Tutorial

Basic Search

MetaADEDB2.1 provides basic search for drug (ADE) names and identifiers. Users can select the type of interest from the drop-down menu, and then enter the information they want to search for in the text box. It should be noted that for drug identifiers, the website provides precise search, and users need to provide the complete identifier of the drug.

Structure Similarity Search

MetaADEDB2.1 provides structure similarity search for drug. Users can click the button in the upper right corner to enter the page shown in the figure. Then, users can draw the structure of compound in the molecular editor or input the SMILES of compound in the text box, select the type of fingerprint for comparison in the drop-down menu, and click the search button to search.

Preliminary Result Display

Users can select the number of compounds displayed on each page from the drop-down menu. Then, users can click on the name of the compounds or ADEs to enter the "detail information display" page

Drug Result Display

MetaADEDB2.1 provides seven modules as shown in the left figure. In the "ADEs" and "Indications" modules, users can select the number of compounds displayed in the table from the drop-down menu, search for the name of ADE (Indication) in the box on the right, and finally click on the number under "FAERS Frequency" ("CVAROD Frequency") to enter the "detail report display" page

ADE Result Display

MetaADEDB2.1 provides five modules as shown in the left figure. In the "ADEs" and "Indications" modules, users can select the number of ADEs displayed in the table from the drop-down menu, search for the compound names in the box on the right, and finally click on the number under "FAERS Frequency" ("CVAROD Frequency") to enter the "detail report display" page