Adverse drug event (ADE) is defined as an injury during medication administration related to medicine, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. ADEs lead to an enormous amount of morbidity and mortality. Previous studies showed that about 6% of patients were hospitalized due to ADE in the U.S., and ADEs caused 197,000 deaths in Europe per year. The more People usually take medicines as they age, the more the risk of adverse events may take place. The good news is the most of ADEs are preventable. So reducing adverse drug events is urgent to detect or determine ADEs and prevent the occurrence of ADEs.