998; "Homo sapiens (Human)" 1.22149 43 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 1.2196 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q32MK0 "Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK3 91807; "Homo sapiens (Human)" 1.21856 44 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P49674 "Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1E 102800317;1454; "Homo sapiens (Human)" 1.21297 45 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.21188 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.20546 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O15075 "Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK1 9201; "Homo sapiens (Human)" 1.20471 46 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9Y2K2 "Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK3 23387; "Homo sapiens (Human)" 1.18705 47 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 1.18557 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q8N568 "Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin domain-containing protein 3B) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK2 166614; "Homo sapiens (Human)" 1.18533 48 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 1.18459 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 1.17865 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 1.17507 49 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 1.15186 50 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O14733 "Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (Stress-activated protein kinase kinase 4) (SAPK kinase 4) (SAPKK-4) (SAPKK4) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K7 5609; "Homo sapiens (Human)" 1.1442 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 1.12149 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 1.11271 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 1.11029 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O76039 "Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL5 6792; "Homo sapiens (Human)" 1.10571 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P29323 "Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB2 2048; "Homo sapiens (Human)" 1.10547 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 1.10234 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 1.09963 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.09934 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 1.08887 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.07439 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 1.06934 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 1.06011 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P14616 "Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSRR 3645; "Homo sapiens (Human)" 1.05781 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q8TD08 "Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK15 225689; "Homo sapiens (Human)" 1.0563 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P42679 "Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" MATK 4145; "Homo sapiens (Human)" 1.03727 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O15111 "Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" CHUK 1147; "Homo sapiens (Human)" 1.01102 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 1.00854 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P51957 "Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK4 6787; "Homo sapiens (Human)" 0.992683 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q6XUX3 "Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)" "Protein kinase superfamily, Ser/Thr protein kinase family" DSTYK 25778; "Homo sapiens (Human)" 0.986288 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P51817 "cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) (Protein kinase X-linked) (Serine/threonine-protein kinase PRKX) (EC 2.7.11.1) (Protein kinase PKX1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKX 5613; "Homo sapiens (Human)" 0.979403 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9HC98 "Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6) (Protein kinase SID6-1512)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK6 10783; "Homo sapiens (Human)" 0.965983 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q00537 "Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK17 5128; "Homo sapiens (Human)" 0.964763 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 0.960942 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O15146 "Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)" "Protein kinase superfamily, Tyr protein kinase family" MUSK 4593; "Homo sapiens (Human)" 0.959127 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 0.926821 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 0.923705 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 0.905505 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q96BR1 "Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK3 100533105;23678; "Homo sapiens (Human)" 0.878948 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P54756 "Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA5 2044; "Homo sapiens (Human)" 0.876885 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q13233 "Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K1 4214; "Homo sapiens (Human)" 0.871196 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 0.866251 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 0.859835 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 0.855189 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 0.844441 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q8TD19 "Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK9 91754; "Homo sapiens (Human)" 0.835471 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 0.829907 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q92630 "Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK2 8445; "Homo sapiens (Human)" 0.823851 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 0.821052 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 0.820469 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9UEW8 "STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK39 27347; "Homo sapiens (Human)" 0.810207 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 0.8 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P49761 "Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK3 1198; "Homo sapiens (Human)" 0.795959 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 0.795002 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O14578 "Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" CIT 11113; "Homo sapiens (Human)" 0.788899 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q8NEV4 "Myosin-IIIa (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3A 53904; "Homo sapiens (Human)" 0.764992 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 0.75557 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9Y6E0 "Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK24 8428; "Homo sapiens (Human)" 0.754109 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 0.749935 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 0.710259 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 0.705611 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 0.677611 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 0.665292 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9UBE8 "Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" NLK 51701; "Homo sapiens (Human)" 0.66409 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 0.656335 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O75914 "Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK3 5063; "Homo sapiens (Human)" 0.648973 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9H4B4 "Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3) (Proliferation-related kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK3 1263; "Homo sapiens (Human)" 0.631865 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9HCP0 "Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G1 53944; "Homo sapiens (Human)" 0.625 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P37173 "TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR2 7048; "Homo sapiens (Human)" 0.620324 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 0.601386 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q96PY6 "Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK1 4750; "Homo sapiens (Human)" 0.584491 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 0.583469 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P45985 "Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K4 6416; "Homo sapiens (Human)" 0.57423 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 0.56997 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 0.569877 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 0.563198 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P22694 "cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACB 5567; "Homo sapiens (Human)" 0.498633 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q59H18 "Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" TNNI3K 100526835;51086; "Homo sapiens (Human)" 0.484645 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P53671 "LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK2 3985; "Homo sapiens (Human)" 0.483127 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q8N5S9 "Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK1 84254; "Homo sapiens (Human)" 0.479111 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9Y2H1 "Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" STK38L 23012; "Homo sapiens (Human)" 0.427634 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9NRM7 "Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS2 26524; "Homo sapiens (Human)" 0.408456 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q13705 "Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2B 93; "Homo sapiens (Human)" 0.407696 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 0.394708 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9BUB5 "MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK1 8569; "Homo sapiens (Human)" 0.377247 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q8WXR4 "Myosin-IIIb (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3B 140469; "Homo sapiens (Human)" 0.362486 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O95382 "Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K6 9064; "Homo sapiens (Human)" 0.351698 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 0.31053 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC O75460 "Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]" "Protein kinase superfamily, Ser/Thr protein kinase family" ERN1 2081; "Homo sapiens (Human)" 0.305138 Known 15 CHEMBL574738 CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)Nc1ccc(cc1)Oc1ncnc(c1)NC Q9Y6M4 "Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G3 1456; "Homo sapiens (Human)" 0.301425 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 3.65154 1 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 2.96199 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 2.73158 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 2.68245 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P21860 "Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB3 2065; "Homo sapiens (Human)" 2.53132 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 2.45443 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 2.42829 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 2.42109 2 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 2.37398 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 2.36538 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 2.32454 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 2.31886 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 2.3142 3 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 2.30487 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 2.2778 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 2.2284 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 2.21906 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 2.21757 4 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 2.21552 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 2.20939 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 2.2075 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 2.20463 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 2.20006 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 2.17253 5 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 2.15852 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 2.15182 6 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 2.12755 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 2.09176 7 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 2.07958 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 2.05536 8 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 2.05508 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 2.03346 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 1.997 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 1.99007 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 1.98416 9 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 1.98396 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.9756 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P54764 "Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA4 2043; "Homo sapiens (Human)" 1.96837 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 1.95955 10 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 1.94238 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 1.93872 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 1.91565 11 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q04759 "Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCQ 5588; "Homo sapiens (Human)" 1.9117 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 1.91001 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q13164 "Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK7 5598; "Homo sapiens (Human)" 1.89836 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.89663 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q13639 "5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4)" "G-protein coupled receptor 1 family" HTR4 3360; "Homo sapiens (Human)" 1.89131 12 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q00535 "Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK5 1020; "Homo sapiens (Human)" 1.88028 13 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P0C1S8 "Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) (Wee1B kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE2 494551; "Homo sapiens (Human)" 1.87266 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.87239 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 1.86469 14 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.84569 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.84192 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P27448 "MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK3 4140; "Homo sapiens (Human)" 1.83841 15 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.83602 16 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 1.83115 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q00526 "Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK3 1018; "Homo sapiens (Human)" 1.82577 17 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 1.80622 18 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9P289 "Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK26 51765; "Homo sapiens (Human)" 1.80045 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 1.78118 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 1.7649 19 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 1.76475 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 1.75535 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q15375 "Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA7 2045; "Homo sapiens (Human)" 1.74429 20 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 1.72882 21 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 1.7159 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 1.70981 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P04049 "RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" RAF1 5894; "Homo sapiens (Human)" 1.7079 22 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 1.70024 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P29323 "Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB2 2048; "Homo sapiens (Human)" 1.69595 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 1.68376 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O43353 "Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK2 8767; "Homo sapiens (Human)" 1.67878 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 1.67352 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.66527 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8N5S9 "Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK1 84254; "Homo sapiens (Human)" 1.66177 23 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 1.65952 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 1.65297 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.6388 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8TD08 "Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK15 225689; "Homo sapiens (Human)" 1.63853 24 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 1.63644 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9C098 "Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK3 85443; "Homo sapiens (Human)" 1.63628 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 1.6302 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9NYL2 "Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K20 51776; "Homo sapiens (Human)" 1.61367 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.60888 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 1.60663 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 1.60131 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 1.59795 25 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 1.59711 26 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 1.58969 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 1.58054 27 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.57471 28 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 1.56615 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.55 29 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P14616 "Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSRR 3645; "Homo sapiens (Human)" 1.54765 30 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 1.54198 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9P2K8 "eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK4 440275; "Homo sapiens (Human)" 1.52064 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 1.5191 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P17252 "Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCA 5578; "Homo sapiens (Human)" 1.51298 31 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P54756 "Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA5 2044; "Homo sapiens (Human)" 1.51248 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 1.51058 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P41279 "Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (Cancer Osaka thyroid oncogene) (Proto-oncogene c-Cot) (Serine/threonine-protein kinase cot) (Tumor progression locus 2) (TPL-2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K8 1326; "Homo sapiens (Human)" 1.50026 32 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P05771 "Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCB 5579; "Homo sapiens (Human)" 1.49934 33 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.49209 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 1.48834 34 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P54753 "Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) (EPH-like kinase 2) (Embryonic kinase 2) (EK2) (hEK2) (Tyrosine-protein kinase TYRO6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB3 2049; "Homo sapiens (Human)" 1.48453 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 1.4825 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9NYY3 "Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) (Serine/threonine-protein kinase SNK) (hSNK) (Serum-inducible kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK2 10769; "Homo sapiens (Human)" 1.48169 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O94921 "Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK14 5218; "Homo sapiens (Human)" 1.47544 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 1.47401 35 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.45469 36 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 1.44246 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 1.43877 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 1.42823 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q00537 "Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK17 5128; "Homo sapiens (Human)" 1.42708 37 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 1.41981 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 1.41637 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P20794 "Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" MAK 4117; "Homo sapiens (Human)" 1.41035 38 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q96D53 "Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase 4) (Coenzyme Q protein 8B)" "Protein kinase superfamily, ADCK protein kinase family" COQ8B 79934; "Homo sapiens (Human)" 1.40268 39 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 1.3979 40 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q15759 "Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK11 5600; "Homo sapiens (Human)" 1.39639 41 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9UIK4 "Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK2 23604; "Homo sapiens (Human)" 1.39625 42 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 1.38624 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 1.37236 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.37211 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q96L34 "MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK4 57787; "Homo sapiens (Human)" 1.36875 43 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P24723 "Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCH 5583; "Homo sapiens (Human)" 1.35746 44 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q13557 "Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2D 817; "Homo sapiens (Human)" 1.35574 45 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.35563 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 1.35419 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9BWU1 "Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK19 23097; "Homo sapiens (Human)" 1.34383 46 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 1.34336 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 1.34316 47 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O15146 "Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)" "Protein kinase superfamily, Tyr protein kinase family" MUSK 4593; "Homo sapiens (Human)" 1.34232 48 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 1.3391 49 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9Y6R4 "Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K4 4216; "Homo sapiens (Human)" 1.33756 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O14920 "Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKB 3551; "Homo sapiens (Human)" 1.33346 50 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q16816 "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG1 5260; "Homo sapiens (Human)" 1.31822 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 1.30519 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 1.29918 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 1.29593 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 1.29113 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q6XUX3 "Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)" "Protein kinase superfamily, Ser/Thr protein kinase family" DSTYK 25778; "Homo sapiens (Human)" 1.28765 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 1.28755 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q13555 "Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2G 818; "Homo sapiens (Human)" 1.27782 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q59H18 "Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" TNNI3K 100526835;51086; "Homo sapiens (Human)" 1.27483 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9Y6E0 "Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK24 8428; "Homo sapiens (Human)" 1.27089 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 1.2681 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 1.26436 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 1.25926 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P42680 "Tyrosine-protein kinase Tec (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TEC 7006; "Homo sapiens (Human)" 1.24252 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P41240 "Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" CSK 1445; "Homo sapiens (Human)" 1.23896 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.22301 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 1.21983 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 1.20525 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 1.20176 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 1.18226 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P53350 "Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK1 5347; "Homo sapiens (Human)" 1.18139 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q05655 "Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCD 5580; "Homo sapiens (Human)" 1.16271 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9Y2K2 "Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK3 23387; "Homo sapiens (Human)" 1.16093 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 1.1595 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 1.15838 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 1.15558 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 1.15376 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9BXA7 "Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK1B 83942; "Homo sapiens (Human)" 1.13446 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O14936 "Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; MAGUK family" CASK 8573; "Homo sapiens (Human)" 1.13085 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.12571 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P49674 "Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1E 102800317;1454; "Homo sapiens (Human)" 1.12147 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P43403 "Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" ZAP70 7535; "Homo sapiens (Human)" 1.12046 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P49761 "Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK3 1198; "Homo sapiens (Human)" 1.11177 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 1.1019 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 1.0967 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O75914 "Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK3 5063; "Homo sapiens (Human)" 1.08252 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O00506 "Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK25 10494; "Homo sapiens (Human)" 1.08105 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 1.07072 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 1.07037 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 1.07024 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 1.06791 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 1.06704 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 1.06563 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 1.03528 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 1.0207 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 1.01966 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 1.01903 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 1.01666 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 1.01017 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q96Q40 "Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK15 65061; "Homo sapiens (Human)" 1.0085 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9UQM7 "Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2A 815; "Homo sapiens (Human)" 0.988931 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 0.979464 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P48729 "Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1 1452; "Homo sapiens (Human)" 0.979227 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 0.97429 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P51955 "Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK2 4751; "Homo sapiens (Human)" 0.973556 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8WTQ7 "Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK7 131890; "Homo sapiens (Human)" 0.967215 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8WU08 "Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32A 202374; "Homo sapiens (Human)" 0.960685 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 0.952627 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 0.948712 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9Y2H9 "Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" MAST1 22983; "Homo sapiens (Human)" 0.946678 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 0.92244 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q99640 "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" PKMYT1 9088; "Homo sapiens (Human)" 0.921408 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 0.91262 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O14730 "Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK3 8780; "Homo sapiens (Human)" 0.91233 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 0.906148 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q09013 "Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) (DMPK) (Myotonic dystrophy protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" DMPK 1760; "Homo sapiens (Human)" 0.900698 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9UBE8 "Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" NLK 51701; "Homo sapiens (Human)" 0.899195 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9UKI8 "Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" TLK1 9874; "Homo sapiens (Human)" 0.892764 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9NRP7 "Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK36 27148; "Homo sapiens (Human)" 0.877177 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P45985 "Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K4 6416; "Homo sapiens (Human)" 0.863565 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8WXR4 "Myosin-IIIb (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3B 140469; "Homo sapiens (Human)" 0.859716 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8NG66 "Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK11 79858; "Homo sapiens (Human)" 0.854458 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9BRS2 "Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK1 83732; "Homo sapiens (Human)" 0.847719 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9UEW8 "STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK39 27347; "Homo sapiens (Human)" 0.824101 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O14733 "Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (Stress-activated protein kinase kinase 4) (SAPK kinase 4) (SAPKK-4) (SAPKK4) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K7 5609; "Homo sapiens (Human)" 0.822809 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q13177 "Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK2 5062; "Homo sapiens (Human)" 0.820509 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q99755 "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)" PIP5K1A 8394; "Homo sapiens (Human)" 0.817625 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q13153 "Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK1 5058; "Homo sapiens (Human)" 0.806173 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 0.805865 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q16512 "Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN1 5585; "Homo sapiens (Human)" 0.802364 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 0.801438 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 0.796794 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 0.791793 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 0.788729 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9BQI3 "Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled repressor) (HCR) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Hemin-sensitive initiation factor 2-alpha kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK1 27102; "Homo sapiens (Human)" 0.7439 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q86Y07 "Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, VRK subfamily" VRK2 7444; "Homo sapiens (Human)" 0.74243 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P30291 "Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE1 7465; "Homo sapiens (Human)" 0.735538 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q00536 "Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK16 5127; "Homo sapiens (Human)" 0.732115 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 0.721936 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 0.720235 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 0.711399 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 0.703784 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 0.699252 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 0.667991 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8IY84 "Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" NIM1K 167359; "Homo sapiens (Human)" 0.667475 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P52564 "Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6) (Stress-activated protein kinase kinase 3) (SAPK kinase 3) (SAPKK-3) (SAPKK3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K6 5608; "Homo sapiens (Human)" 0.657849 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q02156 "Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCE 5581; "Homo sapiens (Human)" 0.649175 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8NEV4 "Myosin-IIIa (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3A 53904; "Homo sapiens (Human)" 0.628516 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q13873 "Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR2 659; "Homo sapiens (Human)" 0.601408 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q86UE8 "Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family" TLK2 11011; "Homo sapiens (Human)" 0.563085 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 0.560579 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 0.495492 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q02763 "Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TEK 7010; "Homo sapiens (Human)" 0.478278 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8NFD2 "Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" ANKK1 255239; "Homo sapiens (Human)" 0.473774 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q13233 "Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K1 4214; "Homo sapiens (Human)" 0.469052 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 0.464326 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P42679 "Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" MATK 4145; "Homo sapiens (Human)" 0.428052 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N O14578 "Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" CIT 11113; "Homo sapiens (Human)" 0.41522 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q8N752 "Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1L 122011; "Homo sapiens (Human)" 0.386598 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 0.312623 Known 16 CHEMBL288441 COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N P57058 "Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase MAK-V)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" HUNK 30811; "Homo sapiens (Human)" 0.287418 Known 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P48067 "Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9)" "Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A9 subfamily" SLC6A9 6536; "Homo sapiens (Human)" 3.32467 1 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 3.31986 2 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 3.29963 3 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 3.26275 4 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 3.0196 5 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 2.4938 6 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 2.44834 7 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 2.40903 8 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 2.30779 9 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P09874 "Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-)" PARP1 142; "Homo sapiens (Human)" 2.25052 10 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 2.15467 11 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P35270 "Sepiapterin reductase (SPR) (EC 1.1.1.153)" "Sepiapterin reductase family" SPR 6697; "Homo sapiens (Human)" 2.14797 12 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.05055 13 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P49286 "Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)" "G-protein coupled receptor 1 family" MTNR1B 4544; "Homo sapiens (Human)" 1.95781 14 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" O14744 "Protein arginine N-methyltransferase 5 (EC 2.1.1.320) (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed]" "Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family" PRMT5 10419; "Homo sapiens (Human)" 1.85702 15 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P21917 "D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)" "G-protein coupled receptor 1 family" DRD4 1815; "Homo sapiens (Human)" 1.8193 16 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P03372 "Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)" "Nuclear hormone receptor family, NR3 subfamily" ESR1 2099; "Homo sapiens (Human)" 1.74394 17 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P48039 "Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)" "G-protein coupled receptor 1 family" MTNR1A 4543; "Homo sapiens (Human)" 1.72857 18 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P08908 "5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)" "G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamily" HTR1A 3350; "Homo sapiens (Human)" 1.70338 19 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 1.7007 20 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" Q9HCG7 "Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (Beta-glucocerebrosidase 2) (Beta-glucosidase 2) (Bile acid beta-glucosidase GBA2) (Bile acid glucosyl transferase GBA2) (Cholesterol glucosyltransferase GBA2) (EC 2.4.1.-) (Cholesteryl-beta-glucosidase GBA2) (EC 3.2.1.104) (Glucosylceramidase 2)" "Non-lysosomal glucosylceramidase family" GBA2 57704; "Homo sapiens (Human)" 1.68972 21 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.67347 22 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" O43570 "Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)" "Alpha-carbonic anhydrase family" CA12 771; "Homo sapiens (Human)" 1.64895 23 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P35367 "Histamine H1 receptor (H1R) (HH1R)" "G-protein coupled receptor 1 family" HRH1 3269; "Homo sapiens (Human)" 1.63123 24 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" Q13639 "5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4)" "G-protein coupled receptor 1 family" HTR4 3360; "Homo sapiens (Human)" 1.57076 25 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P00918 "Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)" "Alpha-carbonic anhydrase family" CA2 760; "Homo sapiens (Human)" 1.56019 26 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P78527 "DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)" "PI3/PI4-kinase family" PRKDC 5591; "Homo sapiens (Human)" 1.55877 27 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 1.52191 28 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" Q13547 "Histone deacetylase 1 (HD1) (EC 3.5.1.98)" "Histone deacetylase family, HD type 1 subfamily" HDAC1 3065; "Homo sapiens (Human)" 1.51373 29 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P34913 "Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]" "AB hydrolase superfamily, Epoxide hydrolase family" EPHX2 2053; "Homo sapiens (Human)" 1.50389 30 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P09960 "Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)" "Peptidase M1 family" LTA4H 4048; "Homo sapiens (Human)" 1.47564 31 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P41595 "5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)" "G-protein coupled receptor 1 family" HTR2B 3357; "Homo sapiens (Human)" 1.4749 32 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 1.44663 33 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" Q99720 "Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding protein) (SR-BP) (Sigma 1-type opioid receptor) (SIG-1R) (Sigma1-receptor) (Sigma1R) (hSigmaR1)" "ERG2 family" SIGMAR1 10280; "Homo sapiens (Human)" 1.43602 34 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" Q92731 "Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)" "Nuclear hormone receptor family, NR3 subfamily" ESR2 2100; "Homo sapiens (Human)" 1.37351 35 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" Q99705 "Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein coupled receptor 24) (MCH-1R) (MCH1R) (MCHR) (SLC-1) (Somatostatin receptor-like protein)" "G-protein coupled receptor 1 family" MCHR1 2847; "Homo sapiens (Human)" 1.35599 36 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P34969 "5-hydroxytryptamine receptor 7 (5-HT-7) (5-HT7) (5-HT-X) (Serotonin receptor 7)" "G-protein coupled receptor 1 family" HTR7 3363; "Homo sapiens (Human)" 1.3533 37 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" O15379 "Histone deacetylase 3 (HD3) (EC 3.5.1.98) (RPD3-2) (SMAP45)" "Histone deacetylase family, HD type 1 subfamily" HDAC3 8841; "Homo sapiens (Human)" 1.35327 38 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 1.35261 39 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P31645 "Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)" "Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamily" SLC6A4 6532; "Homo sapiens (Human)" 1.34954 40 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P00915 "Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase B) (CAB) (Carbonic anhydrase I) (CA-I)" "Alpha-carbonic anhydrase family" CA1 759; "Homo sapiens (Human)" 1.31734 41 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P35348 "Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1A sub-subfamily" ADRA1A 148; "Homo sapiens (Human)" 1.31548 42 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" Q8NER1 "Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)" "Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamily" TRPV1 7442; "Homo sapiens (Human)" 1.30318 43 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P00742 "Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]" "Peptidase S1 family" F10 2159; "Homo sapiens (Human)" 1.27956 44 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P41146 "Nociceptin receptor (Kappa-type 3 opioid receptor) (KOR-3) (Orphanin FQ receptor)" "G-protein coupled receptor 1 family" OPRL1 4987; "Homo sapiens (Human)" 1.26431 45 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P50406 "5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)" "G-protein coupled receptor 1 family" HTR6 3362; "Homo sapiens (Human)" 1.24706 46 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" Q16790 "Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)" "Alpha-carbonic anhydrase family" CA9 768; "Homo sapiens (Human)" 1.2411 47 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 1.23084 48 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P11511 "Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase)" "Cytochrome P450 family" CYP19A1 1588; "Homo sapiens (Human)" 1.22646 49 18 CHEMBL1721885 "Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1" "O[C@H](CN1CCOCC1)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2" P27338 "Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B)" "Flavin monoamine oxidase family" MAOB 4129; "Homo sapiens (Human)" 1.21311 50 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 3.24354 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 3.16341 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 3.14845 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 3.02944 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 2.97173 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 2.91122 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 2.88619 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 2.86287 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 2.79437 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 2.76616 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 2.75587 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 2.71679 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 2.66322 1 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 2.63216 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 2.57806 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 2.56824 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 2.55166 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 2.54748 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 2.52476 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 2.52363 2 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 2.52205 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 2.50597 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 2.49694 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 2.4737 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 2.45283 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 2.40505 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 2.40245 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 2.34405 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 2.33537 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 2.32413 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 2.30172 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 2.29921 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 2.29476 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 2.29451 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P30291 "Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE1 7465; "Homo sapiens (Human)" 2.27457 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 2.26365 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.2195 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P42680 "Tyrosine-protein kinase Tec (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TEC 7006; "Homo sapiens (Human)" 2.20686 3 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 2.18074 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 2.14582 4 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 2.14197 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 2.06648 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 2.0514 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 2.04113 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9NYY3 "Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) (Serine/threonine-protein kinase SNK) (hSNK) (Serum-inducible kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK2 10769; "Homo sapiens (Human)" 2.02516 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 2.00472 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 2.00002 5 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.99948 6 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 1.99321 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P27448 "MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK3 4140; "Homo sapiens (Human)" 1.98071 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 1.97835 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 1.97475 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P48736 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)" "PI3/PI4-kinase family" PIK3CG 5294; "Homo sapiens (Human)" 1.96216 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q00526 "Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK3 1018; "Homo sapiens (Human)" 1.96131 7 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.95337 8 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.92388 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 1.92229 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 1.90938 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q96L34 "MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK4 57787; "Homo sapiens (Human)" 1.90851 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 1.89509 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.88604 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9C098 "Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK3 85443; "Homo sapiens (Human)" 1.87485 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q00535 "Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK5 1020; "Homo sapiens (Human)" 1.86931 9 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P14616 "Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSRR 3645; "Homo sapiens (Human)" 1.85156 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q96D53 "Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase 4) (Coenzyme Q protein 8B)" "Protein kinase superfamily, ADCK protein kinase family" COQ8B 79934; "Homo sapiens (Human)" 1.84035 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 1.83044 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 1.83019 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P17252 "Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCA 5578; "Homo sapiens (Human)" 1.82159 10 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 1.81195 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 1.80832 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 1.80688 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 1.80393 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 1.79217 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 1.78849 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P21860 "Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB3 2065; "Homo sapiens (Human)" 1.78417 11 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 1.77928 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 1.77502 12 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.775 13 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P34913 "Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]" "AB hydrolase superfamily, Epoxide hydrolase family" EPHX2 2053; "Homo sapiens (Human)" 1.7704 14 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9NWT8 "Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, mitochondrial) (MRP-S38) (Mitochondrial small ribosomal subunit protein mS38)" "Mitochondrion-specific ribosomal protein mS38 family" AURKAIP1 54998; "Homo sapiens (Human)" 1.76726 15 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q52WX2 "Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" SBK1 388228; "Homo sapiens (Human)" 1.76587 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 1.7553 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 1.75312 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 1.74999 16 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P37023 "Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVRL1 94; "Homo sapiens (Human)" 1.74979 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 1.74462 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 1.74405 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O14920 "Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKB 3551; "Homo sapiens (Human)" 1.74282 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8N5S9 "Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK1 84254; "Homo sapiens (Human)" 1.74074 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 1.73346 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 1.73005 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 1.72996 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O94921 "Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK14 5218; "Homo sapiens (Human)" 1.72654 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.72191 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 1.70853 17 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 1.70609 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9BXA7 "Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK1B 83942; "Homo sapiens (Human)" 1.70609 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 1.70229 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P42336 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)" "PI3/PI4-kinase family" PIK3CA 5290; "Homo sapiens (Human)" 1.70122 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9P2K8 "eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK4 440275; "Homo sapiens (Human)" 1.69916 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 1.6981 18 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13164 "Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK7 5598; "Homo sapiens (Human)" 1.69614 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13557 "Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2D 817; "Homo sapiens (Human)" 1.68724 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 1.66992 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q16816 "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG1 5260; "Homo sapiens (Human)" 1.66954 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O75914 "Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK3 5063; "Homo sapiens (Human)" 1.66518 19 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 1.65 20 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.65 21 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.64652 22 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8N568 "Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin domain-containing protein 3B) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK2 166614; "Homo sapiens (Human)" 1.64549 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P78362 "SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK2 6733; "Homo sapiens (Human)" 1.64245 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 1.63558 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.62869 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 1.614 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 1.59677 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.59651 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 1.58769 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 1.58699 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 1.58433 23 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 1.575 24 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.57471 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.57439 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9P286 "Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK5 57144; "Homo sapiens (Human)" 1.5677 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8TD19 "Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK9 91754; "Homo sapiens (Human)" 1.56385 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 1.56067 25 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q15759 "Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK11 5600; "Homo sapiens (Human)" 1.55595 26 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 1.55495 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 1.55443 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.54853 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 1.54794 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13555 "Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2G 818; "Homo sapiens (Human)" 1.5471 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.54576 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P0C1S8 "Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) (Wee1B kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE2 494551; "Homo sapiens (Human)" 1.53122 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q05655 "Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCD 5580; "Homo sapiens (Human)" 1.525 27 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 1.52499 28 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 1.5249 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 1.52476 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 1.52065 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O43570 "Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)" "Alpha-carbonic anhydrase family" CA12 771; "Homo sapiens (Human)" 1.50857 29 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P53355 "Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK1 1612; "Homo sapiens (Human)" 1.50396 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8TDC3 "Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK1 84446; "Homo sapiens (Human)" 1.5 30 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P42338 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta)" "PI3/PI4-kinase family" PIK3CB 5291; "Homo sapiens (Human)" 1.49879 31 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O00329 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)" "PI3/PI4-kinase family" PIK3CD 5293; "Homo sapiens (Human)" 1.49415 32 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P22455 "Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR4 2264; "Homo sapiens (Human)" 1.49352 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q15375 "Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA7 2045; "Homo sapiens (Human)" 1.48814 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.48305 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P00918 "Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)" "Alpha-carbonic anhydrase family" CA2 760; "Homo sapiens (Human)" 1.48135 33 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 1.47696 34 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.46945 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 1.46887 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P36894 "Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1A 657; "Homo sapiens (Human)" 1.4568 35 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 1.45553 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9BWU1 "Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK19 23097; "Homo sapiens (Human)" 1.45437 36 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.45312 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q00534 "Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK6 1021; "Homo sapiens (Human)" 1.45302 37 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9Y2K2 "Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK3 23387; "Homo sapiens (Human)" 1.44498 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 1.44471 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P53350 "Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK1 5347; "Homo sapiens (Human)" 1.44005 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8TD08 "Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK15 225689; "Homo sapiens (Human)" 1.43317 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P24723 "Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCH 5583; "Homo sapiens (Human)" 1.43171 38 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 1.43097 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 1.42465 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 1.42288 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 1.42082 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P09960 "Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)" "Peptidase M1 family" LTA4H 4048; "Homo sapiens (Human)" 1.42068 39 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O15146 "Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)" "Protein kinase superfamily, Tyr protein kinase family" MUSK 4593; "Homo sapiens (Human)" 1.42049 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O94768 "Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17B 9262; "Homo sapiens (Human)" 1.4171 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 1.41664 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 1.41367 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13705 "Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2B 93; "Homo sapiens (Human)" 1.40535 40 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 1.40493 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 1.4014 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9UIK4 "Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK2 23604; "Homo sapiens (Human)" 1.39705 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.39625 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O15111 "Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" CHUK 1147; "Homo sapiens (Human)" 1.39442 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 1.39129 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 1.3884 41 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q07002 "Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK18 5129; "Homo sapiens (Human)" 1.38686 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 1.38503 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9P0L2 "Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK1 4139; "Homo sapiens (Human)" 1.38299 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q16790 "Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)" "Alpha-carbonic anhydrase family" CA9 768; "Homo sapiens (Human)" 1.37657 42 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P0C264 "Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family member 3) (Sugen kinase 110)" "Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamily" SBK3 100130827; "Homo sapiens (Human)" 1.37127 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8TDX7 "Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK7 140609; "Homo sapiens (Human)" 1.36147 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 1.35959 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 1.35672 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9H4B4 "Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3) (Proliferation-related kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK3 1263; "Homo sapiens (Human)" 1.34846 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 1.34471 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 1.34144 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 1.33632 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 1.32839 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 1.32217 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q59H18 "Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" TNNI3K 100526835;51086; "Homo sapiens (Human)" 1.32006 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q86YV6 "Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK4 340156; "Homo sapiens (Human)" 1.31835 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q7KZI7 "Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK2 2011; "Homo sapiens (Human)" 1.3163 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13237 "cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG2 5593; "Homo sapiens (Human)" 1.31484 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q15139 "Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD1 5587; "Homo sapiens (Human)" 1.3087 43 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.30809 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 1.30637 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 1.30357 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 1.29798 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q15831 "Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamily" STK11 6794; "Homo sapiens (Human)" 1.29654 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 1.29578 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 1.29444 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8IVW4 "Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine-protein kinase NKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL3 51265; "Homo sapiens (Human)" 1.29348 44 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P36896 "Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1B 91; "Homo sapiens (Human)" 1.29087 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.28063 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 1.27014 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P37173 "TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR2 7048; "Homo sapiens (Human)" 1.26773 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P20794 "Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" MAK 4117; "Homo sapiens (Human)" 1.26317 45 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q15569 "Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" TESK1 7016; "Homo sapiens (Human)" 1.2556 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.25233 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P04049 "RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" RAF1 5894; "Homo sapiens (Human)" 1.24915 46 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9HC98 "Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6) (Protein kinase SID6-1512)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK6 10783; "Homo sapiens (Human)" 1.23999 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P78356 "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta)" PIP4K2B 8396; "Homo sapiens (Human)" 1.23111 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 1.22118 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.21994 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O14936 "Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; MAGUK family" CASK 8573; "Homo sapiens (Human)" 1.21261 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 1.20989 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P27986 "Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)" "PI3K p85 subunit family" PIK3R1 5295; "Homo sapiens (Human)" 1.20704 47 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P03372 "Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)" "Nuclear hormone receptor family, NR3 subfamily" ESR1 2099; "Homo sapiens (Human)" 1.19814 48 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P19525 "Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK2 5610; "Homo sapiens (Human)" 1.18489 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9P289 "Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK26 51765; "Homo sapiens (Human)" 1.18148 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P54646 "5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA2 5563; "Homo sapiens (Human)" 1.17087 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 1.17052 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q96Q40 "Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK15 65061; "Homo sapiens (Human)" 1.17046 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P34969 "5-hydroxytryptamine receptor 7 (5-HT-7) (5-HT7) (5-HT-X) (Serotonin receptor 7)" "G-protein coupled receptor 1 family" HTR7 3363; "Homo sapiens (Human)" 1.16992 49 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.16344 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P51957 "Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK4 6787; "Homo sapiens (Human)" 1.16231 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 1.15337 50 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q6P3R8 "Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase 5) (NimA-related protein kinase 5)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK5 341676; "Homo sapiens (Human)" 1.15299 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P29323 "Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB2 2048; "Homo sapiens (Human)" 1.14735 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P45985 "Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K4 6416; "Homo sapiens (Human)" 1.14205 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O15075 "Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK1 9201; "Homo sapiens (Human)" 1.1376 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8TBX8 "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma)" PIP4K2C 79837; "Homo sapiens (Human)" 1.13423 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O14730 "Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK3 8780; "Homo sapiens (Human)" 1.1328 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 1.1266 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q96SB4 "SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK1 6732; "Homo sapiens (Human)" 1.12397 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 1.11838 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9UKI8 "Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" TLK1 9874; "Homo sapiens (Human)" 1.09965 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8WTQ7 "Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK7 131890; "Homo sapiens (Human)" 1.09173 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q02779 "Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K10 4294; "Homo sapiens (Human)" 1.07994 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13873 "Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR2 659; "Homo sapiens (Human)" 1.07847 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 1.07621 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q96BR1 "Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK3 100533105;23678; "Homo sapiens (Human)" 1.06996 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q02763 "Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TEK 7010; "Homo sapiens (Human)" 1.057 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9BRS2 "Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK1 83732; "Homo sapiens (Human)" 1.05045 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 1.04713 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q16512 "Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN1 5585; "Homo sapiens (Human)" 1.0363 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 1.02893 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9UQM7 "Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2A 815; "Homo sapiens (Human)" 1.02723 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 1.02716 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q00537 "Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK17 5128; "Homo sapiens (Human)" 1.01663 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 1.01638 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13177 "Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK2 5062; "Homo sapiens (Human)" 1.00733 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 1.00365 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 0.999745 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 0.992493 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9UBF8 "Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) (NPIK) (PI4K92)" "PI3/PI4-kinase family, Type III PI4K subfamily" PI4KB 5298; "Homo sapiens (Human)" 0.981678 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13976 "cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG1 5592; "Homo sapiens (Human)" 0.980054 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O60885 "Bromodomain-containing protein 4 (Protein HUNK1)" BRD4 23476; "Homo sapiens (Human)" 0.968412 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 0.966785 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 0.962663 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 0.955289 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q14012 "Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1 8536; "Homo sapiens (Human)" 0.950981 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9NRP7 "Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK36 27148; "Homo sapiens (Human)" 0.949187 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 0.946504 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q32MK0 "Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK3 91807; "Homo sapiens (Human)" 0.944299 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8NG66 "Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK11 79858; "Homo sapiens (Human)" 0.931832 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O75460 "Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]" "Protein kinase superfamily, Ser/Thr protein kinase family" ERN1 2081; "Homo sapiens (Human)" 0.92831 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 0.927237 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 0.92424 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 0.923675 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P54764 "Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA4 2043; "Homo sapiens (Human)" 0.917936 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P42679 "Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" MATK 4145; "Homo sapiens (Human)" 0.917721 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q6XUX3 "Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)" "Protein kinase superfamily, Ser/Thr protein kinase family" DSTYK 25778; "Homo sapiens (Human)" 0.893508 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9UEW8 "STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK39 27347; "Homo sapiens (Human)" 0.886875 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P41240 "Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" CSK 1445; "Homo sapiens (Human)" 0.884826 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q00536 "Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK16 5127; "Homo sapiens (Human)" 0.884247 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O96013 "Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK4 10298; "Homo sapiens (Human)" 0.880054 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O14578 "Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" CIT 11113; "Homo sapiens (Human)" 0.875764 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9NRH2 "SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" SNRK 54861; "Homo sapiens (Human)" 0.872794 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q58F21 "Bromodomain testis-specific protein (Cancer/testis antigen 9) (CT9) (RING3-like protein)" BRDT 676; "Homo sapiens (Human)" 0.871806 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P51956 "Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (HSPK 36) (Never in mitosis A-related kinase 3) (NimA-related protein kinase 3)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK3 4752; "Homo sapiens (Human)" 0.869616 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 0.865642 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q99755 "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)" PIP5K1A 8394; "Homo sapiens (Human)" 0.849105 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 0.848537 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P53671 "LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK2 3985; "Homo sapiens (Human)" 0.830948 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9Y463 "Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1B 9149; "Homo sapiens (Human)" 0.830569 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9NYL2 "Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K20 51776; "Homo sapiens (Human)" 0.821773 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9BQI3 "Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled repressor) (HCR) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Hemin-sensitive initiation factor 2-alpha kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK1 27102; "Homo sapiens (Human)" 0.810549 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8IY84 "Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" NIM1K 167359; "Homo sapiens (Human)" 0.808886 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9BUB5 "MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK1 8569; "Homo sapiens (Human)" 0.804479 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 0.80341 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O00506 "Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK25 10494; "Homo sapiens (Human)" 0.803302 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P51955 "Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK2 4751; "Homo sapiens (Human)" 0.79213 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9UEE5 "Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17A 9263; "Homo sapiens (Human)" 0.778667 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 0.777282 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9H1R3 "Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK2 85366; "Homo sapiens (Human)" 0.753356 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 0.743531 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9BVS4 "Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK2 55781; "Homo sapiens (Human)" 0.741797 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P43403 "Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" ZAP70 7535; "Homo sapiens (Human)" 0.735069 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9Y6R4 "Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K4 4216; "Homo sapiens (Human)" 0.706455 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13523 "Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" PRPF4B 8899; "Homo sapiens (Human)" 0.683061 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 0.67383 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q86UE8 "Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family" TLK2 11011; "Homo sapiens (Human)" 0.673306 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q92772 "Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL2 8999; "Homo sapiens (Human)" 0.643407 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8NFD2 "Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" ANKK1 255239; "Homo sapiens (Human)" 0.638169 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q96NX5 "Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I gamma) (CaM kinase IG) (CaM-KI gamma) (CaMKI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1G 57172; "Homo sapiens (Human)" 0.635514 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13153 "Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK1 5058; "Homo sapiens (Human)" 0.627159 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q16659 "Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK6 5597; "Homo sapiens (Human)" 0.623191 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P57078 "Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK4 "Homo sapiens (Human)" 0.617752 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q8NI60 "Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (Coenzyme Q protein 8A) (aarF domain-containing protein kinase 3)" "Protein kinase superfamily, ADCK protein kinase family" COQ8A 56997; "Homo sapiens (Human)" 0.610042 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q96PY6 "Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK1 4750; "Homo sapiens (Human)" 0.596074 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q09013 "Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) (DMPK) (Myotonic dystrophy protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" DMPK 1760; "Homo sapiens (Human)" 0.592571 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9NQU5 "Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) (PAK-6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK6 106821730;56924; "Homo sapiens (Human)" 0.562665 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q15208 "Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" STK38 11329; "Homo sapiens (Human)" 0.527028 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 0.51251 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 0.489857 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13546 "Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK1 8737; "Homo sapiens (Human)" 0.466823 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q13554 "Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2B 816; "Homo sapiens (Human)" 0.46106 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O43353 "Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK2 8767; "Homo sapiens (Human)" 0.459597 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 0.434688 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q02156 "Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCE 5581; "Homo sapiens (Human)" 0.425676 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 O76039 "Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL5 6792; "Homo sapiens (Human)" 0.414024 Known 19 CHEMBL1287853 Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 Cc1cnc(nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C)Nc1ccc(cc1)OCCN1CCCC1 Q9NRM7 "Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS2 26524; "Homo sapiens (Human)" 0.345227 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 3.5165 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 3.43844 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 3.38344 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 3.37304 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 3.32 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 3.26216 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q7KZI7 "Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK2 2011; "Homo sapiens (Human)" 3.25782 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 3.18643 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 3.16842 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 3.10935 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 3.08997 1 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q16816 "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG1 5260; "Homo sapiens (Human)" 3.06709 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q8N5S9 "Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK1 84254; "Homo sapiens (Human)" 3.01427 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 2.96332 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 2.94966 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 2.92658 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 2.90872 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 2.90192 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 2.89594 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9UQM7 "Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2A 815; "Homo sapiens (Human)" 2.87371 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9UEE5 "Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17A 9263; "Homo sapiens (Human)" 2.86836 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q16512 "Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN1 5585; "Homo sapiens (Human)" 2.85747 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.85146 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13557 "Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2D 817; "Homo sapiens (Human)" 2.85145 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 2.80656 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P27448 "MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK3 4140; "Homo sapiens (Human)" 2.80263 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q8WTQ7 "Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK7 131890; "Homo sapiens (Human)" 2.75889 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P05771 "Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCB 5579; "Homo sapiens (Human)" 2.7488 2 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 2.71002 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 2.69143 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 2.68047 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 2.66018 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 2.65618 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O94768 "Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17B 9262; "Homo sapiens (Human)" 2.64477 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 2.64039 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 2.63679 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 2.61286 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 2.60884 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9P0L2 "Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK1 4139; "Homo sapiens (Human)" 2.57926 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 2.57773 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 2.5735 3 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 2.55245 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13627 "Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1A 1859; "Homo sapiens (Human)" 2.52423 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 2.52098 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9P2K8 "eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK4 440275; "Homo sapiens (Human)" 2.51838 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 2.50937 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 2.50386 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 2.48777 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 2.48529 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 2.47622 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 2.47244 4 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 2.46864 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q15835 "Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK1 6011; "Homo sapiens (Human)" 2.45013 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 2.44654 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 2.44181 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 2.43408 5 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 2.42646 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 2.42542 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9BRS2 "Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK1 83732; "Homo sapiens (Human)" 2.42014 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 2.4163 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q15139 "Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD1 5587; "Homo sapiens (Human)" 2.41317 6 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9NRM7 "Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS2 26524; "Homo sapiens (Human)" 2.40524 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 2.39298 7 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q96SB4 "SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK1 6732; "Homo sapiens (Human)" 2.3893 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 2.38662 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 2.36302 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q02156 "Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCE 5581; "Homo sapiens (Human)" 2.36032 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 2.35666 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 2.35522 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 2.35374 8 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 2.34579 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 2.33508 9 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 2.33158 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 2.32238 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 2.32213 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 2.31428 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 2.3087 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 2.3034 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 2.30224 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 2.29497 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O75914 "Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK3 5063; "Homo sapiens (Human)" 2.29376 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q99755 "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)" PIP5K1A 8394; "Homo sapiens (Human)" 2.27782 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 2.27761 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 2.26894 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q02779 "Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K10 4294; "Homo sapiens (Human)" 2.26427 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 2.25314 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 2.25263 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 2.25054 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P45985 "Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K4 6416; "Homo sapiens (Human)" 2.24899 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 2.24876 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 2.24733 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 2.24452 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P78356 "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta)" PIP4K2B 8396; "Homo sapiens (Human)" 2.23844 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 2.23744 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 2.22869 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 2.2267 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9NQU5 "Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) (PAK-6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK6 106821730;56924; "Homo sapiens (Human)" 2.21963 10 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q8IWQ3 "Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 2) (BR serine/threonine-protein kinase 2) (Serine/threonine-protein kinase 29) (Serine/threonine-protein kinase SAD-A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK2 9024; "Homo sapiens (Human)" 2.21493 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9Y2K2 "Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK3 23387; "Homo sapiens (Human)" 2.2008 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 2.19929 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9P286 "Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK5 57144; "Homo sapiens (Human)" 2.1989 11 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O96013 "Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK4 10298; "Homo sapiens (Human)" 2.19811 12 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 2.19638 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q32MK0 "Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK3 91807; "Homo sapiens (Human)" 2.19487 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 2.19129 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P24723 "Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCH 5583; "Homo sapiens (Human)" 2.18328 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P53355 "Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK1 1612; "Homo sapiens (Human)" 2.18059 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q04759 "Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCQ 5588; "Homo sapiens (Human)" 2.17721 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q05655 "Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCD 5580; "Homo sapiens (Human)" 2.16692 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P11309 "Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM1 5292; "Homo sapiens (Human)" 2.16639 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 2.1607 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 2.15883 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 2.15852 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 2.14791 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 2.14374 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 2.13659 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 2.1351 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13153 "Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK1 5058; "Homo sapiens (Human)" 2.13093 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 2.13077 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13555 "Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2G 818; "Homo sapiens (Human)" 2.11357 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O15111 "Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" CHUK 1147; "Homo sapiens (Human)" 2.11182 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q96L34 "MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK4 57787; "Homo sapiens (Human)" 2.10984 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q96BR1 "Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK3 100533105;23678; "Homo sapiens (Human)" 2.10321 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 2.10221 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 2.10174 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 2.09112 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 2.08995 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P05129 "Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCG 5582; "Homo sapiens (Human)" 2.08907 13 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 2.0878 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13554 "Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2B 816; "Homo sapiens (Human)" 2.07785 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O14730 "Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK3 8780; "Homo sapiens (Human)" 2.07414 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 2.07413 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 2.07302 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 2.07039 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P54646 "5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA2 5563; "Homo sapiens (Human)" 2.05884 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 2.04232 14 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9Y463 "Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1B 9149; "Homo sapiens (Human)" 2.0247 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13237 "cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG2 5593; "Homo sapiens (Human)" 2.00934 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 2.0009 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9UIK4 "Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK2 23604; "Homo sapiens (Human)" 1.99892 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 1.9923 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 1.98348 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 1.97888 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 1.96068 15 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q8TDC3 "Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK1 84446; "Homo sapiens (Human)" 1.95729 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q86YV6 "Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK4 340156; "Homo sapiens (Human)" 1.95722 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 1.95597 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 1.95538 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 1.94284 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P43403 "Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" ZAP70 7535; "Homo sapiens (Human)" 1.94108 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q6XUX3 "Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)" "Protein kinase superfamily, Ser/Thr protein kinase family" DSTYK 25778; "Homo sapiens (Human)" 1.93567 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 1.93558 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 1.92775 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.92743 16 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.92658 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P51817 "cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) (Protein kinase X-linked) (Serine/threonine-protein kinase PRKX) (EC 2.7.11.1) (Protein kinase PKX1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKX 5613; "Homo sapiens (Human)" 1.92534 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 1.919 17 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q92630 "Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK2 8445; "Homo sapiens (Human)" 1.91714 18 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 1.91523 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13177 "Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK2 5062; "Homo sapiens (Human)" 1.91435 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 1.91024 19 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P17252 "Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCA 5578; "Homo sapiens (Human)" 1.90972 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9C098 "Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK3 85443; "Homo sapiens (Human)" 1.90484 20 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 1.90435 21 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.89105 22 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q02763 "Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TEK 7010; "Homo sapiens (Human)" 1.88641 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q14012 "Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1 8536; "Homo sapiens (Human)" 1.87117 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P78362 "SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK2 6733; "Homo sapiens (Human)" 1.85161 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q09013 "Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) (DMPK) (Myotonic dystrophy protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" DMPK 1760; "Homo sapiens (Human)" 1.84553 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 1.82385 23 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 1.80551 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 1.79829 24 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 1.7973 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P80370 "Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen 1 (FA1)]" DLK1 8788; "Homo sapiens (Human)" 1.79343 25 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 1.78877 26 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 1.77375 27 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 1.76623 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 1.76344 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 1.76169 28 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 1.75885 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O75460 "Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]" "Protein kinase superfamily, Ser/Thr protein kinase family" ERN1 2081; "Homo sapiens (Human)" 1.75403 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 1.75366 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13546 "Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK1 8737; "Homo sapiens (Human)" 1.74563 29 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 1.73295 30 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 1.72452 31 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 1.72343 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.72288 32 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 1.7176 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 1.70017 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 1.69854 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O95835 "Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS1 9113; "Homo sapiens (Human)" 1.69229 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.68283 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 1.68009 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P57078 "Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK4 "Homo sapiens (Human)" 1.67483 33 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P22694 "cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACB 5567; "Homo sapiens (Human)" 1.6727 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 1.66072 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13976 "cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG1 5592; "Homo sapiens (Human)" 1.65769 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q00536 "Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK16 5127; "Homo sapiens (Human)" 1.65036 34 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.64735 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9BXA7 "Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK1B 83942; "Homo sapiens (Human)" 1.6464 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P31749 "RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT1 207; "Homo sapiens (Human)" 1.64556 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.62663 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q5VT25 "Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPA 8476; "Homo sapiens (Human)" 1.62199 35 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 1.6197 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9NYY3 "Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) (Serine/threonine-protein kinase SNK) (hSNK) (Serum-inducible kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK2 10769; "Homo sapiens (Human)" 1.61557 36 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O00506 "Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK25 10494; "Homo sapiens (Human)" 1.61002 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 1.59113 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O00750 "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta)" "PI3/PI4-kinase family" PIK3C2B 5287; "Homo sapiens (Human)" 1.57969 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.57046 37 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q96NX5 "Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I gamma) (CaM kinase IG) (CaM-KI gamma) (CaMKI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1G 57172; "Homo sapiens (Human)" 1.55185 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.55171 38 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q52WX2 "Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" SBK1 388228; "Homo sapiens (Human)" 1.54986 39 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q8TD08 "Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK15 225689; "Homo sapiens (Human)" 1.54767 40 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 1.54544 41 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q8NFD2 "Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" ANKK1 255239; "Homo sapiens (Human)" 1.54433 42 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q15831 "Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamily" STK11 6794; "Homo sapiens (Human)" 1.54082 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q00535 "Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK5 1020; "Homo sapiens (Human)" 1.53565 43 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 1.53281 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O76039 "Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL5 6792; "Homo sapiens (Human)" 1.52388 44 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 1.52031 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.51643 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 1.50458 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9BWU1 "Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK19 23097; "Homo sapiens (Human)" 1.50428 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9Y2H9 "Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" MAST1 22983; "Homo sapiens (Human)" 1.50159 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 1.49569 45 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q13523 "Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" PRPF4B 8899; "Homo sapiens (Human)" 1.49319 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P52564 "Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6) (Stress-activated protein kinase kinase 3) (SAPK kinase 3) (SAPKK-3) (SAPKK3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K6 5608; "Homo sapiens (Human)" 1.48702 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 1.48482 46 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 1.4759 47 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9H1R3 "Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK2 85366; "Homo sapiens (Human)" 1.46467 48 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 1.46452 49 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 1.453 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.44692 50 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 1.4128 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O14920 "Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKB 3551; "Homo sapiens (Human)" 1.41196 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P30291 "Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE1 7465; "Homo sapiens (Human)" 1.39385 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 1.37889 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P19525 "Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK2 5610; "Homo sapiens (Human)" 1.36734 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P57058 "Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase MAK-V)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" HUNK 30811; "Homo sapiens (Human)" 1.35219 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 1.34856 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.31378 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.25004 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O43172 "U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4)" PRPF4 9128; "Homo sapiens (Human)" 1.24486 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 1.194 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P41240 "Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" CSK 1445; "Homo sapiens (Human)" 1.19381 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P31751 "RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC-PK-beta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT2 208; "Homo sapiens (Human)" 1.17568 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9H2K2 "Poly [ADP-ribose] polymerase tankyrase-2 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (Poly [ADP-ribose] polymerase 5B) (Protein poly-ADP-ribosyltransferase tankyrase-2) (EC 2.4.2.-) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II) (Tankyrase-2) (TANK2) (Tankyrase-like protein) (Tankyrase-related protein)" TNKS2 80351; "Homo sapiens (Human)" 1.12549 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P42336 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)" "PI3/PI4-kinase family" PIK3CA 5290; "Homo sapiens (Human)" 1.04634 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C O75747 "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma (PI3K-C2-gamma) (PtdIns-3-kinase C2 subunit gamma) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-gamma)" "PI3/PI4-kinase family" PIK3C2G 5288; "Homo sapiens (Human)" 1.03262 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9BVS4 "Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK2 55781; "Homo sapiens (Human)" 0.974281 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q9Y243 "RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT3 10000; "Homo sapiens (Human)" 0.958426 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C Q8WU08 "Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32A 202374; "Homo sapiens (Human)" 0.931027 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P49761 "Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK3 1198; "Homo sapiens (Human)" 0.834806 Known 20 CHEMBL608533 CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 0.798916 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 3.39795 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 2.95001 1 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 2.93635 2 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 2.897 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 2.85178 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 2.71584 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 2.65009 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 2.60792 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 2.60751 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 2.59608 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.54761 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 2.49713 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 2.49446 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 2.45468 3 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q13557 "Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2D 817; "Homo sapiens (Human)" 2.41759 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 2.35002 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 2.32108 4 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 2.30105 5 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 2.29036 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 2.27911 6 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 2.27629 7 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 2.27152 8 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 2.26803 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 2.25071 9 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P30291 "Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE1 7465; "Homo sapiens (Human)" 2.23189 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 2.19252 10 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 2.19138 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 2.18402 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 2.17176 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 2.17166 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 2.15002 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 2.12747 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 2.07563 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 2.07037 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 2.06674 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 2.06243 11 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q32MK0 "Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK3 91807; "Homo sapiens (Human)" 2.05016 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 2.0406 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 1.97473 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 1.95715 12 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 1.94163 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.93698 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 1.93644 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 1.92987 13 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 1.91944 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 1.91489 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.87614 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 1.87023 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 1.86844 14 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 1.85516 15 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 1.85001 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 1.85 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 1.84448 16 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 1.83957 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 1.8343 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 1.83188 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q05655 "Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCD 5580; "Homo sapiens (Human)" 1.8288 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 1.82776 17 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 1.8243 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 1.82371 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q92772 "Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL2 8999; "Homo sapiens (Human)" 1.82129 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 1.81561 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 1.80873 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.80439 18 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 1.80323 19 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.8 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 1.79987 20 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 1.79247 21 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 1.79019 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.77499 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 1.76129 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q96L34 "MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK4 57787; "Homo sapiens (Human)" 1.7473 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.72749 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 1.7258 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 1.72257 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P27448 "MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK3 4140; "Homo sapiens (Human)" 1.70769 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 1.69999 22 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 1.68049 23 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9P2K8 "eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK4 440275; "Homo sapiens (Human)" 1.67858 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P0C1S8 "Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) (Wee1B kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE2 494551; "Homo sapiens (Human)" 1.67439 24 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q13555 "Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2G 818; "Homo sapiens (Human)" 1.67125 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 1.66913 25 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 1.66357 26 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.65097 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 1.65 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 1.64212 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 1.63693 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 1.63618 27 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 1.61348 28 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9Y243 "RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT3 10000; "Homo sapiens (Human)" 1.61086 29 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 1.60001 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 1.57635 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 1.5648 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 1.5558 30 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.55232 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q04759 "Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCQ 5588; "Homo sapiens (Human)" 1.54939 31 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 1.53578 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9Y463 "Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1B 9149; "Homo sapiens (Human)" 1.53435 32 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.53261 33 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 1.52112 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9NYL2 "Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K20 51776; "Homo sapiens (Human)" 1.50494 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P14616 "Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSRR 3645; "Homo sapiens (Human)" 1.49566 34 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 1.49535 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q00535 "Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK5 1020; "Homo sapiens (Human)" 1.48157 35 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P24723 "Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCH 5583; "Homo sapiens (Human)" 1.46807 36 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 1.4655 37 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 1.46346 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 1.46091 38 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P05771 "Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCB 5579; "Homo sapiens (Human)" 1.4507 39 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P05129 "Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCG 5582; "Homo sapiens (Human)" 1.43861 40 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 1.4384 41 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P21917 "D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)" "G-protein coupled receptor 1 family" DRD4 1815; "Homo sapiens (Human)" 1.43676 42 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 1.425 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 1.42184 43 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 1.41668 44 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 1.41659 45 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 1.41465 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.41349 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 1.40674 46 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.39999 47 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.39818 48 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.39584 49 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.39535 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 1.39192 50 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 1.38524 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9BVS4 "Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK2 55781; "Homo sapiens (Human)" 1.37203 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9BXA7 "Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK1B 83942; "Homo sapiens (Human)" 1.3663 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 1.36486 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 1.36393 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 1.35736 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.35 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 1.33251 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 1.32511 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q7KZI7 "Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK2 2011; "Homo sapiens (Human)" 1.31523 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 1.29711 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 1.28297 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 1.25666 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.25598 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q52WX2 "Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" SBK1 388228; "Homo sapiens (Human)" 1.24844 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 1.24681 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 1.225 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.22164 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 1.20107 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 1.20088 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 1.20021 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 1.2 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.2 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q8TDC3 "Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK1 84446; "Homo sapiens (Human)" 1.2 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 1.19828 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 1.18515 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.16887 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 1.15 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P51957 "Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK4 6787; "Homo sapiens (Human)" 1.1 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 1.08795 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q15835 "Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK1 6011; "Homo sapiens (Human)" 1.0782 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9HBY8 "Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK2 10110; "Homo sapiens (Human)" 1.075 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P51955 "Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK2 4751; "Homo sapiens (Human)" 1.07397 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 1.06658 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9Y2H9 "Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" MAST1 22983; "Homo sapiens (Human)" 1.0564 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 1.04423 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 1.0421 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P78362 "SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK2 6733; "Homo sapiens (Human)" 1.02744 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q8WTQ7 "Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK7 131890; "Homo sapiens (Human)" 1.02702 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 1.00157 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 0.998282 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O96013 "Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK4 10298; "Homo sapiens (Human)" 0.975 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 0.942061 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 0.939562 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9UEW8 "STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK39 27347; "Homo sapiens (Human)" 0.93876 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 0.930318 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 0.92609 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P51817 "cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) (Protein kinase X-linked) (Serine/threonine-protein kinase PRKX) (EC 2.7.11.1) (Protein kinase PKX1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKX 5613; "Homo sapiens (Human)" 0.912451 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 0.875 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P57058 "Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase MAK-V)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" HUNK 30811; "Homo sapiens (Human)" 0.874083 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q96SB4 "SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK1 6732; "Homo sapiens (Human)" 0.871547 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 0.862953 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 0.856512 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9NYY3 "Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) (Serine/threonine-protein kinase SNK) (hSNK) (Serum-inducible kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK2 10769; "Homo sapiens (Human)" 0.851423 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q15208 "Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" STK38 11329; "Homo sapiens (Human)" 0.832823 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 0.818042 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9H1R3 "Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK2 85366; "Homo sapiens (Human)" 0.816559 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O15111 "Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" CHUK 1147; "Homo sapiens (Human)" 0.800571 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q86YV6 "Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK4 340156; "Homo sapiens (Human)" 0.796576 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P78356 "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta)" PIP4K2B 8396; "Homo sapiens (Human)" 0.76558 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q07002 "Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK18 5129; "Homo sapiens (Human)" 0.734262 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9NRM7 "Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS2 26524; "Homo sapiens (Human)" 0.732832 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 0.714258 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 0.708582 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q16512 "Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN1 5585; "Homo sapiens (Human)" 0.676695 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q96BR1 "Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK3 100533105;23678; "Homo sapiens (Human)" 0.658367 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q13523 "Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" PRPF4B 8899; "Homo sapiens (Human)" 0.643779 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 0.627862 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q8IY84 "Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" NIM1K 167359; "Homo sapiens (Human)" 0.626286 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q02779 "Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K10 4294; "Homo sapiens (Human)" 0.573407 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q92630 "Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK2 8445; "Homo sapiens (Human)" 0.552605 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 0.546197 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 O60331 "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma)" PIP5K1C 23396; "Homo sapiens (Human)" 0.422027 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q8NFD2 "Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" ANKK1 255239; "Homo sapiens (Human)" 0.389626 Known 21 CHEMBL522892 CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2 Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 0.328741 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 4.6718 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 3.7516 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q00536 "Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK16 5127; "Homo sapiens (Human)" 3.45839 1 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 3.20594 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 3.14711 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q15139 "Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD1 5587; "Homo sapiens (Human)" 3.09068 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q00537 "Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK17 5128; "Homo sapiens (Human)" 3.08757 2 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 3.07719 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 2.91662 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 2.8963 3 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 2.867 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 2.86374 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 2.8367 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 2.81465 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 2.80955 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 2.76227 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P22455 "Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR4 2264; "Homo sapiens (Human)" 2.72385 4 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 2.66778 5 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 2.64549 6 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 2.62793 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P36639 "7,8-dihydro-8-oxoguanine triphosphatase (EC 3.6.1.55) (2-hydroxy-dATP diphosphatase) (EC 3.6.1.56) (8-oxo-dGTPase) (Nucleoside diphosphate-linked moiety X motif 1) (Nudix motif 1)" "Nudix hydrolase family" NUDT1 4521; "Homo sapiens (Human)" 2.59556 7 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 2.59203 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 2.55114 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 2.54052 8 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 2.48964 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 2.47446 9 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 2.45317 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 2.44355 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 2.43359 10 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 2.42735 11 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 2.41827 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 2.40494 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 2.4029 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 2.39459 12 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 2.37183 13 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 2.36464 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 2.35027 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 2.33379 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 2.32134 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 2.29899 14 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O76039 "Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL5 6792; "Homo sapiens (Human)" 2.29289 15 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 2.24352 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 2.23215 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 2.22552 16 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 2.19934 17 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O14936 "Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; MAGUK family" CASK 8573; "Homo sapiens (Human)" 2.17879 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 2.15416 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 2.12313 18 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9UQ88 "Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 2) (Cell division protein kinase 11A) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK11A 728642; "Homo sapiens (Human)" 2.11423 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 2.09898 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O43353 "Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK2 8767; "Homo sapiens (Human)" 2.0967 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 2.07834 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 2.07181 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 2.06071 19 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 2.04839 20 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 2.03532 21 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 2.03085 22 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 2.02291 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 2.02104 23 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 2.00696 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 2.00335 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q13164 "Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK7 5598; "Homo sapiens (Human)" 2.00114 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.00079 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P21127 "Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK11B 984; "Homo sapiens (Human)" 1.9713 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P37023 "Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVRL1 94; "Homo sapiens (Human)" 1.96575 24 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P53671 "LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK2 3985; "Homo sapiens (Human)" 1.96045 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 1.95755 25 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 1.94085 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 1.92152 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O94921 "Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK14 5218; "Homo sapiens (Human)" 1.91736 26 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.91266 27 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.90255 28 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.89307 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.88768 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 1.88138 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q13546 "Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK1 8737; "Homo sapiens (Human)" 1.87595 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 1.87352 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.86896 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P51955 "Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK2 4751; "Homo sapiens (Human)" 1.86757 29 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 1.86598 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 1.8602 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 1.85089 30 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P54764 "Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA4 2043; "Homo sapiens (Human)" 1.84737 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 1.83467 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q96Q40 "Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK15 65061; "Homo sapiens (Human)" 1.82375 31 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 1.82131 32 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 1.80025 33 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O95497 "Pantetheinase (EC 3.5.1.92) (Pantetheine hydrolase) (Tiff66) (Vascular non-inflammatory molecule 1) (Vanin-1)" "Carbon-nitrogen hydrolase superfamily, BTD/VNN family" VNN1 8876; "Homo sapiens (Human)" 1.77572 34 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 1.77084 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.76726 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 1.75366 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.74785 35 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 1.7469 36 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P49674 "Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1E 102800317;1454; "Homo sapiens (Human)" 1.72798 37 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 1.72527 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 1.72474 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 1.69319 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 1.68575 38 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.68347 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 1.66914 39 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 1.66732 40 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q07002 "Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK18 5129; "Homo sapiens (Human)" 1.6531 41 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 1.65199 42 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O15146 "Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)" "Protein kinase superfamily, Tyr protein kinase family" MUSK 4593; "Homo sapiens (Human)" 1.63424 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.63363 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 1.61997 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P21860 "Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB3 2065; "Homo sapiens (Human)" 1.61559 43 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 1.61249 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 1.61067 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 1.6049 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 1.58917 44 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q00526 "Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK3 1018; "Homo sapiens (Human)" 1.57832 45 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9BWU1 "Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK19 23097; "Homo sapiens (Human)" 1.5751 46 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 1.57312 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 1.57268 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 1.55913 47 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q15759 "Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK11 5600; "Homo sapiens (Human)" 1.55749 48 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 1.5571 49 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.55154 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.5376 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 1.53722 50 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 1.49763 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q15375 "Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA7 2045; "Homo sapiens (Human)" 1.47608 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 1.46089 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 1.4477 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.44709 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 1.44504 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q6XUX3 "Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)" "Protein kinase superfamily, Ser/Thr protein kinase family" DSTYK 25778; "Homo sapiens (Human)" 1.40808 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P36896 "Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1B 91; "Homo sapiens (Human)" 1.40483 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q15569 "Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" TESK1 7016; "Homo sapiens (Human)" 1.38786 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 1.37896 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 1.36738 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q52WX2 "Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" SBK1 388228; "Homo sapiens (Human)" 1.34635 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q02763 "Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TEK 7010; "Homo sapiens (Human)" 1.32621 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 1.31756 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 1.31092 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.30718 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.30343 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 1.3005 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 1.28268 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 1.28115 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P14616 "Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSRR 3645; "Homo sapiens (Human)" 1.27471 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 1.27432 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q59H18 "Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" TNNI3K 100526835;51086; "Homo sapiens (Human)" 1.27191 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q92772 "Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL2 8999; "Homo sapiens (Human)" 1.26625 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.25108 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 1.24352 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q8TD19 "Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK9 91754; "Homo sapiens (Human)" 1.23221 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.22004 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 1.20425 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 1.18349 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 1.14404 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 1.13565 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 1.11185 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q6ZN16 "Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K15 389840; "Homo sapiens (Human)" 1.10288 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 1.09539 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P0C264 "Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family member 3) (Sugen kinase 110)" "Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamily" SBK3 100130827; "Homo sapiens (Human)" 1.09452 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 1.08607 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.07784 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 1.02311 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 1.02023 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 1.0102 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q09013 "Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) (DMPK) (Myotonic dystrophy protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" DMPK 1760; "Homo sapiens (Human)" 0.996439 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O15075 "Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK1 9201; "Homo sapiens (Human)" 0.993207 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 0.989134 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 0.982275 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q8NFD2 "Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" ANKK1 255239; "Homo sapiens (Human)" 0.973751 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P19525 "Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK2 5610; "Homo sapiens (Human)" 0.954185 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q8N568 "Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin domain-containing protein 3B) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK2 166614; "Homo sapiens (Human)" 0.879431 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P57078 "Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK4 "Homo sapiens (Human)" 0.876998 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9BRS2 "Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK1 83732; "Homo sapiens (Human)" 0.873215 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 0.865166 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 0.844313 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q96D53 "Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase 4) (Coenzyme Q protein 8B)" "Protein kinase superfamily, ADCK protein kinase family" COQ8B 79934; "Homo sapiens (Human)" 0.832916 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 0.826218 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 0.813729 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O14920 "Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKB 3551; "Homo sapiens (Human)" 0.806776 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P43403 "Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" ZAP70 7535; "Homo sapiens (Human)" 0.804406 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q96SB4 "SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK1 6732; "Homo sapiens (Human)" 0.795537 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q8TDX7 "Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK7 140609; "Homo sapiens (Human)" 0.79185 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P54756 "Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA5 2044; "Homo sapiens (Human)" 0.788276 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 0.72934 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 0.698646 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 O14730 "Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK3 8780; "Homo sapiens (Human)" 0.672853 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 0.669147 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q99755 "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)" PIP5K1A 8394; "Homo sapiens (Human)" 0.658815 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 0.573796 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 0.505446 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q13233 "Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K1 4214; "Homo sapiens (Human)" 0.49232 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 0.482296 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 0.476494 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 0.475306 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q8IY84 "Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" NIM1K 167359; "Homo sapiens (Human)" 0.474989 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 P36897 "TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR1 7046; "Homo sapiens (Human)" 0.43498 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q92630 "Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK2 8445; "Homo sapiens (Human)" 0.425676 Known 22 CHEMBL601719 C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1 Q9P289 "Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK26 51765; "Homo sapiens (Human)" 0.376717 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 3.40081 1 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 3.13448 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.93551 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 2.66341 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 2.61123 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q92731 "Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)" "Nuclear hormone receptor family, NR3 subfamily" ESR2 2100; "Homo sapiens (Human)" 2.58797 2 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 2.58665 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 2.55765 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P42680 "Tyrosine-protein kinase Tec (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TEC 7006; "Homo sapiens (Human)" 2.52877 3 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 2.50472 4 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P42345 "Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)" "PI3/PI4-kinase family" MTOR 2475; "Homo sapiens (Human)" 2.4771 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9Y463 "Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1B 9149; "Homo sapiens (Human)" 2.43301 5 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 2.43151 6 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 2.4196 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 2.3976 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 2.37799 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O00750 "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta)" "PI3/PI4-kinase family" PIK3C2B 5287; "Homo sapiens (Human)" 2.36296 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 2.3555 7 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O43353 "Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK2 8767; "Homo sapiens (Human)" 2.32646 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 2.32425 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 2.29744 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O00329 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)" "PI3/PI4-kinase family" PIK3CD 5293; "Homo sapiens (Human)" 2.2427 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 2.23879 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 2.22732 8 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 2.22687 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 2.21742 9 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 2.21583 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P03372 "Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)" "Nuclear hormone receptor family, NR3 subfamily" ESR1 2099; "Homo sapiens (Human)" 2.18084 10 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 2.17447 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 2.15766 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 2.15575 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P21860 "Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB3 2065; "Homo sapiens (Human)" 2.1534 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 2.125 11 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P78527 "DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)" "PI3/PI4-kinase family" PRKDC 5591; "Homo sapiens (Human)" 2.10681 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O00311 "Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamily" CDC7 8317; "Homo sapiens (Human)" 2.09708 12 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 2.09208 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 2.07701 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P04049 "RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" RAF1 5894; "Homo sapiens (Human)" 2.05192 13 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 2.04696 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 2.03422 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q32MK0 "Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK3 91807; "Homo sapiens (Human)" 2.02265 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P36897 "TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR1 7046; "Homo sapiens (Human)" 2.00872 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 1.9786 14 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 1.97726 15 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P24723 "Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCH 5583; "Homo sapiens (Human)" 1.97314 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 1.97063 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 1.96627 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 1.9591 16 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.94907 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 1.93649 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 1.93408 17 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 1.91996 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P36894 "Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1A 657; "Homo sapiens (Human)" 1.91902 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.91725 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.90074 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 1.90029 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q15139 "Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD1 5587; "Homo sapiens (Human)" 1.89914 18 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q13237 "cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG2 5593; "Homo sapiens (Human)" 1.89732 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9BWU1 "Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK19 23097; "Homo sapiens (Human)" 1.89328 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 1.88982 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P37023 "Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVRL1 94; "Homo sapiens (Human)" 1.88505 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q13546 "Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK1 8737; "Homo sapiens (Human)" 1.87613 19 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 1.86814 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 1.86567 20 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 1.85089 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.85027 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P42336 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)" "PI3/PI4-kinase family" PIK3CA 5290; "Homo sapiens (Human)" 1.84534 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q13873 "Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR2 659; "Homo sapiens (Human)" 1.82779 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9P286 "Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK5 57144; "Homo sapiens (Human)" 1.80939 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P48736 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)" "PI3/PI4-kinase family" PIK3CG 5294; "Homo sapiens (Human)" 1.8057 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q02156 "Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCE 5581; "Homo sapiens (Human)" 1.80315 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 1.80238 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q92772 "Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL2 8999; "Homo sapiens (Human)" 1.80181 21 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P22455 "Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR4 2264; "Homo sapiens (Human)" 1.79664 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O75747 "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma (PI3K-C2-gamma) (PtdIns-3-kinase C2 subunit gamma) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-gamma)" "PI3/PI4-kinase family" PIK3C2G 5288; "Homo sapiens (Human)" 1.78776 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 1.78699 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 1.76409 22 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 1.75836 23 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P36896 "Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1B 91; "Homo sapiens (Human)" 1.75301 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 1.74443 24 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 1.74373 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 1.74102 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9UBF8 "Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) (NPIK) (PI4K92)" "PI3/PI4-kinase family, Type III PI4K subfamily" PI4KB 5298; "Homo sapiens (Human)" 1.73266 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 1.72356 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 1.72162 25 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 1.71334 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 1.71118 26 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9C098 "Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK3 85443; "Homo sapiens (Human)" 1.70866 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 1.70679 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 1.70206 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 1.69435 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 1.69406 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P41240 "Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" CSK 1445; "Homo sapiens (Human)" 1.68303 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 1.67022 27 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 1.64836 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 1.64044 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 1.64001 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 1.6252 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 1.58632 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 1.5802 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P54764 "Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA4 2043; "Homo sapiens (Human)" 1.57512 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q15759 "Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK11 5600; "Homo sapiens (Human)" 1.57368 28 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 1.55755 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q8TDC3 "Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK1 84446; "Homo sapiens (Human)" 1.54764 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.546 29 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P54756 "Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA5 2044; "Homo sapiens (Human)" 1.54506 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P49674 "Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1E 102800317;1454; "Homo sapiens (Human)" 1.53654 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 1.5365 30 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.53179 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 1.52501 31 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 1.51457 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O76039 "Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL5 6792; "Homo sapiens (Human)" 1.51163 32 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 1.50797 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.50643 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P00374 "Dihydrofolate reductase (EC 1.5.1.3)" "Dihydrofolate reductase family" DHFR 1719; "Homo sapiens (Human)" 1.50641 33 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 1.50342 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P29323 "Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB2 2048; "Homo sapiens (Human)" 1.50001 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 1.48966 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 1.485 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P0C1S8 "Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) (Wee1B kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE2 494551; "Homo sapiens (Human)" 1.48448 34 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 1.47523 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 1.44965 35 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9UIK4 "Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK2 23604; "Homo sapiens (Human)" 1.44191 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 1.4292 36 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.42142 37 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9NQU5 "Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) (PAK-6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK6 106821730;56924; "Homo sapiens (Human)" 1.41968 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.41687 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9BX84 "Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6)" "Protein kinase superfamily, Alpha-type protein kinase family, ALPK subfamily; Transient receptor (TC 1.A.4) family, LTrpC subfamily, TRPM6 sub-subfamily" TRPM6 140803; "Homo sapiens (Human)" 1.41257 38 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q09013 "Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) (DMPK) (Myotonic dystrophy protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" DMPK 1760; "Homo sapiens (Human)" 1.40786 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 1.40152 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 1.39911 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 1.39395 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 1.39184 39 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 1.38924 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P27037 "Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2A 92; "Homo sapiens (Human)" 1.38648 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P48729 "Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1 1452; "Homo sapiens (Human)" 1.38593 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 1.36765 40 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O60331 "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma)" PIP5K1C 23396; "Homo sapiens (Human)" 1.36095 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9UBE8 "Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" NLK 51701; "Homo sapiens (Human)" 1.36055 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 1.35873 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q13705 "Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2B 93; "Homo sapiens (Human)" 1.35196 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 1.3516 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 1.34769 41 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 1.32747 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.32225 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 1.31648 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O15146 "Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)" "Protein kinase superfamily, Tyr protein kinase family" MUSK 4593; "Homo sapiens (Human)" 1.30134 42 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q04759 "Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCQ 5588; "Homo sapiens (Human)" 1.2992 43 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 1.28446 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q92630 "Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK2 8445; "Homo sapiens (Human)" 1.28365 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 1.27364 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 1.27336 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 1.26867 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 1.26611 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.26459 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q8IWQ3 "Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 2) (BR serine/threonine-protein kinase 2) (Serine/threonine-protein kinase 29) (Serine/threonine-protein kinase SAD-A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK2 9024; "Homo sapiens (Human)" 1.25042 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 1.24584 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 1.24487 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 1.24044 44 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P54753 "Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) (EPH-like kinase 2) (Embryonic kinase 2) (EK2) (hEK2) (Tyrosine-protein kinase TYRO6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB3 2049; "Homo sapiens (Human)" 1.2374 45 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 1.23646 46 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P17252 "Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCA 5578; "Homo sapiens (Human)" 1.22932 47 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.22836 48 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P57078 "Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK4 "Homo sapiens (Human)" 1.2266 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 1.20005 49 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 1.19957 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.19586 50 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 1.19163 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O14936 "Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; MAGUK family" CASK 8573; "Homo sapiens (Human)" 1.17795 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 1.17761 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 1.17371 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.17272 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q8TBX8 "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma)" PIP4K2C 79837; "Homo sapiens (Human)" 1.14781 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.1262 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q8NI60 "Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (Coenzyme Q protein 8A) (aarF domain-containing protein kinase 3)" "Protein kinase superfamily, ADCK protein kinase family" COQ8A 56997; "Homo sapiens (Human)" 1.12542 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9NYY3 "Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) (Serine/threonine-protein kinase SNK) (hSNK) (Serum-inducible kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK2 10769; "Homo sapiens (Human)" 1.12517 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P53355 "Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK1 1612; "Homo sapiens (Human)" 1.11938 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 1.11893 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q6XUX3 "Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)" "Protein kinase superfamily, Ser/Thr protein kinase family" DSTYK 25778; "Homo sapiens (Human)" 1.11504 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P42338 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta)" "PI3/PI4-kinase family" PIK3CB 5291; "Homo sapiens (Human)" 1.115 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 1.11334 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 1.108 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q8WTQ7 "Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK7 131890; "Homo sapiens (Human)" 1.10694 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 1.09923 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 1.0867 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q59H18 "Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" TNNI3K 100526835;51086; "Homo sapiens (Human)" 1.08098 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O96013 "Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK4 10298; "Homo sapiens (Human)" 1.07397 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 1.06136 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 1.06026 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 1.04812 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 1.04537 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 1.04361 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 1.03487 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 1.02822 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 1.01168 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 1.00651 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 1.0048 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.00033 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q15835 "Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK1 6011; "Homo sapiens (Human)" 0.992751 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 0.971514 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P37173 "TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR2 7048; "Homo sapiens (Human)" 0.971318 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 0.965264 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 0.949815 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q15569 "Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" TESK1 7016; "Homo sapiens (Human)" 0.937714 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 0.924922 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 0.91374 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 0.90795 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 0.900576 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 0.893418 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9UQM7 "Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2A 815; "Homo sapiens (Human)" 0.886246 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q13177 "Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK2 5062; "Homo sapiens (Human)" 0.881518 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P11309 "Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM1 5292; "Homo sapiens (Human)" 0.871434 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q8NFD2 "Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" ANKK1 255239; "Homo sapiens (Human)" 0.862672 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 0.854948 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 0.850164 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 0.848703 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9BVS4 "Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK2 55781; "Homo sapiens (Human)" 0.842679 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 0.820233 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 0.817349 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P45985 "Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K4 6416; "Homo sapiens (Human)" 0.808544 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9BUB5 "MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK1 8569; "Homo sapiens (Human)" 0.803072 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q8WU08 "Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32A 202374; "Homo sapiens (Human)" 0.799868 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9NRM7 "Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS2 26524; "Homo sapiens (Human)" 0.796984 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q13627 "Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1A 1859; "Homo sapiens (Human)" 0.788291 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 0.780919 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 0.766462 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 0.766182 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 0.76512 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O60885 "Bromodomain-containing protein 4 (Protein HUNK1)" BRD4 23476; "Homo sapiens (Human)" 0.755597 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q8NEV4 "Myosin-IIIa (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3A 53904; "Homo sapiens (Human)" 0.753186 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 0.750689 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9NY57 "Serine/threonine-protein kinase 32B (EC 2.7.11.1) (Yet another novel kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32B 55351; "Homo sapiens (Human)" 0.731837 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q8N752 "Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1L 122011; "Homo sapiens (Human)" 0.727753 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 0.724072 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q7KZI7 "Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK2 2011; "Homo sapiens (Human)" 0.722016 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 0.721431 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9NUW8 "Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-)" "Tyrosyl-DNA phosphodiesterase family" TDP1 55775; "Homo sapiens (Human)" 0.721333 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9Y243 "RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT3 10000; "Homo sapiens (Human)" 0.681137 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P78368 "Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G2 1455; "Homo sapiens (Human)" 0.674135 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9H4B4 "Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3) (Proliferation-related kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK3 1263; "Homo sapiens (Human)" 0.6627 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 0.641907 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q02763 "Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TEK 7010; "Homo sapiens (Human)" 0.635473 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 0.634968 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 0.628588 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q96D53 "Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase 4) (Coenzyme Q protein 8B)" "Protein kinase superfamily, ADCK protein kinase family" COQ8B 79934; "Homo sapiens (Human)" 0.627853 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q13233 "Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K1 4214; "Homo sapiens (Human)" 0.625069 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 0.621257 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9NYL2 "Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K20 51776; "Homo sapiens (Human)" 0.611182 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C P19525 "Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK2 5610; "Homo sapiens (Human)" 0.599974 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9Y2K2 "Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK3 23387; "Homo sapiens (Human)" 0.560382 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C O94768 "Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17B 9262; "Homo sapiens (Human)" 0.492264 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9HCP0 "Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G1 53944; "Homo sapiens (Human)" 0.483637 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9P289 "Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK26 51765; "Homo sapiens (Human)" 0.460016 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q8WXR4 "Myosin-IIIb (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3B 140469; "Homo sapiens (Human)" 0.392471 Known 23 CHEMBL1241674 CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 Oc1ccc2c(c1)cc([nH]2)c1nn(c2c1c(N)ncn2)C(C)C Q9Y6M4 "Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G3 1456; "Homo sapiens (Human)" 0.339684 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 3.80739 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 3.59859 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 3.18604 1 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 3.106 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 3.07502 2 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 3.0053 3 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 2.97256 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 2.90484 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P42229 "Signal transducer and activator of transcription 5A" "Transcription factor STAT family" STAT5A 6776; "Homo sapiens (Human)" 2.89784 4 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 2.8611 5 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 2.77127 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 2.74681 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 2.71363 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 2.67391 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P30291 "Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE1 7465; "Homo sapiens (Human)" 2.6708 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 2.58537 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 2.57431 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 2.55244 6 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 2.51846 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 2.45722 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 2.45507 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 2.43799 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 2.4028 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 2.39425 7 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 2.38224 8 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 2.36716 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 2.36268 9 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 2.35107 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 2.34163 10 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 2.28979 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 2.28864 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 2.28287 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 2.25244 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 2.23643 11 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 2.22865 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 2.22666 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 2.22397 12 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 2.22064 13 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 2.19982 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 2.18876 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 2.18457 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 2.18009 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 2.17968 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 2.17632 14 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P0C1S8 "Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) (Wee1B kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE2 494551; "Homo sapiens (Human)" 2.14021 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 2.1354 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P04049 "RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" RAF1 5894; "Homo sapiens (Human)" 2.1282 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 2.12551 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 2.12501 15 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 2.11037 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 2.10944 16 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O75914 "Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK3 5063; "Homo sapiens (Human)" 2.09884 17 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 2.08898 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 2.08433 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 2.04492 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P21860 "Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB3 2065; "Homo sapiens (Human)" 2.03752 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q15759 "Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK11 5600; "Homo sapiens (Human)" 2.03231 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 2.02131 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 1.99826 18 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 1.99204 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.9904 19 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P22455 "Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR4 2264; "Homo sapiens (Human)" 1.98015 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.96087 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 1.95969 20 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9UBE8 "Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" NLK 51701; "Homo sapiens (Human)" 1.95602 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 1.95037 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 1.94804 21 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9NZJ5 "Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK3 9451; "Homo sapiens (Human)" 1.92704 22 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 1.91038 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 1.87603 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 1.86117 23 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 1.8598 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 1.85909 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9P2K8 "eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK4 440275; "Homo sapiens (Human)" 1.85852 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 1.85001 24 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P37023 "Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVRL1 94; "Homo sapiens (Human)" 1.84058 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.82589 25 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 1.81216 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 1.81199 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 1.80197 26 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 1.79537 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 1.7898 27 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 1.78072 28 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 1.76726 29 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 1.75672 30 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q96D53 "Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase 4) (Coenzyme Q protein 8B)" "Protein kinase superfamily, ADCK protein kinase family" COQ8B 79934; "Homo sapiens (Human)" 1.7526 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 1.75089 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 1.74923 31 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q99640 "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" PKMYT1 9088; "Homo sapiens (Human)" 1.74139 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 1.73835 32 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.7298 33 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.72825 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 1.71474 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q32MK0 "Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK3 91807; "Homo sapiens (Human)" 1.70644 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q01538 "Myelin transcription factor 1 (MyT1) (Myelin transcription factor I) (MyTI) (PLPB1) (Proteolipid protein-binding protein)" "MYT1 family" MYT1 4661; "Homo sapiens (Human)" 1.7047 34 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 1.70469 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.70183 35 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q13153 "Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK1 5058; "Homo sapiens (Human)" 1.69802 36 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 1.68608 37 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 1.68093 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 1.67409 38 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P54753 "Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) (EPH-like kinase 2) (Embryonic kinase 2) (EK2) (hEK2) (Tyrosine-protein kinase TYRO6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB3 2049; "Homo sapiens (Human)" 1.67286 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.61312 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.61238 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O43353 "Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK2 8767; "Homo sapiens (Human)" 1.60297 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 1.60255 39 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 1.59483 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 1.58629 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P54764 "Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA4 2043; "Homo sapiens (Human)" 1.58593 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 1.56154 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q13705 "Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2B 93; "Homo sapiens (Human)" 1.56055 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.55624 40 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 1.54999 41 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P29323 "Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB2 2048; "Homo sapiens (Human)" 1.54233 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 1.54201 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 1.53487 42 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 1.5336 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q02779 "Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K10 4294; "Homo sapiens (Human)" 1.53359 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O15146 "Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)" "Protein kinase superfamily, Tyr protein kinase family" MUSK 4593; "Homo sapiens (Human)" 1.52789 43 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 1.52753 44 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 1.52591 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 1.52158 45 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.50957 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 1.5048 46 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.49787 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q00536 "Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK16 5127; "Homo sapiens (Human)" 1.49253 47 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.48724 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.48173 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q13557 "Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2D 817; "Homo sapiens (Human)" 1.46112 48 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 1.45679 49 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 1.45645 50 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q8TBX8 "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma)" PIP4K2C 79837; "Homo sapiens (Human)" 1.43755 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P27448 "MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK3 4140; "Homo sapiens (Human)" 1.43269 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 1.40965 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q15569 "Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" TESK1 7016; "Homo sapiens (Human)" 1.40649 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 1.39284 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 1.38417 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 1.37879 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9NRP7 "Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK36 27148; "Homo sapiens (Human)" 1.37781 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P36894 "Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1A 657; "Homo sapiens (Human)" 1.36764 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 1.35917 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q02763 "Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TEK 7010; "Homo sapiens (Human)" 1.3554 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.3544 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 1.35218 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 1.34336 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P51955 "Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK2 4751; "Homo sapiens (Human)" 1.33965 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q59H18 "Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" TNNI3K 100526835;51086; "Homo sapiens (Human)" 1.32006 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P54756 "Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA5 2044; "Homo sapiens (Human)" 1.29377 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P37173 "TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR2 7048; "Homo sapiens (Human)" 1.29377 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P36896 "Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1B 91; "Homo sapiens (Human)" 1.29087 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 1.27877 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 1.25913 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 1.25547 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P41240 "Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" CSK 1445; "Homo sapiens (Human)" 1.2479 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 1.24014 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.22369 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 1.20159 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 1.18434 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P53671 "LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK2 3985; "Homo sapiens (Human)" 1.18251 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.17589 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 1.15795 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 1.15278 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.13889 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P45985 "Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K4 6416; "Homo sapiens (Human)" 1.12624 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 1.10749 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q7KZI7 "Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK2 2011; "Homo sapiens (Human)" 1.1056 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9Y6R4 "Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K4 4216; "Homo sapiens (Human)" 1.10343 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.0867 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q8TDC3 "Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK1 84446; "Homo sapiens (Human)" 1.08634 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q8NI60 "Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (Coenzyme Q protein 8A) (aarF domain-containing protein kinase 3)" "Protein kinase superfamily, ADCK protein kinase family" COQ8A 56997; "Homo sapiens (Human)" 1.06599 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P42680 "Tyrosine-protein kinase Tec (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TEC 7006; "Homo sapiens (Human)" 1.06433 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P0C264 "Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family member 3) (Sugen kinase 110)" "Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamily" SBK3 100130827; "Homo sapiens (Human)" 1.05761 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q8NG66 "Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK11 79858; "Homo sapiens (Human)" 1.04145 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 1.03948 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 1.02799 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9NY57 "Serine/threonine-protein kinase 32B (EC 2.7.11.1) (Yet another novel kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32B 55351; "Homo sapiens (Human)" 1.02354 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q8WU08 "Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32A 202374; "Homo sapiens (Human)" 1.02263 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9Y2K2 "Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK3 23387; "Homo sapiens (Human)" 1.00515 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 0.986336 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 0.97901 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q6P3R8 "Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase 5) (NimA-related protein kinase 5)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK5 341676; "Homo sapiens (Human)" 0.96907 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9NYL2 "Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K20 51776; "Homo sapiens (Human)" 0.94163 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q6DT37 "Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (MRCKG) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPG 55561; "Homo sapiens (Human)" 0.911292 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P36897 "TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR1 7046; "Homo sapiens (Human)" 0.886181 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P27037 "Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2A 92; "Homo sapiens (Human)" 0.823405 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q96PY6 "Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK1 4750; "Homo sapiens (Human)" 0.818233 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9Y5S2 "Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (CDC42BP-beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPB 9578; "Homo sapiens (Human)" 0.810085 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 0.800165 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 0.795511 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9H4B4 "Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3) (Proliferation-related kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK3 1263; "Homo sapiens (Human)" 0.795452 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9H1R3 "Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK2 85366; "Homo sapiens (Human)" 0.773426 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q8IWQ3 "Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 2) (BR serine/threonine-protein kinase 2) (Serine/threonine-protein kinase 29) (Serine/threonine-protein kinase SAD-A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK2 9024; "Homo sapiens (Human)" 0.723025 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q5VT25 "Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPA 8476; "Homo sapiens (Human)" 0.696515 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P52564 "Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6) (Stress-activated protein kinase kinase 3) (SAPK kinase 3) (SAPKK-3) (SAPKK3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K6 5608; "Homo sapiens (Human)" 0.598338 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q16659 "Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK6 5597; "Homo sapiens (Human)" 0.561496 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9Y6E0 "Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK24 8428; "Homo sapiens (Human)" 0.558446 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl P31152 "Mitogen-activated protein kinase 4 (MAP kinase 4) (MAPK 4) (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK4 5596; "Homo sapiens (Human)" 0.497249 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q9P289 "Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK26 51765; "Homo sapiens (Human)" 0.495591 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q8IY84 "Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" NIM1K 167359; "Homo sapiens (Human)" 0.432882 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl Q13546 "Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK1 8737; "Homo sapiens (Human)" 0.271072 Known 24 CHEMBL386051 CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CSc1cccc(c1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl O00506 "Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK25 10494; "Homo sapiens (Human)" 0.215195 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 3.32754 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 3.20897 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 3.17811 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 3.09733 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 3.0612 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 3.00614 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 2.87985 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 2.87183 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 2.85663 1 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q02763 "Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TEK 7010; "Homo sapiens (Human)" 2.81536 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 2.74353 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 2.55754 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 2.45264 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 2.44534 2 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 2.44089 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 2.42451 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 2.42196 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.41225 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 2.41092 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 2.4077 3 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 2.40111 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 2.39935 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 2.39736 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 2.35321 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 2.34737 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P29323 "Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB2 2048; "Homo sapiens (Human)" 2.34559 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 2.29802 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 2.28561 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 2.24278 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 2.23255 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 2.17849 4 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 2.1669 5 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 2.16413 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 2.14897 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 2.1479 6 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 2.14721 7 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 2.13638 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 2.12949 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 2.10171 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 2.08531 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 2.07867 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 2.06742 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q00526 "Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK3 1018; "Homo sapiens (Human)" 2.05621 8 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 2.04083 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 2.03632 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 2.03039 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 2.0226 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 2.02064 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 2.00086 9 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P04049 "RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" RAF1 5894; "Homo sapiens (Human)" 1.98261 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P54764 "Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA4 2043; "Homo sapiens (Human)" 1.92964 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P21860 "Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB3 2065; "Homo sapiens (Human)" 1.92939 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 1.90547 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.89663 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 1.8886 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 1.87942 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 1.86879 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.85838 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 1.82071 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 1.81868 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 1.79769 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.78997 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 1.78556 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 1.76067 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q15759 "Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK11 5600; "Homo sapiens (Human)" 1.75333 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 1.74614 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 1.74332 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 1.74051 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 1.72882 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P22455 "Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR4 2264; "Homo sapiens (Human)" 1.72354 10 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 1.70624 11 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.70036 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 1.69371 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 1.68376 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 1.68302 12 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P54756 "Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA5 2044; "Homo sapiens (Human)" 1.67744 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.67686 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P09960 "Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)" "Peptidase M1 family" LTA4H 4048; "Homo sapiens (Human)" 1.67617 13 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 1.6684 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 1.6446 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.62228 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 1.61908 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 1.6152 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O14920 "Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKB 3551; "Homo sapiens (Human)" 1.60637 14 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.60059 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 1.59447 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9P289 "Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK26 51765; "Homo sapiens (Human)" 1.57884 15 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 1.57865 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q5VT25 "Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPA 8476; "Homo sapiens (Human)" 1.57145 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 1.56587 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 1.56075 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 1.55489 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.55471 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 1.54198 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q99835 "Smoothened homolog (SMO) (Protein Gx)" "G-protein coupled receptor Fz/Smo family" SMO 6608; "Homo sapiens (Human)" 1.53813 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 1.53506 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9NWT8 "Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, mitochondrial) (MRP-S38) (Mitochondrial small ribosomal subunit protein mS38)" "Mitochondrion-specific ribosomal protein mS38 family" AURKAIP1 54998; "Homo sapiens (Human)" 1.52482 16 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9BVS4 "Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK2 55781; "Homo sapiens (Human)" 1.52474 17 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 1.51898 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P48729 "Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1 1452; "Homo sapiens (Human)" 1.51262 18 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q13546 "Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK1 8737; "Homo sapiens (Human)" 1.50478 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P08908 "5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)" "G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamily" HTR1A 3350; "Homo sapiens (Human)" 1.48595 19 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 1.4773 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.47603 20 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 1.47401 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.46383 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 1.46217 21 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9P2K8 "eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK4 440275; "Homo sapiens (Human)" 1.4613 22 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q8TD08 "Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK15 225689; "Homo sapiens (Human)" 1.45875 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O15146 "Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)" "Protein kinase superfamily, Tyr protein kinase family" MUSK 4593; "Homo sapiens (Human)" 1.44875 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q96D53 "Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase 4) (Coenzyme Q protein 8B)" "Protein kinase superfamily, ADCK protein kinase family" COQ8B 79934; "Homo sapiens (Human)" 1.44191 23 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 1.44124 24 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P20794 "Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" MAK 4117; "Homo sapiens (Human)" 1.43849 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9NYL2 "Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K20 51776; "Homo sapiens (Human)" 1.43727 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9Y2K2 "Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK3 23387; "Homo sapiens (Human)" 1.43612 25 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q15375 "Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA7 2045; "Homo sapiens (Human)" 1.4275 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P14616 "Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSRR 3645; "Homo sapiens (Human)" 1.42742 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P51955 "Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK2 4751; "Homo sapiens (Human)" 1.42355 26 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 1.42302 27 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P41240 "Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" CSK 1445; "Homo sapiens (Human)" 1.40136 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P10275 "Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)" "Nuclear hormone receptor family, NR3 subfamily" AR 367; "Homo sapiens (Human)" 1.40103 28 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 1.39642 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 1.37236 29 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.37211 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P54753 "Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) (EPH-like kinase 2) (Embryonic kinase 2) (EK2) (hEK2) (Tyrosine-protein kinase TYRO6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB3 2049; "Homo sapiens (Human)" 1.3591 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 1.35897 30 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.3402 31 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 1.32964 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9UIK4 "Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK2 23604; "Homo sapiens (Human)" 1.31903 32 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 1.30751 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.30056 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P57078 "Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK4 "Homo sapiens (Human)" 1.29934 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 1.29679 33 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.29272 34 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 1.28927 35 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 1.28567 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 1.2813 36 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 1.26441 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 1.25709 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q92772 "Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL2 8999; "Homo sapiens (Human)" 1.24107 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 1.23405 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 1.22641 37 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.22301 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q8TBX8 "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma)" PIP4K2C 79837; "Homo sapiens (Human)" 1.21696 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 1.21688 38 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 1.21154 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.20964 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 1.20782 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O14730 "Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK3 8780; "Homo sapiens (Human)" 1.2067 39 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 1.19954 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 1.19925 40 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 1.19048 41 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9H1R3 "Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK2 85366; "Homo sapiens (Human)" 1.18935 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q32MK0 "Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK3 91807; "Homo sapiens (Human)" 1.18793 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O43353 "Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK2 8767; "Homo sapiens (Human)" 1.17889 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 1.17873 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9BWU1 "Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK19 23097; "Homo sapiens (Human)" 1.17247 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P50406 "5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)" "G-protein coupled receptor 1 family" HTR6 3362; "Homo sapiens (Human)" 1.16632 42 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P28482 "Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK1 5594; "Homo sapiens (Human)" 1.16629 43 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 1.15932 44 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.15394 45 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 1.15075 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.15 46 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 1.14487 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 1.14285 47 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9Y463 "Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1B 9149; "Homo sapiens (Human)" 1.14121 48 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 1.12983 49 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q59H18 "Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" TNNI3K 100526835;51086; "Homo sapiens (Human)" 1.11329 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 1.11195 50 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 1.11157 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 1.10844 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 1.10619 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q8TD19 "Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK9 91754; "Homo sapiens (Human)" 1.10239 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O15264 "Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK13 5603; "Homo sapiens (Human)" 1.1016 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P49674 "Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1E 102800317;1454; "Homo sapiens (Human)" 1.09289 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 1.07072 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.07023 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 1.04136 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O00506 "Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK25 10494; "Homo sapiens (Human)" 1.03958 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 1.03646 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 1.01966 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 1.01903 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O94921 "Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK14 5218; "Homo sapiens (Human)" 1.00404 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 0.999769 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 0.983952 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 0.977669 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 0.977656 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 0.975605 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q96Q40 "Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK15 65061; "Homo sapiens (Human)" 0.973458 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q8IVW4 "Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine-protein kinase NKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL3 51265; "Homo sapiens (Human)" 0.95123 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q07002 "Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK18 5129; "Homo sapiens (Human)" 0.941039 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 0.935929 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 0.935837 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q00537 "Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK17 5128; "Homo sapiens (Human)" 0.932276 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9Y6R4 "Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K4 4216; "Homo sapiens (Human)" 0.915632 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P53778 "Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK12 6300; "Homo sapiens (Human)" 0.906494 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 0.89907 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 0.884314 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9UQ88 "Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 2) (Cell division protein kinase 11A) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK11A 728642; "Homo sapiens (Human)" 0.881605 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9NRP7 "Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK36 27148; "Homo sapiens (Human)" 0.877177 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 0.8625 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 0.860304 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q6XUX3 "Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)" "Protein kinase superfamily, Ser/Thr protein kinase family" DSTYK 25778; "Homo sapiens (Human)" 0.857337 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P21127 "Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK11B 984; "Homo sapiens (Human)" 0.851824 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9UBE8 "Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" NLK 51701; "Homo sapiens (Human)" 0.831689 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q15569 "Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" TESK1 7016; "Homo sapiens (Human)" 0.822575 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 0.811296 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 0.801438 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9Y5S2 "Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (CDC42BP-beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPB 9578; "Homo sapiens (Human)" 0.793789 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q02779 "Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K10 4294; "Homo sapiens (Human)" 0.793528 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O15111 "Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" CHUK 1147; "Homo sapiens (Human)" 0.79292 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 0.789975 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 0.789391 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9BQI3 "Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled repressor) (HCR) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Hemin-sensitive initiation factor 2-alpha kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK1 27102; "Homo sapiens (Human)" 0.780174 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 0.755448 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9BUB5 "MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK1 8569; "Homo sapiens (Human)" 0.752506 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 0.737156 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q00536 "Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK16 5127; "Homo sapiens (Human)" 0.732115 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q92630 "Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK2 8445; "Homo sapiens (Human)" 0.696278 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P53671 "LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK2 3985; "Homo sapiens (Human)" 0.668334 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 0.654464 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q8N5S9 "Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK1 84254; "Homo sapiens (Human)" 0.650491 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 0.644775 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 0.617595 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 0.605008 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 0.601763 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P54646 "5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA2 5563; "Homo sapiens (Human)" 0.599941 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q6DT37 "Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (MRCKG) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPG 55561; "Homo sapiens (Human)" 0.596503 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 0.594789 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 0.587522 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O75914 "Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK3 5063; "Homo sapiens (Human)" 0.544313 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P42680 "Tyrosine-protein kinase Tec (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TEC 7006; "Homo sapiens (Human)" 0.531113 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 0.524245 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q8WXR4 "Myosin-IIIb (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3B 140469; "Homo sapiens (Human)" 0.50335 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 0.495492 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O76039 "Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL5 6792; "Homo sapiens (Human)" 0.452749 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q8NFD2 "Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" ANKK1 255239; "Homo sapiens (Human)" 0.451367 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F O14578 "Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" CIT 11113; "Homo sapiens (Human)" 0.41522 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q8NEV4 "Myosin-IIIa (EC 2.7.11.1)" "TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family" MYO3A 53904; "Homo sapiens (Human)" 0.406023 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q14012 "Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1 8536; "Homo sapiens (Human)" 0.361556 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 0.312623 Known 25 CHEMBL1230609 COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 COc1cc2c(ccnc2cc1OCCCN1CCOCC1)Oc1ccc(cc1F)NC(=O)C1(CC1)C(=O)Nc1ccc(cc1)F P57058 "Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase MAK-V)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" HUNK 30811; "Homo sapiens (Human)" 0.269921 Known 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC O43570 "Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)" "Alpha-carbonic anhydrase family" CA12 771; "Homo sapiens (Human)" 3.32108 1 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 2.96413 2 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P00374 "Dihydrofolate reductase (EC 1.5.1.3)" "Dihydrofolate reductase family" DHFR 1719; "Homo sapiens (Human)" 2.61693 3 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 2.48049 4 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 2.45909 5 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 2.35477 6 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 2.26707 7 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P51679 "C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) (K5-5) (CD antigen CD194)" "G-protein coupled receptor 1 family" CCR4 1233; "Homo sapiens (Human)" 2.20143 8 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 2.17475 9 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC Q16790 "Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)" "Alpha-carbonic anhydrase family" CA9 768; "Homo sapiens (Human)" 2.14997 10 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P50406 "5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)" "G-protein coupled receptor 1 family" HTR6 3362; "Homo sapiens (Human)" 2.10582 11 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 2.0745 12 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P10275 "Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)" "Nuclear hormone receptor family, NR3 subfamily" AR 367; "Homo sapiens (Human)" 2.057 13 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 1.99936 14 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.986 15 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P42229 "Signal transducer and activator of transcription 5A" "Transcription factor STAT family" STAT5A 6776; "Homo sapiens (Human)" 1.98346 16 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 1.9597 17 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P34913 "Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]" "AB hydrolase superfamily, Epoxide hydrolase family" EPHX2 2053; "Homo sapiens (Human)" 1.94028 18 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P43166 "Carbonic anhydrase 7 (EC 4.2.1.1) (Carbonate dehydratase VII) (Carbonic anhydrase VII) (CA-VII)" "Alpha-carbonic anhydrase family" CA7 766; "Homo sapiens (Human)" 1.93382 19 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 1.92854 20 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.92422 21 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 1.91376 22 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 1.85715 23 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 1.84213 24 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 1.82068 25 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P21917 "D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)" "G-protein coupled receptor 1 family" DRD4 1815; "Homo sapiens (Human)" 1.80417 26 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 1.79912 27 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P49286 "Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)" "G-protein coupled receptor 1 family" MTNR1B 4544; "Homo sapiens (Human)" 1.75033 28 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P08908 "5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)" "G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamily" HTR1A 3350; "Homo sapiens (Human)" 1.74138 29 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC Q9ULX7 "Carbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase XIV) (CA-XIV)" "Alpha-carbonic anhydrase family" CA14 23632; "Homo sapiens (Human)" 1.73073 30 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P46098 "5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)" "Ligand-gated ion channel (TC 1.A.9) family, 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily, HTR3A sub-subfamily" HTR3A 3359; "Homo sapiens (Human)" 1.70439 31 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 1.70212 32 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P05067 "Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta A4 protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]" "APP family" APP 351; "Homo sapiens (Human)" 1.67706 33 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 1.67474 34 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 1.63462 35 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P00742 "Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]" "Peptidase S1 family" F10 2159; "Homo sapiens (Human)" 1.62651 36 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 1.58847 37 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.58299 38 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 1.54745 39 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 1.51703 40 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P10145 "Interleukin-8 (IL-8) (C-X-C motif chemokine 8) (Chemokine (C-X-C motif) ligand 8) (Emoctakin) (Granulocyte chemotactic protein 1) (GCP-1) (Monocyte-derived neutrophil chemotactic factor) (MDNCF) (Monocyte-derived neutrophil-activating peptide) (MONAP) (Neutrophil-activating protein 1) (NAP-1) (Protein 3-10C) (T-cell chemotactic factor) [Cleaved into: MDNCF-a (GCP/IL-8 protein IV) (IL8/NAP1 form I); Interleukin-8 ((Ala-IL-8)77) (GCP/IL-8 protein II) (IL-8(1-77)) (IL8/NAP1 form II) (MDNCF-b); IL-8(5-77); IL-8(6-77) ((Ser-IL-8)72) (GCP/IL-8 protein I) (IL8/NAP1 form III) (Lymphocyte-derived neutrophil-activating factor) (LYNAP) (MDNCF-c) (Neutrophil-activating factor) (NAF); IL-8(7-77) (GCP/IL-8 protein V) (IL8/NAP1 form IV); IL-8(8-77) (GCP/IL-8 protein VI) (IL8/NAP1 form V); IL-8(9-77) (GCP/IL-8 protein III) (IL8/NAP1 form VI)]" "Intercrine alpha (chemokine CxC) family" CXCL8 3576; "Homo sapiens (Human)" 1.51279 41 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.46616 42 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC Q07343 "cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.53) (DPDE4) (PDE32)" "Cyclic nucleotide phosphodiesterase family, PDE4 subfamily" PDE4B 5142; "Homo sapiens (Human)" 1.4351 43 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 1.43049 44 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 1.41906 45 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P27338 "Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B)" "Flavin monoamine oxidase family" MAOB 4129; "Homo sapiens (Human)" 1.35163 46 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC Q13639 "5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4)" "G-protein coupled receptor 1 family" HTR4 3360; "Homo sapiens (Human)" 1.34789 47 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P35354 "Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2)" "Prostaglandin G/H synthase family" PTGS2 5743; "Homo sapiens (Human)" 1.31312 48 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P27815 "cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.53) (DPDE2) (PDE46)" "Cyclic nucleotide phosphodiesterase family, PDE4 subfamily" PDE4A 5141; "Homo sapiens (Human)" 1.3022 49 26 CHEMBL1993661 CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl COc1cc(Nc2ncc(c(n2)Nc2ccccc2S(=O)(=O)NC)Cl)cc(c1OC)OC P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.2648 50 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N O43570 "Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)" "Alpha-carbonic anhydrase family" CA12 771; "Homo sapiens (Human)" 2.92248 1 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P00374 "Dihydrofolate reductase (EC 1.5.1.3)" "Dihydrofolate reductase family" DHFR 1719; "Homo sapiens (Human)" 2.75735 2 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 2.72824 3 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P11511 "Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase)" "Cytochrome P450 family" CYP19A1 1588; "Homo sapiens (Human)" 2.57757 4 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 2.45082 5 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P43166 "Carbonic anhydrase 7 (EC 4.2.1.1) (Carbonate dehydratase VII) (Carbonic anhydrase VII) (CA-VII)" "Alpha-carbonic anhydrase family" CA7 766; "Homo sapiens (Human)" 2.3975 6 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P50406 "5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)" "G-protein coupled receptor 1 family" HTR6 3362; "Homo sapiens (Human)" 2.34905 7 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P00746 "Complement factor D (EC 3.4.21.46) (Adipsin) (C3 convertase activator) (Properdin factor D)" "Peptidase S1 family" CFD 1675; "Homo sapiens (Human)" 2.18212 8 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 2.1267 9 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P42229 "Signal transducer and activator of transcription 5A" "Transcription factor STAT family" STAT5A 6776; "Homo sapiens (Human)" 2.12368 10 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 2.10705 11 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P51679 "C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) (K5-5) (CD antigen CD194)" "G-protein coupled receptor 1 family" CCR4 1233; "Homo sapiens (Human)" 2.03703 12 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 1.93888 13 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 1.93704 14 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P05067 "Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta A4 protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]" "APP family" APP 351; "Homo sapiens (Human)" 1.92438 15 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.92023 16 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P35372 "Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)" "G-protein coupled receptor 1 family" OPRM1 4988; "Homo sapiens (Human)" 1.86836 17 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 1.86479 18 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.84028 19 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.82791 20 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P10275 "Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)" "Nuclear hormone receptor family, NR3 subfamily" AR 367; "Homo sapiens (Human)" 1.78605 21 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N Q9ULX7 "Carbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase XIV) (CA-XIV)" "Alpha-carbonic anhydrase family" CA14 23632; "Homo sapiens (Human)" 1.72525 22 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P41145 "Kappa-type opioid receptor (K-OR-1) (KOR-1)" "G-protein coupled receptor 1 family" OPRK1 4986; "Homo sapiens (Human)" 1.71331 23 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P31645 "Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)" "Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamily" SLC6A4 6532; "Homo sapiens (Human)" 1.71244 24 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 1.67806 25 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P09960 "Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)" "Peptidase M1 family" LTA4H 4048; "Homo sapiens (Human)" 1.63551 26 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 1.6339 27 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P03372 "Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)" "Nuclear hormone receptor family, NR3 subfamily" ESR1 2099; "Homo sapiens (Human)" 1.59962 28 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 1.59153 29 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.5852 30 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 1.58404 31 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P00915 "Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase B) (CAB) (Carbonic anhydrase I) (CA-I)" "Alpha-carbonic anhydrase family" CA1 759; "Homo sapiens (Human)" 1.56034 32 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 1.52628 33 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P08908 "5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)" "G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamily" HTR1A 3350; "Homo sapiens (Human)" 1.50558 34 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 1.50116 35 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N Q16790 "Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)" "Alpha-carbonic anhydrase family" CA9 768; "Homo sapiens (Human)" 1.48238 36 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.46581 37 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.45856 38 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 1.45659 39 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 1.44813 40 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 1.40669 41 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P15538 "Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase) (EC 1.14.15.4)" "Cytochrome P450 family" CYP11B1 1584; "Homo sapiens (Human)" 1.38785 42 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P21917 "D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)" "G-protein coupled receptor 1 family" DRD4 1815; "Homo sapiens (Human)" 1.37834 43 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 1.34557 44 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 1.33153 45 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P00742 "Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]" "Peptidase S1 family" F10 2159; "Homo sapiens (Human)" 1.28038 46 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 1.28002 47 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P43235 "Cathepsin K (EC 3.4.22.38) (Cathepsin O) (Cathepsin O2) (Cathepsin X)" "Peptidase C1 family" CTSK 1513; "Homo sapiens (Human)" 1.26172 48 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 1.26137 49 27 CHEMBL1987034 N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 N#CCOc1ccc(cc1)Nc1nc(ncc1Br)Nc1cccc(c1)S(=O)(=O)N Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 1.2309 50 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 3.20391 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 3.13395 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 3.04541 1 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.93341 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 2.87787 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 2.87543 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 2.84889 2 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 2.83059 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 2.65004 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 2.63101 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 2.60675 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q01538 "Myelin transcription factor 1 (MyT1) (Myelin transcription factor I) (MyTI) (PLPB1) (Proteolipid protein-binding protein)" "MYT1 family" MYT1 4661; "Homo sapiens (Human)" 2.56372 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 2.5511 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 2.47651 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 2.43113 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 2.35778 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 2.31298 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 2.29853 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 2.2946 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 2.26103 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 2.25209 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 2.23904 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 2.22341 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 2.22029 3 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q15375 "Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA7 2045; "Homo sapiens (Human)" 2.21622 4 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 2.21297 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 2.1909 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 2.16296 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 2.15356 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 2.15088 5 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 2.12061 6 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q02763 "Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TEK 7010; "Homo sapiens (Human)" 2.11549 7 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q15759 "Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK11 5600; "Homo sapiens (Human)" 2.04831 8 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 2.02774 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 2.01259 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 2.00024 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.99549 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 1.99486 9 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.975 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.9637 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 1.9559 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 1.92715 10 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 1.90083 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 1.89406 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9Y2K2 "Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK3 23387; "Homo sapiens (Human)" 1.86168 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 1.85769 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 1.85243 11 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 1.82675 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.82289 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 1.81908 12 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 1.81662 13 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 1.79708 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.79461 14 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 1.74555 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 1.71875 15 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 1.69991 16 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 1.69145 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.6731 17 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 1.60718 18 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 1.60446 19 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 1.59436 20 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 1.59388 21 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 1.56743 22 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.55598 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 1.554 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 1.55198 23 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 1.55109 24 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P54753 "Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) (EPH-like kinase 2) (Embryonic kinase 2) (EK2) (hEK2) (Tyrosine-protein kinase TYRO6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB3 2049; "Homo sapiens (Human)" 1.53269 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 1.53132 25 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P78527 "DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)" "PI3/PI4-kinase family" PRKDC 5591; "Homo sapiens (Human)" 1.51803 26 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 1.49001 27 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 1.45273 28 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P34998 "Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1)" "G-protein coupled receptor 2 family" CRHR1 104909134;1394; "Homo sapiens (Human)" 1.44531 29 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 1.44188 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 1.43693 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P11309 "Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM1 5292; "Homo sapiens (Human)" 1.42103 30 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q52WX2 "Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" SBK1 388228; "Homo sapiens (Human)" 1.40832 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P29323 "Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB2 2048; "Homo sapiens (Human)" 1.40288 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 1.40156 31 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.39959 32 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 1.39839 33 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 1.39802 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 1.39504 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.38563 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.38092 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.36821 34 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.35494 35 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.34706 36 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 1.33295 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.32883 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P49674 "Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1E 102800317;1454; "Homo sapiens (Human)" 1.32621 37 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 1.32504 38 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 1.31976 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P54756 "Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA5 2044; "Homo sapiens (Human)" 1.3073 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P48449 "Lanosterol synthase (EC 5.4.99.7) (2,3-epoxysqualene--lanosterol cyclase) (Oxidosqualene--lanosterol cyclase) (OSC) (hOSC)" "Terpene cyclase/mutase family" LSS 4047; "Homo sapiens (Human)" 1.30368 39 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 1.28666 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P04049 "RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" RAF1 5894; "Homo sapiens (Human)" 1.25991 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 1.25838 40 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 1.25796 41 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 1.25191 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q8NG66 "Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK11 79858; "Homo sapiens (Human)" 1.24753 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.24714 42 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 1.23413 43 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 1.22303 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P36896 "Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1B 91; "Homo sapiens (Human)" 1.21801 44 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 1.21371 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.2085 45 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 1.20383 46 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P22455 "Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR4 2264; "Homo sapiens (Human)" 1.19869 47 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 1.19716 48 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 1.1889 49 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 1.18821 50 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P21860 "Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB3 2065; "Homo sapiens (Human)" 1.18 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 1.17865 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9NYL2 "Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K20 51776; "Homo sapiens (Human)" 1.17515 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P36894 "Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1A 657; "Homo sapiens (Human)" 1.1735 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P42680 "Tyrosine-protein kinase Tec (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TEC 7006; "Homo sapiens (Human)" 1.1483 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 1.11867 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 1.10672 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 1.09341 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 1.0819 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 1.07288 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 1.0673 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P51955 "Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK2 4751; "Homo sapiens (Human)" 1.06322 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9P2K8 "eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK4 440275; "Homo sapiens (Human)" 1.05959 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P54764 "Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA4 2043; "Homo sapiens (Human)" 1.05656 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 1.03025 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 1.02996 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.02624 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 0.985528 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 0.971547 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 0.970347 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9H1R3 "Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK2 85366; "Homo sapiens (Human)" 0.951746 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 0.927158 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 0.906139 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q5VT25 "Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPA 8476; "Homo sapiens (Human)" 0.895115 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 0.876055 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q99640 "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" PKMYT1 9088; "Homo sapiens (Human)" 0.87321 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P41240 "Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" CSK 1445; "Homo sapiens (Human)" 0.867031 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P53671 "LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK2 3985; "Homo sapiens (Human)" 0.834482 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O43781 "Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1) (Regulatory erythroid kinase) (REDK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK3 8444; "Homo sapiens (Human)" 0.829899 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q15569 "Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" TESK1 7016; "Homo sapiens (Human)" 0.828295 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P36897 "TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR1 7046; "Homo sapiens (Human)" 0.822428 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 0.821087 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q09013 "Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) (DMPK) (Myotonic dystrophy protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" DMPK 1760; "Homo sapiens (Human)" 0.81012 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 0.800961 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P27037 "Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2A 92; "Homo sapiens (Human)" 0.768218 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q02779 "Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K10 4294; "Homo sapiens (Human)" 0.721418 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 0.710259 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q86Y07 "Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, VRK subfamily" VRK2 7444; "Homo sapiens (Human)" 0.704354 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 0.683473 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q59H18 "Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" TNNI3K 100526835;51086; "Homo sapiens (Human)" 0.657616 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9UBE8 "Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" NLK 51701; "Homo sapiens (Human)" 0.631802 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P0C1S8 "Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) (Wee1B kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE2 494551; "Homo sapiens (Human)" 0.62094 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9NRP7 "Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK36 27148; "Homo sapiens (Human)" 0.591964 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 0.577304 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 0.559314 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q8NI60 "Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (Coenzyme Q protein 8A) (aarF domain-containing protein kinase 3)" "Protein kinase superfamily, ADCK protein kinase family" COQ8A 56997; "Homo sapiens (Human)" 0.462147 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O43353 "Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK2 8767; "Homo sapiens (Human)" 0.440977 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9Y6R4 "Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K4 4216; "Homo sapiens (Human)" 0.415457 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 0.407899 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P84022 "Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (hMAD-3) (JV15-2) (SMAD family member 3) (SMAD 3) (Smad3) (hSMAD3)" "Dwarfin/SMAD family" SMAD3 4088; "Homo sapiens (Human)" 0.402391 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl Q9NUW8 "Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-)" "Tyrosyl-DNA phosphodiesterase family" TDP1 55775; "Homo sapiens (Human)" 0.272093 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl O00506 "Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK25 10494; "Homo sapiens (Human)" 0.238235 Known 28 CHEMBL5416410 Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1.O OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl P08684 "Cytochrome P450 3A4 (EC 1.14.14.-) (1,8-cineole 2-exo-monooxygenase) (EC 1.14.14.56) (Albendazole monooxygenase (sulfoxide-forming)) (EC 1.14.14.73) (Albendazole sulfoxidase) (CYPIIIA3) (CYPIIIA4) (Cholesterol 25-hydroxylase) (EC 1.14.14.-) (Cytochrome P450 3A3) (Cytochrome P450 HLp) (Cytochrome P450 NF-25) (Cytochrome P450-PCN1) (Nifedipine oxidase) (Quinine 3-monooxygenase) (EC 1.14.14.55) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.14.-)" "Cytochrome P450 family" CYP3A4 1576; "Homo sapiens (Human)" 0.222163 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 3.61977 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P31749 "RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT1 207; "Homo sapiens (Human)" 3.42651 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 3.30777 1 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 3.17997 2 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P17252 "Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCA 5578; "Homo sapiens (Human)" 3.0616 3 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9Y243 "RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT3 10000; "Homo sapiens (Human)" 2.9979 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 2.91043 4 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 2.79235 5 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P24723 "Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCH 5583; "Homo sapiens (Human)" 2.76965 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 2.60699 6 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P11309 "Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM1 5292; "Homo sapiens (Human)" 2.6028 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 2.56764 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q00535 "Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK5 1020; "Homo sapiens (Human)" 2.50686 7 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P31751 "RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC-PK-beta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT2 208; "Homo sapiens (Human)" 2.46109 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 2.4139 8 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 2.38087 9 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 2.34539 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O76039 "Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL5 6792; "Homo sapiens (Human)" 2.29756 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9BWU1 "Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK19 23097; "Homo sapiens (Human)" 2.28209 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 2.24555 10 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 2.13515 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P05771 "Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCB 5579; "Homo sapiens (Human)" 2.10359 11 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 2.09782 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 2.07084 12 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 2.04335 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 2.03671 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 2.02324 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 2.01551 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 2.0024 13 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 1.9813 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 1.97319 14 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q05513 "Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCZ 5590; "Homo sapiens (Human)" 1.89435 15 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q04759 "Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCQ 5588; "Homo sapiens (Human)" 1.88891 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P20794 "Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" MAK 4117; "Homo sapiens (Human)" 1.88461 16 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O75914 "Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK3 5063; "Homo sapiens (Human)" 1.8785 17 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 1.86824 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 1.85354 18 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P09960 "Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)" "Peptidase M1 family" LTA4H 4048; "Homo sapiens (Human)" 1.81502 19 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 1.7895 20 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q13627 "Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1A 1859; "Homo sapiens (Human)" 1.77247 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 1.76423 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 1.76339 21 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q13153 "Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK1 5058; "Homo sapiens (Human)" 1.74126 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 1.72187 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 1.71949 22 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 1.70434 23 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 1.70181 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.70042 24 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 1.68026 25 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q13237 "cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG2 5593; "Homo sapiens (Human)" 1.67851 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 1.67626 26 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9C098 "Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK3 85443; "Homo sapiens (Human)" 1.66993 27 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O00329 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)" "PI3/PI4-kinase family" PIK3CD 5293; "Homo sapiens (Human)" 1.66588 28 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q00526 "Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK3 1018; "Homo sapiens (Human)" 1.6598 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 1.65968 29 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9UQ88 "Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 2) (Cell division protein kinase 11A) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK11A 728642; "Homo sapiens (Human)" 1.65272 30 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 1.65178 31 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 1.64721 32 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.64485 33 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 1.62947 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.62362 34 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q13177 "Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK2 5062; "Homo sapiens (Human)" 1.61878 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9BRS2 "Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK1 83732; "Homo sapiens (Human)" 1.61408 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O14730 "Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK3 8780; "Homo sapiens (Human)" 1.60419 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.60195 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 1.60059 35 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 1.59706 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O14578 "Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" CIT 11113; "Homo sapiens (Human)" 1.59574 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 1.58133 36 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 1.58065 37 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 1.56958 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 1.56879 38 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 1.56347 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O14936 "Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily; MAGUK family" CASK 8573; "Homo sapiens (Human)" 1.55774 39 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 1.55511 40 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 1.55477 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 1.54128 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 1.53336 41 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.51953 42 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 1.51728 43 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P37173 "TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR2 7048; "Homo sapiens (Human)" 1.49785 44 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O94768 "Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17B 9262; "Homo sapiens (Human)" 1.4941 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q99755 "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)" PIP5K1A 8394; "Homo sapiens (Human)" 1.49029 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.47981 45 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 1.46961 46 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.46846 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 1.46398 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 1.46005 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 1.45906 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P21127 "Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK11B 984; "Homo sapiens (Human)" 1.45885 47 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P51817 "cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) (Protein kinase X-linked) (Serine/threonine-protein kinase PRKX) (EC 2.7.11.1) (Protein kinase PKX1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKX 5613; "Homo sapiens (Human)" 1.45851 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9Y463 "Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1B 9149; "Homo sapiens (Human)" 1.44827 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.42759 48 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9P286 "Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK5 57144; "Homo sapiens (Human)" 1.42006 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P03372 "Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)" "Nuclear hormone receptor family, NR3 subfamily" ESR1 2099; "Homo sapiens (Human)" 1.41909 49 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 1.41663 50 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 1.41015 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q86YV6 "Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK4 340156; "Homo sapiens (Human)" 1.39686 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 1.39404 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q16816 "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG1 5260; "Homo sapiens (Human)" 1.38715 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O94921 "Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK14 5218; "Homo sapiens (Human)" 1.38594 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q5VT25 "Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPA 8476; "Homo sapiens (Human)" 1.38139 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P53355 "Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK1 1612; "Homo sapiens (Human)" 1.35835 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 1.34607 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P22694 "cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACB 5567; "Homo sapiens (Human)" 1.34337 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 1.33901 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 1.33331 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.31648 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.31446 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q32MK0 "Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK3 91807; "Homo sapiens (Human)" 1.30213 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q16566 "Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK4 814; "Homo sapiens (Human)" 1.29559 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.2941 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P48729 "Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1 1452; "Homo sapiens (Human)" 1.28037 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 1.27968 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9UIK4 "Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK2 23604; "Homo sapiens (Human)" 1.27476 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 1.26571 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 1.26383 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q02156 "Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCE 5581; "Homo sapiens (Human)" 1.26199 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 1.26048 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 1.25723 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 1.24111 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P49761 "Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK3 1198; "Homo sapiens (Human)" 1.23954 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P78362 "SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK2 6733; "Homo sapiens (Human)" 1.23672 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 1.23532 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.20506 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q92630 "Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK2 8445; "Homo sapiens (Human)" 1.19968 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.19627 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q8TD08 "Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK15 225689; "Homo sapiens (Human)" 1.18062 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q16512 "Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN1 5585; "Homo sapiens (Human)" 1.16063 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P49674 "Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1E 102800317;1454; "Homo sapiens (Human)" 1.13773 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9UBF8 "Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) (NPIK) (PI4K92)" "PI3/PI4-kinase family, Type III PI4K subfamily" PI4KB 5298; "Homo sapiens (Human)" 1.1337 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9UEE5 "Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17A 9263; "Homo sapiens (Human)" 1.13056 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q05655 "Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCD 5580; "Homo sapiens (Human)" 1.12375 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P28482 "Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK1 5594; "Homo sapiens (Human)" 1.12247 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P49137 "MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAP-K2) (MAPKAPK-2) (MK-2) (MK2) (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MAPKAPK2 9261; "Homo sapiens (Human)" 1.11422 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q8N5S9 "Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK1 84254; "Homo sapiens (Human)" 1.09197 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q96SB4 "SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK1 6732; "Homo sapiens (Human)" 1.091 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P78356 "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta)" PIP4K2B 8396; "Homo sapiens (Human)" 1.08601 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q00537 "Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK17 5128; "Homo sapiens (Human)" 1.07112 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O96013 "Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK4 10298; "Homo sapiens (Human)" 1.06987 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.06622 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9NQU5 "Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) (PAK-6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK6 106821730;56924; "Homo sapiens (Human)" 1.06544 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 1.06441 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 1.05366 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 1.05307 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q92772 "Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL2 8999; "Homo sapiens (Human)" 1.05133 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q00536 "Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK16 5127; "Homo sapiens (Human)" 1.0506 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9Y6M4 "Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G3 1456; "Homo sapiens (Human)" 1.01544 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 1.0062 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q13523 "Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" PRPF4B 8899; "Homo sapiens (Human)" 1.00368 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 0.959009 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 0.951977 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 0.94439 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q13976 "cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG1 5592; "Homo sapiens (Human)" 0.941645 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 0.938326 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9UQM7 "Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2A 815; "Homo sapiens (Human)" 0.928918 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q09013 "Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) (DMPK) (Myotonic dystrophy protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" DMPK 1760; "Homo sapiens (Human)" 0.915174 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q8IVW4 "Cyclin-dependent kinase-like 3 (EC 2.7.11.22) (Serine/threonine-protein kinase NKIAMRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL3 51265; "Homo sapiens (Human)" 0.90952 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q13557 "Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2D 817; "Homo sapiens (Human)" 0.89567 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9Y5S2 "Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (CDC42BP-beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPB 9578; "Homo sapiens (Human)" 0.895003 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 0.882721 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 0.882468 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 0.872335 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 0.870114 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 0.867387 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q96BR1 "Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK3 100533105;23678; "Homo sapiens (Human)" 0.866959 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P05129 "Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCG 5582; "Homo sapiens (Human)" 0.860409 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 0.851879 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q07002 "Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK18 5129; "Homo sapiens (Human)" 0.843984 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P78368 "Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G2 1455; "Homo sapiens (Human)" 0.839198 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 0.837345 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q13555 "Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2G 818; "Homo sapiens (Human)" 0.829555 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 0.81091 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 0.810518 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 0.807779 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 0.807334 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 0.80487 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9HCP0 "Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G1 53944; "Homo sapiens (Human)" 0.732084 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9NRM7 "Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS2 26524; "Homo sapiens (Human)" 0.724495 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 0.718157 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q86Y07 "Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, VRK subfamily" VRK2 7444; "Homo sapiens (Human)" 0.702197 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 0.667495 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q8WTQ7 "Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK7 131890; "Homo sapiens (Human)" 0.62334 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q96Q40 "Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK15 65061; "Homo sapiens (Human)" 0.61477 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q9BVS4 "Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK2 55781; "Homo sapiens (Human)" 0.583928 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 0.556296 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 O95835 "Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS1 9113; "Homo sapiens (Human)" 0.537855 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q6DT37 "Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (MRCKG) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPG 55561; "Homo sapiens (Human)" 0.531492 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q13554 "Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2B 816; "Homo sapiens (Human)" 0.44518 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 Q8N752 "Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1L 122011; "Homo sapiens (Human)" 0.428648 Known 29 CHEMBL379218 Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 N[C@@H](Cc1ccccc1)COc1cncc(c1)c1ccc2c(c1)c(C)n[nH]2 P19525 "Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK2 5610; "Homo sapiens (Human)" 0.306054 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 3.50109 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 3.17012 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 2.80558 1 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P49286 "Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)" "G-protein coupled receptor 1 family" MTNR1B 4544; "Homo sapiens (Human)" 2.69798 2 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 2.67832 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O00311 "Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamily" CDC7 8317; "Homo sapiens (Human)" 2.60026 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 2.53351 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 2.45443 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 2.42351 3 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 2.41078 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 2.38577 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 2.36455 4 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q00535 "Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK5 1020; "Homo sapiens (Human)" 2.33268 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 2.33047 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 2.27172 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 2.24242 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P27448 "MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK3 4140; "Homo sapiens (Human)" 2.23591 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 2.22476 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 2.21434 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P48039 "Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)" "G-protein coupled receptor 1 family" MTNR1A 4543; "Homo sapiens (Human)" 2.21211 5 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 2.20124 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 2.15308 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 2.14339 6 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 2.11487 7 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 2.10246 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 2.10172 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 2.0816 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 2.07055 8 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 2.04062 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 2.03798 9 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 2.03767 10 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q96PF2 "Testis-specific serine/threonine-protein kinase 2 (TSK-2) (TSK2) (TSSK-2) (Testis-specific kinase 2) (EC 2.7.11.1) (DiGeorge syndrome protein G) (DGS-G) (Serine/threonine-protein kinase 22B)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK2 23617; "Homo sapiens (Human)" 2.02857 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 2.0249 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 2.01461 11 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 2.00833 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.00133 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 1.99096 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 1.98863 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 1.9573 12 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 1.93471 13 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 1.92025 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 1.91467 14 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.90595 15 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 1.90167 16 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 1.88073 17 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.87951 18 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 1.87132 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 1.86953 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.86118 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 1.83296 19 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 1.80938 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 1.79248 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 1.79161 20 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 1.78699 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 1.75635 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 1.75283 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P28482 "Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK1 5594; "Homo sapiens (Human)" 1.74999 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 1.74797 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q15139 "Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD1 5587; "Homo sapiens (Human)" 1.73116 21 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 1.72971 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 1.72742 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 1.72532 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 1.725 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.725 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.72319 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q13627 "Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1A 1859; "Homo sapiens (Human)" 1.70582 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 1.6917 22 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 1.69167 23 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 1.68199 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 1.66331 24 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 1.66088 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q15759 "Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK11 5600; "Homo sapiens (Human)" 1.66001 25 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 1.65947 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 1.64485 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 1.63937 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 1.63927 26 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 1.63546 27 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P11309 "Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM1 5292; "Homo sapiens (Human)" 1.63256 28 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 1.62543 29 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 1.61746 30 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9BXA7 "Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK1B 83942; "Homo sapiens (Human)" 1.61726 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 1.61653 31 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.61521 32 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 1.59948 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P24385 "G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 oncogene)" "Cyclin family, Cyclin D subfamily" CCND1 595; "Homo sapiens (Human)" 1.58762 33 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9Y243 "RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT3 10000; "Homo sapiens (Human)" 1.57361 34 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.56517 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 1.55922 35 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q8IW41 "MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAP-K5) (MAPKAPK-5) (MK-5) (MK5) (EC 2.7.11.1) (p38-regulated/activated protein kinase) (PRAK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MAPKAPK5 8550; "Homo sapiens (Human)" 1.55609 36 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 1.55498 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 1.55419 37 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 1.54939 38 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 1.54001 39 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 1.53662 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.53618 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 1.53046 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 1.52689 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.52491 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P34913 "Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]" "AB hydrolase superfamily, Epoxide hydrolase family" EPHX2 2053; "Homo sapiens (Human)" 1.52121 40 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.51806 41 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 1.51416 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 1.51206 42 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q04759 "Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCQ 5588; "Homo sapiens (Human)" 1.50957 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.50903 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9UEE5 "Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17A 9263; "Homo sapiens (Human)" 1.50368 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.49835 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 1.4863 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q7KZI7 "Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK2 2011; "Homo sapiens (Human)" 1.47951 43 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.47126 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P31749 "RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT1 207; "Homo sapiens (Human)" 1.46188 44 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 1.4588 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 1.45496 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 1.45494 45 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.45197 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q8TDC3 "Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK1 84446; "Homo sapiens (Human)" 1.45 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P05771 "Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCB 5579; "Homo sapiens (Human)" 1.44783 46 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9H4B4 "Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3) (Proliferation-related kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK3 1263; "Homo sapiens (Human)" 1.44673 47 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P48729 "Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1 1452; "Homo sapiens (Human)" 1.44406 48 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 1.44084 49 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.43201 50 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P51957 "Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK4 6787; "Homo sapiens (Human)" 1.42396 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 1.3997 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9NYL2 "Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K20 51776; "Homo sapiens (Human)" 1.38643 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 1.37942 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 1.3481 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 1.32149 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 1.3197 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 1.31663 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.29816 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 1.26001 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 1.25862 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 1.25537 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 1.24795 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O43781 "Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1) (Regulatory erythroid kinase) (REDK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK3 8444; "Homo sapiens (Human)" 1.24378 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 1.22434 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 1.19965 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P53350 "Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK1 5347; "Homo sapiens (Human)" 1.19738 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 1.17294 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 1.17184 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 1.15095 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 1.11842 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O96013 "Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK4 10298; "Homo sapiens (Human)" 1.09496 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q96SB4 "SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK1 6732; "Homo sapiens (Human)" 1.07397 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q13555 "Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2G 818; "Homo sapiens (Human)" 1.04721 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O15264 "Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK13 5603; "Homo sapiens (Human)" 1.04652 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q13557 "Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2D 817; "Homo sapiens (Human)" 1.04575 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9Y463 "Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1B 9149; "Homo sapiens (Human)" 1.03108 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9HBY8 "Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK2 10110; "Homo sapiens (Human)" 1.025 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.01344 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 1.00598 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P34947 "G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK5 2869; "Homo sapiens (Human)" 0.984568 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 0.964137 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 0.961623 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 0.913891 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P42679 "Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" MATK 4145; "Homo sapiens (Human)" 0.910606 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9UQM7 "Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2A 815; "Homo sapiens (Human)" 0.901977 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 0.874745 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 0.87063 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 0.854632 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P53778 "Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK12 6300; "Homo sapiens (Human)" 0.831721 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 0.802159 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q05655 "Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCD 5580; "Homo sapiens (Human)" 0.796804 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P51955 "Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK2 4751; "Homo sapiens (Human)" 0.792212 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 0.780426 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P05129 "Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCG 5582; "Homo sapiens (Human)" 0.75 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q9HCP0 "Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G1 53944; "Homo sapiens (Human)" 0.735667 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P51817 "cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) (Protein kinase X-linked) (Serine/threonine-protein kinase PRKX) (EC 2.7.11.1) (Protein kinase PKX1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKX 5613; "Homo sapiens (Human)" 0.734143 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 0.717735 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F P78368 "Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G2 1455; "Homo sapiens (Human)" 0.711031 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F O15075 "Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK1 9201; "Homo sapiens (Human)" 0.605999 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q13554 "Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2B 816; "Homo sapiens (Human)" 0.473713 Known 30 CHEMBL1983111 CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CC(=O)NCC(=O)N1C2CCC1c1c2ccc(c1)Nc1ncc(c(n1)NC1CCC1)C(F)(F)F Q5VT25 "Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPA 8476; "Homo sapiens (Human)" 0.425 Known 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 Q92731 "Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)" "Nuclear hormone receptor family, NR3 subfamily" ESR2 2100; "Homo sapiens (Human)" 3.28466 1 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P05067 "Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta A4 protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]" "APP family" APP 351; "Homo sapiens (Human)" 2.84428 2 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 2.79588 3 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P03372 "Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)" "Nuclear hormone receptor family, NR3 subfamily" ESR1 2099; "Homo sapiens (Human)" 2.71633 4 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 2.65103 5 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 2.61107 6 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P43681 "Neuronal acetylcholine receptor subunit alpha-4" "Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Alpha-4/CHRNA4 sub-subfamily" CHRNA4 1137; "Homo sapiens (Human)" 2.60223 7 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P21917 "D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)" "G-protein coupled receptor 1 family" DRD4 1815; "Homo sapiens (Human)" 2.45622 8 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 2.39385 9 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P00742 "Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]" "Peptidase S1 family" F10 2159; "Homo sapiens (Human)" 2.29926 10 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P04278 "Sex hormone-binding globulin (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estradiol-binding globulin) (TeBG) (Testosterone-estrogen-binding globulin)" SHBG 6462; "Homo sapiens (Human)" 2.18278 11 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 2.09522 12 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 Q99705 "Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein coupled receptor 24) (MCH-1R) (MCH1R) (MCHR) (SLC-1) (Somatostatin receptor-like protein)" "G-protein coupled receptor 1 family" MCHR1 2847; "Homo sapiens (Human)" 2.05115 13 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P14625 "Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Tumor rejection antigen 1) (gp96 homolog)" "Heat shock protein 90 family" HSP90B1 7184; "Homo sapiens (Human)" 2.04865 14 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 2.01948 15 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P41595 "5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)" "G-protein coupled receptor 1 family" HTR2B 3357; "Homo sapiens (Human)" 1.95945 16 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 1.95027 17 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 1.94989 18 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P08238 "Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84)" "Heat shock protein 90 family" HSP90AB1 3326; "Homo sapiens (Human)" 1.94058 19 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 1.8709 20 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 1.82064 21 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 1.81887 22 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.81354 23 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 O00141 "Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK1 6446; "Homo sapiens (Human)" 1.76924 24 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 1.74376 25 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P07550 "Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB2 sub-subfamily" ADRB2 154; "Homo sapiens (Human)" 1.70331 26 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 1.67764 27 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 1.65771 28 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.61273 29 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P28335 "5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)" "G-protein coupled receptor 1 family" HTR2C 3358; "Homo sapiens (Human)" 1.57188 30 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P09960 "Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)" "Peptidase M1 family" LTA4H 4048; "Homo sapiens (Human)" 1.57049 31 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 1.54741 32 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 1.52683 33 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 Q13535 "Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1)" "PI3/PI4-kinase family, ATM subfamily" ATR 545; "Homo sapiens (Human)" 1.52335 34 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P36544 "Neuronal acetylcholine receptor subunit alpha-7" "Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Alpha-7/CHRNA7 sub-subfamily" CHRNA7 1139;89832; "Homo sapiens (Human)" 1.51119 35 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.50983 36 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 Q99558 "Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K14 9020; "Homo sapiens (Human)" 1.47688 37 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P05412 "Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)" "BZIP family, Jun subfamily" JUN 3725; "Homo sapiens (Human)" 1.46852 38 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P34972 "Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)" "G-protein coupled receptor 1 family" CNR2 1269; "Homo sapiens (Human)" 1.46369 39 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 1.41542 40 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 1.41221 41 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.39098 42 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.36914 43 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P30542 "Adenosine receptor A1" "G-protein coupled receptor 1 family" ADORA1 134; "Homo sapiens (Human)" 1.35686 44 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 1.35131 45 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 Q13255 "Metabotropic glutamate receptor 1 (mGluR1)" "G-protein coupled receptor 3 family" GRM1 2911; "Homo sapiens (Human)" 1.34862 46 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P29274 "Adenosine receptor A2a" "G-protein coupled receptor 1 family" ADORA2A 135; "Homo sapiens (Human)" 1.3423 47 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P31751 "RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC-PK-beta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT2 208; "Homo sapiens (Human)" 1.28917 48 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P00374 "Dihydrofolate reductase (EC 1.5.1.3)" "Dihydrofolate reductase family" DHFR 1719; "Homo sapiens (Human)" 1.28911 49 31 CHEMBL1986943 OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 OC1CCC(CC1)Nc1nc(Cl)cc(n1)c1c[nH]c2c1cccn2 P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 1.2889 50 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 3.10935 1 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 2.96332 2 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 2.94966 3 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 2.90192 4 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P05771 "Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCB 5579; "Homo sapiens (Human)" 2.7488 5 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q16584 "Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K11 4296; "Homo sapiens (Human)" 2.69143 6 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 2.68415 7 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9P0L2 "Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK1 4139; "Homo sapiens (Human)" 2.57926 8 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 2.57773 9 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 2.5735 10 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q02156 "Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCE 5581; "Homo sapiens (Human)" 2.36032 11 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 2.32213 12 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P41597 "C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (Monocyte chemoattractant protein 1 receptor) (MCP-1-R) (CD antigen CD192)" "G-protein coupled receptor 1 family" CCR2 729230; "Homo sapiens (Human)" 2.28045 13 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13490 "Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2)" "IAP family" BIRC2 329; "Homo sapiens (Human)" 2.27583 14 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q02779 "Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K10 4294; "Homo sapiens (Human)" 2.26427 15 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q05655 "Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCD 5580; "Homo sapiens (Human)" 2.16692 16 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P34972 "Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)" "G-protein coupled receptor 1 family" CNR2 1269; "Homo sapiens (Human)" 2.13208 17 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P05129 "Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCG 5582; "Homo sapiens (Human)" 2.08907 18 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P09874 "Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-)" PARP1 142; "Homo sapiens (Human)" 1.99866 19 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 1.96068 20 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 1.95137 21 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P17252 "Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCA 5578; "Homo sapiens (Human)" 1.90972 22 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P80370 "Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen 1 (FA1)]" DLK1 8788; "Homo sapiens (Human)" 1.79343 23 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q15910 "Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.43) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)" "Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, EZ subfamily" EZH2 2146; "Homo sapiens (Human)" 1.73584 24 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.72288 25 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13489 "Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)" "IAP family" BIRC3 330; "Homo sapiens (Human)" 1.72065 26 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 1.6663 27 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P98170 "E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP-like protein) (ILP) (hILP) (Inhibitor of apoptosis protein 3) (IAP-3) (hIAP-3) (hIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP)" "IAP family" XIAP 331; "Homo sapiens (Human)" 1.59029 28 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.57742 29 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P00734 "Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain]" "Peptidase S1 family" F2 2147; "Homo sapiens (Human)" 1.56567 30 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.55537 31 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P11309 "Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM1 5292; "Homo sapiens (Human)" 1.55037 32 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.46272 33 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 1.44931 34 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P50406 "5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)" "G-protein coupled receptor 1 family" HTR6 3362; "Homo sapiens (Human)" 1.38019 35 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P0DMS8 "Adenosine receptor A3" "G-protein coupled receptor 1 family" ADORA3 140; "Homo sapiens (Human)" 1.35228 36 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P41143 "Delta-type opioid receptor (D-OR-1) (DOR-1)" "G-protein coupled receptor 1 family" OPRD1 4985; "Homo sapiens (Human)" 1.29809 37 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.29493 38 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 1.29282 39 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P78527 "DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)" "PI3/PI4-kinase family" PRKDC 5591; "Homo sapiens (Human)" 1.26565 40 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q9Y5Y9 "Sodium channel protein type 10 subunit alpha (Peripheral nerve sodium channel 3) (PN3) (hPN3) (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8)" "Sodium channel (TC 1.A.1.10) family, Nav1.8/SCN10A subfamily" SCN10A 6336; "Homo sapiens (Human)" 1.24731 41 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 1.22001 42 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P49286 "Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)" "G-protein coupled receptor 1 family" MTNR1B 4544; "Homo sapiens (Human)" 1.21049 43 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P29371 "Neuromedin-K receptor (NKR) (NK-3 receptor) (NK-3R) (Neurokinin B receptor) (Tachykinin receptor 3)" "G-protein coupled receptor 1 family" TACR3 6870; "Homo sapiens (Human)" 1.20405 44 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 1.1869 45 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q8NER1 "Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)" "Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamily" TRPV1 7442; "Homo sapiens (Human)" 1.17201 46 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P30291 "Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE1 7465; "Homo sapiens (Human)" 1.14931 47 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q13639 "5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4)" "G-protein coupled receptor 1 family" HTR4 3360; "Homo sapiens (Human)" 1.1357 48 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O P11229 "Muscarinic acetylcholine receptor M1" "G-protein coupled receptor 1 family, Muscarinic acetylcholine receptor subfamily, CHRM1 sub-subfamily" CHRM1 1128; "Homo sapiens (Human)" 1.09802 49 32 CHEMBL1980995 CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CNC1CC2OC(C1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O Q96P09 "Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis)" "IAP family" BIRC8 112401; "Homo sapiens (Human)" 1.09247 50 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P24864 "G1/S-specific cyclin-E1" "Cyclin family, Cyclin E subfamily" CCNE1 898; "Homo sapiens (Human)" 3.61092 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P24385 "G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 oncogene)" "Cyclin family, Cyclin D subfamily" CCND1 595; "Homo sapiens (Human)" 3.47566 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O60563 "Cyclin-T1 (CycT1) (Cyclin-T)" "Cyclin family, Cyclin C subfamily" CCNT1 904; "Homo sapiens (Human)" 2.84252 1 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 2.76716 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 2.74601 2 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 2.62777 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 2.53577 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 2.51373 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 2.50939 3 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 2.5052 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 2.45599 4 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 2.43086 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 2.42557 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 2.40821 5 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 2.40115 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 2.38828 6 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 2.36476 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 2.36239 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 2.30521 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 2.29682 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 2.26331 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O00311 "Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamily" CDC7 8317; "Homo sapiens (Human)" 2.2561 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 2.22502 7 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 2.22145 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P30291 "Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily" WEE1 7465; "Homo sapiens (Human)" 2.18982 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 2.13131 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 2.11885 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 2.10418 8 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.98812 9 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 1.98386 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.97316 10 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 1.96742 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 1.92761 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 1.90301 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P27448 "MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK3 4140; "Homo sapiens (Human)" 1.88592 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P14635 "G2/mitotic-specific cyclin-B1" "Cyclin family, Cyclin AB subfamily" CCNB1 891; "Homo sapiens (Human)" 1.88434 11 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 1.806 12 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P30281 "G1/S-specific cyclin-D3" "Cyclin family, Cyclin D subfamily" CCND3 896; "Homo sapiens (Human)" 1.80475 13 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 1.80245 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 1.79425 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.78111 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 1.77814 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 1.77231 14 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q00535 "Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK5 1020; "Homo sapiens (Human)" 1.7693 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 1.75376 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.7394 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 1.72781 15 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9Y463 "Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1B 9149; "Homo sapiens (Human)" 1.71995 16 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 1.70647 17 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 1.69897 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 1.68092 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P31749 "RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT1 207; "Homo sapiens (Human)" 1.67914 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 1.675 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q15139 "Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD1 5587; "Homo sapiens (Human)" 1.66927 18 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 1.65845 19 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P53350 "Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK1 5347; "Homo sapiens (Human)" 1.64877 20 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 1.62953 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 1.62581 21 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 1.6052 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 1.59731 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q13627 "Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1A 1859; "Homo sapiens (Human)" 1.59677 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.59383 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P20248 "Cyclin-A2 (Cyclin-A) (Cyclin A)" "Cyclin family, Cyclin AB subfamily" CCNA2 890; "Homo sapiens (Human)" 1.58167 22 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 1.57911 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.57463 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 1.55562 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 1.55175 23 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q13555 "Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2G 818; "Homo sapiens (Human)" 1.54189 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P29274 "Adenosine receptor A2a" "G-protein coupled receptor 1 family" ADORA2A 135; "Homo sapiens (Human)" 1.53847 24 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 1.52845 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 1.52615 25 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 1.51559 26 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 1.50959 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 1.50936 27 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 1.50495 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 1.5 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q13557 "Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2D 817; "Homo sapiens (Human)" 1.49986 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 1.49872 28 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q8TDC3 "Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" BRSK1 84446; "Homo sapiens (Human)" 1.49213 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 1.49163 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.49071 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9Y243 "RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT3 10000; "Homo sapiens (Human)" 1.48416 29 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q8IW41 "MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAP-K5) (MAPKAPK-5) (MK-5) (MK5) (EC 2.7.11.1) (p38-regulated/activated protein kinase) (PRAK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MAPKAPK5 8550; "Homo sapiens (Human)" 1.48241 30 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P49674 "Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1E 102800317;1454; "Homo sapiens (Human)" 1.47326 31 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P42336 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)" "PI3/PI4-kinase family" PIK3CA 5290; "Homo sapiens (Human)" 1.47282 32 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 1.46944 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 1.46914 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.46907 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 1.45456 33 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 1.44417 34 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 1.43023 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 1.42863 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 1.42805 35 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.425 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P05067 "Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta A4 protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]" "APP family" APP 351; "Homo sapiens (Human)" 1.42244 36 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 1.42126 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 1.40967 37 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 1.40906 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 1.40274 38 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 1.37517 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 1.37305 39 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 1.34626 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q00534 "Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK6 1021; "Homo sapiens (Human)" 1.3457 40 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 1.3447 41 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.34191 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.33207 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 1.3314 42 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.32431 43 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 1.32217 44 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.31705 45 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 1.31051 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 1.30957 46 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 1.30385 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 1.30319 47 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 1.29574 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 1.29247 48 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9NYL2 "Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K20 51776; "Homo sapiens (Human)" 1.28643 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 1.27635 49 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 1.27288 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 1.26413 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 1.24566 50 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.23098 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P51957 "Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK4 6787; "Homo sapiens (Human)" 1.22397 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 1.22182 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 1.15 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 1.12943 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9UEE5 "Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17A 9263; "Homo sapiens (Human)" 1.08224 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P51955 "Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)" "Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily" NEK2 4751; "Homo sapiens (Human)" 1.05 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.025 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P48729 "Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1 1452; "Homo sapiens (Human)" 0.9909 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 0.957287 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9HBY8 "Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" SGK2 10110; "Homo sapiens (Human)" 0.95 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 0.932292 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 0.876601 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 0.853389 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 0.83991 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9UQM7 "Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2A 815; "Homo sapiens (Human)" 0.834819 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 0.791809 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9HCP0 "Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G1 53944; "Homo sapiens (Human)" 0.775515 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P78368 "Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G2 1455; "Homo sapiens (Human)" 0.774999 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 0.733193 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C P53778 "Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK12 6300; "Homo sapiens (Human)" 0.70672 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 0.697003 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C O96013 "Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK4 10298; "Homo sapiens (Human)" 0.692024 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 0.675 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 0.48072 Known 33 CHEMBL482967 Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 Nc1nc(c(s1)c1ccnc(n1)Nc1ccc(cc1)N1CCOCC1)C Q13554 "Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2B 816; "Homo sapiens (Human)" 0.441873 Known 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P83916 "Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)" CBX1 10951; "Homo sapiens (Human)" 3.22185 1 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P49286 "Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)" "G-protein coupled receptor 1 family" MTNR1B 4544; "Homo sapiens (Human)" 3.09803 2 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 Q92731 "Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)" "Nuclear hormone receptor family, NR3 subfamily" ESR2 2100; "Homo sapiens (Human)" 2.79972 3 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 2.79853 4 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 Q13255 "Metabotropic glutamate receptor 1 (mGluR1)" "G-protein coupled receptor 3 family" GRM1 2911; "Homo sapiens (Human)" 2.52055 5 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 2.48811 6 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P03372 "Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)" "Nuclear hormone receptor family, NR3 subfamily" ESR1 2099; "Homo sapiens (Human)" 2.39439 7 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 Q9BV23 "Monoacylglycerol lipase ABHD6 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 6)" "AB hydrolase superfamily" ABHD6 57406; "Homo sapiens (Human)" 2.33447 8 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P28222 "5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (S12) (Serotonin 1D beta receptor) (5-HT-1D-beta) (Serotonin receptor 1B)" "G-protein coupled receptor 1 family" HTR1B 3351; "Homo sapiens (Human)" 2.19619 9 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 Q8NER1 "Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)" "Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamily" TRPV1 7442; "Homo sapiens (Human)" 2.19594 10 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 Q8NCG7 "Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-) (KCCR13L)" "AB hydrolase superfamily, Lipase family" DAGLB 221955; "Homo sapiens (Human)" 2.11004 11 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P00742 "Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]" "Peptidase S1 family" F10 2159; "Homo sapiens (Human)" 2.10917 12 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P28221 "5-hydroxytryptamine receptor 1D (5-HT-1D) (5-HT1D) (Serotonin 1D alpha receptor) (5-HT-1D-alpha) (Serotonin receptor 1D)" "G-protein coupled receptor 1 family" HTR1D 3352; "Homo sapiens (Human)" 2.08004 13 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P08908 "5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)" "G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamily" HTR1A 3350; "Homo sapiens (Human)" 2.047 14 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P15538 "Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase) (EC 1.14.15.4)" "Cytochrome P450 family" CYP11B1 1584; "Homo sapiens (Human)" 1.96509 15 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P34972 "Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)" "G-protein coupled receptor 1 family" CNR2 1269; "Homo sapiens (Human)" 1.9546 16 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P05067 "Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta A4 protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]" "APP family" APP 351; "Homo sapiens (Human)" 1.91601 17 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P03952 "Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) (PKK) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain]" "Peptidase S1 family, Plasma kallikrein subfamily" KLKB1 3818; "Homo sapiens (Human)" 1.883 18 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P09874 "Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-)" PARP1 142; "Homo sapiens (Human)" 1.8631 19 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 1.81761 20 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 1.81172 21 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 1.81012 22 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P27338 "Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B)" "Flavin monoamine oxidase family" MAOB 4129; "Homo sapiens (Human)" 1.78184 23 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.68456 24 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P09917 "Arachidonate 5-lipoxygenase (5-LO) (5-lipoxygenase) (EC 1.13.11.34)" "Lipoxygenase family" ALOX5 240; "Homo sapiens (Human)" 1.67616 25 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P11511 "Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase)" "Cytochrome P450 family" CYP19A1 1588; "Homo sapiens (Human)" 1.66242 26 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 Q9Y4D2 "Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator)" "AB hydrolase superfamily, Lipase family" DAGLA 747; "Homo sapiens (Human)" 1.63798 27 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P35372 "Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)" "G-protein coupled receptor 1 family" OPRM1 4988; "Homo sapiens (Human)" 1.6336 28 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.62019 29 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 Q99705 "Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein coupled receptor 24) (MCH-1R) (MCH1R) (MCHR) (SLC-1) (Somatostatin receptor-like protein)" "G-protein coupled receptor 1 family" MCHR1 2847; "Homo sapiens (Human)" 1.61011 30 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P30542 "Adenosine receptor A1" "G-protein coupled receptor 1 family" ADORA1 134; "Homo sapiens (Human)" 1.60912 31 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P14061 "Estradiol 17-beta-dehydrogenase 1 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 1) (17-beta-HSD 1) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Placental 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 28C member 1)" "Short-chain dehydrogenases/reductases (SDR) family" HSD17B1 3292; "Homo sapiens (Human)" 1.59683 32 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P00918 "Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)" "Alpha-carbonic anhydrase family" CA2 760; "Homo sapiens (Human)" 1.56455 33 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P0DMS8 "Adenosine receptor A3" "G-protein coupled receptor 1 family" ADORA3 140; "Homo sapiens (Human)" 1.56214 34 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P48039 "Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)" "G-protein coupled receptor 1 family" MTNR1A 4543; "Homo sapiens (Human)" 1.5374 35 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P27815 "cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.53) (DPDE2) (PDE46)" "Cyclic nucleotide phosphodiesterase family, PDE4 subfamily" PDE4A 5141; "Homo sapiens (Human)" 1.50972 36 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.47013 37 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 Q13547 "Histone deacetylase 1 (HD1) (EC 3.5.1.98)" "Histone deacetylase family, HD type 1 subfamily" HDAC1 3065; "Homo sapiens (Human)" 1.46189 38 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 O43570 "Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)" "Alpha-carbonic anhydrase family" CA12 771; "Homo sapiens (Human)" 1.33384 39 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P25101 "Endothelin-1 receptor (Endothelin receptor type A) (ET-A) (ETA-R) (hET-AR)" "G-protein coupled receptor 1 family, Endothelin receptor subfamily, EDNRA sub-subfamily" EDNRA 1909; "Homo sapiens (Human)" 1.33292 40 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 1.32671 41 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P78527 "DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)" "PI3/PI4-kinase family" PRKDC 5591; "Homo sapiens (Human)" 1.3249 42 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 1.30418 43 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 1.30124 44 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P00915 "Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase B) (CAB) (Carbonic anhydrase I) (CA-I)" "Alpha-carbonic anhydrase family" CA1 759; "Homo sapiens (Human)" 1.29028 45 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 1.26517 46 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P35348 "Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1A sub-subfamily" ADRA1A 148; "Homo sapiens (Human)" 1.26209 47 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P50406 "5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)" "G-protein coupled receptor 1 family" HTR6 3362; "Homo sapiens (Human)" 1.2384 48 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 P29274 "Adenosine receptor A2a" "G-protein coupled receptor 1 family" ADORA2A 135; "Homo sapiens (Human)" 1.23117 49 34 CHEMBL1991078 COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC COc1cc(ccc1OC)C(=O)Nc1n[nH]c2c1cc(cc2)c1nnn(c1)Cc1ccccc1 Q96RI0 "Proteinase-activated receptor 4 (PAR-4) (Coagulation factor II receptor-like 3) (Thrombin receptor-like 3)" "G-protein coupled receptor 1 family" F2RL3 9002; "Homo sapiens (Human)" 1.22939 50 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P00374 "Dihydrofolate reductase (EC 1.5.1.3)" "Dihydrofolate reductase family" DHFR 1719; "Homo sapiens (Human)" 3.4275 1 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 2.92305 2 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 Q6UVM3 "Potassium channel subfamily T member 2 (Sequence like an intermediate conductance potassium channel subunit) (Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1)" "Potassium channel family, Calcium-activated (TC 1.A.1.3) subfamily, KCa4.2/KCNT2 sub-subfamily" KCNT2 343450; "Homo sapiens (Human)" 2.73444 3 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 Q8NER1 "Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)" "Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamily" TRPV1 7442; "Homo sapiens (Human)" 2.37992 4 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 2.35145 5 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 Q16602 "Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor)" "G-protein coupled receptor 2 family" CALCRL 10203; "Homo sapiens (Human)" 2.31731 6 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 2.28814 7 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P12104 "Fatty acid-binding protein, intestinal (Fatty acid-binding protein 2) (Intestinal-type fatty acid-binding protein) (I-FABP)" "Calycin superfamily, Fatty-acid binding protein (FABP) family" FABP2 2169; "Homo sapiens (Human)" 2.27881 8 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 2.23811 9 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 O43570 "Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)" "Alpha-carbonic anhydrase family" CA12 771; "Homo sapiens (Human)" 2.22263 10 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.98723 11 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 1.84319 12 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P09917 "Arachidonate 5-lipoxygenase (5-LO) (5-lipoxygenase) (EC 1.13.11.34)" "Lipoxygenase family" ALOX5 240; "Homo sapiens (Human)" 1.80728 13 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P27338 "Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B)" "Flavin monoamine oxidase family" MAOB 4129; "Homo sapiens (Human)" 1.74023 14 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 1.72625 15 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.70017 16 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 1.68303 17 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P11137 "Microtubule-associated protein 2 (MAP-2)" MAP2 4133; "Homo sapiens (Human)" 1.66026 18 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P42330 "Aldo-keto reductase family 1 member C3 (EC 1.-.-.-) (17-beta-hydroxysteroid dehydrogenase type 5) (17-beta-HSD 5) (3-alpha-HSD type II, brain) (3-alpha-hydroxysteroid dehydrogenase type 2) (3-alpha-HSD type 2) (EC 1.1.1.357) (Chlordecone reductase homolog HAKRb) (Dihydrodiol dehydrogenase 3) (DD-3) (DD3) (Dihydrodiol dehydrogenase type I) (HA1753) (Indanol dehydrogenase) (EC 1.1.1.112) (Prostaglandin F synthase) (PGFS) (EC 1.1.1.188) (Testosterone 17-beta-dehydrogenase 5) (EC 1.1.1.239) (EC 1.1.1.64) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20)" "Aldo/keto reductase family" AKR1C3 8644; "Homo sapiens (Human)" 1.65552 19 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 1.64309 20 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 Q14833 "Metabotropic glutamate receptor 4 (mGluR4)" "G-protein coupled receptor 3 family" GRM4 2914; "Homo sapiens (Human)" 1.59749 21 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 1.5127 22 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 Q9H244 "P2Y purinoceptor 12 (P2Y12) (ADP-glucose receptor) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) (P2Y12 platelet ADP receptor) (P2Y(ADP)) (SP1999)" "G-protein coupled receptor 1 family" P2RY12 64805; "Homo sapiens (Human)" 1.49409 23 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 1.45148 24 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.43589 25 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 1.42396 26 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.41134 27 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P31213 "3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.1.22) (5 alpha-SR2) (SR type 2) (Steroid 5-alpha-reductase 2) (S5AR 2) (Type II 5-alpha reductase)" "Steroid 5-alpha reductase family" SRD5A2 6716; "Homo sapiens (Human)" 1.4068 28 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.37178 29 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 Q15722 "Leukotriene B4 receptor 1 (LTB4-R 1) (LTB4-R1) (Chemoattractant receptor-like 1) (G-protein coupled receptor 16) (P2Y purinoceptor 7) (P2Y7)" "G-protein coupled receptor 1 family" LTB4R 1241; "Homo sapiens (Human)" 1.36433 30 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P68400 "Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A1 1457; "Homo sapiens (Human)" 1.36295 31 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P00915 "Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase B) (CAB) (Carbonic anhydrase I) (CA-I)" "Alpha-carbonic anhydrase family" CA1 759; "Homo sapiens (Human)" 1.361 32 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P50579 "Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Initiation factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2) (Peptidase M)" "Peptidase M24A family, Methionine aminopeptidase eukaryotic type 2 subfamily" METAP2 10988; "Homo sapiens (Human)" 1.33827 33 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P00918 "Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)" "Alpha-carbonic anhydrase family" CA2 760; "Homo sapiens (Human)" 1.33533 34 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 Q04828 "Aldo-keto reductase family 1 member C1 (EC 1.1.1.-) (20-alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (EC 1.1.1.149) (Chlordecone reductase homolog HAKRC) (Dihydrodiol dehydrogenase 1/2) (DD1/DD2) (High-affinity hepatic bile acid-binding protein) (HBAB) (Indanol dehydrogenase) (EC 1.1.1.112) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20)" "Aldo/keto reductase family" AKR1C1 1645; "Homo sapiens (Human)" 1.32047 35 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P13631 "Retinoic acid receptor gamma (RAR-gamma) (Nuclear receptor subfamily 1 group B member 3)" "Nuclear hormone receptor family, NR1 subfamily" RARG 5916; "Homo sapiens (Human)" 1.29068 36 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P10826 "Retinoic acid receptor beta (RAR-beta) (HBV-activated protein) (Nuclear receptor subfamily 1 group B member 2) (RAR-epsilon)" "Nuclear hormone receptor family, NR1 subfamily" RARB 5915; "Homo sapiens (Human)" 1.2754 37 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 1.23052 38 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 Q04609 "Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Cell growth-inhibiting gene 27 protein) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen) (PSM) (PSMA) (Pteroylpoly-gamma-glutamate carboxypeptidase)" "Peptidase M28 family, M28B subfamily" FOLH1 2346; "Homo sapiens (Human)" 1.22378 39 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.1982 40 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.19757 41 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P30556 "Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1)" "G-protein coupled receptor 1 family" AGTR1 185; "Homo sapiens (Human)" 1.18236 42 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.17163 43 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P31645 "Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)" "Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamily" SLC6A4 6532; "Homo sapiens (Human)" 1.16672 44 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 Q16790 "Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)" "Alpha-carbonic anhydrase family" CA9 768; "Homo sapiens (Human)" 1.16614 45 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 1.15458 46 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P11511 "Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase)" "Cytochrome P450 family" CYP19A1 1588; "Homo sapiens (Human)" 1.12523 47 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P12268 "Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2) (IMPD 2) (IMPDH 2) (EC 1.1.1.205) (IMPDH-II)" "IMPDH/GMPR family" IMPDH2 3615; "Homo sapiens (Human)" 1.12221 48 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 1.10908 49 35 CHEMBL244378 O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 OC(=O)c1ccccc1Nc1ccnc(n1)Nc1ccc2c(c1)[nH]nc2 O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 1.09746 50 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 3.83946 1 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P50406 "5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)" "G-protein coupled receptor 1 family" HTR6 3362; "Homo sapiens (Human)" 3.70055 2 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 3.47084 3 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P00374 "Dihydrofolate reductase (EC 1.5.1.3)" "Dihydrofolate reductase family" DHFR 1719; "Homo sapiens (Human)" 3.19414 4 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P08908 "5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)" "G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamily" HTR1A 3350; "Homo sapiens (Human)" 2.99355 5 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 2.892 6 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P34913 "Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]" "AB hydrolase superfamily, Epoxide hydrolase family" EPHX2 2053; "Homo sapiens (Human)" 2.83158 7 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 2.7983 8 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P43115 "Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor)" "G-protein coupled receptor 1 family" PTGER3 5733; "Homo sapiens (Human)" 2.64351 9 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P35367 "Histamine H1 receptor (H1R) (HH1R)" "G-protein coupled receptor 1 family" HRH1 3269; "Homo sapiens (Human)" 2.60226 10 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 2.58463 11 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 2.58001 12 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 2.51923 13 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P41145 "Kappa-type opioid receptor (K-OR-1) (KOR-1)" "G-protein coupled receptor 1 family" OPRK1 4986; "Homo sapiens (Human)" 2.50254 14 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 2.48203 15 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P41595 "5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)" "G-protein coupled receptor 1 family" HTR2B 3357; "Homo sapiens (Human)" 2.29191 16 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 2.18369 17 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P21917 "D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)" "G-protein coupled receptor 1 family" DRD4 1815; "Homo sapiens (Human)" 2.12988 18 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 2.08396 19 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 2.0408 20 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 1.99752 21 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 1.98621 22 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.96588 23 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.95585 24 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P28335 "5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)" "G-protein coupled receptor 1 family" HTR2C 3358; "Homo sapiens (Human)" 1.91275 25 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 1.89545 26 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 1.83474 27 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P25100 "Alpha-1D adrenergic receptor (Alpha-1A adrenergic receptor) (Alpha-1D adrenoreceptor) (Alpha-1D adrenoceptor) (Alpha-adrenergic receptor 1a)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA1D sub-subfamily" ADRA1D 146; "Homo sapiens (Human)" 1.82054 28 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P10275 "Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)" "Nuclear hormone receptor family, NR3 subfamily" AR 367; "Homo sapiens (Human)" 1.81843 29 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F Q8N884 "Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1)" "Mab-21 family" CGAS 115004; "Homo sapiens (Human)" 1.7922 30 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F Q99705 "Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein coupled receptor 24) (MCH-1R) (MCH1R) (MCHR) (SLC-1) (Somatostatin receptor-like protein)" "G-protein coupled receptor 1 family" MCHR1 2847; "Homo sapiens (Human)" 1.78553 31 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 1.72017 32 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 1.7067 33 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 1.69515 34 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P34981 "Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberin receptor)" "G-protein coupled receptor 1 family" TRHR 7201; "Homo sapiens (Human)" 1.64882 35 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.64449 36 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 1.60177 37 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 1.59735 38 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 1.59331 39 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F O43570 "Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)" "Alpha-carbonic anhydrase family" CA12 771; "Homo sapiens (Human)" 1.58009 40 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 1.54963 41 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 1.54927 42 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P29274 "Adenosine receptor A2a" "G-protein coupled receptor 1 family" ADORA2A 135; "Homo sapiens (Human)" 1.51762 43 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P28221 "5-hydroxytryptamine receptor 1D (5-HT-1D) (5-HT1D) (Serotonin 1D alpha receptor) (5-HT-1D-alpha) (Serotonin receptor 1D)" "G-protein coupled receptor 1 family" HTR1D 3352; "Homo sapiens (Human)" 1.49577 44 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P14324 "Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase)" "FPP/GGPP synthase family" FDPS 2224; "Homo sapiens (Human)" 1.49197 45 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 1.48681 46 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F Q13547 "Histone deacetylase 1 (HD1) (EC 3.5.1.98)" "Histone deacetylase family, HD type 1 subfamily" HDAC1 3065; "Homo sapiens (Human)" 1.47436 47 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F Q99720 "Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding protein) (SR-BP) (Sigma 1-type opioid receptor) (SIG-1R) (Sigma1-receptor) (Sigma1R) (hSigmaR1)" "ERG2 family" SIGMAR1 10280; "Homo sapiens (Human)" 1.45924 48 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P27487 "Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)]" "Peptidase S9B family, DPPIV subfamily" DPP4 1803; "Homo sapiens (Human)" 1.4592 49 36 CHEMBL1967878 Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CN1CCN(CC1)c1ccc(cc1C)Nc1ncc(c(n1)NC1C2C=CC(C1C(=O)N)C2)F P35408 "Prostaglandin E2 receptor EP4 subtype (PGE receptor EP4 subtype) (PGE2 receptor EP4 subtype) (Prostanoid EP4 receptor)" "G-protein coupled receptor 1 family" PTGER4 5734; "Homo sapiens (Human)" 1.44641 50 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P05067 "Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta A4 protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]" "APP family" APP 351; "Homo sapiens (Human)" 2.72954 1 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC Q8TDV5 "Glucose-dependent insulinotropic receptor (G-protein coupled receptor 119)" "G-protein coupled receptor 1 family" GPR119 139760; "Homo sapiens (Human)" 2.6641 2 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 2.4061 3 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 2.37527 4 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC O43570 "Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)" "Alpha-carbonic anhydrase family" CA12 771; "Homo sapiens (Human)" 2.34059 5 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 2.33368 6 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 2.30464 7 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P35372 "Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)" "G-protein coupled receptor 1 family" OPRM1 4988; "Homo sapiens (Human)" 2.29778 8 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P27815 "cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.53) (DPDE2) (PDE46)" "Cyclic nucleotide phosphodiesterase family, PDE4 subfamily" PDE4A 5141; "Homo sapiens (Human)" 2.28878 9 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 2.23963 10 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC Q13936 "Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)" "Calcium channel alpha-1 subunit (TC 1.A.1.11) family, CACNA1C subfamily" CACNA1C 775; "Homo sapiens (Human)" 2.18032 11 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 2.14176 12 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 2.0494 13 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC Q16790 "Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)" "Alpha-carbonic anhydrase family" CA9 768; "Homo sapiens (Human)" 2.03117 14 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 1.91187 15 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.87118 16 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P21964 "Catechol O-methyltransferase (EC 2.1.1.6)" "Class I-like SAM-binding methyltransferase superfamily, Cation-dependent O-methyltransferase family" COMT 1312; "Homo sapiens (Human)" 1.87096 17 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 1.86017 18 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 1.85068 19 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P49286 "Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)" "G-protein coupled receptor 1 family" MTNR1B 4544; "Homo sapiens (Human)" 1.8388 20 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P21917 "D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)" "G-protein coupled receptor 1 family" DRD4 1815; "Homo sapiens (Human)" 1.83215 21 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.79654 22 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P00374 "Dihydrofolate reductase (EC 1.5.1.3)" "Dihydrofolate reductase family" DHFR 1719; "Homo sapiens (Human)" 1.79237 23 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 1.78657 24 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 1.76925 25 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P10275 "Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)" "Nuclear hormone receptor family, NR3 subfamily" AR 367; "Homo sapiens (Human)" 1.72299 26 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P50406 "5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)" "G-protein coupled receptor 1 family" HTR6 3362; "Homo sapiens (Human)" 1.63004 27 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 1.62744 28 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.62714 29 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P10145 "Interleukin-8 (IL-8) (C-X-C motif chemokine 8) (Chemokine (C-X-C motif) ligand 8) (Emoctakin) (Granulocyte chemotactic protein 1) (GCP-1) (Monocyte-derived neutrophil chemotactic factor) (MDNCF) (Monocyte-derived neutrophil-activating peptide) (MONAP) (Neutrophil-activating protein 1) (NAP-1) (Protein 3-10C) (T-cell chemotactic factor) [Cleaved into: MDNCF-a (GCP/IL-8 protein IV) (IL8/NAP1 form I); Interleukin-8 ((Ala-IL-8)77) (GCP/IL-8 protein II) (IL-8(1-77)) (IL8/NAP1 form II) (MDNCF-b); IL-8(5-77); IL-8(6-77) ((Ser-IL-8)72) (GCP/IL-8 protein I) (IL8/NAP1 form III) (Lymphocyte-derived neutrophil-activating factor) (LYNAP) (MDNCF-c) (Neutrophil-activating factor) (NAF); IL-8(7-77) (GCP/IL-8 protein V) (IL8/NAP1 form IV); IL-8(8-77) (GCP/IL-8 protein VI) (IL8/NAP1 form V); IL-8(9-77) (GCP/IL-8 protein III) (IL8/NAP1 form VI)]" "Intercrine alpha (chemokine CxC) family" CXCL8 3576; "Homo sapiens (Human)" 1.62463 30 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 1.6156 31 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC Q13639 "5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4)" "G-protein coupled receptor 1 family" HTR4 3360; "Homo sapiens (Human)" 1.59969 32 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P08908 "5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)" "G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamily" HTR1A 3350; "Homo sapiens (Human)" 1.59655 33 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P41145 "Kappa-type opioid receptor (K-OR-1) (KOR-1)" "G-protein coupled receptor 1 family" OPRK1 4986; "Homo sapiens (Human)" 1.58539 34 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 1.54419 35 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC Q99808 "Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1)" "SLC29A/ENT transporter (TC 2.A.57) family" SLC29A1 2030; "Homo sapiens (Human)" 1.54108 36 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P41143 "Delta-type opioid receptor (D-OR-1) (DOR-1)" "G-protein coupled receptor 1 family" OPRD1 4985; "Homo sapiens (Human)" 1.53414 37 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P46098 "5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)" "Ligand-gated ion channel (TC 1.A.9) family, 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily, HTR3A sub-subfamily" HTR3A 3359; "Homo sapiens (Human)" 1.5241 38 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P41595 "5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)" "G-protein coupled receptor 1 family" HTR2B 3357; "Homo sapiens (Human)" 1.50835 39 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 1.50324 40 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P51679 "C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) (K5-5) (CD antigen CD194)" "G-protein coupled receptor 1 family" CCR4 1233; "Homo sapiens (Human)" 1.49683 41 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.47919 42 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 1.47114 43 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC Q07343 "cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.53) (DPDE4) (PDE32)" "Cyclic nucleotide phosphodiesterase family, PDE4 subfamily" PDE4B 5142; "Homo sapiens (Human)" 1.44715 44 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P09874 "Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-)" PARP1 142; "Homo sapiens (Human)" 1.41912 45 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 1.40162 46 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.39292 47 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 1.39066 48 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P83916 "Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)" CBX1 10951; "Homo sapiens (Human)" 1.36806 49 37 CHEMBL1241473 COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC COc1cc(Nc2ncc(c(n2)Nc2ccccc2C(=O)N)N(=O)=O)cc(c1OC)OC P15538 "Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase) (EC 1.14.15.4)" "Cytochrome P450 family" CYP11B1 1584; "Homo sapiens (Human)" 1.3486 50 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 2.93002 1 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 2.9252 2 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P05067 "Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta A4 protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]" "APP family" APP 351; "Homo sapiens (Human)" 2.88759 3 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 2.85087 4 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P43166 "Carbonic anhydrase 7 (EC 4.2.1.1) (Carbonate dehydratase VII) (Carbonic anhydrase VII) (CA-VII)" "Alpha-carbonic anhydrase family" CA7 766; "Homo sapiens (Human)" 2.74736 5 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 2.74351 6 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 2.68134 7 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 2.56807 8 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 Q16790 "Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)" "Alpha-carbonic anhydrase family" CA9 768; "Homo sapiens (Human)" 2.39396 9 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 O43570 "Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)" "Alpha-carbonic anhydrase family" CA12 771; "Homo sapiens (Human)" 2.35645 10 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P35218 "Carbonic anhydrase 5A, mitochondrial (EC 4.2.1.1) (Carbonate dehydratase VA) (Carbonic anhydrase VA) (CA-VA)" "Alpha-carbonic anhydrase family" CA5A 763; "Homo sapiens (Human)" 2.31935 11 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 2.30253 12 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 Q9Y2D0 "Carbonic anhydrase 5B, mitochondrial (EC 4.2.1.1) (Carbonate dehydratase VB) (Carbonic anhydrase VB) (CA-VB)" "Alpha-carbonic anhydrase family" CA5B 11238; "Homo sapiens (Human)" 2.28887 13 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 Q8NER1 "Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)" "Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV1 sub-subfamily" TRPV1 7442; "Homo sapiens (Human)" 2.23106 14 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 2.1537 15 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P25101 "Endothelin-1 receptor (Endothelin receptor type A) (ET-A) (ETA-R) (hET-AR)" "G-protein coupled receptor 1 family, Endothelin receptor subfamily, EDNRA sub-subfamily" EDNRA 1909; "Homo sapiens (Human)" 2.11209 16 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P22303 "Acetylcholinesterase (AChE) (EC 3.1.1.7)" "Type-B carboxylesterase/lipase family" ACHE 43; "Homo sapiens (Human)" 1.97464 17 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.87536 18 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 1.84675 19 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P49286 "Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)" "G-protein coupled receptor 1 family" MTNR1B 4544; "Homo sapiens (Human)" 1.76058 20 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 Q9H237 "Protein-serine O-palmitoleoyltransferase porcupine (EC 2.3.1.250) (Protein MG61)" "Membrane-bound acyltransferase family, Porcupine subfamily" PORCN 64840; "Homo sapiens (Human)" 1.74758 21 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P00742 "Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]" "Peptidase S1 family" F10 2159; "Homo sapiens (Human)" 1.74646 22 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P50579 "Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Initiation factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2) (Peptidase M)" "Peptidase M24A family, Methionine aminopeptidase eukaryotic type 2 subfamily" METAP2 10988; "Homo sapiens (Human)" 1.72778 23 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P34972 "Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)" "G-protein coupled receptor 1 family" CNR2 1269; "Homo sapiens (Human)" 1.72405 24 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 1.71709 25 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P50406 "5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)" "G-protein coupled receptor 1 family" HTR6 3362; "Homo sapiens (Human)" 1.70168 26 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P34913 "Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]" "AB hydrolase superfamily, Epoxide hydrolase family" EPHX2 2053; "Homo sapiens (Human)" 1.69601 27 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 Q9ULX7 "Carbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase XIV) (CA-XIV)" "Alpha-carbonic anhydrase family" CA14 23632; "Homo sapiens (Human)" 1.68015 28 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P00915 "Carbonic anhydrase 1 (EC 4.2.1.1) (Carbonate dehydratase I) (Carbonic anhydrase B) (CAB) (Carbonic anhydrase I) (CA-I)" "Alpha-carbonic anhydrase family" CA1 759; "Homo sapiens (Human)" 1.66285 29 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 Q13547 "Histone deacetylase 1 (HD1) (EC 3.5.1.98)" "Histone deacetylase family, HD type 1 subfamily" HDAC1 3065; "Homo sapiens (Human)" 1.60518 30 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P51679 "C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) (K5-5) (CD antigen CD194)" "G-protein coupled receptor 1 family" CCR4 1233; "Homo sapiens (Human)" 1.5633 31 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 1.50028 32 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P03372 "Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)" "Nuclear hormone receptor family, NR3 subfamily" ESR1 2099; "Homo sapiens (Human)" 1.47843 33 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 Q15761 "Neuropeptide Y receptor type 5 (NPY5-R) (NPY-Y5 receptor) (NPYY5-R) (Y5 receptor)" "G-protein coupled receptor 1 family" NPY5R 4889; "Homo sapiens (Human)" 1.47292 34 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.44319 35 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P48039 "Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)" "G-protein coupled receptor 1 family" MTNR1A 4543; "Homo sapiens (Human)" 1.43659 36 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 O15552 "Free fatty acid receptor 2 (G-protein coupled receptor 43)" "G-protein coupled receptor 1 family" FFAR2 2867; "Homo sapiens (Human)" 1.41982 37 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P09960 "Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)" "Peptidase M1 family" LTA4H 4048; "Homo sapiens (Human)" 1.41458 38 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P28335 "5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)" "G-protein coupled receptor 1 family" HTR2C 3358; "Homo sapiens (Human)" 1.39523 39 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P15538 "Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase) (EC 1.14.15.4)" "Cytochrome P450 family" CYP11B1 1584; "Homo sapiens (Human)" 1.37488 40 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 Q02127 "Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase)" "Dihydroorotate dehydrogenase family, Type 2 subfamily" DHODH 1723; "Homo sapiens (Human)" 1.3181 41 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P00918 "Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)" "Alpha-carbonic anhydrase family" CA2 760; "Homo sapiens (Human)" 1.28658 42 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P11511 "Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase)" "Cytochrome P450 family" CYP19A1 1588; "Homo sapiens (Human)" 1.26154 43 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P42336 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)" "PI3/PI4-kinase family" PIK3CA 5290; "Homo sapiens (Human)" 1.24253 44 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P48736 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)" "PI3/PI4-kinase family" PIK3CG 5294; "Homo sapiens (Human)" 1.20394 45 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P19525 "Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK2 5610; "Homo sapiens (Human)" 1.20068 46 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 O00329 "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)" "PI3/PI4-kinase family" PIK3CD 5293; "Homo sapiens (Human)" 1.17247 47 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P04626 "Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB2 2064; "Homo sapiens (Human)" 1.16063 48 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P29274 "Adenosine receptor A2a" "G-protein coupled receptor 1 family" ADORA2A 135; "Homo sapiens (Human)" 1.16003 49 38 CHEMBL1973540 O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 O=C1Nc2c(C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1)c1scnc1cc2 P16083 "Ribosyldihydronicotinamide dehydrogenase [quinone] (EC 1.10.5.1) (NRH dehydrogenase [quinone] 2) (NRH:quinone oxidoreductase 2) (Quinone reductase 2) (QR2)" "NAD(P)H dehydrogenase (quinone) family" NQO2 4835; "Homo sapiens (Human)" 1.12436 50 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 3.44897 1 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 3.40126 2 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 3.14401 3 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 2.8709 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 2.76269 4 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 2.75536 5 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 2.6586 6 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 2.63676 7 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P24723 "Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCH 5583; "Homo sapiens (Human)" 2.62696 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 2.62316 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 2.4622 8 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 2.44486 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 2.44385 9 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P05771 "Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCB 5579; "Homo sapiens (Human)" 2.4337 10 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 2.42941 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 2.40889 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 2.34932 11 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P21860 "Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB3 2065; "Homo sapiens (Human)" 2.33589 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 2.32804 12 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 2.32526 13 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 2.30222 14 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P17252 "Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCA 5578; "Homo sapiens (Human)" 2.27346 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 2.203 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9BWU1 "Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK19 23097; "Homo sapiens (Human)" 2.17498 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 2.17176 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 2.14048 15 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 2.08631 16 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q02156 "Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCE 5581; "Homo sapiens (Human)" 2.07294 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 2.07266 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 2.05075 17 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q06418 "Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" TYRO3 7301; "Homo sapiens (Human)" 2.01382 18 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 2.00914 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q8TD08 "Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK15 225689; "Homo sapiens (Human)" 1.94333 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 1.94059 19 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 1.93628 20 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O76039 "Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDKL5 6792; "Homo sapiens (Human)" 1.92241 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 1.91621 21 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P14616 "Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSRR 3645; "Homo sapiens (Human)" 1.91601 22 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O00311 "Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamily" CDC7 8317; "Homo sapiens (Human)" 1.91306 23 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 1.9053 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 1.89921 24 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q00526 "Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK3 1018; "Homo sapiens (Human)" 1.88491 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q8N5S9 "Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK1 84254; "Homo sapiens (Human)" 1.88405 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q00535 "Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK5 1020; "Homo sapiens (Human)" 1.86706 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 1.86092 25 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 1.83659 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9Y463 "Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1B 9149; "Homo sapiens (Human)" 1.82494 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q13627 "Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1A 1859; "Homo sapiens (Human)" 1.80206 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 1.79836 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 1.79322 26 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.79068 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 1.78497 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 1.78438 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.7803 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P06493 "Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK1 983; "Homo sapiens (Human)" 1.7611 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 1.76015 27 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P35590 "Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)" "Protein kinase superfamily, Tyr protein kinase family, Tie subfamily" TIE1 7075; "Homo sapiens (Human)" 1.75714 28 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P29322 "Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA8 2046; "Homo sapiens (Human)" 1.75229 29 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 1.68365 30 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 1.66977 31 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q92731 "Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)" "Nuclear hormone receptor family, NR3 subfamily" ESR2 2100; "Homo sapiens (Human)" 1.66438 32 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.66412 33 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 1.6394 34 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 1.63541 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.62184 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 1.62106 35 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P54764 "Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA4 2043; "Homo sapiens (Human)" 1.61817 36 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 1.61169 37 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9UQ88 "Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 2) (Cell division protein kinase 11A) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK11A 728642; "Homo sapiens (Human)" 1.60953 38 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 1.60578 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 1.60157 39 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 1.5961 40 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P20794 "Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" MAK 4117; "Homo sapiens (Human)" 1.59035 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q59H18 "Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" TNNI3K 100526835;51086; "Homo sapiens (Human)" 1.58542 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q00537 "Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK17 5128; "Homo sapiens (Human)" 1.58524 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 1.57521 41 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 1.56965 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 1.567 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 1.56132 42 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 1.55512 43 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P29323 "Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB2 2048; "Homo sapiens (Human)" 1.54889 44 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q8NE63 "Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK4 147746; "Homo sapiens (Human)" 1.54627 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 1.54439 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O94921 "Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK14 5218; "Homo sapiens (Human)" 1.53626 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.5237 45 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q04759 "Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCQ 5588; "Homo sapiens (Human)" 1.51451 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 1.50582 46 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P48730 "Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1D 1453; "Homo sapiens (Human)" 1.50494 47 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 1.504 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 1.50378 48 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 1.50156 49 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 1.49652 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 1.48864 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 1.48608 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 1.48562 50 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 1.46676 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P37023 "Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVRL1 94; "Homo sapiens (Human)" 1.45988 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 1.45687 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 1.44941 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 1.43095 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 1.40964 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 1.38658 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 1.38494 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 1.36614 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 1.34194 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q00536 "Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK16 5127; "Homo sapiens (Human)" 1.34174 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P54756 "Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA5 2044; "Homo sapiens (Human)" 1.33203 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P37173 "TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR2 7048; "Homo sapiens (Human)" 1.32932 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P11309 "Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM1 5292; "Homo sapiens (Human)" 1.30925 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 1.29224 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q13705 "Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2B 93; "Homo sapiens (Human)" 1.27978 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.26162 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 1.25825 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q15139 "Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD1 5587; "Homo sapiens (Human)" 1.25598 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q09013 "Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) (DMPK) (Myotonic dystrophy protein kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" DMPK 1760; "Homo sapiens (Human)" 1.25248 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 1.23134 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 1.22397 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9HCP0 "Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1G1 53944; "Homo sapiens (Human)" 1.21986 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.20764 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 1.19239 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q00534 "Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK6 1021; "Homo sapiens (Human)" 1.19152 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.18274 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 1.1806 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.1669 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 1.15663 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9C098 "Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK3 85443; "Homo sapiens (Human)" 1.15442 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q07002 "Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK18 5129; "Homo sapiens (Human)" 1.14875 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 1.13965 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 1.12813 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 1.12565 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 1.12109 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P11217 "Glycogen phosphorylase, muscle form (EC 2.4.1.1) (Myophosphorylase)" "Glycogen phosphorylase family" PYGM 5837; "Homo sapiens (Human)" 1.1156 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 1.10539 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q13164 "Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK7 5598; "Homo sapiens (Human)" 1.10411 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O15075 "Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK1 9201; "Homo sapiens (Human)" 1.07972 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.06467 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 1.06012 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 1.05692 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 1.04976 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 1.03269 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q16566 "Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK4 814; "Homo sapiens (Human)" 1.02006 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P49761 "Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK3 1198; "Homo sapiens (Human)" 1.01955 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P48729 "Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1 1452; "Homo sapiens (Human)" 1.01537 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.00275 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 1.00228 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 0.997106 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 0.995114 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 0.992333 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O14578 "Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" CIT 11113; "Homo sapiens (Human)" 0.990947 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q8WTQ7 "Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK7 131890; "Homo sapiens (Human)" 0.982997 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 0.980394 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9BQI3 "Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled repressor) (HCR) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Hemin-sensitive initiation factor 2-alpha kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK1 27102; "Homo sapiens (Human)" 0.97224 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 0.968416 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 0.945171 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 0.935157 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 0.925122 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q15835 "Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK1 6011; "Homo sapiens (Human)" 0.923784 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q8TBX8 "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma)" PIP4K2C 79837; "Homo sapiens (Human)" 0.92297 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 0.881318 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 0.880219 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 0.868158 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q86Y07 "Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, VRK subfamily" VRK2 7444; "Homo sapiens (Human)" 0.866115 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 0.862066 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 0.853253 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q13557 "Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2D 817; "Homo sapiens (Human)" 0.84897 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9UEE5 "Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17A 9263; "Homo sapiens (Human)" 0.841976 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 0.835479 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 0.825509 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9HBH9 "MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MKNK2 2872; "Homo sapiens (Human)" 0.824605 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q96Q40 "Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK15 65061; "Homo sapiens (Human)" 0.816239 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 0.808688 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q16816 "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG1 5260; "Homo sapiens (Human)" 0.808362 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 0.8008 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 0.773256 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P19525 "Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK2 5610; "Homo sapiens (Human)" 0.756579 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P27037 "Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR2A 92; "Homo sapiens (Human)" 0.747273 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q05655 "Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCD 5580; "Homo sapiens (Human)" 0.731258 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9UQM7 "Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2A 815; "Homo sapiens (Human)" 0.718648 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O60331 "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma)" PIP5K1C 23396; "Homo sapiens (Human)" 0.711626 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 0.678575 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q6XUX3 "Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)" "Protein kinase superfamily, Ser/Thr protein kinase family" DSTYK 25778; "Homo sapiens (Human)" 0.671595 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q13555 "Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2G 818; "Homo sapiens (Human)" 0.657181 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 0.646893 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 0.631655 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q8N752 "Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1A1L 122011; "Homo sapiens (Human)" 0.628546 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O P45985 "Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K4 6416; "Homo sapiens (Human)" 0.61387 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O O94768 "Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17B 9262; "Homo sapiens (Human)" 0.589392 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9Y5S2 "Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (CDC42BP-beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPB 9578; "Homo sapiens (Human)" 0.581872 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q13554 "Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK2B 816; "Homo sapiens (Human)" 0.569836 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 0.438968 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q8WU08 "Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK32A 202374; "Homo sapiens (Human)" 0.437893 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q02779 "Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K10 4294; "Homo sapiens (Human)" 0.433666 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 0.426606 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q16512 "Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN1 5585; "Homo sapiens (Human)" 0.368708 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q9NUW8 "Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-)" "Tyrosyl-DNA phosphodiesterase family" TDP1 55775; "Homo sapiens (Human)" 0.326088 Known 39 CHEMBL428690 CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O Q5VT25 "Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily" CDC42BPA 8476; "Homo sapiens (Human)" 0.232471 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 2.96817 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P10721 "Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KIT 3815; "Homo sapiens (Human)" 2.85887 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P30530 "Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" AXL 558; "Homo sapiens (Human)" 2.85772 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P07333 "Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" CSF1R 1436; "Homo sapiens (Human)" 2.80611 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 2.78431 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q08345 "Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR1 780; "Homo sapiens (Human)" 2.78236 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O60674 "Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK2 3717; "Homo sapiens (Human)" 2.55728 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q56UN5 "Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP3K19 80122; "Homo sapiens (Human)" 2.55245 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P52333 "Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK3 3718; "Homo sapiens (Human)" 2.47589 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P33981 "Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)" "Protein kinase superfamily, Ser/Thr protein kinase family" TTK 7272; "Homo sapiens (Human)" 2.42845 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9NSY1 "BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" BMP2K 55589; "Homo sapiens (Human)" 2.42331 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O43318 "Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K7 6885; "Homo sapiens (Human)" 2.37992 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P54646 "5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA2 5563; "Homo sapiens (Human)" 2.36506 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P16234 "Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRA 5156; "Homo sapiens (Human)" 2.33978 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P04629 "High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK1 4914; "Homo sapiens (Human)" 2.33632 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P09619 "Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" PDGFRB 5159; "Homo sapiens (Human)" 2.32319 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O14965 "Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKA 6790; "Homo sapiens (Human)" 2.29181 1 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q13043 "Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK4 6789; "Homo sapiens (Human)" 2.29103 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P16591 "Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FER 2241; "Homo sapiens (Human)" 2.25246 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q06187 "Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BTK 695; "Homo sapiens (Human)" 2.24342 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q05655 "Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCD 5580; "Homo sapiens (Human)" 2.23452 2 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P29376 "Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" LTK 4058; "Homo sapiens (Human)" 2.20281 3 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O14757 "Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily" CHEK1 1111; "Homo sapiens (Human)" 2.18397 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O00444 "Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK4 10733; "Homo sapiens (Human)" 2.17006 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q13163 "Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K5 5607; "Homo sapiens (Human)" 2.15183 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O75716 "Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK16 8576; "Homo sapiens (Human)" 2.13824 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P15056 "Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" BRAF 673; "Homo sapiens (Human)" 2.06555 4 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P17948 "Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT1 2321; "Homo sapiens (Human)" 2.06327 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q5S007 "Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LRRK2 120892; "Homo sapiens (Human)" 2.04878 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 2.02594 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q12866 "Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)" "Protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily" MERTK 10461; "Homo sapiens (Human)" 2.02191 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P51451 "Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" BLK 640; "Homo sapiens (Human)" 2.01467 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P50613 "Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK7 1022; "Homo sapiens (Human)" 1.98678 5 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P22455 "Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR4 2264; "Homo sapiens (Human)" 1.97597 6 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q8N4C8 "Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MINK1 50488; "Homo sapiens (Human)" 1.96782 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q16288 "NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK3 4916; "Homo sapiens (Human)" 1.96534 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q32MK0 "Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK3 91807; "Homo sapiens (Human)" 1.96259 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q16620 "BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" NTRK2 4915; "Homo sapiens (Human)" 1.91495 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q16539 "Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK14 1432; "Homo sapiens (Human)" 1.88875 7 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P53779 "Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK10 5602; "Homo sapiens (Human)" 1.87663 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9H093 "NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK2 81788; "Homo sapiens (Human)" 1.87271 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q13882 "Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)" "Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily" PTK6 5753; "Homo sapiens (Human)" 1.864 8 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9Y2U5 "Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K2 10746; "Homo sapiens (Human)" 1.86047 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9UKE5 "TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TNIK 23043; "Homo sapiens (Human)" 1.85804 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P49840 "Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3A 2931; "Homo sapiens (Human)" 1.84203 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q02750 "Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K1 5604; "Homo sapiens (Human)" 1.83914 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.8251 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q8IVH8 "Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K3 8491; "Homo sapiens (Human)" 1.81686 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9Y4K4 "Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K5 11183; "Homo sapiens (Human)" 1.80134 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q92918 "Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K1 11184; "Homo sapiens (Human)" 1.78586 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O95819 "Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K4 9448; "Homo sapiens (Human)" 1.77112 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q14680 "Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MELK 9833; "Homo sapiens (Human)" 1.74896 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q13131 "5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" PRKAA1 5562; "Homo sapiens (Human)" 1.74177 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P45983 "Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK8 5599; "Homo sapiens (Human)" 1.72884 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q13464 "Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK1 6093; "Homo sapiens (Human)" 1.70397 9 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9H3Y6 "Tyrosine-protein kinase Srms (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRMS 6725; "Homo sapiens (Human)" 1.68885 10 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P08581 "Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)" "Protein kinase superfamily, Tyr protein kinase family" MET 4233; "Homo sapiens (Human)" 1.68843 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9HAZ1 "Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK4 57396; "Homo sapiens (Human)" 1.68467 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P17612 "cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily" PRKACA 5566; "Homo sapiens (Human)" 1.68452 11 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q13188 "Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK3 6788; "Homo sapiens (Human)" 1.68331 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9BWU1 "Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK19 23097; "Homo sapiens (Human)" 1.6817 12 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q6PHR2 "Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK3 25989; "Homo sapiens (Human)" 1.67253 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P35916 "Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT4 2324; "Homo sapiens (Human)" 1.66463 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P29597 "Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" TYK2 7297; "Homo sapiens (Human)" 1.65284 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P49336 "Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK8 1024; "Homo sapiens (Human)" 1.64719 13 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P36896 "Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1B 91; "Homo sapiens (Human)" 1.63276 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O14920 "Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKB 3551; "Homo sapiens (Human)" 1.62675 14 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q16832 "Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" DDR2 4921; "Homo sapiens (Human)" 1.62398 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P53350 "Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)" "Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily" PLK1 5347; "Homo sapiens (Human)" 1.6188 15 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q04759 "Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCQ 5588; "Homo sapiens (Human)" 1.61425 16 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q96RR4 "Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK2 10645; "Homo sapiens (Human)" 1.60774 17 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q15375 "Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA7 2045; "Homo sapiens (Human)" 1.60589 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P53667 "LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" LIMK1 3984; "Homo sapiens (Human)" 1.60311 18 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O75582 "Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA5 9252; "Homo sapiens (Human)" 1.59666 19 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q96SB4 "SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK1 6732; "Homo sapiens (Human)" 1.58953 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q12851 "Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" MAP4K2 5871; "Homo sapiens (Human)" 1.58887 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P05129 "Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCG 5582; "Homo sapiens (Human)" 1.58615 20 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q99755 "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)" PIP5K1A 8394; "Homo sapiens (Human)" 1.58024 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q14004 "Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK13 8621; "Homo sapiens (Human)" 1.57796 21 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9NWT8 "Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, mitochondrial) (MRP-S38) (Mitochondrial small ribosomal subunit protein mS38)" "Mitochondrion-specific ribosomal protein mS38 family" AURKAIP1 54998; "Homo sapiens (Human)" 1.57476 22 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P50750 "Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK9 1025; "Homo sapiens (Human)" 1.57182 23 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P49759 "Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK1 1195; "Homo sapiens (Human)" 1.57093 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q2M2I8 "AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" AAK1 22848; "Homo sapiens (Human)" 1.56588 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q14289 "Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2B 2185; "Homo sapiens (Human)" 1.56485 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P51812 "Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA3 6197; "Homo sapiens (Human)" 1.56009 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P45984 "Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily" MAPK9 5601; "Homo sapiens (Human)" 1.53539 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P36507 "Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K2 5605; "Homo sapiens (Human)" 1.53475 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9Y2K2 "Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK3 23387; "Homo sapiens (Human)" 1.533 24 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P23458 "Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)" "Protein kinase superfamily, Tyr protein kinase family, JAK subfamily" JAK1 3716; "Homo sapiens (Human)" 1.52047 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 1.51732 25 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q86Z02 "Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK1 204851; "Homo sapiens (Human)" 1.51582 26 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9BZL6 "Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD2 25865; "Homo sapiens (Human)" 1.51315 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9H2G2 "STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" SLK 9748; "Homo sapiens (Human)" 1.50842 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P51617 "Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK1 3654; "Homo sapiens (Human)" 1.50796 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q99759 "Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K3 4215; "Homo sapiens (Human)" 1.50321 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q12852 "Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K12 7786; "Homo sapiens (Human)" 1.4977 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9UL54 "Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK2 9344; "Homo sapiens (Human)" 1.48873 27 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P23443 "Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KB1 6198; "Homo sapiens (Human)" 1.47933 28 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P06241 "Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FYN 2534; "Homo sapiens (Human)" 1.47681 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P31645 "Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)" "Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamily" SLC6A4 6532; "Homo sapiens (Human)" 1.46549 29 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O96017 "Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily" CHEK2 11200; "Homo sapiens (Human)" 1.46018 30 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q15303 "Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB4 2066; "Homo sapiens (Human)" 1.45814 31 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q13976 "cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG1 5592; "Homo sapiens (Human)" 1.43746 32 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q02156 "Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCE 5581; "Homo sapiens (Human)" 1.43693 33 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O75116 "Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" ROCK2 9475; "Homo sapiens (Human)" 1.43385 34 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O43283 "Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K13 9175; "Homo sapiens (Human)" 1.42607 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P07947 "Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" YES1 7525; "Homo sapiens (Human)" 1.42096 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q08881 "Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" ITK 3702; "Homo sapiens (Human)" 1.42086 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q13546 "Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK1 8737; "Homo sapiens (Human)" 1.42082 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P06239 "Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LCK 3932; "Homo sapiens (Human)" 1.40565 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.39372 35 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P09769 "Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FGR 2268; "Homo sapiens (Human)" 1.38982 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q13237 "cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, cGMP subfamily" PRKG2 5593; "Homo sapiens (Human)" 1.38252 36 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O75914 "Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK3 5063; "Homo sapiens (Human)" 1.375 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P21860 "Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" ERBB3 2065; "Homo sapiens (Human)" 1.37433 37 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9UEE5 "Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17A 9263; "Homo sapiens (Human)" 1.37346 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9UHD2 "Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" TBK1 29110; "Homo sapiens (Human)" 1.37323 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 1.36941 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q13873 "Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR2 659; "Homo sapiens (Human)" 1.36917 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P11309 "Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM1 5292; "Homo sapiens (Human)" 1.36591 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P32298 "G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK4 2868; "Homo sapiens (Human)" 1.36536 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9BVS4 "Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK2 55781; "Homo sapiens (Human)" 1.3451 38 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P80192 "Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K9 4293; "Homo sapiens (Human)" 1.33789 39 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9P2K8 "eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)" "Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily" EIF2AK4 440275; "Homo sapiens (Human)" 1.33763 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P17252 "Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCA 5578; "Homo sapiens (Human)" 1.33652 40 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 1.32958 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P04049 "RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily" RAF1 5894; "Homo sapiens (Human)" 1.32752 41 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q8WTQ7 "Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK7 131890; "Homo sapiens (Human)" 1.32697 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q04912 "Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family" MST1R 4486; "Homo sapiens (Human)" 1.3229 42 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9Y616 "Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK3 11213; "Homo sapiens (Human)" 1.31727 43 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9UPZ9 "Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" ICK 22858; "Homo sapiens (Human)" 1.31343 44 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O14730 "Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK3 8780; "Homo sapiens (Human)" 1.31264 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9BRS2 "Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)" "Protein kinase superfamily, RIO-type Ser/Thr kinase family" RIOK1 83732; "Homo sapiens (Human)" 1.31068 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9UM73 "ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ALK 238; "Homo sapiens (Human)" 1.30718 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O94806 "Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD3 23683; "Homo sapiens (Human)" 1.30464 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q13627 "Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily" DYRK1A 1859; "Homo sapiens (Human)" 1.3046 45 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P49674 "Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)" "Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily" CSNK1E 102800317;1454; "Homo sapiens (Human)" 1.29943 46 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P05771 "Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PRKCB 5579; "Homo sapiens (Human)" 1.29161 47 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P51813 "Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" BMX 660; "Homo sapiens (Human)" 1.28452 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O94804 "Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK10 6793; "Homo sapiens (Human)" 1.2843 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O43353 "Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK2 8767; "Homo sapiens (Human)" 1.27645 48 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P41240 "Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)" "Protein kinase superfamily, Tyr protein kinase family, CSK subfamily" CSK 1445; "Homo sapiens (Human)" 1.27571 49 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P00533 "Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)" "Protein kinase superfamily, Tyr protein kinase family, EGF receptor subfamily" EGFR 1956; "Homo sapiens (Human)" 1.2597 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q16816 "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG1 5260; "Homo sapiens (Human)" 1.25835 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P57078 "Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" RIPK4 "Homo sapiens (Human)" 1.25599 50 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P14616 "Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSRR 3645; "Homo sapiens (Human)" 1.24384 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P78362 "SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK2 6733; "Homo sapiens (Human)" 1.24245 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9H0K1 "Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" SIK2 23235; "Homo sapiens (Human)" 1.2377 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q15139 "Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily" PRKD1 5587; "Homo sapiens (Human)" 1.23624 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q04771 "Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVR1 90; "Homo sapiens (Human)" 1.23493 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q8IYT8 "Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK2 9706; "Homo sapiens (Human)" 1.23443 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q07912 "Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)" "Protein kinase superfamily, Tyr protein kinase family" TNK2 10188; "Homo sapiens (Human)" 1.20421 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q86YV6 "Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK4 340156; "Homo sapiens (Human)" 1.20036 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q14164 "Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)" "Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily" IKBKE 9641; "Homo sapiens (Human)" 1.17414 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P08069 "Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" IGF1R 3480; "Homo sapiens (Human)" 1.17336 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q52WX2 "Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family" SBK1 388228; "Homo sapiens (Human)" 1.16871 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P07332 "Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)" "Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily" FES 2242; "Homo sapiens (Human)" 1.16621 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P00519 "Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL1 25; "Homo sapiens (Human)" 1.16571 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O14976 "Cyclin-G-associated kinase (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family" GAK 2580; "Homo sapiens (Human)" 1.14391 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9P289 "Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK26 51765; "Homo sapiens (Human)" 1.14291 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P46734 "Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K3 5606; "Homo sapiens (Human)" 1.1413 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P49760 "Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily" CLK2 1196; "Homo sapiens (Human)" 1.14004 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q15349 "Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA2 6196; "Homo sapiens (Human)" 1.13657 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9H2K8 "Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK3 51347; "Homo sapiens (Human)" 1.13389 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P07948 "Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" LYN 4067; "Homo sapiens (Human)" 1.12617 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q8N5S9 "Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)" "Protein kinase superfamily, Ser/Thr protein kinase family" CAMKK1 84254; "Homo sapiens (Human)" 1.12504 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q15418 "Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA1 6195; "Homo sapiens (Human)" 1.12188 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O00238 "Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" BMPR1B 658; "Homo sapiens (Human)" 1.1105 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P78356 "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta)" PIP4K2B 8396; "Homo sapiens (Human)" 1.10726 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P42681 "Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TXK 7294; "Homo sapiens (Human)" 1.10422 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O15197 "Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB6 2051; "Homo sapiens (Human)" 1.07717 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9UQB9 "Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKC 6795; "Homo sapiens (Human)" 1.07247 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O60285 "NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" NUAK1 9891; "Homo sapiens (Human)" 1.07001 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9BYT3 "Serine/threonine-protein kinase 33 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" STK33 65975; "Homo sapiens (Human)" 1.06254 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9P286 "Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK5 57144; "Homo sapiens (Human)" 1.06138 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O75676 "Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA4 8986; "Homo sapiens (Human)" 1.05604 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P11802 "Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK4 1019; "Homo sapiens (Human)" 1.05147 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9UPE1 "SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" SRPK3 26576; "Homo sapiens (Human)" 1.0401 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P11362 "Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR1 2260; "Homo sapiens (Human)" 1.02859 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9NRM7 "Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS2 26524; "Homo sapiens (Human)" 1.02826 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q15746 "Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" MYLK 4638; "Homo sapiens (Human)" 1.02457 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9H422 "Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK3 10114; "Homo sapiens (Human)" 1.01678 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P06213 "Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" INSR 3643; "Homo sapiens (Human)" 0.997117 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P22607 "Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR3 2261; "Homo sapiens (Human)" 0.995294 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P12931 "Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" SRC 6714; "Homo sapiens (Human)" 0.985729 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9H2X6 "Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily" HIPK2 28996; "Homo sapiens (Human)" 0.977646 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9NWZ3 "Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily" IRAK4 51135; "Homo sapiens (Human)" 0.956143 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q13470 "Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)" "Protein kinase superfamily, Tyr protein kinase family" TNK1 8711; "Homo sapiens (Human)" 0.954211 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q13523 "Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family" PRPF4B 8899; "Homo sapiens (Human)" 0.945427 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9Y6E0 "Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK24 8428; "Homo sapiens (Human)" 0.938608 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P15735 "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" PHKG2 5261; "Homo sapiens (Human)" 0.93598 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O75385 "Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)" "Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily" ULK1 8408; "Homo sapiens (Human)" 0.902496 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q6XUX3 "Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)" "Protein kinase superfamily, Ser/Thr protein kinase family" DSTYK 25778; "Homo sapiens (Human)" 0.878532 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q15835 "Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily" GRK1 6011; "Homo sapiens (Human)" 0.874427 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O96013 "Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK4 10298; "Homo sapiens (Human)" 0.867932 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q7L7X3 "Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" TAOK1 57551; "Homo sapiens (Human)" 0.839457 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P0C264 "Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family member 3) (Sugen kinase 110)" "Protein kinase superfamily, Ser/Thr protein kinase family, STKL subfamily" SBK3 100130827; "Homo sapiens (Human)" 0.824915 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q05397 "Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)" "Protein kinase superfamily, Tyr protein kinase family, FAK subfamily" PTK2 5747; "Homo sapiens (Human)" 0.815655 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q96GD4 "Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)" "Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily" AURKB 9212; "Homo sapiens (Human)" 0.787731 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P42685 "Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" FRK 2444; "Homo sapiens (Human)" 0.787097 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P54762 "Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB1 2047; "Homo sapiens (Human)" 0.781468 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P54764 "Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA4 2043; "Homo sapiens (Human)" 0.753592 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P54760 "Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB4 2050; "Homo sapiens (Human)" 0.749742 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q8TDR2 "Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)" "Protein kinase superfamily, Ser/Thr protein kinase family" STK35 140901; "Homo sapiens (Human)" 0.741817 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P08631 "Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)" "Protein kinase superfamily, Tyr protein kinase family, SRC subfamily" HCK 3055; "Homo sapiens (Human)" 0.715142 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9UK32 "Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily" RPS6KA6 27330; "Homo sapiens (Human)" 0.71288 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P57059 "Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, AMPK subfamily" SIK1 102724428;150094; "Homo sapiens (Human)" 0.705437 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P29323 "Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHB2 2048; "Homo sapiens (Human)" 0.699953 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q16512 "Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN1 5585; "Homo sapiens (Human)" 0.670038 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P21802 "Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)" "Protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily" FGFR2 2263; "Homo sapiens (Human)" 0.65683 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P37173 "TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR2 7048; "Homo sapiens (Human)" 0.652425 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q7KZI7 "Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK2 2011; "Homo sapiens (Human)" 0.643528 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9UF33 "Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA6 285220; "Homo sapiens (Human)" 0.62999 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q6ZN16 "Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K15 389840; "Homo sapiens (Human)" 0.624392 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P45985 "Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K4 6416; "Homo sapiens (Human)" 0.60245 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O75460 "Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]" "Protein kinase superfamily, Ser/Thr protein kinase family" ERN1 2081; "Homo sapiens (Human)" 0.602267 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9UIK4 "Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK2 23604; "Homo sapiens (Human)" 0.597625 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O15530 "3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily" PDPK1 5170; "Homo sapiens (Human)" 0.596268 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P36897 "TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" TGFBR1 7046; "Homo sapiens (Human)" 0.592421 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P29320 "Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA3 2042; "Homo sapiens (Human)" 0.583761 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O95835 "Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family" LATS1 9113; "Homo sapiens (Human)" 0.57109 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O15075 "Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" DCLK1 9201; "Homo sapiens (Human)" 0.570831 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P21709 "Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA1 2041; "Homo sapiens (Human)" 0.56395 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O43293 "Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK3 1613; "Homo sapiens (Human)" 0.563601 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P54756 "Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA5 2044; "Homo sapiens (Human)" 0.560749 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q96NX5 "Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I gamma) (CaM kinase IG) (CaM-KI gamma) (CaMKI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1G 57172; "Homo sapiens (Human)" 0.55985 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P53355 "Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" DAPK1 1612; "Homo sapiens (Human)" 0.557622 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P43405 "Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)" "Protein kinase superfamily, Tyr protein kinase family, SYK/ZAP-70 subfamily" SYK 6850; "Homo sapiens (Human)" 0.547106 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q96L34 "MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK4 57787; "Homo sapiens (Human)" 0.523315 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q8NFD2 "Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family" ANKK1 255239; "Homo sapiens (Human)" 0.492049 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9BXA7 "Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family" TSSK1B 83942; "Homo sapiens (Human)" 0.470538 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O94768 "Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily" STK17B 9262; "Homo sapiens (Human)" 0.469935 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P27448 "MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK3 4140; "Homo sapiens (Human)" 0.462869 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q8IU85 "Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily" CAMK1D 57118; "Homo sapiens (Human)" 0.4606 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P37023 "Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)" "Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily" ACVRL1 94; "Homo sapiens (Human)" 0.46038 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9NQU5 "Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) (PAK-6)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" PAK6 106821730;56924; "Homo sapiens (Human)" 0.454471 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q16513 "Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily" PKN2 5586; "Homo sapiens (Human)" 0.452676 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O15146 "Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)" "Protein kinase superfamily, Tyr protein kinase family" MUSK 4593; "Homo sapiens (Human)" 0.438913 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P29317 "Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)" "Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily" EPHA2 1969; "Homo sapiens (Human)" 0.434123 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P19784 "Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)" "Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily" CSNK2A2 1459; "Homo sapiens (Human)" 0.429409 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P52564 "Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6) (Stress-activated protein kinase kinase 3) (SAPK kinase 3) (SAPKK-3) (SAPKK3)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily" MAP2K6 5608; "Homo sapiens (Human)" 0.414835 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P08922 "Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)" "Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily" ROS1 6098; "Homo sapiens (Human)" 0.412063 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9P0L2 "Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily" MARK1 4139; "Homo sapiens (Human)" 0.410657 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P42680 "Tyrosine-protein kinase Tec (EC 2.7.10.2)" "Protein kinase superfamily, Tyr protein kinase family, TEC subfamily" TEC 7006; "Homo sapiens (Human)" 0.379725 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C Q9Y6R4 "Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K4 4216; "Homo sapiens (Human)" 0.373175 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P42684 "Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)" "Protein kinase superfamily, Tyr protein kinase family, ABL subfamily" ABL2 27; "Homo sapiens (Human)" 0.352892 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O00506 "Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily" STK25 10494; "Homo sapiens (Human)" 0.343409 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C P08684 "Cytochrome P450 3A4 (EC 1.14.14.-) (1,8-cineole 2-exo-monooxygenase) (EC 1.14.14.56) (Albendazole monooxygenase (sulfoxide-forming)) (EC 1.14.14.73) (Albendazole sulfoxidase) (CYPIIIA3) (CYPIIIA4) (Cholesterol 25-hydroxylase) (EC 1.14.14.-) (Cytochrome P450 3A3) (Cytochrome P450 HLp) (Cytochrome P450 NF-25) (Cytochrome P450-PCN1) (Nifedipine oxidase) (Quinine 3-monooxygenase) (EC 1.14.14.55) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.14.-)" "Cytochrome P450 family" CYP3A4 1576; "Homo sapiens (Human)" 0.285198 Known 40 CHEMBL1908395 CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.Cl N#Cc1c[nH]c(n1)C(=O)Nc1ccc(cc1C1=CCCCC1)C1CCN(CC1)C(=O)CN(C)C O95382 "Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 2)" "Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily" MAP3K6 9064; "Homo sapiens (Human)" 0.193759 Known 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 Q9P1W9 "Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) (Pim-2h)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM2 11040; "Homo sapiens (Human)" 3.687 1 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P19099 "Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)" "Cytochrome P450 family" CYP11B2 1585; "Homo sapiens (Human)" 3.44152 2 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P41595 "5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)" "G-protein coupled receptor 1 family" HTR2B 3357; "Homo sapiens (Human)" 3.04875 3 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P49286 "Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)" "G-protein coupled receptor 1 family" MTNR1B 4544; "Homo sapiens (Human)" 3.02714 4 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P48039 "Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)" "G-protein coupled receptor 1 family" MTNR1A 4543; "Homo sapiens (Human)" 2.76338 5 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 Q9Y243 "RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT3 10000; "Homo sapiens (Human)" 2.7082 6 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P31749 "RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT1 207; "Homo sapiens (Human)" 2.69361 7 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P28222 "5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (S12) (Serotonin 1D beta receptor) (5-HT-1D-beta) (Serotonin receptor 1B)" "G-protein coupled receptor 1 family" HTR1B 3351; "Homo sapiens (Human)" 2.46795 8 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 O00519 "Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)" "Amidase family" FAAH 2166; "Homo sapiens (Human)" 2.46436 9 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P31751 "RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC-PK-beta)" "Protein kinase superfamily, AGC Ser/Thr protein kinase family, RAC subfamily" AKT2 208; "Homo sapiens (Human)" 2.46109 10 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P28221 "5-hydroxytryptamine receptor 1D (5-HT-1D) (5-HT1D) (Serotonin 1D alpha receptor) (5-HT-1D-alpha) (Serotonin receptor 1D)" "G-protein coupled receptor 1 family" HTR1D 3352; "Homo sapiens (Human)" 2.45661 11 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P28223 "5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)" "G-protein coupled receptor 1 family" HTR2A 3356; "Homo sapiens (Human)" 2.44983 12 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P35372 "Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)" "G-protein coupled receptor 1 family" OPRM1 4988; "Homo sapiens (Human)" 2.34073 13 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P09960 "Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)" "Peptidase M1 family" LTA4H 4048; "Homo sapiens (Human)" 2.33831 14 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P07550 "Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB2 sub-subfamily" ADRB2 154; "Homo sapiens (Human)" 2.33521 15 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P08908 "5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)" "G-protein coupled receptor 1 family, 5-hydroxytryptamine receptor subfamily, HTR1A sub-subfamily" HTR1A 3350; "Homo sapiens (Human)" 2.19851 16 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 Q13547 "Histone deacetylase 1 (HD1) (EC 3.5.1.98)" "Histone deacetylase family, HD type 1 subfamily" HDAC1 3065; "Homo sapiens (Human)" 2.17978 17 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P43681 "Neuronal acetylcholine receptor subunit alpha-4" "Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Alpha-4/CHRNA4 sub-subfamily" CHRNA4 1137; "Homo sapiens (Human)" 1.95786 18 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P11309 "Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM1 5292; "Homo sapiens (Human)" 1.9536 19 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P41594 "Metabotropic glutamate receptor 5 (mGluR5)" "G-protein coupled receptor 3 family" GRM5 2915; "Homo sapiens (Human)" 1.94144 20 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P21917 "D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)" "G-protein coupled receptor 1 family" DRD4 1815; "Homo sapiens (Human)" 1.85944 21 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 Q9Y5N1 "Histamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)" "G-protein coupled receptor 1 family" HRH3 11255; "Homo sapiens (Human)" 1.83813 22 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P35968 "Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" KDR 3791; "Homo sapiens (Human)" 1.8349 23 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P31645 "Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)" "Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamily" SLC6A4 6532; "Homo sapiens (Human)" 1.79699 24 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 Q86V86 "Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)" "Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily" PIM3 415116; "Homo sapiens (Human)" 1.62907 25 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 Q92731 "Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)" "Nuclear hormone receptor family, NR3 subfamily" ESR2 2100; "Homo sapiens (Human)" 1.61351 26 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P41145 "Kappa-type opioid receptor (K-OR-1) (KOR-1)" "G-protein coupled receptor 1 family" OPRK1 4986; "Homo sapiens (Human)" 1.5964 27 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P28335 "5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)" "G-protein coupled receptor 1 family" HTR2C 3358; "Homo sapiens (Human)" 1.58494 28 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P50406 "5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)" "G-protein coupled receptor 1 family" HTR6 3362; "Homo sapiens (Human)" 1.57595 29 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P27815 "cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.53) (DPDE2) (PDE46)" "Cyclic nucleotide phosphodiesterase family, PDE4 subfamily" PDE4A 5141; "Homo sapiens (Human)" 1.54994 30 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P14416 "D(2) dopamine receptor (Dopamine D2 receptor)" "G-protein coupled receptor 1 family" DRD2 1813; "Homo sapiens (Human)" 1.54403 31 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P35462 "D(3) dopamine receptor (Dopamine D3 receptor)" "G-protein coupled receptor 1 family" DRD3 1814; "Homo sapiens (Human)" 1.53945 32 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P05177 "Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cholesterol 25-hydroxylase) (Cytochrome P(3)450) (Cytochrome P450 4) (Cytochrome P450-P3)" "Cytochrome P450 family" CYP1A2 1544; "Homo sapiens (Human)" 1.5351 33 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P32297 "Neuronal acetylcholine receptor subunit alpha-3" "Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Alpha-3/CHRNA3 sub-subfamily" CHRNA3 1136; "Homo sapiens (Human)" 1.50534 34 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P36888 "Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)" "Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily" FLT3 2322; "Homo sapiens (Human)" 1.44534 35 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P03372 "Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)" "Nuclear hormone receptor family, NR3 subfamily" ESR1 2099; "Homo sapiens (Human)" 1.38976 36 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 O43570 "Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)" "Alpha-carbonic anhydrase family" CA12 771; "Homo sapiens (Human)" 1.36278 37 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P15538 "Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase) (EC 1.14.15.4)" "Cytochrome P450 family" CYP11B1 1584; "Homo sapiens (Human)" 1.35374 38 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P49841 "Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, GSK-3 subfamily" GSK3B 2932; "Homo sapiens (Human)" 1.32984 39 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P23141 "Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) (Carboxylesterase 1) (CE-1) (hCE-1) (EC 3.1.1.1) (Cocaine carboxylesterase) (Egasyn) (HMSE) (Methylumbelliferyl-acetate deacetylase 1) (EC 3.1.1.56) (Monocyte/macrophage serine esterase) (Retinyl ester hydrolase) (REH) (Serine esterase 1) (Triacylglycerol hydrolase) (TGH)" "Type-B carboxylesterase/lipase family" CES1 1066; "Homo sapiens (Human)" 1.32702 40 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P00918 "Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)" "Alpha-carbonic anhydrase family" CA2 760; "Homo sapiens (Human)" 1.27886 41 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P13945 "Beta-3 adrenergic receptor (Beta-3 adrenoreceptor) (Beta-3 adrenoceptor)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB3 sub-subfamily" ADRB3 155; "Homo sapiens (Human)" 1.2731 42 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 Q16790 "Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)" "Alpha-carbonic anhydrase family" CA9 768; "Homo sapiens (Human)" 1.25008 43 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 Q92769 "Histone deacetylase 2 (HD2) (EC 3.5.1.98)" "Histone deacetylase family, HD type 1 subfamily" HDAC2 3066; "Homo sapiens (Human)" 1.24763 44 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P34969 "5-hydroxytryptamine receptor 7 (5-HT-7) (5-HT7) (5-HT-X) (Serotonin receptor 7)" "G-protein coupled receptor 1 family" HTR7 3363; "Homo sapiens (Human)" 1.23723 45 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P07949 "Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]" "Protein kinase superfamily, Tyr protein kinase family" RET 5979; "Homo sapiens (Human)" 1.21301 46 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P34913 "Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]" "AB hydrolase superfamily, Epoxide hydrolase family" EPHX2 2053; "Homo sapiens (Human)" 1.21225 47 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P08588 "Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor)" "G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB1 sub-subfamily" ADRB1 153; "Homo sapiens (Human)" 1.20703 48 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 Q6GMR7 "Fatty-acid amide hydrolase 2 (EC 3.5.1.99) (Amidase domain-containing protein) (Anandamide amidohydrolase 2) (Oleamide hydrolase 2)" "Amidase family" FAAH2 158584; "Homo sapiens (Human)" 1.19326 49 41 CHEMBL2001751 NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 NC(Cc1c[nH]c2c1cccc2)COc1cncc(c1)c1ccc2c(c1)C(=Cc1ccco1)C(=O)N2 P24941 "Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)" "Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily" CDK2 1017; "Homo sapiens (Human)" 1.19263 50