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Jie Li (Jana)

PhD Candidate
Shanghai Key Laboratory of New Drug Design
School of Pharmacy
East China University of Science and Technology
130 Meilong Road, Shanghai 200237, China
Tel: +86-21-6425-1190
Tel: +86-138-1869-2096
lijie1989bd@gmail.com
li_jie_69@163.com

Education Background

2012.9 - Present East China University of Science and Technology, School of Pharmacy, Pharmaceutical Science (Ph.D.)
2008.9 - 2012.6 East China University of Science and Technology, School of Pharmacy, Pharmaceutical Engineering (B.S.)

Research Focus

Network Pharmacology: developing computational methods for network-based prediction of pharmacogenomics, involving noncoding RNAs (miRNA and LncRNA).
ADMET Prediction: webserver construction, model building to assess chemical safety, substructure alerts mining, and computational systems toxicology.
System-based Drug Design: anticancer and anti-diabetic drug design, combining the traditional drug design methods with systems biology.

Publications

  • ZR Wu, FX Cheng, J Li, WH Li, GX Liu, Y Tang. SDTNBI: an integrated network and chemoinformatics tool for systematic prediction of drug-target interactions and drug repositioning. Brief. Bioinform., 2016, accepted.
  • J Li, KJ Li, C Zhang, QP Peng, Y Tang. Computational systems toxicology: emergence, development and application (in Chinese). Chin. Sci. Bull., 2015, 60: 1751-1760.
  • J Li, ZR Wu, FX Cheng, WH Li, GX Liu, Y Tang. Computational prediction of microRNA networks incorporating environmental toxicity and disease etiology. Sci. Rep., 2014, 4: 5576.
  • FX Cheng, WH Li, YD Zhou, J Li, J Shen, P. W. Lee and Y Tang. Prediction of Human Genes and Diseases Targeted by Xenobiotics Using Predictive Toxicogenomics-Derived Models (PTDMs). Mol. BioSyst., 2013, 9: 1316-1325.
  • FX Cheng, WH Li, ZR Wu, XC Wang, C Zhang, J Li, GX Liu and Y Tang. Prediction of Polypharmacological Profiles of Drugs by the Integration of Chemical, Side Effects and Therapeutic Space. J. Chem. Inf. Model., 2013, 53 (4): 753-762.
  • FX Cheng, YD Zhou, J Li, WH Li, GX Liu and Y Tang. Prediction of Chemical-Protein Interactions: Multitarget-QSAR versus Computational Chemogenomic Methods. Mol. BioSyst., 2012, 8:2373-2384.
  • ZJ Xu, FX Cheng, J Li,YD Zhou, N Su, WH Li, GX Liu and Y Tang. Comparative pharmacophore modeling of human adenosine receptor A1 and A3 antagonists. Sci China Chem, 2012, 55(11): 2407-2418.