Index	SMILES	AR	AR-LBD	AhR	Aromatase	ER	ER-LBD	PPAR-gamma	ARE	ATAD5	HSE	p53
Compound_1	Fc1ccc(cc1)S(=O)(=O)[C@@]12CC[C@H]([C@@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)[C@@](CS(=O)(=O)C)(O)C	0.478	0.698	0.285	0.465	0.56	0.597	0.605	0.572	0.399	0.457	0.304
Compound_2	O=C(c1cnn2c1nccc2)Nc1cc2cn(c(c2cc1N1CCOCC1)O)CC1CCOCC1	0.685	0.691	0.081	0.434	0.651	0.65	0.983	0.3	0.287	0.553	0.463
Compound_3	O[C@@H]1C[C@H](C1)NC(=O)c1nc(c(s1)c1c[nH]c(=NC(C(F)(F)F)C)cc1C(F)F)C(=O)N1CCC[C@@H]1C	0.612	0.478	0.202	0.456	0.507	0.646	0.079	0.887	0.247	0.0	0.19
Compound_4	O=C(N1CCCc2c1ccc(c2)N(S(=O)(=O)c1cccc2c1ccn2C)CC(F)(F)F)c1cccs1	0.712	0.655	0.78	0.511	0.551	0.709	0.994	0.798	0.37	0.009	0.31
Compound_5	COc1nc2ccc(cc2c(c1C1CCCC1)Cl)C(c1cnc(n1C)C)(c1cnnn1C)O	0.658	0.738	0.287	0.552	0.699	0.642	0.982	0.231	0.556	0.99	0.393
Compound_6	N#Cc1cc(ccc1OC)C(=O)Nc1cnc2c(c1C)c(cn2C)C1[C@@H]2CC[C@H]1CN(C2)C(=O)C1CCCC1	0.669	0.751	0.932	0.637	0.402	0.719	0.663	0.732	0.451	0.816	0.554
Compound_7	Fc1cccc(c1c1nnc2c(c1)[C@@H]1CC[C@]2(C1(C)C)c1cncc(n1)c1cnn(c1)CCS(=O)(=O)C)F	0.557	0.687	0.277	0.604	0.664	0.633	0.99	0.781	0.433	0.482	0.415
Compound_8	O=C(C1CCN(C(=O)C1)C)N[C@@H]1CC[C@](CC1)(c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)OCc1c(F)cccc1F)S(=O)(=O)c1ccc(cc1)F	0.435	0.549	0.107	0.48	0.773	0.659	0.69	0.803	0.398	0.534	0.19
Compound_9	CC(=O)N1CCN(CC1)c1ccc(c(c1)F)CN(S(=O)(=O)c1ccc(cc1)C(C)C)C1CCC1	0.301	0.639	0.172	0.552	0.694	0.653	0.229	0.862	0.405	0.434	0.347
Compound_10	O=C(NS(=O)(=O)c1ccccc1F)C[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)C(F)(F)F)NC(=O)OC(C)(C)C	0.627	0.599	0.735	0.476	0.729	0.645	0.942	0.864	0.342	0.943	0.58
Compound_11	OCC(c1ncc(cn1)c1nccc(n1)[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F)O	0.554	0.663	0.715	0.58	0.673	0.646	0.929	0.517	0.407	0.006	0.442
Compound_12	COc1nc2ccc(cc2c(c1OCC(F)(F)F)C#N)[C@@](c1cncn1C)(c1ccc(nc1)C(F)(F)F)O	0.656	0.529	0.758	0.665	0.727	0.64	0.989	0.512	0.333	0.031	0.86
Compound_13	CN([C@@H]1CCN(C1)C(=O)C1CCc2c(C1)n(nc2C1=CCC(CC1)(C)C(=O)O)C(=O)c1c(Cl)cccc1C1(CC1)C(F)(F)F)C	0.793	0.808	0.204	0.291	0.792	0.762	0.844	0.834	0.349	0.966	0.368
Compound_14	CCn1nc(c(c1)S(=O)(=O)N1C[C@H](Oc2c1c(C)c(cc2)NC(=O)OC(C(F)(F)F)(C)C)CC(C(=O)O)(C)C)Cl	0.701	0.639	0.468	0.565	0.545	0.584	0.935	0.854	0.336	0.958	0.563
Compound_15	O=C1CN(CCN1CCS(=O)(=O)C)c1nccc(n1)[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.559	0.708	0.132	0.564	0.577	0.629	0.804	0.788	0.409	0.904	0.299
Compound_16	OC[C@@H](c1ccc(cc1)S(=O)(=O)CC)NC(=O)c1ccc2c(c1)nc(n2CC)C[C@@H]1CC[C@H](CC1)C(F)(F)F	0.37	0.634	0.078	0.487	0.688	0.74	0.967	0.186	0.382	0.282	0.308
Compound_17	C[C@H]1CC(CN1C(=O)c1nc(sc1c1c[nH]c(=NC(C)(C)C)cc1C(F)F)C(=O)N[C@H](C(O)(C)C)C)(F)F	0.649	0.438	0.298	0.44	0.417	0.66	0.18	0.765	0.293	0.128	0.185
Compound_18	O=C1CC2(N1)CCN(CC2)C(=O)C1CC[C@@]2([C@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccc(cc1)F	0.615	0.53	0.262	0.411	0.5	0.647	0.271	0.753	0.407	0.323	0.417
Compound_19	CC(N(C(=O)C1CCc2c(C1)n(nc2c1ccc(cc1F)C(=O)O)C(=O)c1c(Cl)cccc1C1(CC1)C(F)(F)F)C)c1cc[nH]n1	0.644	0.826	0.076	0.494	0.802	0.673	0.998	0.745	0.394	0.508	0.6
Compound_20	Clc1cccc(c1C(=O)c1cn(c2c1cccc2)c1ccc(c(c1F)F)C(=O)O)Cl	0.557	0.481	0.824	0.488	0.853	0.726	0.997	0.781	0.332	0.211	0.885
Compound_21	CC(Cc1ccc(cc1)c1onc(c1C1CC1)C(CC(=O)Nc1ccc(cc1Cl)C)CCC(=O)O)C	0.505	0.65	0.49	0.351	0.862	0.758	0.984	0.38	0.388	0.796	0.386
Compound_22	CC(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)OC(F)(F)F)NC(=O)OC(C(F)(F)F)(C)C	0.602	0.639	0.296	0.47	0.647	0.663	0.118	0.797	0.357	0.752	0.483
Compound_23	CC[C@@H](C(F)(F)F)N=c1[nH]cc(c(c1)C(F)(F)F)c1sc(nc1C(=O)N1C2CCC1CC2)C(=O)N[C@@H]1COC[C@H]1O	0.656	0.443	0.076	0.393	0.586	0.66	0.066	0.54	0.249	0.218	0.375
Compound_24	FC(c1cc(=NC(C2CC2)(C)C)[nH]cc1c1sc(nc1C(=O)N1C2CCC1CC2)C(=O)NCC(O)(C)C)F	0.647	0.542	0.077	0.363	0.51	0.654	0.178	0.782	0.366	0.182	0.223
Compound_25	OC(=O)c1ccc(c(c1)F)c1nn(c2c1NCCC2)C(=O)c1c(Cl)cccc1C1CC1	0.574	0.69	0.631	0.477	0.764	0.727	0.973	0.273	0.431	0.008	0.244
Compound_26	C[C@H]1CN(CC[C@H]1n1cnnc1)c1ccc(c(c1)F)CN1[C@@H](C)CC[C@@H](S1(=O)=O)c1ccccc1	0.622	0.717	0.228	0.579	0.295	0.855	0.941	0.855	0.391	0.284	0.313
Compound_27	O=C(c1cnn2c1nccc2)Nc1cc2cn(c(c2cc1C1CC1)O)C(C)C	0.662	0.71	0.088	0.533	0.691	0.652	0.989	0.457	0.393	0.108	0.22
Compound_28	O=C(c1ccc2c(c1)nc(n2Cc1cccc2c1OC(O2)(F)F)C1(F)CC1)NCC1CCN(CC1)S(=O)(=O)C	0.543	0.718	0.3	0.43	0.595	0.719	0.633	0.8	0.379	0.528	0.334
Compound_29	O=C(N1CC2(C1)CCCO2)C1CCc2c(C1)n(nc2C1=CCC(CC1)C(=O)O)C(=O)c1c(Cl)cccc1C1CC1	0.799	0.692	0.097	0.376	0.753	0.68	0.811	0.64	0.381	0.643	0.426
Compound_30	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNS(=O)(=O)c1ccc(s1)Cl)S(=O)(=O)c1ccc(cc1)F	0.677	0.589	0.62	0.457	0.732	0.674	0.56	0.933	0.381	0.135	0.63
Compound_31	FC(Oc1cc(ccc1c1n(C)nc(c1Cl)C(=O)NC[C@]1(O)CC[C@H](CC1)S(=O)(=O)C)CC(C(F)(F)F)(C)C)F	0.712	0.749	0.038	0.519	0.741	0.7	0.61	0.918	0.408	0.973	0.421
Compound_32	OC[C@@H](c1ccc(cn1)S(=O)(=O)CC)NC(=O)c1ccc2c(c1)cc(n2CC)Cc1ccc(cc1)C(F)(F)F	0.551	0.556	0.909	0.558	0.518	0.738	0.998	0.626	0.307	0.081	0.362
Compound_33	O=C(OC(C)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNC(=O)C1CC1)S(=O)(=O)c1ccc(cc1)F	0.65	0.579	0.591	0.569	0.45	0.621	0.06	0.816	0.364	0.926	0.533
Compound_34	COc1ccc2c(n1)CCN(C2C(=O)Nc1cc(F)c(c(c1)F)[Si](C)(C)C)C(=O)CCCC(=O)O	0.705	0.647	0.689	0.48	0.309	0.636	0.336	0.597	0.34	0.899	0.334
Compound_35	COc1cc(CCC(F)(F)F)ccc1c1n(CC)nc(c1C)C(=O)NC[C@@H]1CC[C@H](CC1)S(=O)(=O)C	0.732	0.639	0.554	0.579	0.567	0.712	0.689	0.966	0.455	0.917	0.304
Compound_36	CC(C(C(=O)N1CCC(CC1)c1cn(c2c1cc(cc2)NS(=O)(=O)c1ccc(cc1)F)C)C)C	0.542	0.798	0.605	0.48	0.158	0.758	0.986	0.471	0.244	0.671	0.422
Compound_37	CCS(=O)(=O)c1ccc(cc1)CC(=O)Nc1ccc(c(c1)F)OC(c1ccc(cc1Cl)Cl)(C)C	0.421	0.503	0.975	0.752	0.935	0.793	0.616	0.814	0.378	0.939	0.398
Compound_38	Fc1ccc(cc1)S(=O)(=O)Nc1ccc2c(c1)c(cn2C)[C@H]1CCN([C@H](C1)C)C(=O)C1CCCC1	0.529	0.719	0.605	0.501	0.191	0.788	0.983	0.636	0.231	0.258	0.314
Compound_39	COc1nc2ccc(cc2c(c1CN1CCC(CC1)(F)F)Cl)C(c1cnnn1C)(c1ccc(nc1C)C)O	0.636	0.71	0.635	0.283	0.742	0.635	0.99	0.203	0.528	0.905	0.344
Compound_40	CCc1sc(c(n1)S(=O)(=O)N1C[C@H](CCC(=O)O)Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)OC(C)C	0.688	0.597	0.445	0.653	0.546	0.647	0.812	0.95	0.349	0.886	0.459
Compound_41	OC(=O)CC1CCN(CC1)C(=O)c1ccc(c(c1Cl)Cn1ccc2c1ccc(c2)C(F)(F)F)Cl	0.716	0.583	0.779	0.462	0.761	0.75	0.99	0.668	0.413	0.438	0.357
Compound_42	Brc1cnc(o1)c1ccc2c(c1)n(nc2c1ccc(cc1F)C(=O)O)C(=O)c1c(Cl)cccc1C(F)(F)F	0.388	0.629	0.947	0.571	0.753	0.649	1.0	0.748	0.392	0.916	0.724
Compound_43	O=C(OC(C)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNS(=O)(=O)C1CC1)S(=O)(=O)c1ccc(c(c1)Cl)F	0.663	0.589	0.947	0.633	0.715	0.667	0.252	0.944	0.4	0.936	0.612
Compound_44	COc1nn2c(c1S(=O)(=O)N1C[C@H](CC(C(=O)O)C)Oc3c1cc(cc3)NC(=O)OC(C(F)(F)F)(C)C)CCCC2	0.716	0.668	0.262	0.543	0.615	0.643	0.959	0.871	0.359	0.935	0.428
Compound_45	OCC1Cc2ncc(cc2N(C1)S(=O)(=O)c1cccc(c1)C)NC(=O)c1c(Cl)cccc1Cl	0.601	0.49	0.571	0.581	0.442	0.752	0.558	0.117	0.398	0.064	0.369
Compound_46	CCS(=O)(=O)c1ccc(cc1)CC(=O)Nc1ccc(c(c1)Cl)c1ccccc1Cl	0.417	0.429	0.963	0.75	0.919	0.794	0.955	0.536	0.383	0.709	0.18
Compound_47	FC(Oc1cc(CCCC(F)(F)F)ccc1c1n(C)nc(c1Cl)C(=O)NC[C@]1(O)CC[C@H](C[C@H]1O)S(=O)(=O)C)F	0.74	0.709	0.025	0.542	0.708	0.67	0.576	0.918	0.401	0.678	0.428
Compound_48	OC[C@@H](Cn1nnc(c1)c1nccc(n1)[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F)O	0.591	0.684	0.377	0.631	0.683	0.64	0.956	0.22	0.397	0.012	0.423
Compound_49	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNS(=O)(=O)c1cnn(c1C)C(F)F)S(=O)(=O)c1ccc(cc1)F	0.69	0.554	0.765	0.493	0.714	0.636	0.724	0.872	0.359	0.768	0.616
Compound_50	Fc1cc(C(=O)O)c(cc1c1nn(c2c1c(F)ccc2)Cc1c(cccc1C(F)(F)F)C(C)C)O	0.433	0.69	0.61	0.415	0.968	0.746	0.999	0.951	0.395	0.014	0.582
Compound_51	O=C(c1nc(sc1c1c[nH]c(=N[C@H](C(F)(F)F)C2CC2)cc1C(F)F)C(=O)NC1CCS(=O)(=O)CC1)N1C2CCC1CC2	0.63	0.491	0.291	0.505	0.555	0.654	0.015	0.947	0.39	0.064	0.237
Compound_52	N#CC1(CC1)C[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cn(nc1Cl)CC)NC(=O)OC(C(F)(F)F)(C)C	0.696	0.596	0.674	0.666	0.641	0.631	0.904	0.958	0.398	0.998	0.657
Compound_53	CC[C@@H](C(F)(F)F)N=c1[nH]cc(c(c1)C(F)F)c1sc(nc1C(=O)N1CCC[C@@H]1C)C(=O)N[C@@H]1CC[C@H]1O	0.639	0.44	0.093	0.471	0.525	0.648	0.079	0.438	0.216	0.001	0.233
Compound_54	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNC(=O)C1CCN1)S(=O)(=O)c1ccc(cc1)F	0.675	0.579	0.492	0.427	0.689	0.576	0.125	0.192	0.342	0.095	0.549
Compound_55	Fc1ccc(cc1)S(=O)(=O)Nc1ccc2c(c1)c(cn2C)[C@@H]1CCN(C(C1)(C)C)C(=O)C1CCCC1	0.538	0.769	0.799	0.455	0.172	0.792	0.989	0.608	0.271	0.925	0.391
Compound_56	CC(CN(S(=O)(=O)Cc1ccccc1)Cc1ccc(cc1)N1CC2(C1)COCC2)C	0.37	0.659	0.817	0.482	0.588	0.828	0.977	0.93	0.358	0.309	0.576
Compound_57	CC(N(S(=O)(=O)Cc1ccccc1)Cc1ccc(cc1)N1CCN(CC1)C(=O)C)C	0.247	0.674	0.256	0.53	0.244	0.855	0.06	0.804	0.411	0.549	0.22
Compound_58	OC(=O)c1ccc(c(c1)F)c1nn(c2c1nccc2)C(=O)c1c(C)cccc1C1(CC1)C(F)(F)F	0.465	0.634	0.55	0.546	0.835	0.647	0.999	0.667	0.425	0.05	0.389
Compound_59	CC(CC(=O)N[C@@H]1CC[C@@]2([C@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccc(cc1)F)O	0.57	0.508	0.04	0.471	0.567	0.578	0.771	0.505	0.364	0.722	0.336
Compound_60	COc1nc2ccc(cc2c(c1CN1CCn2c(C1)nc(n2)C(F)(F)F)Cl)[C@@](c1cncn1C)(c1ccnc(c1)C(F)(F)F)O	0.657	0.681	0.307	0.373	0.719	0.658	0.992	0.665	0.446	0.067	0.423
Compound_61	CCn1nc(c(c1)S(=O)(=O)N1C[C@H](CNS(=O)(=O)C2CC2)Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)OC(F)F	0.698	0.619	0.381	0.609	0.651	0.635	0.702	0.93	0.391	0.923	0.491
Compound_62	CCCN(Cc1ccc(cc1)C(F)(F)F)Cc1ccc(cc1)NC(=O)Cc1ccc(cc1)S(=O)(=O)CC	0.324	0.41	0.286	0.296	0.839	0.676	0.979	0.932	0.394	0.171	0.213
Compound_63	CC(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cnc2n1cccc2)NC(=O)OC(C(F)(F)F)(C)C	0.685	0.579	0.042	0.572	0.538	0.636	0.622	0.904	0.364	0.874	0.486
Compound_64	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNC(=O)C1CCO1)S(=O)(=O)c1ccc(cc1)F	0.703	0.549	0.765	0.594	0.564	0.594	0.084	0.901	0.354	0.126	0.566
Compound_65	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNS(=O)(=O)CC1CCCCO1)S(=O)(=O)c1ccc(cc1)F	0.697	0.569	0.591	0.643	0.73	0.678	0.324	0.947	0.389	0.101	0.545
Compound_66	COc1cc(ccc1c1n(CC)nc(c1C(C)C)C(=O)NC[C@@H]1CC[C@H](CC1)S(=O)(=O)C)N[C@@H](C(F)(F)F)C	0.698	0.639	0.381	0.468	0.73	0.665	0.84	0.93	0.439	0.924	0.346
Compound_67	C[C@H]1CCCN1C(=O)c1nc(sc1c1c[nH]c(=NC2(C)CCC2)cc1C(F)F)C(=O)NCC(O)(C)C	0.639	0.498	0.092	0.412	0.457	0.649	0.143	0.78	0.313	0.096	0.246
Compound_68	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(CC(O2)C(=O)C(F)(F)F)S(=O)(=O)c1ccc(cc1)F	0.666	0.609	0.914	0.67	0.512	0.582	0.693	0.907	0.391	0.118	0.587
Compound_69	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNC(=O)c1c[nH]nc1)S(=O)(=O)c1ccc(c(c1)Cl)F	0.671	0.539	0.925	0.58	0.721	0.653	0.487	0.831	0.384	0.168	0.628
Compound_70	CCn1nc(c(c1c1ccc(cc1OC(F)F)C[C@H](C(F)(F)F)C)C)C(=O)NC[C@@]1(O)CC[C@@H](C[C@@H]1O)S(=O)(=O)C	0.719	0.709	0.152	0.574	0.673	0.656	0.623	0.956	0.399	0.905	0.409
Compound_71	CC[C@@H](C(F)(F)F)N=c1[nH]cc(c(c1)C(F)F)c1sc(nc1C(=O)N1CCC[C@@H]1C)C(=O)N[C@@H](CO)C	0.61	0.448	0.233	0.451	0.395	0.61	0.066	0.387	0.243	0.04	0.251
Compound_72	CCn1nc(c(c1c1ccc(cc1OC(F)F)CCC(F)(F)F)C)C(=O)NC[C@@H]1CC[C@H](CC1)S(=O)(=O)C	0.709	0.639	0.606	0.531	0.666	0.701	0.689	0.963	0.42	0.917	0.304
Compound_73	CC(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1ccc(cc1)F)NC(=O)OC(C(F)(F)F)c1ccccc1	0.66	0.438	0.917	0.645	0.76	0.631	0.173	0.628	0.34	0.25	0.511
Compound_74	N#Cc1cc(ccc1F)C(=O)Nc1cnc2c(c1C(F)(F)F)c(cn2C)C1CCN(CC1)C(=O)C1CCCC1	0.613	0.613	0.787	0.661	0.633	0.729	0.97	0.958	0.482	0.101	0.347
Compound_75	COc1ccc2c(c1)CCN(C2C(=O)Nc1cc(F)c(c(c1)F)[Si](C)(C)C)C(=O)CC(CC(=O)O)(O)C	0.555	0.761	0.314	0.482	0.462	0.638	0.898	0.739	0.351	0.892	0.242
Compound_76	CCn1nc(c(c1c1c[nH]c(=NC(CC(F)(F)F)(C)C)cc1OC(F)F)Cl)C(=O)NC[C@]1(O)CC[C@H](C[C@H]1O)S(=O)(=O)C	0.685	0.589	0.02	0.482	0.647	0.674	0.686	0.811	0.405	0.87	0.373
Compound_77	O=COC(Cc1nnc(s1)c1nc(c(s1)c1ccc(c(c1Cl)Cl)S(=O)(=O)N[C@H](C(F)(F)F)C)CC1CCC1)(C)C	0.616	0.595	0.302	0.512	0.705	0.652	0.985	0.921	0.395	0.988	0.506
Compound_78	CCn1nc(c(c1)S(=O)(=O)N1C[C@H](Oc2c1cc(cc2)N(C(C(F)(F)F)(C)C)C(=O)O)CC1(CC1)C(=O)N)Cl	0.705	0.626	0.277	0.353	0.538	0.609	0.757	0.128	0.399	0.989	0.535
Compound_79	FC1CN(C1)C1CN(C1)C(=O)C1CCc2c(C1)n(nc2C1=CCC(CC1)C(=O)O)C(=O)c1c(ccc(c1Cl)F)C1CC1	0.784	0.566	0.629	0.343	0.728	0.691	0.781	0.949	0.389	0.655	0.255
Compound_80	COc1nc2ccc(cc2c(c1CC(F)(F)F)Cl)C(c1cncn1C)(c1ccc(cc1)C#N)O	0.63	0.637	0.397	0.716	0.761	0.703	0.993	0.523	0.692	0.345	0.905
Compound_81	CC(Cc1onc(n1)c1onc(c1C1CC1)C(CC(=O)Nc1ccc(cc1Cl)C)CCC(=O)O)C	0.547	0.648	0.604	0.432	0.724	0.661	0.961	0.551	0.382	0.935	0.233
Compound_82	CC(=O)N=c1cc(n([nH]1)C(C1CC1)C)c1ccc(c(c1)N1CC2C(C1)C2)N(C(=O)c1c(F)cccc1Cl)C	0.689	0.644	0.134	0.519	0.699	0.712	0.826	0.393	0.488	0.386	0.097
Compound_83	CC(=O)N=c1cc(n([nH]1)C(C)C)c1ccc(c(c1)OCC1CCC1)N(C(=O)c1c(F)cccc1Cl)C	0.655	0.649	0.595	0.646	0.841	0.667	0.588	0.294	0.445	0.942	0.246
Compound_84	OC(=O)CC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1c(Cl)nc2n1ccs2)NC(=O)OC(C(F)(F)F)(C)C	0.645	0.629	0.262	0.634	0.579	0.661	0.964	0.917	0.311	0.55	0.505
Compound_85	O=C(Cc1ccc(cc1)S(=O)(=O)C)Nc1ccc(cc1)CCN1CCOc2c1cc(cc2)OC(C)C	0.524	0.7	0.776	0.547	0.746	0.54	0.889	0.501	0.395	0.982	0.187
Compound_86	Fc1ccc(cc1)S(=O)(=O)[C@@]12CC[C@H]([C@@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)N1CCC(=O)N1CC(O)(C)C	0.587	0.619	0.114	0.418	0.604	0.61	0.76	0.58	0.403	0.588	0.305
Compound_87	OC[C@@H](c1ccc(cc1)S(=O)(=O)CC)NC(=O)c1ccc2c(c1)cc(n2C1CC1)CN1CCC(CC1)C(F)(F)F	0.456	0.632	0.974	0.419	0.765	0.759	0.981	0.215	0.391	0.226	0.343
Compound_88	CC([C@@H]1N(Cc2ccc(c(n2)C)Cl)Cc2c1[nH]c(=NC(=O)Cc1ccc(cc1)S(=O)(=O)C)s2)C	0.462	0.589	0.055	0.26	0.384	0.7	0.032	0.511	0.397	0.154	0.304
Compound_89	O[C@H]1CC[C@@H](C1)NC(=O)c1nc(c(s1)c1c[nH]c(=N[C@H](C(F)(F)F)C)cc1C(F)F)C(=O)N1CCC[C@@H]1C	0.62	0.498	0.202	0.486	0.457	0.625	0.079	0.893	0.19	0.0	0.175
Compound_90	OC(=O)c1ccc(cc1)c1nn(c2c1cccc2)C(=O)c1c(Cl)cccc1C(F)(F)F	0.462	0.644	0.819	0.527	0.933	0.797	0.973	0.725	0.344	0.586	0.739
Compound_91	Fc1cc(C(=O)O)c(cc1c1nn(c2c1CCCC2)C(=O)c1c(Cl)cccc1C1CC1)O	0.614	0.571	0.242	0.434	0.917	0.774	0.969	0.748	0.433	0.563	0.579
Compound_92	NC(=O)Cn1ncc(c1)c1cccc(n1)[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.568	0.707	0.124	0.531	0.649	0.616	0.986	0.625	0.547	0.001	0.178
Compound_93	Fc1cccc(c1OCc1ccc2c(c1)N(CC2)S(=O)(=O)c1cccc(c1)C(F)(F)F)Cl	0.492	0.458	0.966	0.672	0.815	0.778	0.957	0.922	0.263	0.591	0.639
Compound_94	O=C(NS(=O)(=O)c1cccc(n1)C)C[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)C(F)(F)F)NC(=O)OC(C)(C)C	0.654	0.609	0.427	0.46	0.677	0.68	0.906	0.923	0.321	0.896	0.529
Compound_95	CCn1nc(c(c1c1c[nH]c(=NC(C(C(F)(F)F)(F)F)(C)C)cc1OC(F)F)Cl)C(=O)NC[C@]1(O)CC[C@H](CC1)S(=O)(=O)C	0.682	0.589	0.113	0.495	0.665	0.69	0.607	0.745	0.395	0.924	0.373
Compound_96	CCn1nc(c(c1c1ccc(cc1C)CC(C(F)(F)F)(C)C)Cl)C(=O)NC[C@@H]1CC[C@H](CC1)S(=O)(=O)C	0.667	0.719	0.148	0.523	0.659	0.78	0.95	0.98	0.459	0.849	0.298
Compound_97	N#Cc1cc(O)cc(c1)C(=O)Nc1cnc2c(c1C(F)(F)F)c(cn2C)C1CCN(CC1)C(=O)C(C(C)(C)C)C	0.626	0.717	0.205	0.669	0.62	0.773	0.973	0.945	0.511	0.629	0.647
Compound_98	Fc1cccc(c1c1nnc2c(c1)[C@@H]1CC[C@]2(C1(C)C)c1cccc(n1)c1c[nH]c(=NS(=O)(=O)C)cn1)F	0.669	0.629	0.641	0.663	0.571	0.608	0.844	0.537	0.418	0.595	0.541
Compound_99	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNS(=O)(=O)c1cn(nc1C(F)(F)F)C)S(=O)(=O)c1ccc(cc1)F	0.659	0.594	0.189	0.481	0.695	0.63	0.724	0.855	0.359	0.896	0.634
Compound_100	OC(=O)c1ccc(cc1)n1cc(c2c1c(F)ccc2)C(=O)c1c(Cl)cccc1C(F)(F)F	0.452	0.477	0.363	0.436	0.854	0.67	0.997	0.942	0.263	0.138	0.946
Compound_101	OC(=O)C(Cc1nnc(o1)c1nc(c(s1)c1ccc(c(c1Cl)Cl)C(C(F)(F)F)(C(F)(F)F)O)CN1CCCC(C1)(F)F)(C)C	0.592	0.615	0.734	0.43	0.688	0.648	0.978	0.735	0.363	0.349	0.349
Compound_102	CCc1ccc(cc1)N(S(=O)(=O)c1ccc(c(c1)S(=O)(=N)C)NCC1CSC1)CC(C)C	0.29	0.458	0.618	0.326	0.528	0.61	0.454	0.147	0.213	0.237	0.444
Compound_103	CCOc1ccccc1CN1CCc2c1ccc(c2)NC(=O)C1N(CCc2c1ccc(n2)OC)C(=O)CCCC(=O)O	0.684	0.639	0.092	0.48	0.481	0.79	0.634	0.747	0.312	0.573	0.734
Compound_104	O=COC(Cc1nnc(o1)c1nc(c(s1)c1cnc(c2c1cccc2)S(=O)(=O)N[C@H](C(F)(F)F)C)CC1CCCCC1)(C)C	0.624	0.619	0.65	0.511	0.672	0.653	0.997	0.902	0.364	0.973	0.392
Compound_105	COc1nc2ccc(cc2c(c1OCC1CC1(F)F)Cl)C(c1cnnn1C)(c1ccc(nc1C)C)O	0.605	0.744	0.471	0.619	0.695	0.64	0.992	0.576	0.501	0.746	0.625
Compound_106	CC[C@@H](C(F)(F)F)N=c1[nH]cc(c(c1)C(F)F)c1sc(nc1C(=O)N1CCC[C@@H]1C)C(=O)N1CC2CC(C1)O2	0.674	0.537	0.341	0.597	0.45	0.548	0.108	0.642	0.338	0.052	0.252
Compound_107	CCN(C(=O)c1ccc(cc1)c1n[nH]cn1)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.445	0.771	0.369	0.561	0.641	0.656	0.975	0.833	0.499	0.965	0.178
Compound_108	COCCS(=O)(=O)c1ccc2c(c1)CN(C2C(=O)Nc1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)O)C(=O)CO	0.419	0.618	0.571	0.629	0.646	0.608	0.738	0.31	0.365	0.072	0.315
Compound_109	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CC(NS(=O)(=O)C1CC1)(C)C)S(=O)(=O)c1ccc(c(c1)Cl)F	0.671	0.669	0.956	0.683	0.738	0.666	0.946	0.943	0.401	0.916	0.578
Compound_110	Fc1ccc(cc1)S(=O)(=O)[C@@]12CC[C@H]([C@@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)NC1CCN(CC1)S(=O)(=O)C	0.603	0.616	0.209	0.37	0.565	0.57	0.682	0.772	0.402	0.24	0.394
Compound_111	O=C(C[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)C(F)(F)F)NC(=O)OC(C)(C)C)NOCc1cccnc1	0.624	0.619	0.824	0.643	0.5	0.642	0.872	0.851	0.368	0.974	0.611
Compound_112	COc1nc2ccc(cc2c(c1CN1CC(C1)C(F)(F)F)Cl)[C@@](c1cnc(n1C)C)(c1cnnn1C)O	0.675	0.599	0.335	0.257	0.718	0.641	0.996	0.216	0.368	0.987	0.52
Compound_113	CCS(=O)(=O)c1ccc(cc1)CC(=O)N=c1sc2c([nH]1)[C@@H](N(C2)Cc1ccc(cc1)c1nnn(n1)C)C(C)C	0.475	0.569	0.052	0.304	0.543	0.662	0.854	0.542	0.345	0.37	0.385
Compound_114	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CC(C(=O)O)C)S(=O)(=O)c1cccc(c1)C(F)(F)F	0.663	0.659	0.266	0.647	0.575	0.606	0.917	0.92	0.321	0.855	0.55
Compound_115	OC(=O)c1ccc(c(c1)F)c1nn(c2c1S(=O)CCC2)C(=O)c1c(Cl)cccc1C1(CC1)C(F)(F)F	0.646	0.582	0.252	0.556	0.88	0.713	0.76	0.885	0.41	0.052	0.424
Compound_116	COc1ccc(cc1S(=O)(=O)N1C[C@H](CCC(=O)O)Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)C	0.701	0.699	0.362	0.66	0.559	0.595	0.92	0.719	0.303	0.911	0.514
Compound_117	Fc1cc(ccc1CN(S(=O)(=O)Cc1ccccc1)CC(F)(F)F)N1CCN(CC1)S(=O)(=O)C	0.429	0.653	0.189	0.6	0.84	0.845	0.775	0.951	0.405	0.364	0.404
Compound_118	BrN[C@@H]1C[C@@H](CC[C@@]1(O)CNC(=O)c1nn(c(c1Cl)c1ccc(cc1OC(F)F)CC(C(F)(F)F)(C)C)CC)S(=O)(=O)C	0.703	0.719	0.055	0.532	0.726	0.687	0.708	0.944	0.405	0.994	0.566
Compound_119	OC(=O)C(C[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)C(F)(F)F)c1cccc(c1F)Cl)(C)C	0.67	0.689	0.896	0.505	0.765	0.645	0.762	0.779	0.281	0.396	0.482
Compound_120	COc1nn(c(c1S(=O)(=O)N1C[C@@H](Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)CC(NC(=O)C)(C)C)C)CC	0.717	0.709	0.521	0.618	0.557	0.66	0.791	0.889	0.384	0.925	0.453
Compound_121	CCN(C(=O)c1c[nH]nc1n1cnnn1)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.505	0.751	0.181	0.557	0.691	0.653	0.901	0.559	0.468	0.978	0.214
Compound_122	CCn1nc(c(c1)S(=O)(=O)N1C[C@H](CC(=O)C(O)O)Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)Cl	0.686	0.596	0.653	0.622	0.463	0.581	0.73	0.739	0.337	0.813	0.563
Compound_123	CC(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1ccc(cc1)F)NC(=O)O[C@H](C(C(F)(F)F)(F)F)C	0.655	0.478	0.974	0.627	0.636	0.599	0.141	0.772	0.365	0.184	0.5
Compound_124	Clc1cccc(c1C(=O)c1nn(c2c1cccc2)c1ccc(cc1)C(=O)O)Cl	0.567	0.568	0.916	0.524	0.948	0.798	0.99	0.812	0.276	0.354	0.872
Compound_125	CC(CN(S(=O)(=O)Cc1ccccc1)Cc1ccc(cc1)N1CCC2(C1)CCCO2)C	0.448	0.689	0.133	0.521	0.513	0.862	0.94	0.896	0.361	0.331	0.445
Compound_126	C[C@H]1CCCN1C(=O)c1nc(sc1c1c[nH]c(=NC(C)(C)C)cc1C(F)(F)F)C(=O)NCC(C(F)(F)F)O	0.617	0.518	0.024	0.346	0.382	0.623	0.062	0.815	0.21	0.086	0.233
Compound_127	CCS(=O)(=O)c1ccc(nc1)CNC(=O)c1ccc(cc1)CCN1CCOc2c1cc(cc2)CC(C)C	0.626	0.626	0.3	0.401	0.422	0.751	0.957	0.958	0.355	0.821	0.178
Compound_128	CNS(=O)(=O)c1ccc(cc1)CNC(=O)c1ccc2c(c1)nc(n2Cc1cccc2c1OC(O2)(F)F)C1(F)CC1	0.522	0.539	0.042	0.322	0.706	0.68	0.91	0.573	0.238	0.684	0.388
Compound_129	CCS(=O)(=O)c1ccc(cc1)[C@@H](NC(=O)c1ccc2c(c1)nc(n2C1CC1)C[C@@H]1CC[C@H](CC1)C(F)(F)F)COC(=O)N	0.451	0.606	0.198	0.336	0.728	0.727	0.989	0.758	0.396	0.875	0.409
Compound_130	FC([C@H]1CC[C@@H](S(=O)(=O)N1Cc1cc(F)c(cc1F)N1CCC(CC1)n1cnnc1)c1ccccc1)F	0.642	0.556	0.347	0.597	0.573	0.8	0.967	0.88	0.395	0.196	0.337
Compound_131	OC(=O)CC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cncc(c1)C)NC(=O)OC(C(F)(F)F)(C)C	0.658	0.659	0.5	0.651	0.367	0.549	0.883	0.88	0.349	0.885	0.549
Compound_132	CCS(=O)(=O)c1ccc(cc1)CC(=O)Nc1ccc(cc1)CCN1CCCc2c1cc(cc2)C1CC1	0.402	0.58	0.097	0.455	0.761	0.605	0.969	0.388	0.401	0.079	0.099
Compound_133	CCn1nc(c(c1c1c[nH]c(=NC(CC(F)(F)F)(C)C)cc1OC(F)F)C)C(=O)NC[C@@H]1CC[C@H](CC1)S(=O)(=O)C	0.646	0.609	0.084	0.435	0.568	0.687	0.342	0.826	0.418	0.841	0.308
Compound_134	C[C@H]1CC[C@@H](S(=O)(=O)N1Cc1cc(F)c(cc1F)N1C[C@@H]2[C@H](C1)C2n1cnnc1)c1ccccc1	0.609	0.656	0.612	0.617	0.5	0.806	0.958	0.855	0.395	0.185	0.321
Compound_135	OC(=O)C1CCN(C1)C(=O)C1CC[C@@]2([C@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccc(cc1)F	0.576	0.578	0.422	0.383	0.687	0.651	0.661	0.856	0.4	0.273	0.336
Compound_136	OC(=O)CC1CCN(CC1)C(=O)c1ccc(c(c1Cl)C(=O)n1nc(c2c1c(C)cc(c2)C(F)(F)F)C)Cl	0.655	0.685	0.712	0.361	0.81	0.714	0.986	0.968	0.425	0.448	0.222
Compound_137	N#Cc1cccc(c1)C(=O)Nc1cnc2c(c1C(F)(F)F)c(cn2C)C1CCN(CC1)C(=O)CC1CCCCC1	0.638	0.643	0.386	0.63	0.477	0.753	0.977	0.949	0.562	0.076	0.536
Compound_138	OC(=O)c1ccc(c(c1)F)c1nn(c2c1ccc(c2)N1CCNC1=O)C(=O)c1c(Cl)cccc1C(F)(F)F	0.505	0.643	0.367	0.436	0.905	0.738	0.995	0.84	0.377	0.115	0.517
Compound_139	O=COC(Cc1nnc(o1)c1nc(c(s1)c1ccc(c(c1Cl)Cl)S(=O)(=O)N[C@H](C(F)(F)F)CC)CC(OC)(C)C)(C)C	0.534	0.476	0.324	0.459	0.707	0.652	0.952	0.95	0.39	0.955	0.436
Compound_140	O=C1CCC(CN1)C(=O)N[C@@H]1CC[C@@]2([C@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccc(cc1)F	0.671	0.478	0.134	0.363	0.537	0.56	0.211	0.696	0.402	0.028	0.289
Compound_141	CC(CN(S(=O)(=O)Cc1ccccc1)Cc1ccc(cc1)c1ccc(cc1)S(=O)(=O)C)C	0.194	0.546	0.875	0.632	0.669	0.758	0.337	0.594	0.402	0.174	0.215
Compound_142	C=CCC1C(=O)C(=C[C@@]2([C@@H]1CCc1c2nc(nc1c1ccccc1F)c1ccnc(c1)C1CC1)C)C#N	0.563	0.657	0.739	0.747	0.773	0.687	0.524	0.969	0.419	0.586	0.815
Compound_143	Fc1ccc(cc1)S(=O)(=O)Nc1ccc2c(c1)c(cn2C)[C@@H]1CCN([C@H](C1)C)C(=O)C1CCCC1	0.529	0.719	0.605	0.501	0.191	0.788	0.983	0.636	0.231	0.258	0.314
Compound_144	Clc1ccc(c(c1Cc1cc2c(n1C)cc(cc2C)C(F)(F)F)Cl)C(=O)N1CCC(CC1)S(=O)(=O)C	0.551	0.758	0.743	0.59	0.757	0.74	0.958	0.968	0.419	0.896	0.279
Compound_145	OC[C@@H](c1ccc(cc1)S(=O)(=O)CC)NC(=O)c1ccc2c(c1)cc(n2CC)Cc1ccc(cn1)C(F)(F)F	0.402	0.566	0.96	0.515	0.596	0.695	0.998	0.574	0.376	0.111	0.384
Compound_146	CCS(=O)(=O)c1ccc(cc1)CNC(=O)c1ccc2c(c1)nc(n2CC(C)C)O[C@@H]1CC[C@H](CC1)C(F)(F)F	0.486	0.747	0.042	0.466	0.679	0.752	0.572	0.651	0.382	0.766	0.322
Compound_147	O=C(C1CCc2c(C1)n(nc2c1ccc(cc1F)C(=O)O)C(=O)c1c(Cl)cccc1C1(CC1)C(F)(F)F)N1CCc2c(C1)cn[nH]2	0.654	0.75	0.03	0.549	0.809	0.669	0.992	0.688	0.397	0.306	0.413
Compound_148	O[C@@H]1C[C@H](O)CN(C1)C(=O)c1nc(c(s1)c1ccc(cc1OC(C)C)C(C(F)(F)F)(C(F)(F)F)O)C(=O)N1CC(C[C@@H]1C)(F)F	0.743	0.649	0.553	0.788	0.562	0.704	0.517	0.776	0.314	0.947	0.637
Compound_149	N#CCC(=N)/C=C\C(=N)C(=O)N(C[C@@]12CC[C@H](C2(C)C)/C(=C/C(=N)c2c(F)cccc2F)/C1=N)CC	0.649	0.599	0.353	0.645	0.416	0.46	0.315	0.926	0.451	0.621	0.338
Compound_150	CC(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)C)NC(=O)OC(C(F)(F)F)(C)C	0.632	0.569	0.226	0.518	0.443	0.646	0.166	0.867	0.382	0.757	0.533
Compound_151	C[C@H]1CN(CCC1C(=O)O)C(=O)c1ccc(c(c1Cl)C(=O)c1cc2c(n1C)cc(cc2C)C(F)(F)F)Cl	0.603	0.718	0.803	0.402	0.697	0.593	0.984	0.917	0.404	0.796	0.433
Compound_152	COc1nc2ccc(cc2c(c1CN1CCC(CC1)C(F)(F)F)Cl)[C@@](c1cnc(n1C)C)(c1ccnc(c1)C(F)(F)F)O	0.662	0.656	0.409	0.263	0.817	0.668	0.994	0.281	0.441	0.918	0.494
Compound_153	COc1nn(c(c1S(=O)(=O)N1C[C@H](CNC(=O)C)Oc2c1cc(cc2)NC(=O)OC(C)(C)C)C)C	0.705	0.679	0.079	0.532	0.46	0.645	0.227	0.488	0.402	0.792	0.392
Compound_154	CCN(S(=O)(=O)c1cnc(n1C)C)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.493	0.619	0.045	0.647	0.612	0.63	0.981	0.702	0.409	0.983	0.402
Compound_155	C[C@H]1CCCCN1C(=O)c1nc(sc1c1cnc(cc1C)C(C(F)(F)F)(C(F)(F)F)O)C(=O)NCC(O)(C)C	0.61	0.623	0.078	0.494	0.399	0.671	0.39	0.824	0.362	0.908	0.598
Compound_156	Fc1ccc(cc1)S(=O)(=O)[C@@]1(CC[C@@H](CC1)N1CCOCC1)c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)OCc1c(F)cccc1F	0.376	0.578	0.059	0.307	0.871	0.628	0.88	0.444	0.386	0.702	0.398
Compound_157	CCN(C(=O)c1nc(sc1c1ccc(c(c1Cl)Cl)C(C(F)(F)F)(C(F)(F)F)O)C(=O)N1CC(C1)(O)C(O)(C)C)CC	0.594	0.582	0.201	0.799	0.606	0.601	0.743	0.897	0.31	0.93	0.334
Compound_158	OCCOc1nn(cc1S(=O)(=O)N1C[C@H](CNC(=O)C(O)(C)C)Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)CC	0.686	0.708	0.463	0.501	0.477	0.607	0.277	0.622	0.342	0.618	0.453
Compound_159	F[C@@H]1CN(CC[C@@H]1n1cnnc1)c1cc(F)c(cc1F)CN1[C@@H](C)CC[C@@H](S1(=O)=O)c1ccccc1	0.62	0.637	0.393	0.625	0.345	0.803	0.97	0.924	0.392	0.216	0.312
Compound_160	Clc1ccc(cc1C(=O)Nc1ccccc1F)N(=O)=O	0.982	0.663	0.975	0.766	0.587	0.891	0.992	0.977	0.446	0.998	0.479
Compound_161	CCS(=O)(=O)c1ccc(cc1)CC(=O)Nc1sc(c(c1)c1cccc(c1)Cl)C(=O)c1cccc(c1)Cl	0.549	0.488	0.556	0.601	0.644	0.81	0.988	0.436	0.402	0.896	0.182
Compound_162	C[C@H]1CCCN1C(=O)c1nc(sc1c1c[nH]c(=NC(C)(C)C)cc1C(F)(F)F)C(=O)NC1CCOCC1	0.605	0.599	0.088	0.412	0.264	0.685	0.032	0.833	0.378	0.717	0.288
Compound_163	N#C[C@@H](c1coc(n1)c1cncc(n1)[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F)C	0.568	0.685	0.403	0.644	0.688	0.653	0.983	0.595	0.547	0.53	0.645
Compound_164	CCN(C(=O)Cn1cncn1)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.446	0.733	0.373	0.682	0.506	0.602	0.856	0.356	0.451	0.9	0.103
Compound_165	OC(=O)C1CCC(CC1)C(=O)N1CC[C@@]2([C@H]1CN(C)c1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccc(cc1)F	0.656	0.696	0.32	0.427	0.759	0.356	0.904	0.881	0.384	0.236	0.261
Compound_166	NC(=O)c1ccc(c(c1)c1cnc(c(c1)OCC1CCC1)N(C(=O)c1c(F)cccc1Cl)C)Cl	0.702	0.622	0.646	0.398	0.675	0.651	0.858	0.715	0.442	0.349	0.409
Compound_167	CN([C@@H]1CCN(C1)C(=O)C1CCc2c(C1)n(nc2C1=CCC(CC1)C(=O)O)C(=O)c1c(Cl)cccc1C1(CC1)C(F)(F)F)C	0.793	0.746	0.068	0.292	0.792	0.762	0.844	0.806	0.333	0.685	0.383
Compound_168	CC(=O)N[C@@H]1C[C@@H](C1)NC(=O)C1CC[C@@]2([C@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccc(cc1)F	0.582	0.507	0.05	0.385	0.693	0.653	0.684	0.784	0.406	0.811	0.401
Compound_169	C[C@@H]1Oc2ncc(cc2N(C1)S(=O)(=O)c1cccc(c1)C)NC(=O)C(c1ccc(cc1)F)C	0.619	0.591	0.761	0.453	0.157	0.654	0.519	0.525	0.433	0.899	0.5
Compound_170	CCS(=O)(=O)c1ccc(nc1)C(C(=O)Nc1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)O)NC(=O)C	0.387	0.429	0.393	0.552	0.608	0.451	0.131	0.475	0.317	0.142	0.361
Compound_171	N#Cc1ccc(cc1Cl)NC(=O)CC(CC(=O)Nc1ccc2c(c1)c(=O)n(c(=O)n2CC)CC)C	0.577	0.559	0.826	0.631	0.856	0.799	0.954	0.754	0.742	0.959	0.792
Compound_172	CC(CN(S(=O)(=O)Cc1ccccc1)Cc1ccc(cc1)N1CCN(CC1)C(=O)C1CC1)C	0.223	0.656	0.577	0.54	0.382	0.873	0.313	0.838	0.41	0.059	0.226
Compound_173	O=C(OC(C)(C)C)Nc1cccc(c1)COC(C(F)(F)F)(C(F)(F)F)c1ccc(cc1)C1(CCCC1)S(=O)(=O)c1ccc(cc1)F	0.75	0.605	0.367	0.647	0.934	0.89	0.72	0.897	0.395	0.734	0.447
Compound_174	OC(=O)CC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)S(F)(F)(F)(F)F)NC(=O)OC(C(F)(F)F)(C)C	0.601	0.639	0.27	0.644	0.619	0.634	0.776	0.84	0.302	0.103	0.571
Compound_175	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNC(=O)C1(N)CCCC1)S(=O)(=O)c1ccc(cc1)F	0.677	0.649	0.645	0.518	0.623	0.685	0.044	0.797	0.344	0.115	0.461
Compound_176	COc1cc(CCC(F)(F)F)ccc1c1n(CC)nc(c1Cl)C(=O)NC[C@]1(O)CC[C@H](CC1)S(=O)(=O)C	0.724	0.679	0.129	0.561	0.677	0.697	0.61	0.974	0.435	0.99	0.435
Compound_177	Fc1cccc(c1c1nnc2c(c1)[C@@H]1CC[C@]2(C1(C)C)c1cncc(n1)c1occ(n1)CNS(=O)(=O)C)F	0.637	0.708	0.745	0.478	0.681	0.652	0.994	0.853	0.419	0.598	0.55
Compound_178	O=C(OC(C)(C)C)NC1Cc2ncc(cc2N(C1)S(=O)(=O)c1cccc(c1)C(F)(F)F)NC(=O)c1c(Cl)cccc1Cl	0.664	0.549	0.294	0.555	0.584	0.761	0.923	0.895	0.384	0.73	0.601
Compound_179	COc1cc(ccc1F)S(=O)(=O)N1C[C@H](CCC(=O)O)Oc2c1cc(cc2)NC(=O)O[C@@H](C(F)(F)F)C(C)(C)C	0.67	0.669	0.928	0.667	0.674	0.65	0.776	0.801	0.328	0.946	0.523
Compound_180	CNC(=O)C[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)C(F)(F)F)NC(=O)OCC(C)(C)C	0.634	0.659	0.844	0.611	0.472	0.613	0.291	0.94	0.35	0.946	0.541
Compound_181	O=C(c1ccc(c(c1C)Cc1cc2c(n1C)cc(cc2C)C(F)(F)F)C)N1CCOCC1	0.435	0.714	0.762	0.511	0.715	0.785	0.992	0.706	0.45	0.596	0.463
Compound_182	O=C(C1CC[C@@]2([C@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccc(cc1)F)N[C@H]1CC[C@@H](C1)C(=O)O	0.547	0.478	0.175	0.377	0.599	0.649	0.637	0.768	0.394	0.415	0.33
Compound_183	O=C(C1CC[C@@]2([C@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccc(cc1)F)N[C@@H]1C[C@H](C1)C(=O)O	0.545	0.468	0.175	0.342	0.767	0.652	0.721	0.773	0.399	0.415	0.399
Compound_184	O[C@@H]1C[C@H](C1)NC(=O)c1nc(c(s1)c1c[nH]c(=NC2(C)CCC2)cc1C(F)F)C(=O)N1C2CCC1CC2	0.644	0.478	0.109	0.429	0.668	0.652	0.101	0.84	0.282	0.006	0.2
Compound_185	OCCOc1nn2c(c1S(=O)(=O)N1C[C@H](CNC(=O)C)Oc3c1cc(cc3)NC(=O)OC(C(F)(F)F)(C)C)cccc2	0.69	0.709	0.023	0.533	0.601	0.641	0.75	0.619	0.368	0.402	0.444
Compound_186	CC(=O)Nc1cc(C)c2c(c1)n(C)c(c2)Cc1c(Cl)ccc(c1Cl)C(=O)N1CCOCC1	0.636	0.709	0.449	0.593	0.852	0.747	0.992	0.492	0.432	0.819	0.435
Compound_187	Cc1nccc(c1)C(c1cncn1C)(c1ccc2c(c1)c(Cl)c(c(n2)Cl)c1ccccc1)O	0.455	0.716	0.289	0.729	0.719	0.674	0.918	0.841	0.591	0.244	0.863
Compound_188	OC(=O)C1CC(C1)NC(=O)c1nc(c(s1)c1cc(cc(c1)C(C(F)(F)F)(C(F)(F)F)O)C(C)(C)C)CC1CCCCC1	0.546	0.678	0.048	0.543	0.671	0.656	0.675	0.95	0.39	0.885	0.293
Compound_189	CC(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cc(cnc1Cl)C(F)(F)F)NC(=O)OC(C)(C)C	0.647	0.549	0.161	0.553	0.47	0.618	0.427	0.928	0.398	0.899	0.581
Compound_190	OCC1CCc2c(C1)n(nc2C1=CCC(CC1)C(=O)O)C(=O)c1c(ccc(c1Cl)F)C1CC1	0.773	0.677	0.557	0.383	0.793	0.767	0.444	0.788	0.389	0.351	0.417
Compound_191	CC(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1ccc(cc1)F)NC(=O)OC(C(c1ccccc1)(C)C)C(F)(F)F	0.658	0.549	0.778	0.639	0.791	0.646	0.238	0.811	0.367	0.805	0.532
Compound_192	CC(=O)N1CCN(CC1)c1ccc(c(c1)F)CN(S(=O)(=O)c1cccc(c1Cl)Cl)C1CCC1	0.387	0.629	0.433	0.568	0.696	0.655	0.11	0.991	0.406	0.268	0.368
Compound_193	O=C(N1CCC(C1)(C)O)C1CCc2c(C1)n(nc2C1=CCC(CC1)C(=O)O)C(=O)c1c(Cl)cccc1C1CC1	0.779	0.808	0.228	0.402	0.738	0.741	0.732	0.807	0.363	0.79	0.491
Compound_194	N#CCC[C@]1(C)COc2c(C1)cc(c(c2)N1CCOCC1)NC(=O)c1cnn2c1nccc2	0.607	0.706	0.028	0.5	0.55	0.672	0.617	0.782	0.47	0.088	0.601
Compound_195	OC1CN(C1)c1ccc(cn1)c1cncc(n1)[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.611	0.607	0.332	0.598	0.672	0.644	0.936	0.848	0.395	0.032	0.362
Compound_196	CCc1ccc(cc1)N(S(=O)(=O)c1ccc(c(c1)S(=O)(=N)C)NC[C@@H]1[C@@H]2[C@H]1COC2)CC(C)C	0.366	0.518	0.618	0.336	0.539	0.621	0.471	0.147	0.236	0.788	0.493
Compound_197	CCC1N(C[C@@H]2CC[C@H](CC2)C(F)(F)F)Cc2c1ccc(c2)C(=O)N[C@H](c1ccc(cc1)S(=O)(=O)CC)COC(=O)N	0.533	0.606	0.023	0.216	0.506	0.668	0.949	0.505	0.398	0.509	0.395
Compound_198	Fc1cccc(c1c1nnc2c(c1)[C@@H]1CC[C@]2(C1(C)C)c1cncc(n1)c1ccn(n1)CCNS(=O)(=O)C)F	0.606	0.728	0.141	0.397	0.652	0.632	0.988	0.861	0.41	0.776	0.624
Compound_199	CCS(=O)(=O)c1ccc(cc1)CNC(=O)c1cnc2c(c1)[C@@H](C)N(C2C(C)C)Cc1ccc(cc1)C(F)(F)F	0.432	0.599	0.151	0.264	0.562	0.583	0.961	0.968	0.393	0.241	0.306
Compound_200	O=COC(Cc1nnc(o1)c1nc(c(s1)c1ccc(cc1OC(F)(F)F)S(=O)(=O)N[C@H](C(F)(F)F)CC)CC1CCC1)(C)C	0.566	0.549	0.587	0.453	0.69	0.652	0.945	0.736	0.388	0.943	0.429
Compound_201	CC[C@@H](C(F)(F)F)N=c1[nH]cc(c(c1)C(F)F)c1sc(nc1C(=O)N1CC(C[C@@H]1C)(F)F)C(=O)N[C@@H](CO)C	0.647	0.418	0.442	0.455	0.395	0.61	0.066	0.278	0.231	0.078	0.209
Compound_202	C[C@H]1CCCN1C(=O)c1nc(sc1c1c[nH]c(=NC(C(F)(F)F)C)cc1C(F)F)C(=O)N[C@H](C(O)(C)C)C	0.613	0.458	0.224	0.463	0.429	0.613	0.039	0.863	0.234	0.069	0.221
Compound_203	CCn1nc(c(c1c1ccc(cc1OC(F)F)CC(C(F)(F)F)(C)C)Cl)C(=O)NC[C@@H]1CC[C@@H](CN1)S(=O)(=O)C	0.676	0.749	0.013	0.403	0.678	0.746	0.726	0.571	0.411	0.997	0.381
Compound_204	FC(CN(C(=O)c1ccc(=O)[nH]n1)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F)F	0.505	0.703	0.124	0.523	0.604	0.569	0.109	0.429	0.511	0.044	0.098
Compound_205	N#Cc1ccc(cc1)[C@@H](N1Cc2c([C@@H]1C(C)C)[nH]c(=NC(=O)Cc1ccc(cc1)S(=O)(=O)C)s2)C	0.413	0.579	0.059	0.284	0.391	0.66	0.312	0.148	0.389	0.477	0.402
Compound_206	C[C@@H]1Oc2ncc(cc2N(C1)S(=O)(=O)c1cccc(c1)C)NC(=O)C(c1ccccc1C)C	0.589	0.576	0.355	0.4	0.114	0.648	0.514	0.35	0.38	0.747	0.306
Compound_207	CCCn1nc(c(c1c1ccc(cc1OC)C[C@@H](C(F)(F)F)C)Cl)C(=O)NC[C@@H]1CC[C@H](CC1)S(=O)(=O)C	0.7	0.659	0.24	0.568	0.646	0.749	0.677	0.959	0.453	0.973	0.314
Compound_208	CCN(C(=O)c1ccc(cc1)S(=O)(=O)NC)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.409	0.789	0.014	0.459	0.596	0.615	0.495	0.741	0.361	0.922	0.393
Compound_209	Fc1ccc(cc1)S(=O)(=O)[C@]1(CC[C@H](C1)NC(=O)N1CCOCC1)c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)F	0.396	0.514	0.206	0.407	0.644	0.561	0.458	0.593	0.398	0.534	0.315
Compound_210	O=C(NS(=O)(=O)c1ccccn1)C[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)C(F)(F)F)NC(=O)OC(C)(C)C	0.641	0.609	0.153	0.483	0.566	0.649	0.918	0.922	0.334	0.896	0.529
Compound_211	CC(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cnc2n1cccc2)NC(=O)OC(C)(C)C	0.672	0.609	0.029	0.543	0.477	0.638	0.223	0.882	0.378	0.861	0.373
Compound_212	CCN(C(=O)C1CC[C@](C1)(c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccc(cc1)F)CC	0.429	0.556	0.368	0.587	0.424	0.646	0.783	0.777	0.352	0.88	0.205
Compound_213	Oc1n(cc2c1cc(N1CCN(CC1)CC(F)(F)C)c(c2)NC(=O)c1cnn2c1nccc2)C[C@H](C(O)(C)C)F	0.595	0.797	0.115	0.431	0.67	0.65	0.994	0.683	0.409	0.733	0.352
Compound_214	O=C(OC(C)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNC(=O)C(C)C)S(=O)(=O)c1ccc(cc1)F	0.638	0.619	0.579	0.578	0.372	0.639	0.043	0.798	0.348	0.793	0.541
Compound_215	CCn1nc(c(c1)S(=O)(=O)N1C[C@H](CNC(=O)C)Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)OC(C)C	0.695	0.618	0.366	0.539	0.5	0.612	0.403	0.921	0.388	0.703	0.465
Compound_216	OC[C@@H](c1ccc(cc1)S(=O)(=O)C)NC(=O)c1ccc2c(c1)nc(n2Cc1cccc2c1OC(O2)(F)F)C(F)F	0.415	0.426	0.511	0.367	0.729	0.676	0.987	0.357	0.383	0.347	0.367
Compound_217	CC(=O)C(NC1Cc2ncc(cc2N(C1)S(=O)(=O)c1cccc(c1)C)NC(=O)c1c(Cl)cccc1Cl)O	0.662	0.561	0.274	0.421	0.443	0.744	0.602	0.314	0.394	0.184	0.301
Compound_218	CCOc1nn(cc1S(=O)(=O)N1C[C@H](CNC(=O)C(O)(C)C)Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)CC(F)F	0.717	0.678	0.336	0.519	0.566	0.615	0.315	0.529	0.331	0.636	0.489
Compound_219	CCN(S(=O)(=O)c1ccc(cc1)S(=O)(=O)C)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.428	0.739	0.089	0.638	0.583	0.646	0.769	0.467	0.402	0.963	0.423
Compound_220	OC[C@@H](c1ccc(cn1)S(=O)(=O)CC)NC(=O)c1ccc2c(c1)cc(n2CC)C[C@@H]1CC[C@H](CC1)C(F)(F)F	0.59	0.624	0.804	0.586	0.48	0.772	0.977	0.331	0.293	0.178	0.332
Compound_221	COc1cc(=NCCSC(F)(F)F)[nH]cc1c1n(CC)nc(c1C)C(=O)NC[C@@H]1CC[C@H](CC1)S(=O)(=O)C	0.672	0.569	0.7	0.423	0.526	0.69	0.342	0.615	0.437	0.766	0.283
Compound_222	CCC(=O)NCC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1ccc(cc1)F)NC(=O)OCC(C)(C)C	0.653	0.629	0.819	0.586	0.364	0.679	0.139	0.709	0.364	0.928	0.5
Compound_223	FC(COc1cc2c(cc1NC(=O)c1cnn3c1nccc3)cn(c2O)C[C@H](C(O)(C)C)F)F	0.686	0.686	0.179	0.483	0.693	0.65	0.986	0.604	0.377	0.107	0.652
Compound_224	C[C@H]1CCCN1C(=O)c1nc(sc1c1c[nH]c(=NC2CCCC2)cc1C(F)F)C(=O)NCC1(O)COC1	0.633	0.468	0.093	0.376	0.423	0.542	0.033	0.688	0.301	0.097	0.274
Compound_225	CC(NS(=O)(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1ccc(cc1)F)NC(=O)OC(C(F)(F)F)(C)C)C	0.67	0.569	0.877	0.615	0.716	0.666	0.462	0.875	0.357	0.701	0.52
Compound_226	O=C1N(c2ccc(cc2)C(=O)O)c2c(/C/1=C/c1c(Cl)cccc1Cl)c(Cl)ccc2	0.487	0.751	0.294	0.348	0.975	0.949	0.996	0.649	0.41	0.95	0.783
Compound_227	CCS(=O)(=O)c1ccc(cc1)CC(=O)Nc1ccc(cc1)OC1(CCOCC1)c1ccc(cc1Cl)Cl	0.441	0.655	0.982	0.684	0.928	0.772	0.665	0.864	0.376	0.913	0.308
Compound_228	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNS(=O)(=O)C1CC1)S(=O)(=O)c1cn(nc1C)C(F)F	0.71	0.614	0.215	0.63	0.649	0.636	0.471	0.969	0.393	0.886	0.589
Compound_229	OC(=O)CC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)C(F)(F)F)NC(=O)OC(C(F)(F)F)(C)C	0.668	0.639	0.437	0.656	0.568	0.597	0.901	0.917	0.313	0.103	0.523
Compound_230	CCn1nc(c(c1)S(=O)(=O)N1C[C@H](CNC(=O)C)Oc2c1cc(cc2)NC(=O)OC(C)(C)C)C	0.664	0.629	0.145	0.58	0.351	0.599	0.078	0.924	0.387	0.743	0.416
Compound_231	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N([C@@H]([C@@H](O2)CNS(=O)(=O)C)C)S(=O)(=O)c1cn(nc1C)C(F)F	0.704	0.614	0.091	0.671	0.605	0.624	0.638	0.963	0.404	0.735	0.639
Compound_232	OC[C@H](Cn1nc(cc1C)c1cncc(n1)[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F)O	0.603	0.694	0.4	0.603	0.664	0.624	0.93	0.223	0.415	0.039	0.465
Compound_233	Fc1ccc(cc1)S(=O)(=O)[C@@]1(CC[C@@H](CC1)NC(=O)c1cccnc1)c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)O	0.337	0.463	0.255	0.494	0.789	0.505	0.697	0.114	0.331	0.131	0.252
Compound_234	CCS(=O)(=O)c1ccc(cc1)CC(=O)N=c1[nH]c(c(s1)C(=O)c1ccccc1Cl)c1cccc(c1)Cl	0.553	0.571	0.869	0.638	0.638	0.8	0.968	0.431	0.397	0.651	0.263
Compound_235	Fc1ccc(cc1)S(=O)(=O)[C@@]12CC[C@H]([C@@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)NC(c1ccc([nH]1)O)O	0.689	0.422	0.138	0.37	0.716	0.651	0.857	0.47	0.391	0.671	0.384
Compound_236	N#Cc1ccc(cc1Cl)NC(=O)CC(CC(=O)Nc1ccc2c(c1)c(=O)n(c(=O)n2CC1CC1)CC1CC1)C	0.452	0.45	0.809	0.555	0.877	0.704	0.951	0.766	0.676	0.353	0.625
Compound_237	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNC(=O)C1(C)CC1)S(=O)(=O)c1ccc(cc1)F	0.654	0.599	0.948	0.6	0.693	0.613	0.115	0.858	0.378	0.931	0.481
Compound_238	O=C(NC(c1ccc(cc1C)C)c1ccccc1)Cc1ccc2c(c1)cc(o2)C(c1c(C)noc1C)O	0.257	0.658	0.992	0.45	0.553	0.822	0.905	0.76	0.388	0.519	0.637
Compound_239	FC(Oc1cc(F)cc(c1)c1ccc2c(c1)N(C[C@@H](O2)CC1(CCOCC1)C(=O)O)S(=O)(=O)c1cccc(c1)C(F)(F)F)F	0.663	0.65	0.8	0.5	0.77	0.635	0.943	0.701	0.353	0.498	0.46
Compound_240	COc1nc2ccc(cc2c(c1CC(C)C)Cl)[C@](c1cnc(n1C)C)(c1cnnn1C)O	0.63	0.7	0.115	0.543	0.646	0.65	0.982	0.809	0.55	0.951	0.481
Compound_241	CCn1nc(c(c1c1ccc(cc1OC(F)F)[C@@H](C1(CC1)C(F)(F)F)O)Cl)C(=O)NC[C@]1(O)CC[C@H](CC1)S(=O)(=O)C	0.715	0.729	0.039	0.424	0.751	0.686	0.559	0.814	0.405	0.884	0.446
Compound_242	OC1CC(C1)C(=O)N=c1cc(n([nH]1)C(C)C)c1ccc(c(c1)N1CC2C(C1)C2)N(C(=O)c1c(F)cccc1Cl)C	0.707	0.525	0.053	0.466	0.75	0.665	0.403	0.477	0.423	0.24	0.175
Compound_243	CCn1nc(c(c1c1cnc(cc1OC(F)F)CC(C(F)(F)F)(C)C)Cl)C(=O)NC[C@@H]1CC[C@H](CC1)C	0.644	0.698	0.382	0.501	0.647	0.708	0.649	0.956	0.452	0.834	0.25
Compound_244	O=C(N1CCC2(C1)CCN2C)C1CCc2c(C1)n(nc2C1=CCC(CC1)C(=O)O)C(=O)c1c(Cl)cccc1C1CC1	0.798	0.736	0.49	0.293	0.689	0.679	0.941	0.614	0.369	0.663	0.399
Compound_245	Fc1ccc(cc1)S(=O)(=O)[C@@]12CC[C@H]([C@@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C1(F)CCS(=O)(=O)CC1	0.597	0.561	0.212	0.434	0.578	0.578	0.404	0.553	0.397	0.582	0.234
Compound_246	N#Cc1cc(ccc1F)C(=O)Nc1cnc2c(c1C)c(cn2C)[C@@H]1CCN(C(C1)(C)C)C(=O)C1CCCC1	0.614	0.731	0.861	0.55	0.368	0.763	0.954	0.868	0.493	0.825	0.312
Compound_247	FC(CN(C(=O)c1ccc(=O)[nH]c1)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F)F	0.495	0.749	0.071	0.591	0.605	0.57	0.109	0.605	0.504	0.02	0.22
Compound_248	OC[C@H](COC(c1cc(F)c(cc1F)CN1[C@@H](C)CC[C@@H](S1(=O)=O)c1ccccc1)(C)C)O	0.485	0.619	0.08	0.589	0.161	0.719	0.284	0.074	0.39	0.805	0.483
Compound_249	CCn1nc(c(c1c1ccc(cc1OC(F)F)C[C@@H](C(F)(F)F)C)C)C(=O)NC[C@]1(O)CC[C@H](C[C@H]1O)S(=O)(=O)C	0.719	0.709	0.152	0.574	0.673	0.656	0.623	0.956	0.399	0.905	0.409
Compound_250	CCC(OC(=O)Nc1ccc2c(c1)N(C[C@@H](O2)CNC(=O)C)S(=O)(=O)c1cn(nc1C)C(F)F)C	0.693	0.589	0.415	0.568	0.465	0.587	0.295	0.921	0.391	0.831	0.5
Compound_251	CC(Cc1noc(c1)c1onc(c1C1CC1)C(CC(=O)Nc1ccc(cc1Cl)C)CCC(=O)O)C	0.549	0.667	0.462	0.341	0.778	0.656	0.994	0.335	0.387	0.4	0.332
Compound_252	O=C(c1nc(c(s1)c1ccc(c2c1cccc2)S(=O)(=O)NC(C)(C)C)CC1CCCCC1)NC1CS(=O)(=O)C1	0.466	0.542	0.125	0.463	0.538	0.668	0.945	0.922	0.371	0.961	0.35
Compound_253	O[C@@H]1CCC[C@H]1NC(=O)c1nc(c(s1)c1c[nH]c(=N[C@H](C(F)(F)F)C)cc1C(F)F)C(=O)N1CC(C[C@@H]1C)(F)F	0.654	0.48	0.185	0.512	0.444	0.588	0.09	0.822	0.139	0.001	0.123
Compound_254	OC[C@@H](c1ccc(cn1)S(=O)(=O)CC)NC(=O)c1ccc2c(c1)cc(n2CC)C(=O)c1ccc(cn1)C(F)(F)F	0.555	0.516	0.826	0.542	0.687	0.614	0.998	0.509	0.238	0.043	0.393
Compound_255	N#Cc1cccc(c1)c1[nH]c(=NC(=O)Cc2ccc(cc2)S(=O)(=O)CC)sc1Oc1ccccc1C(F)(F)F	0.641	0.516	0.345	0.517	0.654	0.749	0.982	0.333	0.383	0.165	0.447
Compound_256	CC[C@@H](C(F)(F)F)N=c1[nH]cc(c(c1)C(F)F)c1sc(nc1C(=O)N1C2CCC1CC2)C(=O)N[C@H]1CC[C@@H](C1)O	0.636	0.391	0.16	0.455	0.584	0.653	0.101	0.427	0.181	0.004	0.224
Compound_257	OCCC1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)C(F)(F)F)NC(=O)OC(C)(C)C	0.604	0.629	0.386	0.593	0.43	0.624	0.781	0.687	0.287	0.693	0.53
Compound_258	O=C(N1CC2(C1)CCO2)C1CCc2c(C1)n(nc2C1=CCC(CC1)C(=O)O)C(=O)c1c(Cl)cccc1C1CC1	0.795	0.692	0.118	0.367	0.737	0.689	0.811	0.642	0.357	0.643	0.426
Compound_259	CCS(=O)(=O)c1ccc(cc1)CC(=O)Nc1ccc(cc1)CCN1CCCc2c1cc(cc2)CC(C)(C)C	0.405	0.584	0.179	0.486	0.782	0.608	0.945	0.333	0.395	0.713	0.134
Compound_260	Fc1cccc(c1c1nnc2c(c1)[C@@H]1CC[C@]2(C1(C)C)c1cncc(n1)c1occ(n1)[C@@H](N)C)F	0.57	0.733	0.471	0.606	0.68	0.653	0.99	0.499	0.608	0.425	0.27
Compound_261	OCCOc1nn(cc1S(=O)(=O)N1C[C@H](CNC(=O)C(O)(C)C)Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)C(C)C	0.686	0.719	0.351	0.52	0.476	0.612	0.432	0.656	0.343	0.617	0.464
Compound_262	OC(=O)c1ccc(c(c1)F)c1nn(c2c1CCOC2)C(=O)c1c(Cl)cccc1C1CC1	0.598	0.755	0.454	0.529	0.84	0.728	0.953	0.338	0.425	0.13	0.435
Compound_263	CCn1nc(c(c1c1c[nH]c(=NC(CC(F)(F)F)(C)C)cc1OC(F)F)Cl)C(=O)NC[C@H]1CC[C@@H](C[C@@H]1O)S(=O)(=O)C	0.664	0.599	0.029	0.466	0.626	0.7	0.811	0.86	0.404	0.916	0.367
Compound_264	C[C@H](Cn1ncc(c1)c1cncc(n1)[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F)O	0.531	0.767	0.281	0.57	0.658	0.622	0.891	0.627	0.48	0.059	0.36
Compound_265	OCC(c1cc(F)c(cc1F)CN1[C@@H](C)CC[C@@H](S1(=O)=O)c1ccccc1)c1ccccc1	0.416	0.517	0.077	0.558	0.316	0.722	0.237	0.348	0.379	0.018	0.403
Compound_266	O=C(C1CC1)N=c1cc(n([nH]1)C(C)C)c1ccc(c(c1)N1CC2C(C1)C2)N(C(=O)c1c(F)cccc1Cl)C	0.715	0.674	0.161	0.518	0.699	0.712	0.826	0.395	0.477	0.437	0.108
Compound_267	Fc1ccc(cc1)S(=O)(=O)N1CC(CC(=O)N=c2scn[nH]2)Sc2c1ccc(c2)C(C(F)(F)F)(C(F)(F)F)O	0.621	0.591	0.808	0.491	0.764	0.66	0.789	0.219	0.284	0.031	0.337
Compound_268	CC(N(C(=O)c1nc(sc1c1ccc(c(c1Cl)Cl)S(=O)(=O)N[C@H](C(F)(F)F)C)C(=O)NCC(O)(C)C)C(C)C)C	0.505	0.496	0.207	0.469	0.693	0.656	0.705	0.824	0.307	0.656	0.418
Compound_269	F[C@@H](C(O)(C)C)Cn1cc2c(c1O)cc(c(c2)NC(=O)c1cnn2c1nccc2)OC1CC1	0.685	0.646	0.079	0.553	0.686	0.651	0.936	0.631	0.396	0.059	0.568
Compound_270	Fc1cccc(c1c1nnc2c(c1)[C@@H]1CC[C@]2(C1(C)C)c1cncc(n1)c1cc[nH]c(=NS(=O)(=O)C)n1)F	0.588	0.599	0.233	0.52	0.533	0.61	0.957	0.518	0.451	0.581	0.664
Compound_271	Fc1ccc(cc1)S(=O)(=O)C1(CCCC1)c1ccc(cc1)C(c1ccccc1)(F)F	0.798	0.608	0.468	0.595	0.884	0.776	0.951	0.835	0.43	0.969	0.388
Compound_272	Fc1ccc(cc1)S(=O)(=O)C1(CCCC1)c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)OCc1ccc2c(c1)cccc2	0.721	0.641	0.695	0.638	0.934	0.812	0.869	0.903	0.405	0.938	0.492
Compound_273	CC[C@@H](C(F)(F)F)N=c1[nH]cc(c(c1)C(F)F)c1sc(nc1C(=O)N1CC(C[C@@H]1C)(F)F)C(=O)NC1CCS(=O)(=O)CC1	0.635	0.518	0.572	0.483	0.375	0.661	0.012	0.859	0.357	0.284	0.233
Compound_274	CCOc1sc(nc1S(=O)(=O)N1C[C@H](CC(C(=O)O)C)Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)CC	0.682	0.638	0.183	0.654	0.55	0.649	0.794	0.976	0.312	0.808	0.485
Compound_275	CCS(=O)(=O)c1ccc(cc1)CC(=O)N=c1sc2c([nH]1)[C@@H](N(C2)Cc1ccc(cc1)F)C(C)C	0.452	0.639	0.124	0.279	0.385	0.656	0.14	0.232	0.367	0.803	0.378
Compound_276	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(CC(O2)c1n[nH]c(=O)o1)S(=O)(=O)c1cn(nc1C)C(F)F	0.666	0.586	0.178	0.564	0.586	0.631	0.673	0.843	0.387	0.753	0.537
Compound_277	Fc1ccc(cc1)S(=O)(=O)Nc1ccc2c(c1)c(cn2C)C1CCN(CC1)C(=O)C1CC1	0.542	0.648	0.664	0.487	0.239	0.693	0.986	0.734	0.306	0.097	0.37
Compound_278	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNS(=O)(=O)c1c(C)noc1C)S(=O)(=O)c1ccc(c(c1)Cl)F	0.666	0.544	0.933	0.44	0.747	0.659	0.581	0.94	0.379	0.828	0.64
Compound_279	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNC(=O)C1CC(C1)(F)F)S(=O)(=O)c1ccc(c(c1)Cl)F	0.681	0.529	0.98	0.599	0.746	0.652	0.134	0.891	0.389	0.356	0.598
Compound_280	O=C(C[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)C(F)(F)F)NC(=O)OC(C)(C)C)NCc1cnn(c1)C	0.627	0.629	0.152	0.602	0.533	0.617	0.651	0.68	0.354	0.93	0.523
Compound_281	Fc1ccc(cc1)S(=O)(=O)[C@]12CC[C@H]([C@@H]2CCc2c1ccc(c2)C(C(F)(F)F)(C(F)(F)F)F)n1c(=O)[nH]c(c1O)CC(O)(C)C	0.629	0.619	0.383	0.537	0.577	0.613	0.586	0.549	0.377	0.286	0.34
Compound_282	C[C@@H]([C@H](NC(=O)c1nc(c(s1)c1c[nH]c(=NC(C)(C)C)cc1C(F)(F)F)C(=O)N1CCC[C@@H]1C)C)O	0.61	0.458	0.04	0.427	0.261	0.609	0.079	0.865	0.237	0.069	0.221
Compound_283	C[C@H]1CCCCN1C(=O)c1nc(sc1c1c[nH]c(=N[C@H]2CCCCC2(F)F)cc1C(F)(F)F)C(=O)NCC(O)(C)C	0.637	0.559	0.055	0.413	0.481	0.672	0.083	0.781	0.308	0.26	0.179
Compound_284	O[C@@H]1C[C@H](O)CN(C1)C(=O)c1nc(c(s1)c1ccc(cc1OC(F)(F)F)C(C(F)(F)F)(C(F)(F)F)O)C(=O)N1CC(C[C@@H]1C)(F)F	0.697	0.589	0.668	0.809	0.544	0.702	0.517	0.628	0.269	0.39	0.677
Compound_285	CCS(=O)(=O)c1ccc(cc1)CC(=O)Nc1ccc(cc1)CCN1CCOc2c1cc(cc2)OC(C)C	0.547	0.67	0.534	0.524	0.786	0.558	0.925	0.566	0.393	0.983	0.198
Compound_286	CCn1nc(c(c1c1ccc(cc1OC(F)F)CC(C(F)(F)F)(C)C)Cl)C(=O)NC[C@@H]1CC[C@H](C[C@H]1O)S(=O)(=O)C	0.689	0.729	0.081	0.535	0.718	0.712	0.696	0.976	0.404	0.982	0.39
Compound_287	CC(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1ccc(cc1)F)NC(=O)OC(C(C(F)(F)F)(F)F)C1CCCCC1	0.713	0.498	0.957	0.619	0.724	0.629	0.153	0.798	0.377	0.363	0.5
Compound_288	COc1cc(=NCCCC(F)(F)F)[nH]cc1c1n(CC)nc(c1Cl)C(=O)NC[C@@H]1CC[C@H](CC1)S(=O)(=O)C	0.688	0.579	0.443	0.422	0.586	0.754	0.656	0.708	0.45	0.851	0.294
Compound_289	C[C@H]1CCCN1C(=O)c1nc(sc1c1c[nH]c(=NC(C)(C)C)cc1C(F)(F)F)C(=O)N[C@H]1COCC1	0.628	0.599	0.088	0.412	0.405	0.653	0.044	0.833	0.387	0.433	0.291
Compound_290	N#Cc1ccc(nc1)CN1Cc2c([C@]1(C)C(C)C)[nH]c(=NC(=O)Cc1ccc(cc1)S(=O)(=O)CC)s2	0.482	0.639	0.099	0.238	0.4	0.658	0.057	0.597	0.373	0.301	0.423
Compound_291	CCS(=O)(=O)c1ccc(cc1)CC(=O)N=c1sc2c([nH]1)[C@@H](N(C2)[C@@H](c1cc(Br)ccc1F)C)C(C)C	0.516	0.649	0.203	0.344	0.667	0.645	0.155	0.289	0.393	0.911	0.429
Compound_292	FC(Oc1cc(ccc1c1n(nc(c1C)C(=O)NC[C@]1(O)CC[C@H](CC1)S(=O)(=O)C)CC(O)(C)C)CC(C(F)(F)F)(C)C)F	0.721	0.719	0.165	0.513	0.714	0.68	0.615	0.952	0.405	0.965	0.377
Compound_293	Fc1ccc(cc1)S(=O)(=O)[C@@]12CCN([C@@H]1CCc1c2ccc(c1)OCc1c(F)cccc1C(F)(F)F)C(=O)C1CCN(CC1)C(=O)N	0.664	0.555	0.335	0.364	0.83	0.732	0.821	0.465	0.387	0.081	0.319
Compound_294	Fc1ccc(cc1)S(=O)(=O)C1(CCCC1)c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)OCc1cc(Cl)ccc1F	0.698	0.713	0.551	0.671	0.955	0.86	0.601	0.717	0.395	0.962	0.577
Compound_295	C[C@H]1OC[C@@H](S(=O)(=O)N(C1)Cc1ccc(cc1F)N1CCN(CC1)C(=O)C)c1ccccc1	0.496	0.767	0.164	0.502	0.587	0.728	0.28	0.973	0.407	0.531	0.414
Compound_296	C[C@H]1CCCN1C(=O)c1nc(sc1c1c[nH]c(=N[C@H](C(F)(F)F)C2CC2)cc1C(F)F)C(=O)N[C@H](C(O)(C)C)C	0.644	0.498	0.297	0.473	0.5	0.64	0.039	0.822	0.328	0.11	0.254
Compound_297	CC(=O)N1CC2CC(C1)N2c1ccc2c(c1)CCN(C2)S(=O)(=O)N(Cc1c(F)cccc1Cl)C	0.431	0.628	0.72	0.531	0.647	0.654	0.313	0.954	0.407	0.556	0.467
Compound_298	COc1cc(ccc1F)S(=O)(=O)N1C[C@H](CNC(=O)C)Oc2c1cc(cc2)NC(=O)OCC1(CC1)C(F)(F)F	0.67	0.579	0.89	0.603	0.691	0.662	0.16	0.822	0.351	0.352	0.52
Compound_299	N#CCCC(=O)N1Cc2c(C1C(=O)Nc1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)O)ccc(c2)S(=O)(=O)CC	0.432	0.558	0.239	0.571	0.754	0.612	0.902	0.702	0.392	0.663	0.533
Compound_300	COc1nc2ccc(cc2c(c1CN1CCC(CC1)(O)C(F)(F)F)Cl)[C@](c1cncn1C)(c1ccnc(c1)C(F)(F)F)O	0.612	0.656	0.268	0.359	0.813	0.664	0.992	0.295	0.386	0.248	0.66
Compound_301	Fc1cccc(c1COc1ccc2c(c1)N(CC2)S(=O)(=O)c1cccc(c1)C(F)(F)F)Cl	0.542	0.428	0.961	0.673	0.922	0.751	0.754	0.798	0.192	0.396	0.637
Compound_302	CCS(=O)(=O)c1ccc(cc1)CC(=O)Nc1ccc(c(c1)Cl)c1ccccc1	0.395	0.429	0.963	0.74	0.911	0.78	0.962	0.376	0.38	0.709	0.18
Compound_303	CCn1nc(c(c1)S(=O)(=O)N1[C@@H](C)[C@@H](Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)CC(C(=O)O)(C)C)Cl	0.678	0.596	0.264	0.672	0.506	0.592	0.815	0.884	0.351	0.94	0.561
Compound_304	CCn1nc(c(c1)S(=O)(=O)N1C[C@H](CNC(=O)C(O)(C)C)Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)OCC(F)F	0.711	0.678	0.488	0.519	0.566	0.615	0.315	0.521	0.343	0.636	0.489
Compound_305	CCS(=O)(=O)c1ccc(cc1)CC(=O)N=c1sc2c([nH]1)[C@@H](N(C2)CC1CCC(CC1)C(F)F)C(C)C	0.475	0.569	0.08	0.203	0.44	0.662	0.906	0.778	0.37	0.844	0.332
Compound_306	CCn1nc(c(c1c1ccc(cc1OC(F)F)CC(C(F)(F)F)(C)C)Cl)C(=O)NC[C@@H]1CC[C@H](CC1)S(=O)(=O)NC(=O)N	0.715	0.729	0.296	0.47	0.724	0.759	0.732	0.934	0.4	0.534	0.428
Compound_307	Clc1ccc(c(c1)S(=O)(=O)N(C1CCC1)Cc1ccc(cc1F)N1CCN(CC1)C(=O)C)Cl	0.378	0.629	0.469	0.64	0.711	0.655	0.13	0.89	0.407	0.268	0.368
Compound_308	N#Cc1cccc(c1)C(=O)Nc1cnc2c(c1C)c(cn2C)[C@@H]1CCN(C[C@@H]1C)C(=O)C1CCCC1	0.589	0.698	0.253	0.589	0.304	0.774	0.948	0.67	0.482	0.427	0.34
Compound_309	CC(CNC(=O)C[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)C(F)(F)F)NC(=O)OC(C)(C)C)C	0.614	0.589	0.221	0.521	0.485	0.65	0.393	0.823	0.341	0.852	0.5
Compound_310	CCS(=O)(=O)c1ccc(cc1)CC(=O)N=c1[nH]c2c(s1)CN([C@H]2C(C)C)Cc1ccc(cn1)OC(F)F	0.523	0.518	0.17	0.296	0.399	0.654	0.595	0.816	0.391	0.688	0.37
Compound_311	OCC1CCc2c(C1)n(nc2c1ccc(cc1F)C(=O)O)C(=O)c1c(Cl)cccc1C1CC1	0.623	0.669	0.288	0.516	0.877	0.769	0.916	0.31	0.403	0.13	0.537
Compound_312	CCS(=O)(=O)c1ccc(cc1)CC(=O)Nc1ccc2c(c1)ccn2CCc1ccc(cc1)OC(C)C	0.475	0.612	0.99	0.606	0.665	0.822	0.993	0.334	0.362	0.357	0.194
Compound_313	Fc1ccc(cc1)S(=O)(=O)N1C(C)COc2c1cc(cn2)NC(=O)c1c(Cl)cccc1C(F)(F)F	0.653	0.487	0.607	0.688	0.595	0.663	0.943	0.971	0.387	0.721	0.582
Compound_314	Fc1ccc(cc1)S(=O)(=O)[C@@]12CC[C@H]([C@@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)N1CC(C1)(C)O	0.538	0.528	0.103	0.459	0.619	0.598	0.727	0.519	0.391	0.413	0.45
Compound_315	OC(=O)C1CCN(C(=O)C1)c1nn(c2c1c(F)ccc2)C(=O)c1c(Cl)cccc1C(F)(F)F	0.573	0.643	0.704	0.488	0.806	0.728	0.978	0.969	0.39	0.183	0.275
Compound_316	C[C@H]1CC[C@@H](S(=O)(=O)C1Cc1ccc(cc1F)N1CCC2(CC1)N(C)C(=O)N(C2=O)C)c1ccccc1	0.729	0.738	0.23	0.483	0.744	0.717	0.14	0.888	0.422	0.954	0.239
Compound_317	O=C(C1CC[C@@]2([C@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccc(cc1)F)NCC(O)(C)C	0.511	0.626	0.068	0.27	0.628	0.657	0.743	0.521	0.4	0.146	0.252
Compound_318	Fc1cccc(c1c1nnc2c(c1)[C@@H]1CC[C@]2(C1(C)C)c1cccc(n1)n1cnc(n1)CC1CS(=O)(=O)C1)F	0.644	0.607	0.134	0.584	0.669	0.646	0.957	0.929	0.536	0.023	0.518
Compound_319	CCS(=O)(=O)c1ccc(cc1)CNC(c1sc2c(n1)c(n(c2)Cc1ccc(cc1)Cl)C(C)C)O	0.605	0.536	0.935	0.334	0.559	0.688	0.971	0.336	0.341	0.541	0.296
Compound_320	CCn1nc(c(c1)S(=O)(=O)N1C[C@H](Oc2c1cc(cc2)N(C(C(F)(F)F)(C)C)C(=O)O)CC(C(=O)N)(C)C)Cl	0.695	0.619	0.277	0.388	0.491	0.596	0.666	0.128	0.381	0.887	0.524
Compound_321	N#Cc1cccc(c1)S(=O)(=O)N1C[C@@H](Oc2c1cc(cc2)NC(=O)O[C@H]1CC2CC1CC2)Cn1c(O)coc1=O	0.728	0.539	0.456	0.562	0.629	0.654	0.219	0.892	0.317	0.191	0.5
Compound_322	Fc1cc(ccc1c1nn(c2c1nccc2)C(=O)c1c(Cl)c(F)ccc1C1(CC1)C(F)(F)F)C(=O)O	0.487	0.644	0.441	0.545	0.825	0.67	0.994	0.946	0.431	0.137	0.637
Compound_323	OC(=O)CCNC(=O)C1Oc2ccc(cc2N(C1)S(=O)(=O)c1ccc(c(c1)Cl)F)NC(=O)OC(C)(C)C	0.67	0.619	0.759	0.475	0.657	0.648	0.11	0.59	0.386	0.763	0.575
Compound_324	FC1CC(C1)C(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1ccc(cc1)F)NC(=O)OC(C(F)(F)F)(C)C	0.659	0.529	0.758	0.596	0.747	0.648	0.072	0.886	0.371	0.106	0.561
Compound_325	COc1nc2ccc(cc2c(c1OC(C1CC1)C)Cl)C(c1cnc(n1C)C)(c1cnc(n1C)C)O	0.655	0.647	0.141	0.565	0.668	0.642	0.961	0.657	0.52	0.791	0.592
Compound_326	CCCN(Cc1ccc(cc1)OC1CCCC1)Cc1ccc(cc1)NC(=O)Cc1ccc(cc1)S(=O)(=O)CC	0.315	0.475	0.316	0.384	0.804	0.9	0.726	0.405	0.382	0.059	0.116
Compound_327	Fc1cccc(c1c1nnc2c(c1)[C@@H]1CC[C@]2(C1(C)C)c1cncc(n1)c1cnc(nc1)CS(=O)(=O)C)F	0.497	0.588	0.559	0.576	0.668	0.647	0.979	0.929	0.437	0.211	0.382
Compound_328	OCC1CCC(C1)(c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)OCc1c(F)cccc1F)S(=O)(=O)c1ccc(cc1)F	0.636	0.603	0.15	0.647	0.925	0.679	0.615	0.183	0.374	0.93	0.39
Compound_329	Fc1cccc(c1c1nnc2c(c1)[C@@H]1CC[C@]2(C1(C)C)c1ccnc(n1)n1ccc(n1)C(F)F)F	0.652	0.555	0.551	0.703	0.671	0.638	0.962	0.648	0.438	0.024	0.59
Compound_330	N#Cc1cc(ccc1CC1CCN(CC1)C(=O)C(C)(C)C)c1ccc(cc1C(F)(F)F)NC(=O)Cc1ccc(cc1)S(=O)(=O)CC	0.505	0.6	0.592	0.662	0.858	0.579	0.914	0.861	0.407	0.79	0.431
Compound_331	CC[C@@H](C(F)(F)F)N=c1[nH]cc(c(c1)C(F)F)c1sc(nc1C(=O)N1CCC[C@@H]1C)C(=O)N[C@@H]1C[C@@H]1O	0.627	0.478	0.21	0.461	0.467	0.62	0.079	0.379	0.29	0.001	0.303
Compound_332	OC(=O)C1CC(C1)NC(=O)c1nc(c(s1)c1ccc(c(c1Cl)Cl)S(=O)(=O)NC(C)(C)C)CC1CCCCC1	0.505	0.654	0.038	0.386	0.697	0.653	0.9	0.778	0.39	0.988	0.334
Compound_333	CC(CC1CC(C1)c1nnc(n1C1CC1)C1C[C@@H](CC1C(=O)Nc1ccc(cc1C)C)O)C	0.468	0.643	0.691	0.508	0.5	0.664	0.103	0.392	0.41	0.415	0.372
Compound_334	CCC(N=c1[nH]cc(c(c1)C(F)F)c1sc(nc1C(=O)N1CCC[C@@H]1C)C(=O)NCC(O)(C)C)(C)C	0.616	0.529	0.087	0.39	0.314	0.666	0.143	0.78	0.409	0.085	0.264
Compound_335	O[C@@H]1CC[C@H]1NC(=O)c1nc(c(s1)c1c[nH]c(=NC(C)(C)C)cc1C(F)F)C(=O)N1CCC[C@@H]1C	0.63	0.559	0.063	0.459	0.413	0.645	0.079	0.859	0.287	0.028	0.245
Compound_336	CC(=O)N=c1cc(n([nH]1)CC(C)(C)C)c1ccc(c(c1)N1CC2C(C1)C2)N(C(=O)c1c(F)cccc1Cl)C	0.679	0.666	0.089	0.541	0.645	0.825	0.94	0.355	0.543	0.458	0.17
Compound_337	O=C(C1CC(C1)(c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccc(cc1)F)NCC1CCOCC1	0.397	0.491	0.166	0.364	0.692	0.648	0.429	0.594	0.391	0.272	0.341
Compound_338	CCn1nc(c(c1c1ccc(cc1OC(F)F)CC(C(F)(F)F)(C)C)Cl)C(=O)NC[C@@]1(O)CC[C@H](C[C@@H]1O)S(=O)(=O)C	0.698	0.749	0.058	0.558	0.721	0.682	0.546	0.956	0.404	0.966	0.405
Compound_339	CCN(S(=O)(=O)c1ccc(c(c1)F)F)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.408	0.699	0.173	0.647	0.594	0.595	0.764	0.77	0.398	0.978	0.414
Compound_340	N#Cc1cc(ccc1OC)C(=O)Nc1cnc2c(c1C)c(cn2C)C1CCN(CC1)C(=O)C(C(C)(C)C)C	0.619	0.735	0.668	0.594	0.297	0.8	0.711	0.724	0.511	0.67	0.61
Compound_341	CCN(C(=O)CN1CC(C1)O)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.353	0.659	0.338	0.432	0.536	0.582	0.09	0.737	0.379	0.608	0.273
Compound_342	COc1nn(c(c1S(=O)(=O)N1C[C@H](CCC(=O)O)Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)C)C	0.728	0.609	0.226	0.646	0.59	0.625	0.765	0.866	0.359	0.947	0.475
Compound_343	CN(CCNC(=O)C1CCc2c(C1)n(nc2c1ccc(cc1F)C(=O)O)C(=O)c1c(Cl)cccc1C1(CC1)C(F)(F)F)C	0.648	0.765	0.006	0.463	0.879	0.746	0.956	0.826	0.376	0.33	0.379
Compound_344	CC(=O)N=c1cc(n([nH]1)C(C)C)c1ccc(c(c1)N1CCCC1)N(C([2H])([2H])[2H])C(=O)c1c(F)cccc1Cl	0.697	0.667	0.077	0.538	0.539	0.818	0.757	0.348	0.608	0.702	0.077
Compound_345	OCC(c1ccc(cc1)S(=O)(=O)CC)NC(=O)c1ccc(cc1)CCN1CCCc2c1cc(cc2)CC(C)C	0.371	0.596	0.013	0.301	0.668	0.582	0.915	0.599	0.388	0.576	0.192
Compound_346	CCn1nc(c(c1c1ccc(cc1OC(F)F)C[C@H](C(F)(F)F)C)Cl)C(=O)NC[C@]1(O)CC[C@H](CC1)S(=O)(=O)C	0.709	0.719	0.154	0.514	0.731	0.691	0.691	0.956	0.401	0.99	0.419
Compound_347	N#Cc1cc(C)c2c(c1)n(C)c(c2)Cc1c(Cl)ccc(c1Cl)C(=O)N1CCC(C1)O	0.493	0.524	0.782	0.582	0.815	0.629	0.922	0.899	0.439	0.041	0.558
Compound_348	Fc1ccc(cc1)S(=O)(=O)[C@@]12CC[C@H]([C@@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)NC(C(=O)C(F)(F)F)O	0.628	0.513	0.558	0.419	0.572	0.593	0.853	0.651	0.402	0.417	0.392
Compound_349	COc1nn2c(c1S(=O)(=O)N1C[C@@H](Oc3c1cc(cc3)NC(=O)OC(C(F)(F)F)(C)C)CC(C(=O)O)(C)C)CCC2	0.732	0.668	0.39	0.624	0.646	0.636	0.738	0.86	0.36	0.903	0.435
Compound_350	Fc1ccc(cc1)S(=O)(=O)[C@@]12CC[C@H]([C@@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)c1ccc(=O)[nH]c1	0.586	0.549	0.051	0.401	0.614	0.585	0.801	0.615	0.424	0.206	0.364
Compound_351	FC1CCN(CC1)C(=O)c1nc(sc1c1c[nH]c(=N[C@@H](C2CC2)C)cc1C(F)(F)F)C(=O)NCC(O)(C)C	0.653	0.549	0.101	0.398	0.5	0.619	0.014	0.804	0.372	0.188	0.186
Compound_352	COc1cc(=NC(CC(F)(F)F)(C)C)[nH]cc1c1n(CC)nc(c1Cl)C(=O)NC[C@@H]1CC[C@H](CC1)S(=O)(=O)C	0.668	0.619	0.046	0.453	0.564	0.753	0.656	0.839	0.447	0.902	0.318
Compound_353	OC(=O)C[C@@H]1CCN(C[C@@H]1C)C(=O)c1ccc(c(c1Cl)C(=O)c1cc2c(n1C)nc(cc2C)C(F)(F)F)Cl	0.576	0.693	0.497	0.476	0.651	0.716	0.976	0.979	0.409	0.87	0.355
Compound_354	CC(=O)N[C@H]([C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cn(nc1C)C(F)F)NC(=O)OC(C(F)(F)F)(C)C)C	0.709	0.616	0.552	0.602	0.566	0.604	0.403	0.942	0.362	0.872	0.607
Compound_355	CCS(=O)(=O)c1ccc(cc1)CC(=O)Nc1ccc(cc1)CCN1CCCc2c1cc(cc2)C(C)C	0.391	0.598	0.136	0.455	0.708	0.56	0.969	0.368	0.39	0.569	0.116
Compound_356	O=C(OC(C)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)Cn1cncn1)S(=O)(=O)c1cccc(c1)C(F)(F)F	0.621	0.591	0.528	0.683	0.397	0.667	0.971	0.852	0.343	0.833	0.549
Compound_357	C[C@H]1CCCN1C(=O)c1nc(sc1c1c[nH]c(=NC(C)(C)C)cc1C(F)(F)F)C(=O)N	0.563	0.539	0.018	0.412	0.261	0.656	0.168	0.745	0.344	0.085	0.168
Compound_358	COCCC1CCN(CC1)C(=O)c1ccc(c(c1Cl)Cc1cc2c(n1C)cc(cc2C)C#N)Cl	0.604	0.702	0.868	0.559	0.799	0.7	0.995	0.936	0.45	0.649	0.75
Compound_359	COCCc1cn(nc1CCS(=O)(=O)C)c1nccc(n1)[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.666	0.729	0.433	0.612	0.647	0.644	0.988	0.776	0.412	0.45	0.561
Compound_360	CCN(C(=O)c1ccc2c(c1)nc([nH]2)C)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.52	0.771	0.983	0.635	0.632	0.656	0.995	0.7	0.415	0.963	0.141
Compound_361	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNS(=O)(=O)N1CCOCC1)S(=O)(=O)c1ccc(cc1)F	0.673	0.558	0.73	0.639	0.72	0.654	0.333	0.916	0.377	0.117	0.546
Compound_362	OC(=O)c1ccc(c(c1)F)c1nn(c2c1nccc2)C(=O)c1c(C)cccc1N(C)C	0.454	0.715	0.691	0.492	0.577	0.542	0.987	0.514	0.491	0.709	0.198
Compound_363	Fc1cccc(c1c1nnc2c(c1)[C@@H]1CC[C@]2(C1(C)C)c1ccnc(n1)c1cc[nH]c(=NS(=O)(=O)C)c1)F	0.66	0.679	0.839	0.677	0.589	0.619	0.895	0.609	0.419	0.613	0.586
Compound_364	O=C(c1ccc(c(c1Cl)C(=O)c1cc2c(n1C)cc(cc2C)C(F)(F)F)Cl)N1CCN(CC1)C1COC1	0.527	0.565	0.935	0.37	0.666	0.615	0.932	0.82	0.415	0.136	0.397
Compound_365	CC(Cc1nnc(s1)c1onc(c1C1CC1)C(CC(=O)Nc1ccc(cc1Cl)C)CCC(=O)O)C	0.655	0.668	0.414	0.321	0.69	0.657	0.989	0.316	0.397	0.904	0.334
Compound_366	Clc1ccc(c(c1Cc1nc2n(c1C)nc(cc2C)C(F)(F)F)Cl)C(=O)N1CCC(CC1)C1COC1	0.584	0.628	0.023	0.554	0.645	0.735	0.973	0.969	0.447	0.356	0.368
Compound_367	CCN(C1Cc2ncc(cc2N(C1)S(=O)(=O)c1cccc(c1)C)NC(=O)c1c(Cl)cccc1Cl)CC	0.613	0.639	0.447	0.283	0.439	0.782	0.224	0.256	0.41	0.423	0.283
Compound_368	N#Cc1cccc(c1)C(=O)Nc1cnc2c(c1C(F)(F)F)c(cn2C)[C@@H]1CCN(C(C1)(C)C)C(=O)C1CCCC1	0.629	0.741	0.772	0.647	0.413	0.764	0.982	0.941	0.465	0.812	0.421
Compound_369	CCc1ccc(cc1)CN1Cc2c([C@@H]1C(C)C)[nH]c(=NC(=O)Cc1ccc(cc1)S(=O)(=O)CC)s2	0.398	0.579	0.055	0.19	0.24	0.696	0.541	0.128	0.365	0.515	0.289
Compound_370	OCC(Cc1nnc(o1)C[C@@H]1CCc2c(N1S(=O)(=O)c1ccc(cc1)F)ccc(c2)C(C(F)(F)F)(C(F)(F)F)O)O	0.672	0.616	0.685	0.578	0.709	0.627	0.85	0.109	0.377	0.04	0.5
Compound_371	OC[C@@H](c1ccc(cn1)S(=O)(=O)CC)NC(=O)c1ccc2c(c1)nc(n2Cc1cccc2c1OC(O2)(F)F)C1CCC1	0.599	0.473	0.028	0.468	0.671	0.652	0.986	0.532	0.301	0.308	0.4
Compound_372	CC[C@@H](C(F)(F)F)N=c1[nH]cc(c(c1)C(F)F)c1sc(nc1C(=O)N1CCC[C@@H]1C)C(=O)N[C@@H]([C@@H](O)C)C	0.624	0.408	0.21	0.449	0.398	0.596	0.079	0.379	0.171	0.039	0.234
Compound_373	N#Cc1cccc(c1)C(=O)Nc1cnc2c(c1C)c(cn2C)C1CCN(CC1)C(=O)C(C12CC(C1)C2)C	0.589	0.676	0.153	0.585	0.676	0.66	0.948	0.486	0.464	0.675	0.492
Compound_374	CCS(=O)(=O)c1ccc(cc1)CNC(=O)c1ccc2c(c1)nc(n2Cc1cccc(c1O)O)C1CC1	0.431	0.585	0.117	0.453	0.746	0.682	0.761	0.49	0.382	0.116	0.228
Compound_375	O=C(C[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)C(F)(F)F)NC(=O)OC(C)(C)C)NOCc1ccccc1	0.649	0.609	0.914	0.632	0.649	0.668	0.936	0.923	0.37	0.973	0.614
Compound_376	FC(Oc1cc(F)cc(c1)c1ccc2c(c1)N(CC2)S(=O)(=O)c1cccc(c1)C(F)(F)F)F	0.46	0.475	0.959	0.706	0.7	0.795	0.956	0.7	0.35	0.086	0.537
Compound_377	O=C1NC(=O)C2(N1)CCN(CC2)C(=O)C1CC(C1)(c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccc(cc1)F	0.367	0.515	0.292	0.375	0.73	0.642	0.383	0.408	0.4	0.312	0.39
Compound_378	OC[C@@]1(CC[C@@H](CC1)S(=O)(=O)C)CNC(=O)c1nn(c(c1Cl)c1ccc(cc1OC)CC(C(F)(F)F)C)CC	0.718	0.709	0.129	0.579	0.676	0.756	0.746	0.907	0.42	0.977	0.418
Compound_379	Clc1cccc(c1)S(=O)(=O)N(C1CCC1)Cc1ccc(cc1F)N1CCN(CC1)C(=O)C	0.411	0.629	0.494	0.587	0.728	0.657	0.13	0.857	0.405	0.268	0.368
Compound_380	CC1CCN(C1)S(=O)(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1ccc(c(c1)Cl)F)NC(=O)OC(C(F)(F)F)(C)C	0.675	0.658	0.964	0.627	0.75	0.664	0.72	0.943	0.392	0.906	0.561
Compound_381	O=COC(Cc1onc(n1)c1sc(c(n1)CC1CCCCC1)c1cc(cc(c1)C1(C)CC1)C(=O)N[C@H](C(F)(F)F)C)(C)C	0.669	0.699	0.174	0.543	0.61	0.713	0.986	0.811	0.42	0.988	0.517
Compound_382	N#CCCc1ncn(n1)c1nccc(n1)[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.622	0.545	0.216	0.605	0.667	0.645	0.962	0.83	0.445	0.003	0.699
Compound_383	CC(=O)N1CCN(CC1)c1ccc(c(c1)F)CN1CCCCN(S1(=O)=O)c1ccccc1	0.415	0.635	0.185	0.515	0.689	0.826	0.045	0.929	0.404	0.241	0.269
Compound_384	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CC1(CC1)C(=O)O)S(=O)(=O)c1cccc(c1)C(F)(F)F	0.682	0.599	0.507	0.641	0.646	0.615	0.914	0.933	0.365	0.323	0.552
Compound_385	CCn1nc(c(c1c1ccc(cc1OC(F)F)C[C@@H](C(F)(F)F)C)Cl)C(=O)NC[C@@H]1CC[C@H](CC1)S(=O)(=O)C	0.687	0.659	0.425	0.53	0.709	0.725	0.704	0.955	0.417	0.973	0.314
Compound_386	CCn1nc(c(c1)S(=O)(=O)N1C[C@H](CNC(=O)C)Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)OCC(F)F	0.699	0.628	0.247	0.559	0.576	0.601	0.381	0.892	0.373	0.609	0.49
Compound_387	OCCNC(=O)c1ccc2c(c1)n(nc2c1ccc(cc1)C(=O)O)C(=O)c1c(Cl)cccc1C(F)(F)F	0.415	0.739	0.803	0.437	0.872	0.766	0.987	0.318	0.287	0.325	0.723
Compound_388	CCOC(=O)NC1Cc2ncc(cc2N(C1)S(=O)(=O)c1cccc(c1)C(F)(F)F)NC(=O)c1c(Cl)cccc1Cl	0.672	0.478	0.866	0.56	0.565	0.764	0.899	0.906	0.37	0.365	0.549
Compound_389	OCCN(C(=O)c1noc(c1)C)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.526	0.718	0.325	0.653	0.647	0.629	0.88	0.282	0.419	0.167	0.266
Compound_390	OC[C@@H](c1ccc(cc1)S(=O)(=O)CC)NC(=O)c1cnc2c(c1)CN(C2CC)C[C@H]1CC[C@@H](OC1)C(F)(F)F	0.526	0.614	0.023	0.259	0.368	0.499	0.817	0.26	0.388	0.153	0.402
Compound_391	O[C@H]1COC[C@H]1NC(=O)c1nc(c(s1)c1c[nH]c(=NC2(C)CCC2)cc1C(F)(F)F)C(=O)N1CC(C[C@@H]1C)(F)F	0.692	0.534	0.114	0.435	0.592	0.649	0.052	0.67	0.305	0.101	0.276
Compound_392	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@H](O2)CCN1CCCC1=O)S(=O)(=O)c1cccc(c1)C(F)(F)F	0.644	0.588	0.322	0.641	0.555	0.626	0.91	0.941	0.342	0.582	0.5
Compound_393	CCN(C(=O)c1cnccn1)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.475	0.744	0.241	0.634	0.518	0.595	0.492	0.422	0.497	0.936	0.146
Compound_394	CO[C@H]1C[C@H]2N(C1)CCN(C2)c1cc2c(cc1NC(=O)c1cnn3c1nccc3)cn(c2O)C[C@H](C(O)(C)C)F	0.658	0.728	0.07	0.41	0.675	0.652	0.965	0.58	0.389	0.962	0.541
Compound_395	OC(=O)CCC1CN(c2c1ccc(c2)c1cc(F)cc(c1)OC(F)F)S(=O)(=O)c1cccc(c1)C(F)(F)F	0.574	0.539	0.709	0.442	0.701	0.772	0.997	0.201	0.369	0.132	0.39
Compound_396	CCn1nc(c(c1)S(=O)(=O)N1C[C@H](CCc2n[nH]c(=O)o2)Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)Cl	0.671	0.579	0.596	0.607	0.545	0.621	0.819	0.739	0.392	0.97	0.495
Compound_397	CC(Oc1c(nc2c(c1Cl)cc(cc2)[C@@](c1cnc(n1C)C)(c1cnnn1C)O)N1CCC1)C	0.583	0.613	0.01	0.436	0.645	0.645	0.955	0.145	0.616	0.756	0.483
Compound_398	Fc1cccc(c1c1nnc2c(c1)[C@@H]1CC[C@]2(C1(C)C)c1ccnc(n1)c1cncn1CCS(=O)(=O)C)F	0.59	0.6	0.137	0.687	0.681	0.645	0.993	0.947	0.414	0.366	0.384
Compound_399	CC[C@@H](C(F)(F)F)N=c1[nH]cc(c(c1)C(F)F)c1sc(nc1C(=O)N1C2CCC1CC2)C(=O)N[C@@H]1COC[C@H]1O	0.655	0.443	0.207	0.393	0.586	0.66	0.066	0.518	0.249	0.218	0.375
Compound_400	CCS(=O)(=O)c1ccc(cc1)CC(=O)Nc1ccc(cc1)OC(c1ccc(cc1Cl)Cl)(C)C	0.29	0.533	0.969	0.703	0.935	0.796	0.616	0.789	0.374	0.93	0.317
Compound_401	OC(=O)CC1CCN(CC1)C(=O)c1ccc(c(c1Cl)Cc1cc2c(n1C)cc(cc2)OC(F)(F)F)Cl	0.505	0.573	0.796	0.456	0.942	0.779	0.982	0.482	0.409	0.554	0.67
Compound_402	CC(NC(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1ccc(cc1)F)NC(=O)OC(C(F)(F)F)(C)C)C	0.643	0.579	0.871	0.598	0.728	0.628	0.354	0.713	0.333	0.46	0.53
Compound_403	OCCc1ncn(n1)c1nccc(n1)[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.601	0.635	0.659	0.639	0.645	0.638	0.865	0.535	0.42	0.003	0.663
Compound_404	N#Cc1cc(=NC2CCCCC2)[nH]cc1c1sc(nc1C(=O)N1CCC(CC1)F)C(=O)NCC(O)(C)C	0.666	0.52	0.063	0.417	0.378	0.628	0.006	0.736	0.439	0.005	0.187
Compound_405	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CCN1CCCC1=O)S(=O)(=O)c1cccc(c1)C(F)(F)F	0.644	0.588	0.322	0.641	0.555	0.626	0.91	0.941	0.342	0.582	0.5
Compound_406	O=C1/C(=C\c2c(Cl)cccc2Br)/c2c(N1c1ccc(c(c1)O)C(=O)O)cccc2C	0.557	0.764	0.304	0.367	0.5	0.668	0.998	0.428	0.442	0.986	0.849
Compound_407	CCS(=O)(=O)c1ccc(cc1)CNC(=O)c1ccc2c(c1)nc(n2C1CC1)C(=O)c1ccc(cc1)C(F)(F)F	0.311	0.526	0.254	0.498	0.752	0.695	0.996	0.959	0.395	0.094	0.259
Compound_408	N#Cc1ccc(cc1)[C@H](N1Cc2c([C@@H]1C(C)C)[nH]c(=NC(=O)Cc1ccc(cc1)S(=O)(=O)C)s2)C	0.413	0.579	0.059	0.284	0.391	0.66	0.312	0.148	0.389	0.477	0.402
Compound_409	OCC(c1nnc(o1)C[C@@H]1CCc2c(N1S(=O)(=O)c1ccc(cc1)F)ccc(c2)C(C(F)(F)F)(C(F)(F)F)O)(O)C	0.688	0.566	0.637	0.601	0.62	0.61	0.841	0.381	0.376	0.016	0.475
Compound_410	O=C(OC(C)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNS(=O)(=O)C)S(=O)(=O)c1cn(nc1C)C(F)F	0.696	0.624	0.32	0.621	0.52	0.618	0.471	0.975	0.405	0.801	0.614
Compound_411	N#Cc1cc(C)c2c(c1)n(C)c(c2)Cc1c(Cl)ccc(c1Cl)C(=O)N1CCC2(CC1)COCC2	0.655	0.633	0.837	0.56	0.849	0.692	0.991	0.905	0.461	0.372	0.889
Compound_412	CCn1ncc(c1C)CNC(=O)C[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)C(F)(F)F)NC(=O)OC(C)(C)C	0.655	0.609	0.564	0.573	0.574	0.646	0.716	0.924	0.354	0.956	0.5
Compound_413	N#CCCN1C(=O)CCC1C(=O)N[C@@H]1CC[C@@]2([C@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccc(cc1)F	0.654	0.478	0.21	0.389	0.617	0.587	0.4	0.806	0.396	0.772	0.443
Compound_414	CN(CCN1CCN(CC1)c1cc2OC(Cc2cc1NC(=O)c1cnn2c1nccc2)(C)C)C	0.372	0.768	0.001	0.332	0.542	0.701	0.704	0.073	0.443	0.898	0.208
Compound_415	CCn1nc(c(c1)S(=O)(=O)N1CC(Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)C(=O)C(F)(F)F)Cl	0.694	0.586	0.804	0.657	0.526	0.574	0.697	0.92	0.395	0.815	0.589
Compound_416	CC(=O)N=c1cc(n([nH]1)C1CCC1)c1ccc(c(c1)N1CC2C(C1)C2)N(C(=O)c1c(F)cccc1Cl)C	0.689	0.618	0.102	0.526	0.745	0.663	0.826	0.358	0.474	0.007	0.106
Compound_417	NC(=O)CCc1ncn(n1)c1cncc(n1)[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.587	0.667	0.043	0.478	0.657	0.644	0.988	0.85	0.511	0.001	0.154
Compound_418	C[C@H]1CC(CN1C(=O)c1nc(sc1c1c[nH]c(=NC(C2CC2)(C)C)cc1C(F)F)C(=O)NCC(O)(C)C)(F)F	0.668	0.559	0.204	0.41	0.5	0.67	0.143	0.776	0.373	0.24	0.213
Compound_419	CCS(=O)(=O)c1ccc(cc1)C(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1ccc(cc1)F)NC(=O)OC(C(F)(F)F)(C)C	0.698	0.559	0.861	0.559	0.786	0.654	0.277	0.918	0.395	0.897	0.539
Compound_420	O=C(OC(C)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CCNC(=O)C(C)C)S(=O)(=O)c1cccc(c1)C(F)(F)F	0.625	0.649	0.195	0.506	0.444	0.676	0.464	0.921	0.364	0.843	0.506
Compound_421	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CC(C(=O)O)(C)C)S(=O)(=O)c1c(Cl)nn2c1CCCC2	0.675	0.649	0.362	0.565	0.631	0.649	0.958	0.847	0.359	0.944	0.547
Compound_422	Fc1ccc(cc1)S(=O)(=O)[C@@]1(CC[C@@H](CC1)NC(=O)c1ccnnc1)c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)F	0.449	0.421	0.237	0.452	0.735	0.499	0.369	0.46	0.42	0.048	0.215
Compound_423	CC(Oc1cc2c(cc1NC(=O)c1cnn3c1ncc(c3)C)cn(c2O)C[C@H](C(O)(C)C)F)C	0.695	0.648	0.366	0.616	0.667	0.65	0.961	0.502	0.462	0.798	0.605
Compound_424	O=C1/C(=C\c2c(Cl)cccc2C2CC2)/c2c(N1c1ccc(c(c1)O)C(=O)O)cccc2C	0.538	0.794	0.299	0.373	0.98	0.568	0.995	0.421	0.413	0.969	0.747
Compound_425	CCN(C(=O)c1ccc(nn1)CS(=O)(=O)C)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.62	0.699	0.193	0.677	0.548	0.621	0.907	0.668	0.431	0.842	0.265
Compound_426	Fc1cc(C(=O)O)c(cc1c1nn(c2c1c(F)ccc2)Cc1c(F)cccc1Cl)O	0.496	0.555	0.854	0.403	0.972	0.728	0.995	0.805	0.476	0.061	0.761
Compound_427	OC[C@@H](c1ccc(cc1)S(=O)(=O)CC)NC(=O)c1ccc2c(c1)nc(n2Cc1cccc2c1OC(O2)(F)F)C1CC1	0.505	0.453	0.101	0.482	0.733	0.686	0.988	0.268	0.387	0.487	0.363
Compound_428	OC(=O)C1CC(C1)NC(=O)c1nc(c(s1)c1cnc(c2c1cccc2)S(=O)(=O)NC(C)(C)C)CC1CCCCC1	0.628	0.604	0.055	0.407	0.476	0.654	0.893	0.705	0.347	0.987	0.251
Compound_429	N#CCc1cc(ccc1OCC1CCOCC1)S(=O)(=O)N(c1ccc(cc1)CC)CC(C)C	0.527	0.649	0.854	0.566	0.485	0.747	0.683	0.886	0.31	0.662	0.475
Compound_430	OC(=O)c1ccc(cc1O)n1cc(c2c1c(F)ccc2)C(=O)c1c(Cl)cccc1C(F)(F)F	0.476	0.534	0.198	0.39	0.901	0.583	0.997	0.948	0.213	0.253	0.957
Compound_431	Clc1cccc(c1C(=O)c1cn(c2c1cccc2)c1ccc(c(c1)O)C(=O)O)Cl	0.393	0.628	0.743	0.402	0.89	0.653	0.993	0.844	0.173	0.301	0.946
Compound_432	C[C@H]1CC(CN1C(=O)c1nc(sc1c1c[nH]c(=N[C@H](C(F)(F)F)C2CC2)cc1C(F)F)C(=O)N[C@@H](C(O)(C)C)C)(F)F	0.671	0.488	0.536	0.497	0.5	0.64	0.039	0.811	0.319	0.148	0.216
Compound_433	CCn1nc(c(c1)S(=O)(=O)N1C[C@@H](Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)[C@@H](NC(=O)C)C)Cl	0.685	0.566	0.804	0.591	0.5	0.594	0.615	0.866	0.363	0.944	0.576
Compound_434	O=C(C[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1cccc(c1)C(F)(F)F)NC(=O)OC(C)(C)C)NCC1CC1	0.626	0.579	0.229	0.512	0.548	0.621	0.399	0.915	0.361	0.805	0.5
Compound_435	N#Cc1ccc(cn1)CN1Cc2c([C@@H]1C(C)C)[nH]c(=NC(=O)Cc1ccc(cc1)S(=O)(=O)CC)s2	0.473	0.589	0.098	0.213	0.401	0.661	0.01	0.492	0.367	0.224	0.417
Compound_436	C[C@H]1CC(CN1C(=O)c1nc(sc1c1c[nH]c(=NC2(C)CCC2)cc1C(F)(F)F)C(=O)N[C@H](C(O)(C)C)C)(F)F	0.667	0.428	0.094	0.444	0.532	0.647	0.039	0.834	0.279	0.122	0.202
Compound_437	OCCOc1nn(cc1S(=O)(=O)N1C[C@@H](Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)[C@H](C1CC1)NC(=O)C(O)(C)C)CC	0.714	0.699	0.262	0.567	0.53	0.626	0.423	0.719	0.385	0.877	0.465
Compound_438	CCn1nc(c(c1c1c(F)cc(cc1F)CC(C(F)(F)F)C)Cl)C(=O)NC[C@@H]1CC[C@H](CC1)S(=O)(=O)C	0.595	0.699	0.451	0.527	0.718	0.742	0.941	0.981	0.429	0.838	0.265
Compound_439	CCn1nc(c(c1c1ccc(cc1OC(F)F)CC(CC(F)(F)F)(C)C)Cl)C(=O)NC[C@]1(O)CC[C@H](CC1)S(=O)(=O)C	0.713	0.729	0.154	0.509	0.741	0.708	0.602	0.954	0.408	0.991	0.406
Compound_440	OC(=O)CC1CCN(CC1)C(=O)c1ncc(c(c1Cl)Cn1cc(c2c1c(C)cc(c2)C(F)(F)F)C)Cl	0.628	0.722	0.681	0.45	0.389	0.678	0.992	0.74	0.378	0.305	0.228
Compound_441	OC[C@H](c1ccc(cn1)S(=O)(=O)CC)NC(=O)c1cnc2c(c1)CN(C2C(C)C)C[C@@H]1CC[C@H](CC1)C(F)(F)F	0.574	0.626	0.015	0.189	0.28	0.587	0.817	0.262	0.355	0.876	0.384
Compound_442	CCn1nc(c(c1c1ccc(cc1OC(F)F)C[C@H](C(F)(F)F)C)C)C(=O)NC[C@]1(O)CC[C@H](C[C@H]1O)S(=O)(=O)C	0.719	0.709	0.152	0.574	0.673	0.656	0.623	0.956	0.399	0.905	0.409
Compound_443	C[C@@H]([C@@H](NC(=O)c1nc(c(s1)c1c[nH]c(=NC(C)(C)C)cc1C(F)(F)F)C(=O)N1CCC[C@@H]1C)C)O	0.61	0.458	0.04	0.427	0.261	0.609	0.079	0.865	0.237	0.069	0.221
Compound_444	N#C[C@@]1(CC[C@@H](CC1)S(=O)(=O)C)CNC(=O)c1nn(c(c1Cl)c1ccc(cc1)CC(C(F)(F)F)(C)C)CC	0.689	0.709	0.107	0.469	0.761	0.76	0.928	0.973	0.451	0.849	0.459
Compound_445	OC(=O)CC[C@@H]1Oc2c(F)cc(cc2N(C1)S(=O)(=O)c1ccnc(c1)C(F)(F)F)NC(=O)OC(C(F)(F)F)(C)C	0.689	0.629	0.403	0.601	0.491	0.595	0.821	0.949	0.363	0.164	0.522
Compound_446	OC(=O)c1ccc(cc1)N1c2cccc(c2/C(=C\c2c(Cl)cccc2C(F)(F)F)/C1=O)F	0.538	0.651	0.249	0.383	0.979	0.871	0.997	0.991	0.383	0.932	0.823
Compound_447	Fc1cc(N2CC3[C@H](C2)[C@H]3n2cnnc2)c(cc1CN1[C@H](CC[C@@H](S1(=O)=O)c1ccccc1)C(F)(F)F)F	0.633	0.555	0.652	0.642	0.667	0.797	0.933	0.869	0.392	0.167	0.343
Compound_448	Fc1ccc(cc1)S(=O)(=O)[C@@]1(CC[C@@H](CC1)N1CCS(=O)(=O)CC1)c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)F	0.362	0.46	0.083	0.192	0.731	0.592	0.689	0.611	0.361	0.096	0.26
Compound_449	N#Cc1cccc(c1)N(S(=O)(=O)c1ccc(cc1)OC1CCN(CC1)S(=O)(=O)C)CC(C)C	0.446	0.646	0.786	0.575	0.557	0.593	0.318	0.55	0.38	0.587	0.379
Compound_450	COc1nc2ccc(cc2c(c1C1CCCC1)Cl)[C@@](c1cnnn1C)(c1ccc(nc1C)C)O	0.598	0.755	0.206	0.572	0.682	0.649	0.963	0.218	0.524	0.991	0.447
Compound_451	CC(=O)NC1Cc2ncc(cc2N(C1)S(=O)(=O)c1cccc(c1)C1CC1)NC(=O)c1c(Cl)cccc1Cl	0.631	0.541	0.272	0.503	0.52	0.748	0.811	0.82	0.403	0.228	0.291
Compound_452	COC(=O)C1CCC(=CC1)c1nn(c2c1CCC(C2)C(=O)O)C(=O)c1c(Cl)cccc1C1CC1	0.764	0.73	0.304	0.371	0.781	0.762	0.89	0.659	0.411	0.786	0.386
Compound_453	CCS(=O)(=O)c1ccc(cc1)CC(=O)N=c1sc2c([nH]1)C(N(C2)Cc1ccc(cc1)F)Cc1cccc(c1)Br	0.482	0.611	0.172	0.293	0.676	0.646	0.288	0.266	0.379	0.685	0.409
Compound_454	CCS(=O)(=O)c1ccc(cc1)CNC(=O)c1ccc2c(c1)nc(n2Cc1cccc2c1OC(O2)(F)F)C(C)C	0.478	0.535	0.346	0.474	0.726	0.696	0.927	0.844	0.379	0.646	0.347
Compound_455	CC[C@@H](C(F)(F)F)N=c1[nH]cc(c(c1)C(F)F)c1sc(nc1C(=O)N1CCC[C@@H]1C)C(=O)NC1CN(C1)S(=O)(=O)C	0.614	0.448	0.328	0.451	0.402	0.499	0.024	0.742	0.362	0.669	0.45
Compound_456	COC(=O)COc1nn(cc1S(=O)(=O)N1C[C@@H](Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)[C@H](C1CC1)NC(=O)C)CC	0.73	0.716	0.15	0.634	0.531	0.626	0.655	0.948	0.405	0.977	0.487
Compound_457	CCS(=O)(=O)c1ccc(nc1)[C@H](NC(=O)c1cnc2c(c1)CN(C2C(C)C)C[C@@H]1CC[C@@H](CC1)C(F)(F)F)COC(=O)N	0.656	0.626	0.036	0.181	0.315	0.602	0.748	0.504	0.368	0.961	0.45
Compound_458	CC(CCC[C@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2[C@@H](O)C=C2[C@]1(C)CC[C@@H](C2)O)C)C	0.986	0.99	0.184	0.746	0.961	0.957	0.009	0.827	0.071	0.998	0.472
Compound_459	O[C@@H]1CCC[C@H]1NC(=O)c1nc(c(s1)c1c[nH]c(=N[C@H](C(F)(F)F)C)cc1C(F)F)C(=O)N1CCC[C@@H]1C	0.623	0.49	0.088	0.487	0.444	0.588	0.09	0.867	0.151	0.001	0.165
Compound_460	OC[C@@H](Cn1ccc(n1)c1cccc(n1)[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F)O	0.592	0.694	0.834	0.661	0.664	0.624	0.93	0.266	0.405	0.004	0.443
Compound_461	Fc1cc(CN2CCN([C@H](C2)C)C(=O)C2CCCC2)c(c(c1)NC(=O)c1ccc(nc1)C)C	0.314	0.634	0.753	0.351	0.06	0.484	0.428	0.679	0.328	0.724	0.04
Compound_462	Fc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)C12CCC(CC1)(CC2)C(=O)O)c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)F	0.474	0.578	0.35	0.475	0.762	0.525	0.713	0.761	0.387	0.266	0.292
Compound_463	O[C@@H]1CCC[C@H]1NC(=O)c1nc(c(s1)c1c[nH]c(=NC(C)(C)C)cc1C(F)(F)F)C(=O)N1CCC[C@@H]1C	0.616	0.559	0.018	0.449	0.314	0.598	0.09	0.867	0.212	0.032	0.24
Compound_464	CN1CC(C1)NC(=O)c1nc(c(s1)c1c[nH]c(=NC(C)(C)C)cc1C(F)(F)F)C(=O)N1CCC[C@@H]1C	0.59	0.529	0.028	0.332	0.272	0.468	0.026	0.618	0.349	0.061	0.224
Compound_465	OC(=O)C1CCC(=CC1)c1nn(c2c1CCC(C2)C(=O)N1CC2(C1)CCCO2)C(=O)c1c(ccc(c1Cl)F)C1CC1	0.801	0.682	0.177	0.396	0.765	0.679	0.813	0.926	0.397	0.643	0.407
Compound_466	COc1cc(CCCC(F)(F)F)ccc1c1n(CC)nc(c1C)C(=O)NC[C@@H]1CC[C@H](CC1)S(=O)(=O)C	0.751	0.639	0.554	0.571	0.567	0.712	0.689	0.966	0.456	0.917	0.304
Compound_467	CC(=O)C(NCc1coc(n1)c1cncc(n1)[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F)O	0.666	0.704	0.369	0.538	0.681	0.652	0.991	0.877	0.444	0.03	0.245
Compound_468	CCn1nc(c(c1c1c[nH]c(=NC(CC(F)(F)F)(C)C)cc1OC(F)F)Cl)C(=O)NC[C@@]1(O)CC[C@@H](C[C@@H]1O)S(=O)(=O)C	0.685	0.589	0.02	0.482	0.647	0.674	0.686	0.811	0.405	0.87	0.373
Compound_469	CCN(C(=O)C1CN(C1)C(=O)C)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.454	0.694	0.318	0.654	0.514	0.576	0.064	0.577	0.462	0.939	0.283
Compound_470	C[C@H]1CCCN1C(=O)c1nc(sc1c1c[nH]c(=NC(C)(C)C)cc1C(F)(F)F)C(=O)NCC(C(F)(F)F)(C(F)(F)F)O	0.61	0.518	0.029	0.385	0.424	0.637	0.027	0.809	0.253	0.086	0.233
Compound_471	COC1CC(C1)C(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1ccc(cc1)F)NC(=O)OC(C(F)(F)F)(C)C	0.688	0.609	0.599	0.596	0.756	0.649	0.072	0.842	0.377	0.951	0.537
Compound_472	CCN(C(=O)C1CN(C1)S(=O)(=O)C)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.45	0.709	0.27	0.684	0.527	0.598	0.107	0.653	0.404	0.937	0.511
Compound_473	O=C(C[C@@H]1CCc2c(N1S(=O)(=O)c1ccc(cc1)F)ccc(c2)C(C(F)(F)F)(C(F)(F)F)O)NCC(O)(C)C	0.655	0.569	0.083	0.343	0.555	0.601	0.391	0.267	0.344	0.066	0.38
Compound_474	OCC1CCc2c(C1)n(nc2C1=CCC(CC1)C(=O)O)C(=O)c1c(Cl)cccc1C1(CC1)C(F)(F)F	0.763	0.702	0.126	0.48	0.861	0.778	0.851	0.474	0.308	0.348	0.586
Compound_475	CC(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1ccc(cc1)F)NC(=O)OC(C(F)(F)F)Cc1ccccc1	0.675	0.408	0.886	0.58	0.76	0.631	0.173	0.849	0.358	0.408	0.492
Compound_476	CCN(C(=O)c1ccc(cc1)c1ncccn1)C[C@@]12CC[C@H](C2(C)C)c2c1nnc(c2)c1c(F)cccc1F	0.478	0.744	0.346	0.733	0.622	0.632	0.944	0.658	0.436	0.947	0.126
Compound_477	CCn1nc(c(c1c1ccc(cc1OC(F)F)CC(C(F)(F)F)C(F)(F)F)Cl)C(=O)NC[C@@H]1CC[C@H](CC1)S(=O)(=O)C	0.681	0.629	0.425	0.53	0.709	0.725	0.704	0.955	0.418	0.695	0.306
Compound_478	C[C@H]1CCCN1C(=O)c1nc(sc1c1c[nH]c(=NC2(CCC2)C(F)(F)F)cc1C(F)F)C(=O)NCC(O)(C)C	0.641	0.488	0.147	0.398	0.546	0.647	0.03	0.745	0.294	0.086	0.256
Compound_479	CC[C@@H](C(F)(F)F)N=c1[nH]cc(c(c1)C(F)(F)F)c1sc(nc1C(=O)N1CC(C[C@@H]1C)(F)F)C(=O)NCC(O)(C)C	0.653	0.488	0.151	0.441	0.442	0.618	0.027	0.215	0.224	0.143	0.232
Compound_480	N#Cc1c(nn(c1c1ccc(cc1OC)CC(C(F)(F)F)(C)C)CC)C(=O)NC[C@]1(O)CC[C@H](CC1)S(=O)(=O)C	0.734	0.699	0.226	0.597	0.716	0.665	0.615	0.981	0.444	0.975	0.507
Compound_481	CCS(=O)(=O)c1ccc(cc1)CC(=O)Nc1ccc(cc1)CCN1CCCc2c1cc(C)cc2	0.388	0.558	0.178	0.471	0.709	0.561	0.945	0.342	0.386	0.115	0.097
Compound_482	N#Cc1cc(C)c2c(c1)n(C)c(c2)Cc1c(Cl)ncc(c1Cl)C(=O)N1CCOCC1	0.56	0.649	0.637	0.54	0.297	0.615	0.998	0.772	0.417	0.365	0.773
Compound_483	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNC(=O)C(O)(C)C)S(=O)(=O)c1ccc(cc1)F	0.658	0.649	0.921	0.553	0.575	0.604	0.084	0.635	0.333	0.749	0.513
Compound_484	N#CCCN1C(=O)CCC1C(=O)N1CC[C@@]2([C@H]1CCc1c2cnc(c1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccc(cc1)F	0.692	0.526	0.561	0.474	0.728	0.585	0.234	0.803	0.397	0.753	0.5
Compound_485	Fc1ccc(cc1)S(=O)(=O)C1(CC(C1)C(=O)N1CCOCC1)c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)OCc1c(F)cccc1F	0.301	0.561	0.468	0.625	0.824	0.645	0.901	0.799	0.404	0.832	0.426
Compound_486	OC(=O)CC1CCN(CC1)C(=O)c1ccc(c(c1Cl)Cn1ccc2c1ccc(c2)C(C)C)Cl	0.588	0.557	0.545	0.383	0.596	0.724	0.994	0.414	0.417	0.252	0.115
Compound_487	COC(=O)C1CCOCC1c1cc(F)c(cc1F)CN1[C@@H](C)CC[C@@H](S1(=O)=O)c1ccccc1	0.652	0.739	0.362	0.571	0.183	0.515	0.861	0.848	0.401	0.34	0.52
Compound_488	COc1nc2ccc(cc2c(c1CC(C)C)Cl)[C@](c1cnnn1C)(c1ccc(nc1C)C)O	0.559	0.737	0.082	0.565	0.647	0.647	0.963	0.757	0.525	0.956	0.495
Compound_489	N#C[C@@]1(CC[C@@H](CC1)S(=O)(=O)C)CNC(=O)c1nn(c(c1Cl)c1ccc(cc1OC)N[C@@H](C(F)(F)F)C)CC	0.695	0.669	0.175	0.45	0.764	0.695	0.805	0.917	0.439	0.977	0.53
Compound_490	C[C@@H](COc1nn2c(c1S(=O)(=O)N1C[C@H](CNC(=O)C)Oc3c1cc(cc3)NC(=O)OC(C(F)(F)F)(C)C)CCCC2)O	0.695	0.698	0.029	0.454	0.593	0.654	0.514	0.604	0.377	0.377	0.406
Compound_491	CC[C@@H](C(F)(F)F)N=c1[nH]cc(c(c1)C(F)F)c1sc(nc1C(=O)N1CCC[C@@H]1C)C(=O)N[C@@H]1C[C@H](C1)O	0.62	0.448	0.21	0.451	0.507	0.646	0.079	0.438	0.247	0.001	0.24
Compound_492	OC(=O)C(Cc1nc(c(s1)c1ccc(c(c1Cl)Cl)S(=O)(=O)N[C@H](C(F)(F)F)C)CC1CCC1)(C)C	0.49	0.569	0.204	0.493	0.704	0.653	0.962	0.934	0.336	0.961	0.451
Compound_493	O=C(c1nc(c(s1)c1cnc(c2c1cccc2)S(=O)(=O)NC(C)(C)C)CC1CCCCC1)NCC(O)(C)C	0.605	0.634	0.293	0.4	0.336	0.701	0.819	0.92	0.246	0.895	0.206
Compound_494	O=C(OC(C)(C)C)Nc1ccc2c(c1)N(C[C@H](O2)CC(=O)N1CCOC1)S(=O)(=O)c1cccc(c1)C(F)(F)F	0.624	0.669	0.18	0.576	0.464	0.615	0.91	0.924	0.33	0.992	0.599
Compound_495	FCCC(NS(=O)(=O)c1ccc(c2c1cccc2)c1sc(nc1CC1CCCCC1)C(=O)NC1CC(C1)C(=O)O)(C)C	0.567	0.654	0.031	0.456	0.627	0.655	0.948	0.899	0.39	0.526	0.316
Compound_496	O=C(OC(C)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CS(=O)(=O)C(C)(C)C)S(=O)(=O)c1cccc(c1)C(F)(F)F	0.563	0.649	0.347	0.652	0.593	0.68	0.881	0.946	0.387	0.911	0.553
Compound_497	CCn1nc(c(c1)S(=O)(=O)N1C[C@@H](Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)CC(C(=O)O)(CO)C)Cl	0.688	0.669	0.443	0.617	0.541	0.58	0.767	0.626	0.332	0.962	0.573
Compound_498	CC(=O)NC(C[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1ccc(cc1)F)NC(=O)OC(C(F)(F)F)(C)C)(C)C	0.668	0.649	0.796	0.655	0.603	0.658	0.899	0.865	0.367	0.95	0.532
Compound_499	N#Cc1ccccc1COC(C(F)(F)F)(C(F)(F)F)c1ccc(cc1)C1(CCCC1)S(=O)(=O)c1ccc(cc1)F	0.769	0.633	0.38	0.64	0.96	0.703	0.854	0.862	0.402	0.85	0.659
Compound_500	Fc1ccc(cc1)S(=O)(=O)[C@@]12CCN([C@@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)C(=O)C1CCN(CC1)C(=O)C	0.591	0.656	0.393	0.52	0.537	0.391	0.305	0.895	0.403	0.368	0.295
Compound_501	O=C(OC(C)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)CNS(=O)(=O)C1CC1)S(=O)(=O)c1cccc(c1)S(=O)(=O)C	0.611	0.629	0.261	0.566	0.506	0.664	0.069	0.932	0.4	0.93	0.453
Compound_502	CCCOc1ncccc1c1csc(c1)NC(=O)Cc1ccc(cc1)S(=O)(=O)CC	0.634	0.578	0.409	0.558	0.241	0.728	0.887	0.765	0.366	0.027	0.126
Compound_503	C[C@H]1CC(CCC1C(=O)N1CC[C@@]2([C@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccccc1)C(=O)O	0.575	0.699	0.109	0.398	0.67	0.506	0.802	0.875	0.399	0.537	0.29
Compound_504	CNS(=O)(=O)NC[C@@H]1Oc2ccc(cc2N(C1)S(=O)(=O)c1ccc(cc1)F)NC(=O)OC(C(F)(F)F)(C)C	0.671	0.659	0.866	0.615	0.722	0.654	0.303	0.911	0.342	0.85	0.53
Compound_505	N#Cc1cc(ccc1c1n(CC)nc(c1Cl)C(=O)NC[C@]1(O)CC[C@H](CC1)S(=O)(=O)C)CC(C(F)(F)F)(C)C	0.732	0.699	0.049	0.54	0.757	0.692	0.799	0.981	0.445	0.987	0.507
Compound_506	CCOc1nn(cc1S(=O)(=O)N1C[C@H](CNC(=O)C(C(F)(F)F)(N)C)Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)C(F)F	0.733	0.629	0.166	0.486	0.548	0.616	0.336	0.66	0.316	0.693	0.508
Compound_507	CC(=O)N1CCN(C[C@H]1C)c1ccc2c(c1)CCN(C2)S(=O)(=O)N(Cc1c(F)cccc1Cl)C	0.361	0.718	0.268	0.511	0.635	0.775	0.313	0.952	0.404	0.86	0.351
Compound_508	CCS(=O)(=O)c1ccc(cc1)CNC(=O)c1ccc2c(c1)nc(n2Cc1cccc(c1)OC(F)(F)F)C1CC1	0.414	0.554	0.276	0.532	0.761	0.729	0.966	0.828	0.388	0.229	0.299
Compound_509	O=C(OC(C)(C)C)Nc1ccc2c(c1)N(C[C@@H](O2)Cn1nncc1)S(=O)(=O)c1cn(nc1C)C(F)F	0.661	0.596	0.336	0.649	0.561	0.617	0.809	0.977	0.38	0.805	0.578
Compound_510	CNC(=O)N=c1cc(n([nH]1)C(C)C)c1ccc(c(c1)N1CC2C(C1)C2)N(C(=O)c1c(F)cccc1Cl)C	0.72	0.654	0.07	0.492	0.619	0.786	0.978	0.479	0.511	0.283	0.238
Compound_511	OCCOc1nn(cc1S(=O)(=O)N1C[C@H](CNC(=O)C(C(F)(F)F)(N)C)Oc2c1cc(cc2)NC(=O)OC(C(F)(F)F)(C)C)C(F)F	0.71	0.699	0.089	0.452	0.554	0.616	0.315	0.487	0.329	0.418	0.456
Compound_512	O=C(OC(C(F)(F)F)(C)C)Nc1ccc2c(c1)N(C[C@H](O2)CC1(CC1)C(=O)O)S(=O)(=O)c1ccc(c(c1)C)F	0.72	0.619	0.859	0.636	0.637	0.619	0.914	0.738	0.375	0.987	0.578
Compound_513	CC(CN(S(=O)(=O)c1ccc(cc1)c1ccc(cc1)C(=O)N)c1ccccc1Cl)C	0.469	0.485	0.764	0.456	0.747	0.732	0.988	0.075	0.409	0.313	0.249
Compound_514	O=C(C1N(Cc2c1ccc(c2)S(=O)(=O)CC1CC1)C(=O)C1CCCO1)Nc1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)O	0.629	0.586	0.255	0.638	0.74	0.647	0.898	0.608	0.383	0.794	0.484
Compound_515	OC[C@@H](CNC(=O)C1CC[C@@]2([C@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)S(=O)(=O)c1ccc(cc1)F)O	0.531	0.579	0.082	0.224	0.619	0.656	0.578	0.202	0.399	0.297	0.367
Compound_516	OC(=O)c1ccc(c(c1)F)c1nn(c2c1CCOC2)C(=O)c1c(Cl)cccc1C1(CC1)C(F)(F)F	0.59	0.68	0.253	0.565	0.902	0.72	0.966	0.748	0.413	0.161	0.614